CN105106900A - Chinese herbal preparation for treating small intestinal Crohn's disease - Google Patents
Chinese herbal preparation for treating small intestinal Crohn's disease Download PDFInfo
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Abstract
The invention discloses a Chinese herbal preparation for treating small intestinal Crohn's disease. The Chinese herbal preparation comprises the following raw materials: dark plum, asarum, corydalis tuber, fructus psoraleae, rhizoma zingiberis, coptis chinensis, radix codonopsitis, cortex phellodendri, processed radix aconiti lateralis slices, bletilla striata, Chinese angelica, radix paeoniae alba, herba gynostemmatis pentaphylli, nutmeg, shizandra berry, dried orange peel, radix saposhnikoviae, cinnamomum cassia, carthamus tinctorius, red ginseng, pericarpium zanthoxyli, salvia miltiorrhiza, radix aucklandiae and honey-fried licorice root, and belongs to the field of traditional Chinese medicine invention. The raw materials are cleaned according to different properties of each traditional Chinese medicine, dicing and pre-treating are carried out, mixing is carried out according to a proportion, and preparation is carried out according to a special method, the Chinese herbal preparation has the effects of promoting the circulation of Qi to relieve pain, activating blood circulation, smoothing vessels, tonifying Qi, supporting Yang, and clearing heat-toxin. The Chinese herbal preparation is unique in product combination and preparation method. Clinical trials show that the Chinese herbal preparation is obvious in curative effect, short in treating period, low in price, and free from adverse reactions and toxic or/and side effects, thereby being wide in market application prospect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for small intestinal Crohn disease, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Crohn disease is a kind of agnogenic bowl inflammatory diseases, all can occur, but be apt to occur in terminal ileum and right hemicolon at any position of gastrointestinal.Primary disease and chronic non-specific ulcerative colitis are referred to as inflammatory bowel (IBD).Primary disease clinical manifestation is stomachache, diarrhoea, intestinal obstruction, shows outward with intestinal such as heating, malnutrition.The many delays of the course of disease, recurrent exerbation, not easily effects a radical cure.And small intestinal Crohn disease is the intestinal tract disease occurring in small intestine site.
Present Chinese medicine is thought: small intestinal Crohn disease is become estranged mainly with the logical knot of noxious dampness, stagnation of QI and blood, evil resistance intestinal, mechanism of qi, evil to damage QI and blood be main pathogenesis to poison, the full intestinal wall edema that its peculiar feature is, depth ulcer.
The therapy of salicylic acid or adrenocortical hormone is taked in the treatment of current doctor trained in Western medicine to primary disease more, several cases carries out operative treatment, but the long-term or short time uses these Western medicine to treat, hypertension, edema, Nausea and vomiting, dizziness can be caused, constipation etc. series of side effects symptom, and cause primary affection knock-on increase the weight of the side effect with secondary, patient can be made to produce very large misery, therapeutic process again and again, DeGrain, expense is high, causes larger pressure at heart and ailing pressure to patient.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for small intestinal Crohn disease, it is remarkable that this Chinese medicine preparation has therapeutic effect for treatment small intestinal Crohn disease, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of small intestinal Crohn disease repeatedly.The present invention has that therapeutic effect is remarkable, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
The effect of Chinese medicine of the present invention:
Wherein:
Herba Asari: be aristolochiaceae plant Herba Asari AsarumheterotropoidesFr.Schmidtvar.mandshuricum(Maxim.) the dry herb of Kitag., Seoul Herba Asari AsarumsieboldiiMiq.var.seoulenseNakai or magnificent Herba Asari AsarumsieboldiiMiq..Nature and flavor: pungent, temperature.GUIXIN, lung, kidney channel.Effect: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.Record in " herbal classic ": main cough with dyspnea, headache brain moves, hundred joint contractures, rheumatic arthralgia, dead flesh.Improving eyesight, sharp nine orifices.
Rhizoma Corydalis: be the dry tuber of papaveraceae plant corydalis CorydalisyanhusuoW.T.Wang.Nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Record in " Japan hanako materia medica ": except wind, control gas, warm waist knee joint, broken disease addiction, flutter damage blood stasis, fall tire, and sudden and violent lumbago.
Fructus Psoraleae: be the dry mature fruit of legumes psoraleae PsoraleacorylifoliaL..Nature and flavor: pungent, bitter, temperature.Return kidney, spleen channel.Effect: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.Record in " beautiful Chinese catalpa medicine solution ": warm water and soil, digestion diet, rises and reaches taste, convergence lingering diarrhea, seminal emission, leukorrhagia, drown many, just slide all cards.
Rhizoma Zingiberis: be the dry rhizome of zingiber ZingiberofficinaleRosc..Nature and flavor: pungent, hot.Return spleen, stomach, kidney, the heart, lung meridian.Effect: Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.Record in " detailed outline ": Rhizoma Zingiberis, can draw that blood medicine enters blood system, gas medicine enters edema caused by disorder of QI.Can go again to dislike and support newly, have the meaning of Yin grows while yang is generating.
Rhizoma Coptidis: be the dry rhizome of ranunculaceae plant Rhizoma Coptidis CoptischinensisFranch., Coptis deltoidea C.Y.Cheng et Hsiao CoptisdeltoideaC.Y.ChengetHsiao or Coptis Teeta Wall CoptisteetaWall..Nature and flavor: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.Record in essentials of Matea Medica: control carbuncle skin ulcer scabies, alcoholism, fetal toxicosis.Except infantile malnutrition, kill ascarid.
Radix Codonopsis: be Campanulaceae Radix Codonopsis Codonopsispilosula(Franch.) Nannf., element flower Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) CodonopsispilosulaNannf.var.modesta(Nannf.) dry root of L.T.Shen or radix codonpsis tangshen CodonopsistangshenOliv..Nature and flavor: sweet are flat.Return spleen, lung meridian.Effect: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Cortex Phellodendri: be the dry bark of rutaceae wampee PhellodendronchinenseSchneid. or Cortex Phellodendri PhellodendronamurenseRupr..Nature and flavor: bitter, cold.Return kidney, urinary bladder channel.Effect: heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.Record in " not Lu ": treat frightened gas between skin, red of skin heat, the hot swelling pain of order, aphtha.
Pseudobulbus Bletillae (Rhizoma Bletillae): be orchid Pseudobulbus Bletillae (Rhizoma Bletillae) Bletillastriata(Thunb.) dry tuber of Reichb.f..Nature and flavor: bitter, sweet, puckery, are slightly cold.Return lung, liver, stomach warp.Effect: astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.Record in " property of medicine opinion ": control stagnation of pathogenic heat and do not disappear, flaccidity under main the moon, control Shao-bleb on face, make us flesh and slide.
Radix Angelicae Sinensis: be umbelliferae angelica Angelicasinensis(Oliv.) dry root of Diels.Nature and flavor: sweet, acrid, warm.Return liver, the heart, spleen channel.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.Record in " Japan hanako materia medica ": control a wind cutting, all blood, mend all labor, broken stagnant blood, supports fresh blood and main Disorder addiction.
The Radix Paeoniae Alba: be the dry root of ranunculaceae plant Radix Paeoniae PaeonialactifloraPall..Nature and flavor: bitter, sour, are slightly cold.Return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat." herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Herb Gynostemmae Pentaphylli: be cucurbitaceae genus gynostemma Herb Gynostemmae Pentaphylli Gynostemmapentaphyllum(Thunb.) Makino, is used as medicine with root stock.Nature and flavor: bitter in the mouth; Micro-sweet; Cool in nature, return lung; Spleen; Kidney channel effect: heat clearing away; Tonify deficiency; Removing toxic substances.Main body void is weak; Nephrasthenia emission; Leukopenia; Hyperlipemia; Viral hepatitis; Chronic gastroenteritis; Chronic tracheitis.
Fructus Schisandrae Chinensis: be magnoliaceae schisandra Schisandrachinensis(Turcz.) dry mature fruit of Baill. or schisandra chinensis SchisandrasphenantheraRehd.etWils..Nature and flavor: sour, sweet, temperature.Return lung, the heart, kidney channel.Effect: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange CitrusreticulataBlanco and variety thereof.Nature and flavor: bitter, pungent, temperature.Return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Radix Saposhnikoviae: be umbelliferae Saposhnikovia divaricata Saposhnikoviadivaricata(Turcz.) dry root of Schischk..Nature and flavor: acrid, sweet, warm.Return bladder, liver, spleen channel.Effect: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.Record in " not Lu ": hypochondriac pain, side of body public attention face is gone, and extremity contraction is anxious, convulsion in word milk gold skin ulcer.
Cortex Cinnamomi: be the dry bark of canella Cortex Cinnamomi CinnamomumcassiaPresl.Nature and flavor: pungent, sweet are warm greatly.Return kidney, spleen, the heart, Liver Channel.Effect: mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea." not Lu ": main pained, side of body wind, hypochondriac pain, warm muscle, promotes blood circulation, only tired, perspire.
Flos Carthami: be the dried floral of feverfew Flos Carthami CarthamustinctoriusL..Nature and flavor: pungent, temperature.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache." detailed outline ": invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.
Radix Ginseng Rubra: be the dry root and rhizome of labiate Radix Salviae Miltiorrhizae SalviamiltiorrhizaBunge..Nature and flavor: bitter, are slightly cold.GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.Record in " the southern regions of the Yunnan Province book on Chinese herbal medicine ": reinforcing the heart sedate, calming heart and tranquilizing mind.Control forgetful punching seized with terror, palpitation with fear is insomnia.
The Radix Aucklandiae: be the dry root of feverfew Radix Aucklandiae AucklandialappaDecne..Nature and flavor: pungent, bitter, temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.Effect: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).For stomachache of having loose bowels.Record in " not Lu ": treat that gas is bad, partially cold in flesh; Main QI-insufficiency, sterilization, (controlling) pyrexial malaria, the essence of row medicine.
Radix Glycyrrhizae Preparata: be the Preparation process product of Radix Glycyrrhizae.Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Fructus Mume: be rose department plant plum Prunusmume(Sieh.) the dry almost ripe fruit of Sieb.etZucc..Nature and flavor: sour, puckery are flat.Return liver, spleen, lung, large intestine channel.Effect: astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.Record in " herbal classic ": the main therapeutic method to keep the adverse QI flowing downwards, heat extraction stuffy sensation with restlessness, feels at ease, limb pain, hemiplegia meciless, dead flesh, removes blue or green melanotic nevus, dislikes meat.
Radix Aconiti Lateralis Preparata: be the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. AconitumcarmichaeliDebx..Nature and flavor: pungent, sweet are warm greatly; Poisonous.GUIXIN, kidney, spleen channel.Effect: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.Record in " herbal classic ": main air is trembled with fear cough with dyspnea pathogen, warming middle-JIAO, and incised wound ， Po Disorder heavily fortified point gathers, abdominal mass due to blood stasis, Han Shi Wei lame, contracture gonalgia, can not go step.
Semen Myristicae: be the dry kernel of Myristicaceae Nutmeg Vegetable meat Fructus Amomi Rotundus MyristicafragransHoutt..Nature and flavor: pungent, temperature.Return spleen, stomach, large intestine channel.Effect: warming middle-JIAO to promote flow of QI, relieving diarrhea with astringents.For Deficiency and coldness of spleen and stomach, incessant chronic diarrhea, abdominal distention, lack of appetite is vomitted.Record in " Kaibao Bencao ": warming middle-JIAO, control accumulation of pathogenic cold trusted subordinate distending pain, cholera attacked by pestiferous factors, spitting saliva, cold air, help digestion stopping leak, and children's's breast suddenly.
Fructus Zanthoxyli: for the dry mature skin (Pericarpium Zanthoxyli) of rutaceae Pericarpium Zanthoxyli and seed (Semen zanthoxyli) are used as medicine.Nature and flavor: pungent, temperature.Return spleen, stomach, kidney channel.Effect: warming middle-JIAO to relieve pain, killing parasites for relieving itching.For coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.Record in " herbal classic ": main air pathogen, warming middle-JIAO, except arthralgia due to cold, hard tooth is sent out, improving eyesight.Main pathogen cough with dyspnea, warming middle-JIAO, by the dead flesh of joint skin, arthralgia due to cold-dampnes, the therapeutic method to keep the adverse QI flowing downwards.
Side's solution of the present invention is: Herba Asari expelling wind and cold, warming the lung to resolve fluid-retention, Rhizoma Corydalis is invigorated blood circulation promoting the circulation of QI, and Radix Saposhnikoviae is expellingged wind and relieving convulsion, Cortex Cinnamomi dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow, Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, Radix Ginseng Rubra stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, Radix Aucklandiae promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, Chinese angelica blood supplementing is invigorated blood circulation, loosening bowel to relieve constipation, the pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, nourishing blood for regulating menstruation, above nine taste medicines, as monarch drug in side, are all returned lung meridian, are had the effect of promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis.Chinese medicine is thought, primary disease main symptom leads to knot, stagnation of QI and blood with noxious dampness, heresy hinders intestinal, mechanism of qi is become estranged, the evil QI and blood of damaging of poison for main pathogenesis, and causes primary disease.So promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis are the bases for the treatment of small intestinal Crohn disease, above nine taste medicines are monarch drug, and first fundamentally promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis makes disease obtain basic control.Fructus Psoraleae warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI antidiarrheal, Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, Radix Codonopsis invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, Radix Aconiti Lateralis Preparata mend fire supporing yang, dehumidify by wind, Semen Myristicae warming middle-JIAO to promote flow of QI, relieving diarrhea with astringents, astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of Fructus Schisandrae Chinensis convergence, ministerial drug in the above Six-element medicine side of being, the endogenous cause of ill of primary disease is internal body disorder of movement of QI, and YANG QI deficiency causes exopathogen invade and cause.As ministerial drug, auxiliary monarch drug better exercises effect of promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis on the one hand; Another aspect has benefiting qi and supporting yang as ministerial drug, effect of promoting the production of body fluid of promoting blood circulation.Fructus Mume astringe the lung astringing intestine to stop diarrhea, promote the production of body fluid relieving colic caused by ascaris, Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication, Cortex Phellodendri heat clearing and damp drying, detoxification sore treatment, Pseudobulbus Bletillae (Rhizoma Bletillae) astringing to arrest bleeding, detumescence and promoting granulation, Herb Gynostemmae Pentaphylli heat clearing away tonify deficiency, dampness are detoxified, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, Fructus Zanthoxyli warming middle-JIAO to relieve pain, killing parasites for relieving itching, above seven flavor medicine is classified as adjuvant drug, the inducement of small intestinal Crohn disease is caused from pathology treatment, the promoting the circulation of QI to relieve pain of the monarch and his subjects two medicine, effect of promoting blood circulation to remove blood stasis can be promoted as adjuvant drug, body benefiting qi and supporting yang, the effect of promoting the production of body fluid of promoting blood circulation can be promoted by using corrigent the monarch and his subjects two medicine again.Simultaneously as adjuvant drug, also there is effect of self heat-clearing and toxic substances removing, dampness pain relieving.Radix Glycyrrhizae Preparata makes medicine as in side, and have the effect of coordinating the actions of various ingredients in a prescription, mediation flavour of a drug, all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of promoting the circulation of QI to relieve pain, blood circulation and channel invigorating benefiting qi and supporting yang, heat-clearing and toxic substances removing, can effectively treat small intestinal Crohn disease.
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, be rich in aminoacid and have more than 17 kinds, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus.Above nutritional labeling is all needed by human material, effectively can strengthen body immunity.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Fructus Mume 28-32 part, Herba Asari 4-8 part, Rhizoma Corydalis 13-17 part, Fructus Psoraleae 16-20 part, Rhizoma Zingiberis 8-12 part, Rhizoma Coptidis 8-12 part, Radix Codonopsis 13-17 part, Cortex Phellodendri 10-14 part, Radix Aconiti Lateralis Preparata 8-12 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-14 part, Radix Angelicae Sinensis 16-20 part, Radix Paeoniae Alba 13-17 part, Herb Gynostemmae Pentaphylli 13-17 part, Semen Myristicae 7-11 part, Fructus Schisandrae Chinensis 10-14 part, Pericarpium Citri Reticulatae 10-14 part, Radix Saposhnikoviae 10-14 part, Cortex Cinnamomi 8-12 part, Flos Carthami 7-11 part, Radix Ginseng Rubra 8-12 part, Fructus Zanthoxyli 4-8 part, Radix Aucklandiae 10-14 part, Radix Glycyrrhizae Preparata 8-12 part.
Wherein be preferably: Fructus Mume 30 parts, Herba Asari 6 parts, Rhizoma Corydalis 15 parts, Fructus Psoraleae 18 parts, Rhizoma Zingiberis 10 parts, Rhizoma Coptidis 10 parts, Radix Codonopsis 15 parts, Cortex Phellodendri 12 parts, Radix Aconiti Lateralis Preparata 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Radix Angelicae Sinensis 18 parts, the Radix Paeoniae Alba 15 parts, Herb Gynostemmae Pentaphylli 15 parts, Semen Myristicae 9 parts, Fructus Schisandrae Chinensis 12 parts, Pericarpium Citri Reticulatae 12 parts, Radix Saposhnikoviae 12 parts, Cortex Cinnamomi 10 parts, 9 parts, Flos Carthami, Radix Ginseng Rubra 10 parts, Fructus Zanthoxyli 6 parts, the Radix Aucklandiae 12 parts, Radix Glycyrrhizae Preparata 10 parts.
A kind of preparation method of the Chinese medicine preparation for small intestinal Crohn disease is as follows:
Step one: by weight of the present invention, gets Radix Aconiti Lateralis Preparata and puts into container, adds the water of 3 times of volumes, and intense fire infusion is after 40-50 minute, and lard speech with literary allusions fiery infusion 10-20 minute, filter liquor, three times repeatedly, and merging filtrate is for subsequent use;
Step 2: by weight proportion of the present invention, get Rhizoma Corydalis, Rhizoma Zingiberis, Rhizoma Coptidis, Radix Codonopsis, Cortex Phellodendri, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Paeoniae Alba, Herb Gynostemmae Pentaphylli, Semen Myristicae, Radix Saposhnikoviae, Cortex Cinnamomi, Radix Ginseng Rubra, Fructus Zanthoxyli medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Herba Asari, Fructus Psoraleae, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Flos Carthami, the Radix Aucklandiae, Radix Glycyrrhizae Preparata and respectively with Fructus Mume, Fructus Schisandrae Chinensis that bundle ties, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use;
Step 3: by step one, two gained filtrates mixing, stir evenly, is undertaken medicine soup concentrated adding ethanol, place precipitation, filter, abandon precipitation, gained concentration of liquid medicine is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment, by air-dry for thick paste pulverizing by filtrate recycling ethanol, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, every bag containing effective ingredient 2g, both the pill for the treatment of small intestinal Crohn disease of the present invention.
Using method of the present invention: get pill, takes in one hour after meal by each half bag, every day three times.
Medicine of the present invention has the effect of promoting the circulation of QI to relieve pain, blood circulation and channel invigorating benefiting qi and supporting yang, heat-clearing and toxic substances removing, and good analgesic effect, cheap, have no side effect, easy to use, the mode that this Chinese medicine preparation adopts is treated and can be reduced the injury of Western medicine to patient body, alleviate the slight illness of patient, according to clinical 240 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 82.5%, two the total effective rate course for the treatment of 95%.
Detailed description of the invention
Embodiment one: Fructus Mume 30 parts, Herba Asari 6 parts, Rhizoma Corydalis 15 parts, Fructus Psoraleae 18 parts, Rhizoma Zingiberis 10 parts, Rhizoma Coptidis 10 parts, Radix Codonopsis 15 parts, Cortex Phellodendri 12 parts, Radix Aconiti Lateralis Preparata 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Radix Angelicae Sinensis 18 parts, the Radix Paeoniae Alba 15 parts, Herb Gynostemmae Pentaphylli 15 parts, Semen Myristicae 9 parts, Fructus Schisandrae Chinensis 12 parts, Pericarpium Citri Reticulatae 12 parts, Radix Saposhnikoviae 12 parts, Cortex Cinnamomi 10 parts, 9 parts, Flos Carthami, Radix Ginseng Rubra 10 parts, Fructus Zanthoxyli 6 parts, the Radix Aucklandiae 12 parts, Radix Glycyrrhizae Preparata 10 parts.
Embodiment two: Fructus Mume 31 parts, Herba Asari 5 parts, Rhizoma Corydalis 14 parts, Fructus Psoraleae 17 parts, Rhizoma Zingiberis 10 parts, Rhizoma Coptidis 11 parts, Radix Codonopsis 14 parts, Cortex Phellodendri 12 parts, Radix Aconiti Lateralis Preparata 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Radix Angelicae Sinensis 17 parts, the Radix Paeoniae Alba 14 parts, Herb Gynostemmae Pentaphylli 14 parts, Semen Myristicae 9 parts, Fructus Schisandrae Chinensis 12 parts, Pericarpium Citri Reticulatae 12 parts, Radix Saposhnikoviae 13 parts, Cortex Cinnamomi 11 parts, 9 parts, Flos Carthami, Radix Ginseng Rubra 10 parts, Fructus Zanthoxyli 6 parts, the Radix Aucklandiae 13 parts, Radix Glycyrrhizae Preparata 11 parts.
Embodiment three: Fructus Mume 30 parts, Herba Asari 7 parts, Rhizoma Corydalis 14 parts, Fructus Psoraleae 17 parts, Rhizoma Zingiberis 10 parts, Rhizoma Coptidis 10 parts, Radix Codonopsis 15 parts, Cortex Phellodendri 13 parts, Radix Aconiti Lateralis Preparata 11 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 11 parts, Radix Angelicae Sinensis 17 parts, the Radix Paeoniae Alba 14 parts, Herb Gynostemmae Pentaphylli 14 parts, Semen Myristicae 8 parts, Fructus Schisandrae Chinensis 12 parts, Pericarpium Citri Reticulatae 12 parts, Radix Saposhnikoviae 11 parts, Cortex Cinnamomi 11 parts, 7 parts, Flos Carthami, Radix Ginseng Rubra 10 parts, Fructus Zanthoxyli 7 parts, the Radix Aucklandiae 11 parts, Radix Glycyrrhizae Preparata 11 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 240 example for medical treatment, patient is divided at random observation group and each 120 examples of matched group, wherein male 140 example, women 100 example, M-F 1.4:1, max age 55 years old, minimal ages 25 years old, the course of disease several months to several years is not etc.Every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, diagnostic criteria
1, noncontinuity or regional intestinal pathological changes;
2, intestinal mucosa shows in cobble sample of paving the way or has vertical shape ulcer;
3, holostrome imflammatory bowel pathological changes, with lump or narrow;
4, the non-cheese granuloma of sarcoidosis sample;
5, dehiscence furrow or fistula;
6, anus pathological changes: intractable ulcer, anal fistula or anal fissure.
Make a definite diagnosis: possess 1,2,3 any one added in 4,5,6.
Three, Therapeutic Method:
1, observation group is according to Medications Example one of the present invention, and weighting raw materials, by the treatment of invention implementation method, is got pill, each half bag, taken in one hour after meal, every day three times.It within 7 days, is a course for the treatment of.
2, matched group adopts conventional western medicine adrenocortical hormones in treating, within 7 days, is a course for the treatment of.
Four, efficacy assessment standard:
1, cure: small intestinal and anus all clinical symptoms all disappear, functional rehabilitation is normal, not recurrence in half a year.
2, take a turn for the better: small intestinal and anus all clinical symptoms disappear substantially, and function recovers normal substantially, in half a year, occur recurrence once in a while.
3, invalid: above-mentioned diagnostic symptom is all not improved or instead adds severe one.
Five, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of
Wherein: total effective rate=cure rate+improvement rate
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness on treatment small intestinal Crohn disease, effectively can improve the cure rate for the treatment of, Be very effective, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.
Model case and curative effect:
Case one, patient Wang, man, 36 years old, people from Qingdao City, came here and goes to a doctor on January 20th, 2012.Patient gives an oral account the appearance fever phenomenon without inducement, the highest 39 degree, and night body temperature is down to normally automatically, with cough, pharyngalgia, and abdominal discomfort, rare fulminant leucorrhagia with yellowish discharge blood of defecating.Microscopy shows: distal small intestine and ileal mucous membrane have ulcer, and there is white fur on surface, have hematoma.Be diagnosed as small intestinal Crohn disease.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, after two courses for the treatment of of treatment, effect is very good, and Small Intestine is recovered completely or substantially, and Effect of follow-up visit by telephone does not recur for 1 year.
Case two, patient Lee, man, 42 years old, people from Linyi, Shandong.Come here on May 14th, 2011 to go to a doctor, before one week, because there is paroxysmal epigastrium angor after drinking too much, spontaneous remission.There is epigastrium angor because drinking in today, in paroxysmal, companion's Nausea and vomiting, vomitus is gastric content again.Small intestinal ulcer, matter is hard, and bottom is coated to white fur, sees normal mucosa between ulcer, and mucous membrane of small intestine many places lamellar is congested, rotten to the corn, is diagnosed as small intestinal Crohn disease.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, after two courses for the treatment of of treatment, effect is very good, and Small Intestine is recovered completely, and Effect of follow-up visit by telephone does not recur half a year.
Claims (4)
1. the Chinese medicine preparation for small intestinal Crohn disease, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Fructus Mume 28-32 part, Herba Asari 4-8 part, Rhizoma Corydalis 13-17 part, Fructus Psoraleae 16-20 part, Rhizoma Zingiberis 8-12 part, Rhizoma Coptidis 8-12 part, Radix Codonopsis 13-17 part, Cortex Phellodendri 10-14 part, Radix Aconiti Lateralis Preparata 8-12 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-14 part, Radix Angelicae Sinensis 16-20 part, Radix Paeoniae Alba 13-17 part, Herb Gynostemmae Pentaphylli 13-17 part, Semen Myristicae 7-11 part, Fructus Schisandrae Chinensis 10-14 part, Pericarpium Citri Reticulatae 10-14 part, Radix Saposhnikoviae 10-14 part, Cortex Cinnamomi 8-12 part, Flos Carthami 7-11 part, Radix Ginseng Rubra 8-12 part, Fructus Zanthoxyli 4-8 part, Radix Aucklandiae 10-14 part, Radix Glycyrrhizae Preparata 8-12 part.
2. the Chinese medicine preparation for small intestinal Crohn disease according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Fructus Mume 30 parts, Herba Asari 6 parts, Rhizoma Corydalis 15 parts, Fructus Psoraleae 18 parts, Rhizoma Zingiberis 10 parts, Rhizoma Coptidis 10 parts, Radix Codonopsis 15 parts, Cortex Phellodendri 12 parts, Radix Aconiti Lateralis Preparata 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Radix Angelicae Sinensis 18 parts, the Radix Paeoniae Alba 15 parts, Herb Gynostemmae Pentaphylli 15 parts, Semen Myristicae 9 parts, Fructus Schisandrae Chinensis 12 parts, Pericarpium Citri Reticulatae 12 parts, Radix Saposhnikoviae 12 parts, Cortex Cinnamomi 10 parts, 9 parts, Flos Carthami, Radix Ginseng Rubra 10 parts, Fructus Zanthoxyli 6 parts, the Radix Aucklandiae 12 parts, Radix Glycyrrhizae Preparata 10 parts.
3. the Chinese medicine preparation for small intestinal Crohn disease according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is pill.
4. the preparation method for the Chinese medicine preparation of small intestinal Crohn disease, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, gets Radix Aconiti Lateralis Preparata and puts into container, adds the water of 3 times of volumes, intense fire infusion is after 40-50 minute, lard speech with literary allusions fiery infusion 10-20 minute, filter liquor, three times repeatedly, merging filtrate, for subsequent use; Step 2: by weight proportion of the present invention, get Rhizoma Corydalis, Rhizoma Zingiberis, Rhizoma Coptidis, Radix Codonopsis, Cortex Phellodendri, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Paeoniae Alba, Herb Gynostemmae Pentaphylli, Semen Myristicae, Radix Saposhnikoviae, Cortex Cinnamomi, Radix Ginseng Rubra, Fructus Zanthoxyli medical material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Herba Asari, Fructus Psoraleae, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Flos Carthami, the Radix Aucklandiae, Radix Glycyrrhizae Preparata and respectively with Fructus Mume, Fructus Schisandrae Chinensis that bundle ties, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use; Step 3: by step one, two gained filtrates mixing, stir evenly, is undertaken medicine soup concentrated adding ethanol, place precipitation, filter, abandon precipitation, gained concentration of liquid medicine is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment, by air-dry for thick paste pulverizing by filtrate recycling ethanol, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, every bag containing effective ingredient 2g, both the pill for the treatment of small intestinal Crohn disease of the present invention.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113134065A (en) * | 2021-06-07 | 2021-07-20 | 河南大学淮河医院 | Traditional Chinese medicine decoction for treating Crohn's disease |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324350A (en) * | 2014-11-19 | 2015-02-04 | 厉岩 | Traditional Chinese medicine composition for chronic colitis and preparation method of traditional Chinese medicine composition |
| CN104740583A (en) * | 2015-04-13 | 2015-07-01 | 李庆云 | Traditional Chinese medicine preparation for relieving Crohn's disease and preparation method for traditional Chinese medicine preparation |
| CN104826050A (en) * | 2015-04-28 | 2015-08-12 | 广西大学 | Traditional Chinese medicine composition for treating chronic ulcerative colitis and preparation method thereof |
-
2015
- 2015-09-22 CN CN201510605739.XA patent/CN105106900A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324350A (en) * | 2014-11-19 | 2015-02-04 | 厉岩 | Traditional Chinese medicine composition for chronic colitis and preparation method of traditional Chinese medicine composition |
| CN104740583A (en) * | 2015-04-13 | 2015-07-01 | 李庆云 | Traditional Chinese medicine preparation for relieving Crohn's disease and preparation method for traditional Chinese medicine preparation |
| CN104826050A (en) * | 2015-04-28 | 2015-08-12 | 广西大学 | Traditional Chinese medicine composition for treating chronic ulcerative colitis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘亮: "乌梅丸煎剂治疗克罗恩病42例的体会", 《现代中医药》 * |
| 李峰主编: "《中药商品学》", 31 August 2014, 中国医药科技出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113134065A (en) * | 2021-06-07 | 2021-07-20 | 河南大学淮河医院 | Traditional Chinese medicine decoction for treating Crohn's disease |
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Application publication date: 20151202 |