CN115697338A - 甲基取代的苯并二噁唑类化合物及其应用 - Google Patents
甲基取代的苯并二噁唑类化合物及其应用 Download PDFInfo
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- CN115697338A CN115697338A CN202180041386.9A CN202180041386A CN115697338A CN 115697338 A CN115697338 A CN 115697338A CN 202180041386 A CN202180041386 A CN 202180041386A CN 115697338 A CN115697338 A CN 115697338A
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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Abstract
新的甲基取代的苯并二噁唑类化合物，及其在制备治疗相关疾病的药物中的应用。具体公开了式(P)所示化合物或其药学上可接受的盐。
Description
PCT国内申请，说明书已公开。
Claims (15)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020105245918 | 2020-06-10 | ||
| CN202010524591 | 2020-06-10 | ||
| CN2020108788297 | 2020-08-27 | ||
| CN202010878829 | 2020-08-27 | ||
| CN2021105739804 | 2021-05-25 | ||
| CN202110573980 | 2021-05-25 | ||
| PCT/CN2021/099432 WO2021249492A1 (zh) | 2020-06-10 | 2021-06-10 | 甲基取代的苯并二噁唑类化合物及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115697338A true CN115697338A (zh) | 2023-02-03 |
| CN115697338B CN115697338B (zh) | 2024-08-09 |
Family
ID=78846841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180041386.9A Active CN115697338B (zh) | 2020-06-10 | 2021-06-10 | 甲基取代的苯并二噁唑类化合物及其应用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20230234968A1 (zh) |
| EP (1) | EP4166142A4 (zh) |
| CN (1) | CN115697338B (zh) |
| WO (1) | WO2021249492A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115667238A (zh) * | 2020-12-25 | 2023-01-31 | 四川海思科制药有限公司 | 一种五并五元环衍生物及其在医药上的应用 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116323599A (zh) | 2020-08-06 | 2023-06-23 | 加舒布鲁姆生物公司 | 杂环glp-1激动剂 |
| EP4204415A1 (en) | 2020-08-28 | 2023-07-05 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2022202864A1 (ja) | 2021-03-24 | 2022-09-29 | 塩野義製薬株式会社 | 縮合環を有するｇｌｐ－１受容体作動薬を含有する医薬組成物 |
| CN117177970A (zh) * | 2021-04-30 | 2023-12-05 | 上海翰森生物医药科技有限公司 | 多环类衍生物调节剂、其制备方法和应用 |
| TWI843104B (zh) | 2021-05-20 | 2024-05-21 | 美商美國禮來大藥廠 | 類升糖素肽1受體促效劑 |
| WO2023038039A1 (ja) | 2021-09-08 | 2023-03-16 | 塩野義製薬株式会社 | 抗肥満作用の関与する疾患の予防及び治療用医薬 |
| WO2023057414A1 (en) | 2021-10-05 | 2023-04-13 | Astrazeneca Ab | Certain octahydrofuro[3,4- b]pyrazines as glp-1 receptor modulators |
| WO2023057429A1 (en) | 2021-10-05 | 2023-04-13 | Astrazeneca Ab | Certain 2,5-diazabicyclo[4.2.0]octanes and octahydrofuro[3,4- b]pyrazines as glp-1 receptor modulators |
| KR20240073108A (ko) | 2021-10-05 | 2024-05-24 | 아스트라제네카 아베 | Glp-1 수용체 조절제로서의 특정 2,5-디아자바이시클로[4.2.0]옥탄 |
| CN118401519A (zh) | 2021-10-25 | 2024-07-26 | 拓臻制药公司 | 作为glp-1r激动剂的化合物 |
| WO2023111145A1 (en) | 2021-12-16 | 2023-06-22 | Astrazeneca Ab | Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators |
| WO2023111144A1 (en) | 2021-12-16 | 2023-06-22 | Astrazeneca Ab | Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators |
| KR20240125003A (ko) * | 2021-12-23 | 2024-08-19 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | Glp-1 수용체 작용제의 약학적으로 허용 가능한 염, 결정 형태 및 이의 제조방법 |
| WO2023125896A1 (zh) * | 2021-12-31 | 2023-07-06 | 海思科医药集团股份有限公司 | 一种glp-1激动剂中间体及其制备方法及在医药中的用途 |
| WO2023164050A1 (en) * | 2022-02-23 | 2023-08-31 | Terns Pharmaceuticals, Inc. | Compounds as glp-1r agonists |
| TW202408504A (zh) * | 2022-06-23 | 2024-03-01 | 大陸商西藏海思科製藥有限公司 | 噻吩[2,3-d]咪唑類化合物的鹽及其晶型和在醫藥上的用途 |
| WO2023246833A1 (zh) * | 2022-06-23 | 2023-12-28 | 西藏海思科制药有限公司 | 一种五并五元环衍生物的药物组合物及其在医药上的应用 |
| WO2024102625A1 (en) | 2022-11-11 | 2024-05-16 | Eli Lilly And Company | Glucagon-like peptide 1 receptor agonists |
| WO2024107781A1 (en) | 2022-11-16 | 2024-05-23 | Eli Lilly And Company | Glucagon-like peptide 1 receptor agonists |
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| US20190225604A1 (en) * | 2016-09-26 | 2019-07-25 | Chugai Seiyaku Kabushiki Kaisha | Pyrazolopyridine derivative having glp-1 receptor agonist effect |
| CN110325530A (zh) * | 2016-12-16 | 2019-10-11 | 辉瑞大药厂 | Glp-1受体激动剂及其用途 |
| WO2019239371A1 (en) * | 2018-06-15 | 2019-12-19 | Pfizer Inc. | Glp-1 receptor agonists and uses thereof |
| WO2019239319A1 (en) * | 2018-06-13 | 2019-12-19 | Pfizer Inc. | Glp-1 receptor agonists and uses thereof |
| CN111247151A (zh) * | 2018-05-25 | 2020-06-05 | 正大天晴药业集团股份有限公司 | 2,3-二氢-1h-吡咯嗪-7-甲酰胺类衍生物及其应用 |
-
2021
- 2021-06-10 WO PCT/CN2021/099432 patent/WO2021249492A1/zh unknown
- 2021-06-10 EP EP21822762.7A patent/EP4166142A4/en active Pending
- 2021-06-10 CN CN202180041386.9A patent/CN115697338B/zh active Active
- 2021-06-10 US US18/009,481 patent/US20230234968A1/en active Pending
Patent Citations (5)
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| US20190225604A1 (en) * | 2016-09-26 | 2019-07-25 | Chugai Seiyaku Kabushiki Kaisha | Pyrazolopyridine derivative having glp-1 receptor agonist effect |
| CN110325530A (zh) * | 2016-12-16 | 2019-10-11 | 辉瑞大药厂 | Glp-1受体激动剂及其用途 |
| CN111247151A (zh) * | 2018-05-25 | 2020-06-05 | 正大天晴药业集团股份有限公司 | 2,3-二氢-1h-吡咯嗪-7-甲酰胺类衍生物及其应用 |
| WO2019239319A1 (en) * | 2018-06-13 | 2019-12-19 | Pfizer Inc. | Glp-1 receptor agonists and uses thereof |
| WO2019239371A1 (en) * | 2018-06-15 | 2019-12-19 | Pfizer Inc. | Glp-1 receptor agonists and uses thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115667238A (zh) * | 2020-12-25 | 2023-01-31 | 四川海思科制药有限公司 | 一种五并五元环衍生物及其在医药上的应用 |
| CN115667238B (zh) * | 2020-12-25 | 2024-08-23 | 西藏海思科制药有限公司 | 一种五并五元环衍生物及其在医药上的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115697338B (zh) | 2024-08-09 |
| US20230234968A1 (en) | 2023-07-27 |
| WO2021249492A1 (zh) | 2021-12-16 |
| EP4166142A4 (en) | 2024-06-26 |
| EP4166142A1 (en) | 2023-04-19 |
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