CN116492267B

CN116492267B - Plant anti-dandruff shampoo and preparation method thereof

Info

Publication number: CN116492267B
Application number: CN202310736699.7A
Authority: CN
Inventors: 李湘佩
Original assignee: Guangzhou Zanyu Cosmetics Co ltd
Current assignee: Guangzhou Zanyu Cosmetics Co ltd
Priority date: 2023-06-21
Filing date: 2023-06-21
Publication date: 2023-12-22
Anticipated expiration: 2043-06-21
Also published as: CN116492267A

Abstract

The plant anti-dandruff shampoo comprises a traditional Chinese medicine composition extract, has the effects of inhibiting and killing bacteria, and can inhibit and relieve dandruff. The traditional Chinese medicine composition extracting solution comprises the following components in parts by weight: 20-30 parts of a dog tail grass ear, 10-20 parts of mugwort leaf, 10-15 parts of dandelion, 10-15 parts of phellodendron, 10-15 parts of Chinese honeylocust, 5-8 parts of liquorice and 3-8 parts of mint. The method adopts pure natural traditional Chinese medicinal materials, and utilizes the characteristics of traditional Chinese medicinal components to extract the active ingredients of the traditional Chinese medicinal materials through the steps of crushing, steaming, fermenting, steaming, juicing, distilling, standing, filtering and the like. In addition, the ethanol produced in the fermentation process is used as an extraction solvent of other traditional Chinese medicinal material active ingredients, so that the production cost can be reduced, and the separation difficulty of the ethanol in the later stage can be reduced.

Description

Plant anti-dandruff shampoo and preparation method thereof

Technical Field

The application belongs to the field of daily cosmetics, and in particular relates to plant anti-dandruff shampoo and a preparation method thereof.

Background

Healthy scalp ecology is maintained by three major balances: grease, flora and metabolism balance. When scalp is oiled, harmful fungi like malassezia and the like, which are fond of fat, are propagated in a great amount in pores, so that the environment of scalp flora is unbalanced, and the scalp is itchy. Moreover, the excretions of these harmful bacteria can also irritate scalp cells, leading to dermatitis, accelerating the shedding of scalp cells and generating dandruff.

The anti-dandruff agents used earlier include sulfur, salicylic acid and the like, and the anti-dandruff agents have the effect of removing damaged epidermal cells in the stratum corneum by means of desquamation or reducing the replacement speed of the epidermal cells, but have high irritation and are easy to damage the scalp and hair follicles.

The existing anti-dandruff agents used in current use are Zinc Pyrithione (ZPT), ganbazole, pyridone ethanolamine salt (OCT) and the like, the aim of radically treating dandruff is achieved by inhibiting or destroying harmful bacteria, but the ZPT has certain toxicity and irritation, is insoluble in water and is easy to delaminate; OCT has good solubility, but color, and high price; the solubility and stability of the gamboge are good, but the sterilization effect is poorer than that of ZPT and OCT.

In order to solve the above problems, a number of Chinese medicinal preparations with antibacterial and bactericidal effects have been developed, for example, chinese patent application publication No. CN101569600a discloses an antibacterial Chinese medicinal additive for bath emulsion, ethanol is used as solvent to extract the active ingredients of the Chinese medicinal materials, and finally the ethanol is separated. The method for extracting the active ingredients of the traditional Chinese medicine has the advantages of large ethanol consumption, difficult separation and poor extraction effect.

Disclosure of Invention

In order to solve the problems of large ethanol consumption, difficult separation and poor extraction effect when the active ingredients of the traditional Chinese medicine are extracted by adopting an ethanol extraction method, the application provides a plant anti-dandruff shampoo and a preparation method thereof.

In a first aspect, the present application provides a plant anti-dandruff shampoo comprising the following components in weight percent: 14.25-15.75% of AES/70, 2.85-3.15% of LSA/70, 2.38-2.63% of 6501, 0.19-0.21% of cationic guar gum, 0.76-0.84% of polyquaternium, 0.5-2.0% of traditional Chinese medicine composition extract, 2.85-3.15% of emulsified silicone oil, 0.19-0.21% of sodium benzoate, 0.11-0.13% of citric acid, 0.48-0.53% of sodium chloride, 0.38-0.42% of essence and the balance of deionized water;

the extraction method of the traditional Chinese medicine composition extract comprises the following steps:

s1: respectively weighing 20-30 parts of a dog tail grass ear, 15-20 parts of mugwort leaf, 10-15 parts of dandelion, 10-15 parts of phellodendron, 10-15 parts of Chinese honeylocust, 5-8 parts of liquorice and 3-8 parts of mint, and performing air drying and crushing to obtain crushed powder for later use;

s2: uniformly mixing the crushed dog tail grass ears with water, and steaming to obtain a steamed material;

s3: cooling the cooking material, adding distiller's yeast, stirring uniformly, and fermenting to obtain a fermentation material;

s4: mixing the crushed folium artemisiae argyi, dandelion, phellodendron, chinese honeylocust fruit, liquorice and mint with the fermented material, adding water, uniformly stirring, steaming, and juicing to obtain juice;

s5: distilling the material juice, standing, and filtering to obtain the Chinese medicinal composition extractive solution.

By adopting the technical scheme, the traditional Chinese medicine composition extract added into the plant anti-dandruff shampoo takes pure natural traditional Chinese medicinal materials as raw materials, and contains various active ingredients with antibacterial and bactericidal effects. For example, the dog tail grass ear contains furfural substances which can act on the hydrophobic groups, hydroxyl groups, carboxyl groups and amino groups of bacteria or fungi body proteins to alkylate the bacteria or fungi body proteins, so that the bacteria or fungi death is caused by the solidification of the proteins.

In addition, the polyquaternary ammonium salt cationic surfactant can improve the physical permeability of aldehyde groups in furfural substances, so that the polyquaternary ammonium salt cationic surfactant can penetrate cell walls and cell membranes of bacteria or fungi more easily. And when in use, the surface activity of the polyquaternium can also effectively inhibit the polymerization between furfural molecules, thereby improving the sterilization effect of furfural substances.

In addition, polyphenol and volatile oil components in the herba et Gemma Agrimoniae, the folium artemisiae argyi and the fructus gleditsiae can interact with cell membranes of bacteria or fungi to change the permeability of the cell membranes, so that the contents of the bacteria or fungi flow out, and the effects of diminishing inflammation and sterilizing are achieved.

In view of this, in order to increase the content of active ingredients in the extract of the traditional Chinese medicine composition, the existing process generally adopts ethanol as an extractant for deep extraction, but excessive ethanol is added in the process, so that the later separation is difficult.

In this regard, the application first air-dries and pulverizes the dog tail spica, the mugwort leaf, the dandelion, the phellodendron, the gleditsia sinensis lam, the liquorice and the mint. Then, the chopped herba Setariae viridis is steamed to destroy the plant cell wall structure, promote the degradation of starch substances in plants and the exudation of internal active ingredients. And adding distiller's yeast for fermentation, wherein the microorganisms can produce various enzyme substances in the fermentation process, the produced cellulase and amylase can convert cellulose substances and starch into glucose, and the produced alcoholizing enzyme can convert the glucose into ethanol. Meanwhile, in the fermentation process, the extraction effect of ethanol and the degradation effect of microorganisms are beneficial to the dissolution of more active ingredients in the dog tail grass ears.

Then, the traditional Chinese medicines such as the mugwort leaf and the dandelion are mixed with the fermented materials and then are steamed, ethanol generated in the fermentation process can be used as an extraction solvent, active ingredients in the traditional Chinese medicines such as the mugwort leaf and the dandelion are extracted in the steaming process, finally, the ethanol is distilled out, and the mixture is stood and filtered to obtain the traditional Chinese medicine composition extract with higher content of active ingredients. Moreover, the traditional Chinese medicine active ingredients are extracted by adopting the steaming-fermenting-steaming extraction composite process, and ethanol is not required to be additionally added for extraction, so that the distillation and separation are easy.

Preferably, in the above extraction step S2, the Lewis acid catalyst is added while the fine powder of the Tinospora cordifolia is mixed with water.

In the scheme, the cellulose structure of the dog tail grass ear is divided into a crystallization area and a non-crystallization area, fiber molecules are connected through regular hydrogen bond arrangement in the crystallization area, and the non-crystallization area is also provided with hydrogen bonds among the fiber molecules, but the arrangement is irregular, the density is smaller than that of the crystallization area, and small molecular substances are easy to enter. In the cooking process, the Lewis acid catalyst easily permeates into the non-crystallization area of the dog tail spica cellulose and preferentially reacts with the non-crystallization area, so that the average polymerization degree of the cellulose is reduced. The partial degradation of cellulose is beneficial to the decomposition of starch substances in the dog tail grass ears and the exudation of bactericidal active ingredients.

On the other hand, in the fermentation process of the dog tail grass ears, enzymes produced by microorganisms catalyze cellulose and starch to convert into glucose, the glucose can be dehydrated and isomerized into fructose under the action of a Lewis acid catalyst, and then the fructose is combined with water to produce furfural substances, so that more glucose is promoted to be converted into furfural substances, the content of the furfural substances is improved, and the sterilization effect can be enhanced when the dog tail grass ears are used. At this time, part of glucose is converted into furfural substances, so that the amount of glucose used for conversion into ethanol is reduced, the content of ethanol in the fermentation broth can be controlled within a proper range while the extraction effect is ensured, and the subsequent distillation separation of ethanol is facilitated.

Preferably, the weight ratio of dog tail fines to Lewis acid catalyst is (34-75): 1.

In the technical scheme, the applicant finds that when the addition amount of the Lewis acid catalyst is too small, the cellulose degradation of the dog tail grass ears in the cooking process is slow, the exudation of the sterilization active ingredients is not facilitated, and the sterilization effect is reduced. Meanwhile, in the fermentation process, furfural substances converted by glucose are reduced, the amount of converted ethanol is increased, and the separation of final ethanol is not facilitated.

Conversely, when the addition amount of the Lewis acid catalyst is excessive, the degradation rate of cellulose of the dog tail grass ears in the cooking process is high, and the degradation of starch substances is promoted. When fermenting, under the action of microorganism, small molecule cellulose and starch are quickly converted into glucose, and most of glucose is quickly converted into ethanol when being not converted into furfural substances, so that the produced ethanol is excessive, and the separation is difficult. In addition, too much catalyst is added, too much exogenous substances are introduced, the quality of the shampoo is affected, and the cost is increased.

Preferably, the lewis acid catalyst is one or more of aluminum chloride, ferric chloride and zinc chloride.

The three Lewis acid catalysts in the technical scheme have high catalytic activity, are all easy to dissolve in water and ethanol, and are easy to uniformly disperse in a steaming and boiling and fermentation system, and the catalytic effect is better.

In addition, aluminum chloride and ferric chloride can adapt to various reaction conditions, have low requirements on conditions such as temperature, pressure, reactant concentration and the like, and can exert excellent catalytic effects in different industrial production environments. In addition, in the cooking and fermentation processes, part of aluminum chloride and ferric chloride can be subjected to hydrolysis reaction with water to generate proper amount of aluminum hydroxide and ferric hydroxide, so that a certain flocculation effect is achieved, and some impurities and heavy metal ions can be settled.

In addition, aluminum chloride, ferric chloride and zinc chloride can be used for swelling and peptizing cellulose of traditional Chinese medicine plants so as to dissolve cellulose, so that a plurality of migration and exudation channels are formed in plant cellulose tissues, and the precipitation of bactericidal active ingredients is facilitated.

Preferably, the modification method of the Lewis acid catalyst comprises the following steps:

1) Respectively weighing 0.5-0.8 part of high molecular hydrogel and 0.05-0.08 part of Lewis acid catalyst, dissolving in water, drying and grinding to obtain powder;

2) Spraying hydrophobic liquid while stirring powder to obtain intermediate material;

3) Respectively weighing 1.7-2.6 parts of polymer hydrogel and 0.34-0.51 part of Lewis acid, dissolving in water, adding intermediate materials, rapidly stirring uniformly, drying and grinding.

By adopting the technical scheme, firstly, a large amount of high molecular hydrogel and a small amount of Lewis acid catalyst are mixed and dissolved in water, and at the moment, the Lewis acid catalyst is uniformly distributed in the mixture and is in a wrapped state. And then drying and grinding the mixture to obtain powder particles.

And then weighing less polymer hydrogel, more Lewis acid catalyst and water, mixing uniformly to obtain gel mixed solution, adding the powder particles prepared in the step 1) into the gel mixed solution as an inner core, and stirring uniformly to ensure that the powder particles are uniformly distributed in the gel mixed solution.

In the stirring process, as the moisture in the gel mixed solution can permeate the powder particles to cause swelling and disintegration of the powder particles, in the step 2), the hydrophobic liquid is sprayed on the surfaces of the powder particles to prevent and inhibit the permeation of the moisture to the powder particles, so that the integrity and the drying state of the powder particles are maintained, and the exchange and doping between the gel mixed solution and the powder particles are reduced.

And finally, drying and grinding the gel mixed solution containing the powder particles.

The product produced by the above steps is a composite particulate having a coating and a plurality of powder particles distributed within the coating. By utilizing the structural characteristic, when the dog tail grass ears are steamed, the coating body firstly absorbs water and swells, and the Lewis acid catalyst in the coating body is slowly released into the steamed material to catalyze the degradation of plant cellulose of the traditional Chinese medicine. Along with the extension of the cooking time, the powder particles are gradually swelled, and when the dog tail grass ears are fermented, the Lewis acid catalyst in the powder particles is slowly released into the fermentation material to catalyze the glucose to be dehydrated and converted into furfural substances.

The catalyst is in a composite particle structure because the consumption of the Lewis acid catalyst is different in the cooking and fermentation processes of the dog tail grass ears, so that the problems that the degradation rate of the traditional Chinese medicine plant cellulose is too high due to excessive catalyst in the cooking process and the catalyst is too low in the fermentation process, so that glucose is not easy to dehydrate and convert into furfural substances, excessive ethanol is generated, and the distillation and separation are unfavorable are effectively avoided.

Preferably, the high molecular hydrogel is one or more of agarose, guar gum and carrageenan.

Agarose, guar gum and carrageenan used in the technical scheme have excellent water absorption and water retention, can be swelled and dissolved in hot water, have increased solubility in slightly acidic solution, and are in a stable gel state in warm water or cold water.

In the scheme, the guar gum has good stability and can stably play a role in a reaction system of the application; the carrageenan can have synergistic effect with other hydrogels, and can improve the elasticity and water retention of the gel; agarose has no charged group, and can not cause denaturation and adsorption to sensitive biomacromolecules, thus being an ideal inert carrier. The three kinds of high molecular hydrogels are most suitable for modifying Lewis acid catalysts, preferably guar gum, and can better regulate the release speed of the catalysts so as to generate proper amount of ethanol, so that the distillation separation is easy to be carried out in the later stage, and the effective extraction of active ingredients of traditional Chinese medicines such as the dog tail grass ears, the mugwort leaves, the dandelion and the like can be ensured.

The polymer hydrogel adopting the scheme can be quickly swelled and dissolved to release the Lewis acid catalyst when the temperature is higher in the cooking process; and when the temperature is lower in the fermentation process, the catalyst is in a stable gel state, the Lewis acid catalyst is difficult to release, and when the catalyst is heated to 90-100 ℃, the catalyst is slowly dissolved again to release the catalyst, so that the glucose is catalyzed to be dehydrated and converted into furfural substances.

Preferably, the fermentation process of step S3 and the digestion process of step S4 further comprise a condensation reflux operation.

By adopting the technical scheme, in the fermentation process, ethanol generated by glucose under the action of microorganisms can be used as an extraction solvent of active ingredients in the dog tail grass ears; on the other hand, the fermented material containing ethanol is also mixed with traditional Chinese medicines such as mugwort leaf and dandelion for cooking in the step S4, so that in the fermentation process of the step S3, if condensation reflux is not carried out, part of ethanol can volatilize, thereby affecting the extraction of active ingredients of the traditional Chinese medicines such as the dog tail grass spike, mugwort leaf and dandelion.

Similarly, in the cooking process of step S4, because the added fermented material contains ethanol, the fermented material can be used as an extraction solvent for active ingredients of traditional Chinese medicines such as mugwort leaf and dandelion, if no condensation reflux is performed, part of ethanol can volatilize, the ethanol content in the system is reduced, and the extraction effect is poor.

In a second aspect, the application provides a preparation method of plant anti-dandruff shampoo, which comprises the steps of firstly weighing AES/70, LSA/70, 6501, cationic guar gum, polyquaternium-10, traditional Chinese medicine composition extract, emulsified silicone oil, sodium benzoate, citric acid, sodium chloride, essence and deionized water according to a formula, and then mixing and stirring uniformly.

According to the technical scheme, the traditional Chinese medicine composition extract is uniformly dispersed in the shampoo, so that the antibacterial and bactericidal effects of the traditional Chinese medicine composition extract are achieved, and the dandruff is inhibited or relieved.

In summary, the present application has the following beneficial effects:

1. the application takes pure natural Chinese herbal medicines as raw materials, the Chinese herbal medicines contain active ingredients such as furfural, polyphenol, volatile oil and the like, the ingredients have good antibacterial and sterilizing effects, and the ingredients can cooperate with surfactants in shampoo to enhance the sterilizing effects, so that the effects of inhibiting and relieving dandruff are achieved.

2. According to the method, an extraction method is selected according to the characteristics of Chinese herbal medicine raw materials, and the tendril grass ears with rich starch content are extracted by adopting a microbial fermentation method, so that not only is active ingredients fully extracted, but also the molecular weight of the active ingredients can be reduced, the penetrability of the active ingredients to scalp is increased, and the antibacterial and bactericidal effects of the active ingredients are improved; the ethanol produced is used as an extraction solvent for the active ingredients of the traditional Chinese medicine, so that the ethanol production is controlled while the extraction of the active ingredients of the traditional Chinese medicine is ensured, the separation difficulty is reduced, and the cost is reduced.

3. The Lewis acid catalyst is added in the method, so that on one hand, the degradation of cellulose in the traditional Chinese medicine can be catalyzed, and the exudation of active ingredients in the traditional Chinese medicine is facilitated; on the other hand, the method can catalyze the conversion of glucose into furfural substances, control the generation of proper amount of ethanol, not only enhance the sterilization effect, but also avoid the generation of excessive ethanol to cause difficult separation.

4. In the application, because the application occasions and the application amount of the Lewis acid catalyst are different, the Lewis acid catalyst is modified to prepare composite particles, and the release speed of the Lewis acid catalyst in a catalytic system is controlled, so that the production amount of ethanol and furfural substances is controlled.

Drawings

Fig. 1: figures of the change trend of the average blank dandruff values and average dandruff values in examples 1 to 22 and comparative example 1 of the present application.

Fig. 2: trend graphs of 5-hydroxymethylfurfural content in examples 1 to 22 and comparative example 1 of the present application.

Fig. 3: trend graphs of ethanol content in examples 1-22 of the present application.

Detailed Description

The present application is described in further detail below with reference to examples.

The raw materials of the examples and comparative examples herein are commercially available in general unless otherwise specified.

The AES/70, LSA/70 and 6501 feedstock information in this example and comparative example are shown in Table 1.

TABLE 1 AES/70, LSA/70 and 6501 raw material information tables in the examples and comparative examples

Examples

Example 1

The plant anti-dandruff shampoo of the embodiment comprises the following components in percentage by weight: 14.25% of AES/70, 2.85% of LSA/70, 2.38% of 6501, 0.19% of cationic guar gum, 0.76% of polyquaternium-10, 0.5% of traditional Chinese medicine composition extract, 2.85% of emulsified silicone oil, 0.19% of sodium benzoate, 0.11% of citric acid, 0.48% of sodium chloride, 0.38% of essence and the balance of deionized water;

the extraction method of the traditional Chinese medicine composition extracting solution comprises the following steps:

s1: respectively weighing 20kg of dog tail grass ears, 15kg of mugwort leaves, 10kg of dandelion, 10kg of amur corktree bark, 10kg of Chinese honeylocust fruits, 5kg of liquorice and 3kg of peppermint, respectively placing into a 50 ℃ oven for hot air drying, and then respectively placing into a traditional Chinese medicine pulverizer for pulverizing, wherein the fineness is 60 meshes;

s2: putting the crushed dog tail grass ears into a cooking pot, adding equal amount of deionized water, uniformly stirring, heating to 90 ℃, preserving heat for 3 hours, and taking out of the pot to obtain a cooking material;

s3: scattering and cooling the steamed material to 26 ℃, adding a proper amount of sweet wine distiller's yeast, uniformly stirring, immediately placing the steamed material into a jar, sealing and fermenting at a maintained temperature for 5 days to obtain a fermented material;

s4: adding the fermented material, the artemisia argyi, dandelion, phellodendron bark, chinese honeylocust fruit, liquorice and mint powder into a cooking pot, adding equal amount of deionized water, uniformly mixing, heating to 70 ℃ for cooking, preserving heat for 24 hours, taking out of the pot, and putting into an oil press after taking out of the pot to obtain juice;

s5: and (3) placing the material juice into a vacuum distillation kettle, distilling out ethanol in the material juice at the temperature below 70 ℃, standing the distilled material juice, and filtering to obtain transparent liquid, namely the traditional Chinese medicine composition extract.

The preparation method of the plant anti-dandruff shampoo comprises the following steps:

142.5g of AES/70, 28.5g of LSA/70, 6501.8 g of cationic guar gum 1.9g, 7.6g of polyquaternium-10.0 g of traditional Chinese medicine composition extract, 28.5g of emulsified silicone oil, 1.9g of sodium benzoate, 1.1g of citric acid, 4.8g of sodium chloride, 3.8g of essence and 750.6g of deionized water are respectively weighed, mixed and stirred uniformly.

Example 2

The plant anti-dandruff shampoo of the embodiment comprises the following components in percentage by weight: 15.75% of AES/70, 3.15% of LSA/70, 6501.63% of cationic guar gum 0.21%, 0.84% of polyquaternium-10.5% of traditional Chinese medicine composition extract, 3.15% of emulsified silicone oil, 0.21% of sodium benzoate, 0.13% of citric acid, 0.53% of sodium chloride, 0.42% of essence and the balance of deionized water;

the extraction method of the extract of the Chinese medicinal composition of this example is the same as that of example 1.

respectively weighing 157.5g of AES/70, 31.5g of LSA/70, 6501.3 g of cationic guar gum, 2.1g of polyquaternium-10.4 g of traditional Chinese medicine composition extract, 5.0g of emulsified silicone oil, 31.5g of sodium benzoate, 2.1g of citric acid, 5.3g of sodium chloride, 4.2g of essence and 724.8g of deionized water, mixing and stirring uniformly.

Example 3

The plant anti-dandruff shampoo of the embodiment comprises the following components in percentage by weight: 15% of AES/70%, 3% of LSA/70%, 6501.5% of cationic guar gum 0.2%, 0.8% of polyquaternium-10.8%, 0.5% of traditional Chinese medicine composition extract, 3% of emulsified silicone oil, 0.2% of sodium benzoate, 0.12% of citric acid, 0.5% of sodium chloride, 0.4% of essence and the balance of deionized water;

respectively weighing 150.0g of AES/70, 30.0g of LSA/70, 6501.0 g of cationic guar gum, 2.0g of polyquaternium-10.0 g of traditional Chinese medicine composition extract, 5.0g of emulsified silicone oil, 30.0g of sodium benzoate, 1.2g of citric acid, 5.0g of sodium chloride, 4.0g of essence and 737.8g of deionized water, mixing and stirring uniformly.

Example 4

The plant anti-dandruff shampoo of the embodiment comprises 1.5 weight percent of the traditional Chinese medicine composition extract, and the weight percent of the rest components is the same as that of the embodiment 3;

the extraction method of the extract of the Chinese medicinal composition of this example is the same as that of example 3.

respectively weighing 150.0g of AES/70, 30.0g of LSA/70, 6501.0 g of cationic guar gum, 2.0g of polyquaternium-10.0 g of traditional Chinese medicine composition extract, 15.0g of emulsified silicone oil, 30.0g of sodium benzoate, 2.0g of citric acid, 5.0g of sodium chloride, 4.0g of essence and 727.8g of deionized water, mixing and stirring uniformly.

Example 5

The plant anti-dandruff shampoo of the embodiment comprises 2.0 weight percent of the traditional Chinese medicine composition extract, and the weight percent of the rest components is the same as that of the embodiment 3;

respectively weighing 150.0g of AES/70, 30.0g of LSA/70, 6501.0 g of cationic guar gum, 2.0g of polyquaternium-10.0 g of traditional Chinese medicine composition extract, 20.0g of emulsified silicone oil, 30.0g of sodium benzoate, 1.2g of citric acid, 5.0g of sodium chloride, 4.0g of essence and 722.8g of deionized water, mixing and stirring uniformly.

Example 6

The component content of the plant anti-dandruff shampoo of this example is the same as that of example 4;

s1: respectively weighing 25kg of dog tail grass ears, 18kg of mugwort leaves, 13kg of dandelion, 13kg of phellodendron bark, 13kg of Chinese honeylocust fruits, 7kg of liquorice and 5kg of peppermint, respectively placing into a 50 ℃ oven for hot air drying, and then respectively placing into a traditional Chinese medicine pulverizer for pulverizing, wherein the fineness is 70 meshes;

s3: scattering and cooling the steamed material to 28 ℃, adding a proper amount of sweet wine distiller's yeast, uniformly stirring, immediately placing the steamed material into a jar, sealing and fermenting at a maintained temperature for 5 days to obtain a fermented material;

The preparation method of the plant anti-dandruff shampoo of the present example is the same as that of example 4.

Example 7

s1: respectively weighing 30kg of dog tail grass ears, 20kg of mugwort leaves, 15kg of dandelion, 15kg of phellodendron bark, 15kg of Chinese honeylocust fruits, 8kg of liquorice and 8kg of peppermint, respectively placing into a 50 ℃ oven for hot air drying, and then respectively placing into a traditional Chinese medicine pulverizer for pulverizing, wherein the fineness is 80 meshes;

s3: scattering and cooling the steamed material to 30 ℃, adding a proper amount of sweet wine distiller's yeast, uniformly stirring, immediately placing the steamed material into a jar, sealing and fermenting at a maintained temperature for 5 days to obtain a fermented material;

Example 8

The component content of the plant anti-dandruff shampoo of this example is the same as that of example 6;

the extraction method of the extract of the traditional Chinese medicine composition in this embodiment is different from that in embodiment 6 in that:

in the step S2, adding 0.71kg of zinc chloride catalyst into a cooking pot, uniformly mixing with the crushed grass and ear of the dog tail, heating to 90 ℃, preserving heat for 3 hours, and taking out of the pot to obtain a cooking material;

the remaining steps were the same as in example 6.

The preparation method of the plant anti-dandruff shampoo of the present example is the same as that of example 6.

Example 9

in the step S2, adding 0.71kg of ferric chloride catalyst into the cooking pot, uniformly mixing with the crushed grass and ear of the dog tail, heating to 90 ℃, preserving heat for 3 hours, and taking out of the pot to obtain a cooking material;

the remaining steps were the same as in example 6.

Example 10

in the step S2, adding 0.71kg of aluminum chloride catalyst into the cooking pot, uniformly mixing with the crushed grass and ear of the dog tail, heating to 90 ℃, preserving heat for 3 hours, and taking out of the pot to obtain a cooking material;

the remaining steps were the same as in example 6.

Example 11

The component content of the plant anti-dandruff shampoo of this example is the same as that of example 10;

the extraction method of the extract of the traditional Chinese medicine composition in this embodiment is different from that in embodiment 10 in that:

in the step S2, adding 0.45kg of aluminum chloride catalyst into the cooking pot, uniformly mixing with the crushed grass and ear of the dog tail, heating to 90 ℃, preserving heat for 3 hours, and taking out of the pot to obtain a cooking material;

the remaining steps were the same as in example 10.

The preparation method of the plant anti-dandruff shampoo of the present example is the same as that of example 10.

Example 12

in the step S2, adding 0.33kg of aluminum chloride catalyst into the cooking pot, uniformly mixing with the crushed grass and ear of the dog tail, heating to 90 ℃, preserving heat for 3 hours, and taking out of the pot to obtain a cooking material;

the remaining steps were the same as in example 10.

Comparative example

Comparative example 1

The component content of the plant anti-dandruff shampoo of this comparative example is the same as in example 4;

the extraction method of the traditional Chinese medicine composition extract of the comparative example comprises the following steps:

s3: adding the steamed material, the artemisia leaf, the dandelion, the phellodendron bark, the Chinese honeylocust fruit, the liquorice and the mint powder into a steaming pot, adding 18.5kg of deionized water and ethanol with equal amount, mixing and stirring uniformly, heating to 70 ℃ for steaming, keeping the temperature for 24 hours, taking out of the pot, and putting into an oil press after taking out of the pot to obtain juice;

s4: and (3) placing the material juice into a vacuum distillation kettle, distilling out ethanol in the material juice at the temperature below 70 ℃, standing the distilled material juice, and filtering to obtain transparent liquid, namely the traditional Chinese medicine composition extract.

The preparation method of the plant anti-dandruff shampoo of this comparative example is the same as that of example 4.

Performance test

Detection method

1. Dandruff collecting method

In order to evaluate the therapeutic effect of the extract of the present Chinese medicinal composition, data were collected as follows:

460 volunteers with serious dandruff are selected, the ages of 20-40 years, wherein 230 men and 230 women keep the hair length in the original habit of each person. Each volunteer washed his/her hair at 22 points every 1 day, and then collected with a comb of dense teeth at three time points (7:00, 17:00, 21:50, respectively) within a day, six total dandruff collections per person after each hair washing, and the six collected dandruff collections were combined and weighed as the dandruff value for that volunteer.

(1) Blank group

Each volunteer washes his/her hair with a non-anti-dandruff shampoo, and the value of the dandruff per washing is recorded, and when the value of the dandruff stabilizes at a certain value, this value is taken as the value of the blank dandruff of the volunteer, in g.

(2) Experimental group

460 volunteers were divided into 23 groups of 10 men and 10 women at random, and then 1-23 groups were each recorded with the plant anti-dandruff shampoo of examples 1-22 and comparative example 1, respectively, and each volunteer of each group had a dandruff value in g.

(3) Calculating the average dandruff value

Calculating the blank dandruff value of each group of volunteers according to the blank dandruff value of each group of volunteers; from the dandruff values of each volunteer of each group, the average human dandruff value of each volunteer of each group was calculated as shown in fig. 1.

Each volunteer evaluation test is selected to be carried out in the same time period and the same region, so that season and region climate interference is avoided.

2. Furfural substance content detection method

The furfural substances in the extracting solution of the traditional Chinese medicine composition mainly comprise furfural and 5-hydroxymethylfurfural, and the content of the 5-hydroxymethylfurfural is used for representing the content of the furfural substances in the extracting solution of the traditional Chinese medicine composition.

Preparing a standard sample: preparing 5 groups of 5-hydroxymethylfurfural standard samples, wherein the concentration of the 5 groups of standard samples is 100mg/L, 200mg/L, 500mg/L, 1000mg/L and 2000mg/L respectively;

establishing a standard curve: and (3) injecting a standard sample into a liquid chromatograph, recording a chromatogram, carrying out linear regression by taking the peak area as an ordinate and taking the concentration as an abscissa, and drawing a standard curve.

Taking a proper amount of the traditional Chinese medicine composition extracting solutions of examples 1-22 and comparative example, respectively performing liquid chromatography detection, and calculating the content of 5-hydroxymethylfurfural according to a standard curve, wherein the unit is mg/L, as shown in figure 2.

3. Ethanol content detection method

100mL of fermentation liquid is taken and filtered, an alcohol meter is vertically placed into the filtrate at 20 ℃, and after the alcohol meter is stabilized, the reading is the ethanol content, and the unit is shown in figure 3.

Analysis of results

The anti-dandruff effect of the plant anti-dandruff shampoo is mainly related to the content of active ingredients in the extract of the traditional Chinese medicine composition, and the content of the active ingredients is related to the extraction method.

In the embodiment, the extraction of the traditional Chinese medicine comprises a fermentation process, and in the comparative example 1, the extraction is directly performed by adopting an ethanol extraction method, and as can be seen from fig. 1 and 2, the obtained traditional Chinese medicine has low active ingredients and poor sterilization effect.

In analysis examples 1 to 3, when the content of the extract of the Chinese medicinal composition was the same, the content of the other components in the shampoo was increased, and the anti-dandruff effect was slightly enhanced, but the change was not large.

Analytical examples 3-5, when the content of the extract of the Chinese medicinal composition in the shampoo formulation was increased, the content of the active ingredient in the shampoo was increased, and the anti-dandruff effect of the shampoo was enhanced, but when the content reached a certain value, the content was increased again, and the anti-dandruff effect remained substantially unchanged.

Analysis examples 4, 6 and 7, when the content of each component in the Chinese medicinal composition was increased, the content of the active ingredient was increased, and the anti-dandruff effect was enhanced, but when a certain value was reached, the anti-dandruff effect remained substantially unchanged.

Analysis examples 6 and 8-10, when a Lewis acid catalyst was added in the preparation of the extract of the Chinese medicinal composition, the amount of ethanol produced was increased, the content of the active ingredient was increased, and the anti-dandruff effect was enhanced.

Analytical examples 10-12, the anti-dandruff effect became better with increasing catalyst content, but remained essentially unchanged when the catalyst content reached a certain value.

The present embodiment is merely illustrative of the present application and is not intended to be limiting, and those skilled in the art, after having read the present specification, may make modifications to the present embodiment without creative contribution as required, but is protected by patent laws within the scope of the claims of the present application.

Claims

1. The plant anti-dandruff shampoo is characterized in that: comprises the following components in percentage by weight: 14.25-15.75% of ethoxylated alkyl sodium sulfate, 2.85-3.15% of fatty alcohol ammonium sulfate, 2.38-2.63% of coconut fatty acid diethanolamide, 0.19-0.21% of cationic guar gum, 0.76-0.84% of polyquaternium, 0.5-2.0% of traditional Chinese medicine composition extract, 2.85-3.15% of emulsified silicone oil, 0.19-0.21% of sodium benzoate, 0.11-0.13% of citric acid, 0.48-0.53% of sodium chloride, 0.38-0.42% of essence and the balance of deionized water;

s2: uniformly mixing the crushed dog tail grass ears, the modified Lewis acid catalyst and water, and steaming to obtain a steamed material; the weight ratio of the grass ear powder of the dog tail to the modified Lewis acid catalyst is (34-75) 1;

the modification method of the Lewis acid catalyst comprises the following steps:

1) Respectively weighing 0.5-0.8 part of high molecular hydrogel and 0.05-0.08 part of Lewis acid catalyst, dissolving in water, drying and grinding to obtain powder; the Lewis acid catalyst is one or more of aluminum chloride, ferric chloride and zinc chloride;

3) Respectively weighing 1.7-2.6 parts of polymer hydrogel and 0.34-0.51 part of Lewis acid catalyst, dissolving in water, adding intermediate materials, rapidly and uniformly stirring, drying and grinding; the polymer hydrogel is one or more of agarose, guar gum and carrageenan;

s3: cooling the steamed material, adding distiller's yeast, stirring uniformly, fermenting, and performing condensation reflux operation in the fermentation process for 5 days to obtain a fermented material;

s4: mixing the crushed folium artemisiae argyi, dandelion, phellodendron, chinese honeylocust fruit, liquorice and mint with the fermented material, adding water, uniformly stirring, steaming, performing condensation reflux operation in the steaming process, and juicing after steaming to obtain juice;

2. A method for preparing the plant anti-dandruff shampoo according to claim 1, wherein: according to the formula, respectively weighing ethoxylated alkyl sodium sulfate, fatty alcohol ammonium sulfate, coconut fatty acid diethanolamide, cationic guar gum, polyquaternium-10, traditional Chinese medicine composition extract, emulsified silicone oil, sodium benzoate, citric acid, sodium chloride, essence and deionized water, mixing, and stirring uniformly.