CN116035964A - Edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, preparation method and application - Google Patents
Edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, preparation method and application Download PDFInfo
- Publication number
- CN116035964A CN116035964A CN202211098665.1A CN202211098665A CN116035964A CN 116035964 A CN116035964 A CN 116035964A CN 202211098665 A CN202211098665 A CN 202211098665A CN 116035964 A CN116035964 A CN 116035964A
- Authority
- CN
- China
- Prior art keywords
- traditional chinese
- chinese medicine
- pigment
- lipstick
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 104
- 239000000284 extract Substances 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 31
- 239000000049 pigment Substances 0.000 claims abstract description 71
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 32
- 238000002156 mixing Methods 0.000 claims abstract description 27
- 235000000177 Indigofera tinctoria Nutrition 0.000 claims abstract description 24
- 229940097275 indigo Drugs 0.000 claims abstract description 24
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 claims abstract description 24
- SEBIKDIMAPSUBY-ARYZWOCPSA-N Crocin Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)C(C)=CC=CC(C)=C\C=C\C=C(/C)\C=C\C=C(C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SEBIKDIMAPSUBY-ARYZWOCPSA-N 0.000 claims abstract description 21
- 239000009627 gardenia yellow Substances 0.000 claims abstract description 21
- 239000001052 yellow pigment Substances 0.000 claims abstract description 21
- WLYGSPLCNKYESI-RSUQVHIMSA-N Carthamin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1[C@@]1(O)C(O)=C(C(=O)\C=C\C=2C=CC(O)=CC=2)C(=O)C(\C=C\2C([C@](O)([C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)C(O)=C(C(=O)\C=C\C=3C=CC(O)=CC=3)C/2=O)=O)=C1O WLYGSPLCNKYESI-RSUQVHIMSA-N 0.000 claims abstract description 19
- DYQVDISPPLTLLR-HJQYTNQXSA-N Carthamin Natural products CC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)[C@]2(O)C(=C(C=C/3C(=O)C(=C(O)[C@](O)([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C3=O)C(=O)C=Cc5ccc(O)cc5)C(=O)C(=C2O)C(=O)C=Cc6ccc(O)cc6)O DYQVDISPPLTLLR-HJQYTNQXSA-N 0.000 claims abstract description 19
- 239000000203 mixture Substances 0.000 claims abstract description 19
- 241000229143 Hippophae Species 0.000 claims abstract description 18
- 241000628997 Flos Species 0.000 claims abstract description 15
- 241000228347 Monascus <ascomycete fungus> Species 0.000 claims abstract description 15
- 108010053210 Phycocyanin Proteins 0.000 claims abstract description 14
- 239000000843 powder Substances 0.000 claims abstract description 12
- 241000756943 Codonopsis Species 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 4
- 239000009636 Huang Qi Substances 0.000 claims abstract description 3
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 36
- 150000001875 compounds Chemical class 0.000 claims description 33
- 239000000341 volatile oil Substances 0.000 claims description 26
- 238000010298 pulverizing process Methods 0.000 claims description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 238000001035 drying Methods 0.000 claims description 19
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 18
- 239000006228 supernatant Substances 0.000 claims description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 16
- 238000007873 sieving Methods 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 15
- 239000000314 lubricant Substances 0.000 claims description 13
- 230000001105 regulatory effect Effects 0.000 claims description 13
- 239000003906 humectant Substances 0.000 claims description 12
- 239000000706 filtrate Substances 0.000 claims description 11
- 239000011159 matrix material Substances 0.000 claims description 11
- 241001313855 Bletilla Species 0.000 claims description 10
- 239000000796 flavoring agent Substances 0.000 claims description 10
- 235000013355 food flavoring agent Nutrition 0.000 claims description 10
- 238000000227 grinding Methods 0.000 claims description 10
- 239000001993 wax Substances 0.000 claims description 10
- 235000007189 Oryza longistaminata Nutrition 0.000 claims description 9
- 240000007594 Oryza sativa Species 0.000 claims description 9
- 235000007164 Oryza sativa Nutrition 0.000 claims description 9
- 238000007710 freezing Methods 0.000 claims description 9
- 238000002386 leaching Methods 0.000 claims description 9
- 238000000643 oven drying Methods 0.000 claims description 8
- 244000144725 Amygdalus communis Species 0.000 claims description 7
- 235000011437 Amygdalus communis Nutrition 0.000 claims description 7
- 239000008168 almond oil Substances 0.000 claims description 7
- 238000001816 cooling Methods 0.000 claims description 7
- 235000013399 edible fruits Nutrition 0.000 claims description 7
- 235000011187 glycerol Nutrition 0.000 claims description 7
- 239000002608 ionic liquid Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 235000008390 olive oil Nutrition 0.000 claims description 7
- 239000004006 olive oil Substances 0.000 claims description 7
- 239000007787 solid Substances 0.000 claims description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 6
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 6
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 6
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 6
- 235000003935 Hippophae Nutrition 0.000 claims description 6
- 244000044822 Simmondsia californica Species 0.000 claims description 6
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 6
- 235000006533 astragalus Nutrition 0.000 claims description 6
- 230000008014 freezing Effects 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 6
- 238000010257 thawing Methods 0.000 claims description 6
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 5
- 244000061520 Angelica archangelica Species 0.000 claims description 5
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 5
- 244000068988 Glycine max Species 0.000 claims description 5
- 235000010469 Glycine max Nutrition 0.000 claims description 5
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 5
- 239000004166 Lanolin Substances 0.000 claims description 5
- 241000234435 Lilium Species 0.000 claims description 5
- 244000246386 Mentha pulegium Species 0.000 claims description 5
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 5
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 5
- 244000236658 Paeonia lactiflora Species 0.000 claims description 5
- 235000008598 Paeonia lactiflora Nutrition 0.000 claims description 5
- 240000007164 Salvia officinalis Species 0.000 claims description 5
- 235000013871 bee wax Nutrition 0.000 claims description 5
- 239000012166 beeswax Substances 0.000 claims description 5
- 239000012153 distilled water Substances 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 235000001050 hortel pimenta Nutrition 0.000 claims description 5
- 229920002674 hyaluronan Polymers 0.000 claims description 5
- 229960003160 hyaluronic acid Drugs 0.000 claims description 5
- 235000019388 lanolin Nutrition 0.000 claims description 5
- 229940039717 lanolin Drugs 0.000 claims description 5
- 239000011664 nicotinic acid Substances 0.000 claims description 5
- 235000020238 sunflower seed Nutrition 0.000 claims description 5
- 238000002137 ultrasound extraction Methods 0.000 claims description 5
- 229940099259 vaseline Drugs 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 5
- 241000213006 Angelica dahurica Species 0.000 claims description 4
- 241001061264 Astragalus Species 0.000 claims description 4
- 241001313857 Bletilla striata Species 0.000 claims description 4
- 235000005412 red sage Nutrition 0.000 claims description 4
- 210000004233 talus Anatomy 0.000 claims description 4
- 240000002900 Arthrospira platensis Species 0.000 claims description 3
- 235000016425 Arthrospira platensis Nutrition 0.000 claims description 3
- 239000010231 banlangen Substances 0.000 claims description 3
- 238000004587 chromatography analysis Methods 0.000 claims description 3
- 238000004440 column chromatography Methods 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 3
- 238000006911 enzymatic reaction Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000002844 melting Methods 0.000 claims description 3
- 230000008018 melting Effects 0.000 claims description 3
- WHQSYGRFZMUQGQ-UHFFFAOYSA-N n,n-dimethylformamide;hydrate Chemical compound O.CN(C)C=O WHQSYGRFZMUQGQ-UHFFFAOYSA-N 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims description 3
- 238000007670 refining Methods 0.000 claims description 3
- 239000011347 resin Substances 0.000 claims description 3
- 229920005989 resin Polymers 0.000 claims description 3
- 238000005185 salting out Methods 0.000 claims description 3
- 229940082787 spirulina Drugs 0.000 claims description 3
- 229940126680 traditional chinese medicines Drugs 0.000 claims description 3
- 244000020518 Carthamus tinctorius Species 0.000 claims description 2
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 2
- 241000196324 Embryophyta Species 0.000 claims description 2
- 108091005804 Peptidases Proteins 0.000 claims description 2
- 239000004365 Protease Substances 0.000 claims description 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 2
- 102000004139 alpha-Amylases Human genes 0.000 claims description 2
- 108090000637 alpha-Amylases Proteins 0.000 claims description 2
- 229940024171 alpha-amylase Drugs 0.000 claims description 2
- 238000001704 evaporation Methods 0.000 claims description 2
- 230000007062 hydrolysis Effects 0.000 claims description 2
- 238000006460 hydrolysis reaction Methods 0.000 claims description 2
- 241000205585 Aquilegia canadensis Species 0.000 claims 1
- 239000004909 Moisturizer Substances 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 31
- 239000000126 substance Substances 0.000 abstract description 16
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract description 15
- 241000510091 Quadrula quadrula Species 0.000 abstract description 10
- 239000010931 gold Substances 0.000 abstract description 10
- 229910052737 gold Inorganic materials 0.000 abstract description 10
- 238000004040 coloring Methods 0.000 abstract description 6
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- 230000007547 defect Effects 0.000 abstract description 3
- 238000012937 correction Methods 0.000 abstract description 2
- 238000005336 cracking Methods 0.000 abstract description 2
- 238000005562 fading Methods 0.000 abstract description 2
- 238000000465 moulding Methods 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 29
- 240000000950 Hippophae rhamnoides Species 0.000 description 20
- 239000008186 active pharmaceutical agent Substances 0.000 description 15
- 239000008280 blood Substances 0.000 description 13
- 210000004369 blood Anatomy 0.000 description 13
- 230000001737 promoting effect Effects 0.000 description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
- 238000011156 evaluation Methods 0.000 description 7
- 210000004185 liver Anatomy 0.000 description 7
- 206010028980 Neoplasm Diseases 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 230000000144 pharmacologic effect Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 5
- 229930003935 flavonoid Natural products 0.000 description 5
- 235000017173 flavonoids Nutrition 0.000 description 5
- 150000004676 glycans Chemical class 0.000 description 5
- 230000036039 immunity Effects 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 206010002198 Anaphylactic reaction Diseases 0.000 description 4
- 108010059892 Cellulase Proteins 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 4
- 241001570521 Lonicera periclymenum Species 0.000 description 4
- AIGAZQPHXLWMOJ-UHFFFAOYSA-N Tanshinone I Chemical compound C1=CC2=C(C)C=CC=C2C(C(=O)C2=O)=C1C1=C2C(C)=CO1 AIGAZQPHXLWMOJ-UHFFFAOYSA-N 0.000 description 4
- 208000003455 anaphylaxis Diseases 0.000 description 4
- 229940106157 cellulase Drugs 0.000 description 4
- 150000002215 flavonoids Chemical class 0.000 description 4
- 230000004054 inflammatory process Effects 0.000 description 4
- 206010039424 Salivary hypersecretion Diseases 0.000 description 3
- 229930013930 alkaloid Natural products 0.000 description 3
- 150000003797 alkaloid derivatives Chemical class 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000000259 anti-tumor effect Effects 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 238000007254 oxidation reaction Methods 0.000 description 3
- 208000026451 salivation Diseases 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 230000007480 spreading Effects 0.000 description 3
- 238000003892 spreading Methods 0.000 description 3
- DOUMFZQKYFQNTF-WUTVXBCWSA-N (R)-rosmarinic acid Chemical compound C([C@H](C(=O)O)OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-WUTVXBCWSA-N 0.000 description 2
- OIWSIWZBQPTDKI-UHFFFAOYSA-N 1-butyl-3-methyl-2h-imidazole;hydrobromide Chemical compound [Br-].CCCC[NH+]1CN(C)C=C1 OIWSIWZBQPTDKI-UHFFFAOYSA-N 0.000 description 2
- 241000208173 Apiaceae Species 0.000 description 2
- 101000878595 Arabidopsis thaliana Squalene synthase 1 Proteins 0.000 description 2
- 241000045403 Astragalus propinquus Species 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 241000207923 Lamiaceae Species 0.000 description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 description 2
- 241001106477 Paeoniaceae Species 0.000 description 2
- 229930183118 Tanshinone Natural products 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- 208000030961 allergic reaction Diseases 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 150000002338 glycosides Chemical class 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 229930003658 monoterpene Natural products 0.000 description 2
- 150000002773 monoterpene derivatives Chemical class 0.000 description 2
- 235000002577 monoterpenes Nutrition 0.000 description 2
- 210000000653 nervous system Anatomy 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 235000005985 organic acids Nutrition 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- -1 phenolic acid compounds Chemical class 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000013112 stability test Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 150000003648 triterpenes Chemical class 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 description 1
- GOLORTLGFDVFDW-UHFFFAOYSA-N 3-(1h-benzimidazol-2-yl)-7-(diethylamino)chromen-2-one Chemical compound C1=CC=C2NC(C3=CC4=CC=C(C=C4OC3=O)N(CC)CC)=NC2=C1 GOLORTLGFDVFDW-UHFFFAOYSA-N 0.000 description 1
- QQUHMASGPODSIW-UHFFFAOYSA-N Albiflorin Natural products C=1C=CC=CC=1C(=O)OCC12C(=O)OC3(C)CC(O)C1CC32OC1OC(CO)C(O)C(O)C1O QQUHMASGPODSIW-UHFFFAOYSA-N 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 201000009487 Amblyopia Diseases 0.000 description 1
- 241000382455 Angelica sinensis Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 241000208671 Campanulaceae Species 0.000 description 1
- 241000208828 Caprifoliaceae Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010007572 Cardiac hypertrophy Diseases 0.000 description 1
- 208000006029 Cardiomegaly Diseases 0.000 description 1
- 241000007126 Codonopsis pilosula Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- GVKKJJOMQCNPGB-JTQLQIEISA-N Cryptotanshinone Chemical compound O=C1C(=O)C2=C3CCCC(C)(C)C3=CC=C2C2=C1[C@@H](C)CO2 GVKKJJOMQCNPGB-JTQLQIEISA-N 0.000 description 1
- GVKKJJOMQCNPGB-UHFFFAOYSA-N Cryptotanshinone Natural products O=C1C(=O)C2=C3CCCC(C)(C)C3=CC=C2C2=C1C(C)CO2 GVKKJJOMQCNPGB-UHFFFAOYSA-N 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 235000002723 Dioscorea alata Nutrition 0.000 description 1
- 235000007056 Dioscorea composita Nutrition 0.000 description 1
- 235000009723 Dioscorea convolvulacea Nutrition 0.000 description 1
- 235000005362 Dioscorea floribunda Nutrition 0.000 description 1
- 235000004868 Dioscorea macrostachya Nutrition 0.000 description 1
- 235000005361 Dioscorea nummularia Nutrition 0.000 description 1
- 235000005360 Dioscorea spiculiflora Nutrition 0.000 description 1
- 244000281702 Dioscorea villosa Species 0.000 description 1
- 241000234272 Dioscoreaceae Species 0.000 description 1
- 241000220485 Fabaceae Species 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 235000006350 Ipomoea batatas var. batatas Nutrition 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 244000167230 Lonicera japonica Species 0.000 description 1
- 235000017617 Lonicera japonica Nutrition 0.000 description 1
- NFLGAXVYCFJBMK-UHFFFAOYSA-N Menthone Chemical compound CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 description 1
- 206010027439 Metal poisoning Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- YKRGDOXKVOZESV-WRJNSLSBSA-N Paeoniflorin Chemical compound C([C@]12[C@H]3O[C@]4(O)C[C@](O3)([C@]1(C[C@@H]42)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C)OC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-WRJNSLSBSA-N 0.000 description 1
- 241001474977 Palla Species 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 235000014676 Phragmites communis Nutrition 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 235000013647 Prunus pensylvanica Nutrition 0.000 description 1
- 240000007942 Prunus pensylvanica Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 244000042430 Rhodiola rosea Species 0.000 description 1
- 235000003713 Rhodiola rosea Nutrition 0.000 description 1
- ZZAFFYPNLYCDEP-HNNXBMFYSA-N Rosmarinsaeure Natural products OC(=O)[C@H](Cc1cccc(O)c1O)OC(=O)C=Cc2ccc(O)c(O)c2 ZZAFFYPNLYCDEP-HNNXBMFYSA-N 0.000 description 1
- 235000017276 Salvia Nutrition 0.000 description 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 description 1
- YMGFTDKNIWPMGF-QHCPKHFHSA-N Salvianolic acid A Natural products OC(=O)[C@H](Cc1ccc(O)c(O)c1)OC(=O)C=Cc2ccc(O)c(O)c2C=Cc3ccc(O)c(O)c3 YMGFTDKNIWPMGF-QHCPKHFHSA-N 0.000 description 1
- YMGFTDKNIWPMGF-UCPJVGPRSA-N Salvianolic acid A Chemical compound C([C@H](C(=O)O)OC(=O)\C=C\C=1C(=C(O)C(O)=CC=1)\C=C\C=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 YMGFTDKNIWPMGF-UCPJVGPRSA-N 0.000 description 1
- 206010039710 Scleroderma Diseases 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 241000287219 Serinus canaria Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000004350 Strabismus Diseases 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- QQUHMASGPODSIW-ICECTASOSA-N albiflorin Chemical compound O([C@@]12C[C@H]3[C@H](O)C[C@@]1(OC(=O)[C@]32COC(=O)C=1C=CC=CC=1)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O QQUHMASGPODSIW-ICECTASOSA-N 0.000 description 1
- 150000001345 alkine derivatives Chemical class 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001430 anti-depressive effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 239000000935 antidepressant agent Substances 0.000 description 1
- 229940005513 antidepressants Drugs 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 229940107666 astragalus root Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 235000004879 dioscorea Nutrition 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000009982 effect on human Effects 0.000 description 1
- 210000000750 endocrine system Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000010501 heavy metal poisoning Diseases 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 208000031424 hyperprolactinemia Diseases 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 229930182489 iridoid glycoside Natural products 0.000 description 1
- 150000008145 iridoid glycosides Chemical class 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 239000007934 lip balm Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 229930007503 menthone Natural products 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 206010030983 oral lichen planus Diseases 0.000 description 1
- 230000008621 organismal health Effects 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- YKRGDOXKVOZESV-UHFFFAOYSA-N paeoniflorin Natural products O1C(C)(C2(CC34)OC5C(C(O)C(O)C(CO)O5)O)CC3(O)OC1C24COC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-UHFFFAOYSA-N 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 239000001054 red pigment Substances 0.000 description 1
- 244000132619 red sage Species 0.000 description 1
- DOUMFZQKYFQNTF-MRXNPFEDSA-N rosemarinic acid Natural products C([C@H](C(=O)O)OC(=O)C=CC=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-MRXNPFEDSA-N 0.000 description 1
- TVHVQJFBWRLYOD-UHFFFAOYSA-N rosmarinic acid Natural products OC(=O)C(Cc1ccc(O)c(O)c1)OC(=Cc2ccc(O)c(O)c2)C=O TVHVQJFBWRLYOD-UHFFFAOYSA-N 0.000 description 1
- 229930183842 salvianolic acid Natural products 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 150000005856 steroid saponins Chemical class 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 229930189533 tanshinol Natural products 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 229930182493 triterpene saponin Natural products 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
- A61Q1/06—Lipsticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/001—Preparations for care of the lips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to an edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, a preparation method and application thereof. The edible traditional Chinese medicine lipstick comprises the following components: mixing the above materials, and extracting with Chinese medicinal composition (radix astragali, radix Angelicae sinensis, saviae Miltiorrhizae radix, rhizoma Dioscoreae, flos Lonicerae, bulbus Lilii, radix Codonopsis, radix Paeoniae alba, herba Menthae, and radix Angelicae Dahuricae); the traditional Chinese medicine color matching component comprises the following components: little aroma (carthamin: monascus: seabuckthorn yellow = 2:1:1); maple leaf red (carthamin: monascus pigment: seabuckthorn yellow pigment: indigo pigment = 2:1:1:2); dai Yu powder (red flower pigment: sea buckthorn yellow pigment: indigo pigment: gardenia yellow pigment=3:1:1:3); flame blue gold: (seabuckthorn yellow pigment: gardenia yellow pigment: indigo pigment: phycocyanin = 3:1:3:3); the defect of coloring chemical toner for industrial lipstick is overcome, the environment is protected, and no toxic or side effect is caused; has good correction effect on the color fading of lips, the cracking of lips and the molding of lips.
Description
Technical Field
The invention relates to the technical field of beauty cosmetics, in particular to an edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, a preparation method and application.
Background
Lipstick is a cosmetic applied to lips and imparting color tone to the lips, and can emphasize or change the contours of the lips, so that the lips are as vivid as possible, and is one of important color cosmetics. In ancient China, the lipstick is called lip balm, and the traditional Chinese medicine is mainly used as raw materials, so that the lipstick has a certain moistening effect while providing the color and the taste.
The lipstick on the market at present mostly contains chemical raw materials, and although the lipstick has a mature preparation process, the chemical components are harmful to human bodies, and once the lipstick is used carelessly, the lipstick is harmful to the health, and the mucous membrane of the lips is damaged, cracked, allergic, heavy metal poisoning and the like, and even the health of the human bodies is damaged. Therefore, the concept aims to invent the pure traditional Chinese medicine edible lipstick, which has the effects of moistening and promoting the blood circulation of local lip skin and accelerating the growth of local skin while being safe, free from toxic and side effects and not damaging the health of organisms.
Disclosure of Invention
Aiming at the technical problems, the invention aims to provide an edible traditional Chinese medicine effective extract containing traditional Chinese medicine color matching components and lipstick prepared by the edible traditional Chinese medicine effective extract, which are free from the defect of coloring chemical toner for industrial lipstick, and adopt various traditional Chinese medicines with homology of medicine and food, so that the lipstick is environment-friendly and green and has no toxic or side effect on human bodies.
The technical aim of the invention is realized by the following technical scheme:
in a first aspect, the present invention provides an edible traditional Chinese medicine lipstick composition containing traditional Chinese medicine color matching components, which is characterized in that the edible traditional Chinese medicine lipstick composition comprises traditional Chinese medicine color matching components, traditional Chinese medicine compound, matrix, lubricant, humectant, flavoring agent and traditional Chinese medicine bletilla hyacinthine gum; the Chinese medicinal color-mixing component is one or more selected from safflower pigment, monascus pigment, sea buckthorn yellow pigment, indigo pigment, gardenia yellow pigment and phycocyanin; the Chinese medicinal compound comprises one or more of radix astragali, radix Angelicae sinensis, saviae Miltiorrhizae radix, rhizoma Dioscoreae, flos Lonicerae, bulbus Lilii, radix Codonopsis, radix Paeoniae alba, herba Menthae, and radix Angelicae Dahuricae.
Wherein, astragalus root: the dried root of Astragalus mongholicus bge or Astragalus membranaceus bge of Leguminosae has effects of invigorating qi, invigorating yang, consolidating superficial resistance, suppressing sweating, inducing diuresis, relieving edema, promoting salivation, nourishing blood, removing stagnation, relieving arthralgia, removing toxic substances, expelling pus, healing sore, and promoting granulation. Contains flavonoid, saponins, polysaccharides and other chemical components, and has various pharmacological effects of resisting oxidation, regulating immunity, protecting cardiovascular and nervous system, resisting tumor, protecting liver, lowering blood sugar, resisting aging and the like.
Chinese angelica root: the product is dry root of Angelica sinensis (oliv.) Diels of Umbelliferae, and has effects of replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. The chemical components mainly comprise volatile oil, polysaccharides, organic acids, amino acids, flavonoids and the like, and have the pharmacological effects of resisting inflammation, promoting hematopoiesis, resisting tumor, protecting liver and kidney, enhancing immunity, regulating cardiovascular and cerebrovascular, and relieving uterine smooth muscle and asthma.
Root of red-rooted salvia: the product is dried root and rhizome of Salvia Miltiorrhiza bge of Labiatae, and has effects of promoting blood circulation, removing blood stasis, dredging channels, relieving pain, clearing heart fire, relieving vexation, cooling blood, and resolving carbuncle. The chemical components mainly comprise tanshinone and phenolic acid compounds, such as tanshinone, cryptotanshinone, rosmarinic acid, tanshinol, salvianolic acid, etc. Mainly has the pharmacological effects of protecting viscera, resisting fibrosis, resisting bacteria and inflammation, resisting tumor, regulating immunity, etc.
Chinese yam: the product is dried rhizome of Dioscorea opposita Thunb of Dioscoreaceae, and has effects of invigorating spleen, nourishing stomach, promoting salivation, nourishing lung, invigorating kidney, and astringing essence. The chemical components mainly comprise polysaccharide, amino acid, fatty acid, yam compounds, allantoin, trace elements, starch and the like; has pharmacological effects of reducing blood sugar, reducing blood lipid, resisting oxidation, regulating spleen and stomach, resisting tumor, and regulating immunity.
Honeysuckle flower: the product is dried flower bud or flower with primary opening of Lonicera japonica of Caprifoliaceae, and has effects of clearing heat, detoxicating, dispelling wind and heat. The chemical components mainly comprise organic acids, flavonoids, iridoid glycosides, triterpene saponins, volatile oils and the like, and have the effects of resisting inflammation, relieving fever, resisting tumor, resisting bacteria and viruses, resisting aging and oxidization, reducing blood sugar, protecting liver, protecting lung, protecting nerves, enhancing the immune function of an organism, resisting platelet aggregation and the like.
Lily: the product is dry fleshy scaly leaf of Liliaceae plant such as Plumbum Preparatium, bulbus Lilii or Bulbus Lilii with thin leaf. Has effects of nourishing yin, moistening lung, clearing heart fire and tranquilizing. Mainly contains steroid saponin, alkaloid, polysaccharide, phenols and other effective components. Has antibacterial, lung moistening, cough relieving, sedative, hypnotic, immunity regulating, antioxidant, antidepressant, antiinflammatory, antitumor, and blood sugar lowering effects.
Radix codonopsis pilosulae: the product is dry root of radix Codonopsis, or radix Codonopsis Lanceolatae of Campanulaceae, and has effects of invigorating spleen, benefiting lung, nourishing blood and promoting salivation. Mainly contains chemical components such as alkaloid, alkyne, terpenoid, flavonoid, saccharide, etc., and has pharmacological effects on nervous system, endocrine system, immune system, digestive system, etc.
White peony root: the product is dry root of Paeonia lactiflora Pallas of Ranunculaceae, and has effects of nourishing blood, regulating menstruation, astringing yin, suppressing sweating, softening liver, relieving pain, and suppressing liver yang. The chemical components mainly comprise volatile oils, monoterpenes, triterpenes, flavonoid compounds and the like, and the monoterpenes and the glycoside components thereof represented by paeoniflorin and albiflorin are recognized medicinal effect substances in white paeony root. Has effects in relieving inflammation and pain, resisting depression, resisting cancer, resisting thrombi, reducing blood lipid, lowering blood sugar, protecting liver, improving cardiac hypertrophy, relieving osteoarthritis, improving strabismus amblyopia, relieving constipation, reducing toxicity, and improving efficacy, and can be used for treating oral lichen planus, scleroderma, and hyperprolactinemia.
Peppermint: the product is dry aerial part of herba Menthae of Labiatae, and has effects of dispelling pathogenic wind and heat, refreshing, relieving sore throat, promoting eruption, dispersing stagnated liver qi, and activating qi-flowing. The chemical components mainly comprise volatile components such as menthol and menthone, and nonvolatile components such as steroid, flavone and triterpene. Has antiinflammatory, antifungal, antitumor, antioxidant, and radioprotective effects.
Radix angelicae: the product is dry root of radix Angelicae Dahuricae or radix Angelicae Dahuricae of Umbelliferae. Has effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, relieving stuffy nose, eliminating dampness, stopping leukorrhagia, and relieving swelling and pus. The chemical components mainly contain coumarin, volatile oil, glycoside, alkaloid, polysaccharide, amino acid and other chemical components, and have various pharmacological effects of anti-inflammatory, analgesic, antitumor, antibacterial, whitening and the like.
Preferably, the traditional Chinese medicine compound consists of the following traditional Chinese medicines in parts by weight: 30 parts of astragalus, 3 parts of angelica, 10 parts of red sage root, 20 parts of Chinese yam, 10 parts of honeysuckle, 15 parts of lily, 30 parts of dangshen, 10 parts of white peony root, 10 parts of peppermint and 20 parts of angelica dahurica; the traditional Chinese medicine compound extract accounts for 30% +/-5% of the total weight of the edible traditional Chinese medicine lipstick composition in percentage by weight.
Preferably, the traditional Chinese medicine color matching component consists of carthamin, monascus pigment and sea buckthorn yellow pigment in a weight ratio of 2:1:1; or the traditional Chinese medicine color matching component consists of carthamin, monascus pigment, sea buckthorn yellow pigment and indigo pigment in a weight ratio of 2:1:1:2; or the traditional Chinese medicine color matching component comprises carthamin, sea buckthorn yellow pigment, indigo pigment and gardenia yellow pigment in a weight ratio of 3:1:1:3; or the traditional Chinese medicine color matching component consists of seabuckthorn yellow pigment, gardenia yellow pigment, indigo pigment and phycocyanin pigment in a weight ratio of 3:1:3:3.
Preferably, the matrix is selected from at least one of edible beeswax, refined soybean wax, refined sunflower seed wax, lanolin, vaseline, and hyaluronic acid; the lubricant comprises olive oil and/or sweet almond oil; the humectant comprises glycerin and/or jojoba gum; the flavoring agent is one or more selected from radix Angelicae Dahuricae essential oil, radix Rhodiolae essential oil, cortex Cinnamomi essential oil, lignum Santali albi essential oil, flos Magnoliae essential oil, flos Osmanthi Fragrantis essential oil, and flos Rosae Rugosae essential oil.
Preferably, the matrix consists of edible beeswax, refined soybean wax, refined sunflower seed wax, lanolin, vaseline and hyaluronic acid in a weight ratio of 3:2:1:1:1:1; the lubricant consists of olive oil and sweet almond oil in a weight ratio of 3:1; the humectant consists of glycerin and jojoba gum in a weight ratio of 2:3.
Preferably, the weight ratio of the traditional Chinese medicine color matching components to the traditional Chinese medicine compound extract to the matrix to the lubricant to the humectant to the flavoring agent to the traditional Chinese medicine bletilla striata gum is 4-10:5:9:3:5:0.4:0.8.
In a second aspect, the present invention provides the use of an edible traditional Chinese medicine lipstick composition according to the first aspect in the preparation of a lipstick.
In a third aspect, the present invention provides a method of preparing a lipstick utilizing the edible traditional Chinese medicinal lipstick composition of the first aspect described above, the method comprising the steps of:
(1) The preparation of the traditional Chinese medicine compound extract comprises the following steps: extracting the effective components of the traditional Chinese medicine compound by adopting ultrasonic-assisted ionic liquid and a semi-bionic enzymatic method;
(2) Placing the lubricant and the humectant in an oscillator, and sufficiently oscillating until the lubricant and the humectant are uniformly mixed to form a component A;
(3) Adding the traditional Chinese medicine compound extract prepared in the step (1) into the component A, and placing the component A into an oscillator again for fully oscillating and uniformly mixing to form a component B;
(4) Adding the traditional Chinese medicine color matching component and the flavoring agent into the component B, and stirring and uniformly mixing to form a component C;
(5) Adding the matrix into the component C, heating to 80 ℃ for melting, and fully stirring by an oscillator until the materials are uniformly dissolved to form a component D;
(6) Adding purified water in an amount equal to the amount of the common bletilla tuber gum, stirring thoroughly to a viscous state, adding into the component D, and heating to a molten state to obtain a component E
(6) And (3) cooling the component E to 60 ℃, uniformly stirring, discharging, pouring into a mold, placing on a freezing platform, cooling, opening the mold, and taking out the paste to obtain the traditional Chinese medicine lipstick.
Preferably, the preparation method of the traditional Chinese medicine compound extract comprises the following steps:
firstly, mixing and crushing astragalus, angelica, red sage root, chinese yam, honeysuckle, lily, dangshen, white paeony root, peppermint and dahurian angelica root, and sieving the mixture with a 50-mesh sieve to obtain Chinese herbal compound powder; into a beaker was added 20mL of concentrated hydrochloric acid solution (ph=3.0), 1-butyl-3-methylimidazole bromide [ C ] 4 mim]BF 4 ) 10g of ionic liquid, fang Fenmo mg of traditional Chinese medicine (NH) 4 ) 2 SO 4 18g, adding cellulase with the activity of 110U/g and pectase with the activity of 150U/g, and fully stirring until the cellulase and pectase are uniformly mixed and dissolved;
regulating to simulate gastrointestinal tract pH value (pH of 0.9-7.8) according to semi-bionic extraction principle, ultrasonically centrifuging at 50deg.C for 1 hr at 500W ultrasonic power, centrifuging for 10min, transferring supernatant into another beaker, sequentially adding hydrochloric acid solution with pH=3.0, 5.0 and 5.8 into the precipitate, adding ionic liquid and (NH) in equal amount after adding acid water each time 4 ) 2 SO 4 Repeating the above steps, mixing the 3 times of extractive solutions, concentrating under reduced pressure to obtain extract, oven drying at 60deg.C to constant weight, pulverizing, and sieving with 300 mesh sieve.
Preferably, the preparation method of the traditional Chinese medicine color matching component comprises the following steps:
preparation of monascus pigment: pulverizing red rice, sieving with 80 mesh sieve, adding 12 times of 85% ethanol solution, extracting for 40min for 2 times, mixing the filtrates, concentrating under reduced pressure to obtain red rice pigment extract, drying to obtain solid pigment, and pulverizing to obtain red rice pigment;
preparation of carthamin: pulverizing Carthami flos, leaching with 55-65deg.C constant temperature water for 24 hr, standing the leaching solution, collecting supernatant, drying and concentrating for 1-4 hr, leaching with 50% ethanol below 80deg.C for 24 hr, centrifuging, concentrating the supernatant to obtain extract, and drying at room temperature to obtain carthamin;
preparation of phycocyanin: grinding spirulina, dissolving in 10 times of distilled water, repeatedly freezing and thawing at-20+ -2deg.C for 3 times, adding 15 times of water, ultrasonic extracting, centrifuging the extractive solution, and collecting supernatant; salting out the supernatant, separating by chromatography, separating to obtain a separating liquid, drying at normal temperature to obtain amorphous blue solid, and grinding and crushing to obtain phycocyanin;
preparation of indigo pigment: pulverizing radix Isatidis or folium Isatidis, sieving with 40 mesh sieve, adding 8 times of 70% N, N-dimethylformamide-water solution, ultrasonic extracting for 4 hr, concentrating the filtrate until no ethanol smell is present, and extracting with chloroform until chloroform layer is transparent; collecting chloroform layer, recovering under reduced pressure, oven drying at 60deg.C, weighing, and grinding to obtain indigo pigment;
preparation of sea buckthorn yellow pigment: removing branches and leaves of sea buckthorn fruits, quick-freezing, thawing by microwaves and drying; crushing the dried sea buckthorn fruits to separate skin and seeds; collecting fructus Hippophae, oven drying again, pulverizing, sieving with 80 mesh sieve, adding 12 times of acetone for ultrasonic-assisted extraction, centrifuging the extractive solution, collecting supernatant, and evaporating to recover solvent to obtain fructus Hippophae yellow pigment;
preparing gardenia yellow pigment: pulverizing fructus Gardeniae, sieving with 40 mesh sieve, adding 10 times of 60% ethanol solution, extracting for 1 hr for 2 times; mixing the extractive solutions, filtering, refining the filtrate with macroporous resin column chromatography, eluting with water, 20% ethanol and 75% ethanol sequentially to obtain gardenia yellow pigment, recovering solvent under reduced pressure, and drying to obtain gardenia yellow pigment.
Preferably, the preparation method of the traditional Chinese medicine bletilla striata gum comprises the following steps:
weighing fine powder of rhizoma bletilla which is sieved by a 60-mesh sieve, adding 12 times of distilled water for ultrasonic extraction, filtering the extracting solution, regulating the pH of the subsequent filtrate to 6.5, and adding 3 permillage w/v of medium-temperature alpha-amylase for hydrolysis; regulating pH to 7.5, adding 3.3%w/v plant protease for enzymolysis, ultrafiltering, concentrating under reduced pressure to obtain soft extract, drying, and pulverizing to obtain rhizoma bletilla gum.
The beneficial effects of the invention are as follows: the invention firstly provides an edible traditional Chinese medicine lipstick composition containing traditional Chinese medicine color matching components, and the composition is prepared into lipstick, which gets rid of the defect of chemical toner coloring for industrial lipstick, is environment-friendly and green, and has no toxic or side effect; has good correction effect on the color fading of lips, the cracking of lips and the molding of lips.
Detailed Description
The present invention will be described in further detail with reference to examples.
Example 1 preparation of edible traditional Chinese medicine lipstick containing traditional Chinese medicine color-mixing component
(1) Preparation of traditional Chinese medicine color-mixing component
Preparation of monascus pigment: pulverizing red rice, sieving with 80 mesh sieve, adding 12 times of 85% ethanol solution, extracting for 40min for 2 times, mixing the filtrates, concentrating under reduced pressure to obtain red rice pigment extract, spray drying to obtain solid pigment, and pulverizing to obtain powder red rice pigment.
Preparation of carthamin: pulverizing Carthami flos, leaching with 55-65deg.C constant temperature water for 24 hr, standing the leaching solution until insoluble granule is precipitated, homogenizing and transparent, and centrifuging (30 min,3000rpm, 2-4deg.C); collecting supernatant, drying and concentrating for 1-4 hr with rotary evaporator, maintaining with 50% ethanol at 80deg.C or below, and leaching for 24 hr, wherein the color is changed from orange red (transparent for 2-5 hr) to deep orange red (very transparent for 24 hr), and the carthamin is considered to be completely extracted. And centrifuging the extractive solution, concentrating the supernatant with rotary evaporator (45deg.C, 0.08 MP), collecting extract, and drying at room temperature to obtain carthamin.
Preparation of phycocyanin: grinding spirulina, dissolving in 10 times of distilled water, repeatedly freezing and thawing at-20+ -2deg.C for 3 times, adding 15 times of water, ultrasonic extracting (20 KHz,100w,20 min), collecting extractive solution, centrifuging (15 min,3000rpm, 4deg.C), and collecting supernatant. The supernatant was treated with (NH) 4 ) 2 SO 4 Salting out, separating by Sephadex G-100 chromatography, and collecting separating liquid, which is water solution of phycocyanin, drying by air blast at normal temperature to obtain amorphous blue solid, grinding and pulverizing to obtain phycocyanin.
Preparation of indigo pigment: pulverizing radix Isatidis or folium Isatidis, sieving with 40 mesh sieve, adding 8 times of 70% N, N-dimethylformamide-water solution, ultrasonic extracting for 4 hr, concentrating the filtrate under reduced pressure until there is no obvious ethanol smell, extracting with chloroform until the chloroform layer is transparent, collecting chloroform layer, recovering under reduced pressure, oven drying in oven at 60deg.C, weighing, grinding to obtain indigo pigment solid, and grinding to obtain indigo pigment.
Preparation of sea buckthorn yellow pigment: removing branches and leaves of fresh sea buckthorn fruits, quick-freezing, thawing sea buckthorn fruits by microwaves, and drying by hot air. Crushing the dried sea buckthorn fruits by using a tissue masher until the skin and the seeds are separated. Collecting fructus Hippophae, oven drying again, pulverizing, sieving with 80 mesh sieve, adding 12 times of acetone, performing ultrasonic-assisted extraction (20 KHz,100w,40 min), centrifuging the extractive solution, collecting supernatant, and recovering solvent by rotary evaporator to obtain fructus Hippophae yellow pigment.
Preparing gardenia yellow pigment: pulverizing fructus Gardeniae, sieving with 40 mesh sieve, adding 10 times of 60% ethanol solution, extracting for 1 hr for 2 times. Mixing the extractive solutions, filtering, refining the filtrate with HPD-100A macroporous resin column chromatography, eluting with water, 20% ethanol and 75% ethanol sequentially to obtain gardenia yellow pigment, recovering solvent under reduced pressure, and drying to obtain refined gardenia yellow pigment product.
The traditional Chinese medicine color matching component is prepared by the following steps: little aroma (carthamin: monascus: seabuckthorn yellow = 2:1:1); maple leaf red (carthamin: monascus pigment: seabuckthorn yellow pigment: indigo pigment = 2:1:1:2); dai Yu powder (red flower pigment: hippophae rhamnoides yellow: indigo pigment: gardenia yellow pigment=3:1:1:3); flame blue gold: (seabuckthorn yellow: gardenia yellow pigment: indigo pigment: phycocyanin = 3:1:3:3);
(2) Preparation of Chinese herbal compound extract
Ultrasonic-assisted ionic liquid and semi-bionic enzymatic method are adopted to extract the effective components of the traditional Chinese medicine compound:
firstly, 30g of astragalus, 3g of angelica, 10g of red sage root, 20g of Chinese yam, 10g of honeysuckle, 15g of lily, 30g of codonopsis pilosula, 10g of white peony root, 10g of peppermint and 20g of angelica are mixed and crushed, and the mixture is sieved by a 50-mesh sieve to obtain the traditional Chinese medicine compound powder.
Into a beaker was added 20mL of concentrated hydrochloric acid solution (ph=3.0), 1-butyl-3-methylimidazole bromide [ C ] 4 mim]BF 4 ) 10g of ionic liquid, fang Fenmo mg of traditional Chinese medicine (NH) 4 ) 2 SO 4 18g, adding cellulase with the activity of 110U/g and pectase with the activity of 150U/g, and fully stirring until the cellulase and pectase are uniformly mixed and dissolved. Then according to the semi-bionic extraction principle, different acidolysis is added for adjustmentSimulating pH value of gastrointestinal tract, ultrasonic treating at ultrasonic power 500W at 50deg.C for 1 hr, centrifuging for 10min, transferring supernatant to another beaker, sequentially adding concentrated hydrochloric acid solution with pH=3.0, 5.0 and 5.8, adding ionic liquid and (NH) in the same amount after adding acid water each time 4 ) 2 SO 4 Repeating the above steps, mixing the 3 times of extractive solutions, concentrating under reduced pressure to obtain extract, oven drying at 60deg.C to constant weight, pulverizing, and sieving with 300 mesh sieve.
(3) Edible traditional Chinese medicine lipstick comprises the following components:
the weight portion of the traditional Chinese medicine compound extract is 5;
a substrate: edible beeswax, refined soybean wax, refined sunflower seed wax, lanolin and vaseline. Matrix systems such as hyaluronic acid and the like are calculated as the weight ratio of 3:2:1:1:1:1;
the traditional Chinese medicine color matching component is prepared by the following steps:
little aroma (carthamin: monascus: seabuckthorn yellow = 2:1:1);
maple leaf red (carthamin: monascus pigment: seabuckthorn yellow pigment: indigo pigment = 2:1:1:2);
dai Yu powder (red pigment: hippophae rhamnoides yellow: indigo: gardenia yellow pigment=3:1:1:3);
flame blue gold: (seabuckthorn yellow: gardenia yellow pigment: indigo pigment: phycocyanin = 3:1:3:3);
and (3) a lubricant: the weight ratio of olive oil to sweet almond oil is 3:1;
humectant: glycerin and reed canary glue are 2:3 by weight;
traditional Chinese medicine essential oil flavoring agent: is selected from radix Angelicae Dahuricae essential oil, radix Rhodiolae essential oil, cortex Cinnamomi essential oil, lignum Santali albi essential oil, flos Magnoliae essential oil, flos Osmanthi Fragrantis essential oil, and flos Rosae Rugosae essential oil; 0.4 parts by weight.
The weight portion of the traditional Chinese medicine bletilla striata gum is 0.8.
(4) Preparation method
The specific steps of each component are as follows with reference to tables 1-4:
s1: placing olive oil, sweet almond oil, glycerol and jojoba gum in an oscillator, and sufficiently oscillating until the olive oil, the sweet almond oil, the glycerol and the jojoba gum are uniformly mixed to form a component A;
s2: adding the traditional Chinese medicine compound extract into the component A, and placing the component A into an oscillator again for fully oscillating, stirring and uniformly mixing to form a component B;
s3: adding the traditional Chinese medicine color matching component and the flavoring agent into the component B, and stirring and uniformly mixing to form a component C;
s4: adding matrix into component C, heating to 80deg.C for melting, and stirring with a shaker until the materials are dissolved uniformly to form a group
D, dividing;
s5: adding purified water in an amount equal to the amount of the common bletilla tuber gum, stirring to a viscous state, adding into component D, and heating
In the molten state, component E is formed;
s6: and (3) cooling the component E to 60 ℃, uniformly stirring, discharging, pouring into a mold, placing on a freezing platform, cooling, opening the mold, and taking out the paste to obtain the traditional Chinese medicine lipstick.
Examples are lipstick products prepared according to optimal process parameters; the comparative examples are lipstick products prepared according to the optimal technological parameters, but with the traditional Chinese medicine compound components or/and the traditional Chinese medicine color matching components removed. Abbreviations in the following: little incense (XS), maple leaf red (FY), dai Yu powder (DY), flame blue gold (LY), example (SZ), control example (DS). In addition, 2 kinds of commercially available lipsticks were used as a control group, and 3 samples of each of the commercially available lipsticks were taken in parallel and were designated as commercially available control 1 (SS 1-1 to SS 1-3) and commercially available control 2 (SS 2-1 to SS 2-3), respectively. SS1 is a commercially available red cherry lipstick with a certain brand of moisturizing and repairing function; SS2 is a commercial rhodiola rosea maintenance lipstick of a certain brand.
Table 1 Small aroma (XS) lipstick and components of each comparative example and parts by weight thereof
Note that: the XS-SZ-1-3 samples described in Table 1 are small aroma (XS) lipstick samples (3 independent samples in parallel);
the XS-DS 1-XS-DS 1-3 are small-aroma (XS) lipsticks (3 parallel independent samples) without adding traditional Chinese medicine compound extracts;
XS-DS2-1 to XS-DS2-3 are small-aroma (XS) lipsticks (3 independent samples in parallel) without traditional Chinese medicine color-mixing components;
the XS-DS3-1 to XS-DS3-3 are small-aroma (XS) lipsticks (parallel 3 independent samples) without adding traditional Chinese medicine compound extracts and traditional Chinese medicine color-mixing components.
Table 2 maple leaf Red (FY) lipstick and its respective components and parts by weight of each comparative example
Note that: FY-SZ-1-3 described in Table 1 are maple leaf red (FY) lipstick samples (3 independent samples in parallel);
FY-DS 1-FY-DS 1-3 are maple leaf red (FY) lipstick without traditional Chinese medicine compound extract (3 parallel independent samples);
FY-DS2-1 to FY-DS2-3 are maple leaf red (FY) lipsticks (3 independent samples in parallel) without adding traditional Chinese medicine color mixing components;
FY-DS3-1 to FY-DS3-3 are maple leaf red (FY) lipstick (parallel 3 independent samples) without adding traditional Chinese medicine compound extract and traditional Chinese medicine color mixing component.
TABLE 3 Dai Yu Pink (DY) lipstick and its respective components and parts by weight of the respective comparative examples
Note that: DY-SZ-1-3 in Table 1 are Dai Yu Pink (DY) lipstick samples (3 independent samples in parallel);
DY-DS 1-DY-DS 1-3 are Daiyu powder (DY) lipstick (3 parallel independent samples) without adding traditional Chinese medicine compound extract;
DY-DS 2-1-DY-DS 2-3 are Daiyu powder (DY) lipstick (3 parallel independent samples) without adding traditional Chinese medicine color mixing components;
DY-DS 3-1-DY-DS 3-3 is Daiyu powder (DY) lipstick (parallel 3 independent samples) without adding traditional Chinese medicine compound extract and traditional Chinese medicine color-mixing component.
TABLE 4 flame blue gold (LY) lipstick and its respective components and parts by weight of the respective comparative examples
Note that: LY-SZ-1-3 is shown in Table 1 as a flame bluish gold (LY) lipstick sample (3 independent samples in parallel);
LY-DS 1-LY-DS 1-3 is flame blue gold (LY) lipstick without traditional Chinese medicine compound extract (parallel 3 independent samples);
LY-DS2-1 to LY-DS2-3 are flame bluish gold (LY) lipsticks (3 independent samples in parallel) without traditional Chinese medicine color matching components;
LY-DS 3-1-LY-DS 3-3 is flame blue gold (LY) lipstick (parallel 3 independent samples) without adding Chinese herbal compound extract and Chinese herbal color-mixing component.
(6) Lipstick product stability detection
Heat resistance experiment: the sample was left at 5 ℃ for 24 hours, after returning to room temperature, the appearance was not changed significantly and could be used normally, and after returning to room temperature, the appearance was changed and could not be used normally, was recorded as "+".
Cold resistance experiment: the sample was left at-10 ℃ for 24 hours, after returning to room temperature, the appearance was not changed significantly and could be used normally, and after returning to room temperature, the appearance was changed and could not be used normally, was recorded as "+".
Table 5 lipstick product stability test results
According to the stability test results of lipstick products shown in Table 5, the lipsticks disclosed by the patent have good heat-resistant stability and cold-resistant stability.
(7) Determination of the spreadability of lipstick
A certain amount of lipstick sample (0.1 g) is weighed and smeared on the bottom of a weight with the diameter of 2.6cm and the weight of 100g, the weight is placed on the upper end of a glass plate with the inclination angle of 30 degrees, the sample is spread on the glass plate under the pressure action of the weight until the bottom of the weight is completely free of lipstick, the spreading distance of the paste is measured, and the spreading performance of the sample is evaluated as the longer the distance is, the better the spreading performance is.
Table 6 results of the spreadability test of lipstick products
According to the results of the lipstick product spreadability measurement shown in Table 6, the spreadability of all lipstick products is between 34.00 and 52.33mm, while the spreadability results of the four lipstick color number (XS-SZ, FY-SZ, DY-SZ and LY-SZ) examples described in the patent are respectively 47.33mm, 52.33mm, 46.33mm and 40.66mm, and the results are obviously higher than that of the two commercially available lipstick comparative examples (SS 1:34.00mm and SS2:37.33 mm), so that the lipstick products disclosed in the patent have good spreadability.
(8) Evaluation of the overall appearance, smell, moisture and color durability of lipstick products
60 female white collar subjects with the age of 18-45 years in the same area are selected and randomly divided into 6 groups, so that 10 subjects are ensured for each independent lipstick sample. Six lipsticks of small aroma color (XS), maple leaf red (FY), dai jade powder (DY), flame blue gold (LY), commercial control 1 (SS 1) and commercial control 2 (SS 2) were tested respectively, and after 3 hours of use with lip makeup, the evaluation of the overall appearance, smell, moisturization and color retention was recorded.
Evaluation criteria: a classification of 10 is excellent; 8, the classification is good; 6 is divided into general; 4 is divided into differences; the 2-division is extremely bad. The evaluation results were recorded and the average value was counted, and the results are shown in Table 7.
Table 7 evaluation results of the overall appearance, smell, moisture, and color durability of lipstick product
| Sample of | Overall appearance | Smell of | Degree of moistening | Color permanence |
| XS | 8.6 | 7.4 | 8.8 | 8.8 |
| DY | 8.8 | 8.6 | 8.6 | 8.6 |
| FY | 8.8 | 8.8 | 9 | 8.2 |
| LY | 8.4 | 7.8 | 8.6 | 8.2 |
| SS1 | 8.6 | 8.8 | 8.2 | 7.6 |
| SS2 | 9.4 | 8.0 | 8.6 | 8.2 |
The overall appearance, smell, moistening degree and coloring durability of the lipstick products in the table 7 can be known, and the overall appearance, smell, moistening degree and coloring durability of the four lipstick products in the patent are well evaluated, so that the lipstick has strong popularization.
(9) Lip protection effect and anaphylactic reaction test of lipstick product
The test tests lip protection effect and anaphylactic reaction of the lipstick product on the basis of 60 subjects adopted in the evaluation of the overall appearance, smell, moistening degree and coloring durability of the lipstick product (8). Test procedure: the lips were cleaned every morning and the corresponding lipsticks were applied once, and before and after application, the appearance of the lips was observed, whether the lips were skinned, whether the lips were visible, and the lip color was observed. The continuous use is observed for 14 days, whether the lip is allergic or not is recorded, and a record table is collected and counted.
Evaluation criteria: lip mark repairing effect: 3 is classified as excellent, 2 is classified as good, 1 is classified as medium, and 0 is classified as poor; lip color improvement: 3 is classified as excellent, 2 is classified as good, 1 is classified as medium, and 0 is classified as poor; improvement of skinning phenomenon: the 3-score is excellent, the 2-score is good, the 1-score is medium, and the 0-score is poor.
Table 8 lip care effect and allergic reaction test of lipstick product
| Group of | Lip mark | Lip color | Skinning | Allergic reaction |
| XS | 2.1 | 2.2 | 2 | Without any means for |
| DY | 2.3 | 2.2 | 2.4 | Without any means for |
| FY | 2.1 | 2 | 2.2 | Without any means for |
| LY | 2.4 | 2.5 | 2.4 | Without any means for |
| SS1 | 2.2 | 2.1 | 2.4 | Without any means for |
| SS2 | 2.2 | 2.3 | 2.3 | Without any means for |
According to the lip protection effect and the anaphylactic reaction test result of the lipstick product shown in Table 8, the lipstick product disclosed by the patent has good moistening and repairing effects, and anaphylactic reaction cannot be generated to a user.
The lip care cosmetic can provide good lip moistening and repairing effects for people of different ages, has the functional characteristics of safety, green, health care and the like while keeping cosmetic beauty, and ensures the user to be relieved and keep healthy.
Description: the present disclosure is not intended to limit the scope of the invention, but is merely illustrative of the embodiments of the present disclosure, and the invention is not limited to the details of the technology, spirit, principle of the present disclosure, and any modification, equivalent replacement, and improvement based on the present disclosure.
Claims (10)
1. An edible traditional Chinese medicine lipstick composition containing traditional Chinese medicine color matching components is characterized by comprising traditional Chinese medicine color matching components, traditional Chinese medicine compounds, matrixes, lubricants, moisturizers, flavoring agents and traditional Chinese medicine bletilla hyacinthine gum; the Chinese medicinal color-mixing component is one or more selected from safflower pigment, monascus pigment, sea buckthorn yellow pigment, indigo pigment, gardenia yellow pigment and phycocyanin; the Chinese medicinal compound comprises one or more of radix astragali, radix Angelicae sinensis, saviae Miltiorrhizae radix, rhizoma Dioscoreae, flos Lonicerae, bulbus Lilii, radix Codonopsis, radix Paeoniae alba, herba Menthae, and radix Angelicae Dahuricae.
2. The edible traditional Chinese medicine lipstick composition according to claim 1, wherein the traditional Chinese medicine compound is composed of the following traditional Chinese medicines in parts by weight: 30 parts of astragalus, 3 parts of angelica, 10 parts of red sage root, 20 parts of Chinese yam, 10 parts of honeysuckle, 15 parts of lily, 30 parts of dangshen, 10 parts of white peony root, 10 parts of peppermint and 20 parts of angelica dahurica; the traditional Chinese medicine compound extract accounts for 30% +/-5% of the total weight of the edible traditional Chinese medicine lipstick composition in percentage by weight.
3. The edible traditional Chinese medicine lipstick composition according to claim 1, wherein the traditional Chinese medicine color matching component consists of carthamin, monascus pigment and sea buckthorn yellow pigment in a weight ratio of 2:1:1; or the traditional Chinese medicine color matching component consists of carthamin, monascus pigment, sea buckthorn yellow pigment and indigo pigment in a weight ratio of 2:1:1:2; or the traditional Chinese medicine color matching component comprises carthamin, sea buckthorn yellow pigment, indigo pigment and gardenia yellow pigment in a weight ratio of 3:1:1:3; or the traditional Chinese medicine color matching component consists of seabuckthorn yellow pigment, gardenia yellow pigment, indigo pigment and phycocyanin pigment in a weight ratio of 3:1:3:3.
4. The edible traditional Chinese medicine lipstick composition according to claim 1, wherein the matrix is at least one selected from edible beeswax, refined soybean wax, refined sunflower seed wax, lanolin, vaseline, and hyaluronic acid; the lubricant comprises olive oil and/or sweet almond oil; the humectant comprises glycerin and/or jojoba gum; the flavoring agent is one or more selected from radix Angelicae Dahuricae essential oil, radix Rhodiolae essential oil, cortex Cinnamomi essential oil, lignum Santali albi essential oil, flos Magnoliae essential oil, flos Osmanthi Fragrantis essential oil, and flos Rosae Rugosae essential oil.
5. The edible traditional Chinese medicine lipstick composition according to claim 4, wherein the matrix is composed of edible beeswax, refined soybean wax, refined sunflower seed wax, lanolin, vaseline and hyaluronic acid in a weight ratio of 3:2:1:1:1:1; the lubricant consists of olive oil and sweet almond oil in a weight ratio of 3:1; the humectant consists of glycerin and jojoba gum in a weight ratio of 2:3.
6. The edible traditional Chinese medicine lipstick composition according to claim 5, wherein the weight ratio of the traditional Chinese medicine color matching component, the traditional Chinese medicine compound extract, the matrix, the lubricant, the humectant, the flavoring agent and the traditional Chinese medicine bletilla striata gum is 4-10:5:9:3:5:0.4:0.8.
7. Use of an edible traditional Chinese medicine lipstick composition according to any one of claims 1-6 for preparing a lipstick.
8. The method of preparing lipstick from an edible traditional Chinese medicine lipstick composition according to claim 7, comprising the steps of:
(1) The preparation of the traditional Chinese medicine compound extract comprises the following steps: extracting the effective components of the traditional Chinese medicine compound by adopting ultrasonic-assisted ionic liquid and a semi-bionic enzymatic method;
(2) Placing the lubricant and the humectant in an oscillator, and sufficiently oscillating until the lubricant and the humectant are uniformly mixed to form a component A;
(3) Adding the traditional Chinese medicine compound extract prepared in the step (1) into the component A, and placing the component A into an oscillator again for fully oscillating and uniformly mixing to form a component B;
(4) Adding the traditional Chinese medicine color matching component and the flavoring agent into the component B, and stirring and uniformly mixing to form a component C;
(5) Adding the matrix into the component C, heating to 80 ℃ for melting, and fully stirring by an oscillator until the materials are uniformly dissolved to form a component D;
(6) Adding purified water in an amount equal to the amount of the common bletilla tuber gum, stirring thoroughly to a viscous state, adding into the component D, and heating to a molten state to obtain a component E
(6) And (3) cooling the component E to 60 ℃, uniformly stirring, discharging, pouring into a mold, placing on a freezing platform, cooling, opening the mold, and taking out the paste to obtain the traditional Chinese medicine lipstick.
9. The method of claim 8, wherein the method of preparing the traditional Chinese medicine toning component comprises the steps of:
preparation of monascus pigment: pulverizing red rice, sieving with 80 mesh sieve, adding 12 times of 85% ethanol solution, extracting for 40min for 2 times, mixing the filtrates, concentrating under reduced pressure to obtain red rice pigment extract, drying to obtain solid pigment, and pulverizing to obtain red rice pigment;
preparation of carthamin: pulverizing Carthami flos, leaching with 55-65deg.C constant temperature water for 24 hr, standing the leaching solution, collecting supernatant, drying and concentrating for 1-4 hr, leaching with 50% ethanol below 80deg.C for 24 hr, centrifuging, concentrating the supernatant to obtain extract, and drying at room temperature to obtain carthamin;
preparation of phycocyanin: grinding spirulina, dissolving in 10 times of distilled water, repeatedly freezing and thawing at-20+ -2deg.C for 3 times, adding 15 times of water, ultrasonic extracting, centrifuging the extractive solution, and collecting supernatant; salting out the supernatant, separating by chromatography, separating to obtain a separating liquid, drying at normal temperature to obtain amorphous blue solid, and grinding and crushing to obtain phycocyanin;
preparation of indigo pigment: pulverizing radix Isatidis or folium Isatidis, sieving with 40 mesh sieve, adding 8 times of 70% N, N-dimethylformamide-water solution, ultrasonic extracting for 4 hr, concentrating the filtrate until no ethanol smell is present, and extracting with chloroform until chloroform layer is transparent; collecting chloroform layer, recovering under reduced pressure, oven drying at 60deg.C, weighing, and grinding to obtain indigo pigment;
preparation of sea buckthorn yellow pigment: removing branches and leaves of sea buckthorn fruits, quick-freezing, thawing by microwaves and drying; crushing the dried sea buckthorn fruits to separate skin and seeds; collecting fructus Hippophae, oven drying again, pulverizing, sieving with 80 mesh sieve, adding 12 times of acetone for ultrasonic-assisted extraction, centrifuging the extractive solution, collecting supernatant, and evaporating to recover solvent to obtain fructus Hippophae yellow pigment;
preparing gardenia yellow pigment: pulverizing fructus Gardeniae, sieving with 40 mesh sieve, adding 10 times of 60% ethanol solution, extracting for 1 hr for 2 times; mixing the extractive solutions, filtering, refining the filtrate with macroporous resin column chromatography, eluting with water, 20% ethanol and 75% ethanol sequentially to obtain gardenia yellow pigment, recovering solvent under reduced pressure, and drying to obtain gardenia yellow pigment.
10. The method of claim 8, wherein the preparation method of the traditional Chinese medicine bletilla hyacinthine gum comprises the following steps: weighing fine powder of rhizoma bletilla which is sieved by a 60-mesh sieve, adding 12 times of distilled water for ultrasonic extraction, filtering the extracting solution, regulating the pH of the subsequent filtrate to 6.5, and adding 3 permillage w/v of medium-temperature alpha-amylase for hydrolysis; regulating pH to 7.5, adding 3.3%w/v plant protease for enzymolysis, ultrafiltering, concentrating under reduced pressure to obtain soft extract, drying, and pulverizing to obtain rhizoma bletilla gum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211098665.1A CN116035964A (en) | 2022-09-07 | 2022-09-07 | Edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211098665.1A CN116035964A (en) | 2022-09-07 | 2022-09-07 | Edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116035964A true CN116035964A (en) | 2023-05-02 |
Family
ID=86116937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211098665.1A Pending CN116035964A (en) | 2022-09-07 | 2022-09-07 | Edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116035964A (en) |
-
2022
- 2022-09-07 CN CN202211098665.1A patent/CN116035964A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104758222A (en) | Beauty product with effects of repair and regeneration, moisturizing and senility delaying | |
| CN105535448A (en) | Traditional Chinese medicine composition for treating child myasthenia gravis | |
| CN105918946B (en) | Jujube-wolfberry liver-nourishing composition, granules and preparation method thereof | |
| Mohajeri et al. | Available saffron formulations and product patents | |
| CN101361911A (en) | External skin composition with wrinkle-dispelling function and production method thereof | |
| CN107296935B (en) | Traditional Chinese medicine composition and traditional Chinese medicine preparation for treating peripheral facial paralysis | |
| CN112754972A (en) | Traditional Chinese medicine hair-blacking composition and preparation thereof | |
| CN116035964A (en) | Edible traditional Chinese medicine lipstick effective extract containing traditional Chinese medicine color matching components, preparation method and application | |
| CN104324310A (en) | Traditional Chinese medicine composition for treating mycotic keratitis after immune suppression and preparation method thereof | |
| CN104189234A (en) | Traditional Chinese medicine preparation for treating metrorrhagia and metrostaxis | |
| CN107952036B (en) | Traditional Chinese medicine preparation for reducing blood sugar and preparation method thereof | |
| CN1060379C (en) | Chines medicine for treating vitiligo and preparation method thereof | |
| CN105561098A (en) | Medicine for treating erosive beriberi | |
| CN108704040B (en) | Traditional Chinese medicine composition and application thereof | |
| CN111700948A (en) | External traditional Chinese medicine for preventing and treating new coronary pneumonia and preparation method thereof | |
| CN1085439A (en) | A kind of anticancer herbal drug | |
| CN1785245A (en) | Method for preparing composite traditional Chinese medicine soft capsule | |
| CN114344434B (en) | Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof | |
| CN115025175B (en) | Throat-clearing and-moistening lozenge as well as preparation method and application thereof | |
| CN107661391A (en) | Treat Yao nationality medicine external preparation of the proliferation of mammary gland and preparation method thereof | |
| CN112426510B (en) | Composition for treating arthritis and preparation method thereof | |
| CN106139105A (en) | One treats uremic Chinese medicine formula | |
| CN108714167B (en) | A Chinese medicinal preparation for external use for treating vitiligo, and its preparation method | |
| CN106924517A (en) | A kind of Chinese medicine preparation for treating closo acne and preparation method thereof | |
| CN116870111A (en) | Traditional Chinese medicine composition for treating peripheral facial paralysis and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |