CN116211934A - Traditional Chinese medicine composition and preparation for treating gout and preparation method thereof - Google Patents

Traditional Chinese medicine composition and preparation for treating gout and preparation method thereof Download PDF

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CN116211934A
CN116211934A CN202310400870.7A CN202310400870A CN116211934A CN 116211934 A CN116211934 A CN 116211934A CN 202310400870 A CN202310400870 A CN 202310400870A CN 116211934 A CN116211934 A CN 116211934A
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孙银明
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Abstract

The invention discloses a traditional Chinese medicine composition for treating gout, a preparation and a preparation method thereof, belonging to the technical field of Chinese herbal medicines. The traditional Chinese medicine composition takes prepared common monkshood mother root, prepared kusnezoff monkshood root, szechuan lovage rhizome, dried rehmannia root, prepared rehmannia root, chinese angelica and cassia twig as principal drugs, mainly takes the main treatment principles of tonifying qi and strengthening spleen, tonifying liver and tonifying kidney, soothing nerves and invigorating yang and qi, replenishing blood and activating blood, regulating menstruation and relieving pain, dispelling wind and removing dampness and relieving pain, and combines the purposes of treating gout and osteoarthropathy by combining notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, acanthopanax root, red paeony root, divaricate saposhnikovia root, large-leaved gentian, parasitic vine, lycopodium clavatum, common clubmoss herb, uncaria and raw fleece-flower root.

Description

Traditional Chinese medicine composition and preparation for treating gout and preparation method thereof
Technical Field
The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a traditional Chinese medicine composition for treating gout, a preparation and a preparation method thereof.
Background
Gouty arthritis is an inflammatory disease of the joints caused by deposition of urate crystals at joints, muscles, ligaments. The main purpose of the current treatment of gouty arthritis is to alleviate disease symptoms, and two main treatment modes exist in the prior art: (1) colchicine, a non-steroidal analgesic: the two medicines can relieve the arthralgia symptoms of partial patients, but can not treat the symptoms and the root causes, and can not treat gouty arthritis fundamentally, and the colchicine and the nonsteroidal analgesic have the problems of large adverse reactions of gastrointestinal tracts and the like, and the colchicine also has adverse reactions of bone marrow suppression and the like, the poisoning amount of the colchicine is often related to the accumulation dose in the bodies, the long-term treatment effect is poor, and the colchicine and the nonsteroidal analgesic cannot be used for patients suffering from respiratory diseases such as asthma, acute cardiovascular diseases and chronic kidney diseases. (2) Glucocorticoids: mainly plays a role in inhibiting inflammatory reaction, but local or systemic application of hormone increases the risk of infection of joint cavities and osteonecrosis.
The theory of traditional Chinese medicine holds that: the gouty arthritis pathogenesis is summarized as the pain caused by congenital endowment deficiency, improper diet, exogenous wind-cold summer-heat dampness-heat dryness six-excessive and seven-emotion internal injury, damp-heat coagulation, long-term accumulation and heat toxin formation, and attack and annotate hands and feet; moreover, wind is a long disease, and is active but not living, and helps damp-heat flow into the whole body, so the disease parts of gouty joints can be seen at the joints of limbs.
At present, the traditional Chinese medicine is mainly used for treating the diseases by using medicines for dispelling wind, relieving exterior syndrome, promoting blood circulation, removing blood stasis, removing dampness and relieving pain, and meanwhile, the formula is extremely complex, the effect is limited, and the traditional Chinese medicine has no function.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating gout, which takes the main treatment principles of replenishing qi to invigorate the spleen, tonifying liver and kidney, soothing the nerves and invigorating yang and transforming qi, enriching blood and activating blood, regulating menstruation and relieving pain, dispelling wind and removing dampness and relieving pain as well as takes prepared radix aconiti, prepared radix aconiti kusnezoffii, ligusticum wallichii, dried rehmannia root, prepared rhizome of rehmannia, chinese angelica and cassia twig as core medicines, and is matched with other raw materials to treat both principal and secondary aspect of the disease, thereby achieving the purpose of treating gout and osteoarticular pain.
The invention is realized by the following technical scheme:
the traditional Chinese medicine composition for treating gout is mainly prepared from the following raw materials in parts by mass:
10-30 parts of ligusticum wallichii, 20-40 parts of notopterygium root, 20-40 parts of radix angelicae pubescentis, 10-20 parts of photinia fraseri, 10-20 parts of frankincense, 10-20 parts of myrrh, 10-30 parts of cassia twig, 20-40 parts of acanthopanax, 10-30 parts of red paeony root, 10-30 parts of radix sileris, 10-30 parts of angelica sinensis, 20-40 parts of large-leaf gentian root, 10-30 parts of herba taxilli, 10-30 parts of dried rehmannia root, 10-30 parts of prepared rehmannia root, 10-20 parts of lycopodium clavatum, 10-20 parts of uncaria, 20-40 parts of raw fleece-flower root, 20-40 parts of prepared radix aconiti and 20-40 parts of prepared radix aconiti kusnezoffii.
The traditional Chinese medicine composition takes prepared common monkshood mother root, prepared kusnezoff monkshood root, szechuan lovage rhizome, dried rehmannia root, prepared rehmannia root, chinese angelica and cassia twig as principal drugs, mainly takes the main treatment principles of tonifying qi and strengthening spleen, nourishing liver and tonifying kidney, soothing nerves and invigorating yang and qi, replenishing blood and activating blood, regulating menstruation and relieving pain, dispelling wind and removing dampness and relieving pain, and combines the purposes of treating gout and osteoarthropathy by combining notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, acanthopanax root, red paeony root, divaricate saposhnikovia root, large-leaved gentian, parasitic vine, lycopodium clavatum, common clubmoss herb and raw fleece-flower root.
Preferably, the traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by mass:
15-25 parts of ligusticum wallichii, 25-35 parts of notopterygium root, 25-35 parts of radix angelicae pubescentis, 12-17 parts of photinia fraseri, 12-17 parts of frankincense, 12-17 parts of myrrh, 15-25 parts of cassia twig, 25-35 parts of acanthopanax, 15-25 parts of red paeony root, 15-25 parts of radix sileris, 15-25 parts of angelica sinensis, 25-35 parts of large-leaf gentian root, 15-25 parts of parasitic vine, 15-25 parts of dried rehmannia root, 15-25 parts of prepared rehmannia root, 12-17 parts of lycopodium clavatum, 12-17 parts of uncaria, 25-35 parts of raw fleece-flower root, 25-35 parts of prepared radix aconiti and 25-35 parts of prepared radix aconiti kusnezoffii.
Preferably, the traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by mass:
20 parts of ligusticum wallichii, 30 parts of notopterygium root, 30 parts of radix angelicae pubescentis, 15 parts of photinia fraseri, 15 parts of frankincense, 15 parts of myrrh, 20 parts of cassia twig, 30 parts of acanthopanax, 20 parts of red paeony root, 20 parts of radix sileris, 20 parts of angelica sinensis, 30 parts of large-leaf gentian root, 20 parts of parasitic vine, 20 parts of radix rehmanniae, 20 parts of prepared rehmannia root, 15 parts of lycopodium clavatum, 15 parts of uncaria, 30 parts of raw fleece-flower root, 30 parts of prepared radix aconiti and 30 parts of prepared radix aconiti kusnezoffii.
Ligusticum wallichii, the name of Chinese traditional medicine, is the dried rhizome of Ligusticum wallichii Ligusticum chuanxiong Hort, a plant of Ligusticum of Umbelliferae. Has effects of promoting blood circulation, activating qi-flowing, dispelling pathogenic wind, and relieving pain. Is mainly used for treating chest stuffiness and pain due to heart vessel stasis, hypochondrium distending pain due to liver depression and qi stagnation, chest stuffiness and pain due to liver blood stasis, traumatic injury due to blood stasis, sore and ulcer, irregular menstruation, amenorrhea and dysmenorrhea, postpartum stagnant pain, lochia, various headaches, rheumatalgia and the like. Pungent taste and warm nature; enter liver, gallbladder and pericardium meridians.
Notopterygium root, rhizoma Et radix Notopterygium, chinese medicine name. Is root and stem of Notopterygium incisum Notopterygium incisum Ting ex H.T.Chang or Notopterygium forbesii Notopterygium forbesii Boiss. Has effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, eliminating dampness, and relieving pain. It is used for treating common cold due to wind-cold and arthralgia due to wind-cold-dampness. Pungent and bitter in taste and warm in nature; enter bladder and kidney meridians.
Radix Angelicae Pubescentis, the name of Chinese medicine. Is dry root of Angelica sinensis (L.) Diels Angelica pubescens Maxim.f. bisearate Shan et Yuan of Angelica genus of Umbelliferae. Has effects of dispelling pathogenic wind and removing dampness, relieving pain, and relieving exterior syndrome. It is used for treating arthralgia due to wind-cold-dampness, exterior syndrome due to wind-cold-dampness, headache due to shaoyin, and skin pruritus. Pungent and bitter in taste and slightly warm in nature; enter kidney and bladder meridians.
Photinia fraseri is a climbing vine of the family Piperaceae of the genus Piperaceae. It is neutral in nature and pungent and bitter in flavor. Enter kidney meridian. Has effects of dispelling pathogenic wind, removing dampness, relaxing muscles and tendons, strengthening waist, relieving arthralgia, and relieving pain. Can be used for treating arthralgia and myalgia, arthralgia due to wind-cold-dampness, lumbago, skelalgia, weakness, cough due to kidney deficiency, sexual impotence, cough, asthma, dysuria, early stage of stranguria due to heat, rheumarthritis, common cold due to wind-cold, infantile malnutrition, abdominal distention, sore pain, etc. In addition, photinia serrulata also has the effect of invigorating stomach.
Olibanum and Chinese medicine. Is resin exuded from bark of olibanum tree Boswellia carterii birdw of olibanum of Oleraceae. Has effects of promoting blood circulation, activating qi-flowing, relieving pain, detumescence and promoting granulation. Is mainly used for promoting blood circulation, promoting qi circulation, relieving pain, detumescence, promoting granulation, and relieving pain due to qi stagnation and blood stasis. Pungent and bitter in taste and warm in nature; it enters heart, liver and spleen meridians.
Has no fragrance, pungent and bitter properties and is flat. It enters heart, liver and spleen meridians. Myrrh efficacy and application: promoting blood circulation, relieving pain, detumescence and promoting granulation. Can be used for treating traumatic injury, pain due to stasis, carbuncle, swelling and pain, ulcer, and pain due to stasis. The difference is that the frankincense is more suitable for promoting qi circulation and stretching tendons and is used for treating arthralgia. Myrrh is better at dispelling blood stasis and resolving stasis, and is indicated for stomach ache with serious blood stasis and qi stagnation.
Ramulus Cinnamomi, the name of Chinese medicine. Is the tender branch of cinnamon Cinnamomum cassia Presl of Cinnamomum of Lauraceae. Has effects of inducing sweat, relieving muscle, warming and activating meridian, and supporting yang and activating qi-flowing. It is mainly used for treating common cold due to wind-cold, pain due to congealing cold and blood stagnation, phlegm retention, water retention and palpitation. Pungent and sweet in taste and warm in nature; it enters heart, lung and bladder meridians.
Acanthopanax root and its Chinese medicine name. Is rhizome or stem of Acanthopanax senticosus Acantha panax senticosus (rupr. Et maxim) H arms of Acanthopanax of Araliaceae. Has effects of invigorating qi, invigorating spleen, tonifying kidney, and tranquilizing. Is mainly used for treating spleen and lung qi deficiency, kidney deficiency, soreness of waist and knees, heart and spleen deficiency, insomnia, amnesia and the like. Sweet in taste and slightly bitter in nature; it enters spleen, lung, heart and kidney meridians.
Red peony root, chinese medicine name. Is dry root of Paeonia lactiflora Paeonia lactiflora pall or Paeonia lactiflora P.veitchii Lynch. Has effects of clearing heat, cooling blood, promoting blood circulation, and removing blood stasis. Is mainly used for treating toxic heat with symptoms of macula, hematemesis, epistaxis, conjunctival congestion, swelling and pain, carbuncle, swelling and sore, liver Yu Xie pain, amenorrhea, dysmenorrhea, abdominal mass, abdominal pain and traumatic injury. Bitter taste and slightly cold nature; enter liver meridian.
Radix Saposhnikoviae, and Chinese medicinal herbs. Is root of Ledebouriella plant of Ledebouriella of Umbelliferae Saposhnikovia divaricata (Turcz.) Schischk. Has effects of dispelling pathogenic wind, relieving exterior syndrome, eliminating dampness, relieving pain, and relieving spasm. It is mainly used for treating exterior syndrome of exogenous pathogenic factor, rubella pruritus, rheumatalgia and tetanus. Pungent and sweet in taste and slightly warm in nature; it enters bladder and liver meridians.
Angelica, chinese medicine name. Is root of Angelica sinensis Angelica sinensis (Oliv) Diels. Has effects of replenishing blood, regulating menstruation, promoting blood circulation, relieving pain, loosening bowel, and relieving constipation. Is mainly used for treating blood deficiency and sallow complexion, irregular menstruation, amenorrhea and dysmenorrhea, blood deficiency, blood stagnation, blood cold pain, traumatic injury, rheumatalgia, carbuncle, sore and ulcer, constipation due to intestinal dryness, etc. Sweet and pungent taste and warm nature; it enters liver, heart and spleen meridians.
Gentiana macrophylla and Chinese medicine. Is dry root of Gentiana macrophylla (Gentiana macrophylla, gentiana macrophylla. Mu.lla pall.) of Gentiana of Gentianaceae, gentiana macrophylla Gentiana straminea maxim. Of Gentiana, gentiana macrophylla, gentiana crassicaulis Duthie ex Burk. Or Gentiana microphylla Gentiana dahurica Fisch. Of Gentiana. Has effects of dispelling pathogenic wind and dampness, dredging collaterals, relieving pain, removing deficiency heat, and clearing damp heat. Is mainly used for treating apoplexy, hectic fever due to bone steaming, infantile malnutrition fever, and jaundice due to damp-heat. Pungent and bitter in taste and mild in nature; it enters stomach, liver and gallbladder meridians.
Herba Taxilli, and its name. Is a whole plant of Danser of the genus Taxilli of the family Santalaceae, genus Taxilli Dendrotrophe frutescens (Champ. Ex benth.). Has effects of dispelling blood, relieving swelling, and relieving pain. Is mainly used for treating incised wound and traumatic injury. Slightly sweet, bitter and astringent in taste, and flat in nature; enter the lung and liver meridians.
Dried rehmannia root, taste: fresh rehmannia root: sweet, bitter and cold. Radix rehmanniae: sweet and cold. Prepared rehmannia root: sweet and slightly warm. Channel tropism: it enters heart, liver and kidney meridians. The main functions are as follows: rehmannia root is cool in nature and sweet and bitter in taste, and has the effects of nourishing yin, tonifying kidney, nourishing blood, enriching blood and cooling blood. It is beneficial to people with deficiency of yin and blood and kidney. In addition, rehmannia has the effects of strengthening heart, promoting urination, relieving fever, diminishing inflammation, promoting blood coagulation and reducing blood sugar. Clear heat and cool blood, nourish yin and promote the production of body fluid. Can be used for treating pyretic diseases, deep-red tongue, polydipsia, yin deficiency, internal heat, bone steaming, internal heat, diabetes, hematemesis, epistaxis, and macula.
Prepared rehmannia root, radix rehmanniae Preparata, having effects of nourishing yin and blood, replenishing vital essence and replenishing marrow. Can be used for treating deficiency of liver-yin and kidney-yin, soreness of waist and knees, hectic fever due to bone steaming, night sweat, spermatorrhea, internal heat, diabetes, blood deficiency, sallow complexion, palpitation, menoxenia, metrorrhagia, blood stasis, dizziness, tinnitus, and premature graying of hair and beard.
Lycopodium clavatum, chinese medicine name. Is dried whole plant of Pinus koraiensis Lycopodium jaPonicum thunder. Harvesting in summer and autumn when the stem and leaf are luxuriant, removing impurities, and sun drying. Has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles and activating collaterals. Can be used for treating joint pain and difficulty in flexing and extending. Bitter and slightly pungent taste and warm nature; it enters liver, spleen and kidney meridians.
Herba Lycopodii and its name. Is whole plant of Pinus sylvestris Lycopodiastrum casuarinoides (Spring) Holub [ Lycopodium casuarinoides Spring ] of Pinus genus of Pinaceae. Has effects of dispelling pathogenic wind, removing dampness, relaxing muscles and tendons, promoting blood circulation, improving eyesight, and removing toxic substances. Can be used for treating rheumatalgia, lumbar muscle strain, hand and foot failure after injury of tendons, menoxenia, night sweat, conjunctivitis, night blindness, scald due to water and fire, and pyocutaneous disease. Slightly sweet in flavor and neutral in nature.
Ramulus Uncariae cum Uncis, and Chinese medicinal materials. Is a hooked stem branch of Uncaria rhynchophylla 0 phyla (Miq.) of Uncaria genus of Rubiaceae family, jacks, uncaria macrophylla Uncaria macrophylla wall, uncaria tomentosa Havill, uncaria sinensis (Oliv.) or Uncaria sessilis Uncaria sessilifructus Roxb. Has effects of clearing heat, suppressing hyperactive liver, calming endogenous wind and relieving spasm. Is mainly used for treating liver wind internal stirring, convulsion and epilepsy; headache and dizziness due to liver fire attacking upwards or liver yang hyperactivity; headache with wind-heat exterior syndrome, conjunctival congestion, macula, and other symptoms. Sweet in taste and slightly cold in nature; enter liver and pericardium meridians.
Radix Polygoni Multiflori, with effects of removing toxic substances, resolving carbuncle, loosening bowel to relieve constipation, is often used for treating scrofula, carbuncle, rubella, pruritus and constipation due to intestinal dryness; fleece-flower root has the functions of tonifying liver and kidney, replenishing essence and blood and strengthening tendons and bones. The famous anti-aging prescription of 'shou Wu Yan shou Wan' and 'Qibaomen Wan' is prepared by taking shou Wu as a main medicine. The fleece-flower root can improve the aging symptoms of the aged, such as white hair, tooth fall, senile plaque and the like, promote the immunity of the human body and inhibit the deposition of lipofuscin which can cause the aging of the human body in body organs. The fleece-flower root also can dilate coronary artery blood vessels of heart, reduce blood fat and promote erythropoiesis, so that the fleece-flower root has a preventive effect on coronary heart disease, hyperlipidemia, senile anemia, cerebral degeneration, presenility and the like.
Radix Aconiti Preparata, the name of Chinese medicine. Is processed product of radix Aconiti. Has effects of dispelling pathogenic wind, removing dampness, warming channels and relieving pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, cold hernia pain, and anesthesia and pain. Pungent and bitter in flavor and warm in nature. Heart, liver, kidney and spleen meridians.
Radix Aconiti Kusnezoffii Preparata, and Chinese medicine. Is processed product of radix aconiti kusnezoffii. Mainly produce Shanxi, hebei, inner Mongolia and northeast. Has effects in dispelling pathogenic wind, removing dampness, warming channel, and relieving pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, and cold hernia. Pungent and bitter in flavor and warm in nature. Heart, liver, kidney and spleen meridians.
A formulation for treating gout, the formulation comprising a traditional Chinese medicine composition.
Preferably, the formulation is an oral formulation.
A method for preparing a preparation for treating gout, comprising:
selecting all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, uncaria, radix polygoni multiflori, prepared radix aconiti and prepared radix aconiti kusnezoffii according to corresponding parts by weight, mixing, and adding white wine for soaking.
Preferably, the ethanol content in the white spirit is 60wt%.
Preferably, the volume ratio of the mixed raw materials to the white spirit is 460 g: 3-5 jin.
Preferably, the soaking time period is not less than 5 days.
Compared with the prior art, the invention has at least the following technical effects:
the invention provides a traditional Chinese medicine composition for treating gout, which takes prepared common monkshood mother root, prepared kusnezoff monkshood root, szechuan lovage rhizome, dried rehmannia root, prepared rehmannia root, chinese angelica and cassia twig as principal drugs, takes the main treatment principles of tonifying qi and spleen, nourishing liver and tonifying kidney, soothing nerves and invigorating yang and qi, replenishing blood and activating blood, regulating menstruation and relieving pain, dispelling wind and removing dampness and relieving pain, and combines the main treatment principles of notopterygium root, pubescent angelica root, photinia fraseri, frankincense, myrrh, acanthopanax root, red paeony root, divaricate saposhnikovia root, large-leaved gentian, parasitic vine, lycopodium clavatum, common clubmoss herb, common hooked uncaria and raw fleece-flower root to treat both principal and secondary aspect of disease, so as to achieve the aim of treating gout and osteoarthritic pain.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the following examples, which are to be construed as merely illustrative and not limitative of the scope of the invention, but are not intended to limit the scope of the invention to the specific conditions set forth in the examples, either as conventional or manufacturer-suggested, nor are reagents or apparatus employed to identify manufacturers as conventional products available for commercial purchase.
Example 1:
the traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight:
10 g of ligusticum wallichii, 20g of notopterygium root, 20g of radix angelicae pubescentis, 10 g of photinia fraseri, 10 g of frankincense, 10 g of myrrh, 10 g of cassia twig, 20g of acanthopanax, 10 g of red paeony root, 10 g of radix sileris, 10 g of angelica sinensis, 20g of large-leaf gentian root, 10 g of parasitic vine, 10 g of radix rehmanniae, 10 g of prepared rehmannia root, 10 g of lycopodium clavatum, 10 g of uncaria, 20g of raw fleece-flower root, 20g of prepared radix aconiti and 20g of prepared radix aconiti kusnezoffii.
A method for preparing a preparation for treating gout, comprising:
according to the corresponding parts by weight, all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, radix polygoni multiflori, raw fleece-flower root, prepared radix aconiti and prepared radix aconiti kusnezoffii are mixed, and then added with 420kg of 60-degree white spirit to be soaked for 5 days.
Example 2:
the traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight:
30 g of ligusticum wallichii, 40 g of notopterygium root, 40 g of radix angelicae pubescentis, 20g of photinia fraseri, 20g of frankincense, 20g of myrrh, 30 g of cassia twig, 40 g of acanthopanax, 30 g of red paeony root, 30 g of radix sileris, 30 g of angelica sinensis, 40 g of large-leaf gentian root, 30 g of parasitic vine, 30 g of radix rehmanniae, 30 g of prepared rehmannia root, 20g of lycopodium clavatum, 20g of uncaria, 40 g of raw fleece-flower root, 40 g of prepared radix aconiti and 40 g of prepared radix aconiti kusnezoffii.
A method for preparing a preparation for treating gout, comprising:
selecting all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, radix polygoni multiflori preparata, radix aconiti preparata and radix aconiti kusnezoffii preparata according to the corresponding parts by weight, mixing, adding 960kg of 60-degree white spirit, and soaking for 5 days.
Example 3:
the traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight:
15 g of ligusticum wallichii, 25 g of notopterygium root, 25 g of radix angelicae pubescentis, 12 g of photinia fraseri, 12 g of frankincense, 12 g of myrrh, 15 g of cassia twig, 25 g of acanthopanax, 15 g of red paeony root, 15 g of radix sileris, 15 g of angelica sinensis, 25 g of large-leaf gentian root, 15 g of parasitic vine, 15 g of radix rehmanniae, 15 g of prepared rehmannia root, 12 g of lycopodium clavatum, 12 g of uncaria, 25 g of raw fleece-flower root, 25 g of prepared radix aconiti and 25 g of prepared radix aconiti kusnezoffii.
A method for preparing a preparation for treating gout, comprising:
selecting all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, radix polygoni multiflori preparata, radix aconiti preparata and radix aconiti kusnezoffii preparata according to the corresponding parts by weight, mixing, adding 550.5kg of 60-degree white spirit, and soaking for 5 days.
Example 4:
the traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight:
25 g of szechuan lovage rhizome, 35 g of notopterygium root, 35 g of pubescent angelica root, 17 g of photinia, 17 g of frankincense, 17 g of myrrh, 25 g of cassia twig, 35 g of acanthopanax, 25 g of red paeony root, 25 g of divaricate saposhnikovia root, 25 g of Chinese angelica, 35 g of large-leaf gentian root, 25 g of parasitic vine, 25 g of dried rehmannia root, 25 g of prepared rehmannia root, 17 g of lycopodium clavatum, 17 g of uncaria, 35 g of raw fleece-flower root, 35 g of prepared common monkshood mother root and 35 g of prepared kusnezoff monkshood root.
A method for preparing a preparation for treating gout, comprising:
selecting all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, radix polygoni multiflori preparata, radix aconiti preparata and radix aconiti kusnezoffii preparata according to the corresponding parts by weight, mixing, adding 820.5kg of 60-degree white spirit, and soaking for 5 days.
Example 5:
the traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight:
20g of ligusticum wallichii, 30 g of notopterygium root, 30 g of radix angelicae pubescentis, 15 g of photinia fraseri, 15 g of frankincense, 15 g of myrrh, 20g of cassia twig, 30 g of acanthopanax, 20g of red paeony root, 20g of radix sileris, 20g of angelica sinensis, 30 g of large-leaf gentian root, 20g of parasitic vine, 20g of radix rehmanniae, 20g of prepared rehmannia root, 15 g of lycopodium clavatum, 15 g of uncaria, 30 g of raw fleece-flower root, 30 g of prepared radix aconiti and 30 g of prepared radix aconiti kusnezoffii.
A method for preparing a preparation for treating gout, comprising:
selecting all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, radix polygoni multiflori preparata, radix aconiti preparata and radix aconiti kusnezoffii preparata according to the corresponding parts by weight, mixing, and adding 690kg of 60-degree white spirit and soaking for 5 days.
The using mode is as follows: the oral administration is carried out for 1 time/day, the dosage is not more than 20 g/day, and the oral administration is carried out after dinner. Can be applied according to the guiding dosage under guidance.
If the medicine can not be taken orally or applied externally, the medicine can be used for wiping the painful parts for 2-3 times a day for 30-35min each time, and absorption is promoted.
Taboo: it is forbidden to alcohol allergy patients, and has adverse reaction during treatment, and should be suspended.
The medicated liquor can not be mixed with western medicines for use;
disabling ischemic and hematopoietic dysfunction.
Clinical cases:
patient 1: some person will get gout for 5 years. After taking the medicinal liquor prepared in the embodiment 5 for one and a half months, various indexes of gout tend to be normal.
Patient 2: some of the joints are blocked by the movement of the neck, hands and feet caused by cerebral infarction. After taking the medicinal liquor prepared in the embodiment 5 for 7 days, various indexes are obviously improved.
Patient 3: some stone, cervical vertebra and lumbar vertebra degeneration type pain caused by the venereal disease. After taking the medicinal liquor prepared in the embodiment 5 for 7 days, various indexes are obviously improved.
Finally, it should be noted that: the foregoing description is only of the preferred embodiments of the invention and is not intended to limit the scope of the invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (9)

1. The traditional Chinese medicine composition for treating gout is characterized by being prepared from the following raw materials in parts by weight:
10-30 parts of ligusticum wallichii, 20-40 parts of notopterygium root, 20-40 parts of radix angelicae pubescentis, 10-20 parts of photinia fraseri, 10-20 parts of frankincense, 10-20 parts of myrrh, 10-30 parts of cassia twig, 20-40 parts of acanthopanax, 10-30 parts of red paeony root, 10-30 parts of radix sileris, 10-30 parts of angelica sinensis, 20-40 parts of large-leaf gentian root, 10-30 parts of herba taxilli, 10-30 parts of dried rehmannia root, 10-30 parts of prepared rehmannia root, 10-20 parts of lycopodium clavatum, 10-20 parts of uncaria, 20-40 parts of raw fleece-flower root, 20-40 parts of prepared radix aconiti and 20-40 parts of prepared radix aconiti kusnezoffii.
2. The traditional Chinese medicine composition for treating gout according to claim 1, wherein the traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight:
15-25 parts of ligusticum wallichii, 25-35 parts of notopterygium root, 25-35 parts of radix angelicae pubescentis, 12-17 parts of photinia fraseri, 12-17 parts of frankincense, 12-17 parts of myrrh, 15-25 parts of cassia twig, 25-35 parts of acanthopanax, 15-25 parts of red paeony root, 15-25 parts of radix sileris, 15-25 parts of angelica sinensis, 25-35 parts of large-leaf gentian root, 15-25 parts of parasitic vine, 15-25 parts of dried rehmannia root, 15-25 parts of prepared rehmannia root, 12-17 parts of lycopodium clavatum, 12-17 parts of uncaria, 25-35 parts of raw fleece-flower root, 25-35 parts of prepared radix aconiti and 25-35 parts of prepared radix aconiti kusnezoffii.
3. The traditional Chinese medicine composition for treating gout according to claim 1, wherein the traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight:
20 parts of ligusticum wallichii, 30 parts of notopterygium root, 30 parts of radix angelicae pubescentis, 15 parts of photinia fraseri, 15 parts of frankincense, 15 parts of myrrh, 20 parts of cassia twig, 30 parts of acanthopanax, 20 parts of red paeony root, 20 parts of radix sileris, 20 parts of angelica sinensis, 30 parts of large-leaf gentian root, 20 parts of parasitic vine, 20 parts of radix rehmanniae, 20 parts of prepared rehmannia root, 15 parts of lycopodium clavatum, 15 parts of uncaria, 30 parts of raw fleece-flower root, 30 parts of prepared radix aconiti and 30 parts of prepared radix aconiti kusnezoffii.
4. A formulation for treating gout, comprising the traditional Chinese medicine composition according to any one of claims 1 to 3.
5. A formulation for treating gout according to claim 4, wherein the formulation is an oral formulation.
6. A method of preparing a formulation for treating gout according to claim 4 or 5, comprising:
selecting all raw materials of ligusticum wallichii, notopterygium root, radix angelicae pubescentis, photinia fraseri, frankincense, myrrh, cassia twig, acanthopanax root, radix paeoniae rubra, radix sileris, angelica sinensis, large-leaf gentian root, herba taxilli, dried rehmannia root, prepared rhizome of rehmannia, lycopodium clavatum, uncaria, radix polygoni multiflori, prepared radix aconiti and prepared radix aconiti kusnezoffii according to corresponding parts by weight, mixing, and adding white wine for soaking.
7. The method for preparing a preparation for treating gout according to claim 6, wherein the ethanol content in the white spirit is 60wt%.
8. The method for preparing a preparation for treating gout according to claim 6, wherein the volume ratio of the mixed raw materials to the white spirit is 460 g: 3-5 jin.
9. The method for preparing a formulation for treating gout according to claim 6, wherein the soaking time period is not less than 5 days.
CN202310400870.7A 2023-04-14 2023-04-14 Traditional Chinese medicine composition and preparation for treating gout and preparation method thereof Pending CN116211934A (en)

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Publication number Priority date Publication date Assignee Title
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CN106581599A (en) * 2015-10-15 2017-04-26 贵州瑞和制药有限公司龙里药厂 Drug for treating rheumatism and preparation method thereof
CN108619478A (en) * 2018-07-13 2018-10-09 魏明辉 A kind of Chinese medicine preparation for treating treating rheumatic ostealgia
CN109498699A (en) * 2018-12-28 2019-03-22 宋永盛 A kind of liquid medicine and preparation method thereof for treating rheumatic and rheumatoid
CN109985210A (en) * 2019-04-30 2019-07-09 内蒙古云家老太健康管理服务有限公司 A kind of Chinese medicine composition and preparation method thereof for treating treating rheumatic ostealgia

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1425395A (en) * 2001-12-11 2003-06-25 镇水清 Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method
CN106581599A (en) * 2015-10-15 2017-04-26 贵州瑞和制药有限公司龙里药厂 Drug for treating rheumatism and preparation method thereof
CN108619478A (en) * 2018-07-13 2018-10-09 魏明辉 A kind of Chinese medicine preparation for treating treating rheumatic ostealgia
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