CN116437912A - 自噬激活剂 - Google Patents

自噬激活剂 Download PDF

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Publication number
CN116437912A
CN116437912A CN202180075902.XA CN202180075902A CN116437912A CN 116437912 A CN116437912 A CN 116437912A CN 202180075902 A CN202180075902 A CN 202180075902A CN 116437912 A CN116437912 A CN 116437912A
Authority
CN
China
Prior art keywords
gene
autophagy
salt
ascorbic acid
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180075902.XA
Other languages
English (en)
Chinese (zh)
Inventor
中上夕子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resonac Corp
Original Assignee
Resonac Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Resonac Corp filed Critical Resonac Corp
Publication of CN116437912A publication Critical patent/CN116437912A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202180075902.XA 2020-09-17 2021-09-17 自噬激活剂 Pending CN116437912A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-156457 2020-09-17
JP2020156457 2020-09-17
PCT/JP2021/034211 WO2022059763A1 (ja) 2020-09-17 2021-09-17 オートファジー活性化剤

Publications (1)

Publication Number Publication Date
CN116437912A true CN116437912A (zh) 2023-07-14

Family

ID=80776039

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180075902.XA Pending CN116437912A (zh) 2020-09-17 2021-09-17 自噬激活剂

Country Status (5)

Country Link
JP (1) JPWO2022059763A1 (https=)
KR (1) KR20230051238A (https=)
CN (1) CN116437912A (https=)
TW (1) TW202228676A (https=)
WO (1) WO2022059763A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06271466A (ja) * 1993-03-23 1994-09-27 Asahi Chem Ind Co Ltd 神経成長因子活性増強剤
CN1658864A (zh) * 2002-04-12 2005-08-24 昭和电工株式会社 稳定的抗坏血酸衍生物
KR20170025604A (ko) * 2015-08-31 2017-03-08 연세대학교 원주산학협력단 아스코르브산 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 퇴행성 신경질환 치료용 약학적 조성물
JP2019011254A (ja) * 2017-06-29 2019-01-24 ちふれホールディングス株式会社 表皮肥厚抑制剤
JP2019081718A (ja) * 2017-10-30 2019-05-30 日光ケミカルズ株式会社 ヒアルロン酸合成酵素発現促進剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013018779A1 (ja) 2011-08-01 2013-02-07 株式会社林原 α－グルコシルヘスペリジンの結晶とその用途
JP6018800B2 (ja) * 2012-05-25 2016-11-02 ライオン株式会社 経口投与組成物
KR20170141705A (ko) 2015-04-08 2017-12-26 바이오멘딕스, 엘엘씨 상처 치유를 조절하기 위한 제형 및 방법
JP6740354B2 (ja) 2015-10-05 2020-08-12 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク オートファジーの流れ及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
JP7136765B2 (ja) 2017-03-24 2022-09-13 株式会社林原 オートファジー誘導剤とその用途
JP7497850B2 (ja) * 2019-12-23 2024-06-11 株式会社アイ・ティー・オー 細胞送達用キャリア

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06271466A (ja) * 1993-03-23 1994-09-27 Asahi Chem Ind Co Ltd 神経成長因子活性増強剤
CN1658864A (zh) * 2002-04-12 2005-08-24 昭和电工株式会社 稳定的抗坏血酸衍生物
KR20170025604A (ko) * 2015-08-31 2017-03-08 연세대학교 원주산학협력단 아스코르브산 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 퇴행성 신경질환 치료용 약학적 조성물
JP2019011254A (ja) * 2017-06-29 2019-01-24 ちふれホールディングス株式会社 表皮肥厚抑制剤
JP2019081718A (ja) * 2017-10-30 2019-05-30 日光ケミカルズ株式会社 ヒアルロン酸合成酵素発現促進剤

Also Published As

Publication number Publication date
TW202228676A (zh) 2022-08-01
JPWO2022059763A1 (https=) 2022-03-24
KR20230051238A (ko) 2023-04-17
WO2022059763A1 (ja) 2022-03-24

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Application publication date: 20230714