CN116249712A - Tau结合化合物 - Google Patents

Tau结合化合物 Download PDF

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Publication number
CN116249712A
CN116249712A CN202180042110.2A CN202180042110A CN116249712A CN 116249712 A CN116249712 A CN 116249712A CN 202180042110 A CN202180042110 A CN 202180042110A CN 116249712 A CN116249712 A CN 116249712A
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amino acid
seq
antibody
sequence
acid sequence
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Chinese (zh)
Inventor
T·卡特
侯金兆
V·库雷拉
A·D·卡皮利
W·刘
H·Y·钟
J·霍尔特
D·卡瓦纳
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Voyager Therapeutics Inc
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Voyager Therapeutics Inc
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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CN202180042110.2A 2020-04-15 2021-04-14 Tau结合化合物 Pending CN116249712A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063010261P 2020-04-15 2020-04-15
US63/010,261 2020-04-15
US202163162976P 2021-03-18 2021-03-18
US63/162,976 2021-03-18
PCT/US2021/027346 WO2021211753A1 (en) 2020-04-15 2021-04-14 Tau binding compounds

Publications (1)

Publication Number Publication Date
CN116249712A true CN116249712A (zh) 2023-06-09

Family

ID=75787309

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180042110.2A Pending CN116249712A (zh) 2020-04-15 2021-04-14 Tau结合化合物

Country Status (11)

Country Link
US (1) US20230192830A1 (https=)
EP (1) EP4135841A1 (https=)
JP (2) JP7713956B2 (https=)
KR (1) KR20230020394A (https=)
CN (1) CN116249712A (https=)
AU (1) AU2021257848A1 (https=)
BR (1) BR112022020753A2 (https=)
CA (1) CA3180222A1 (https=)
IL (1) IL297200A (https=)
MX (1) MX2022012752A (https=)
WO (1) WO2021211753A1 (https=)

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US12180301B2 (en) * 2018-03-06 2024-12-31 Imcare Biotech, Llc Serine protease inhibitor kazal (SPIK) compositions and methods
US12377162B2 (en) 2019-07-08 2025-08-05 Imcare Biotech, Llc Anti-serine protease inhibitor kazal (SPIK) antibodies, immunoconjugates, and methods of use
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
EP4543473A1 (en) 2022-06-22 2025-04-30 Voyager Therapeutics, Inc. Tau binding compounds
KR20250069606A (ko) 2022-09-15 2025-05-19 보이저 테라퓨틱스, 인크. 타우 결합 화합물
CN120018859A (zh) * 2022-10-05 2025-05-16 尚华创新公司 抗尿激酶型纤溶酶原激活物受体抗体及其使用方法
WO2024086747A1 (en) 2022-10-19 2024-04-25 Affinia Therapeutics Inc. Recombinant aavs with improved tropism and specificity
EP4705484A1 (en) 2023-05-03 2026-03-11 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
TW202444917A (zh) * 2023-05-04 2024-11-16 美商航海家醫療公司 Ａａｖ衣殼變異體及其用途
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
WO2025192556A1 (ja) * 2024-03-12 2025-09-18 学校法人 学習院 タウ凝集体に結合する抗体およびその用途

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CN106459188A (zh) * 2014-01-28 2017-02-22 豪夫迈－罗氏公司 针对磷酸化tau蛋白的骆驼科单结构域抗体以及生产其缀合物的方法
CN106659759A (zh) * 2014-06-27 2017-05-10 C2N诊断有限责任公司 人源化抗tau抗体
CN106794244A (zh) * 2014-03-17 2017-05-31 赛诺菲生物技术公司 用于降低心血管风险的方法
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