CN104383329A - Traditional Chinese medicine preparation for treating acute nephritis - Google Patents

Traditional Chinese medicine preparation for treating acute nephritis Download PDF

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CN104383329A
CN104383329A CN201410655585.0A CN201410655585A CN104383329A CN 104383329 A CN104383329 A CN 104383329A CN 201410655585 A CN201410655585 A CN 201410655585A CN 104383329 A CN104383329 A CN 104383329A
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景东旭
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/80Scrophulariaceae (Figwort family)
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating acute nephritis. The traditional Chinese medicine preparation is characterized by respectively comprising the following selected traditional Chinese medicine raw materials in parts by weight: 30 parts of astragalus, 30 parts of Chinese yam, 15 parts of plantain herb, 18 parts of pyrrosia lingua, 15 parts of sowthistle tasselflower herb, 10 parts of moutan bark, 24 parts of prepared rehmannia root, 15 parts of couch grass root, 15 parts of rhizoma alismatis and 7 parts of radix bupleuri. The drug properties of the selected raw medicinal materials supplement with one another, and mutual inhibition, mutual restraint and mutual detoxication of compatibility of medicines are avoided, so that the mutual promotion and mutual-assistance effects of the medicines are obvious, and the traditional Chinese medicine preparation has the effect of enhancing the immunity. The traditional Chinese medicine preparation has the effects of clearing heat and inducing diuresis, removing pathogenic heat from the blood and toxic material from the body and invigorating spleen and supplementing qi and is an oral pure traditional Chinese medicine preparation for treating acute nephritis.

Description

The Chinese medicine preparation for the treatment of acute nephritis
Technical field
The present invention relates to field of traditional Chinese, be specifically related to a kind of Chinese medicine preparation being used for the treatment of acute nephritis, there is effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, invigorating the spleen and benefiting QI.
Background technology
Acute nephritic syndrome (acute glomerulonephritis; Glomerulonephritis after infecting): a kind of Pathological is that in glomerule, diffuse inflammation sexually revises, and clinical manifestation is the hematuria of unexpected onset, red cell cast, mild proteinuria, and often with hypertension, edema and azotemia are the syndrome of feature.The foundation disease of acute nephritic syndrome can be caused to have: (1) infectious disease: to comprise antibacterial, disease that virus, parasite cause.(2) systemic disease: as systemic lupus erythematosus (sle), systemic vasculitis, anaphylactoid purpura, spontaneous cryoglobulinemia etc.(3) primary glomerulopathy: have membranoproliferative nephritis, IgA nephropathy, mesangial proliferative nephritis, focal segmental proliferative glomerulonephritis etc.(4) other: as serum sickness etc.Primary disease premorbid, has the streptococcal infection such as scarlet fever, tonsillitis history more, and morbidity in 7 ~ 21 days after infecting, three large symptoms below main manifestations: 1, edema: start, for the puffiness of the eyes, to develop into lower limb and anasarca after a few days, disappeared after 2 ~ 4 weeks.2, hematuria: majority is not good merchantable or brown.After about 2 weeks, gross hematuria disappears, hematuria sustainable several months during microscopy.3, hypertension: majority is that mild to moderate blood pressure raises, and performance headache, dizziness, vomiting etc., general lasting 2 weeks, then decline gradually.In addition, anemia, tired and lumbago etc. can also be accompanied.
Summary of the invention:
The object of the present invention is to provide a kind of Chinese medicine preparation being used for the treatment of acute nephritis, there is effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, invigorating the spleen and benefiting QI.
Present invention employs following technical scheme for achieving the above object: the medical material that Chinese medicine preparation of the present invention is selected and weight portion respectively: the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts.
In the raw material of Chinese medicine that the present invention selects: the Radix Astragali: have 1, an exterior deficiency spontaneous perspiration, be used for the weak caused spontaneous perspiration of body void table.2, night sweat due to yin deficiency; 3, acute nephritis edema, for the void edema caused by YANG QI deficiency; 4, oedema due to chronic nephritis, spleen person who suffer from deficiency of kidney Yang; 5, yang-energy is weak, caves in, have and promote diabrosis and limitation effect for skin infection not diabrosis for a long time.6, skin infection is burst for a long time and is not healed, and after skin infection diabrosis, does not close up for a long time, has the effect of promoting tissue regeneration and wound healing; 7, syndrome of deficiency of spleen qi, weak asthenia, has loose bowels, sinking of QI of middle-JIAO, and internal organs prolapse, the indigestion and loss of appetite all diseases of lack of appetite.8, syndrome of deficiency of lung qi.With the passing of time, shortness of breath and tired spirit, expectorant harmony brings up in lung is unable cough with asthma.9, hyperhidrosis and edema.10, weak for the deficiency of vital energy, fatigue and weakness, or sinking of QI of middle-JIAO, proctoptosis, uterine prolapse.Nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel; Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Rhizoma Dioscoreae: have and nourish strong, aid digestion, hold back sweating due to debility, effect of antidiarrheal, cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes are quenched one's thirst, oliguria frequently, road essence, women's leukorrhagia and dyspeptic chronic enteritis.Nature and flavor: sweet, flat, nontoxic.Gui Jing: return spleen, lung, kidney channel.Function: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Herba Plantaginis: function is applied: [nature and flavor] are sweet, cold.[return through] returns liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, removing heat from blood, removing toxic substances.Cure mainly accumulation of heat in the urinary bladder, dysuria, stranguria with turbid discharge leukorrhagia, heat-damp in summer dysentery, epistaxis, hematuria, liver-heat conjunctival congestion, laryngopharynx swelling and pain, carbuncle sore tumefacting virus.For pyretic stranguria, stranguria caused by urinary stone, stranguria with blood, hematuria, women leucorrhea, the diseases such as heat-damp in summer dysentery.In addition, Herba Plantaginis also controls phlegm-heat cough, hypertension, nephritis is shown in oliguria with red urine person, and gouty arthritis.
Folium Pyrrosiae: its nature and flavor are sweet, bitter, are slightly cold.Enter lung, urinary bladder channel; This kind medicinal, can clearing away damp-heat, diuresis are led to beautiful jade, controlled knife injury, scald, de-power is deficient.Function cures mainly: relieving stranguria by diuresis, and lung heat clearing expels the heat-evil.Control and drench pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, cough due to lung-heat, chronic tracheitis, incised wound, carbuncle.
Herba Emiliae: mildly bitter flavor, cool in nature.Function heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, removing heat from blood.Cure mainly upper respiratory tract infection, acute tonsillitis, oral ulcer, acute conjunctivitis, pneumonia, cholecystitis, infectious hepatitis, leptospirosis, acute appendicitis, pelvic inflammatory disease, orchitis, bacillary dysentery, enteritis, have blood in stool, the card such as urinary tract infection, nephritis.External fresh goods is smash deposited, dermatitis, eczema, traumatic injury swollen to carbuncle furuncle, has dissipating blood stasis for subsidence of swelling, an antipruritic effect of drawing out pus by applying a plaster to the affected part.
Cortex Moutan: effect: clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.Control blood deficiency overstrain dysphoria with feverish sensation in the chest palms and soles limbs pain head dusk center of gravity alarmed and panicky cheek red dryness of the mouth and throat heating night sweat and subtract food drowsiness and heat in blood is fought mutually, unsmooth menorrhea umbilicus abdominal distention and pain fever and chills similar to malaria; Control again unmarried girl's blood weak deficiency of YIN Rong Wei discord phlegmatic cough hectic fever human body weakness and emaciation.
Radix Rehmanniae Preparata: sweet in the mouth slightly warm in nature, returns liver, kidney channel, has nourishing the blood and yin, and effect of vital essence replenishing and marrow benifiting, is applicable to syndrome of deficiency of blood, menoxenia, syndrome of yin deficiency of liver and kidney, diabete, blood and essence asthenia card etc.Radix Rehmanniae Preparata is the important drugs of nourishing the liver and kidney, can not only nourishing the blood and yin, and can fill out marrow by spermatogenesis.Radix Rehmanniae Preparata has anti-lipid peroxidation, improves the effect such as activities of antioxidant enzymes, and can blood pressure lowering, blood fat reducing, inhibition thrombosis, improve myocardial ischemia etc.
Rhizoma Imperatae: nature and flavor: sweet-bitter flavor, cold in nature, nontoxic; Cure mainly: cooling blood for hemostasis, heat-clearing and toxic substances removing.For spitting blood, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, gastric heat is vomitted the sound of vomiting, coughs; Deficiency and coldness of spleen and stomach, the not thirsty person of frequent micturition avoids clothes.
Rhizoma Alismatis: nature and flavor: sweet, cold.Gui Jing: enter kidney, urinary bladder channel.Effect: diuretic, eliminating dampness by diuresis, expels the heat-evil.Control dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Chemical composition: tuber is containing rushing down alcohol (alisol) A, B, C, Alisol A monoacetate (alisol A monoacetate), Alisol B 23-monoacetate (alisol B monoacetate), alisol (epialisol) A shown by the mono-acetic acid vinegar of alisol C (alisol Cmonoacetate), Rhizoma Alismatis azulene alcohol (alismol), Rhizoma Alismatis azulene alcohol oxide (alismoxide), 16 'beta '-methoxy Alisol B 23-monoacetates (16 β-methocyal-isol Bmonoacetate), 16 beta-hydroxy Alisol B 23-monoacetates (16 β-hydroxyal-isol Bmonoacetate), sitosterol-3-O-stearyl-β-D-glucopyanoside (sitosterol-3-O-steroyl-β-D-glucopyranoside).Also containing choline (cho-line), the elements such as sugar and potassium, calcium, magnesium.
Radix Bupleuri: clearind deficient heat Chinese medicine, comes off for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus, menoxenia.Meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, lung meridian, spleen channel.Function: expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.
Raw medicinal material property of medicine effect selected by the present invention is complementary, has evaded the choosing of the mutual inhibition of compatibility between medicine, mutual restraint between two drugs, the mutual-detoxication, makes medicine mutual reinforcement between, mutual-assistance effect significantly, has the effect of enhancing immunity.Having effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, invigorating the spleen and benefiting QI, is for oral administration pure Chinese herbal medicine composition preparation for the treatment of acute nephritis.There is during clinical practice good precise effects.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.Such as these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; In order to make each raw material of this medicine play drug effect better, carry out special extraction for certain crude drug, as ethanol extraction, these can not be used for limiting the scope of the invention.
Medicine of the present invention has effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, invigorating the spleen and benefiting QI, is used for the treatment of acute nephritis.The present inventor through repeatedly studying, and passes through the checking repeatedly of clinical trial, finally have found the endo-medicine of better curative effect, thus completes the present invention.
Clinical test of pesticide effectiveness material and model case:
Open XX, man, 9 years old.2006 first visit dates JIUYUE 15 days.Patient starts pharyngalgia on August 20th, 2006, and fever with aversion to cold, examines as suppurative tonsillitis in certain children's hospital.Disappear through treatment pharyngalgia, body temperature is normal, but conscious unable.7 morning of JIUYUE, find facial edema, headache, pale complexion, lower limb are micro-swollen, indigestion and loss of appetite dry stool, and red urine is few, and the soreness of waist is stranded, red tongue, yellow and greasy fur, thready and rapid pulse, and this be the strongly fragrant lung of wind heat, the three burnt stagnation of QIs, and noxious dampness pents up under the pressure of blood system, suitable clearing away heat and cooling blood, lung qi dispersing dampness removing.Clothes we 6 doses, edema disappears, and six kinds of pulses is gentle, and defecation is logical adjusts.Take we 6 doses again with consolidate curative effect.
Method and effective dose: the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts; Get prescription ormal weight tcm and herbal slice, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
Decoction oral is main, and every day takes orally for 2 times sooner or later, each 150ml decoction being taken warmly.Decoction then acts on fast and power is high, is adapted to the more anxious severe one of the state of an illness.As lighter in the state of an illness or slow person, is preferably that pill is for oral administration asks its merit.
Detailed description of the invention
The described Chinese medicine preparation being used for the treatment of acute nephritis, it is characterized in that, the raw material of Chinese medicine of selection and weight portion respectively: the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts;
Preparation method: the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts; Make decoction pieces respectively, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.

Claims (1)

1. be used for the treatment of the Chinese medicine preparation of acute nephritis, it is characterized in that, the raw material of Chinese medicine of selection and weight portion respectively: the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts;
Its preparation method: get the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts; Make decoction pieces respectively, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
CN201410655585.0A 2014-11-03 2014-11-03 Traditional Chinese medicine preparation for treating acute nephritis Pending CN104383329A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108434412A (en) * 2017-02-14 2018-08-24 景金发 Kidney-nourishing toxin elimination and clot absorbing soup

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108434412A (en) * 2017-02-14 2018-08-24 景金发 Kidney-nourishing toxin elimination and clot absorbing soup

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Application publication date: 20150304