CN115397440A - 用半抗原标记细胞刺激嵌合抗原受体t细胞的方法和组合物 - Google Patents

用半抗原标记细胞刺激嵌合抗原受体t细胞的方法和组合物 Download PDF

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CN115397440A
CN115397440A CN202180019063.XA CN202180019063A CN115397440A CN 115397440 A CN115397440 A CN 115397440A CN 202180019063 A CN202180019063 A CN 202180019063A CN 115397440 A CN115397440 A CN 115397440A
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cells
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car
hapten
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迈克尔·C·詹森
詹姆斯·F·马泰伊
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Seattle Childrens Hospital
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    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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CN202180019063.XA 2020-02-04 2021-02-02 用半抗原标记细胞刺激嵌合抗原受体t细胞的方法和组合物 Pending CN115397440A (zh)

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US202062969917P 2020-02-04 2020-02-04
US62/969,917 2020-02-04
PCT/US2021/016194 WO2021158534A1 (en) 2020-02-04 2021-02-02 Methods and compositions for stimulation of chimeric antigen receptor t cells with hapten labelled cells

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US (1) US20230172981A1 (https=)
EP (1) EP4100026A4 (https=)
JP (1) JP7744914B2 (https=)
KR (1) KR20220164474A (https=)
CN (1) CN115397440A (https=)
AU (1) AU2021216554A1 (https=)
CA (1) CA3169804A1 (https=)
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WO (1) WO2021158534A1 (https=)

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EP2934532B1 (en) 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
JP7282521B2 (ja) 2016-04-08 2023-05-29 パーデュー・リサーチ・ファウンデイション Car t細胞療法のための方法および組成物
JP7178355B2 (ja) 2017-02-28 2022-11-25 エンドサイト・インコーポレイテッド Car t細胞療法のための組成物および方法
JP7549303B2 (ja) 2018-01-22 2024-09-11 エンドサイト・インコーポレイテッド Car t細胞の使用方法
SG11202007426XA (en) * 2018-02-06 2020-09-29 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
CN112105382A (zh) 2018-02-23 2020-12-18 恩多塞特公司 用于car t细胞疗法的顺序方法
AU2021217003A1 (en) 2020-02-04 2022-09-15 Seattle Children's Hospital (dba Seattle Children's Research Institute) Anti-dinitrophenol chimeric antigen receptors
WO2023178073A2 (en) * 2022-03-15 2023-09-21 Celledit Llc Use of antigen presenting cells to enhance car-t cell therapy
WO2024206913A2 (en) * 2023-03-31 2024-10-03 Northwestern University Compositions for antigen-specific immune cell activation
WO2024251866A1 (en) * 2023-06-06 2024-12-12 Danmarks Tekniske Universitet A synthetic cellular advanced signal adapter (scasa) system

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US20020004052A1 (en) * 1990-05-08 2002-01-10 David Berd Composition comprising a tumor cell extract and method of using the composition
KR102376244B1 (ko) * 2014-12-24 2022-03-21 오토러스 리미티드 세포
WO2017075440A1 (en) * 2015-10-30 2017-05-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Targeted cancer therapy
CN115404196A (zh) 2016-07-13 2022-11-29 哈佛学院院长等 抗原呈递细胞模拟支架及其制备和使用方法
US10617720B2 (en) * 2016-10-20 2020-04-14 Miltenyi Biotech, GmbH Chimeric antigen receptor specific for tumor cells
EP3336107A1 (en) * 2016-12-15 2018-06-20 Miltenyi Biotec GmbH Immune cells expressing an antigen binding receptor and a chimeric costimulatory receptor
US11590214B2 (en) * 2016-12-21 2023-02-28 Danmarks Tekniskte Universitet Antigen presenting scaffolds for immune-cell manipulation
CN110612119B (zh) * 2017-02-07 2024-10-29 西雅图儿童医院(Dba西雅图儿童研究所) 磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂
WO2019060425A1 (en) 2017-09-19 2019-03-28 Massachusetts Institute Of Technology COMPOSITIONS FOR CHIMERIC ANTIGENIC RECEPTOR T CELL THERAPY AND USES THEREOF
MX2020004185A (es) * 2017-09-27 2021-01-08 Univ Southern California Nuevas plataformas para coestimulacion, nuevos diseños car y otras mejoras para terapia celular adoptiva.
SG11202007426XA (en) 2018-02-06 2020-09-29 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
KR20210074274A (ko) * 2018-08-06 2021-06-21 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 합텐 표지된 세포로의 키메라 항원 수용체 t 세포의 자극을 위한 방법 및 조성물

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JP2023513156A (ja) 2023-03-30
IL295074A (en) 2022-09-01
KR20220164474A (ko) 2022-12-13
JP7744914B2 (ja) 2025-09-26
US20230172981A1 (en) 2023-06-08
WO2021158534A1 (en) 2021-08-12
CA3169804A1 (en) 2021-08-12
EP4100026A1 (en) 2022-12-14
AU2021216554A1 (en) 2022-09-15
EP4100026A4 (en) 2024-03-06

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