CN1165288C - 洗涤组合物 - Google Patents
洗涤组合物 Download PDFInfo
- Publication number
- CN1165288C CN1165288C CNB998160431A CN99816043A CN1165288C CN 1165288 C CN1165288 C CN 1165288C CN B998160431 A CNB998160431 A CN B998160431A CN 99816043 A CN99816043 A CN 99816043A CN 1165288 C CN1165288 C CN 1165288C
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- CN
- China
- Prior art keywords
- cationic
- polymer
- hair
- cleaning compositions
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Abstract
洗涤组合物，其中在含水载体中包含：a) 至少一种选自阴离子表面活性剂、加以改变而具有负电荷的两性表面活性剂、和它们的混合物的去污表面活性剂，和b)具有吸附在其上面的阳离子沉积聚合物的悬浮颗粒剂；其中吸附在悬浮颗粒剂上面的阳离子聚合物的比例占组合物中存在的阳离子聚合物总重量的至少5%。
Description
发明领域
本发明涉及洗涤组合物。更具体地说，本发明涉及含有阳离子聚合物和悬浮的微粒剂的洗涤组合物，所述组合物能增强悬浮的微粒剂的沉积和递送。这样的洗涤组合物包括洗发组合物或皮肤洗涤组合物，如洗发香波和调理剂、沐浴香波、淋浴凝胶、洗面组合物和泡沫浴液。
发明背景和现有技术
当颗粒剂通过掺入到冲洗组合物、一般是洗发香波和沐浴香波、调理剂等中来递送时，悬浮的微粒剂难以有效地沉积到表面，如皮肤或头发上。通常，这样的悬浮的微粒剂往往从欲沉积部位上被冲洗掉而不是沉积在该部位上。
已知阳离子沉积聚合物能加强香波和其它个人洗涤组合物中的某些组分的沉积。例如，US 5037818和US 5085857中描述了用阳离子瓜尔胶来加强抗微生物剂颗粒和不溶性硅氧烷各自的沉积。还有人建议用沉积聚合物来加强香波组合物中防晒物质的沉积。EP 386898中运用阳离子聚半乳甘露聚糖胶衍生物。WO 95/22311描述了使用某些阳离子聚丙烯酰胺聚合物来提高调理剂的沉积作用，所述调理剂包括硅氧烷、脂肪和油、蜡、烃、脂肪酸和脂肪醇、脂质、维生素和防晒剂。WO 97/48378涉及制备其中挥发性香料的沉积得以增强的个人液体清洗组合物的方法。该方法包括形成包含阳离子聚合物、挥发性香料和水的预混合物，然后将该预混合物加到含有阴离子表面活性剂的个人清洗基质组合物中。在该方法中，据信挥发性香料被物理性包埋到存在于组合物中的阳离子聚合物与阴离子表面活性剂之间形成的凝聚层或离子对内。
用阳离子辅助物质沉积有这样一个问题：虽然阳离子聚合物可以有效地辅助许多种物质的沉积(正如上述现有技术所述)，但是它们往往与其所要沉积的物质混合在一起。据认为这种混合是由于WO97/48378中所假定的那种物理包埋机制。这降低了它所要沉积成分(例如硅氧烷等调理剂)的沉积效率，并且由于过量积聚导致毛发干枯。
本发明者们发现这个问题可通过将阳离子聚合物预先吸附到所要沉积的特定悬浮的微粒剂上而得到解决。出人意料的是，这样形成的吸附物在表面活性剂存在下是稳定的。
发明概述
本发明提供洗涤组合物，其中在含水载体中包含：
1)至少一种选自阴离子表面活性剂、已加以改变而具有负电荷的两性表面活性剂、和它们的混合物的去污表面活性剂，和
2)具有吸附在其上面的阳离子沉积聚合物的悬浮的微粒剂；其中吸附在悬浮的微粒剂上面的阳离子聚合物的比例为占组合物中存在的阳离子聚合物总重量的至少5％。
另一方面，本发明提供了制备如上所定义的洗涤组合物的方法，所述方法包括以下步骤：
1)将阳离子沉积聚合物吸附到悬浮的微粒剂上，和
2)将所得吸附物与液体载体中含有至少一种上述去污表面活性剂的基质洗涤组合物混合。
发明详述与优选方案
(I)
去污表面活性剂
本发明洗涤组合物包含至少一种选自阴离子表面活性剂、已被加以改变而具有负电荷的两性表面活性剂、和它们的混合物的去污表面活性剂。
阴离子表面活性剂
适合用于本发明洗涤组合物的阴离子表面活性剂包括烷基硫酸盐、烷基醚硫酸盐、烷芳基磺酸盐、链烷酰基羟乙基磺酸盐、烷基琥珀酸盐、烷基磺基琥珀酸盐、N-烷酰基肌氨酸盐、烷基磷酸盐、烷基醚磷酸盐、烷基醚羧酸盐、α-烯烃磺酸盐、和酰基甲基牛磺酸盐，尤其是它们的钠盐、镁盐、铵盐、和一、二或三乙醇胺盐。烷基和酰基通常含有8-18个碳原子，并且可以是不饱和的。烷基醚硫酸盐、烷基醚磷酸盐和烷基醚羧酸盐可以每个分子含有1-10个氧化乙烯或氧化丙烯单元，优选每个分子含有2-3个氧化乙烯单元。
合适的阴离子表面活性剂的实例有十二烷基硫酸钠、月桂基醚硫酸钠、十二烷基磺基琥珀酸铵、十二烷基硫酸铵、月桂基醚硫酸铵、十二烷基苯磺酸钠、三乙醇胺十二烷基苯磺酸盐、椰油基羟乙基磺酸钠、月桂酰基羟乙基磺酸钠、和N-十二烷基肌氨酸钠。
两性表面活性剂
加以改变而具有负电荷的两性表面活性剂可以代替阴离子表面活性剂或与阴离子表面活性剂联合用于本发明洗涤组合物。两性表面活性剂的电荷可用传统方法加以改变，如通过调节含有两性表面活性剂的表面活性剂溶液的pH进行改变。
适合用于本发明洗涤组合物的两性表面活性剂包括烷基胺氧化物、烷基甜菜碱、烷基酰氨基丙基甜菜碱、烷基磺基甜菜碱、烷基甘氨酸盐、烷基羧基甘氨酸盐、烷基两性丙酸盐、烷基两性甘氨酸盐、和烷基酰氨基丙基羟基磺基甜菜碱。其实例包括十二基胺氧化物、椰油基二甲基磺基丙基甜菜碱、和优选的十二烷基甜菜碱、椰油酰氨基丙基甜菜碱和椰油两性丙酸钠。
阴离子或带负电荷的两性表面活性剂在本发明洗涤组合物中的含量为占组合物总重量的3-50％、优选3-30％、更优选5％-20％。
阴离子或带负电荷的两性表面活性剂可与其它天然或合成辅助表面活性剂联合使用。任选的辅助表面活性剂一般选自非离子表面活性剂、两性表面活性剂、阳离子表面活性剂和它们的混合物。
还可以存在其它表面活性剂以用作本发明洗涤组合物的乳化组分，例如用作硅氧烷乳化颗粒的乳化剂。该表面活性剂可能与去污表面活性剂相同，也可能不同。
适合的乳化表面活性剂在本领域内是众所周知的，包括阴离子表面活性剂和非离子表面活性剂。用作硅氧烷颗粒之类物质的乳化剂的阴离子表面活性剂的实例有烷基芳基磺酸盐，例如十二烷基苯磺酸钠；烷基硫酸盐，例如十二烷基硫酸钠；烷基醚硫酸盐，例如月桂基醚硫酸钠nEO，其中n是1-20；烷基酚醚硫酸盐，例如辛基苯酚醚硫酸盐nEO，其中n为1-20；和磺基琥珀酸盐，例如二辛基磺基琥珀酸钠。
用作硅氧烷颗粒之类物质的乳化剂的非离子表面活性剂的实例有烷基酚乙氧基化物，例如壬基苯酚乙氧基化物nEO，其中n为1-50；醇乙氧基化物，例如月桂醇nEO，其中n为1-50；酯乙氧基化物，例如聚氧乙烯一硬脂酸酯，其中氧化乙烯单元的数目是1-30。
本发明洗涤组合物中表面活性剂的总含量占组合物总重量的3-50％、优选5-30％、更优选10％-25％。
(II)
悬浮的微粒剂
悬浮的微粒剂可适当地选自一种或多种下述种类的物质：
调理剂
本文所用术语“调理剂”包括能给头发和/或皮肤带来特别调理益处的任意物质。例如，在用于皮肤的洗涤组合物，如沐浴香波中，可使用诸如润湿剂、精油、防晒或晒后治疗物质、封闭油等物质。在用于头发的洗涤组合物，如洗发香波和调理剂中，适合的物质是有利于头发保持光泽、柔软、易于梳理、保持湿润、防止静电、不损头发、良好发质、可定型性、顺从性的物质。
用于本发明的优选调理剂，包括给头发赋予湿和干调理效果，如柔软、光滑和易于梳理的乳化硅氧烷。
在本发明中使用的制备硅氧烷颗粒乳液的各种方法都是可采用的，并且在本领域内是众所周知且有文献记载的。
硅氧烷自身(不是乳液或最终洗涤组合物)的粘度优选为10Pm·s(10000cps)-5000Pm·s(5百万cps)。粘度可按照Dow CorningCorporate CTM004，1970，7月20日进一步提出的测试方法，用玻璃毛细管粘度计来测量。
适合的硅氧烷包括聚二有机硅氧烷，尤其是CTFA命名为二甲硅油的聚二甲基硅氧烷。其实例是在25℃粘度最高0.1m2/s(100000厘沲)的二甲硅油液体，该二甲硅油可以作为Viscasil系列从GeneralElectric公司购得，和作为DC200系列从Dow Corning购得。
CTFA命名为氨基二甲硅油(amodimethicone)的含有氨基官能团的硅氧烷也适用于本发明组合物，CTFA命名为聚二甲基硅氧烷醇的具有羟基端基的聚二甲基硅氧烷亦如此。
硅橡胶纯胶料也是合适的。“硅橡胶纯胶料”指分子量为200000-1000000的聚二有机硅氧烷，其具体实例包括聚二甲基硅氧烷胶、聚二甲基硅氧烷醇胶、聚二甲基硅氧烷/二苯基/甲基乙烯基硅氧烷共聚物、和它们的混合物。其实例包括US 4152416(Spitzer)和“通用电气硅橡胶产品目录”SE30，SE33，SE54和SE76中所描述的那些物质。
轻度交联的硅橡胶纯胶料，例如WO96/31188所描述的硅橡胶纯胶料也适用于本发明。这些物质可以赋予头发良好发质、蓬松、可定型性、以及良好的湿和干调理性。
用于本发明洗涤组合物的优选乳化硅氧烷在洗涤组合物中具有低于30微米的平均硅氧烷粒径。可通过激光扫描技术，使用产自MalvernInstruments的2600D Particle Sizer来测量粒径。
在本发明洗涤组合物中，硅氧烷物质的平均粒径可以为2-30μm(微米)、优选2-20μm(微米)、更优选3-10μm(微米)。
此外，硅氧烷物质可以以小粒径、例如小于2μm(微米)的乳化颗粒形式存在于本发明洗涤组合物中。在某些情况下，降低粒径可改善调理效果。
平均硅氧烷粒径≤0.15μm(微米)的硅氧烷乳液通常称为微乳液。这种微乳化颗粒的粒径一般≤0.15μm(微米)、0.01-0.15μm(微米)更适合。因为它们能够配制具有高度稳定性和优良视觉效果，如半透明或透明制剂的洗涤组合物，所以这样的微乳化颗粒是有利的。
适用于本发明的硅氧烷乳液可以以预乳化形式商购获得。这是特别优选的，因为可通过简单的混合将预形成的乳液掺合到本发明洗涤组合物中。
预形成的乳液一般含有约50％的硅氧烷。预形成的乳液可从硅油供应商获得，如Dowing Corning，General Electric，Union Carbide，Wacker Chemie，Shin Etsu，Toshiba，Toyo Beauty Co，和ToraySilicone Co.。较大粒径硅氧烷乳液(乳液中平均粒径约为3-20μm(微米))的实例是由Dowing Corning销售的DC-1310，和Shin-Etsu销售的X-52-1086、X-52-2127和X-52-2112。
合适的较小粒径预形成乳液(乳液中平均粒径小于约2μm(微米))的实例包括乳液DC2-1766、DC2-1784、和微乳液DC2-1865与DC2-1870，它们都可从Dow Corning购得。它们都是聚二甲基硅氧烷醇的乳液/微乳液。交联硅橡胶纯胶料也可以以预乳化形式获得，这种形式便于配制。优选实例是从Dowing Corning购得的DC X2-1787，它是交联聚二甲基硅氧烷醇胶的乳液。还优选的实例是从DowingCorning购得的DC X2-1391，它是交联聚二甲基硅氧烷醇胶的微乳液。
掺合到本发明洗涤组合物中的硅氧烷的量取决于所要达到的调理水平和所用物质。优选含量为占组合物总重量的0.01-约10％，但是这些限度并不是绝对的。下限由达到调理的最低水平决定，上限由避免使头发或皮肤呈现不能接受的油腻感的最高水平决定。我们发现，占组合物总重量0.5-1.5％的硅氧烷量是特别合适的水平。
如果硅氧烷是以上述预形成乳液的形式加入，乳液的精确量当然就取决于乳液的浓度，并且应当选择使最终的组合物中含有所需量的不溶解、不挥发的硅氧烷。
更优选的一类调理剂是用于改善头发发质、蓬松性和可定型性的全烷(烯)基烃。
EP 567326和EP 498119中描述了赋予头发可定型性和提高头发发质的全烷(烯)基烃类物质。优选物质是以商品名PERMETHYL购自Presperse，Inc.的聚异丁烯物质。
掺合到本发明洗涤组合物中的全烷(烯)基烃类物质的量，取决于所要达到的发质和蓬松性改善水平以及所用的特定物质。优选的量为占组合物总重量的0.01-约10％，但这并不是绝对的。下限由达到发质和蓬松性改善效果的最低水平决定，上限由避免头发呈现不能接受的最高坚硬程度决定。我们发现，占组合物总重量0.5-2％的全烷(烯)基烃类物质的量是特别合适的水平。
固体活性剂
一般的固体活性剂的实例是杀微生物剂，例如吡啶硫酮(pyridinethione)的重金属盐，尤其是吡啶硫酮锌，其它杀微生物剂，例如是苯咪丁酮、羟甲辛吡酮、乙醇胺、二硫化硒和酮康唑。这些物质的平均粒径一般为约0.2-约50μm(微米)、优选为约0.4-约10μm(微米)。
当固体活性剂是抗菌剂时，例如吡啶硫酮锌，其用量以占组合物总重量的0.001％-约1％为宜。
其它合适的固体活性剂包括色素颗粒，例如适用于头发的固体染料或着色剂，以及金属胶体物。
美化剂
头发处理组合物如香波和调理剂通常是不透明或呈珠光色，以吸引消费者。
不透明剂的实例包括高级脂肪醇(如鲸蜡醇、硬脂醇、花生四烯醇和二十二烷醇)，固体酯(如棕榈酸鲸蜡酯、月桂酸甘油酯、硬脂酰胺MEA硬脂酸酯)，高分子量脂肪酰胺和链烷醇酰胺以及各种脂肪酸衍生物，如丙二醇和聚乙二醇酯。用于使头发处理组合物不透明的无机物包括硅酸镁铝、氧化锌和二氧化钛。
珠光剂在组合物中一般形成薄的小片型晶体，其作用就象很小的镜子。珠光剂产生珠光光泽效应。根据其所用的介质和所采用的条件，上面列出的有些不透明剂也可结晶成珠光剂。
代表性珠光剂可选自C16-C22脂肪酸(例如硬脂酸、肉豆蔻酸、油酸和二十二烷酸)，C16-C22脂肪酸与醇形成的酯，和掺入亚烷基二醇之类单元的C16-C22脂肪酸。合适的烷二醇单元可包括乙二醇和丙二醇。然而，也可使用具有较长亚烷基链的二醇。合适的具有较长亚烷基链的二醇包括聚乙二醇和聚丙二醇。
其实例有包含1-7个氧化乙烯单元的C16-C22脂肪酸的聚乙二醇单酯或二酯，以及C16-22脂肪酸的乙二醇酯。优选的酯包括聚乙二醇二硬脂酸酯和乙二醇二硬脂酸酯。市售聚乙二醇二硬脂酸酯的实例是EUPERLAN PK900(购自Henkel)或GENAPOL TS(购自Hoechst)。乙二醇二硬脂酸酯的一个实例是EUPERLAN PK3000(购自Henkel)。
其它珠光剂包括具有16-22个碳原子的脂肪酸链烷醇酰胺(例如硬脂酸一乙醇酰胺、硬脂酸二乙醇酰胺、硬脂酸一异丙醇酰胺和硬脂酸一乙醇酰胺硬脂酸酯)；长链脂肪酸的长链酯(例如硬脂酸硬脂醇酯、棕榈酸鲸蜡酯)；甘油酯(例如甘油二硬脂酸酯)，长链链烷醇酰胺的长链酯(例如硬脂酰胺DEA二硬脂酸酯、硬脂酰胺MEA硬脂酸酯)，和烷基(C18-C22)二甲基氧化胺(例如硬脂基二甲基氧化胺)。
其它合适的珠光剂包括无机物，如有基于天然矿物云母的真珠质色素。其实例是包覆有云母的二氧化钛。珠光剂粒径可以为2-150μm(微米)。小颗粒一般可呈现珍珠似外表，而平均粒径较大的颗粒使组合物闪光。
合适的包覆有云母的二氧化钛颗粒是以商标名TIMIRON(Merck)或FLAMENCO(Mearl)出售的产品。
不透明剂或珠光剂在本发明组合物中的含量一般为占组合物总重量的0.01-20％、优选0.01-5％、更优选0.02-2％。
(III)
阳离子沉积聚合物
“沉积聚合物”指的是这样的物质，在使用过程中，它促进本发明洗涤组合物的调理剂沉积到目的部位，即头发和/或头皮上。
阳离子沉积聚合物可以是一种均聚物或由两种或多种单体形成。这类聚合物的分子量一般为5000-10000000，通常至少10000，优选为100000-约2000000。这类聚合物具有含阳离子氮的基团，例如季铵或质子化氨基或它们的混合物。
含有阳离子氮的基团通常作为取代基存在于沉积聚合物的总单体单元一部分上。因此，如果这类聚合物不是均聚物，它可以含有非阳离子单体间隔单元。这样的聚合物在CTFA《化妆品成分词典》，第三版中有描述。对阳离子单体单元与非阳离子单体单元的比例加以选择，以获得阳离子电荷密度在所要求范围内的聚合物。
适合的阳离子沉积聚合物包括，例如具有阳离子胺或季铵官能团的乙烯基单体与水溶性间隔团单体的共聚物，所述间隔团单体有例如(甲基)丙烯酰胺、烷基和二烷基(甲基)丙烯酰胺、(甲基)丙烯酸烷基酯、乙烯基己内酯和乙烯基吡咯烷。烷基和二烷基取代的单体优选含有C1-C7烷基，更优选C1-3烷基。其它合适的间隔团包括乙烯基酯、乙烯基醇、马来酸酐、丙二醇和乙二醇。
根据胺的特定种类和组合物的pH值，阳离子胺可以是伯胺、仲胺或叔胺。仲胺和叔胺、尤其是叔胺是优选的。
可将胺取代的乙烯基单体和胺，以胺的形式聚合，然后通过季铵化作用转化成铵。
阳离子沉积聚合物可包含由胺和/或季铵取代的单体和/或相容间隔团单体衍生来的单体单元的混合物。
适合的阳离子沉积聚合物包括，例如：
-1-乙烯基-2-吡咯烷与1-乙烯基-3-甲基咪唑盐(如盐酸盐)的共聚物，在工业上，按照“化妆品、盥洗用品和香料协会”(CTFA)命名，该共聚物称为Polyquaternium-16。该物质可从BASF WyandotteCorp.(Parsippany，NJ，USA)以商品名LUVIQUAT(如LUVIQUATFC370)商购获得；
-1-乙烯基-2-吡咯烷和异丁烯酸二甲基氨基乙酯共聚物，在工业上(CTFA)称为Polyquaternium-11。该物质可从Gaf Corporation(Wayne，NJ，USA)以商品名GAFQUAT(如GAFQUAT 755N)商购获得；
-含有阳离子二烯丙基季铵的聚合物，包括例如二甲基二烯丙基氯化铵均聚物，和丙烯酰胺与二甲基二烯丙基氯化铵的共聚物，二者在工业上(CTFA)分别称为Polyquaternium 6和Polyquaternium7；
-具有3-5的碳原子的不饱和羧酸的均聚物和共聚物的氨基烷基酯的无机酸盐(如US 4009256中所述)；
-阳离子聚丙烯酰胺(如WO 95/22311中所述)。
其它可使用的阳离子沉积聚合物包括阳离子多糖聚合物，例如阳离子纤维素衍生物、阳离子淀粉衍生物和阳离子瓜尔胶衍生物。
适用于本发明组合物的阳离子多糖聚合物包括下式所示聚合物：
A-O-[R-N+(R1)(R2)(R3)X-]
其中：A是葡萄糖酐残基，例如淀粉或纤维素葡萄糖酐残基。R是亚烷基、氧亚烷基、聚氧亚烷基、或羟基亚烷基、或它们的组合，R1、R2和R3独立地代表烷基、芳基、烷芳基、芳烷基、烷氧基烷基、或烷氧基芳基，每一所述基团含有最高约18个碳原子。每一阳离子部分的碳原子总数目(即R1、R2和R3的碳原子总和)优选为约20或更少，X是阴离子抗衡离子。
阳离子纤维素可以从Amerchol Corp.(Edison，NJ，USA)，以其Polymer JR(商品名)和LR(商品名)系列聚合物之名，作为与三甲基铵取代的环氧化物反应而得到的羟乙基纤维素的盐商购获得，该物质在工业上(CTFA)称为Polyquaternium 10。另一种阳离子纤维素包括与月桂基二甲基铵取代的环氧化物反应而得到的羟乙基纤维素的聚合季铵盐，该物质在工业上(CTFA)称为Polyquaternium24。这些物质可从Amerchol Corp.(Edison，NJ，USA)以商品名PolymerLM-200获得。
其它适合的阳离子多糖聚合物包括含季氮的纤维素醚(如US3962418中所述)和醚化纤维素与淀粉的共聚物(如US 3958581中所述)。
尤其适合使用的阳离子多糖聚合物是阳离子瓜尔胶衍生物如瓜尔胶羟丙基氯化三铵(可以以JAGUAR商品名系列从Rhone-Poulenc商购获得)。
其实例有JAGUAR C13S，该物质具有低阳离子基团取代度和高粘度；JAGUAR C15，具有中等程度取代度和低粘度；JAGUAR C17(取代度高，高粘度)；JAGUAR C16，是含有低水平取代基及阳离子季铵的羟丙基化阳离子瓜尔胶衍生物；JAGUAR 162，是高度透明、中等粘度、并具有低取代度的瓜尔胶。
阳离子沉积聚合物优选选自阳离子纤维素和阳离子瓜尔胶衍生物。特别优选的沉积聚合物是JAGUAR C13S、JAGUAR C15、JAGUAR C17和JAGUAR C16以及JAGUAR C162。
吸附物
本发明的关键是将阳离子沉积聚合物吸附到悬浮的微粒剂上。本发明人发现，可形成这样的吸附物，在添加表面活性剂时它们具有令人惊奇的稳定性，并且当使用期间把洗涤组合物稀释时，能优先促进悬浮的微粒剂的沉积。
制备阳离子沉积聚合物与悬浮的微粒剂的吸附物的一种方便方法如下：
(I)制备阳离子沉积聚合物的水溶液；
(II)向所得溶液中加入悬浮的微粒剂；
(III)调节溶液的pH值，使阳离子沉积聚合物达到或接近其等电点，混合，然后再调节混合物的pH值，给阳离子沉积聚合物再充电。
术语“接近其等电点”一般指阳离子聚合物介于其等电点的1到1.5pH单位之间。等电点取决于所用的特定阳离子聚合物。
当在上述步骤(III)后再充电时，阳离子沉积聚合物的阳离子电荷密度(定义为每克聚合物的阳离子电荷摩尔数)一般为至少0.1meq/g、优选高于0.8或更高。阳离子电荷密度一般应不超过4meq/g，优选低于3、更优选低于2meq/g。电荷密度可用电导率测定法分析。
例如，优选的阳离子沉积聚合物是JAGUAR C13S，再充电后其阳离子电荷密度一般为约0.8meq/g。
按照如上所述的方法，对于JAGUAR C13S，我们发现可通过下述方法，用悬浮颗粒硅氧烷小滴形成特别耐久的吸附物：
(i)配制pH值高于8(优选约9)的JAGUAR C13S水溶液(以约1wt％为宜)；
(ii)加入硅氧烷小滴；
(iii)调节混合物的pH值至4-7(优选约6)，混合约20分钟，然后重新调节混合物的pH值至8以上(优选约9)。
洗涤组合物中阳离子沉积聚合物的总量通常为占组合物总重量的0.005-2％，优选0.01-1.0％，0.03-0.8％最佳。
“总量”是指被吸附到悬浮的微粒剂上的阳离子沉积聚合物加上游离的阳离子沉积聚合物(如果存在的话)。
“游离阳离子沉积聚合物”是指在洗涤组合物中没有吸附到颗粒剂上的阳离子沉积聚合物。
在本发明洗涤组合物中，按组合物中存在的阳离子聚合物的总重量计，吸附到悬浮的微粒剂上的阳离子聚合物的比例必须为至少5％，该比例优选至少30％，更优选至少40％，至少50％最佳。
(IV)
含水载体
本发明洗涤组合物含有含水载体。本发明组合物的载体主要是水，但为了促进不能充分溶于水的组分溶解，也可使用非水溶剂。适合的非水溶剂包括低级醇，例如乙醇和丙醇；多元醇例如甘油；二醇或二醇醚，例如2-丁氧基乙醇、乙二醇、乙二醇一乙醚、丙二醇、和二甘醇一乙醚或二甘醇一甲醚及其混合物。
按组合物总重量计，最终所得洗涤组合物中水的含量一般为20％-99％，优选40％-90％，更优选60％-90％，最理想的是70％-90％。
(V)
视需要加入的组分
根据所用组合物的类型，可向本发明组合物中加入一种或多种个人养护制剂中常用的附加组分。这样的附加组分包括不透明剂，例如聚乙二醇二硬脂酸酯和乙二醇硬脂酸酯，聚合物胶乳，附加杀微生物剂，例如ZnPTO和羟甲辛吡酮，泡沫促进剂，香料，着色剂，防腐剂，粘度调节剂，蛋白质，聚合物，缓冲剂或pH调节剂，润湿剂，香草或其他的植物提取物以及其它天然成分。
每一种这些成分都以能有效实现其目标的量存在。这些任选组分通常各自以占组合物总重量最高至约5％的含量包含在本发明组合物中。
优选用于处理头发的本发明组合物还含有适于头发养护的辅助剂。这些辅助剂一般以占组合物总重量最高2％、优选最高1％的含量包含在本发明组合物中。
合适的头发养护辅助剂有：
(i)天然发根营养素，例如氨基酸和糖。适合的氨基酸的实例包括精氨酸、半胱氨酸、谷氨酰胺、谷氨酸、异亮氨酸、亮氨酸、甲硫氨酸、丝氨酸和缬氨酸和/或其前体和衍生物。氨基酸可以单个加入，混合加入，或以肽形式，如二肽和三肽形式加入。氨基酸还可以以蛋白质水解产物的形式，如角蛋白或胶原水解产物形式加入。合适的糖有葡萄糖、右旋糖和果糖。这些糖可以单独加入或以例如水果提取物的形式加入。特别优选包含在本发明组合物中的天然发根营养素的组合是异亮氨酸与葡萄糖。特别优选的氨基酸营养素是精氨酸。
(ii)头发纤维养护剂，其实例有：
用于湿润纤维和保养表皮完整的神经酰胺。神经酰胺可从天然原料中提取获得，也可作为合成神经酰胺和伪神酰胺而获得。优选的神经酰胺是神经酰胺II，购自Quest。神经酰胺混合物也是合适的，例如神经酰胺LS，购自Laboratoires Serobiologiques。
用于表皮修复和预防损害的脂肪酸。其实例是支链脂肪酸，如18-甲基花生酸以及此系列其它同系物，直链脂肪酸，如硬脂酸、肉豆蔻酸和棕榈酸，和不饱和脂肪酸，例如油酸、亚油酸、亚麻酸和花生四烯酸。优选的脂肪酸是油酸。这些脂肪酸可以单独加入，混合加入，或者以得自提取物的混合物，如羊毛脂的形式加入。
也可以使用上述活性组分的混合物。
(VI)
本发明洗涤组合物的应用
本发明洗涤组合物可以呈对其所包含和要沉积的吸附颗粒剂来说相宜的任何适当形式。通过适当地选择必需和非必需组分及其相对量，本发明洗涤组合物可以例如呈洗发香波和调理剂以及其它洗去型头发处理组合物、沐浴香波、淋浴凝胶、洗面组合物、和泡沫浴液等形式。
如果需要的话，沐浴或洗发香波形式的优选组合物可涂在皮肤或头发上，并让其产生泡沫。可让泡沫在涂敷部位保留短时间例如一或几分钟后再清洗，或者也可以直接清洗。如果需要的话可重复该过程。
让泡沫保留在涂敷部位和重复涂敷可有助于进一步提高悬浮的微粒剂在皮肤或头发表面上的沉积量或速度，和/或将其递送到头发滤泡上。
通过下述非限制性实施例进一步举例说明本发明。
实施例
制备具有如下表所示组分的香波组合物：
| 组分 | 活性物量(wt％) | 商品名&供应商 |
| 月桂基醚硫酸钠 | 14 | Empicol ESB70(Albright和Wilson) |
| 椰油酰氨基丙基甜菜碱 | 2 | Tegobetaine CK(Goldschmidt) |
| 瓜尔胶羟丙基氯化三铵 | 0.03 | Jaguar C13S(Rhodia) |
| 聚二甲基硅氧烷醇微乳液 | 0.8 | DC2-1391(Dow Corning) |
| 氯化钠 | 0.5 | |
| 水 | 至100 |
制备该香波的方法如下：若配制100g香波，将0.018g瓜尔胶羟丙基氯化三铵溶于该制剂用的游离水中，并将pH调节至9。加入聚二甲基硅氧烷醇微乳液，并充分搅拌20分钟。将该混合物的pH调节至6，然后将其与该制剂的其它组分，以及其余的瓜尔胶羟丙基氯化三铵合并。
Claims (3)
1.一种头发或身体洗涤组合物的制备方法，所述方法包括以下步骤：
(i)配制阳离子沉积聚合物的水溶液，所述阳离子沉积聚合物选自阳离子纤维素和阳离子瓜尔胶衍生物；
(ii)向所得溶液中加入悬浮的微粒剂；
(iii)调节溶液的pH值，使之达到阳离子沉积聚合物等电点的1.5个pH单位之内并混合；
(iv)再调节混合物的pH值以此给阳离子沉积聚合物再充电；以及
(v)将如此获得的混合物与一种基质头发或身体香波组合物混合，所述洗涤组合物含有至少一种选自阴离子表面活性剂、加以改变而带有负电荷的两性表面活性剂和它们的混合物的去污表面活性剂。
2.权利要求1的方法，其中所述悬浮的微粒剂是乳化的硅氧烷或聚异丁烯。
3.权利要求1或2的方法，其中所述去污表面活性剂选自烷基硫酸盐、烷基醚硫酸盐和它们的混合物。
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Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2811884B1 (fr) * | 2000-07-21 | 2003-01-31 | Oreal | Utilisation en cosmetique de betainates d'amidon et composition les comprenant associes a au moins un agent benefique pour les matieres keratiniques |
| DE10111288A1 (de) * | 2001-03-09 | 2002-09-12 | Wella Ag | Antischuppenmittel |
| WO2003005986A1 (en) * | 2001-07-11 | 2003-01-23 | Unilever Plc | Hair treatment compositions |
| JP4101766B2 (ja) * | 2002-02-20 | 2008-06-18 | ザ プロクター アンド ギャンブル カンパニー | パーソナルクレンジング組成物 |
| GB0209136D0 (en) * | 2002-04-22 | 2002-05-29 | Procter & Gamble | Durable hair treatment composition |
| DE10224026A1 (de) * | 2002-05-31 | 2003-12-11 | Beiersdorf Ag | Konditionierendes Haarshampoo |
| EP1384470B2 (en) * | 2002-07-22 | 2014-09-24 | Kao Corporation | Skin cleansing composition |
| JP2004107319A (ja) * | 2002-07-22 | 2004-04-08 | Kao Corp | 皮膚洗浄剤組成物 |
| US6780826B2 (en) * | 2002-09-11 | 2004-08-24 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Oil-containing personal wash compositions or emulsions comprising particles of high refractive index and defined thickness, geometry and size |
| CN100464731C (zh) * | 2003-05-23 | 2009-03-04 | 宝洁公司 | 包含阳离子调理聚合物和阴离子表面活性剂体系的澄清的个人护理组合物 |
| WO2004105711A2 (en) * | 2003-05-23 | 2004-12-09 | The Procter & Gamble Company | Clear personal care compositions containing a cationic conditioning polymer and an anionic surfactant system |
| WO2005072687A1 (en) * | 2004-01-16 | 2005-08-11 | The Procter & Gamble Company | Conditioning shampoo compositions |
| US6906015B1 (en) | 2004-03-31 | 2005-06-14 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Ordered liquid crystalline cleansing composition with particulate optical modifiers |
| CA2561501C (en) * | 2004-03-31 | 2013-05-28 | Unilever Plc | Liquid cleansing composition with particulate optical modifiers |
| US7202199B2 (en) * | 2004-03-31 | 2007-04-10 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Isotropic cleansing composition with particulate optical modifiers |
| US20080029119A1 (en) * | 2004-07-01 | 2008-02-07 | Barbara Jean Fealy | Novel Cleansing Composition |
| MX2007008451A (es) * | 2005-01-12 | 2008-03-13 | Amcol International Corp | Composiciones detergentes que contienen agentes de beneficio hidrofobico, pre-emulsificados usando particulas cationicas coloidales. |
| GB0518059D0 (en) * | 2005-09-06 | 2005-10-12 | Dow Corning | Delivery system for releasing active ingredients |
| US7723453B2 (en) * | 2006-05-04 | 2010-05-25 | Conopco, Inc. | Hydrophobically modified cationic polymers |
| FR2906714A1 (fr) * | 2006-10-04 | 2008-04-11 | Oreal | Composition de nettoyage contenant des particules hemispheriques creuses |
| DE102007017307A1 (de) | 2007-04-11 | 2008-10-16 | Beiersdorf Ag | Zubereitung zur Pflege des Haares, enthaltend ein ampholytisches Copolymer |
| EP2200443B2 (en) | 2007-09-17 | 2021-06-30 | Cornell University | Branched chain fatty acids for prevention or treatment of gastrointestinal disorders |
| WO2010014614A2 (en) * | 2008-07-28 | 2010-02-04 | The Procter & Gamble Company | Multiphase personal care composition with enhanced deposition |
| US8124064B2 (en) * | 2008-07-28 | 2012-02-28 | The Procter & Gamble Company | In-vitro deposition evaluation method for identifying personal care compositions which provide improved deposition of benefit agents |
| ES2517923T3 (es) | 2009-03-05 | 2014-11-04 | Basf Se | Terpolímeros anfolíticos para su uso en composiciones para el cuidado personal |
| KR102225683B1 (ko) * | 2014-10-30 | 2021-03-10 | (주)아모레퍼시픽 | 세정제 조성물 |
| US11969490B2 (en) | 2020-06-29 | 2024-04-30 | The Procter & Gamble Company | Hair conditioning composition with antimicrobial system |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA810625A (en) * | 1965-07-30 | 1969-04-15 | The Procter & Gamble Company | Antimicrobial detergent compositions |
| US3489686A (en) * | 1965-07-30 | 1970-01-13 | Procter & Gamble | Detergent compositions containing particle deposition enhancing agents |
| US3580853A (en) | 1967-09-27 | 1971-05-25 | Procter & Gamble | Detergent compositions containing particle deposition enhancing agents |
| DK132838A (zh) * | 1967-12-11 | |||
| GB8903777D0 (en) | 1989-02-20 | 1989-04-05 | Unilever Plc | Shampoo composition |
| EP0432951B2 (en) * | 1989-12-04 | 2004-06-30 | Unilever Plc | Hair treatment composition |
| GB9016100D0 (en) * | 1990-07-23 | 1990-09-05 | Unilever Plc | Shampoo composition |
| AU647849B2 (en) * | 1990-12-13 | 1994-03-31 | Unilever Plc | Hair styling composition |
| BR9206689A (pt) * | 1991-10-29 | 1995-05-02 | Procter & Gamble | Composições de xampu com silicone; polímero catiônico e agentes de condicionamento líquidos oleosos |
| WO1995022311A1 (en) * | 1994-02-18 | 1995-08-24 | Unilever Plc | Personal washing compositions |
| EP0796084B1 (en) * | 1994-12-06 | 1999-05-06 | The Procter & Gamble Company | Shelf stable skin cleansing liquid with gel forming polymer, lipid and crystalline ethylene glycol fatty acid ester |
| CN1185733A (zh) * | 1995-03-29 | 1998-06-24 | 尤尼利弗公司 | 液体清洗剂组合物 |
| US5891833A (en) * | 1996-06-20 | 1999-04-06 | The Procter & Gamble Company | Process for preparing liquid personal cleansing compositions which provide enhanced perfume deposition |
| US5843875A (en) * | 1996-06-20 | 1998-12-01 | The Procter & Gamble Company | Perfume delivery systems in liquid personal cleansing |
| GB9622659D0 (en) * | 1996-10-31 | 1997-01-08 | Unilever Plc | Hair treatment composition |
-
1998
- 1998-12-10 GB GBGB9827224.8A patent/GB9827224D0/en not_active Ceased
-
1999
- 1999-11-29 AU AU15581/00A patent/AU761268B2/en not_active Ceased
- 1999-11-29 BR BRPI9916045-5A patent/BR9916045B1/pt not_active IP Right Cessation
- 1999-11-29 PL PL348886A patent/PL199173B1/pl not_active IP Right Cessation
- 1999-11-29 AT AT99958146T patent/ATE258785T1/de not_active IP Right Cessation
- 1999-11-29 CN CNB998160431A patent/CN1165288C/zh not_active Expired - Fee Related
- 1999-11-29 EP EP99958146A patent/EP1137397B1/en not_active Expired - Lifetime
- 1999-11-29 CA CA002354048A patent/CA2354048A1/en not_active Abandoned
- 1999-11-29 ES ES99958146T patent/ES2214903T3/es not_active Expired - Lifetime
- 1999-11-29 DE DE69914629T patent/DE69914629T2/de not_active Expired - Lifetime
- 1999-11-29 JP JP2000586301A patent/JP4502512B2/ja not_active Expired - Fee Related
- 1999-11-29 WO PCT/EP1999/009328 patent/WO2000033807A1/en active IP Right Grant
- 1999-12-07 US US09/456,003 patent/US6348188B1/en not_active Expired - Fee Related
- 1999-12-13 AR ARP990106308A patent/AR021624A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69914629D1 (de) | 2004-03-11 |
| AU761268B2 (en) | 2003-05-29 |
| CA2354048A1 (en) | 2000-06-15 |
| ES2214903T3 (es) | 2004-09-16 |
| AU1558100A (en) | 2000-06-26 |
| WO2000033807A1 (en) | 2000-06-15 |
| BR9916045B1 (pt) | 2010-10-05 |
| BR9916045A (pt) | 2001-10-02 |
| ATE258785T1 (de) | 2004-02-15 |
| PL348886A1 (en) | 2002-06-17 |
| EP1137397B1 (en) | 2004-02-04 |
| PL199173B1 (pl) | 2008-08-29 |
| US6348188B1 (en) | 2002-02-19 |
| JP4502512B2 (ja) | 2010-07-14 |
| JP2002531638A (ja) | 2002-09-24 |
| DE69914629T2 (de) | 2004-12-09 |
| CN1334721A (zh) | 2002-02-06 |
| GB9827224D0 (en) | 1999-02-03 |
| AR021624A1 (es) | 2002-07-31 |
| EP1137397A1 (en) | 2001-10-04 |
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
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Granted publication date: 20040908 Termination date: 20101129 |