JP7829496B2 - 液体酵素製剤 - Google Patents

液体酵素製剤

Info

Publication number
JP7829496B2
JP7829496B2 JP2022566974A JP2022566974A JP7829496B2 JP 7829496 B2 JP7829496 B2 JP 7829496B2 JP 2022566974 A JP2022566974 A JP 2022566974A JP 2022566974 A JP2022566974 A JP 2022566974A JP 7829496 B2 JP7829496 B2 JP 7829496B2
Authority
JP
Japan
Prior art keywords
liquid enzyme
protein
enzyme preparation
sorbitol
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022566974A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022118914A1 (https=
Inventor
沙紀 乘船
裕介 田中
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amano Enzyme Inc
Original Assignee
Amano Enzyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amano Enzyme Inc filed Critical Amano Enzyme Inc
Publication of JPWO2022118914A1 publication Critical patent/JPWO2022118914A1/ja
Application granted granted Critical
Publication of JP7829496B2 publication Critical patent/JP7829496B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01044—Protein-glutamine glutaminase (3.5.1.44)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2022566974A 2020-12-04 2021-12-02 液体酵素製剤 Active JP7829496B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020201413 2020-12-04
JP2020201413 2020-12-04
PCT/JP2021/044245 WO2022118914A1 (ja) 2020-12-04 2021-12-02 液体酵素製剤

Publications (2)

Publication Number Publication Date
JPWO2022118914A1 JPWO2022118914A1 (https=) 2022-06-09
JP7829496B2 true JP7829496B2 (ja) 2026-03-13

Family

ID=81853924

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022566974A Active JP7829496B2 (ja) 2020-12-04 2021-12-02 液体酵素製剤

Country Status (5)

Country Link
US (1) US20240026332A1 (https=)
EP (1) EP4257682A4 (https=)
JP (1) JP7829496B2 (https=)
CN (1) CN116547381A (https=)
WO (1) WO2022118914A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024303157A1 (en) * 2023-06-14 2026-01-08 Amano Enzyme Inc. Liquid enzyme preparation
CN121620590A (zh) 2023-09-01 2026-03-06 诺维信公司 稳定的液体脱酰胺酶组合物
WO2025233391A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
WO2025233389A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) * 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions
CN120536416A (zh) * 2025-06-19 2025-08-26 四川大学 提高液体酸性蛋白酶稳定性的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010029685A1 (ja) 2008-09-09 2010-03-18 天野エンザイム株式会社 変異型酵素の設計法、調製法、及び変異型酵素
WO2013064736A1 (en) 2011-11-01 2013-05-10 Valio Ltd A liquid enzyme formulation and a process for its preparation
WO2024257876A1 (ja) 2023-06-14 2024-12-19 天野エンザイム株式会社 液体酵素製剤

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3281368B2 (ja) * 1990-11-30 2002-05-13 味の素株式会社 安定化トランスグルタミナーゼ組成物及び保存法
JP3609648B2 (ja) 1998-06-04 2005-01-12 天野エンザイム株式会社 新規蛋白質脱アミド酵素、それをコードする遺伝子、その製造法並びにその用途
EP1106696B1 (en) 1999-12-03 2005-07-06 Amano Enzyme Inc. Protein-deamidating enzyme, microorganism producing the same, gene encoding the same, production process therefor, and use thereof
CN101098626B (zh) 2005-01-13 2012-12-12 味之素株式会社 乳制品及其制备方法
CN101605532A (zh) * 2007-02-16 2009-12-16 惠氏公司 含有山梨糖醇的蛋白质调配物
EP3130671B1 (en) 2014-03-07 2019-04-24 Ajinomoto Co., Inc. New protein deamidase
CN105796507B (zh) * 2014-12-29 2019-01-18 江苏众红生物工程创药研究院有限公司 含聚乙二醇化门冬酰胺酶的药物组合物及其制备方法
CN107326019B (zh) * 2016-02-16 2018-05-01 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
CN107693796B (zh) * 2016-06-22 2020-12-22 江苏众红生物工程创药研究院有限公司 Peg定点修饰的门冬酰胺酶注射剂
EP3680330A4 (en) * 2017-09-07 2021-09-01 Amano Enzyme Inc. STABILIZED DRY PROTEIN EMIDASE COMPOSITION

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010029685A1 (ja) 2008-09-09 2010-03-18 天野エンザイム株式会社 変異型酵素の設計法、調製法、及び変異型酵素
WO2013064736A1 (en) 2011-11-01 2013-05-10 Valio Ltd A liquid enzyme formulation and a process for its preparation
WO2024257876A1 (ja) 2023-06-14 2024-12-19 天野エンザイム株式会社 液体酵素製剤

Also Published As

Publication number Publication date
EP4257682A4 (en) 2024-11-13
US20240026332A1 (en) 2024-01-25
WO2022118914A1 (ja) 2022-06-09
CN116547381A (zh) 2023-08-04
JPWO2022118914A1 (https=) 2022-06-09
EP4257682A1 (en) 2023-10-11

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