CN107496577A - It is a kind of to be used to treat liquid medicine of scald and preparation method thereof - Google Patents
It is a kind of to be used to treat liquid medicine of scald and preparation method thereof Download PDFInfo
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- CN107496577A CN107496577A CN201710674464.4A CN201710674464A CN107496577A CN 107496577 A CN107496577 A CN 107496577A CN 201710674464 A CN201710674464 A CN 201710674464A CN 107496577 A CN107496577 A CN 107496577A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/756—Phellodendron, e.g. corktree
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention provides a kind of liquid medicine for being used to treat scald and preparation method thereof.The liquid medicine includes rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g, coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g.The present invention has probed into the antibacterial ability of each composition and repair to skin based on rigorous laboratory facilities, so as to screen to have obtained this into subassembly, preferred each Ingredient Amount simultaneously, the synergy for the effect of making formation between a variety of natural drugs, it not only ensure that excellent anti-microbial property, it can effectively accelerate wound healing simultaneously, and suppress the formation of scar.On this basis, the present invention develops the preparation method for above prescription drug, this method is with alcohol at normal temperatures to medicinal material derect seething, the dissolution of functional component has been effectively ensured, avoid the phenomenon containing the dregs of a decoction in liquid medicine, it is easy to use, and contains alcoholic content in liquid medicine, ensure that antibacterial effect.
Description
Technical field
The present invention relates to natural medicine technical field, further to the treatment technology of scald, and in particular to one kind is used for
Treat liquid medicine of scald and preparation method thereof.
Background technology
Scald is body injury common in daily production and living, to serious patient, if treating or treating not in time
It is improper, the infection of wound is just easily caused, suppurates, fester, leaves permanent scar, What is more entail dangers to life.Scald
Three Estate, the i.e. only red and swollen distending pain of the skin of first degree scald are generally divided into, skin does not produce without blister；Two degree of scald swelling and pain are difficult
Bear, due to wound and skin corium and trigger bubble；Three degree of scalds are then that pain is not violent sometimes, but injure cortex, subcutaneous fat, bone,
Myoneural, cutaneous necrosis.
At present, the medicine for treating scald is broadly divided into Chinese medicine and the major class of Western medicine two, and its Chinese and Western medicine is in the side such as antibacterial, anti-inflammatory
Face has the function that good, but the recovery for scar is unsatisfactory, and obvious scar, and Western medicine pair can be still left after medication
Liver kidney is metabolized heavy load, and rats after severe scald burn patient should use with caution on the contrary.Chinese medicine it is cheap, have no toxic side effect, curative effect compared with
It is good, but there is also shortcoming, such as：Process is complicated, and the more not easily collecting of composition is complete, so as to lessen the curative effect；To treatment of scald
Overall process pathological characteristic specific aim deficiency, take into account it is whole not enough；Preparation method can not enable the abundant profit of its active ingredient
With.In this case it is necessary to composition improvement is carried out for the scald medicament of natural component, to lift its curative effect.
The content of the invention
A kind of it is contemplated that technological deficiency for prior art, there is provided liquid medicine and its preparation for being used to treat scald
Method, to solve the technical problem of the scald medicament unsatisfactory curative effect of prior art.
Another technical problem to be solved by the present invention is that the scald medicament medication of prior art is inconvenient.
To realize above technical purpose, the present invention uses following technical scheme：
A kind of liquid medicine for being used to treat scald, including following component：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g are yellow
Even 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g.
Preferably, also include 40g Thesium chinese in the liquid medicine.
Preferably, also include 50g Pterospermi Heterophylli in the liquid medicine.
Preferably, also include 20g creeping oxalis in the liquid medicine.
Preferably, also include 80g Chloranthus glaber in the liquid medicine.
Preferably, the liquid medicine consists of the following composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g, the coptis
80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g, Thesium chinese 40g, Pterospermi Heterophylli 50g, creeping oxalis
20g, Chloranthus glaber 80g.
A kind of above-mentioned preparation method for stating liquid medicine, comprises the following steps：The composition of formula ratio is taken to be soaked in 75% mass point
In several alcohol, filtered after soaking 20d, it is the liquid medicine for being used to treat scald to take filtrate.
In the above technical scheme rheum officinale, Chinese gall, the fruit of Chinese magnoliavine, the coptis, golden cypress, garden burnet, giant knotweed, calcined Dragon's bone, borneol,
Thesium chinese, Pterospermi Heterophylli, creeping oxalis, Chloranthus glaber are natural medicinal ingredients, and its respective limiting meaning should be according to traditional Chinese medicine technology
The general understanding level in field is explained；The weight of each composition refers both to its dry weight.
In above technical scheme, immersion of each composition in alcohol can directly be soaked with the native state of each composition
Row immersion again after the process such as bubble or sliced, crushing；As long as the effect of that is meeting each natural drug
Composition dissolution just belongs to technical scheme into alcohol.The use of liquid medicine can be that directly embrocate can also in affected part
It is to the direct sprinkling in affected part or elution, its specifically used method can also be entered according to the conventional externally applied drug application method of this area
OK, the restriction effect to medicine of the present invention and preparation method thereof is not formed.
In above technical scheme, rheum officinale heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, removing dampness through diuresis and removing jaundice；Five
Gall nut is astringed the lung, puckery intestines, is stopped blooding, and removing toxic substances, is mainly used in the diseases such as chronic cough of deficiency lung, protracted dysentery；The fruit of Chinese magnoliavine is astringed the lung, nourshing kidney, cures mainly deficiency syndrome of the lung asthma
Cough, thirst, spontaneous perspiration, night sweat etc.；The coptis and golden cypress have a purging intense heat, eliminating dampness, removing toxic substances, clinically main to use the effect of desinsection
In hot dysentery, diarrhea, quench one's thirst, jaundice , crippling wilts etc.；Garden burnet is used for blood in cool blood, clearing heat and detoxicating；Giant knotweed cures mainly arthralgia pain due to rheumatism, carbuncle swells
Sore；Calcined Dragon's bone be used in the prior art primarily to treat frightened epilepsy it is demented, palpitation is forgetful；And borneol then plays logical all keys, dissipate strongly fragrant
The effect of fire.As can be seen here, the main component selected of the present invention is mainly medicine for oral administration in the prior art, and generally with scald
Treat unrelated.The present invention has probed into the antibacterial ability of each composition and to skin based on rigorous laboratory facilities in this case
The repair of skin, so as to screen to have obtained this into subassembly, while preferred each Ingredient Amount, make a variety of natural drugs it
Between the effect of being formed synergy, not only ensure that excellent anti-microbial property, while can effectively accelerate wound healing, and press down
The formation of scar processed.
In optimal technical scheme, present invention discover that by further adding Thesium chinese, Pterospermi Heterophylli, creeping oxalis, Chloranthus glaber
Therapeutic effect can be further lifted Deng natural herbal, while helps to reduce excitant of the prescription to skin.On this basis,
The present invention develops the preparation method for above prescription drug, and this method, at normal temperatures to medicinal material derect seething, has with alcohol
Effect ensure that the dissolution of functional component, avoid the phenomenon containing the dregs of a decoction in liquid medicine, be easy to use, and contain wine in liquid medicine
Smart composition, ensure that antibacterial effect.The present invention realizes prominent technique effect, while cost with the technological improvement of novelty
It is relatively low, be easily achieved, therefore there is good promotion prospect.
Embodiment
The embodiment of the present invention will be described in detail below.In order to avoid excessive unnecessary details,
It is will not be described in detail in following examples to belonging to known structure or function.
Approximating language used in following examples can be used for quantitative expression, show do not changing basic function
In the case of quantity can be allowed to have certain variation.Therefore, the numerical value corrected with the language such as " about ", " left and right " is not limited to this
Exact value is in itself.In certain embodiments, the numerical value for " about " representing to allow it to correct is in positive and negative 10 (10%)
In the range of change, such as, " about 100 " represent can be any numerical value between 90 to 110.In addition, " about first
Numerical value is to second value " statement in, at about correct the first and second numerical value two values.In some cases, it is approximate
Language may be relevant with the precision of measuring instrument.
In addition to being defined, technology used and scientific terminology have and art technology of the present invention in following examples
The identical meanings that personnel are commonly understood by.
Embodiment 1
A kind of liquid medicine for being used to treat scald, is consisted of the following composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g,
Coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g.
A kind of preparation method of above-mentioned liquid medicine, comprises the following steps：The composition of formula ratio is taken to be soaked in 75% mass fraction
Alcohol in, filtered after soaking 20d, it is the liquid medicine for being used to treat scald to take filtrate.
Using above liquid medicine scald the treatment of patient, situation is as follows.
Case 1：Mr. Li, male, 36 years old, in scalding right arm in 2016, surface of a wound area about 4cm × 8cm.Afterwards
Treatment (2h/ times) is sprayed through the present embodiment liquid medicine, continued treatment is fully recovered after one week, does not stay scar.
Case 2：Slowly so-and-so, female, 7 years old, is scalded, surface of a wound area about 6cm × 12cm is (deep for 2017 by just boiled thin rice gruel
II degree).Treated by being sprayed through the present embodiment liquid medicine, continued treatment is fully recovered after 14 days, so far without any symptom.
Embodiment 2
A kind of liquid medicine for being used to treat scald, is consisted of the following composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g,
Coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g, Pterospermi Heterophylli 50g.
Embodiment 3
A kind of liquid medicine for being used to treat scald, is consisted of the following composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g,
Coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g, Thesium chinese 40g, creeping oxalis 20g.
Embodiment 4
A kind of liquid medicine for being used to treat scald, is consisted of the following composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g,
Coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g, Pterospermi Heterophylli 50g, creeping oxalis 20g, careless coral
Coral 80g.
Embodiment 5
A kind of liquid medicine for being used to treat scald, is consisted of the following composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g,
Coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g, Thesium chinese 40g, Pterospermi Heterophylli 50g, jealous woman slurry
Careless 20g, Chloranthus glaber 80g.
Embodiment 6
The present embodiment is used to investigate the therapeutic effect that embodiment 5 provides liquid medicine.
Clinical practice to the patient of 100 treatment scalds, achieves the effect of preferable, total effective rate has up to 100%
Closing clinical treatment situation, details are as follows：
1st, administrated method：Liquid medicine is directly sprayed to affected part or directly eluted, natural air drying, 4 times a day.
2nd, efficacy evaluation
1. fully recover：Symptom disappears.
It is 2. effective：There is not recurrence after healing.
It is 3. invalid：Pretherapy and post-treatment effect change is little.
3rd, efficacy analysis：
1. sex：Treatment scald patient 100, wherein male's 60 (60%) altogether, women 40 (40%).
2. scald grade：First degree scald 30, two degree are scalded 40, and three degree are scalded 30.
3. age group：2~20 years old 30,20~40 years old 20,41~60 years old 20, more than 60 years old 30.
The treatment effectiveness evaluation table of table 1
By the liquid medicine treatment scald sufferer of the present invention, the effect of satisfied have received.The sick symptom is a lot, this
Clinical trial is divided into " first degree scald ", " two degree of scalds " and " three degree of scalds " several types, the clinical trial according to clinical characters
Carried out jointly in general hospital and special outpatient clinic.
Before the treatment of this group of case, most of patients carried out in, the treatment of doctor trained in Western medicine mode, but do not obtain the effect of preferable,
Especially Western medicine side effect is larger, and different injuries are caused to human body.During the liquid medicine of the external application present invention, it must not be used
Its treatment of scald medicine.
Scald lotion of the present invention cures mainly boiling hot various meals, having one's hair waved, oily boiling hot, pitch scald and chemical substance burn and scald etc.,
Scar is not stayed, no infection, does not sterilize, does not wrap up.Cost is cheap easy to use, suitable for remote town and country, shortage of medical services and medicines place.It is vertical
Take vertical use, analgesic is fast, more after do not stay scar, evident in efficacy, drug effect safety and stability, cure rate is high, without any side effects.It is sick light
Person 5~7 days, sick severe one first quarter moon can fully recover.
Embodiments of the invention are described in detail above, but the content is only presently preferred embodiments of the present invention,
It is not intended to limit the invention.All all any modification, equivalent and improvement done in the application range of the present invention etc.,
It should be included within protection scope of the present invention.
Claims (7)
1. a kind of liquid medicine for being used to treat scald, it is characterised in that including following component：Rheum officinale 50g, Chinese gall 100g, the fruit of Chinese magnoliavine
100g, coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone 100g, borneol 20g.
A kind of 2. liquid medicine for being used to treat scald according to claim 1, it is characterised in that the also Thesium chinese including 40g.
A kind of 3. liquid medicine for being used to treat scald according to claim 1, it is characterised in that the also Pterospermi Heterophylli including 50g.
A kind of 4. liquid medicine for being used to treat scald according to claim 1, it is characterised in that the also creeping oxalis including 20g.
A kind of 5. liquid medicine for being used to treat scald according to claim 1, it is characterised in that the also Chloranthus glaber including 80g.
6. a kind of liquid medicine for being used to treat scald according to claim 1, it is characterised in that the liquid medicine is by following component
Composition：Rheum officinale 50g, Chinese gall 100g, fruit of Chinese magnoliavine 100g, coptis 80g, golden cypress 80g, garden burnet 50g, giant knotweed 50g, calcined Dragon's bone
100g, borneol 20g, Thesium chinese 40g, Pterospermi Heterophylli 50g, creeping oxalis 20g, Chloranthus glaber 80g.
7. the preparation method of any one of a kind of claim 1~6 liquid medicine, it is characterised in that comprise the following steps：Take formula
The composition of amount is soaked in the alcohol of 75% mass fraction, is filtered after soaking 20d, takes filtrate is as described to be used to treat scald
Liquid medicine.
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Application publication date: 20171222 |