CN116547381A - 液体酶制剂 - Google Patents

液体酶制剂 Download PDF

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Publication number
CN116547381A
CN116547381A CN202180080379.XA CN202180080379A CN116547381A CN 116547381 A CN116547381 A CN 116547381A CN 202180080379 A CN202180080379 A CN 202180080379A CN 116547381 A CN116547381 A CN 116547381A
Authority
CN
China
Prior art keywords
enzyme preparation
liquid enzyme
protein
sorbitol
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180080379.XA
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English (en)
Chinese (zh)
Inventor
乘船沙纪
田中裕介
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amano Enzyme Inc
Original Assignee
Amano Enzyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amano Enzyme Inc filed Critical Amano Enzyme Inc
Publication of CN116547381A publication Critical patent/CN116547381A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01044—Protein-glutamine glutaminase (3.5.1.44)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
CN202180080379.XA 2020-12-04 2021-12-02 液体酶制剂 Pending CN116547381A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-201413 2020-12-04
JP2020201413 2020-12-04
PCT/JP2021/044245 WO2022118914A1 (ja) 2020-12-04 2021-12-02 液体酵素製剤

Publications (1)

Publication Number Publication Date
CN116547381A true CN116547381A (zh) 2023-08-04

Family

ID=81853924

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180080379.XA Pending CN116547381A (zh) 2020-12-04 2021-12-02 液体酶制剂

Country Status (5)

Country Link
US (1) US20240026332A1 (https=)
EP (1) EP4257682A4 (https=)
JP (1) JP7829496B2 (https=)
CN (1) CN116547381A (https=)
WO (1) WO2022118914A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120536416A (zh) * 2025-06-19 2025-08-26 四川大学 提高液体酸性蛋白酶稳定性的方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024303157A1 (en) * 2023-06-14 2026-01-08 Amano Enzyme Inc. Liquid enzyme preparation
CN121620590A (zh) 2023-09-01 2026-03-06 诺维信公司 稳定的液体脱酰胺酶组合物
WO2025233391A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
WO2025233389A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) * 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3281368B2 (ja) * 1990-11-30 2002-05-13 味の素株式会社 安定化トランスグルタミナーゼ組成物及び保存法
JP3609648B2 (ja) 1998-06-04 2005-01-12 天野エンザイム株式会社 新規蛋白質脱アミド酵素、それをコードする遺伝子、その製造法並びにその用途
EP1106696B1 (en) 1999-12-03 2005-07-06 Amano Enzyme Inc. Protein-deamidating enzyme, microorganism producing the same, gene encoding the same, production process therefor, and use thereof
CN101098626B (zh) 2005-01-13 2012-12-12 味之素株式会社 乳制品及其制备方法
CN101605532A (zh) * 2007-02-16 2009-12-16 惠氏公司 含有山梨糖醇的蛋白质调配物
DK2351837T3 (da) * 2008-09-09 2019-05-13 Amano Enzyme Inc Fremgangsmåde til at designe mutant enzym, fremgangsmåde til at fremstille mutant enzym og mutant enzym
FI126442B (en) * 2011-11-01 2016-12-15 Valio Oy Liquid enzyme preparation and process for its preparation
EP3130671B1 (en) 2014-03-07 2019-04-24 Ajinomoto Co., Inc. New protein deamidase
CN105796507B (zh) * 2014-12-29 2019-01-18 江苏众红生物工程创药研究院有限公司 含聚乙二醇化门冬酰胺酶的药物组合物及其制备方法
CN107326019B (zh) * 2016-02-16 2018-05-01 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
CN107693796B (zh) * 2016-06-22 2020-12-22 江苏众红生物工程创药研究院有限公司 Peg定点修饰的门冬酰胺酶注射剂
EP3680330A4 (en) * 2017-09-07 2021-09-01 Amano Enzyme Inc. STABILIZED DRY PROTEIN EMIDASE COMPOSITION
AU2024303157A1 (en) * 2023-06-14 2026-01-08 Amano Enzyme Inc. Liquid enzyme preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120536416A (zh) * 2025-06-19 2025-08-26 四川大学 提高液体酸性蛋白酶稳定性的方法

Also Published As

Publication number Publication date
EP4257682A4 (en) 2024-11-13
US20240026332A1 (en) 2024-01-25
WO2022118914A1 (ja) 2022-06-09
JPWO2022118914A1 (https=) 2022-06-09
EP4257682A1 (en) 2023-10-11
JP7829496B2 (ja) 2026-03-13

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