CN1154247A - Cooling throat oral liquor - Google Patents

Abstract

This invented throat refreshing oral liquid is composed of Radix Scutellariae 50-280g, Fructus Forsythiae 100-300g, Rehmannia glutinosa 10-300g, Folium Perillae 10-30g, buffalo horn 50-250g, dandelion 50-200g, Radix Paeoniae Rubra 80-250g, peppermint 10-200g, gypsum 20-500g, Rhizoma Anemarrhenae 50-150g, Spina Gleditsiae 10-300g, licorice 30-150g, and adjuvant to make up 1000 ml oral liquid prepn..

Description

Cool pharynx oral liquid and preparation technology

The present invention relates to the oral agents with heat-clearing and toxic substances removing function and the preparation technology thereof that from natural plants, extract.

Chinese patent application CN1076843 (application number 93100293) has announced a kind of " heat-clearing and detoxifying herb's beverage and preparation method thereof ", be with siccative waters such as GECIGEN, LIANGCIGEN, fujine paederia decoct the water extract; In addition aquatic foods such as Herba Hieracii Umbellati, Kummerowia striata (Thunb.) Schindl, Amaranthus spinosus L. material is added refined salt and mash, squeeze, get press water; It is water-soluble to get brown sugar again, adds siccative water extract and bright material press water, stirs evenly, and sterilization promptly gets the heat-clearing and toxic substances removing beverage.

Purpose of the present invention aims to provide a kind of oral formulations with antipyretic and antidote functions and preparation method thereof.

Cool pharynx oral liquid of the present invention is grouped into by following one-tenth: Radix Scutellariae 50-280g, Fructus Forsythiae 100-300g, Radix Rehmanniae 10-300g, Folium Perillae 10-300g, Cornu Bubali 50-250g, Herba Taraxaci 50-200g, Radix Paeoniae Rubra 80-250g, Herba Menthae 10-200g, Gypsum Fibrosum 20-500g, Rhizoma Anemarrhenae 50-150g, Spina Gleditsiae 10-300g, Radix Glycyrrhizae 30-150g adds adjuvant and makes the 1000ml oral formulations.

The preparation technology of cool pharynx oral liquid of the present invention may further comprise the steps:

(1), the water intaking Cornu Bovis seu Bubali adds 20-40 times of water gaging and decocts, repeated multiple times, collecting decoction, filtration, concentrated;

(2), get Fructus Forsythiae, Herba Menthae, Folium Perillae and add 10-20 times of water gaging, soak, extract volatile oil, residue is standby;

(3), get the residue of Radix Scutellariae, the Radix Rehmanniae, Herba Taraxaci, Radix Paeoniae Rubra, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Spina Gleditsiae, Radix Glycyrrhizae adding step (two), add 10-20 times of water gaging and fry in shallow oil altogether, repeated multiple times is filtered, merging filtrate, concentrate, add ethanol and reach 30-80%, stir to containing the alcohol amount, leave standstill, filter, filtrate recycling ethanol concentrates;

(4), step (), (two), (three) gained extracting solution are mixed, add adjuvant, accents pH value is 5.2-5.8, makes the 1000ml oral formulations, sterilizes, and packing gets product.

Adjuvant of the present invention is suspending agent, antiseptic, solubilizing agent, correctives, water etc., specifically can be respectively agar, sorbitol, tween 80, cyclamate, essence etc.

Cool pharynx oral liquid of the present invention cures mainly wind heat disease and the lung excess of the stomach heat symptom-complex of sore throat, tonsillitis.Disease is seen heating, slight chill or aversion to cold not, and flushing conjunctival congestion, thirst and liking drink, throat is dry and astringent, scorching hot, itch, pain immediately, dysphagia, red swelling of the pharynx, uvula redness, pharynx rear wall follicle hypertrophy, cough, the expectorant Huang is sticky, yellowish urine, dry stool, red tip of the tongue, white and thin fur or BOHUANG, floating and rapid pulse or sliding number.Has heat-clearing and toxic substances removing, cooling blood and removing stasis, detumescence and apocenosis, the effect of dispelling wind sore-throat relieving.Prove that through toxicity test this oral liquid has no side effect, clinical observation adult sore throat (excess-heat disease) 30 examples, 5 days courses of treatment, oral 3 times of every day, the cool pharynx of each 10ml oral liquid, therapeutic outcome: 19 examples of fully recovering account for 63.3%; Produce effects 10 examples account for 33.3%; Effective 1 example accounts for 3.4%.In addition in 30 routine children's's safety testings (that observation has or not is nauseating, vomiting, stomachache, diarrhoea, inappetence and cardio palmus shape) and above-mentioned adult treatment process, all do not find any untoward reaction.Illustrate that this product is effective, safety.

Embodiment:

Raw material is formed: Radix Scutellariae 200g, Fructus Forsythiae 200g, Radix Rehmanniae 200g, Folium Perillae 100g, Cornu Bubali 200g, Herba Taraxaci 133g, Radix Paeoniae Rubra 200g, Herba Menthae 100g, Gypsum Fibrosum 267g, Rhizoma Anemarrhenae 100g, Spina Gleditsiae 200g, Radix Glycyrrhizae 100g.

More than 12 flavor medicines, the Cornu Bubali list is fried in shallow oil, and adds 30 times of water gagings, decocts seven times, the first five time fried in shallow oil 2 hours at every turn, fried in shallow oil 8 hours for back 2 times at every turn, collecting decoction, filtration, filtrate is concentrated into 100ml, leaves standstill, filters, filtrate for later use.Fructus Forsythiae, Herba Menthae, Folium Perillae add 16 times of water gagings, soak half an hour, extract volatile oil, and it is standby to collect volatile oil.Residue and surplus medicine are fried in shallow oil (Radix Scutellariae boiling water feeds intake) altogether and are added 16 times of water gagings, decoct each 0.5 hour three times, filtered while hot, filtrate are concentrated into relative density 1.15 (80 ℃ of surveys), add 95% ethanol and reach 60% to containing the alcohol amount, stir, left standstill 12 hours, filter, filtrate recycling ethanol, being concentrated into relative density is 1.07 (80 ℃ of surveys), and medicinal liquid adds the Cornu Bubali concentrated solution, and adding distil water is to 950ml, transferring PH in 60-80 ℃ is 5.8, add agar 1g, Pyrusussuriensis fine jade 2g is put cold, add volatile oil, tween 80 5ml, cyclamate 15g, apple essence 10ml, be mixed, adding distil water is sub-packed in the 10ml glass ampule to 1000ml again, sterilization, promptly.

Claims (2)

1, a kind of cool pharynx oral liquid is characterized in that being grouped into by following one-tenth: Radix Scutellariae 50-280g, Fructus Forsythiae 100-300g, Radix Rehmanniae 10-300g, Folium Perillae 10-300g, Cornu Bubali 50-250g, Herba Taraxaci 50-200g, Radix Paeoniae Rubra 80-250g, Herba Menthae 10-200g, Gypsum Fibrosum 20-500g, Rhizoma Anemarrhenae 50-150g, Spina Gleditsiae 10-300g, Radix Glycyrrhizae 30-150g adds adjuvant and makes the 1000ml oral formulations.

2, a kind of preparation technology of cool pharynx oral liquid is characterized in that may further comprise the steps:

(1), the water intaking Cornu Bovis seu Bubali adds 20-40 times of water gaging and decocts, repeated multiple times, collecting decoction, filtration, concentrated;

(2), get Fructus Forsythiae, Herba Menthae, Folium Perillae and add 10-20 times of water gaging, soak, extract volatile oil, residue is standby;

(3), get the residue of Radix Scutellariae, the Radix Rehmanniae, Herba Taraxaci, Radix Paeoniae Rubra, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Spina Gleditsiae, Radix Glycyrrhizae adding step (two), add 10-20 times of water gaging and fry in shallow oil altogether, repeated multiple times is filtered, merging filtrate, concentrate, add ethanol and reach 30-80%, stir to containing the alcohol amount, leave standstill, filter, filtrate recycling ethanol concentrates;

(4), step (), (two), (three) gained extracting solution are mixed, adding adjuvant, to transfer pH value be 5.2-5.8, makes the 1000ml oral formulations, sterilization, and packing gets product.