CN105213759A - A kind of Chinese medicine composition and preparation method and its usage for the treatment of folliculitis - Google Patents
A kind of Chinese medicine composition and preparation method and its usage for the treatment of folliculitis Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of Chinese medicine composition for the treatment of folliculitis, with Medulla Tetrapanacis, Radix Angelicae Sinensis, Herba Schizonepetae, Rhizoma Chuanxiong, Herba Leonuri, Herba Plantaginis, Arisaema Cum Bile, the Fructus Kochiae, Flos Hibisci, Bulbus Lilii, Radix Achyranthis Bidentatae is crude drug composition.The invention still further relates to a kind of preparation method and its usage for the treatment of the Chinese medicine composition of folliculitis.Chinese medicine composition of the present invention has the antipruritic effect of eliminating dampness and expelling toxin, benefiting qi and nourishing blood, clearing heat for detumescence, has therapeutical effect through clinical verification to folliculitis.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of folliculitis and its production and use.
Background technology
Folliculitis is that pyococcus is invaded around follicular orifice, is confined to the inflammation on hair follicle top, is divided into suppurative with apyetous two kinds, is more common in immunocompromised person or diabetics, is apt to occur in head, napex, face.Folliculitis, from the beginning of being red lex primaria pimple, develops into papular abscess rapidly later, then dry, incrustation, conscious pruritus or mild pain.Motherland's medical science is early on the books to primary disease.
For folliculitis, modern medicine often applies external preparation anti-inflammation formulation treatment for oral administration as iodine tincture combines, and as antibiotic, local available 1% neomycin ointment, mupirocin ointment, fusidic acid ointment or 2% iodine tincture are coated with outward, also can try out ultraviolet radiation.Market also exists the Chinese medicine formula of a lot for the treatment of folliculitis, but mostly effect is bad, and expensive.Therefore the medicine recovered for folliculitis must safety, effective, have no side effect.Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect is strong, instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of Chinese medicine preparation to recover for folliculitis, for folliculitis, there is very important clinical meaning.
Summary of the invention
Therefore, the technical problem to be solved in the present invention is to overcome in prior art treats the defect that folliculitis effect of drugs is poor, side effect is many, thus provides a kind of Chinese medicine composition for the treatment of folliculitis.
The present invention proposes following technical scheme to solve the problem, a kind of Chinese medicine composition for the treatment of folliculitis, the weight portion of the crude drug of this Chinese medicine is: Medulla Tetrapanacis 3-11 part, Radix Angelicae Sinensis 5-20 part, Herba Schizonepetae 3-12 part, Rhizoma Chuanxiong 6-15 part, Herba Leonuri 5-20 part, Herba Plantaginis 4-15 part, Arisaema Cum Bile 5-15 part, Fructus Kochiae 2-10 part, Flos Hibisci 5-20 part, Bulbus Lilii 10-20 part, Radix Achyranthis Bidentatae 5-20 part.
The weight portion of above-mentioned raw material of Chinese medicine medicine is preferably: Medulla Tetrapanacis 5-9 part, Radix Angelicae Sinensis 8-15 part, Herba Schizonepetae 5-10 part, Rhizoma Chuanxiong 8-12 part, Herba Leonuri 8-15 part, Herba Plantaginis 6-9 part, Arisaema Cum Bile 8-10 part, Fructus Kochiae 5-8 part, Flos Hibisci 8-18 part, Bulbus Lilii 14-16 part, Radix Achyranthis Bidentatae 8-15 part.
The weight portion of above-mentioned raw material of Chinese medicine medicine is preferably: Medulla Tetrapanacis 9 parts, Radix Angelicae Sinensis 15 parts, Herba Schizonepetae 10 parts, Rhizoma Chuanxiong 12 parts, Herba Leonuri 15 parts, Herba Plantaginis 9 parts, Arisaema Cum Bile 10 parts, the Fructus Kochiae 6 parts, Flos Hibisci 18 parts, Bulbus Lilii 14 parts, Radix Achyranthis Bidentatae 15 parts.
The weight portion of above-mentioned raw material of Chinese medicine medicine is preferably: Medulla Tetrapanacis 6 parts, Radix Angelicae Sinensis 9 parts, Herba Schizonepetae 6 parts, Rhizoma Chuanxiong 10 parts, Herba Leonuri 8 parts, Herba Plantaginis 6 parts, Arisaema Cum Bile 10 parts, the Fructus Kochiae 8 parts, Flos Hibisci 8 parts, Bulbus Lilii 14 parts, Radix Achyranthis Bidentatae 8 parts.
The weight portion of above-mentioned raw material of Chinese medicine medicine is preferably: containing Medulla Tetrapanacis 5 parts, Radix Angelicae Sinensis 8 parts, Herba Schizonepetae 5 parts, Rhizoma Chuanxiong 8 parts, Herba Leonuri 10 parts, Herba Plantaginis 7 parts, Arisaema Cum Bile 8 parts, the Fructus Kochiae 5 parts, Flos Hibisci 10 parts, Bulbus Lilii 15 parts, Radix Achyranthis Bidentatae 10 parts.
Present invention also offers a kind of Chinese medicine preparation for the treatment of folliculitis, described Chinese medicine composition is prepared into the conventional pharmaceutical dosage forms such as tablet, capsule, granule, soft capsule, powder, solution, water preparation, powder or honeyed pill.
Present invention also offers the preparation method of described Chinese medicine preparation, the dosage form of described Chinese medicine preparation is preferably granule or capsule, described preparation method is for take all raw medicinal materials according to ratio of weight and number, decoct with water 2-3 time, each 10-20 times water gaging, soak, decoct 20-30 minute, filter, merging filtrate, is concentrated into extractum by the filtrate evaporated under reduced pressure of merging; After adding adjuvant, mixing is sieved, and prepares granule or capsule.
Present invention also offers the purposes of a kind of described Chinese medicine composition in preparation treatment folliculitis medicine.
In the present invention, the pharmacological property of each raw material is as follows:
Medulla Tetrapanacis: attach to the lung and stomach meridians, clear snobbish water; Lactogenesis, for the puckery pain of stranguria; Dysuria; Edema; Jaundice; Damp-warm diseases; Oliguria with reddish urine; Puerperal, breast was few; Amenorrhea; Leukorrhagia.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea is suffered from abdominal pain, and lump in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down.
Herba Schizonepetae: acrid in the mouth, slightly warm in nature; Return lung, Liver Channel.Induce sweat, loose wind, rash.For flu, headache, measles, rubella, skin infection from the beginning of, have blood in stool, metrorrhagia, puerperal blood faints.
Rhizoma Chuanxiong: pungent, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Herba Leonuri: acrid in the mouth is bitter, cool, invigorates blood circulation, silts of dispelling, regulating menstruation, disappears water, treatment menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.
Herba Plantaginis: sweet in the mouth, cold in nature.Return liver, kidney, urinary bladder channel.Heat clearing away, diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Arisaema Cum Bile: bitter in the mouth, cool in nature.Enter the heart, liver, lung three warp.Clearing away fire and eliminating phlegm, relieving convulsion fixed chronic.Control middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.
The Fructus Kochiae: clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
Flos Hibisci: sweet in the mouth, hardship, cool in nature; Return spleen, lung, Liver Channel.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Rush down blood for hemorrhoidal hamorrhage, red white dysentery, bleeding hemorrhoids, cough due to lung-heat, hemoptysis leucorrhea, furuncle carbuncle, scald.
Bulbus Lilii: sweet in the mouth, cold in nature.GUIXIN, lung meridian.Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.
Radix Achyranthis Bidentatae: function cures mainly: relieve internal heat anticancer; Blood circulation promoting and blood stasis dispelling; By silt eliminating impediment; Antiinflammatory diuresis; Purify the blood sterilization; Loose blood and relieving pain.
Technical solution of the present invention, tool has the following advantages:
The present invention selects natural plants, biological Chinese medicine to be raw material, adopts the comprehensive function of each taste Chinese medicine to treat folliculitis, without any side effects, and can not cause damage to health.
The present invention adopts Medulla Tetrapanacis, Radix Angelicae Sinensis, Herba Schizonepetae, Rhizoma Chuanxiong, Herba Leonuri, Herba Plantaginis, Arisaema Cum Bile, the Fructus Kochiae, Flos Hibisci, Bulbus Lilii, the multiple medical material scientific combination of Radix Achyranthis Bidentatae, each medicine supplements and complements each other, play heat-clearing and toxic substances removing, detumescence and apocenosis altogether, rash of inducing sweat, effect of eliminating dampness and expelling toxin, benefiting qi and nourishing blood, clearing heat for detumescence, itch-stopping bactericidal, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs targeting is comparatively strong, and drug effect is gone directly focus.The present invention is through clinical practice for many years, and be used for the treatment of folliculitis instant effect, short treating period, have determined curative effect, have no side effect, cost is low, the feature that cure rate is high.Total effective rate is 98%, has no side effect, and not easily recurs after curing, and is with a wide range of applications.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine composition for the treatment of folliculitis, containing Medulla Tetrapanacis 9g, Radix Angelicae Sinensis 15g, Herba Schizonepetae 10g, Rhizoma Chuanxiong 12g, Herba Leonuri 15g, Herba Plantaginis 9g, Arisaema Cum Bile 10g, Fructus Kochiae 6g, Flos Hibisci 18g, Bulbus Lilii 14g, Radix Achyranthis Bidentatae 15g.
Preparation method, for take all raw medicinal materials according to ratio of weight and number, decocts with water 3 times, for the first time 12-14 times of water gaging, soak, decoct, filter, second time adds 8-10 times of water gaging, decocts, and filters, third time adds 8-10 times of water gaging, decoct, filter, discarded medicinal residues, merge three filtrates, the filtrate evaporated under reduced pressure of merging is concentrated into extractum; After adding adjuvant, mixing is sieved, and prepares granule.
Embodiment 2: a kind of Chinese medicine composition for the treatment of folliculitis, containing Medulla Tetrapanacis 6g, Radix Angelicae Sinensis 9g, Herba Schizonepetae 6g, Rhizoma Chuanxiong 10g, Herba Leonuri 8g, Herba Plantaginis 6g, Arisaema Cum Bile 10g, Fructus Kochiae 8g, Flos Hibisci 8g, Bulbus Lilii 14g, Radix Achyranthis Bidentatae 8g.
Take all raw medicinal materials according to ratio of weight and number, decoct with water 2 times, for the first time 12-14 times of water gaging, soak, decoct, filter, second time adds 8-10 times of water gaging, and decoction filters, and discarded medicinal residues, merge three filtrates, the filtrate evaporated under reduced pressure of merging is concentrated into extractum; After adding adjuvant, mixing is sieved, and prepares capsule.
Embodiment 3: a kind of Chinese medicine composition for the treatment of folliculitis, containing Medulla Tetrapanacis 5g, Radix Angelicae Sinensis 8g, Herba Schizonepetae 5g, Rhizoma Chuanxiong 8g, Herba Leonuri 10g, Herba Plantaginis 7g, Arisaema Cum Bile 8g, Fructus Kochiae 5g, Flos Hibisci 10g, Bulbus Lilii 15g, Radix Achyranthis Bidentatae 10g.
In above-described embodiment, what provide is granules medicine, and as the embodiment that can convert, this medicine by using conventional preparation method, can be prepared into electuary, tablet, capsule, the watered pill, honeyed pill, water preparation.
For evaluating the impact of Chinese medicine composition of the present invention on folliculitis, following experimental example grouping is:
Matched group, administration group be 40 people respectively, and M-F is within the scope of 1:0.8-1.2
Case inclusion criteria: consistent red lex primaria pimple or pityriasis rubra impetigo appear in the follicular orifice of scalp, upper breast, back, buttocks, and surrounding blush has inflammation, have no wire hypha body and oval spore in heaps under light microscopic.
Excluded cases standard: in 0.5 month, once system uses antibiotic or patient to suffer from the patient of hepatorenal disease; Be in the women of trimester of pregnancy or age of sucking or compliance is poor can not the patient of regularly further consultation.
Therapeutic Method:
Treatment group takes the granule that the present invention obtains according to specific embodiment 1, and every bu sooner or later twice mixing in water for oral taking is used.
Matched group externally used compound Chloramphenicol Tincture, uses to specifications.
In two groups, per course for the treatment of is 2 weeks, and treatments period rule of life, does not stay up late; Avoid pungent food, thing that greasy and raw meat is sent out; Avoid tobacco and wine, and regulate feelings will, keep being emotionally stable.
Criterion of therapeutical effect
Recovery from illness: erythra disappears completely, clinical symptom disappearance;
Effective: deflorescence more than 70%, clinical symptoms obviously alleviates;
Take a turn for the better: skin is examined and disappeared 40% ~ 70%, clinical symptom relief;
Invalid: skin examines the < 40% that disappears, clinical symptoms is without improvement or increase the weight of.
Result
Through the treatment of 2 weeks, treatment group was fully recovered 25 people, effective 8 people, and take a turn for the better 5 people, invalid 2 people, and total effective rate is 98%; Matched group cures 13 people, effective 7 people, and take a turn for the better 10 people, invalid 10 people, and total effective rate is 75%.Two groups of comparitive study, treatment group total effective rate is significantly higher than matched group.
Visible, the medicine that the present invention obtains can safe and effective treatment folliculitis, has good medical science promotional value.
In sum, Chinese medicine composition of the present invention has good therapeutic effect for folliculitis, and total effective rate is 98%, and not easily recurs after curing, and has no side effect, is with a wide range of applications.
Concrete case:
1, Lee, man, 16 years old, Shanghai people.Patient suffers from folliculitis, and continuous several weeks, heavy time light during symptom, repeatedly do not heal, the degree of pruritus did not differ yet, sometimes with hypodynia.Once used various medicine, effect is all not good.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom is obviously alleviated, and continues to take 2 courses for the treatment of, and symptom all disappears.Follow up a case by regular visits to and do not recur so far.
2, Wang so-and-so, female, 23 years old, student, many places follicular infection, local was red and swollen, heat, bitterly.From taking erythromycin etc., local iodine tincture embrocates affected part treatment two weeks, poor effect.Cure after taking 2 courses for the treatment of of Chinese medicine composition of the present invention, follow up a case by regular visits to after half a year, do not recur.
3, king so-and-so, female, 48 years old, peasant, suffered from folliculitis, from the beginning of being cystic impetigo, after become papular pustule, repeatedly do not heal, the degree of pruritus also differs, sometimes with hypodynia.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after then taking 3 courses for the treatment of, physical recovery is normal, above transference cure.Follow up a case by regular visits to and do not recur so far.
Obviously, above-described embodiment is only for clearly example being described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of extending out or variation be still among the protection domain of the invention.
Claims (8)
1. treat a Chinese medicine composition for folliculitis, it is characterized in that, comprise the crude drug of following weight portion: Medulla Tetrapanacis 3-11 part, Radix Angelicae Sinensis 5-20 part, Herba Schizonepetae 3-12 part, Rhizoma Chuanxiong 6-15 part, Herba Leonuri 5-20 part, Herba Plantaginis 4-15 part, Arisaema Cum Bile 5-15 part, Fructus Kochiae 2-10 part, Flos Hibisci 5-20 part, Bulbus Lilii 10-20 part, Radix Achyranthis Bidentatae 5-20 part.
2. the Chinese medicine composition for the treatment of folliculitis according to claim 1, is characterized in that, comprises Medulla Tetrapanacis 5-9 part, Radix Angelicae Sinensis 8-15 part, Herba Schizonepetae 5-10 part, Rhizoma Chuanxiong 8-12 part, Herba Leonuri 8-15 part, Herba Plantaginis 6-9 part, Arisaema Cum Bile 8-10 part, Fructus Kochiae 5-8 part, Flos Hibisci 8-18 part, Bulbus Lilii 14-16 part, Radix Achyranthis Bidentatae 8-15 part.
3. the Chinese medicine composition for the treatment of folliculitis according to claim 2, is characterized in that, comprises Medulla Tetrapanacis 9 parts, Radix Angelicae Sinensis 15 parts, Herba Schizonepetae 10 parts, Rhizoma Chuanxiong 12 parts, Herba Leonuri 15 parts, Herba Plantaginis 9 parts, Arisaema Cum Bile 10 parts, the Fructus Kochiae 6 parts, Flos Hibisci 18 parts, Bulbus Lilii 14 parts, Radix Achyranthis Bidentatae 15 parts.
4. the Chinese medicine composition for the treatment of folliculitis according to claim 2, is characterized in that, comprises Medulla Tetrapanacis 6 parts, Radix Angelicae Sinensis 9 parts, Herba Schizonepetae 6 parts, Rhizoma Chuanxiong 10 parts, Herba Leonuri 8 parts, Herba Plantaginis 6 parts, Arisaema Cum Bile 10 parts, the Fructus Kochiae 8 parts, Flos Hibisci 8 parts, Bulbus Lilii 14 parts, Radix Achyranthis Bidentatae 8 parts.
5. the Chinese medicine composition for the treatment of folliculitis according to claim 2, is characterized in that, comprises Medulla Tetrapanacis 5 parts, Radix Angelicae Sinensis 8 parts, Herba Schizonepetae 5 parts, Rhizoma Chuanxiong 8 parts, Herba Leonuri 10 parts, Herba Plantaginis 7 parts, Arisaema Cum Bile 8 parts, the Fructus Kochiae 5 parts, Flos Hibisci 10 parts, Bulbus Lilii 15 parts, Radix Achyranthis Bidentatae 10 parts.
6. treat a Chinese medicine preparation for folliculitis, it is characterized in that, by Chinese medicine composition described in any one of claim 1-5, be prepared into the conventional formulations such as tablet, capsule, granule, soft capsule, powder, solution, water preparation, powder or honeyed pill.
7. the preparation method of Chinese medicine preparation according to claim 6, it is characterized in that, the dosage form of described Chinese medicine preparation is preferably granule, and described preparation method, for take all raw medicinal materials according to ratio of weight and number, decocts with water 2-3 time, each 10-20 times water gaging, soak, decoct 20-30 minute, filter, merging filtrate, is concentrated into extractum by the filtrate evaporated under reduced pressure of merging; After adding adjuvant, mixing is sieved, and prepares granule.
8. the purposes of the Chinese medicine composition according to any one of claim 1-5 in preparation treatment folliculitis medicine.
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