CN116157125A - 针对bcma的t细胞疗法与免疫调节化合物的组合 - Google Patents

针对bcma的t细胞疗法与免疫调节化合物的组合 Download PDF

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CN116157125A
CN116157125A CN202180044791.6A CN202180044791A CN116157125A CN 116157125 A CN116157125 A CN 116157125A CN 202180044791 A CN202180044791 A CN 202180044791A CN 116157125 A CN116157125 A CN 116157125A
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M·波茨
O·巴图列维奇
N·索尼
J·M·威利福德
M·沃克斯
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Juno Therapeutics Inc
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4214—Receptors for cytokines
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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CN202180044791.6A 2020-04-28 2021-04-27 针对bcma的t细胞疗法与免疫调节化合物的组合 Pending CN116157125A (zh)

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US202063016983P 2020-04-28 2020-04-28
US63/016,983 2020-04-28
PCT/US2021/029503 WO2021222330A2 (en) 2020-04-28 2021-04-27 Combination of bcma-directed t cell therapy and an immunomodulatory compound

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US (1) US20230165872A1 (https=)
EP (1) EP4142723A2 (https=)
JP (1) JP2023524430A (https=)
KR (1) KR20230015921A (https=)
CN (1) CN116157125A (https=)
AU (1) AU2021263765A1 (https=)
BR (1) BR112022021788A2 (https=)
CA (1) CA3181399A1 (https=)
IL (1) IL297688A (https=)
MX (1) MX2022013530A (https=)
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WO2025137751A1 (pt) * 2023-12-26 2025-07-03 Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein Polinucleotídeo, receptor de antígeno quimérico, vetor, composição, método para produção de célula imune efetora modificada e uso do polinucleotídeo

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CA3181399A1 (en) 2021-11-04
AU2021263765A1 (en) 2022-12-01
IL297688A (en) 2022-12-01
KR20230015921A (ko) 2023-01-31
MX2022013530A (es) 2023-02-01
WO2021222330A3 (en) 2021-12-09
US20230165872A1 (en) 2023-06-01
EP4142723A2 (en) 2023-03-08
BR112022021788A2 (pt) 2023-01-17
JP2023524430A (ja) 2023-06-12

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