CN116139215A - Traditional Chinese medicine composition of externally-applied anti-infection traditional Chinese medicine lotion, preparation method and application - Google Patents
Traditional Chinese medicine composition of externally-applied anti-infection traditional Chinese medicine lotion, preparation method and application Download PDFInfo
- Publication number
- CN116139215A CN116139215A CN202310232721.4A CN202310232721A CN116139215A CN 116139215 A CN116139215 A CN 116139215A CN 202310232721 A CN202310232721 A CN 202310232721A CN 116139215 A CN116139215 A CN 116139215A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- traditional chinese
- infection
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 62
- 230000002924 anti-infective effect Effects 0.000 title claims abstract description 36
- 239000000203 mixture Substances 0.000 title claims abstract description 34
- 239000006210 lotion Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 208000015181 infectious disease Diseases 0.000 claims abstract description 17
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 10
- 235000002566 Capsicum Nutrition 0.000 claims abstract description 10
- 239000006002 Pepper Substances 0.000 claims abstract description 10
- 235000016761 Piper aduncum Nutrition 0.000 claims abstract description 10
- 235000017804 Piper guineense Nutrition 0.000 claims abstract description 10
- 235000008184 Piper nigrum Nutrition 0.000 claims abstract description 10
- 240000003705 Senecio vulgaris Species 0.000 claims abstract description 9
- 230000009194 climbing Effects 0.000 claims abstract description 9
- 206010031252 Osteomyelitis Diseases 0.000 claims abstract description 8
- 240000004980 Rheum officinale Species 0.000 claims abstract description 8
- 235000008081 Rheum officinale Nutrition 0.000 claims abstract description 8
- 206010060803 Diabetic foot infection Diseases 0.000 claims abstract description 7
- 244000203593 Piper nigrum Species 0.000 claims abstract 2
- 239000002994 raw material Substances 0.000 claims description 11
- 206010036410 Postoperative wound infection Diseases 0.000 claims description 8
- 208000031650 Surgical Wound Infection Diseases 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 208000004210 Pressure Ulcer Diseases 0.000 claims description 4
- 238000002791 soaking Methods 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 14
- 241000894006 Bacteria Species 0.000 abstract description 5
- 206010052428 Wound Diseases 0.000 abstract description 4
- 208000027418 Wounds and injury Diseases 0.000 abstract description 4
- 208000035143 Bacterial infection Diseases 0.000 abstract description 3
- 208000022362 bacterial infectious disease Diseases 0.000 abstract description 3
- 208000002847 Surgical Wound Diseases 0.000 abstract description 2
- 241000722363 Piper Species 0.000 description 8
- 208000008960 Diabetic foot Diseases 0.000 description 6
- 206010053615 Thermal burn Diseases 0.000 description 6
- 235000003261 Artemisia vulgaris Nutrition 0.000 description 4
- 240000006891 Artemisia vulgaris Species 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 206010012601 diabetes mellitus Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 206010031256 Osteomyelitis chronic Diseases 0.000 description 2
- 241000219061 Rheum Species 0.000 description 2
- 235000009411 Rheum rhabarbarum Nutrition 0.000 description 2
- 240000004534 Scutellaria baicalensis Species 0.000 description 2
- 235000017089 Scutellaria baicalensis Nutrition 0.000 description 2
- 241001146210 Senecio scandens Species 0.000 description 2
- 238000002266 amputation Methods 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010051814 Eschar Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 241000207929 Scutellaria Species 0.000 description 1
- 241000780602 Senecio Species 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 231100000333 eschar Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of traditional Chinese medicine pharmacy, and particularly relates to a traditional Chinese medicine composition of an externally-applied anti-infection traditional Chinese medicine lotion, a preparation method and application thereof. The invention provides a traditional Chinese medicine composition of an externally-applied anti-infective traditional Chinese medicine lotion, which comprises radix sophorae flavescentis, rhizoma atractylodis, folium artemisiae argyi, pepper, paris rhizome, fructus kochiae, radix scutellariae, honeysuckle, climbing groundsel and rheum officinale. The traditional Chinese medicine composition provided by the invention has reasonable formula, has an anti-infection effect, can inhibit and kill bacteria, treats bacterial infection of a wound surface, has small side effect, is widely used in surgical wound surface infection, bone infection and diabetic foot infection, and is worthy of further clinical popularization.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine pharmacy, and particularly relates to a traditional Chinese medicine composition of an externally-applied anti-infection traditional Chinese medicine lotion, a preparation method and application thereof.
Background
Burn and scald cases occur industrially, frequently in national defense and at home, and are characterized clinically by burn wound redness, pain, skin breakage, liquid seepage, eschar, purulence under scab, ulcer formation after liquefaction, scar after healing and scar contracture. Extensive burns can cause shock, local or systemic infections, and improper treatment can cause sepsis.
Diabetic foot is a common complication of diabetes that severely affects the patient's ability to work and quality of life. Diabetic foot ulcers are the main clinical manifestations of diabetic feet, and the amputation rate of the diabetic foot ulcers is 15-20 times that of non-diabetic patients, and researches indicate that the total cause death rate related to amputation of the diabetic patients is increased by more than 5 times compared with that of the non-diabetic patients.
Chronic osteomyelitis is a refractory orthopedic disease with high incidence, deep disease position, serious disease condition, long disease course, poor curative effect and easy repeated attack, and seriously damages the physical and mental health of patients.
At present, antibiotics are generally used for anti-infection of treatment means of burns, scalds, diabetic feet, chronic osteomyelitis and the like, but with the wide use of antibiotics, more and more bacteria have drug resistance, so that the use of the antibiotics is higher and higher, the treatment period is longer and longer, the side effect of liver and kidney is large, the economic burden of patients is increased, and the infection is difficult to thoroughly eliminate. Therefore, the medicine which has good curative effect and few side effects and can resist infection makes up the deficiency of antibiotics and is particularly urgent.
Disclosure of Invention
In view of the above, the invention aims to provide a traditional Chinese medicine composition of an externally-applied anti-infection traditional Chinese medicine lotion, a preparation method and application thereof. The traditional Chinese medicine composition provided by the invention has antibacterial and bactericidal effects, is low in production cost, reasonable in formula, definite in curative effect, convenient to use and free of toxic and side effects, and can be used for effectively treating surgical wound infection.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a traditional Chinese medicine composition of an externally-applied anti-infective traditional Chinese medicine lotion, which comprises the following raw materials in parts by mass: 25-35 parts of kuh-seng, 10-15 parts of rhizoma atractylodis, 20-25 parts of folium artemisiae argyi, 10-15 parts of pepper, 15-20 parts of paris rhizome, 10-15 parts of fructus kochiae, 10-15 parts of radix scutellariae, 10-15 parts of honeysuckle, 10-15 parts of climbing groundsel and 20-30 parts of rheum officinale.
The invention also provides a preparation method of the externally-applied anti-infective traditional Chinese medicine lotion, which comprises the following steps:
the traditional Chinese medicine lotion is prepared by the steps of providing the raw materials of the traditional Chinese medicine composition in the technical scheme, compounding, soaking, extracting liquid medicine and sterilizing at high temperature.
The invention also provides application of the traditional Chinese medicine composition or the traditional Chinese medicine lotion prepared by the preparation method in preparation of anti-infective drugs.
Preferably, the infection includes one or more of a surgical wound infection, a bedsore infection, an osteomyelitis infection, a diabetic foot infection, and a scald infection.
The invention provides a traditional Chinese medicine composition of an externally-applied anti-infective traditional Chinese medicine lotion, which comprises the following raw materials in parts by mass: 25-35 parts of kuh-seng, 10-15 parts of rhizoma atractylodis, 20-25 parts of folium artemisiae argyi, 10-15 parts of pepper, 15-20 parts of paris rhizome, 10-15 parts of fructus kochiae, 10-15 parts of radix scutellariae, 10-15 parts of honeysuckle, 10-15 parts of climbing groundsel and 20-30 parts of rheum officinale. The externally-applied anti-infective Chinese medicinal composition provided by the invention has reasonable formula, has anti-infective effect, can inhibit and kill bacteria, treat wound bacterial infection, has small side effect, is widely used in surgical wound infection, bone infection and diabetic foot infection, and is worthy of great popularization.
Detailed Description
The invention provides a traditional Chinese medicine composition of an externally-applied anti-infective traditional Chinese medicine lotion, which comprises the following raw materials in parts by mass: 25-35 parts of kuh-seng, 10-15 parts of rhizoma atractylodis, 20-25 parts of folium artemisiae argyi, 10-15 parts of pepper, 15-20 parts of paris rhizome, 10-15 parts of fructus kochiae, 10-15 parts of radix scutellariae, 10-15 parts of honeysuckle, 10-15 parts of climbing groundsel and 20-30 parts of rheum officinale.
The traditional Chinese medicine composition of the external anti-infective lotion comprises 25-35 parts of kuh-seng, preferably 28-32 parts, and more preferably 30 parts.
Based on the parts by weight of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 10-15 parts of rhizoma atractylodis, preferably 10-12 parts, and more preferably 10 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 20-25 parts of mugwort leaves, preferably 22 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 10-15 parts of pepper, preferably 12 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 15-20 parts of paris rhizome, preferably 15-18 parts, and more preferably 15 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 10-15 parts of fructus kochiae, preferably 12 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 10-15 parts of baical skullcap root, preferably 12 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 10-15 parts of honeysuckle, preferably 10-12 parts, and more preferably 10 parts.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 10-15 parts of climbing groundsel herb, preferably 10-12 parts of climbing groundsel herb, and more preferably 10 parts of climbing groundsel herb.
Based on the mass parts of the kuh-seng, the external anti-infective Chinese medicinal composition comprises 20-30 parts of rheum officinale, preferably 22-28 parts, and more preferably 25 parts.
The traditional Chinese medicine composition provided by the invention has reasonable formula, has anti-infection effect, can inhibit and kill bacteria, treats bacterial infection of a wound surface, has good curative effect and small side effect, is widely used in surgical wound surface infection, bone infection and diabetic foot infection, and is worth popularizing greatly.
The invention also provides a preparation method of the externally-applied anti-infective traditional Chinese medicine lotion, which comprises the following steps:
the traditional Chinese medicine lotion is prepared by the steps of providing the raw materials of the traditional Chinese medicine composition in the technical scheme, compounding, soaking, extracting liquid medicine and sterilizing at high temperature.
The invention also provides application of the traditional Chinese medicine composition or the traditional Chinese medicine lotion in preparing anti-infective medicines.
In the present invention, the infection preferably includes one or more of a surgical wound infection, a bedsore infection, an osteomyelitis infection, a diabetic foot infection and a scald infection, and more preferably a surgical wound infection.
The traditional Chinese medicine composition or the traditional Chinese medicine lotion has reasonable formula, is widely applicable to patients suffering from surgical wound infection, bedsores, osteomyelitis, diabetic feet and scalds, and has the characteristics of no side effect, difficult recurrence, good curative effect and low cost.
In order to further illustrate the present invention, the following examples are provided to describe in detail the traditional Chinese medicine composition, the preparation method and the application of the external anti-infective traditional Chinese medicine lotion, but they should not be construed as limiting the protection scope of the present invention.
Example 1
The traditional Chinese medicine composition of the externally-applied anti-infection traditional Chinese medicine lotion provided by the embodiment of the invention consists of the following raw materials (1 g is recorded as 1 part): 25 parts of kuh-seng, 10 parts of rhizoma atractylodis, 20 parts of mugwort leaf, 10 parts of pepper, 15 parts of paris rhizome, 10 parts of belvedere fruit, 10 parts of baikal skullcap root, 10 parts of honeysuckle, 10 parts of senecio and 20 parts of rhubarb.
The preparation method of the externally-applied anti-infective traditional Chinese medicine lotion provided by the embodiment of the invention comprises the following steps:
soaking 25g of radix sophorae flavescentis, 10g of rhizoma atractylodis, 20g of folium artemisiae argyi, 10g of pepper, 15g of paris rhizome, 10g of fructus kochiae, 10g of radix scutellariae, 10g of honeysuckle, 10g of senecio scandens and 20g of rheum officinale, extracting liquid medicine, sterilizing at high temperature, and sealing a bottle to obtain the traditional Chinese medicine lotion 1.
Example 2
The traditional Chinese medicine composition of the external anti-infection lotion provided by the embodiment of the invention consists of the following raw materials (1 part is recorded as 1 g): 35 parts of kuh-seng, 15 parts of rhizoma atractylodis, 25 parts of mugwort leaf, 15 parts of pepper, 20 parts of paris rhizome, 15 parts of belvedere fruit, 15 parts of baikal skullcap root, 15 parts of honeysuckle, 15 parts of senecio scandens and 30 parts of rhubarb.
The preparation method of the externally-applied anti-infective traditional Chinese medicine lotion provided by the embodiment of the invention comprises the following steps:
35g of radix sophorae flavescentis, 15g of rhizoma atractylodis, 25g of mugwort leaf, 15g of pepper, 20g of paris rhizome, 15g of fructus kochiae, 15g of radix scutellariae, 15g of honeysuckle, 15g of climbing groundsel and 30g of rheum officinale are soaked, the liquid medicine is extracted, and the liquid medicine is subjected to high-temperature sterilization treatment and bottle sealing, so that the traditional Chinese medicine lotion 2 is obtained.
The invention has the advantages of rich raw materials, simple preparation method, scientific and reasonable raw material compatibility, capability of inhibiting and killing bacteria, small side effect and wide application in surgical wound infection, bone infection and diabetic foot infection.
While the invention has been described in terms of preferred embodiments, it is not intended to be limited thereto, but rather to enable any person skilled in the art to make various changes and modifications without departing from the spirit and scope of the present invention, which is therefore to be limited only by the appended claims.
Claims (4)
1. The traditional Chinese medicine composition of the external anti-infection traditional Chinese medicine lotion is characterized by comprising the following raw materials in parts by mass: 25-35 parts of kuh-seng, 10-15 parts of rhizoma atractylodis, 20-25 parts of folium artemisiae argyi, 10-15 parts of pepper, 15-20 parts of paris rhizome, 10-15 parts of fructus kochiae, 10-15 parts of radix scutellariae, 10-15 parts of honeysuckle, 10-15 parts of climbing groundsel and 20-30 parts of rheum officinale.
2. A preparation method of an externally-applied anti-infective traditional Chinese medicine lotion is characterized by comprising the following steps:
providing the raw materials of the traditional Chinese medicine composition of claim 1, carrying out compound soaking, extracting liquid medicine, and carrying out high-temperature sterilization treatment to obtain the traditional Chinese medicine lotion.
3. The use of the traditional Chinese medicine composition of claim 1 or the traditional Chinese medicine lotion prepared by the preparation method of claim 2 in the preparation of anti-infective drugs.
4. The use according to claim 3, wherein the infection comprises one or more of a surgical wound infection, a bedsore infection, an osteomyelitis infection, a diabetic foot infection and a scalding infection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310232721.4A CN116139215A (en) | 2023-03-13 | 2023-03-13 | Traditional Chinese medicine composition of externally-applied anti-infection traditional Chinese medicine lotion, preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310232721.4A CN116139215A (en) | 2023-03-13 | 2023-03-13 | Traditional Chinese medicine composition of externally-applied anti-infection traditional Chinese medicine lotion, preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116139215A true CN116139215A (en) | 2023-05-23 |
Family
ID=86352516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310232721.4A Pending CN116139215A (en) | 2023-03-13 | 2023-03-13 | Traditional Chinese medicine composition of externally-applied anti-infection traditional Chinese medicine lotion, preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116139215A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102369958A (en) * | 2010-08-18 | 2012-03-14 | 刘智 | Pure natural disinfectant |
| CN105267571A (en) * | 2014-07-11 | 2016-01-27 | 谢兴文 | Anti-inflammatory traditional Chinese medicine lotion |
| CN109908319A (en) * | 2019-04-09 | 2019-06-21 | 彭松云 | The Chinese medicinal lotion for treating hand, sufficient dermal chronic ulcer |
-
2023
- 2023-03-13 CN CN202310232721.4A patent/CN116139215A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102369958A (en) * | 2010-08-18 | 2012-03-14 | 刘智 | Pure natural disinfectant |
| CN105267571A (en) * | 2014-07-11 | 2016-01-27 | 谢兴文 | Anti-inflammatory traditional Chinese medicine lotion |
| CN109908319A (en) * | 2019-04-09 | 2019-06-21 | 彭松云 | The Chinese medicinal lotion for treating hand, sufficient dermal chronic ulcer |
Non-Patent Citations (1)
| Title |
|---|
| 窦群立;杨锋;刘波;李引刚;张根印;杨宁;赵波;: "中药洗剂治疗四肢开放性感染", 中国骨伤, vol. 19, no. 02, pages 5 - 6 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11571452B2 (en) | Method of treating a skin wound with a liquid-state topical pharmaceutical composition | |
| CN103230493B (en) | Traditional Chinese medicine composition for treating unhealed wound | |
| CN105535334A (en) | Radix arnebiae and milkvetch root granulation-promoting extract and preparation method | |
| CN101164574B (en) | Medicine for treating burns and scalds and its preparation method | |
| CN101011487B (en) | Externally used Chinese patent drug for treating burn and scald and its preparation | |
| CN101919927B (en) | Spray for promoting scald healing | |
| CN102357164B (en) | Medicine composition for clinical care of burns and preparation method thereof | |
| CN105168361A (en) | Compound plant oil liniment for treating burns and scalds and preparation method of compound plant oil liniment | |
| CN102716225B (en) | Externally dressed drug for treating burns and scalds | |
| CN1433781A (en) | Wanli ointment | |
| CN116139215A (en) | Traditional Chinese medicine composition of externally-applied anti-infection traditional Chinese medicine lotion, preparation method and application | |
| CN111991471A (en) | A topical Chinese medicinal preparation for treating knife wound, burn and scald, and its preparation method | |
| CN100427118C (en) | Burn and scald medicine | |
| CN113197973A (en) | Pharmaceutical composition and preparation method thereof | |
| CN1072499C (en) | External-use medicine for curing various chronic ulcers | |
| CN113813308A (en) | Medicine for treating burn and scald and preparation method thereof | |
| CN106728069B (en) | Slough-removing and tissue regeneration-promoting paste for treating scalds and burns | |
| CN107714781B (en) | Pharmaceutical composition for treating burns and scalds and preparation method and application thereof | |
| CN107050298A (en) | A kind of Chinese medicine paste formulation and preparation method for treating burn and scald skin damaged | |
| CN1251747C (en) | Medicine for treating burns, scalds, other multiple skin disease and traumatic injury | |
| CN1238012C (en) | Chinese medicine in the form of spray for treating infection of tonsil | |
| CN1401350A (en) | Medicine for treating burns and scald, and producing method thereof | |
| CN101721578A (en) | Traditional Chinese medicine paste for removing necrotic tissue, promoting tissue regeneration and treating burns and scalds | |
| CN107496577A (en) | It is a kind of to be used to treat liquid medicine of scald and preparation method thereof | |
| CN113616707A (en) | Preparation for wound treatment based on 3D printing and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |