CN115279890A - 用于生产3-羟基己二酸和/或α-氢化己二烯二酸的基因修饰微生物以及该化学品的制造方法 - Google Patents

用于生产3-羟基己二酸和/或α-氢化己二烯二酸的基因修饰微生物以及该化学品的制造方法 Download PDF

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CN115279890A
CN115279890A CN202180019886.2A CN202180019886A CN115279890A CN 115279890 A CN115279890 A CN 115279890A CN 202180019886 A CN202180019886 A CN 202180019886A CN 115279890 A CN115279890 A CN 115279890A
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矶部匡平
河村健司
山田胜成
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Toray Industries Inc
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Toray Industries Inc
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12P7/42—Hydroxy-carboxylic acids
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
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    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/425—Serratia

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  • Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202180019886.2A 2020-03-18 2021-03-17 用于生产3-羟基己二酸和/或α-氢化己二烯二酸的基因修饰微生物以及该化学品的制造方法 Pending CN115279890A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-047328 2020-03-18
JP2020047328 2020-03-18
PCT/JP2021/010871 WO2021187533A1 (ja) 2020-03-18 2021-03-17 ３－ヒドロキシアジピン酸および／またはα－ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

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CN115279890A true CN115279890A (zh) 2022-11-01

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CN202180019886.2A Pending CN115279890A (zh) 2020-03-18 2021-03-17 用于生产3-羟基己二酸和/或α-氢化己二烯二酸的基因修饰微生物以及该化学品的制造方法

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US (1) US12577592B2 (https=)
JP (1) JP7784060B2 (https=)
CN (1) CN115279890A (https=)
WO (1) WO2021187533A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111386339A (zh) * 2017-11-30 2020-07-07 东丽株式会社 用于生产3-羟基己二酸、α-氢化己二烯二酸及/或己二酸的基因修饰微生物以及该化学产品的制造方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023182322A1 (ja) 2022-03-23 2023-09-28 東レ株式会社 ３－ヒドロキシアジピン酸および／または３－オキソアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
WO2025063258A1 (ja) * 2023-09-21 2025-03-27 東レ株式会社 α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160130618A1 (en) * 2013-07-09 2016-05-12 Ajinomoto Co., Inc. Method for Manufacturing Useful Substance
CN109154008A (zh) * 2016-05-31 2019-01-04 东丽株式会社 3-羟基己二酸的制造方法
CN109196107A (zh) * 2016-05-31 2019-01-11 东丽株式会社 α-氢化己二烯二酸的制造方法
WO2019107516A1 (ja) * 2017-11-30 2019-06-06 東レ株式会社 ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3309258B1 (en) * 2015-06-10 2020-06-03 Toray Industries, Inc. Method for producing 3-hydroxyadipic acid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160130618A1 (en) * 2013-07-09 2016-05-12 Ajinomoto Co., Inc. Method for Manufacturing Useful Substance
CN109154008A (zh) * 2016-05-31 2019-01-04 东丽株式会社 3-羟基己二酸的制造方法
CN109196107A (zh) * 2016-05-31 2019-01-11 东丽株式会社 α-氢化己二烯二酸的制造方法
WO2019107516A1 (ja) * 2017-11-30 2019-06-06 東レ株式会社 ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KEITA FUKUI等: "Escherichia coli yjjPB genes encode a succinate transporter important for succinate production", 《BIOSCI BIOTECHNOL BIOCHEM》, vol. 81, no. 9, pages 1837 - 1844 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111386339A (zh) * 2017-11-30 2020-07-07 东丽株式会社 用于生产3-羟基己二酸、α-氢化己二烯二酸及/或己二酸的基因修饰微生物以及该化学产品的制造方法
CN111386339B (zh) * 2017-11-30 2024-05-10 东丽株式会社 用于生产3-羟基己二酸、α-氢化己二烯二酸及/或己二酸的基因修饰微生物以及该化学产品的制造方法

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US12577592B2 (en) 2026-03-17
JPWO2021187533A1 (https=) 2021-09-23
US20230101086A1 (en) 2023-03-30
WO2021187533A1 (ja) 2021-09-23
JP7784060B2 (ja) 2025-12-11

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