CN116747267A - Traditional Chinese medicine composition for promoting hair growth and preparation method thereof - Google Patents
Traditional Chinese medicine composition for promoting hair growth and preparation method thereof Download PDFInfo
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- CN116747267A CN116747267A CN202310940217.XA CN202310940217A CN116747267A CN 116747267 A CN116747267 A CN 116747267A CN 202310940217 A CN202310940217 A CN 202310940217A CN 116747267 A CN116747267 A CN 116747267A
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Abstract
The invention discloses a traditional Chinese medicine composition for promoting hair growth, which comprises 500 g-800 g of astragalus mongholicus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis; 300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae; 150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum herb and other traditional Chinese medicine compositions. The hair-growing traditional Chinese medicine composition comprises the components of polygonum multiflorum, biota orientalis, fructus psoraleae, rhizoma drynariae and the like, and the components of the traditional Chinese medicines can be mutually cooperated to tonify qi, activate blood and dredge channels; the hair follicle device can regulate the growth environment of hair, promote the blood circulation of the head, repair damaged hair follicle and promote the growth of new hair; can have good treatment effect on seborrheic alopecia; can reduce irritation of hair growth liquid to scalp, and reduce skin pathological symptoms such as rash, pustule, desquamation, urticaria, pruritus, pain, etc.
Description
Technical Field
The invention relates to the technical field of hair growth and health care, in particular to a traditional Chinese medicine composition for hair growth.
Background
Alopecia refers to the phenomenon of hair loss. The hair which is normally shed is the hair in the withdrawal phase and the resting phase, and the hair which enters the withdrawal phase and the hair which newly enters the growing phase are in dynamic balance continuously, so that the normal quantity of hair can be maintained. Pathological hair loss refers to abnormal or excessive loss of hair, which is responsible for a number of reasons.
There are two treatments for alopecia. The first method is hair transplantation, which is to transplant hair follicles of the scalp in a place where hair is still growing, to a place where hair is not growing, i.e., from the back to the front of the head. The second method is topical application, which is effective in preventing hair loss caused by various reasons, and promoting hair regeneration in bald or thin hair areas. Seborrheic alopecia often occurs in young and middle-aged people. The hair is bright, thin and thin, or dry, and has more dandruff, no luster, thin and thin hair.
In the course of hair loss and hair growth, traditional Chinese medicines or traditional Chinese medicine compositions are often used for treatment or auxiliary treatment. For example, the following are disclosed in Qianjin Fang: mulberry leaf and hemp leaf each gram. Boiling the medicine in rice wine water for a hundred times, and taking out the water bath for hair. The formula of the fleece-flower root for treating alopecia comprises the following components: polygonum multiflorum, biota orientalis, black sesame, eclipta alba, glossy privet fruit, dried rehmannia root, dried orange peel, pericarpium zanthoxyli, and dyers woad salt. Adding water ml, decocting to obtain a decoction, adding semen Sojae Atricolor g, decocting until the decoction is absorbed by beans, sun drying, chewing each time, and stopping healing every day. Formula for treating alopecia by gastrodia elata: gastrodia tuber, fleece-flower root, prepared rhizome of rehmannia, white paeony root, angelica, papaya, dodder seed and szechuan lovage rhizome. Grinding into powder, and making into honeyed pill, each pill g. The pill is taken in the morning and evening with warm water.
For example, CN202111194150.7 discloses a medicament for preventing alopecia and promoting hair growth and a preparation method thereof, and the specific preparation formula of the medicament for preventing alopecia and promoting hair growth comprises the following components: 2-3 parts of polygonum multiflorum, 3-4 parts of medlar, 2-3 parts of mulberry, 1-2 parts of angelica, 4-6 parts of red sage root, 2-4 parts of wild chrysanthemum flower, 3-5 parts of astragalus membranaceus, 3-5 parts of eclipta, 1-3 parts of prepared rehmannia root, 4-6 parts of dried ginger, 2-3 parts of Chinese honeylocust fruit, 3-4 parts of hairy antler, 3-5 parts of black sesame, 1-3 parts of walnut and 3-5 parts of rice straw ash liquid, more effective medicines for treating alopecia and promoting hair growth can be prepared, and when hair is washed, the medicines are directly mixed with water for washing hair, and the medicines are not required to be taken into the human body, so that side effects on the human body are reduced, and influence on the human body is avoided.
For example, CN201010156147.1 discloses a hair loss preventing agent, which is composed of the following substances: quinine sulfate: 2-4, linalool: 5-10, phenethyl alcohol: 4-6, cinnamyl alcohol: 1-3, geraniol: 3-6, glycerin: 30-40, rose oil: 30-40 parts of eugenol: 10-20, ethanol: 2300-2500, distilled water: 80 to 100. The invention has good use effect: can remarkably control alopecia, promote metabolism and circulation of hair, enhance vitality of hair, supplement nutrition, recover growth rate of hair, firm hair root, deep hair follicle to remove grease, inhibit sebaceous gland, and make hair regain growth, and feel cool when in use; has good curative effects on seborrheic alopecia, alopecia areata, mixed alopecia, postpartum alopecia and the like.
The prior art shows that the hair-growing related pharmaceutical preparation comprises oral administration and external administration, wherein the oral administration is mainly used for regulating the blood and the external administration is mainly used for directly acting on scalp hair follicles and the like, so that better hair-growing and hair-losing preventing effects are realized. As can be seen from statistics in the prior art, most hair-growing traditional Chinese medicine compositions comprise polygonum multiflorum, astragalus membranaceus, dried ginger, angelica sinensis, cinnamon, biota orientalis leaves, fructus psoraleae, rhizoma drynariae and the like; different Chinese medicinal compositions have different therapeutic effects.
However, the above-mentioned Chinese medicinal composition has a certain side effect, especially when it is externally applied. For example, astragalus may cause allergic reactions such as rashes, urticaria, etc.; the cinnamon powder can stimulate skin, and skin itching, rash and the like appear; the washing of the hair of the biota orientalis leaves can cause local itching and pain of scalp tissues, desquamation, toxic symptoms such as dizziness, headache and the like of partial patients after use, limb numbness, dyspnea, shock and the like. Contact dermatitis, such as skin color change, accompanied by itching, especially sun-like damage after sunlight irradiation, may occur after contact with fructus Psoraleae, and burning sensation and obvious pain sensation of local skin, also called phototoxic dermatitis, may be perceived. The Chinese angelica can achieve the whitening effect, but the skin is red, swollen and painful due to frequent or long-term use, even local pimple is possibly caused, and serious patients can also feel local burning.
In addition, some chemicals such as ethanol, dipotassium glycyrrhizinate, minoxidil and the like are usually added into the hair growth liquid, and the components have certain irritation, hair follicles are fragile, and the hair follicles can be damaged after long-term use, so that rash, pustule and pain symptoms can occur.
Therefore, the traditional Chinese medicine composition in the prior art has more careless anti-hair loss effect or hair growth effect, and has less attention to side effects such as pathological stimulation of scalp, rash, pustules, skin pain and the like; these disorders generally disappear automatically after cessation of the drug, but since hair growth is a long-term process, the scalp of the patient is likely to be in a pathological state for a long period of time during the course of treating hair loss.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for promoting hair growth and a preparation method thereof.
One of the objects of the present invention is:
how to reduce pathological stimulation of the anti-hair loss hair-growing traditional Chinese medicine composition preparation to scalp and reduce skin pathological symptoms such as scalp redness, rash, pustules and the like.
In order to achieve the above purpose, an embodiment of the invention provides a traditional Chinese medicine composition for promoting hair growth, which comprises the following traditional Chinese medicines in parts by weight:
500 g-800 g of astragalus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis;
300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae;
150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum;
130 g-220 g of ginseng leaf; 100 g-200 g of tomb head; 100 g-200 g of bitter orange;
50g to 100g of poria with hostwood.
In an optimized embodiment of the invention, the traditional Chinese medicine comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 360g of biota orientalis;
360g of prepared fleece flower root; 360g of fructus psoraleae; 360g of rhizoma drynariae;
180g of Chinese angelica; 180g of safflower; 180g of asarum;
180g of ginseng leaf; the tomb returns to 120g; 130g of bitter orange;
poria cocos wolf 60g.
In an optimized embodiment of the invention, the traditional Chinese medicine comprises the following traditional Chinese medicines in parts by weight:
550g of astragalus; 320g of cinnamon; 300g of biota orientalis;
310g of prepared fleece flower root; 360g of fructus psoraleae; 260g of rhizoma drynariae;
220g of Chinese angelica; 180g of safflower; 230g of asarum;
160g of ginseng leaf; 140g of tomb head; 150g of bitter orange;
50g of poria with hostwood.
Based on the traditional Chinese medicine composition, the invention discloses a preparation method of a traditional Chinese medicine composition for promoting hair growth, which comprises the following steps:
(1) The following traditional Chinese medicines in parts by weight are used as raw materials:
500 g-800 g of astragalus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis;
300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae;
150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum;
130 g-220 g of ginseng leaf; 100 g-200 g of tomb head; 100 g-200 g of bitter orange;
50g to 100g of poria with hostwood;
(2) The preparation method of the hair-growing tincture by using the raw materials comprises the following steps:
pulverizing various traditional Chinese medicines into coarse powder or slicing, adding ethanol solution with the mass fraction of 40% -50% for immersing, stirring and sealing, and immersing for 2-4 d; filtering to obtain filtrate, and decocting the residue in water; decocting, filtering, and mixing filtrates; boiling for 5-10 min, cooling, and fine filtering; adding glycerol accounting for 3-5% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growing tincture.
In an optimized embodiment of the invention, the raw materials in the preparation method comprise:
550g of astragalus; 320g of cinnamon; 300g of biota orientalis;
310g of prepared fleece flower root; 360g of fructus psoraleae; 260g of rhizoma drynariae;
220g of Chinese angelica; 180g of safflower; 230g of asarum;
160g of ginseng leaf; 140g of tomb head; 150g of bitter orange;
50g of poria with hostwood.
In summary, the invention has the following advantages:
1. the hair-growing traditional Chinese medicine composition comprises the components of polygonum multiflorum, biota orientalis, fructus psoraleae, rhizoma drynariae and the like, and the components of the traditional Chinese medicines can be mutually cooperated to tonify qi, activate blood and dredge channels; the hair follicle device can regulate the growth environment of hair, promote the blood circulation of the head, repair damaged hair follicle and promote the growth of new hair; can have good treatment effect on seborrheic alopecia.
2. The composition of the invention can reduce the irritation of the hair tonic to the scalp and reduce the occurrence of skin pathological symptoms such as rash, pustules, desquamation, urticaria, pruritus, pain and the like.
Detailed Description
The invention provides a traditional Chinese medicine composition for promoting hair growth, which comprises the following traditional Chinese medicines in parts by weight:
500 g-800 g of astragalus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis;
300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae;
150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum;
130 g-220 g of ginseng leaf; 100 g-200 g of tomb head; 100 g-200 g of bitter orange;
50g to 100g of poria with hostwood.
In one embodiment of the invention, the hair-growing traditional Chinese medicine composition comprises the following traditional Chinese medicines in parts by weight:
550g of astragalus; 320g of cinnamon; 300g of biota orientalis;
310g of prepared fleece flower root; 360g of fructus psoraleae; 260g of rhizoma drynariae;
220g of Chinese angelica; 180g of safflower; 230g of asarum;
160g of ginseng leaf; 140g of tomb head; 150g of bitter orange;
50g of poria with hostwood.
The invention discloses a preparation method of a traditional Chinese medicine composition for promoting hair growth, which comprises the following steps:
(1) The following traditional Chinese medicines in parts by weight are used as raw materials:
500 g-800 g of astragalus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis;
300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae;
150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum;
130 g-220 g of ginseng leaf; 100 g-200 g of tomb head; 100 g-200 g of bitter orange;
50g to 100g of poria with hostwood;
(2) The preparation method of the hair-growing tincture by using the raw materials comprises the following steps:
pulverizing various traditional Chinese medicines into coarse powder or slicing, adding ethanol solution with the mass fraction of 40% -50% for immersing, stirring and sealing, and immersing for 2-4 d; filtering to obtain filtrate, and decocting the residue in water; decocting, filtering, and mixing filtrates; boiling for 5-10 min, cooling, and fine filtering; adding glycerol accounting for 3-5% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growing tincture.
The traditional Chinese medicine composition is added with a plurality of traditional Chinese medicine components, the components are obtained according to the mutual synergistic compatibility principle of traditional Chinese medicines, and the proportion of the traditional Chinese medicine components can be properly adjusted according to actual conditions and applicable people.
Radix astragali; has effects of invigorating spleen, invigorating middle warmer, invigorating yang, consolidating superficial resistance, promoting urination, removing toxic substances, and promoting granulation. It is indicated for spleen qi deficiency, lung qi deficiency, spontaneous perspiration due to qi deficiency, qi and blood deficiency, and sores and ulcers, or chronic ulcer.
Cinnamon bark; has effects of warming middle-jiao, invigorating kidney, dispelling cold and relieving pain, and can be used for treating lumbago, knee cold pain, deficiency cold stomach pain, chronic dyspepsia, abdominal pain, emesis, diarrhea, cold-affected amenorrhea, etc.
Biota orientalis leaves; bitter and slightly cold, clear and purge, astringe and astringe, enter lung, liver, spleen and large intestine meridians. It is used for treating internal and traumatic hemorrhage by cooling blood, astringing and stopping bleeding, and is suitable for patients with blood heat by parching charcoal for patients with deficiency-cold; it is also indicated for cough and dyspnea due to lung heat with excessive phlegm because it can clear lung heat and resolve phlegm to relieve cough; it also has effects of clearing heat and cooling blood to promote hair growth and blackening hair, and can be used for treating alopecia due to blood heat and premature graying of beard and hair. The product mainly contains flavonoid components such as quercetin, kaempferol, etc.; contains volatile oil such as cypress brain, acetate pine oil, tannin, etc. Has effects of cooling blood, stopping bleeding, eliminating phlegm, relieving cough, promoting hair growth and blackening hair.
Polygonum multiflorum Thunb; it enters liver and kidney meridians and has different actions of making and growing. It is slightly warm in preparation, sweet and astringent in flavor, not greasy and not dry, good in tonifying liver and kidney, replenishing essence and blood, and blackening hair and beard, and is a tonic good herb for deficiency of essence and blood. It has the effects of relieving sore, swelling, scrofula, and constipation due to weakness, promoting the circulation of qi, and tonifying deficiency. The product contains anthraquinone compounds, and contains chrysophanol and emodin as main ingredients, lecithin, crude fat, etc. Has the functions of detoxicating, eliminating carbuncle, preventing malaria, and relaxing bowel.
Fructus Psoraleae; bitter and pungent and warm, dry, warm and astringent, enter the kidney and spleen meridians. Not only tonify kidney and strengthen yang, secure essence and reduce urine, absorb qi and relieve asthma, but also treat impotence due to kidney deficiency, spermatorrhea and spermatorrhea, and asthma due to kidney deficiency; it is also the key herb for diarrhea due to spleen-kidney yang deficiency. The name "paper breaking person" is the harmony of its nominal name. The product contains coumarin such as psoralen and isopsoralen, flavonoid such as astragaloside, and monoterpene phenol such as bakuchiol. It also contains stigmasterol, sitosterol, glucoside, raffinose, etc. Has effects of invigorating kidney, supporting yang, stopping nocturnal emission, reducing urination, warming spleen, relieving diarrhea, and relieving asthma.
Rhizoma drynariae; bitter in property and warm in property. It enters liver and kidney meridians. Mainly contains naringin, methyl eugenol, rhizoma Drynariae dihydroflavone glycoside, rhizoma Drynariae acid, sitosterol, protocatechuic acid, etc. Has effects in treating injury, relieving pain, invigorating kidney, and strengthening bone; the external use has the efficacy of dispelling wind and removing freckle.
Chinese angelica root; sweet and moist, pungent and warm in nature, it enters liver and heart meridians and spleen meridians. It is good at replenishing blood and activating blood, regulating menstruation and relieving pain, relaxing bowel and expelling cold, and is suitable for treating constipation due to blood deficiency and blood stasis, especially constipation due to dryness of the intestines, and is not only a key herb for regulating menstruation in gynecology but also a good blood-replenishing product in internal medicine and is commonly used for detumescence and wound therapy in surgery. Mainly contains volatile oils such as ligustilide, angelicanone, carvacrol, n-butene furolactone, verbenone, safrole, etc., organic acid components such as ferulic acid, vanillic acid, nicotinic acid, succinic acid, etc., and components such as angelica polysaccharide, amino acid, vitamin A, etc.
Safflower; can be used for treating amenorrhea, dysmenorrhea, lochia, abdominal mass, chest pain, abdominal pain due to stagnation, chest and hypochondrium stabbing pain, traumatic injury, and pyocutaneous disease swelling and pain.
Herba asari; pungent and warm in property. It enters heart, lung and kidney meridians. Asarum has strong fragrance, is pungent and warm, enters heart, lung and kidney meridians, passes through the upper and lower parts of the body surface, has small toxicity and has stronger force. It is good at dispelling wind and cold, inducing resuscitation and relieving pain, and is a good herb for treating all pains and nasal obstruction and headache caused by wind-cold and wind-dampness. Has the effects of warming and dispersing lung cold and resolving phlegm and fluid retention, and is an essential herb for cold retention and lung retention. It is most suitable for headache due to shaoyin, nasosinusitis and toothache. The product contains lignan component, volatile oil, and trace amount of aristolochic acid I. Has effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, inducing resuscitation, warming lung, and resolving fluid retention.
Ginseng leaf; bitter and sweet in flavor, cold in nature, enter lung and stomach meridians. Mainly contains ginsenoside, kaempferol, ginseng flavone, etc. Has effects of invigorating qi, benefiting lung, dispelling summerheat, promoting fluid production, and can be used for treating cough due to qi deficiency, summer heat dysphoria, fluid consumption thirst, dizziness, and tiredness.
Returning the tomb head; is root of Patrinia scabiosaefolia or Patrinia scabiosaefolia belonging to Patriniaceae. Bitter and slightly sour, cool in nature. It enters heart and liver meridians. Has effects of eliminating dampness, stopping leukorrhagia, astringing, stopping bleeding, and clearing away heat and toxic materials. Can be used for treating leucorrhea with red and white discharge, metrorrhagia, diarrhea, dysentery, jaundice, malaria, intestinal abscess, pyocutaneous disease, traumatic injury, cervical cancer, and gastric cancer.
Bitter orange flower; pungent, sweet, slightly bitter and neutral in nature. Has effects of regulating qi-flowing, relieving chest stuffiness, regulating stomach function, and relieving vomiting. It is often used for chest oppression, abdominal distention and pain, poor appetite, nausea and vomiting.
Poria with Indian bread with wood, and its name. Is the root of pine in the middle of the sclerotium of the Polyporaceae fungus Poria cocos (Schw.) Cocos. Has effects of suppressing hyperactive liver and tranquillizing. Can be used for treating palpitation, amnesia, apoplexy, aphasia, tinea pedis, and tendons.
Example 1:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 360g of biota orientalis;
360g of prepared fleece flower root; 360g of fructus psoraleae; 360g of rhizoma drynariae;
180g of Chinese angelica; 180g of safflower; 180g of asarum;
180g of ginseng leaf; the tomb returns to 120g; 130g of bitter orange; poria cocos wolf 60g.
The preparation method of the hair-growing traditional Chinese medicine composition comprises the following steps:
(1) Preparing traditional Chinese medicine raw materials according to a formula;
(2) Pulverizing various Chinese medicinal materials into coarse powder or slicing, adding 40% ethanol solution, soaking, stirring, sealing, and soaking for 3d; filtering to obtain filtrate, decocting the residue in water at a weight ratio of water to residue of 3:1, filtering after decoction, and mixing filtrates; boiling for 6min, cooling, and fine filtering; adding glycerol accounting for 4% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growth tincture.
Example 2:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
550g of astragalus; 320g of cinnamon; 300g of biota orientalis;
310g of prepared fleece flower root; 360g of fructus psoraleae; 260g of rhizoma drynariae;
220g of Chinese angelica; 180g of safflower; 230g of asarum;
160g of ginseng leaf; 140g of tomb head; 150g of bitter orange; 50g of poria with hostwood.
The preparation method of the hair-growing traditional Chinese medicine composition comprises the following steps:
(1) Preparing traditional Chinese medicine raw materials according to a formula;
(2) Pulverizing various Chinese medicinal materials into coarse powder or slicing, adding 40% ethanol solution, soaking, stirring, sealing, and soaking for 3d; filtering to obtain filtrate, decocting the residue in water at a weight ratio of water to residue of 3:1, filtering after decoction, and mixing filtrates; boiling for 6min, cooling, and fine filtering; adding glycerol accounting for 4% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growth tincture.
Example 3:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
520g of astragalus; 310g of cinnamon; 320g of biota orientalis;
330g of prepared fleece flower root; 350g of fructus psoraleae; 280g of rhizoma drynariae;
230g of Chinese angelica; 160g of safflower; 220g of asarum;
180g of ginseng leaf; 150g of tomb head; 160g of bitter orange; poria cocos wolf 60g.
The preparation method of the hair-growing traditional Chinese medicine composition comprises the following steps:
(1) Preparing traditional Chinese medicine raw materials according to a formula;
(2) Pulverizing various Chinese medicinal materials into coarse powder or slicing, adding 40% ethanol solution, soaking, stirring, sealing, and soaking for 3d; filtering to obtain filtrate, decocting the residue in water at a weight ratio of water to residue of 3:1, filtering after decoction, and mixing filtrates; boiling for 5min, cooling, and fine filtering; adding glycerol with the mass of 5% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growing tincture.
Example 4:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
580g of astragalus; 350g of cinnamon; 320g of biota orientalis;
260g of prepared fleece flower root; 290g of fructus psoraleae; 230g of rhizoma drynariae;
200g of Chinese angelica; 200g of safflower; 250g of asarum;
180g of ginseng leaf; the tomb returns to 120g; 160g of bitter orange; 70g of poria with hostwood.
The preparation method of the hair-growing traditional Chinese medicine composition comprises the following steps:
(1) Preparing traditional Chinese medicine raw materials according to a formula;
(2) Pulverizing various Chinese medicinal materials into coarse powder or slicing, adding 40% ethanol solution, soaking, stirring, sealing, and soaking for 3d; filtering to obtain filtrate, decocting the residue in water at a weight ratio of water to residue of 3:1, filtering after decoction, and mixing filtrates; boiling for 6min, cooling, and fine filtering; adding glycerol accounting for 4% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growth tincture.
Example 5:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 260g of cacumen biotae;
280g of prepared fleece flower root; 320g of fructus psoraleae; 230g of rhizoma drynariae;
210g of Chinese angelica; 220g of safflower; 240g of asarum;
180g of ginseng leaf; 160g of tomb head; 160g of bitter orange; poria cocos wolf wood 90g.
The preparation method of the hair-growing traditional Chinese medicine composition comprises the following steps:
(1) Preparing traditional Chinese medicine raw materials according to a formula;
(2) Pulverizing various Chinese medicinal materials into coarse powder or slicing, adding 40% ethanol solution, soaking, stirring, sealing, and soaking for 3d; filtering to obtain filtrate, decocting the residue in water at a weight ratio of water to residue of 3:1, filtering after decoction, and mixing filtrates; boiling for 6min, cooling, and fine filtering; adding glycerol accounting for 4% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growth tincture.
Experimental example one: hair growth effect experiment
(1) The experiment records 90 patients with male 60 and female 30; the patients are patients with alopecia areata and hair rarefaction between 35 and 50 years old. All patients were divided into five groups of 30 individuals each, 20 men and 10 women. The first group was treated with the example 1 drug, the second group was treated with the example 2 drug, and the third group was treated with the example 3 drug.
(2) All patients were cleaned before using the drugs, and the hair density of the patients was measured after drying the hair; the hair density is the total number of hairs per square centimeter. Selecting a region with more serious alopecia from the alopecia areata or the alopecia area of the patient as a marked region; the detection part is marked, and the marked area or the detection part is detected every time. The location of the marker region detected by each patient may be different, but the area of the marker region of each patient at each location is the same; the hair density of the patient can be obtained after each test is completed. The average hair density for each group is the ratio of the sum of the hair density values for all patients in that group to the number of people, i.e. the average hair density is obtained.
(3) Each patient uses the hair tonic tincture of the invention to smear 2 times a day, uses about 10ml of the hair tonic tincture each time to smear, massages for 3-5min after smearing, uses for 2 months continuously, detects the hair density after 2 months, calculates the average hair density before treatment and the average hair density after 2 months of treatment of each group or each corresponding example. The hair-growing effect of the hair-growing tincture of the invention is detected by comparing the hair density of patients before the patients are smeared with the medicine, and the specific hair-growing effect is shown as follows.
| Group of | Average hair density before treatment | Average hair density after 2 months |
| Example 1 | 76±6 | 103±10 |
| Example 2 | 65±8 | 91±6 |
| Example 3 | 87±12 | 122±12 |
| Example 4 | 59±6 | 76±8 |
From the above, it can be seen that the hair growing tincture of the invention can remarkably increase the hair quantity after being used for a period of time, and the hair loss trace is reduced after being used, the hair follicle is healthy, and the oil control effect is ideal from the aspect of on-site use.
Experimental example two: effect of hair growth tincture on skin care
(A1) 200 patients with alopecia areata and alopecia and sparse hair between 35 and 50 years old are recorded in the experiment; all patients were divided into 5 groups of 40 persons each. Each group of patients was treated with the same drug, and the specific dosing for each group was as follows:
experiment group a:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 360g of biota orientalis;
360g of prepared fleece flower root; 360g of fructus psoraleae; 360g of rhizoma drynariae;
180g of Chinese angelica; 180g of safflower; 180g of asarum;
180g of ginseng leaf; the tomb returns to 120g; 130g of bitter orange; poria cocos wolf 60g.
The preparation method of the hair-growing traditional Chinese medicine composition comprises the following steps:
(1) Preparing traditional Chinese medicine raw materials according to a formula;
(2) Pulverizing various Chinese medicinal materials into coarse powder or slicing, adding 40% ethanol solution, soaking, stirring, sealing, and soaking for 3d; filtering to obtain filtrate, decocting the residue in water at a weight ratio of water to residue of 3:1, filtering after decoction, and mixing filtrates; boiling for 6min, cooling, and fine filtering; adding glycerol accounting for 4% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growth tincture.
I.e. the first group employed the traditional Chinese medicine composition of example 1.
Control group 1:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 360g of biota orientalis;
360g of prepared fleece flower root; 360g of fructus psoraleae; 360g of rhizoma drynariae;
180g of Chinese angelica; 180g of safflower; 180g of asarum; 180g of ginseng leaf.
Compared with the first group, the weight of the tomb-rhizome of Chinese tomb is reduced by 120g, the weight of bitter orange is reduced by 130g, and the weight of the Indian bread with pine is reduced by 60g.
Control group 2:
the traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 360g of biota orientalis;
360g of prepared fleece flower root; 360g of fructus psoraleae; 360g of rhizoma drynariae;
180g of Chinese angelica; 180g of safflower; 180g of asarum; 180g of ginseng leaf; poria cocos wolf 60g.
Compared with the first group, the number of tomb returns is 120g, and the number of bitter orange flowers is 130g.
Control group 3
600g of astragalus; 360g of cinnamon; 360g of biota orientalis; 360g of prepared fleece flower root; 360g of fructus psoraleae;
360g of rhizoma drynariae; 180g of Chinese angelica; 180g of safflower; 180g of asarum;
180g of ginseng leaf; 50g of red sage root and 50g of camellia seed.
Compared with the first group, 120g of tomb-rhizome of Chinese tomb, 130g of bitter orange and 60g of poria with hostwood are reduced; 50g of red sage root and 50g of camellia seed are added.
Control group 4:
quinine sulfate: 2-4, linalool: 5-10, phenethyl alcohol: 4-6, cinnamyl alcohol: 1-3, geraniol: 3-6, glycerin: 30-40, rose oil: 30-40 parts of eugenol: 10-20, ethanol: 2300-2500, distilled water: 80 to 100. Control group 4 is a chemical type of hair tonic.
(A2) Each patient uses the hair-growing product to smear every day, the times are 2 times a day, and massage is carried out for 5min after each smearing; continuously using for 2 weeks, and checking whether the head skin of the patient has pathological symptoms including red swelling, rash, pustule, pain, desquamation and the like; the number of people who developed pathological symptoms in each group was recorded.
(A3) Results of scalp test on patients after each group of hair tonic products
| Group of | Mild symptoms | Moderate symptoms | Severe symptoms | Symptomatic aggregate | Asymptomatic condition |
| Experimental group A | 2 | 1 | 0 | 3 | 37 |
| Control group 1 | 5 | 3 | 1 | 9 | 31 |
| Control group 2 | 7 | 4 | 0 | 11 | 29 |
| Control group 3 | 6 | 3 | 1 | 10 | 30 |
| Control group 4 | 11 | 5 | 2 | 18 | 22 |
From the above experiments, the experiment group A has the most asymptomatic population of the hair growth tincture and the control group 4 has the least asymptomatic population, which indicates that the pharmaceutical composition corresponding to the embodiment 1 of the invention has the least stimulation to the skin, has milder use experience, is not easy to cause pathological problems of the skin, reduces the side effects of the scalp after using the medicament, and has good long-term safety, namely, the pharmaceutical composition still has no adverse effect on the scalp of a human body under the long-term use condition.
Claims (5)
1. A traditional Chinese medicine composition for promoting hair growth comprises the following traditional Chinese medicines in parts by weight:
500 g-800 g of astragalus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis;
300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae;
150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum;
130 g-220 g of ginseng leaf; 100 g-200 g of tomb head; 100 g-200 g of bitter orange;
50g to 100g of poria with hostwood.
2. The hair growth traditional Chinese medicine composition according to claim 1, wherein: the traditional Chinese medicine comprises the following traditional Chinese medicines in parts by weight:
600g of astragalus; 360g of cinnamon; 360g of biota orientalis;
360g of prepared fleece flower root; 360g of fructus psoraleae; 360g of rhizoma drynariae;
180g of Chinese angelica; 180g of safflower; 180g of asarum;
180g of ginseng leaf; the tomb returns to 120g; 130g of bitter orange;
poria cocos wolf 60g.
3. The hair growth traditional Chinese medicine composition according to claim 1, wherein: the traditional Chinese medicine comprises the following traditional Chinese medicines in parts by weight:
550g of astragalus; 320g of cinnamon; 300g of biota orientalis;
310g of prepared fleece flower root; 360g of fructus psoraleae; 260g of rhizoma drynariae;
220g of Chinese angelica; 180g of safflower; 230g of asarum;
160g of ginseng leaf; 140g of tomb head; 150g of bitter orange;
50g of poria with hostwood.
4. The preparation method of the traditional Chinese medicine composition for promoting hair growth is characterized by comprising the following steps of:
(1) The following traditional Chinese medicines in parts by weight are used as raw materials:
500 g-800 g of astragalus; 300 g-400 g of cinnamon; 300g to 500g of biota orientalis;
300 g-400 g of prepared fleece flower root; 300 g-450 g of fructus psoraleae; 200 g-400 g of rhizoma drynariae;
150g to 350g of angelica; 100 g-250 g of safflower; 120 g-260 g of asarum;
130 g-220 g of ginseng leaf; 100 g-200 g of tomb head; 100 g-200 g of bitter orange;
50g to 100g of poria with hostwood;
(2) The preparation method of the hair-growing tincture by using the raw materials comprises the following steps:
pulverizing various traditional Chinese medicines into coarse powder or slicing, adding ethanol solution with the mass fraction of 40% -50% for immersing, stirring and sealing, and immersing for 2-4 d; filtering to obtain filtrate, and decocting the residue in water; decocting, filtering, and mixing filtrates; boiling for 5-10 min, cooling, and fine filtering; adding glycerol accounting for 3-5% of the filtrate after fine filtration, stirring uniformly, and filtering to obtain the hair growing tincture.
5. The method of manufacturing according to claim 4, wherein the raw materials include:
550g of astragalus; 320g of cinnamon; 300g of biota orientalis;
310g of prepared fleece flower root; 360g of fructus psoraleae; 260g of rhizoma drynariae;
220g of Chinese angelica; 180g of safflower; 230g of asarum;
160g of ginseng leaf; 140g of tomb head; 150g of bitter orange;
50g of poria with hostwood.
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