CN115666722A - 包封的rna复制子和使用方法 - Google Patents
包封的rna复制子和使用方法 Download PDFInfo
- Publication number
- CN115666722A CN115666722A CN202180038250.2A CN202180038250A CN115666722A CN 115666722 A CN115666722 A CN 115666722A CN 202180038250 A CN202180038250 A CN 202180038250A CN 115666722 A CN115666722 A CN 115666722A
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- Prior art keywords
- certain embodiments
- coding region
- recombinant rna
- rna replicon
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12Y304/23—Aspartic endopeptidases (3.4.23)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063032000P | 2020-05-29 | 2020-05-29 | |
| US63/032,000 | 2020-05-29 | ||
| PCT/US2021/034787 WO2021243172A1 (en) | 2020-05-29 | 2021-05-28 | Encapsulated rna replicons and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115666722A true CN115666722A (zh) | 2023-01-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180038250.2A Pending CN115666722A (zh) | 2020-05-29 | 2021-05-28 | 包封的rna复制子和使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230416308A1 (https=) |
| EP (1) | EP4157456A4 (https=) |
| JP (1) | JP2023528300A (https=) |
| KR (1) | KR20230019450A (https=) |
| CN (1) | CN115666722A (https=) |
| AU (1) | AU2021281357A1 (https=) |
| CA (1) | CA3180557A1 (https=) |
| WO (1) | WO2021243172A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118460614A (zh) * | 2024-07-05 | 2024-08-09 | 凌意(杭州)生物科技有限公司 | 一种腺相关病毒Cap蛋白的表达框 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| AU2023259636A1 (en) * | 2022-04-29 | 2024-10-10 | Elevatebio Technologies, Inc. | Production of rna polynucleotides encoding picornavirus |
| WO2023223183A1 (en) * | 2022-05-16 | 2023-11-23 | Crispr Therapeutics Ag | Picornaviral vectors for gene editing |
| EP4704872A2 (en) * | 2023-05-05 | 2026-03-11 | Mayo Foundation for Medical Education and Research | Methods and materials for treating cancer |
| WO2025072371A2 (en) * | 2023-09-27 | 2025-04-03 | The General Hospital Corporation | Highly active myeloid therapy |
| ES3058740A1 (es) * | 2025-08-01 | 2026-03-12 | Univ Valencia Politecnica | Nanopartícula lipídica, composición farmacéutica y uso de la nanopartícula en el tratamiento del cáncer |
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| US20030040498A1 (en) * | 2001-03-14 | 2003-02-27 | Ansardi David Calvert | Oncolytic RNA replicons |
| US20030077251A1 (en) * | 2001-05-23 | 2003-04-24 | Nicolas Escriou | Replicons derived from positive strand RNA virus genomes useful for the production of heterologous proteins |
| US20100129406A1 (en) * | 2006-09-01 | 2010-05-27 | Anza Therapeutics, Inc. | Holin-enhanced vaccines and reagents, and methods of use thereof |
| JP6396891B2 (ja) * | 2013-04-17 | 2018-09-26 | 新日本製薬株式会社 | 遺伝子改変コクサッキーウイルス |
| MA41506A (fr) * | 2015-02-13 | 2017-12-19 | Takeda Vaccines Inc | Procédés de production de virus pour produire des vaccins |
| AU2018301701A1 (en) * | 2017-07-14 | 2020-02-27 | Elevatebio Technologies, Inc. | Encapsulated polynucleotides and methods of use |
| EP3876951A1 (en) * | 2018-11-06 | 2021-09-15 | Calidi Biotherapeutics, Inc. | Enhanced systems for cell-mediated oncolytic viral therapy |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN118460614A (zh) * | 2024-07-05 | 2024-08-09 | 凌意(杭州)生物科技有限公司 | 一种腺相关病毒Cap蛋白的表达框 |
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