CN107296935B

CN107296935B - Traditional Chinese medicine composition and traditional Chinese medicine preparation for treating peripheral facial paralysis

Info

Publication number: CN107296935B
Application number: CN201710646430.4A
Authority: CN
Inventors: 刘建浩; 王天磊; 黄文灵; 张雪晶; 曹红; 樊伟; 褚江海; 徐琼; 谭春凤; 黄建福; 凌绵聪
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-08-01
Filing date: 2017-08-01
Publication date: 2020-05-19
Anticipated expiration: 2037-08-01
Also published as: CN107296935A

Abstract

The invention discloses a traditional Chinese medicine composition for treating peripheral facial paralysis, which is prepared from the following raw materials: radix astragali, rhizoma Atractylodis Macrocephalae, radix Codonopsis, rhizoma Chuanxiong, Scorpio, periostracum Cicadae, rhizoma Typhonii, Bombyx Batryticatus, herba Ephedrae, herba asari, herba Schizonepetae, radix Saposhnikoviae, concretio silicea Bambusae, radix Angelicae sinensis, caulis Spatholobi, radix Puerariae, rhizoma Gastrodiae, ramulus Uncariae cum uncis, herba Erodii seu Geranii, fructus Aurantii, radix Glycyrrhizae, rhizoma Et radix Notopterygii, herba Menthae, radix Paeoniae alba, radix bupleuri, radix Curcumae, rhizoma Cyperi, semen Persicae, and flos Carthami; the preparation method of the pill comprises the steps of decocting, extracting, concentrating into thick paste, preparing into pills and the like. The invention also discloses a traditional Chinese medicine preparation for treating peripheral facial paralysis, which applies the traditional Chinese medicine composition for treating peripheral facial paralysis and a pharmaceutically acceptable carrier. The traditional Chinese medicine composition and the traditional Chinese medicine preparation for treating peripheral facial paralysis can be used for treating peripheral facial paralysis in a targeted manner, and are remarkable in effect, safe and reliable.

Description

Traditional Chinese medicine composition and traditional Chinese medicine preparation for treating peripheral facial paralysis

Technical Field

The application relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating peripheral facial paralysis and a preparation method thereof.

Background

Peripheral facial paralysis (called facial paralysis for short) was first reported by a neurologist Dr. Charles Bell in England 150 years ago, and clinically, Bell described facial paralysis is the most common idiopathic peripheral facial paralysis in clinic, commonly called Bell facial paralysis or paralysis, and is peripheral facial paralysis caused by acute non-suppurative inflammation of the facial nerve tract. In fact the scope of peripheral facial paralysis is not limited to Bell's facial paralysis.

The mechanism of this disease is not well understood at present, and it is generally considered to be non-suppurative facial neuritis. Because of 2 possibilities: i.e. the facial nerve itself or its peripheral lesions. The facial nerve is considered to be caused by vasospasm of local trophic nerve caused by wind cold, so that nerve ischemia, edema and compression are caused, and also considered to be caused by rheumatic or viral infection, for example, facial paralysis caused by herpes virus invading the facial nerve is called Hunt facial paralysis; peripheral factors include facial nerve compression or blood circulation disorder caused by periostitis in the foramen magnum, and facial nerve paralysis. The early pathological changes of the facial paralysis are mainly edema and demyelination of the facial nerve, and axonal degeneration, atrophy and the like can occur at the later stage. The stage of facial neuritis lesion is not uniformly divided at present, but according to clinical manifestations and general conditions of recovery from damaged nerves, 1-2 weeks after the lesion is called acute stage (or early stage), 2-6 months after the lesion is called recovery stage (middle stage), and more than half a year is called sequela stage (late stage).

The disease belongs to the categories of 'facial paralysis', 'sudden mouth crack' and the like in the traditional Chinese medicine, and is considered to be caused by overstrain, insufficient healthy qi of an organism, empty and deficient veins, insecurity of defensive exterior, and wind cold or wind heat entering middle-face meridians and collaterals due to deficiency, so that qi and blood obstruction, channel and tendon dysfunction, tendon and muscle restriction and facial paralysis occur. Peripheral facial paralysis includes symptoms of muscles and muscles of eyes and cheeks, and the inability of the eyelids to close is caused by dysfunction of the muscles of the foot-sun and the foot-sun meridian as the muscles of the foot-sun meridian are the "supraorbital" and the muscles of the foot-sun meridian are the "infraorbital"; the mouth and cheek are mainly caused by the taiyang of hand and yangming meridians of hand and foot, and the facial distortion is mainly caused by dysfunction of these three meridians.

At present, a plurality of traditional Chinese medicines for treating peripheral facial paralysis have different efficacies, but have poor pertinence.

Disclosure of Invention

The invention provides a traditional Chinese medicine composition and a traditional Chinese medicine preparation for treating peripheral facial paralysis.

In order to achieve the purpose, the technical scheme of the invention is as follows:

the traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials in parts by weight:

20-50 parts of astragalus root, 5-15 parts of white atractylodes rhizome, 5-15 parts of codonopsis pilosula, 10-20 parts of ligusticum wallichii, 1-10 parts of scorpion, 7-15 parts of cicada slough, 5-15 parts of rhizoma typhonii, 5-15 parts of stiff silkworm, 3-7 parts of ephedra herb, 1-5 parts of asarum, 10-20 parts of schizonepeta, 10-20 parts of divaricate saposhnikovia root, 10-20 parts of tabasheer, 10-30 parts of angelica and 20-50 parts of suberect spatholobus stem, 20-30 parts of kudzuvine root, 10-20 parts of tall gastrodia tuber, 10-30 parts of uncaria, 20-50 parts of geranium, 10-30 parts of bitter orange, 7-15 parts of liquoric root, 5-15 parts of incised notopterygium rhizome, 5-15 parts of mint, 5-15 parts of white paeony root, 10-20 parts of Chinese thorowax root, 7-15 parts of turmeric root-tuber, 7-15 parts of nutgrass galingale rhizome, 5-15 parts of peach seed and 5-15 parts of safflower.

Preferably, the traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials in parts by weight:

30-40 parts of astragalus mongholicus, 8-12 parts of bighead atractylodes rhizome, 8-12 parts of codonopsis pilosula, 12-18 parts of ligusticum wallichii, 5-8 parts of scorpion, 8-12 parts of cicada slough, 8-12 parts of rhizoma typhonii, 8-12 parts of stiff silkworm, 4-6 parts of ephedra, 2-3 parts of asarum, 12-18 parts of schizonepeta, 12-18 parts of divaricate saposhnikovia root, 12-18 parts of tabasheer, 15-20 parts of angelica sinensis and 30-40 parts of suberect spatholobus stem, 22-28 parts of kudzuvine root, 12-18 parts of tall gastrodia tuber, 15-25 parts of uncaria, 30-40 parts of geranium, 15-25 parts of bitter orange, 8-12 parts of liquoric root, 8-12 parts of incised notopterygium rhizome, 8-12 parts of mint, 8-12 parts of white paeony root, 12-18 parts of Chinese thorowax root, 8-12 parts of turmeric root-tuber, 8-12 parts of nutgrass galingale rhizome, 8-12 parts of peach seed and 8-12 parts of safflower.

The preparation method of the active ingredients of the traditional Chinese medicine composition for treating peripheral facial paralysis comprises the following steps:

adding 8-12 times of water into 21 of astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower from the 29 medicines, decocting for 2 times, 1-2 hours each time, combining extracting solutions, filtering, and concentrating under reduced pressure to form thick paste for; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The preparation method of the traditional Chinese medicine composition for treating peripheral facial paralysis comprises the following steps:

oven drying the active ingredients, pulverizing, sieving with 100 mesh sieve, and making into concentrated pill.

The concentration temperature is 40-60 ℃.

The relative density of the thick paste is 1.25-1.28.

The traditional Chinese medicine has the following sources and effects:

astragalus root, Leguminosae, astragalus root, garden sorrel, hollyhock, baiben, cotton etc., which is the root of astragalus mongholicus or astragalus membranaceus of Leguminosae, [ sexuality ] sweet, slightly warm. [ GUIJING ] enters lung, spleen, liver and kidney meridians. [ FUNCTIONS ] has effects of invigorating qi, consolidating superficial resistance, arresting sweating, relieving depletion, promoting granulation, inducing diuresis, and relieving swelling. Can be used for treating deficiency of vital energy, asthenia, collapse of middle-warmer energy, chronic diarrhea, proctoptosis, hematochezia, metrorrhagia, superficial deficiency, spontaneous perspiration, carbuncle, cellulitis, intractable ulcer, blood deficiency, sallow complexion, internal heat, diabetes, chronic nephritis, albuminuria, diabetes, etc. Huang Qi Zhi has the actions of tonifying qi and strengthening middle energizer, while the raw one is used for strengthening exterior and relieving sore.

Atractylodis rhizoma, Atractylodes macrocephala Koidz.A-tetractylicas macrocephala (Doids.) hand-man-mzz. [ alias ] Flemingium Cirsii, Atractylodes fargesii, Thunz, Populu, Wushu, and Patch, which are a plant of Atractylodes of Compositae. [ PROPERTIES AND WESTERN ] is bitter, sweet and warm. [ GUIJING ] can enter spleen and stomach meridians. [ FUNCTIONS ] Heat-clearing and detoxicating drugs; herbs for clearing heat and drying dampness. [ INDICATIONS ] can invigorate spleen, replenish qi, eliminate dampness, promote diuresis, stop sweating, and prevent miscarriage. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion.

Dangshen, Codonopsis pilosula (Franch.) nannf (alias), ledebouriella root, Codonopsis pilosula, leopard, chinese clematis, and Codonopsis pilosula, which are perennial herbs and have milk. [ PROPERTIES AND FLAVOUR ] neutral in nature, sweet in flavor and slightly sour. [ GUIJING ] can enter spleen and lung meridians. [ EFFECTIVE INDICATIONS ] has effects of invigorating spleen, replenishing qi, invigorating spleen, and nourishing lung. Can be used for treating spleen and lung deficiency, short breath, palpitation, anorexia, loose stool, asthma, cough, internal heat, and diabetes.

Chuan Xiong, Rhizoma Chuanxinong, Rhizoma Belamcandae, Rhizoma corydalis, Rhizoma Ligustici, and Rhizoma Ligustici Chuanxiong. Is rhizome of Umbelliferae plant rhizoma Ligustici Chuanxiong. [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is pungent in flavor and warm in nature. It enters liver, gallbladder and pericardium meridians. [ EFFECTIVE INDICATIONS ] can promote blood circulation, promote the circulation of qi, dispel wind and alleviate pain. Can be used for soothing nerves, relieving headache due to wind, abdominal pain, pricking pain in chest and hypochondrium, traumatic swelling and pain, headache, and rheumatalgia.

Scorpions, and poria with hostwood, which are the dry bodies of Buthus martensii Karsch, a Scorpio of the family scorpiodae. [ PROPERTIES, WEI GUIJING ] is pungent and mild; is toxic. It enters liver meridian. [ EFFECT ] calming endogenous wind, relieving spasm, counteracting toxic pathogen, resolving hard mass, dredging meridians, and relieving pain. [ INDICATIONS ] can be used for treating infantile convulsion, spasm, facial distortion, hemiplegia, tetanus, rheumatism, headache, pyocutaneous disease, and lymphoid tuberculosis.

PERIOSTRACUM Cicadae, [ name of English ] PERIOSTRACUM CICADAE, [ name of name ] PERIOSTRACUM Cicadae, locust shell, locust 34783, cortex cicada, cicada shell, and Calophyllum and PERIOSTRACUM Cicadae are molting shells of cicada family insects after black locust emergence. [ PROPERTIES AND FLAVOUR ] sweet and cold. [ GUIJING ] enters lung and liver meridians. [ FUNCTIONS ] can dispel wind, remove heat, relieve sore throat, promote eruption, remove nebula, and relieve spasm. Can be used for treating wind-heat type common cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion, nebula, convulsion, and tetanus.

Rhizoma Typhonii, Typhonium giganteum Engl (name of Latin school), rhizoma arisaematis, rhizoma amorphophalli, rhizoma Typhonii, furunculosis, and rhizoma Pinelliae Coralli Cantoniensis. Is a plant of the genus Absidia of the family Araceae, and is a unique plant of China. [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is pungent, sweet, warm in nature, and toxic. It enters stomach and liver meridians. [ FUNCTIONS ] can eliminate dampness and phlegm, dispel pathogenic wind, relieve spasm, remove toxic substance, dissipate stagnation and alleviate pain. Can be used for treating apoplexy, facial hemiparalysis, infantile convulsion, epilepsy, tetanus, migraine, etc. caused by wind phlegm; scrofula, subcutaneous nodule, abscess, swelling and toxin and snake bite.

Bombyx Batryticatus, rhizoma Bombyx Batryticatus. Is a dried and hardened insect body which is caused by the death of silkworm larvae due to the infection of beauveria bassiana before spinning. [ PROPERTIES AND FLAVOUR ] has slight fishy smell. Slightly salty in taste. [ FUNCTIONS ] can dispel pathogenic wind, arresting convulsion, resolve phlegm, and dissipate nodulation. Can be used for treating convulsion, sore throat, submandibular lymphadenitis, facial paralysis, and skin pruritus.

Ephedra, herbal ephhedrae, dragon sand, dog bone, inferior phases, inferior salts. Is the grass stem of Ephedra sinica Stapf, Ephedra intermedia Schrenk et C.A. Mey, Ephedra equisetifolia equivalent Bge, belonging to Ephedra sinica of Ephedra of Ephedraceae. [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] is pungent, slightly bitter and warm. It enters lung and bladder meridians. [ EFFECT ] can induce sweat, dispel cold, ventilate lung, relieve asthma, induce diuresis, and alleviate edema.

Asarum, Asarum sieboldii miq. (an alternative name) Asarum sieboldii, zingiber officinale roscoe, striga asiatica, yuxiangsi, and lysimachia christinae. Aristolochiaceae, Asarum, perennial herbs. [ PROPERTIES AND FLAVOUR ] pungent and spicy, and numb tongue. [ EFFECTIVE APPLICATION ] has effects of dispelling pathogenic wind, dispelling cold, inducing resuscitation, relieving pain, warming lung, and eliminating fluid retention.

Herba Schizonepetae, Nepeta cataria L. (also known as "name") is a perennial plant of the genus Nepeta, the family Labiatae, the genus Nepeta, the family Capsella, the family Lepidium, and the family Pseudosciaenae. [ PROPERTIES AND FLAVOUR ] pungent in flavor; slightly bitter; slightly wet in nature. [ GUIJING ] enters lung and liver meridians. [ FUNCTIONS ] can relieve exterior syndrome, dispel pathogenic wind, promote eruption, eliminate sore, and stop bleeding. Can be used for treating common cold, measles without adequate eruption, hematochezia, metrorrhagia, and epistaxis. Dispelling wind; relieving the exterior; promoting eruption; stopping bleeding. Mainly treating cold and fever; headache; itching eyes; cough; swollen and sore throat; measles; abscess and swelling; scabies and sores; bleeding; hematemesis; hematochezia; (ii) metrorrhagia and metrostaxis; postpartum anemic fainting. Can be used for treating common cold, headache, measles, rubella, and initial stage of pyocutaneous disease. Stir-baked into charcoal is indicated for hematochezia, metrorrhagia and metrostaxis and postpartum anemic fainting.

Divaricate saposhnikovia root, [ foreign name ] divaricate saposhnikovia root, [ alternative name ] cuprum, cloudburst, alexie medicinal herbs, hundred branches and hundred species, which is the root of the perennial herb divaricate saposhnikovia root of the Umbelliferae. [ PROPERTIES, WESTERN AND CHANNEL GUIDANGSHEN ] has pungent and sweet taste and mild nature. It enters bladder, liver and spleen meridians. [ EFFECT ] can dispel wind, relieve exterior syndrome, dispel dampness, alleviate pain, stop spasm and stop convulsion. [ INDICATIONS ] exogenous pathogenic exterior syndrome, rubella pruritus, rheumatalgia and tetanus.

Concretio silicea Bambusae seu Schizostachyi, and bamboo sugar. The bleeding liquid stored in bamboo joints after being bitten by parasitic pelargonium sidoides is dried and coagulated into block-shaped substances such as green tangerine peel bamboo of Gramineae. [ PROPERTIES AND FLAVOUR ] sweet and cold. [ FUNCTIONS ] can clear away heat, eliminate phlegm, cool heart and calm convulsion. Coma and delirium due to fever, phlegm and coma in the middle-jiao wind, infantile convulsion and convulsion, epilepsy. Cough due to phlegm-heat.

Angelica, Angelica sinensis, perennial herbs, angelicae sinensis, qina, angelicae sinensis, angelicae gigantean, angelicae cauda, angelicae sinensis and angelicae gigantean. [ PROPERTIES AND FLAVOUR ] sweet in taste; pungent taste; bitter; and (4) temperature. [ GUIJING ] belongs to the liver; a core; spleen meridian. [ efficacy classes ] blood tonics; menstruation regulating medicine; an analgesic. [ EFFECT ] replenishing blood; promoting blood circulation; regulating menstruation and relieving pain; moistening dryness and smoothing intestine. [ INDICATIONS ] syndromes of blood deficiency; menoxenia; amenorrhea; dysmenorrhea; the accumulation of symptoms; (ii) metrorrhagia and metrostaxis; abdominal pain due to deficiency-cold; flaccidity and paralysis; numbness of the skin; intestinal dryness and difficult defecation; severe dysentery with diarrhea; carbuncle, cellulitis, sore and ulcer; injury from falling.

Caulis Spatholobi, Millettiae reticulatae Benth, also known as caulis et folium Pavettae Hongkongensis, is the dried stem of Spathobatus suberectus Dunn of Leguminosae. [ PROPERTIES AND FLAVOUR GUIDING CHANNEL ] bitter, sweet and warm. It enters liver and kidney meridians. [ FUNCTIONS ] can tonify blood, promote blood circulation, and dredge collaterals. Can be used for treating menoxenia, blood deficiency, sallow complexion, numbness, paralysis, and rheumatalgia.

Kudzu Root, Radix Puerariae (the name of English) Root, Lobed Kudzuvine Root, is the dried Root of Pueraria lobata (Willd.) Ohwi, a leguminous plant. [ PROPERTIES AND FLAVOUR ] is sweet, pungent and mild. [ GUIJING ] enters spleen and stomach meridians. [ FUNCTIONS ] has the effects of invigorating yang, expelling pathogenic factors from muscles, promoting eruption, relieving diarrhea, relieving restlessness, and relieving fever. It can be used for treating typhoid fever, headache, dysphoria with smothery sensation, diabetes, diarrhea, dysentery, macula, hypertension, angina pectoris, and deafness.

Gastrodia elata, Gastrodia elata Bl. (alternative name) Thymus chinensis, Pleurospermum, Lygodium japonicum, HEISAO, Shencao, ghost Po, Gastrodia elata, Dioscorea opposita, and Poa alba are perennial herbs of Gastrodia of Orchidaceae. [ PROPERTIES, WEI GUIJING ] is sweet and neutral and enters liver meridian. [ FUNCTIONS ] can extinguish wind and stop spasm, pacify liver and subdue yang, dispel wind and dredge.

Ramulus Uncariae cum uncis, Uncaria rhynchophylla (Miq.) Miq. ex Havil. (also known as Achilles) ramulus Uncariae cum uncis, caulis Seu folium Chloranthi Spicati, radix Zanthoxyli Avicennae, and radix Berchemiae Lineatae. Is evergreen vine of Uncaria genus of Rubiaceae family. [ PROPERTIES AND FLAVOUR ] bitter and sweet; is slightly cold. [ GUIJING ] liver meridian; the heart meridian. [ FUNCTIONS ] can clear away heat and calm the liver; to stop endogenous wind and relieve convulsions. [ INDICATIONS ] infantile convulsion; night crying; the heat moves wind; eclampsia; vertigo due to liver yang; liver fire distending pain of the head.

Geranium wilfordii Maxim, Geranium wilfordii, Geranium laevigatum, Geranium robustum, Geranium coronarium, Geranium willd, Geranium wilfordii Geranium Willd, Geranium wilfordii, Geranium nepalenii, Geranium sibirica, Geranium tuberosum, Geranium alpinum and Geranium alpinum (or Geranium carolinaum L., Geranium carinatum L., dry and dry whole plant with fruit, such as [ sex odor ] octanes, bitter, Pink. ] channel-tropism, liver, kidney and spleen channel-function indications ] rheumatism-expelling, channels-dredging, and collaterals-checking, and pain-relieving rheumatism, numbness, pain, soreness and diarrhea.

Fructus Aurantii is dried immature fruit of Citrus aurantium L. of Rutaceae and its cultivar. [ PROPERTIES AND WESTERN ] bitter, pungent, sour and warm. [ FUNCTIONS ] can break qi, remove phlegm, and resolve stagnation. It is used to treat chest and diaphragm phlegm stagnation, chest fullness, hypochondriac distention, food retention, belching, vomiting, diarrhea, anal prolapse, and uterine prolapse.

Licorice, known as Glycyrrhiza uralensis Fisch, also known as Laurus domestica, Glycyrrhiza uralensis and Glycyrrhiza glabra. Leguminous and glycyrrhiza herbs belong to perennial herbs, and the roots and the rhizomes are strong, so the Chinese herbal medicine is a tonifying Chinese herbal medicine. [ PROPERTIES AND FLAVOUR ] sweet, mild and nontoxic. [ GUIJING ] enters spleen, stomach and lung meridians. [ FUNCTIONS ] can tonify qi and strengthen the middle warmer; relieving spasm and pain; moistening lung to arrest cough; purging pathogenic fire and removing toxic substances; harmonize the drugs. Mainly lassitude and poor appetite; emaciation and yellow face; palpitation and shortness of breath; abdominal pain and loose stool; limb spasm and pain; irritability; cough and asthma; swollen and sore throat; carbuncle sore and swelling pain; infantile fetal toxicity; and drug and food poisoning. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.

Notopterygium root, Notopterygium incissum, also named as Qiang, Qiang-protecting, Huwang, Qiangshu, Jatropha, Hedera, Umbelliferae, Notopterygium, perennial herbs. [ PROPERTIES, WESTERN AND CHANNEL FENCH ] is pungent, bitter and warm. Enter bladder and kidney meridians. [ FUNCTIONS ] can dispel exterior cold, dispel wind-damp, and promote joint movement. It is used to treat common cold, wind-cold, headache, anhidrosis, arthralgia due to wind-cold-dampness, stiff neck, soreness of joints, edema due to wind-damp, carbuncle, sore and toxin.

Mint, [ academic name ] Mentha canadensis l. [ alternative name ] peppermint, Mentha aquatica, common goldenrod herb, red sage, passion flower, wild mint, evening primrose, south mint, peppermint, caraway, dog meat, motherwort, sambucus chinensis, peppermint, red sage, wild sage, peppermint, five spices, and the like. The root of the triple energizer is of the genus Labiatae. [ PROPERTIES AND FLAVOUR ] pungent and cool. [ GUIJING ] enters lung meridian and liver meridian. [ EFFECT ] can dispel wind-heat, clear heat, relieve sore throat, promote eruption, soothe liver, and move qi. [ INDICATIONS ] can dispel wind, dispel heat, repel foul, remove toxic substance, treat affection of exogenous wind-heat, headache, sore throat, dyspepsia, flatulence, aphtha, toothache, scabies, urticaria, early stage of epidemic febrile disease, rubella pruritus, stagnation of qi due to depression of the liver, chest distress, and hypochondriac pain.

White peony root, Paeonia lactiflora pall. (also known as "alias"), white peony root, flower seed, white peony root, golden peony root, Hangzhou peony root, white peony root, raw white peony root, stir-fried Hangzhou peony root, wine white peony root, vinegar white peony root, burnt white peony root, white peony root charcoal and the like, which is a dried root of Paeonia lactiflora pall. [ PROPERTIES AND FLAVOUR ] KUAISUAN, and cool. [ GUIJING ] enters liver and spleen meridians. [ FUNCTIONS ] can nourish blood, soften liver, relieve the middle energizer, alleviate pain, astringe yin and astringe sweat. It is indicated for pain in chest, abdomen, hypochondrium, dysentery, abdominal pain, spontaneous sweating, night sweat, fever due to yin deficiency.

Yu jin, the name of Chinese medicine. Is dried root tuber of Curcuma wenyujin Y, H, Chenet C.Ling, Curcuma longa LongaL, Curcuma kwangtungensis S.G.Lee et C.F.Liang or Curcuma zedoaria alpha eocaulis Val. [ PROPERTIES AND FLAVOUR ] is pungent, bitter and cool. [ GUIJING ] enters heart, lung and liver meridians. Move qi and relieve depression, cool blood and break blood stasis. It is indicated for pain in chest, abdomen and hypochondrium, mania due to loss of heart, coma due to fever, hematemesis, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, and jaundice. [ FUNCTIONS ] can promote the circulation of qi, relieve depression, remove heat from the blood and remove blood stasis. It is indicated for pain in chest, abdomen and hypochondrium, mania due to loss of heart, coma due to fever, hematemesis, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, and jaundice.

Bupleurum, Radix Bupleuri, peruvian root, duzu, mountain mustard, rue, bupleurum, etc. [ PROPERTIES, WESTERN AND CHANNEL TROPISM ] is slightly cold in nature, bitter and pungent in flavor; it enters liver meridian and gallbladder meridian. [ FUNCTIONS ] can induce diaphoresis, purge heat, soothe the liver, relieve depression, and elevate yang qi. Liver qi stagnation, distending pain in chest and hypochondrium, rectocele, metrorrhagia, and menoxenia.

Cyperus rotundus (L.) Ration, Cyperus rotundus (L.) Ramsl, Turkey, Thymus fasciatus (L.) Roxb, and Digitalis purpurea (L.) Ramsl belonging to Cyperaceae family. [ PROPERTIES AND WESTERN PROPERTIES ] is pungent, slightly bitter, sweet and neutral. [ GUIJING ] enters liver and triple energizer meridians. [ FUNCTIONS ] the unprocessed one has the actions of relieving exterior syndrome and pain, stir-baked with vinegar to remove food retention and relieve pain, stir-baked with wine to remove meridian obstruction and relieve pain, and stir-baked with charcoal to stop bleeding. Has the effects of regulating qi, relieving qi stagnation, regulating menstruation and relieving pain, and can be used for treating stagnation of qi due to depression of the liver, fullness and distention in chest and hypochondrium, abdominal distention and pain, hernia pain, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia, leukorrhagia, and threatened abortion.

Peach kernel, name of traditional Chinese medicine. Is dried mature seed of Prunus persica (L.) Batsch or Prunus davidiana (Carr.) Franch, a Rosaceae plant. [ CHARACTERISTIC AND FLAVOUR ] has light smell, slightly bitter taste and mild nature. [ GUIJING ] enters heart, liver and large intestine meridians. [ FUNCTIONS ] can be used for treating abdominal mass, pulmonary abscess, intestinal abscess, traumatic injury, amenorrhea, dysmenorrhea, and puerperal pain due to blood stasis. Moistening dryness, smoothing intestine, treating various kinds of open-circuit symptoms caused by blood stasis, treating internal carbuncle, activating blood circulation and removing blood stasis.

Safflower, name of Chinese medicine. Is dried flower of Carthamus tinctorius L. [ PROPERTIES AND FLAVOUR ] pungent in flavor and warm in nature. [ GUIJING ] returning to the heart and liver meridians. [ EFFECT ] the product has effects of promoting blood circulation, dredging channels, removing blood stasis, and relieving pain. [ INDICATIONS ] can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain.

The invention also provides a traditional Chinese medicine preparation for treating peripheral facial paralysis, which is prepared into other different dosage forms, including powder, tablets, capsules, granules, solutions or suspensions, by applying the traditional Chinese medicine composition for treating peripheral facial paralysis and a pharmaceutically acceptable carrier.

Pharmaceutically acceptable carriers of the invention include, but are not limited to, the following:

diluent agent: zinc oxide, calamine, starch, powdered sugar, lactose, dextrin, microcrystalline cellulose, inorganic salts, sugar alcohols, etc.

Adhesive: gelatin, polyethylene glycol, cellulose derivatives, lard, petrolatum, silicone oil, lanolin, cellulose, gums, raw rubber, lead soap, lanolin, and the like.

Organic solvent: boric acid, lead acetate, copper sulfate, zinc sulfate, aluminum acetate, rivanol, nitrofural, neomycin, potassium permanganate, diethyl ether, ethanol, acetone and the like.

Disintegrating agent: starch, sodium carboxymethyl starch, cellulose derivatives, crospovidone, and the like.

Lubricant: magnesium stearate, aerosil, talcum powder, polyethylene glycol, triethanolamine, sodium lauryl sulfate, stearic acid, cetyl alcohol, polyethylene glycol, monoglyceride, span, tween and the like.

Emulsifier: lard, vaseline, silicone oil, lanolin, polyethylene glycol, cellulose, etc.

Cosolvent: water, ethanol, glycerol, propylene glycol, liquid paraffin, vegetable oil, dimethyl sulfoxide, azone, etc.

Flavoring agent: sucrose, monosaccharide, aromatic, etc.

Preservative: benzoic acid, sorbic acid, methyl esters, ethyl esters, propyl esters, and the like.

Plasticizer: castor oil, rosin, and the like.

Film-forming materials: cotton, corn and organic glass.

The preparation method of each Chinese medicinal preparation formulation comprises the following steps:

1. powder preparation:

drying and crushing active ingredients of the traditional Chinese medicine composition for treating peripheral facial paralysis to obtain powder;

2. and (3) tablet preparation:

the active ingredients of the traditional Chinese medicine composition for treating peripheral facial paralysis are dried, crushed and tabletted to obtain the tablet.

3. And (3) capsule preparation:

drying and crushing active ingredients of the traditional Chinese medicine composition for treating peripheral facial paralysis, and then filling the active ingredients into hollow capsules or sealing the hollow capsules into elastic soft capsules to obtain capsules; the materials for forming the hollow hard capsule shell or the elastic soft capsule shell are gelatin, glycerin, water and other medicinal materials.

4. Granules:

drying and crushing the active ingredients of the traditional Chinese medicine composition for treating peripheral facial paralysis, mixing the crushed active ingredients with proper auxiliary materials, and granulating to obtain granules; the auxiliary materials comprise diluent, absorbent, wetting agent, adhesive, flavoring agent and effervescent auxiliary materials.

5. Solution or suspension:

the active ingredients of the traditional Chinese medicine composition for treating peripheral facial paralysis are dissolved in water, vegetable oil or other medicinal liquid solvents to obtain a solution or a suspension.

The invention has the beneficial effects that:

the traditional Chinese medicine composition has the effects of dispelling wind, dredging collaterals, promoting blood circulation and nourishing tendons, and is mainly used for treating peripheral facial paralysis. In the traditional Chinese medicine composition, astragalus, codonopsis pilosula and bighead atractylodes rhizome have the effects of tonifying qi and strengthening spleen; the ephedra, the fineleaf schizonepeta herb and the manchurian wildginger can relieve wind and remove exterior syndrome and disperse wind-cold; for wind-treating first treating blood, angelica, ligusticum wallichii and white peony root are used for nourishing blood and promoting blood circulation; radix Saposhnikoviae, Notopterygii rhizoma, and herba Menthae for dispelling pathogenic wind; rhizoma Gastrodiae, ramulus Uncariae cum uncis, herba Erodii seu Geranii, and caulis Spatholobi can pacify liver and stop endogenous wind; concretio silicea Bambusae seu Schizostachyi, Scorpio, rhizoma Typhonii, and periostracum Cicadae for dispelling pathogenic wind and phlegm; radix Curcumae, bupleuri radix, and rhizoma Cyperi can relieve depression and tranquilize mind; peach kernel and safflower have the functions of promoting blood circulation and removing blood stasis; the liquorice coordinates the effects of the other drugs in the recipe; the medicine mainly comprises the components and has the functions of dispelling wind and dredging collaterals, activating blood and nourishing tendons, and tonifying qi and spleen; the traditional Chinese medicine composition accords with the monarch, minister, assistant and guide, has reasonable formula and obvious curative effect.

Through a large number of experimental researches, 29 Chinese herbal medicines are selected and matched to be used as a medicine, the traditional Chinese medicine composition accords with the traditional Chinese medicine theory and the modern medical theory, and has no toxic or side effect; the traditional Chinese medicines supplement each other and cooperate with each other, and the traditional Chinese medicine has the effects of dispelling wind, dredging collaterals, promoting blood circulation, nourishing tendons, tonifying qi and strengthening spleen, has targeted curative effect on peripheral facial paralysis, accords with the monarch, minister, assistant and guide, has reasonable formula and obvious curative effect.

Detailed Description

The present invention will be described in detail below with reference to specific examples.

Example 1

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 20g of astragalus membranaceus, 5g of bighead atractylodes rhizome, 5g of codonopsis pilosula, 10g of ligusticum wallichii, 1g of scorpion, 7g of periostracum cicada, 5g of rhizoma typhonii, 5g of stiff silkworm, 3g of ephedra, 1g of asarum, 10g of schizonepeta, 10g of radix saposhnikoviae, 10g of concretio silicea bambusae, 10g of angelica sinensis, 20g of caulis spatholobi, 20g of radix puerariae, 10g of rhizoma gastrodiae, 10g of uncaria, 20g of geranium, 10g of fructus aurantii, 7g of liquorice, 5g of notopterygium root, 5g of mint, 5g of radix paeoniae alba, 10 g.

The preparation method of the active ingredients of the traditional Chinese medicine composition comprises the following steps:

adding 8 times of water into 21 of astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower from the 29 medicines, decocting for 2 times, 1 hour each time, combining extracting solutions, filtering, decompressing, and concentrating into thick paste with the relative density of 1.25 at 40 ℃ for later use; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The traditional Chinese medicine composition of the embodiment is prepared into pills, and the preparation method comprises the following steps:

Example 2

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 25g of astragalus membranaceus, 7g of bighead atractylodes rhizome, 7g of codonopsis pilosula, 12g of ligusticum wallichii, 2g of scorpion, 8g of periostracum cicada, 7g of rhizoma typhonii, 7g of stiff silkworm, 4g of ephedra, 2g of asarum, 12g of schizonepeta, 12g of radix saposhnikoviae, 12g of concretio silicea bambusae, 15g of angelica sinensis, 25g of caulis spatholobi, 22g of radix puerariae, 12g of rhizoma gastrodiae, 15g of uncaria, 25g of geranium wilfordii, 15g of fructus aurantii, 8g of liquorice, 7g of notopterygium root, 7g of mint, 7g of radix paeoniae alba.

adding 10 times of water into 21 of astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower from the 29 medicines, decocting for 2 times, 1.5 hours each time, combining extracting solutions, filtering, decompressing, and concentrating into thick paste with the relative density of 1.26 at 45 ℃ for later use; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

Example 3

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 30g of astragalus membranaceus, 8g of bighead atractylodes rhizome, 8g of codonopsis pilosula, 12g of ligusticum wallichii, 4g of scorpion, 8g of periostracum cicada, 8g of rhizoma typhonii, 8g of stiff silkworm, 4g of ephedra, 2g of asarum, 12g of schizonepeta, 12g of radix saposhnikoviae, 12g of concretio silicea bambusae, 15g of angelica sinensis, 30g of caulis spatholobi, 22g of radix puerariae, 12g of rhizoma gastrodiae, 15g of uncaria, 30g of geranium, 15g of fructus aurantii, 8g of liquorice, 8g of notopterygium root, 8g of mint, 8g of radix paeoniae alba, 12 g.

21 kinds of medicines of astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, Chinese angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower are taken from the 29 medicines, 12 times of water is added, the medicines are decocted for 2 times, 2 hours each time, extracting solutions are combined, filtered and decompressed, and concentrated into thick paste with the relative density; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

Example 4

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 32g of astragalus membranaceus, 9g of bighead atractylodes rhizome, 9g of codonopsis pilosula, 14g of ligusticum wallichii, 5g of scorpion, 9g of periostracum cicada, 9g of rhizoma typhonii, 9g of stiff silkworm, 5g of ephedra, 3g of asarum, 14g of schizonepeta, 14g of radix saposhnikoviae, 14g of concretio silicea bambusae, 18g of angelica sinensis, 30g of caulis spatholobi, 24g of radix puerariae, 14g of rhizoma gastrodiae, 18g of uncaria, 30g of geranium wilfordii, 18g of fructus aurantii, 9g of liquorice, 9g of notopterygium root, 9g of mint, 9g of radix paeoniae alba.

adding 9 times of water into 21 of astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower from the 29 medicines, decocting for 2 times, 1 hour each time, combining extracting solutions, filtering, concentrating at 60 ℃ under reduced pressure to form thick paste with the relative density of 1.28 for later; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The traditional Chinese medicine composition is prepared into powder, and the preparation method comprises the following steps:

drying the active ingredients, crushing, and sieving with a 100-mesh sieve to obtain the powder.

Example 5

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 35g of astragalus membranaceus, 10g of bighead atractylodes rhizome, 10g of codonopsis pilosula, 15g of ligusticum wallichii, 7g of scorpion, 10g of periostracum cicada, 10g of rhizoma typhonii, 10g of stiff silkworm, 5g of ephedra, 3g of asarum, 15g of schizonepeta, 15g of radix saposhnikoviae, 15g of concretio silicea bambusae, 18g of angelica sinensis, 35g of caulis spatholobi, 25g of radix puerariae, 15g of rhizoma gastrodiae, 20g of uncaria, 35g of geranium wilfordii, 20g of fructus aurantii, 10g of liquorice, 10g of notopterygium root, 10g of mint, 10g of radix paeoniae alba.

adding 8 times of water into 21 of the 20 medicines such as astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, radix bupleuri, rhizoma cyperi and safflower, decocting for 2 times, 1 hour each time, combining extracting solutions, filtering, decompressing, and concentrating at 42 ℃ to form thick paste with the relative density of 1.25 for later use; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The preparation method of the traditional Chinese medicine composition prepared in the embodiment is to prepare tablets, and comprises the following steps:

oven drying the active ingredients, pulverizing, mixing with appropriate amount of starch and dextrin, sieving with 100 mesh sieve, and tabletting to obtain tablet.

Example 6

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 40g of astragalus membranaceus, 12g of bighead atractylodes rhizome, 12g of codonopsis pilosula, 18g of ligusticum wallichii, 8g of scorpion, 12g of periostracum cicada, 12g of rhizoma typhonii, 12 parts of stiff silkworm, 6g of ephedra, 3g of asarum, 18g of schizonepeta, 18g of radix saposhnikoviae, 18g of concretio silicea bambusae, 20g of angelica sinensis, 40g of caulis spatholobi, 28g of radix puerariae, 18g of rhizoma gastrodiae, 25g of uncaria, 40g of geranium wilfordii, 25g of fructus aurantii, 12g of liquorice, 12g of notopterygium root, 12g of mint, 12g of radix paeoniae alba.

adding 9 times of water into 21 of the 20 medicines, namely astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, Chinese angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower, decocting for 2 times, 1 hour each time, combining extracting solutions, filtering, decompressing, and concentrating into thick paste with the relative density of 1.26 at 45 ℃ for later; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The traditional Chinese medicine composition of the embodiment is prepared into capsules, and the preparation method comprises the following steps:

drying the active ingredients, crushing, sieving with a 100-mesh sieve, and filling into hollow capsules to obtain the capsules.

Example 7

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 30g of astragalus membranaceus, 12g of bighead atractylodes rhizome, 10g of codonopsis pilosula, 12g of ligusticum wallichii, 8g of scorpion, 11g of periostracum cicada, 9g of rhizoma typhonii, 10g of stiff silkworm, 6g of ephedra, 2g of asarum, 14g of schizonepeta, 16g of radix saposhnikoviae, 17g of concretio silicea bambusae, 16g of angelica sinensis, 33g of caulis spatholobi, 23g of radix puerariae, 18g of rhizoma gastrodiae, 22g of uncaria, 37g of geranium wilfordii, 19g of fructus aurantii, 8g of liquorice, 9g of notopterygium root, 9g of mint, 10g of radix paeoniae alba.

adding 9 times of water into 21 of the 20 medicines, namely astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, Chinese angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower, decocting for 2 times, 1 hour each time, combining extracting solutions, filtering, decompressing, and concentrating at 60 ℃ into thick paste with the relative density of 1.27 for later; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The traditional Chinese medicine composition of the embodiment is prepared into granules, and the preparation method comprises the following steps:

mixing the active ingredients with appropriate amount of starch and sugar powder, and granulating to obtain granule.

Example 8

The traditional Chinese medicine composition for treating peripheral facial paralysis is prepared from the following raw materials: 50g of astragalus membranaceus, 15g of bighead atractylodes rhizome, 15g of codonopsis pilosula, 20g of ligusticum wallichii, 10g of scorpion, 15g of periostracum cicada, 15g of rhizoma typhonii, 15g of stiff silkworm, 7g of ephedra, 5g of asarum, 20g of schizonepeta, 20g of radix saposhnikoviae, 20g of concretio silicea bambusae, 30g of angelica sinensis, 50g of caulis spatholobi, 30g of radix puerariae, 20g of rhizoma gastrodiae, 30g of uncaria, 50g of geranium wilfordii, 30g of fructus aurantii, 15g of liquorice, 15g of notopterygium root, 15g of mint, 15g of radix paeoniae alba.

adding 9 times of water into 21 of the 20 medicines, namely astragalus, bighead atractylodes rhizome, ligusticum wallichii, rhizoma typhonii, ephedra, asarum, schizonepeta, divaricate saposhnikovia root, Chinese angelica, suberect spatholobus stem, kudzuvine root, tall gastrodia tuber, uncaria, geranium wilfordii, liquorice, notopterygium root, mint, white paeony root, Chinese thorowax root, nutgrass galingale rhizome and safflower, decocting for 2 times, 2 hours each time, combining extracting solutions, filtering, decompressing, and concentrating at 55 ℃ to form thick paste with the relative density of 1.28 for; pulverizing the rest 8 materials into coarse powder, and mixing with the above soft extract to obtain active ingredient.

The traditional Chinese medicine composition is prepared into a solution, and the preparation method comprises the following steps:

mixing the active ingredients with appropriate amount of sugar and water to obtain solution.

Summary of clinical trials

1 basic data

50 patients with peripheral facial paralysis were observed, aged 20-70 years.

2 method of treatment

After taking the concentrated pill of example 3 of the present invention, 2 times/day and 1 pill/time for 3 months, the change of symptoms after treatment was observed.

3 criteria for judgment of therapeutic effects

And (3) curing: clinical symptoms such as facial nerve edema, demyelination, axonal degeneration, atrophy and the like are completely disappeared, facial distortion characterization is disappeared, and the mental state is good and active; during the 1 year follow-up period, no abnormal symptoms appeared;

the method has the following advantages: the clinical symptoms are improved to a certain extent, the facial distortion is characterized to be improved, qi and blood are smooth, the functions of meridians and tendons are repaired, and the mental state is good;

and (4) invalidation: clinical symptoms and signs did not improve significantly.

4 results are shown in table 1.

TABLE 1 therapeutic results

	Cure of disease	Effective invalidation	Effective rate (%)
				Therapeutic effect	48	2 0	100%

Clinical results show that: the total effective rate of the invention to peripheral facial paralysis patients is 100%, and the result shows that the invention has good efficacies of dispelling wind and dredging collaterals, promoting blood circulation and strengthening tendons, and replenishing qi and invigorating spleen, and has targeted curative effect on peripheral facial paralysis.

Typical cases

Case of taking

1. Liao xxx, Hainan Suiyi, Man, 27 years old, due to wind-cold entering the meridians of the middle-jiao, qi and blood obstruction, functional disorder of the meridians and tendons, and loss of the muscles and tendons to restrain, facial distortion occurs. After the concentrated pill of the invention in the embodiment 3 is taken for 1 pill/time and 2 times/day for 3 months, the facial distortion is better, the qi and blood are smooth, the function of the meridians and the tendons are repaired, and the mental state is good.

2. Huxxx, Hubei Wuhan City, female, age 45, due to overstrain and insufficient healthy qi, the body is empty and weak in the veins, the defensive exterior is not firm, facial nerve edema is unconscious, the language is vague, and the life cannot be self-managed. After the powder of the embodiment 4 of the invention is taken for 1 bag/time and 2 times/day for 3 months, the face returns to normal, the mouth and eyes move freely, the language is smooth, the functions of the meridians and the tendons are restored, and the mental state is good.

3. Linxxx, south fluidic city of Jiangxi, male, age 33, paroxysmal facial distortion, facial neuralgia, slurred speech. After taking the tablet of the invention in example 5 1 tablet/time and 2 times/day for 3 months, the face returns to normal, the neuralgia disappears, the mouth and eyes move freely, the language is smooth, the function of the meridians and the tendons is restored, and the mental state is good.

Although the invention has been described in detail hereinabove by way of general description, specific embodiments and experiments, it will be apparent to those skilled in the art that many modifications and improvements can be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims

1. The traditional Chinese medicine composition for treating peripheral facial paralysis is characterized by being prepared from the following raw materials in parts by weight: 20-50 parts of astragalus root, 5-15 parts of white atractylodes rhizome, 5-15 parts of codonopsis pilosula, 10-20 parts of ligusticum wallichii, 1-10 parts of scorpion, 7-15 parts of cicada slough, 5-15 parts of rhizoma typhonii, 5-15 parts of stiff silkworm, 3-7 parts of ephedra herb, 1-5 parts of asarum, 10-20 parts of schizonepeta, 10-20 parts of divaricate saposhnikovia root, 10-20 parts of tabasheer, 10-30 parts of angelica and 20-50 parts of suberect spatholobus stem, 20-30 parts of kudzuvine root, 10-20 parts of tall gastrodia tuber, 10-30 parts of uncaria, 20-50 parts of geranium, 10-30 parts of bitter orange, 7-15 parts of liquoric root, 5-15 parts of incised notopterygium rhizome, 5-15 parts of mint, 5-15 parts of white paeony root, 10-20 parts of Chinese thorowax root, 7-15 parts of turmeric root-tuber, 7-15 parts of nutgrass galingale rhizome, 5-15 parts of peach seed and 5-15 parts of safflower.

2. The traditional Chinese medicine composition for treating peripheral facial paralysis as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 30-40 parts of astragalus mongholicus, 8-12 parts of bighead atractylodes rhizome, 8-12 parts of codonopsis pilosula, 12-18 parts of ligusticum wallichii, 5-8 parts of scorpion, 8-12 parts of cicada slough, 8-12 parts of rhizoma typhonii, 8-12 parts of stiff silkworm, 4-6 parts of ephedra, 2-3 parts of asarum, 12-18 parts of schizonepeta, 12-18 parts of divaricate saposhnikovia root, 12-18 parts of tabasheer, 15-20 parts of angelica sinensis and 30-40 parts of suberect spatholobus stem, 22-28 parts of kudzuvine root, 12-18 parts of tall gastrodia tuber, 15-25 parts of uncaria, 30-40 parts of geranium, 15-25 parts of bitter orange, 8-12 parts of liquoric root, 8-12 parts of incised notopterygium rhizome, 8-12 parts of mint, 8-12 parts of white paeony root, 12-18 parts of Chinese thorowax root, 8-12 parts of turmeric root-tuber, 8-12 parts of nutgrass galingale rhizome, 8-12 parts of peach seed and 8-12 parts of safflower.

3. The Chinese medicinal composition for treating peripheral facial paralysis according to claim 1, wherein the preparation method of the active ingredients comprises the following steps:

4. The Chinese medicinal composition for treating peripheral facial paralysis as claimed in claim 3, wherein the preparation method of the pill comprises the following steps:

5. The Chinese medicinal composition for treating peripheral facial paralysis according to claim 3, wherein: the concentration temperature is 40-60 ℃.

6. The Chinese medicinal composition for treating peripheral facial paralysis according to claim 3, wherein: the relative density of the thick paste is 1.25-1.28.

7. A Chinese medicinal preparation for treating peripheral facial paralysis, which comprises the Chinese medicinal composition for treating peripheral facial paralysis according to any one of claims 1-6 and pharmaceutically acceptable carrier.