CN116077566B - Chinese herbal medicine composition for promoting oestrus of cows and preparation method thereof - Google Patents
Chinese herbal medicine composition for promoting oestrus of cows and preparation method thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
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Abstract
The invention discloses a Chinese herbal medicine composition for promoting oestrus of cows and a preparation method thereof, and relates to the technical field of traditional Chinese medicine formulas. The traditional Chinese medicine composition comprises the following components in parts by weight: 40-60 parts of clove, 40-60 parts of pericarpium zanthoxyli, 40-60 parts of actinolite, 40-60 parts of cherokee rose fruit, 40-60 parts of cuttlebone, 50-70 parts of cistanche salsa, 40-60 parts of dried alum, 30-50 parts of borneol and 900-1100 parts of beef cattle essence feed. The invention can repair the organic diseases of the reproductive system of cows with general properties, promote the oestrus of the cows and improve the conception rate, thereby improving the oestrus rate of groups.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine formulas, in particular to a Chinese herbal medicine composition for promoting oestrus of cows and a preparation method thereof.
Background
The method is an important index for the high-quality development and reproduction rate of beef industry, and ensures that the high-efficiency reproduction is the embodiment of the high-quality development. One calf obtained 12 months later is a standardized healthy breeding, and is also a sign of high-quality development. The low reproduction rate has become a big obstacle for the development of beef cattle industry at present; the beef cattle has a plurality of factors causing low oestrus rate, such as congenital factors, nutrition deficiency, low oestrus rate caused by propagation disorder infectious diseases and the like, and an effective oestrus technology means is needed to solve and improve the problems.
The prior art mainly comprises the following steps: 1. the oestrus rate is improved by using oestrus feed, the technical mode is popularized and used in wide beef cattle cultivation areas, the main mode is oestrus feed, postpartum cows are fed, and the oestrus rate is improved; 2. the injection of chemical hormone medicines to calving cows can raise ovulation quantity and oestrus rate, which is a hormone-guided oestrus technology, and the method takes effect quickly and is commonly used for oestrus and synchronous oestrus. 3. The Chinese herbal medicine aphrodisiac technology comprises the following steps: there are also various kinds of Chinese herbal medicine products such as aphrodisiac in the market, and the Chinese herbal medicine products are mixed into feed to feed cows, so that oestrus rate is improved.
The oestrus of cows has a very close relationship with the nutritional status and health of the reproductive system. In particular, the insufficient content of several nutrients related to reproduction may cause problems such as lack of oestrus, low conception rate, etc. Therefore, the improvement of oestrus rate can supplement sufficient nutrients such as vitamins, selenium, manganese, copper and other trace elements, and the problems of oestrus failure, false oestrus and the like are caused if organic diseases of a reproductive system such as endometritis, ovarian cyst, hormone disturbance and the like exist. The estrus-inducing feed has a general use effect in the group with good fat condition, and is not suitable for all groups;
at present, the Western medicine technology is mainly used for promoting oestrus, but the Western medicine treatment method is mainly used for treating symptoms but not root causes, has great side effects, is often used for the first time, then shows decreasing effect, finally does not act or doubles the dosage, causes accumulation of chemical substances in the body, causes hormone disorder, and finally can only eliminate the cow. The accumulation of chemicals can also jeopardize the health of the human body through the food chain.
The traditional Chinese veterinary medicine market is filled with inferior veterinary medicines or false veterinary medicines with low or no drug effect, and the effect of products on the market is poor or no. Therefore, the classical proved recipe which is possibly effective has no effect because of using inferior Chinese herbal medicines, and the merchant only selects a few medicinal materials for reducing the cost, so that the effect is also not ideal.
Therefore, it is an urgent need to solve the problems of the skilled in the art to provide a Chinese herbal medicine composition for promoting oestrus of cows and a preparation method thereof.
Disclosure of Invention
In view of the above, the present invention provides a Chinese herbal medicine composition for promoting oestrus of cows and a preparation method thereof.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
a Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 40-60 parts of clove, 40-60 parts of pericarpium zanthoxyli, 40-60 parts of actinolite, 40-60 parts of cherokee rose fruit, 40-60 parts of cuttlebone, 50-70 parts of cistanche salsa, 40-60 parts of dried alum, 30-50 parts of borneol and 900-1100 parts of beef cattle essence feed.
Further, the traditional Chinese medicine composition comprises the following components in parts by weight: 50 parts of clove, 50 parts of pericarpium zanthoxyli, 50 parts of actinolite, 50 parts of cherokee rose fruit, 50 parts of cuttlebone, 60 parts of cistanche salsa, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle essence feed.
Clove: pungent taste and warm nature; the main functions are as follows: has effects of warming middle energizer, lowering adverse qi, invigorating kidney and supporting yang. Can be used for treating deficiency-cold of spleen and stomach, singultus, emesis, anorexia, vomiting and diarrhea, cold pain of heart and abdomen, and sexual impotence due to kidney deficiency.
Pericarpium Zanthoxyli: pungent taste and warm nature; the main functions are as follows: warm middle energizer to alleviate pain, kill parasites and relieve itching. Can be used for treating abdominal cold pain, emesis, diarrhea, and abdominal pain due to accumulation of parasites; it is used externally to treat eczema and pruritus vulvae.
Actinolite: salty taste, warm nature; the main functions are as follows: warming kidney and strengthening yang. Is used for treating deficiency of kidney-yang, sexual impotence, spermatorrhea, premature ejaculation, soreness of waist and knees, infertility due to cold womb, leukorrhagia, abdominal mass, and metrorrhagia.
Cherokee rose fruit: sour, sweet and astringent, and neutral in nature; the main functions are as follows: to arrest spontaneous emission and reduce urination, arrest spontaneous collapse and stop leukorrhagia, astringe intestines and check diarrhea. It can be used for treating spermatorrhea, enuresis, frequent urination, metrorrhagia, leukorrhagia, and chronic diarrhea and dysentery.
Cuttlebone: salty and astringent taste, warm nature; the main functions are as follows: astringing to stop bleeding, astringing essence to stop leukorrhagia, relieving hyperacidity and pain, astringing dampness and healing sore. Can be used for treating hematemesis, epistaxis, metrorrhagia, hematochezia, spermatorrhea, leucorrhea with reddish discharge, and gastralgia; it is used to treat hemorrhage due to injury, eczema, wet sore, and ulcer.
Cistanche deserticola: sweet, sour, salty, warm; the main functions are as follows: tonify kidney, nourish essence, moisten dryness and smooth intestine. Can be used for treating sexual impotence, infertility, leukorrhagia, metrostaxis, lumbago, gonalgia, and constipation due to blood dryness.
Drying alum: sour and astringent taste, cold nature; the main functions are as follows: eliminating phlegm, eliminating dampness, relieving diarrhea, stopping bleeding, removing toxic substances, and killing parasites. It is used for treating epilepsy, pharyngitis, guilt, excessive salivation, hepatitis, jaundice, yellow swelling, gastric ulcer, duodenal ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha, sore, hemorrhoid, scabies, water injury, fire injury, and insect injury.
Borneol: pungent and bitter in flavor and slightly cold in nature; has effects of inducing resuscitation, refreshing mind, relieving swelling and pain, and clearing away heat and toxic materials. Can be used for treating various unconsciousness, no matter heat blockage or cold blockage
Beef cattle essence feed: belongs to concentrate supplement for beef cattle and complete feed, and has the effects: 1. supplementing nutrients; 2. as a drug carrier; 3. plays a role in improving palatability.
The medicine proportioning relation of the invention is as follows:
monarch drug: clove and pricklyash peel, pericarpium zanthoxyli, having the effect of warming spleen and stomach and stopping cold womb
Ministerial drugs: actinolitum and fructus Rosae Laevigatae-yang-tonifying and essence-extracting
Adjuvant drug: cuttlebone and cistanche deserticola, qi invigorating and essence replenishing
The preparation method comprises the following steps: calcined alum, borneol, heat of monarch drug
A preparation method of a Chinese herbal medicine composition for promoting oestrus of cows comprises the following steps:
(1) Selecting the following drugs: preparing materials according to Chinese herbal medicines in a formula;
(2) Powdering: uniformly pulverizing the mixed Chinese herbal medicines in an ultrafine pulverizer to 100 meshes;
(3) Mixing: stirring and uniformly mixing the beef cattle concentrate supplement in a feed stirrer;
(4) Granulating: preparing the mixed feed and the medicine into feed granules containing the medicine;
(5) And (3) packaging: the granules were packed in 1.4 kg/bag.
Compared with the prior art, the invention has the beneficial effects that:
the Chinese veterinary theory claims to treat both principal and secondary aspect of disease, adopts purely natural and residue-free traditional Chinese medicinal materials to treat the aphrodisiac and promote the aphrodisiac, can repair the general problems of the reproductive system of beef cattle, promotes the aphrodisiac, and is the most feasible effective method for improving the overall reproductive efficiency. The Chinese herbal medicine formula adopted in the invention has definite curative effect after years of practical use. Mainly solves the treatment and estrus promotion effects of refractory non-estrus cows 2 months and above after calving, is firstly suitable for the non-estrus problem of cows in all feeding modes, has no side effects, is natural, green and pollution-free, and cannot remain in the body to cause food safety; moreover, the high-standard Chinese herbal medicines with the same medicine content are adopted, so that the curative effect is definite, the organic diseases of the reproductive system of the cows with general properties can be repaired, the oestrus of the cows is promoted, the conception rate is improved, and the oestrus rate of groups is improved, so that the technology and the products have great market application prospects. Can solve the problem of low reproduction rate in the development of beef cattle industry.
The invention adopts the traditional Chinese veterinary theory, and the clove treats deficiency-cold in spleen and stomach, singultus and vomit, anorexia, vomiting and diarrhea, psychroalgia of heart and abdomen, kidney deficiency and impotence; fructus Zanthoxyli is used for treating deficiency-cold of spleen and stomach, singultus, emesis, anorexia, vomiting and diarrhea, cold pain of heart and abdomen, and sexual impotence due to kidney deficiency; actinolite is used for treating deficiency of kidney-yang, sexual impotence, spermatorrhea, premature ejaculation, soreness of waist and knees, infertility due to cold womb, leukorrhagia, abdominal mass, metrorrhagia; cherokee rose fruit is used for seminal emission, spermatorrhea, enuresis, frequent urination, metrorrhagia, leukorrhagia, chronic diarrhea and chronic dysentery; cuttlebone is used for hematemesis, epistaxis, metrorrhagia, hematochezia, spermatorrhea, leucorrhea with red and white discharge, and stomach ache and acid regurgitation; external treatment of injury bleeding, eczema, wet sore and unhealed ulcer; cistanche deserticola is mainly used for treating impotence, infertility, leukorrhagia, metrostaxis, cold pain of waist and knee, and constipation due to blood dryness; the dried alum is mainly used for treating epilepsy, pharyngitis, guilt and excessive salivation, hepatitis, jaundice, yellow swelling, gastric ulcer, duodenal ulcer, uterine prolapse, leucorrhea, diarrhea, epistaxis, aphtha, sore of mouth and tongue, sore hemorrhoids, mange, water, fire and insect injury; borneol can be used for various unconsciousness symptoms, and can be used for both heat blockage and cold blockage. The medicine combination has obvious curative effect, and the medicine combination has good curative effect both in decoction and superfine powder. In addition, the preparation process of the Chinese herbal medicine preparation is simple, and the problem of difficult administration route and the problem of accurate administration are solved after the Chinese herbal medicine preparation is prepared into feed granules. In a word, the invention has the advantages of obvious treatment effect, effective improvement of oestrus rate of beef cattle and no residue in vivo.
Detailed Description
The following description of the technical solutions in the embodiments of the present invention will be clear and complete, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 50 parts of clove, 50 parts of pericarpium zanthoxyli, 50 parts of actinolite, 50 parts of cherokee rose fruit, 50 parts of cuttlebone, 60 parts of cistanche salsa, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle essence feed.
The preparation method comprises the following steps:
(1) Selecting the following drugs: preparing materials according to Chinese herbal medicines in a formula;
(2) Powdering: uniformly pulverizing the mixed Chinese herbal medicines in an ultrafine pulverizer to 100 meshes;
(3) Mixing: stirring and uniformly mixing the beef cattle concentrate supplement in a feed stirrer;
(4) Granulating: preparing the mixed feed and the medicine into feed granules containing the medicine;
(5) And (3) packaging: the granules were packed in 1.4 kg/bag.
Example 2
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 40 parts of clove, 40 parts of pericarpium zanthoxyli, 40 parts of actinolite, 40 parts of cherokee rose fruit, 40 parts of cuttlebone, 50 parts of cistanche salsa, 40 parts of dried alum, 30 parts of borneol and 1080 parts of beef cattle essence.
The preparation method is the same as in example 1.
Example 3
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 60 parts of clove, 60 parts of pericarpium zanthoxyli, 60 parts of actinolite, 60 parts of cherokee rose fruit, 60 parts of cuttlebone, 70 parts of cistanche salsa, 60 parts of dried alum, 50 parts of borneol and 920 parts of beef cattle essence feed.
The preparation method is the same as in example 1.
Comparative example 1
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 100 parts of clove, 100 parts of pericarpium zanthoxyli, 50 parts of cuttlebone, 60 parts of cistanche, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle essence feed.
The preparation method is the same as in example 1.
Comparative example 2
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 100 parts of actinolite, 100 parts of cherokee rose fruit, 50 parts of cuttlebone, 60 parts of cistanche salsa, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle essence feed.
The preparation method is the same as in example 1.
Comparative example 3
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 100 parts of clove, 100 parts of actinolite, 50 parts of cuttlebone, 60 parts of cistanche, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle essence feed.
The preparation method is the same as in example 1.
Comparative example 4
A Chinese herbal medicine composition for promoting oestrus of cows comprises the following components in parts by weight: 100 parts of pericarpium zanthoxyli, 100 parts of cherokee rose fruit, 50 parts of cuttlebone, 60 parts of cistanche salsa, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle essence feed.
The preparation method is the same as in example 1.
Animal experiment 1
Trial test 240 of each formula of Chinese herbal medicines is carried out in Toron county and Zhenglan flag of the Meng Guxi Lin Guole Union, cows which do not have oestrus after delivery for more than 2 months are taken as experimental objects, the pharmaceutical formulas of examples 1-3 and comparative examples 1-4 are prepared into drug-containing particles, the blank control is fed with beef cattle concentrate feed, each dose is fed for 1.4kg, 3 times and 1 bag each time are continuously fed, and corresponding experimental effects are obtained after 1 pair (3 bags) of administration is completed, and the following table 1:
using examples 1-3, comparative examples 1-4, 3 bags per head of cows that were not oestrus for more than 2 months after delivery were fed with 1 side drug, and oestrus effects were observed within 15 days.
Table 1: estrus effect within 15 days of administration
| Examples | State before use | Number of heads | Dosage of | Number of oestrus | Estrus rate |
| Example 1 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 29 | 96.7％ |
| Example 2 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 25 | 83.3％ |
| Example 3 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 27 | 90％ |
| Comparative example 1 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 18 | 60％ |
| Comparative example 2 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 12 | 40％ |
| Comparative example 3 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 20 | 66.7％ |
| Comparative example 4 | Aphasia after 2 months | 30 | 3 bags are a pair of medicines, and 3 bags are given to each head | 21 | 70％ |
| Blank control | Aphasia after 2 months | 30 | 1.4kg per ton, feeding for 3 times continuously | 5 | 16.7％ |
The results show that the optimal formula is selected as example 1, and the oestrus rate is 96.7%. Comparative example 1 was free of two ministerials, actinolite and cherokee rose, and had no effect of supporting yang and improving sperm; comparative example 2 has no effect of warming and stopping cold in uterus without adding two monarch drugs of clove and pericarpium zanthoxyli; comparative example 3 was free of added pericarpium zanthoxyli and fructus rosae laevigatae, and comparative example 4 was added flos caryophylli and actinolite, and although the monarch and minister collocation is available, the drug property is single, so that the oestrus rate is not as good as that of examples 1-3 of the invention.
Animal experiment 2
The granules of the Chinese herbal medicine composition prepared in example 1 of the present application were used in the popularization of the Chinese herbal medicine composition granules prepared in example 1 of the present application in the middle right flag of the family of the Engineers, the Etoque flag of the Etoque, the Zhenglan flag, the Zhengban white flag, the Xuelinghaote city, the Balina right flag of the Ching city, the Etoque flag of the Etoque city, and the Utility flag of the Engineer, the total number of experimental cows was 400, the Chinese herbal medicine composition prepared in example 1 was continuously fed 3 times, 1 bag each time, and the total estrus number reached 358.
Table 2: estrus effect within 15 days of administration
The cows using the estrus-inducing drug particles are all over 2 months old after delivery, the longest is Su Bainiu which does not heat for over 1 year, the total estrus effective rate reaches 90% on the 3 rd to 15 th days after the drug particles are used, the estrus efficiency is low in 7 months and 8 months from the use season, the estrus rates of the rest months are high from the whole effect, the analysis reasons are possibly related to heat stress of the cows, and no obvious difference exists in other months.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (3)
1. The traditional Chinese medicine composition for promoting oestrus of cows is characterized by comprising the following components in parts by weight: 40-60 parts of clove, 40-60 parts of pericarpium zanthoxyli, 40-60 parts of actinolite, 40-60 parts of cherokee rose fruit, 40-60 parts of cuttlebone, 50-70 parts of cistanche salsa, 40-60 parts of dried alum, 30-50 parts of borneol, and 900-1100 parts of beef cattle concentrate supplement.
2. The traditional Chinese medicine composition for promoting oestrus of cows according to claim 1, which is characterized by comprising the following components in parts by weight: 50 parts of clove, 50 parts of pericarpium zanthoxyli, 50 parts of actinolite, 50 parts of cherokee rose fruit, 50 parts of cuttlebone, 60 parts of cistanche salsa, 50 parts of dried alum, 40 parts of borneol and 1000 parts of beef cattle concentrate supplement.
3. The method for preparing the traditional Chinese medicine composition for promoting oestrus of cows as claimed in claim 1, which is characterized by comprising the following steps:
(1) Selecting the following drugs: preparing materials according to traditional Chinese medicines in a formula;
(2) Powdering: uniformly pulverizing the mixed Chinese medicines in an ultrafine pulverizer to 100 meshes;
(3) Mixing: stirring and uniformly mixing the beef cattle concentrate supplement in a feed stirrer;
(4) Granulating: preparing the mixed feed and the medicine into feed granules containing the medicine;
(5) And (3) packaging: the granules were packed in 1.4 kg/bag.
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| CN110432383A (en) * | 2019-08-09 | 2019-11-12 | 内蒙古自治区农牧业科学院 | It is a kind of to promote the sexual maturity the mongolian veterinary drug additive and preparation method thereof of progestogenic for ewe |
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