CN111617172A - A topical Chinese medicinal composition and its preparation method - Google Patents
A topical Chinese medicinal composition and its preparation method Download PDFInfo
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- CN111617172A CN111617172A CN202010443337.5A CN202010443337A CN111617172A CN 111617172 A CN111617172 A CN 111617172A CN 202010443337 A CN202010443337 A CN 202010443337A CN 111617172 A CN111617172 A CN 111617172A
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Classifications
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Abstract
The invention discloses an external traditional Chinese medicine composition, and the raw material medicines of the external traditional Chinese medicine composition comprise frankincense, myrrh, radix interrupters, rhizoma drynariae, rhizoma smilacis glabrae powder, pseudo-ginseng, sappan wood, mint, dragon's blood, suberect spatholobus stem and catechu. The invention can reduce the swelling within 24 hours for traumatic injury and within 3 days for fracture, has obvious pain relieving effect, gradually removes stasis and quickly heals; the femoral head necrosis can promote the nutrition and growth of bones and cartilages, is convenient to use, causes no pain to patients, and can be recovered in a relatively short period even for severe patients.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, and in particular relates to an external traditional Chinese medicine composition and a preparation method thereof.
Background
Non-open trauma, also called closed trauma, refers to the condition of the trauma where there is no skin damage or the connection between the subcutaneous tissue, blood vessel, nerve, muscle, and bone, and the external environment. Which corresponds to open trauma. The non-open trauma mainly includes closed trauma caused by traumatic injury, closed fracture caused by accumulated strain, or closed fracture caused by disease.
Traumatic injury refers to injuries caused by traumatic injuries, bruising, sports injuries and the like, and the injuries mainly include pain, swelling and pain, extravasated blood, fracture, dislocation and the like, mainly soft tissue injuries, and extravasated blood swelling and pain, disharmony between qi and blood and blockage of channels and collaterals at affected parts.
Fracture refers to the continuous complete or partial fracture of bone structure, including the fracture caused by direct or indirect violence or the fracture caused by accumulated strain, and other diseases, such as osteoporosis, osteomyelitis, etc., can also cause the fracture.
Femoral head necrosis is a pathological evolution process, which initially occurs in a weight bearing area of a femoral head, and a necrotic bone trabecular structure is damaged under stress, namely, a microfracture and a subsequent repair process aiming at damaged bone tissues. The cause of osteonecrosis is not eliminated, the repair is incomplete, and the process of injury-repair is continued, which results in the structural change of femoral head, the collapse and deformation of femoral head, the arthritis and the dysfunction. There are two causes of femoral head necrosis: the healing of the fracture and poor reduction of the femoral tibia fracture occurs, the load bearing stress of the load bearing trabecula in the femoral head is reduced, the stress injury occurs, and the necrosis occurs after the fracture healing and the load bearing walking of a patient; the other is the bone tissue itself, such as chronic alcoholism or osteonecrosis induced by glucocorticoid use.
Traditional Chinese medicine has irreplaceable advantages in treating the injuries and the diseases. However, the traditional traumatic injury medicines (such as spray) and the conventional fracture treatment methods have long healing process, slow recovery speed and poor effect. However, the current medical treatment method for femoral head necrosis is complex and expensive, and even the hip joint needs to be replaced for serious patients. Therefore, an effective Chinese medicinal composition is needed to solve the above problems.
Disclosure of Invention
In one aspect of the invention, aiming at the defect of poor treatment effect of the medicines and methods for treating non-open trauma or femoral head necrosis in the prior art, the invention provides an external traditional Chinese medicine composition and a preparation method thereof.
The technical scheme provided by the invention is as follows:
a topical Chinese medicinal composition comprises Olibanum, Myrrha, radix Dipsaci, rhizoma Drynariae, rhizoma Smilacis Bockii, Notoginseng radix, lignum sappan, herba Menthae, sanguis Draxonis, caulis Spatholobi and Catechu.
The invention creates a compound medicine with multiple efficacies, the same efficacy parts are superposed to strengthen the efficacy, and different efficacy parts are mutually assisted, thereby finally achieving the effects of taking effect quickly and treating both principal and secondary aspects of diseases. For example, frankincense and myrrh are used for relieving swelling, pseudo-ginseng, dragon's blood and safflower are used for dissipating blood stasis and activating blood circulation, rhizoma cibotii, rhizoma smilacis glabrae and mint are added for removing dampness and expelling wind, and borneol and catechu are used for helping convergence and regeneration of tissue, so that the efficacies supplement each other and interact with each other.
Preferably, in an embodiment of the present invention, the raw material drugs of the external traditional Chinese medicine composition comprise 3 to 5 parts by weight of frankincense, 3 to 5 parts by weight of myrrh, 5 to 7 parts by weight of discontinuous drugs, 5 to 7 parts by weight of rhizoma drynariae, 2 to 4 parts by weight of rhizoma smilacis glabrae, 3 to 5 parts by weight of pseudo-ginseng, 3 to 5 parts by weight of sappan wood, 3 to 5 parts by weight of mint, 1 to 3 parts by weight of dragon's blood, 5 to 7 parts by weight of caulis spatholobi and 2 to 4 parts by weight of catechu.
More preferably, in an embodiment of the present invention, the raw material drugs of the external traditional Chinese medicine composition further include 5 to 7 parts by weight of rhizoma cibotii, 3 to 5 parts by weight of radix angelicae, 1 to 3 parts by weight of safflower and 1 to 2 parts by weight of borneol.
Preferably, in one embodiment of the present invention, the raw material drugs of the external traditional Chinese medicine composition comprise the following components in parts by weight: 3-5 parts of frankincense, 3-5 parts of myrrh, 5-7 parts of discontinuous drugs, 5-7 parts of rhizoma drynariae, 2-4 parts of buddha's warrior attendant powder, 3-5 parts of pseudo-ginseng, 3-5 parts of sappan wood, 3-5 parts of mint, 1-3 parts of dragon's blood, 5-7 parts of caulis spatholobi, 2-4 parts of catechu, 5-7 parts of rhizoma cibotii, 3-5 parts of radix angelicae, 1-3 parts of safflower and 1-2 parts of borneol.
More preferably, in one embodiment of the present invention, the raw material drugs of the external traditional Chinese medicine composition comprise the following components in parts by weight: 4 parts of frankincense by weight, 4 parts of myrrh by weight, 6 parts of radix aconiti lateralis preparata by weight, 6 parts of rhizoma drynariae by weight, 3 parts of rhizoma smilacis glabrae by weight, 4 parts of pseudo-ginseng by weight, 4 parts of sappan wood by weight, 4 parts of mint by weight, 2 parts of dragon blood by weight, 6 parts of caulis spatholobi by weight, 3 parts of catechu by weight, 6 parts of rhizoma cibotii by weight, 4 parts of radix angelicae by weight, 2 parts of safflower by weight and 1 part of borneol by weight.
In the external traditional Chinese medicine composition, the monarch drugs are frankincense, myrrh, teasel root, rhizoma cibotii, rhizoma drynariae and rhizoma smilacis glabrae powder. Wherein,
boswellia carterii Birdw of Boswellia carterii of Burseraceae and Boswellia bhahahurdajiana Birdw of the same genus. Pungent, bitter and warm in nature. It enters heart, liver and spleen meridians. Has effects of promoting blood circulation, activating qi-flowing, relieving pain, eliminating swelling and promoting granulation. The compendium of materia Medica records: ' Xiao Feng Qu Du, Tu Li Hu Xin, Hu Huo Ding Tong, treat dystocia and fracture of women. "Ru Xiang flees and enters heart meridian to activate blood and relieve pain, so it is the key herb for abscess, deep-rooted carbuncle, sores and ulcers, and cardialgia and abdominal pain. … … it is used in obstetrical department and also used in the successful blood-activating ear. "
Myrrha is dried resin of Commiphora myrrha Engl. or Commiphoramolmol Engl. of Burseraceae. Pungent and bitter in flavor and mild in nature. It enters heart, liver and spleen meridians. Has effects in removing blood stasis, relieving pain, eliminating swelling, and promoting granulation. It is often used for treating thoracic obstruction, heart pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum stasis, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, sore and ulcer.
Teasel root, also known as "monk's head", is the dry root of Dipsacus asper wall, exhenry, a perennial herb of the family teasel, and is named because it can "continue to fracture and join bones". The Yunnan herbal medicine records: nourishing liver, strengthening tendons and bones, fixing meridians, relieving soreness of meridians and bones, preventing miscarriage, treating leucorrhea, promoting hematopoiesis, removing blood stasis, arresting abortion, relieving cough and hemoptysis, and treating red, white and turbid urine. Has the functions of nourishing liver and kidney, reuniting bones and muscles and regulating blood vessels.
Rhizoma Cibotii is dried rhizome of Cibotium barometz (L.) J.Sm. of Unionidae. Bitter and sweet in taste and warm in nature. It enters liver and kidney meridians. Has effects of dispelling pathogenic wind and removing dampness, nourishing liver and kidney, and strengthening waist and knee.
Rhizoma Drynariae is a plant of the family Drynariaceae, genus Drynariae, belonging to the genus Epighurium. The rhizoma drynariae rhizome used as the medicine is rich in effective components such as flavone, alkaloid, phenols and the like, and has the effects of removing blood stasis, relieving pain, reuniting bones and tendons, treating toothache, low back pain, chronic diarrhea and the like.
Jingang san, named as the traditional Chinese medicine prescription. From the book II of Qing Bao Lixiao secret prescriptions. Has the effects of dispelling wind and eliminating dampness, reducing swelling and healing sore, removing blood stasis and healing wound. It is used for treating toxic swelling, scrofula and furunculosis.
In the present invention, the Jingangsan can be prepared according to the formula in volume two of the "Qing Bao Lixiao secret prescription", or any commercially available product can be purchased. Preferably, in one embodiment of the present invention, the diamond dust is composed of the following raw material drugs: 3 parts of semen cassiae, 3 parts of catechu, 2 parts of yellow lead, 2 parts of kangqing, 2 parts of venenum bufonis, 2 parts of calomel, 1 part of dried alum, 0.2 part of Moschus and 0.2 part of borneol.
In the external traditional Chinese medicine composition, ministerial drugs are pseudo-ginseng, catechu, suberect spatholobus stem, sappan wood and dragon's blood.
Wherein,
pseudo-ginseng, a perennial upright herb of Panax of Araliaceae, is warm in nature and pungent in taste, has remarkable effects of promoting blood circulation, removing blood stasis, relieving swelling and alleviating pain by using the root of the plant as a medicine, and has the reputation of 'Jinbuzhang' and 'Nanguo Shencao'. Because it is usually a plant of the genus Panax and its active substances are higher and more than that of Panax, it is also called "king of Ginseng" by modern Chinese materia medica pharmacologist. The Qing dynasty pharmaceutical book 'Ben Cao gang mu Shi Yi' records: ginseng, radix Ginseng and Notoginseng are the most precious of the Chinese herbs, because it tonifies qi the first, and it tonifies blood the first, and its flavor is the same and the same. It is used to treat hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracico-abdominal pain, and traumatic injury with swelling and pain.
Catechu is dried soft extract of peeled branch and dried stem of Acacia catechu (L.f.) of Leguminosae. Has the effects of promoting blood circulation, relieving pain, stopping bleeding, promoting granulation, astringing dampness, promoting wound healing, clearing lung-heat and eliminating phlegm. Can be used for treating traumatic injury, traumatic hemorrhage, hematemesis, epistaxis, unhealing pyocutaneous disease, eczema, and cough due to lung heat.
Caulis spatholobi, perennial liana, is a traditional Chinese medicine for promoting blood circulation and enriching blood, and is wild in mountain valley forests and mountain shrubs. Researches show that the caulis Spatholobi extract, total flavone and chemical components contained in the caulis Spatholobi extract have various pharmacological activities including influence on blood circulation system, anti-tumor, antivirus, antioxidation, etc. The stem used as a medicine is one of the main sources of the traditional Chinese medicine caulis spatholobi and has the efficacies of dispelling wind and activating blood circulation, relaxing tendons and activating collaterals. It can be used for treating soreness of waist and knees, numbness, paralysis, and menoxenia.
Sappan wood, the dried heartwood of Caesalpinia sappan L. Has effects of promoting blood circulation, removing blood stasis, relieving swelling and pain. Can be used for treating traumatic injury, fracture, injury of tendons, blood stasis, swelling and pain, amenorrhea, dysmenorrhea, puerperal stagnation, thoracic and abdominal pain, carbuncle, cellulitis, and swelling and pain.
Sanguis Draxonis is prepared from resin exuded from fruit of daemonorops draco of Palmaceae. Sweet, salty and neutral in nature. It enters heart and liver meridians. Has effects of promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, promoting granulation, and healing sore. Can be used for treating traumatic injury, heart and abdomen blood stasis and pain, traumatic hemorrhage, and unhealed skin and external diseases.
In the external traditional Chinese medicine composition, the adjuvant drugs are angelica dahurica, mint and safflower. Wherein,
the angelica dahurica is a big and old herb, and has the functions of dispelling diseases, removing dampness, expelling pus, promoting granulation, promoting blood circulation, relieving pain and the like by using the root as a medicine. Can be used for treating wind-cold type common cold, headache, rhinitis, and toothache. It can also be used as perfume for treating leucorrhea with red and white discharge, pain, furuncle, and toxic swelling. The compendium of materia Medica records: radix angelicae is white and pungent in flavor, and can play a role in improving hand yangming; warmth in nature and thick qi, sufficient yang-yin to clear up; fragrant, ascending and entering the lung meridian of Taiyin. Wind-heat in the three meridians, such as head, eye, eyebrow and tooth; for example, the damp-heat in the three meridians can also cause diseases such as fistula, leukorrhagia, and superficial infection; wind-heat is pungent in property and damp-heat is warm in nature. It is a main herb of yangming, so it can also be used for treating blood disease, fetal disease, promoting pus discharge, promoting granulation and relieving pain. Treating nasosinusitis, toothache, hematuria, glabellar pain, constipation of large intestine, blood wind syndrome of women, regurgitation, and vomiting of food; relieve arsenic toxicity, snake bite, epistaxis, incised wound and incised wound. "
Mint, also known as "Yindancao" is a plant of Labiatae, and is a sweating and antipyretic for treating influenza, headache, conjunctival congestion, fever, sore throat, and swollen gum. Can be used for treating wind-heat common cold, headache, sore throat, food stagnation, flatulence, aphtha, toothache, scabies, urticaria, early stage of epidemic febrile disease, rubella pruritus, stagnation of qi due to depression of the liver, chest distress, and hypochondriac pain. The compendium of materia Medica records: mint, pungent in flavor and cool in flavor can disperse and clear and is used for dispelling wind and dissipating heat. So it is the key herb for headache, wind syndrome of head, eye, throat and mouth, infantile convulsions, scrofula, sores and scabies. "
Carthami flos, which is dried flower of Carthamus tinctorius L. Has the functions of promoting blood circulation to restore menstrual flow, eliminating blood stasis and relieving pain. Can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain.
In the external traditional Chinese medicine composition, the messenger medicine is borneol, also called borneol, orange slice, blumea, borneol, tomatillo, plum blossom, borneol, plum blossom ice and the like, and is prepared by distilling stems and leaves of blumea balsamifera of Compositae or branches and leaves of camphor of Lauraceae plant. Also can be obtained by a series of chemical processes using turpentine. It can be used for treating block pattern of coma, conjunctival congestion with swelling and pain, pharyngitis, aphtha, sore and ulcer with swelling and pain, and unhealed ulcer. The records in Ben Cao Jing Shu (herbal Jing Shu): it is contraindicated for patients with apoplexy due to qi and blood deficiency, but without exogenous pathogenic wind; the infantile vomiting and diarrhea with convulsion is slow spleen wind, the acute convulsion is due to excess heat, and the slow convulsion is due to deficiency-cold; herbs should not be used for dim eyes due to deficiency of liver and kidney. "
In the external traditional Chinese medicine composition, the safflower, the borneol, the cibotium rhizome and the angelica dahurica are used as auxiliary medicines, so that the treatment effect of the main medicine can be enhanced.
In another aspect of the invention, a traditional Chinese medicine external application agent is provided, and the traditional Chinese medicine external application agent comprises the external traditional Chinese medicine composition.
The traditional Chinese medicine is widely applied in traditional Chinese medicine surgery, and can directly act on local parts, so that the effect is good, and the medicine is convenient to use. The main form of the Chinese medicinal external application agent comprises ointment or powder.
The ointment may comprise, for example, ointment, which is prepared by adding appropriate matrix into medicine, and making into easily-coated external preparation by mixing, grinding, decocting, etc., and may comprise vegetable oil ointment, adeps Ambrosus ointment, adeps Caprae Seu Ovis ointment, Mel ointment, oil ointment, marrow ointment, vinegar ointment, milk ointment, wax ointment, egg white ointment, etc., or composite matrix ointment prepared from multiple matrixes, such as oil wax ointment; a soft plaster is an external preparation prepared by adding the medicine into a proper matrix or preparing into an ointment by a proper method, and spreading the ointment on a backing material, and is generally used immediately; plaster, including black plaster, white plaster and other plasters, such as rosin plaster, sweetgum plaster, and adhesive plaster. In one embodiment of the invention, the paste is a rosin paste.
Preferably, the preparation method of the paste comprises the following steps: soaking the raw material medicines of the external traditional Chinese medicine composition in 200-250 parts by weight of sesame oil for 24 hours, filtering the oil, filtering out dregs, adding 80-120 parts by weight of rosin, decocting the obtained sesame oil to obtain condensed oil, and naturally cooling to obtain the ointment.
The ointment of the present invention may further comprise any suitable pharmaceutically acceptable excipients, carriers, such as viscosity-increasing agents, adhesion-inducing agents, which are all considered to be included in the protection scope of the present invention.
The Chinese medicine external application agent can also be prepared into powder. The raw materials of the external traditional Chinese medicine composition can be prepared into powder by any suitable method through crushing and uniformly mixing. Powders for external use are typically sieved through a 120 mesh sieve.
The powder of the present invention may further comprise any suitable pharmaceutically acceptable excipients, carriers, such as viscosity increasing agents, viscosity inducing agents, which are all considered to be included in the scope of the present invention.
The powder of the invention is applied to the affected part after being blended with honey or warm water and the like.
In another aspect of the invention, the invention provides the use of the above topical Chinese medicinal composition or the above topical Chinese medicinal preparation in the preparation of a medicament for treating non-open trauma or femoral head necrosis.
Preferably, the non-open trauma is closed trauma caused by traumatic injury, closed fracture caused by accumulated strain, or closed fracture caused by disease.
The invention has the beneficial effects that:
the invention uses the traditional Chinese medicine to prepare plaster or powder for external application, can be conveniently used for treating traumatic injury, fracture and femoral head necrosis, and has simple use method, obvious recovery effect and low treatment cost.
The invention can reduce the swelling within 24 hours for traumatic injury and within 3 days for fracture, has obvious pain relieving effect, gradually removes stasis and quickly heals; the femoral head necrosis can promote the nutrition and growth of bones and cartilages, is convenient to use, causes no pain to patients, and can be recovered in a relatively short period even for severe patients.
Detailed Description
The invention discloses an external traditional Chinese medicine composition and a preparation method thereof, and a person skilled in the art can realize the external traditional Chinese medicine composition by properly improving process parameters by referring to the content. It is expressly intended that all such alterations and modifications which are obvious to those skilled in the art are deemed to be incorporated herein by reference, and that the techniques of the invention may be practiced and applied by those skilled in the art without departing from the spirit, scope and range of equivalents of the invention.
In the present invention, unless otherwise specified, scientific and technical terms used herein have the meanings that are commonly understood by those skilled in the art.
In order to make those skilled in the art better understand the technical solution of the present invention, the following detailed description of the present invention is provided with reference to specific embodiments.
Example 1:
the raw material medicines of the external traditional Chinese medicine composition comprise the following components: 40g of frankincense, 40g of myrrh, 60g of radix aconiti lateralis preparata, 60g of rhizoma drynariae, 30g of rhizoma smilacis glabrae powder, 40g of pseudo-ginseng, 40g of sappan wood, 40g of mint, 20g of dragon's blood, 60g of suberect spatholobus stem and 30g of catechu.
Soaking the medicines in 2400g of sesame oil for 24 hours, enabling the medicine effect to permeate into the sesame oil, filtering the oil, filtering out medicine residues, decocting the sesame oil containing the medicine components into condensed oil, adding 1000g of rosin in due time, naturally cooling the plaster after the plaster is decocted, and spreading and packaging the decocted plaster by adopting a modern process after the plaster is placed for 3 days to form a product.
Example 2:
the raw material medicines of the external traditional Chinese medicine composition comprise the following components: 40g of frankincense, 40g of myrrh, 60g of radix aconiti lateralis preparata, 60g of rhizoma drynariae, 30g of rhizoma smilacis glabrae powder, 40g of pseudo-ginseng, 40g of sappan wood, 40g of mint, 20g of dragon's blood, 60g of caulis spatholobi, 30g of catechu, 20g of safflower, 10g of borneol, 60g of rhizoma cibotii and 40g of angelica dahurica.
Soaking the medicines in 2400g of sesame oil for 24 hours, enabling the medicine effect to permeate into the sesame oil, filtering the oil, filtering out medicine residues, decocting the sesame oil containing the medicine components into condensed oil, adding 1000g of rosin in due time, naturally cooling the plaster after the plaster is decocted, and spreading and packaging the decocted plaster by adopting a modern process after the plaster is placed for 3 days to form a product.
Example 3:
the raw material medicines of the external traditional Chinese medicine composition comprise the following components: 30g of frankincense, 50g of myrrh, 50g of radix aconiti lateralis preparata, 70g of rhizoma drynariae, 40g of rhizoma smilacis glabrae powder, 50g of pseudo-ginseng, 50g of sappan wood, 30g of mint, 30g of dragon's blood, 50g of caulis spatholobi and 40g of catechu.
Soaking the above materials in 2000g oleum Sesami for 24 hr, penetrating the medicinal effect into oleum Sesami, filtering the oil, filtering to remove residue, decocting oleum Sesami containing the above medicinal components, adding 1200g Colophonium, decocting the plaster, naturally cooling, standing for 3 days, and making into plaster
Example 6:
the raw material medicines of the external traditional Chinese medicine composition comprise the following components: 50g of frankincense, 30g of myrrh, 70g of radix aconiti lateralis preparata, 50g of rhizoma drynariae, 40g of rhizoma smilacis glabrae powder, 30g of pseudo-ginseng, 50g of sappan wood, 30g of mint, 30g of dragon's blood, 50g of caulis spatholobi, 40g of catechu, 10g of safflower, 10g of borneol, 70g of rhizoma cibotii and 30g of angelica dahurica.
Soaking the medicines in 2400g of sesame oil for 24 hours, enabling the medicine effect to permeate into the sesame oil, filtering the oil, filtering out medicine residues, decocting the sesame oil containing the medicine components into condensed oil, adding 1100g of rosin in due time, naturally cooling the plaster after the plaster is decocted, and spreading and packaging the decocted plaster by adopting a modern process after the plaster is placed for 3 days to form a product.
Experimental example 1:
the experimental example is a clinical test, and an experiment was performed using the external preparation of the external Chinese medicinal composition prepared in example 1 or 2.
1. Test object
Selecting 40 patients who come to the hospital and are hospitalized within 1 month, wherein the age of the patients is 44-76 years, 15 male patients and 25 female patients are selected. Among the patients mentioned above, there were 7 cases of arthritis and chondritis due to traumatic injury, 5 cases of joint sprain, 10 cases of lumbar disc herniation and bulging, 5 cases of lumbar degenerative disease, 2 cases of effusion in knee joint, 5 cases of fracture patients, and 6 cases of femoral head necrosis.
2. Treatment regimens
The external application agent with proper amount is applied to the affected part, the dressing is tight, and the medicine is replaced once a day. The treatment effect is judged by oral symptoms of the patient and imaging detection after one day, one week and three weeks of treatment respectively. During treatment, the patient should take care of the injured part to avoid secondary injury during treatment.
The evaluation standard of curative effect is as follows:
and (3) curing: complete resolution of symptoms
The method has the following advantages: the symptoms have basically subsided
And (4) invalidation: no relief of symptoms
3. Results of the experiment
Patients were reviewed after the third week of treatment, with 37 patients with complete regression of symptoms, 3 patients with substantial disappearance of symptoms, and 0 patients with no efficacy. The effective patient is a patient with femoral head necrosis, and due to the long disease period, the patient is subjected to repeated diagnosis after being continuously treated for 3 weeks by the external application agent, and the curative standard is achieved.
The result shows that the cure rate of the external application agent of the invention to the non-open trauma or the femoral head necrosis in one course of treatment is 92.5 percent, and the cure rate of the continuous treatment can reach 100 percent.
4. Typical case
1) Old certain, female, age 66, diagnosed with osteoarthritis of the right knee, right knee joint traumatic arthritis. The pain is improved after one day of treatment by the external application agent; after one week, the joint is not obviously changed after the examination; after three weeks the symptoms completely disappeared upon review. The external application agent of the invention is proved to have obvious curative effect on osteoarthropathy and osteoarticular injury.
2) In 76 years old, it was diagnosed with L1-2 vertebral body end plate osteochondritis, injury of meniscus inside and outside the left knee joint, and left knee joint effusion. After the external application agent is used for treating the diseases for one day, the diseases are not obviously changed; after one week, the centrum is not obviously changed, and the effusion of the left knee joint is reduced; after three weeks, lumbar symptoms are obviously improved, and effusion of the left knee joint basically disappears.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. A topical Chinese medicinal composition is characterized in that the raw materials of the topical Chinese medicinal composition comprise Olibanum, Myrrha, radix Dipsaci, rhizoma Drynariae, rhizoma Smilacis Bockii, Notoginseng radix, lignum sappan, herba Menthae, sanguis Draxonis, caulis Spatholobi and Catechu.
2. The external traditional Chinese medicine composition according to claim 1, wherein the raw materials of the external traditional Chinese medicine composition comprise 3-5 parts by weight of frankincense, 3-5 parts by weight of myrrh, 5-7 parts by weight of discontinuous drugs, 5-7 parts by weight of rhizoma drynariae, 2-4 parts by weight of rhizoma smilacis glabrae powder, 3-5 parts by weight of pseudo-ginseng, 3-5 parts by weight of sappan wood, 3-5 parts by weight of mint, 1-3 parts by weight of dragon's blood, 5-7 parts by weight of caulis spatholobi and 2-4 parts by weight of catechu.
3. The external traditional Chinese medicine composition as claimed in claim 2, wherein the raw materials of the external traditional Chinese medicine composition further comprise 5-7 parts by weight of rhizoma cibotii, 3-5 parts by weight of radix angelicae, 1-3 parts by weight of safflower and 1-2 parts by weight of borneol.
4. The external traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the raw material medicines of the external traditional Chinese medicine composition comprise the following components in parts by weight: 3-5 parts of frankincense, 3-5 parts of myrrh, 5-7 parts of discontinuous drugs, 5-7 parts of rhizoma drynariae, 2-4 parts of buddha's warrior attendant powder, 3-5 parts of pseudo-ginseng, 3-5 parts of sappan wood, 3-5 parts of mint, 1-3 parts of dragon's blood, 5-7 parts of caulis spatholobi, 2-4 parts of catechu, 5-7 parts of rhizoma cibotii, 3-5 parts of radix angelicae, 1-3 parts of safflower and 1-2 parts of borneol.
5. The external traditional Chinese medicine composition according to claim 4, wherein the raw material medicines of the external traditional Chinese medicine composition comprise the following components in parts by weight: 4 parts of frankincense by weight, 4 parts of myrrh by weight, 6 parts of radix aconiti lateralis preparata by weight, 6 parts of rhizoma drynariae by weight, 3 parts of rhizoma smilacis glabrae by weight, 4 parts of pseudo-ginseng by weight, 4 parts of sappan wood by weight, 4 parts of mint by weight, 2 parts of dragon blood by weight, 6 parts of caulis spatholobi by weight, 3 parts of catechu by weight, 6 parts of rhizoma cibotii by weight, 4 parts of radix angelicae by weight, 2 parts of safflower by weight and 1 part of borneol by weight.
6. A Chinese medicinal preparation for external application, which comprises the Chinese medicinal composition for external application as claimed in any one of claims 1 to 5.
7. The traditional Chinese medicine external application agent according to claim 6, wherein the traditional Chinese medicine external application agent is an ointment or powder.
8. The traditional Chinese medicine external application agent according to claim 7, wherein the preparation method of the ointment is as follows: soaking the raw material medicines of the external traditional Chinese medicine composition in 200-250 parts by weight of sesame oil for 24 hours, filtering the oil, filtering out dregs, adding 80-120 parts by weight of rosin, decocting the obtained sesame oil to obtain condensed oil, and naturally cooling to obtain the ointment.
9. Use of the topical Chinese medicinal composition of any one of claims 1-5 or the topical Chinese medicinal preparation of any one of claims 6-8 in the preparation of a medicament for treating non-open trauma or femoral head necrosis.
10. The use according to claim 9, wherein the non-open trauma is closed trauma caused by traumatic injury, closed fracture caused by cumulative strain, or closed fracture caused by disease.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115671237A (en) * | 2022-11-09 | 2023-02-03 | 翟思程 | Formula of external ointment for traumatic injury and preparation method thereof |
| CN116370518A (en) * | 2023-03-13 | 2023-07-04 | 陈名欣 | A topical Chinese medicinal composition for treating bone injury and plastic fixing material for emergency application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1109363A (en) * | 1994-12-27 | 1995-10-04 | 苑庆祝 | Drug for traumatic injury |
-
2020
- 2020-05-22 CN CN202010443337.5A patent/CN111617172A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1109363A (en) * | 1994-12-27 | 1995-10-04 | 苑庆祝 | Drug for traumatic injury |
| CN1060059C (en) * | 1994-12-27 | 2001-01-03 | 苑庆祝 | Drug for traumatic injury |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115671237A (en) * | 2022-11-09 | 2023-02-03 | 翟思程 | Formula of external ointment for traumatic injury and preparation method thereof |
| CN116370518A (en) * | 2023-03-13 | 2023-07-04 | 陈名欣 | A topical Chinese medicinal composition for treating bone injury and plastic fixing material for emergency application |
| CN116370518B (en) * | 2023-03-13 | 2024-06-04 | 陈名欣 | A Chinese medicinal composition for treating fracture by topical application and plastic fixation material composition for emergency application |
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