CN115006473B - Traditional Chinese medicine wine for treating arthralgia and preparation method thereof - Google Patents
Traditional Chinese medicine wine for treating arthralgia and preparation method thereof Download PDFInfo
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- CN115006473B CN115006473B CN202210417026.0A CN202210417026A CN115006473B CN 115006473 B CN115006473 B CN 115006473B CN 202210417026 A CN202210417026 A CN 202210417026A CN 115006473 B CN115006473 B CN 115006473B
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Abstract
The application provides traditional Chinese medicine wine for treating arthralgia and a preparation method thereof, and relates to the field of traditional Chinese medicines. A traditional Chinese medicine wine for treating arthralgia, comprising: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of lycopodium clavatum, 120-300 parts of fructus liquidambaris, 120-300 parts of mistletoe, 120-300 parts of nux vomica, 120-300 parts of radix aconiti, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of radix philippine fleeceflower root and 80-250 parts of holly bark. The medicated liquor has rapid drug action and strong permeability, can rapidly permeate into the affected part of a patient, and has the functions of removing toxic substances, removing blood stasis, diminishing inflammation, sterilizing, dispelling pathogenic wind, removing dampness, strengthening tendons and bones, relieving swelling and pain, and repairing damaged tissues and cells.
Description
Technical Field
The application relates to the field of traditional Chinese medicines, in particular to traditional Chinese medicine wine for treating arthralgia and a preparation method thereof.
Background
Most people have more rheumatic arthralgia and arthralgia caused by excessive strain, cervical spondylosis presses nerves, blood circulation is not smooth, qi and blood are not smooth and other body problems, and especially the middle-aged and elderly friends suffer from cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, osteoarthropathy, and more from rheumatic arthritis, rheumatic arthropathy, synovitis, traumatic injury, joint neuralgia and other body pain diseases. In addition, the modernization process is accelerated, the intelligent mobile phone is popularized, and many young people play mobile phones and computers for a long time at low head, so that joint diseases, especially cervical vertebra and lumbar vertebra, are caused to occur to different degrees at the cervical vertebra and lumbar vertebra, and various joint diseases develop gradually from the previous middle-aged and old people.
The traditional Chinese medicine considers that most joint pain diseases are caused by blockage of channels and collaterals, attack of pathogenic wind, cold, damp and heat, deficiency and obstruction of qi and blood, soft tissue damage and other reasons. The meridians connect with the skin and muscle striae externally and the five zang organs and the six g organs internally to connect with the parts of the whole body, so that the human body becomes an organic unity. At present, the treatment method for the arthralgia is diversified and mainly comprises the treatment of medicine analgesia, physical treatment, traditional physiotherapy and traditional Chinese medicine. If hormone is used for treatment, the toxic and side effects are large, and serious complications such as central obesity, hirsutism, gastrorrhagia and the like are easy to occur after long-term administration. The traditional Chinese medicine has no toxic or side effect, can achieve the effect of treating both principal and secondary aspect of disease, is popular with patients, and has a certain effect by taking oral medicinal liquor or decoction, external medicinal liquor, external plaster and the like. At present, the medicines for treating the joint diseases are most in plaster form on the market, the plaster has great side effects on the treatment of the joint diseases, the effect is not obvious, and the plaster has great damage to the skin of a human body. The medicated liquor has effects in promoting local blood circulation, relieving muscle tension spasm, improving oxygen supply to local tissue, promoting metabolism, and relieving inflammation. Therefore, it is very important to develop a traditional Chinese medicine composition which has quick response, simple and safe use, no irritation to skin, no side effect to human body and can effectively treat various arthralgia.
Disclosure of Invention
The application aims to provide a traditional Chinese medicine wine for treating arthralgia, which has the functions of drawing out toxin, removing blood stasis, diminishing inflammation, sterilizing, dispelling wind, removing dampness, strengthening tendons and bones, relieving swelling and pain and repairing damaged tissues and cells.
The application also aims to provide a preparation method of the traditional Chinese medicine wine for treating arthralgia, which can effectively extract the effective components in the medicinal materials, so that the medicinal materials exert the maximum medicinal effect.
The application solves the technical problems by adopting the following technical scheme.
On one hand, the embodiment of the application provides traditional Chinese medicine wine for treating arthralgia, which comprises white wine and the following raw materials in parts by weight: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of lycopodium clavatum, 120-300 parts of fructus liquidambaris, 120-300 parts of mistletoe, 120-300 parts of nux vomica, 120-300 parts of radix aconiti, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of radix philippine fleeceflower root and 80-250 parts of holly bark.
On the other hand, the embodiment of the application provides a preparation method of traditional Chinese medicine wine for treating arthralgia, which comprises the following steps:
pretreatment of medicinal materials: parching semen Strychni with sand; soaking radix Aconiti in water, taking out when the taste has spicy taste, mixing sand-parched semen Strychni and soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, semen Strychni, radix Wikstroemia indica, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
preparation of medicinal liquor: mixing the dried raw materials with the Chinese liquor, sealing, soaking, filtering to remove impurities, distilling the filtered liquid medicine to obtain extractive solution, extracting the extractive solution, and sealing and storing to obtain the medicated liquor.
Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:
the traditional Chinese medicine composition is prepared according to external treatment of internal diseases in the traditional Chinese medicine, and the traditional Chinese medicine considers that the traditional Chinese medicine composition is no matter wind-cold-damp-heat; or traumatic injury; swelling pain due to qi stagnation and blood stasis is caused by obstruction of qi and blood meridians. In the traditional Chinese medicine composition, the moxa has the effects of dispelling wind and removing dampness, clearing and activating the channels and collaterals, and reducing swelling and resolving masses, and is a monarch drug because the moxa is purely yang and can penetrate all channels for removing hundred diseases by moxibustion fire; the elder, the garden balsam stem, the suberect spatholobus stem and the common clubmoss herb are matched with each other, can dispel wind and remove dampness, relax tendons and activate blood, reduce swelling and relieve pain, are ministerial drugs, can be used for treating joint ache by matching with monarch drugs, and are disadvantageous in flexion and extension; fructus Lipuidambaris, herba Taxilli, semen Strychni, radix Aconiti and Indian Stringbush are used as adjuvant drugs, wherein the fructus Lipuidambaris and the Indian Stringbush are matched with each other, and can clear away heat and toxic materials, promote diuresis and promote menstruation; the nux vomica and the common monkshood mother root are matched with each other, so that the Chinese medicinal composition can remove meridian obstruction, relieve pain, dissipate stagnation and reduce swelling; loranthus mulberry mistletoe can tonify liver and kidney and strengthen tendons and bones; can be used in combination with monarch drug for treating rheumatalgia, soreness of waist and knees, weakness of tendons and bones, etc.; 37. the radix notoginseng and the cortex rotundae officinalis are used as guiding drugs, wherein the radix notoginseng and the cortex rotundae officinalis have the effects of clearing heat, promoting diuresis, relieving swelling and pain, and the cortex rotundae officinalis can dispel wind-damp, tonify qi and blood and strengthen waist and knee; the medicines are combined to promote menstruation and blood circulation, so that the medicinal components in the medicinal materials pass through twelve channels and walk throughout the whole body, and the medicinal liquor has super-strong permeability, can quickly permeate into the affected parts of patients and directly reach the focus. The medicated wine is prepared by sealing and soaking selected Chinese herbal medicines with the effects of promoting blood circulation to remove meridian obstruction, dispelling wind and eliminating dampness, and relieving swelling and pain, has strong medicinal efficacy, can quickly permeate into affected parts of patients, has the functions of removing toxic substances and removing stasis, diminishing inflammation and sterilizing, dispelling wind and eliminating dampness, strengthening tendons and bones, relieving swelling and pain, and repairing damaged tissues and cells, and achieves the real rehabilitation. The Chinese medicinal composition has reasonable compatibility, and can be used for treating various arthralgia, soreness of waist and knee, tendons and bones weakness, rheumarthritis, lumbago and skelalgia, lumbar muscle strain, etc.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.
It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The present application will be described in detail with reference to specific examples.
A traditional Chinese medicine wine for treating arthralgia comprises white wine and the following raw materials in parts by weight: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of lycopodium clavatum, 120-300 parts of fructus liquidambaris, 120-300 parts of mistletoe, 120-300 parts of nux vomica, 120-300 parts of radix aconiti, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of radix philippine fleeceflower root and 80-250 parts of holly bark.
Ai Cao is bitter and pungent in flavor and warm in nature, entering spleen, liver and kidney. Has effects in warming channel, removing dampness, dispelling cold, stopping bleeding, relieving inflammation and asthma, relieving cough, preventing miscarriage, and resisting allergy. Menoxenia, dysmenorrhea, abdominal pain, abortion, metrorrhagia, and rheumarthritis, head wind, and intra-month wind. The pure yang nature can restore the drastic yang, unblock the twelve channels, pass three yin, regulate qi and blood, dispel cold-dampness, warm uterus, and can dispel various diseases through the channels by moxibustion fire.
Jie mu enters liver meridian. Sweet and bitter in flavor and neutral in nature. Has effects of promoting reunion of bone, promoting blood circulation, relieving pain, dispelling pathogenic wind, and promoting diuresis. Can be used for treating fracture, traumatic injury, rheumatic arthritis, gout, and bone joint diseases, acute and chronic nephritis; it is used for treating traumatic hemorrhage.
Gao Ling enters liver and kidney meridians. Pungent and bitter in flavor and warm in nature. It is slightly toxic. Has effects in dispelling pathogenic wind, removing dampness, removing toxic substances, and relieving pain. Can be used for treating rheumatic arthralgia; it is indicated for sores and ulcers and other sores with toxic swelling.
Spatholobus stem enters liver and kidney meridians. Bitter and sweet in flavor and warm in nature. Has effects of replenishing blood, promoting blood circulation, and dredging collaterals. It can be used for treating menoxenia, blood deficiency, sallow complexion, numbness, paralysis, and rheumatalgia.
The herb of common clubmoss enters liver, spleen and kidney meridians. Slightly bitter and pungent in flavor and warm in nature. Has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, and activating collaterals. Can be used for treating joint pain and difficulty in flexing and extending.
Lipuidambaris enters liver and kidney meridians. Bitter taste and neutral nature. Has effects of dispelling pathogenic wind, activating collaterals, promoting diuresis and dredging channels. Can be used for treating arthralgia, numbness, contracture, edema, fullness, and amenorrhea due to hypogalactia.
Loranthus mulberry mistletoe enters liver and kidney meridians. Bitter and sweet in flavor and neutral in nature. Has effects in nourishing liver and kidney, strengthening tendons and bones, dispelling pathogenic wind and dampness, and relieving fetal irritability. Can be used for treating rheumatalgia, soreness of waist and knees, weakness of tendons and bones, metrorrhagia, menorrhagia, blood leakage during pregnancy, and fetal irritability; hypertension.
Nux vomica enters liver and spleen meridians. Bitter taste and warm nature; it is toxic. Has effects of dredging collaterals, relieving pain, resolving hard mass and detumescence. Can be used for treating rheumatism, numbness, paralysis, traumatic injury, carbuncle, and swelling and pain; infantile paralysis sequelae, rheumatoid arthralgia.
Chuan Wu enters heart, liver, kidney and spleen meridians. Pungent and bitter in taste and warm in nature; it is toxic. Has effects in dispelling pathogenic wind, removing dampness, warming channel, and relieving pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia pain, and anesthesia and pain.
Brother Wang Guixin; a lung; the small intestine channel. Bitter and pungent taste; cold property; is toxic. Has effects in clearing away heat and toxic materials; resolving phlegm and resolving masses; swelling and pain relieving effects. Carbuncle swelling and sore; scrofula; rheumatalgia; traumatic injury; snake and insect bite
Notoginseng radix enters liver and stomach meridians. Sweet and slightly bitter in taste and warm in nature. Has effects of removing blood stasis, stopping bleeding, relieving swelling and relieving pain. Can be used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracocentesis pain, and traumatic injury.
The flemingia is entered into the lung, kidney and bladder meridians. Sweet in flavor, slightly warm in nature and flat. Has effects in dispelling pathogenic wind and dampness, and strengthening waist and knee. Can be used for treating rheumatic arthritis, lumbago, skelalgia, lumbar muscle strain, leucorrhea, and traumatic injury.
Jiujiujiujiujiujiujiu enters lung, liver and large intestine meridians. Bitter taste; it is cold in nature. Has effects in clearing away heat and toxic materials; diuresis; analgesic effect. The main common cold is febrile; sore throat; stomach ache; diarrhea due to damp invasion; jaundice; dysentery; traumatic injury; rheumatalgia; eczema; sore and furuncle.
In some embodiments of the application, the traditional Chinese medicine wine for treating arthralgia further comprises 300-600 parts of pepper and 300-600 parts of pricklyash peel. The pricklyash peel and the pricklyash peel are matched with each other, so that the pricklyash peel and the pricklyash peel have the effects of strengthening and stimulating the superficial skin, expanding pores and promoting the rapid absorption of liquid medicine.
In some embodiments of the application, the traditional Chinese medicine wine for treating arthralgia comprises white wine and the following raw materials in parts by weight: 480-520 parts of wormwood, 250-300 parts of elderberry, 250-300 parts of garden balsam stem, 250-300 parts of suberect spatholobus stem, 250-300 parts of lycopodium clavatum, 180-250 parts of fructus liquidambaris, 180-250 parts of mistletoe, 180-250 parts of nux vomica, 180-250 parts of radix aconiti, 180-250 parts of Indian stringbush root, 140-250 parts of pseudo-ginseng, 140-250 parts of radix philippine fleeceflower, 140-250 parts of holly bark, 350-550 parts of pricklyash peel and 350-550 parts of finger-day pepper.
In some embodiments of the application, the traditional Chinese medicine wine for treating arthralgia comprises white wine and the following raw materials in parts by weight: 500 parts of wormwood, 250 parts of sambucus chinensis, 250 parts of garden balsam stem, 250 parts of suberect spatholobus stem, 250 parts of lycopodium clavatum, 250 parts of fructus liquidambaris, 250 parts of mistletoe, 250 parts of nux vomica, 250 parts of radix aconiti, 250 parts of Indian stringbush root, 250 parts of pseudo-ginseng, 250 parts of radix philippine flemingiae, 250 parts of cortex rotundae, 500 parts of pepper and 500 parts of finger-like pricklyash peel.
In some embodiments of the present application, the mass ratio of the white spirit to the raw materials is 1:6-8. Under the proportion, the active ingredients in the medicinal materials can be better and faster dissolved, the white wine is large enough, and the sterilizing effect is achieved, so that the medicinal materials are in a sterile environment, and the medicinal wine can be better preserved.
In some embodiments of the present application, the degree of the white spirit is 45 to 60 degrees. The white spirit is a good solvent, is easy to enter into tissue cells of medicinal materials, can dissolve out most water-soluble substances and organic substances which are insoluble in water and are dissolved by nonpolar solvents in the medicinal materials, and the white spirit with high alcohol content can enable active ingredients in the medicinal materials to be dissolved out rapidly, but the white spirit with high alcohol content is not higher, better, and is suitable for 45-60 degrees.
A preparation method of traditional Chinese medicine wine for treating arthralgia comprises the following steps:
parching semen Strychni with sand; soaking radix Aconiti in water, taking out when the taste has spicy taste, mixing sand-parched semen Strychni and soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, semen Strychni, radix Wikstroemia indica, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
mixing and soaking the dried raw materials with the distilled spirit, filtering to remove impurities, distilling the filtered medicinal liquid to obtain an extracting solution, extracting the extracting solution, and sealing and storing to obtain the medicinal liquor.
In some embodiments of the application, the soaking time is 10-15 days. The soaking is to dissolve the effective substances in the medicinal materials into the white spirit for too short time, and the effective substances in the medicinal materials are completely dissolved into the white spirit; the soaking time is too long, and the drug effect is affected, so that soaking for 10-15 days is suitable.
In some embodiments of the application, the storage temperature is 25-30 ℃. Under the condition, the medicated wine is stored for a longer time, and is not easy to deteriorate.
In some embodiments of the present application, the above-mentioned sand-frying temperature is 160-250 ℃ and the sand-frying time is 4-15 min. The content of toxic substances in the processed semen Strychni can be well controlled by controlling the sand frying temperature and the sand frying time. Under the condition, the strychnos are stir-fried with sand, the strychnos main toxic substances strychnine and strychnine are converted into strychnos and strychnine nitrogen oxides with low toxicity, similar curative effect and better pharmacological action through thermalization, or ether bond ring opening is converted into a special structure, so that the strychnos main toxic substances strychnos and strychnos main toxic substances strychnos are converted into strychnos nitrogen oxides with low alkaloid reduction rate but high toxicity reduction rate, and the effective components of the strychnos are reserved.
The features and capabilities of the present application are described in further detail below in connection with the examples.
Example 1
A traditional Chinese medicine wine for treating arthralgia can comprise white wine and the following raw materials in parts by weight: 500g of wormwood, 250g of sambucus chinensis, 250g of garden balsam stem, 250g of suberect spatholobus stem, 250g of lycopodium clavatum, 250g of fructus liquidambaris, 250g of Chinese taxillus herb, 250g of nux vomica, 250g of common monkshood mother root, 250g of Indian stringbush root, 250g of sanchi, 250g of flemingia root, 250g of holly bark, 500g of Chinese prickly ash and 500g of finger-like prickly ash.
The preparation method comprises the following steps: parching semen Strychni with sand at 200deg.C for 12min; soaking radix Aconiti in water, changing water 2 times daily, rinsing until the taste is slightly spicy; mixing the sand-fried semen Strychni and the soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, indian Stringbush, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1:7, soaking for 12 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain extractive solution, extracting at-25deg.C to obtain medicated liquor, sealing, and storing in shade.
Example 2
A traditional Chinese medicine wine for treating arthralgia can comprise white wine and the following raw materials in parts by weight: 480g of wormwood, 280g of sambucus chinensis, 280g of garden balsam stem, 280g of suberect spatholobus stem, 280g of lycopodium clavatum, 280g of fructus liquidambaris, 280g of Chinese taxillus herb, 280g of nux vomica, 280g of common monkshood mother root, 280g of Indian stringbush root, 280g of pseudo-ginseng, 280g of philippine flemingia root, 280g of holly bark, 350g of Chinese prickly ash and 350g of pricklyash peel.
The preparation method comprises the following steps: parching semen Strychni with sand at 160deg.C for 8min; soaking radix Aconiti in water, changing water 2 times daily, rinsing until the taste is slightly spicy; mixing the sand-fried semen Strychni and the soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, indian Stringbush, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1:6, soaking for 10 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at a low temperature of minus 30 ℃ to obtain medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 3
A traditional Chinese medicine wine for treating arthralgia can comprise white wine and the following raw materials in parts by weight: 520g of wormwood, 300g of sambucus chinensis, 300g of garden balsam stem, 260g of suberect spatholobus stem, 250g of lycopodium clavatum, 250g of fructus liquidambaris, 250g of Chinese taxillus herb, 250g of nux vomica, 280g of common monkshood mother root, 280g of Indian stringbush root, 280g of sanchi, 250g of flemingia root, 250g of holly bark, 400g of Chinese prickly ash and 400g of finger-like prickly ash.
The preparation method comprises the following steps: parching semen Strychni with sand at 250deg.C for 4min; soaking radix Aconiti in water, changing water 2 times daily, rinsing until the taste is slightly spicy; mixing the sand-fried semen Strychni and the soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, indian Stringbush, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1:6.5, soaking for 15 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extract, extracting the extract at a low temperature of-20 ℃ to obtain medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 4
A traditional Chinese medicine wine for treating arthralgia can comprise white wine and the following raw materials in parts by weight: 500g of wormwood, 260g of sambucus chinensis, 260g of garden balsam stem, 280g of suberect spatholobus stem, 280g of lycopodium clavatum, 290g of fructus liquidambaris, 180g of Chinese taxillus herb, 180g of nux vomica, 180g of common monkshood mother root, 180g of Indian stringbush root, 140g of sanchi, 140g of flemingia root, 140g of holly bark, 350g of Chinese prickly ash and 350g of finger-like pricklyash.
The preparation method comprises the following steps: parching semen Strychni with sand at 190 deg.C for 10min; soaking radix Aconiti in water, changing water 2 times daily, rinsing until the taste is slightly spicy; mixing the sand-fried semen Strychni and the soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, indian Stringbush, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
and mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1:7.5, mixing and soaking for 13 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at a low temperature of-23 ℃ to obtain medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 5
A traditional Chinese medicine wine for treating arthralgia can comprise white wine and the following raw materials in parts by weight: 520g of wormwood, 300g of sambucus chinensis, 300g of garden balsam stem, 300g of suberect spatholobus stem, 300g of lycopodium clavatum, 250g of fructus liquidambaris, 250g of Chinese taxillus herb, 250g of nux vomica, 250g of common monkshood mother root, 250g of Indian stringbush root, 250g of sanchi, 250g of flemingia root, 250g of holly bark, 450g of Chinese prickly ash and 450g of finger-like prickly ash.
The preparation method comprises the following steps: parching semen Strychni with sand at 160deg.C for 12min; soaking radix Aconiti in water, changing water 2 times daily, rinsing until the taste is slightly spicy; mixing the sand-fried semen Strychni and the soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, indian Stringbush, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1:8, soaking for 15 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extract, extracting the extract at a low temperature of-26 ℃ to obtain medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 6
A traditional Chinese medicine wine for treating arthralgia can comprise white wine and the following raw materials in parts by weight: 500g of wormwood, 260g of sambucus chinensis, 260g of garden balsam stem, 250g of suberect spatholobus stem, 250g of lycopodium clavatum, 200g of fructus liquidambaris, 200g of mistletoe, 200g of nux vomica, 200g of radix aconiti, 200g of radix notoginseng, 200g of radix philippici, 200g of cortex pseudostellariae and 200g of cortex rotundae.
The preparation method comprises the following steps: parching semen Strychni with sand at 170deg.C for 6min; soaking radix Aconiti in water, changing water 2 times daily, rinsing until the taste is slightly spicy; mixing the sand-fried semen Strychni and the soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, indian Stringbush, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1:7, soaking for 10 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extract, extracting the extract at low temperature of-24 ℃ to obtain medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Comparative example
This comparative example is substantially the same as example 1 except that no mugwort is added.
Effect example
22 cases of patients suffering from hyperosteogeny, 24 cases of patients suffering from lumbar disc herniation (bulge and slippage), 20 cases of patients suffering from lumbar spinal stenosis, 19 cases of patients suffering from ankylosing spondylitis, 27 cases of patients suffering from cervical spondylosis (hyperplasia, herniation, bulge and stenosis), 21 cases of patients suffering from rheumatic arthritis gall, 18 cases of patients suffering from rheumatoid arthritis pain, 15 cases of patients suffering from sciatica and 15 cases of patients suffering from lumbar muscle strain are selected.
The patients were randomized into 7 groups, each without significant differences.
The using method comprises the following steps:
the medicinal liquor is taken to be smeared on a diseased part or a body pain uncomfortable part, and can be smeared once in the morning, in the middle and in the evening, the patient with serious symptoms can be smeared for 5 to 6 times in one day, the smeared part is cleaned or disinfected by iodine solution before being smeared, 7 days is a treatment course, three continuous treatment courses are optimal, and the medicinal effect is counted after one treatment course.
Notice that: a. disabled for alcohol allergy sufferers; b. the pregnant woman is forbidden; c. avoid menstrual period; d. the traumatic injury is forbidden for no more than 24 hours; e. if precipitation exists, the use effect is not affected.
Efficacy assessment criteria:
and (3) curing: the pain symptoms disappear, the shoulder and neck ache signs disappear, the detection indexes meet the regulations, and the functions are recovered to be normal;
the effect is shown: the pain symptoms disappear, the shoulder and neck ache signs are obviously relieved, the detection indexes are qualified, and the normal life is not influenced;
the method is effective: symptom relief, which has an influence on life;
invalidation: the symptoms are not improved, and the symptoms have a tendency of aggravating, and other medicaments are needed to be selected for treatment.
The specific statistics are shown in table 1.
TABLE 1
Effective rate= (effective number + healed number)/total number;
cure rate = number of cured people/total number of people;
as can be seen from Table 1, the effective rates of examples 1 to 6 and comparative example are 100%, the cure rate of example 1 is 93%, and it is seen that the medicated wine prepared in example 1 has the best effect; in the comparative example, the cure rate of the Chinese mugwort is 81% without adding the Chinese mugwort, and the Chinese mugwort is the main medicine in the Chinese medicinal composition of the application, thus playing an important role in the Chinese medicinal composition; in the example 6, no pricklyash peel and pricklyash peel are added, the cure rate is 88%, and the pricklyash peel and pricklyash peel are matched with each other, so that the skin on the surface layer is stimulated, pores are expanded, and the quick absorption of the liquid medicine is promoted.
Typical case 1: zhou Mou when a man, 51 years old, suffers from lumbar disc herniation for 5 years, frequently suffers from lumbar vertebra pain, and can only take analgesic to force pain when the man cannot sit for a long time and stand for a long time; the effect is poor after the treatment in the hospital, pain frequently and repeatedly attacks, and the effect of obvious relief is not achieved after the physiotherapy is carried out. After the medicinal liquor is externally applied for 2 days, the lumbar pain is obviously improved, and after the medicinal liquor is continuously used for 1 treatment course, the pain symptoms completely disappear, and the medicinal liquor is used intermittently and does not relapse.
Typical case 2: when a woman is in a certain state, 32 years old, a person can work by sitting on the table for a long time, lumbar vertebra strain is serious and is accompanied by scapulohumeral periarthritis and cervical vertebra hyperplasia, various methods are tried to treat, for example, effects of anti-inflammatory analgesic drugs, massage, acupuncture and the like are poor, waist is inflated when the person cannot bend down and sleep at ordinary times, the person cannot fall asleep, normal life work is influenced, after the person is applied to the person for 3 days by using the medicated wine, lumbar vertebra pain is obviously improved, pain symptoms thoroughly disappear after the person continues to use for 1 treatment course, and normal work and life can be realized.
In summary, according to the traditional Chinese medicine wine for treating arthralgia and the preparation method thereof, in the traditional Chinese medicine composition, the mugwort leaves through twelve channels and three yin, has the effects of dispelling wind and removing dampness, clearing and activating the channels and collaterals, and reducing swelling and resolving masses, is pure yang, can be used for moxibustion fire, can penetrate all channels and remove hundred diseases, and is a monarch drug; the elder, the garden balsam stem, the suberect spatholobus stem and the common clubmoss herb are matched with each other, can dispel wind and remove dampness, relax tendons and activate blood, reduce swelling and relieve pain, are ministerial drugs, can be used for treating joint ache by matching with monarch drugs, and are disadvantageous in flexion and extension; fructus Lipuidambaris, herba Taxilli, semen Strychni, radix Aconiti and Indian Stringbush are used as adjuvant drugs, wherein the fructus Lipuidambaris and the Indian Stringbush are matched with each other, and can clear away heat and toxic materials, promote diuresis and promote menstruation; the nux vomica and the common monkshood mother root are matched with each other, so that the Chinese medicinal composition can remove meridian obstruction, relieve pain, dissipate stagnation and reduce swelling; loranthus mulberry mistletoe can tonify liver and kidney and strengthen tendons and bones; can be used in combination with monarch drug for treating rheumatalgia, soreness of waist and knees, weakness of tendons and bones, etc.; 37. the radix notoginseng and the cortex rotundae officinalis are used as guiding drugs, wherein the radix notoginseng and the cortex rotundae officinalis have the effects of clearing heat, promoting diuresis, relieving swelling and pain, and the cortex rotundae officinalis can dispel wind-damp, tonify qi and blood and strengthen waist and knee; the medicines are combined to promote menstruation and blood circulation, so that the medicinal components in the medicinal materials pass through twelve channels and walk throughout the whole body, and the medicinal liquor has super-strong permeability, can quickly permeate into the affected parts of patients and directly reach the focus. The medicated wine is prepared by sealing and soaking selected Chinese herbal medicines with the effects of promoting blood circulation to remove meridian obstruction, dispelling wind and eliminating dampness, and relieving swelling and pain, has strong medicinal efficacy, can quickly permeate into affected parts of patients, has the functions of removing toxic substances and removing stasis, diminishing inflammation and sterilizing, dispelling wind and eliminating dampness, strengthening tendons and bones, relieving swelling and pain, and repairing damaged tissues and cells, and achieves the real rehabilitation. The Chinese medicinal composition has reasonable compatibility, and can be used for treating various arthralgia, soreness of waist and knee, tendons and bones weakness, rheumarthritis, lumbago and skelalgia, lumbar muscle strain, etc.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
Claims (9)
1. The traditional Chinese medicine wine for treating arthralgia is characterized by comprising white wine and the following raw materials in parts by weight: 450-550 parts of wormwood, 230-400 parts of sambucus chinensis, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of common clubmoss herb, 120-300 parts of fructus liquidambaris, 120-300 parts of mistletoe, 120-300 parts of nux vomica, 120-300 parts of radix aconiti, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of radix philippine fleeceflower, 80-250 parts of holly bark, 300-600 parts of pricklyash peel and 300-600 parts of pricklyash peel.
2. The traditional Chinese medicine wine for treating arthralgia according to claim 1, which is characterized by comprising white wine and the following raw materials in parts by weight: 480-520 parts of wormwood, 250-300 parts of elderberry, 250-300 parts of garden balsam stem, 250-300 parts of suberect spatholobus stem, 250-300 parts of lycopodium clavatum, 180-250 parts of fructus liquidambaris, 180-250 parts of mistletoe, 180-250 parts of nux vomica, 180-250 parts of radix aconiti, 180-250 parts of Indian stringbush root, 140-250 parts of pseudo-ginseng, 140-250 parts of radix philippine fleeceflower, 140-250 parts of holly bark, 350-550 parts of pricklyash peel and 350-550 parts of finger-day pepper.
3. The traditional Chinese medicine wine for treating arthralgia according to claim 2, which is characterized by comprising white wine and the following raw materials in parts by weight: 500 parts of wormwood, 250 parts of sambucus chinensis, 250 parts of garden balsam stem, 250 parts of suberect spatholobus stem, 250 parts of lycopodium clavatum, 250 parts of fructus liquidambaris, 250 parts of mistletoe, 250 parts of nux vomica, 250 parts of radix aconiti, 250 parts of Indian stringbush root, 250 parts of pseudo-ginseng, 250 parts of radix philippine flemingiae, 250 parts of cortex rotundae, 500 parts of pepper and 500 parts of finger-like pricklyash peel.
4. The traditional Chinese medicine wine for treating arthralgia according to claim 3, wherein the mass ratio of the white wine to the raw materials is 1:6-8.
5. The traditional Chinese medicinal liquor for treating arthralgia according to any one of claims 1-4, wherein the degree of white spirit is 45-60 degrees.
6. A method for preparing a medicated liquor according to any one of claims 1 to 5 for the treatment of joint pain, comprising the steps of:
parching semen Strychni with sand; soaking radix Aconiti in water, taking out when the taste has spicy taste, mixing semen Strychni and soaked and bleached radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba Speranskiae Tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, radix Wikstroemia indica, notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
and mixing and soaking the dried raw medicinal materials with the white spirit, filtering to remove impurities, distilling the filtered medicinal liquid to obtain an extracting solution, extracting the extracting solution, and sealing and storing to obtain the medicinal liquor.
7. The method for preparing the traditional Chinese medicine wine for treating arthralgia according to claim 6, wherein the soaking time is 10-15 days.
8. The method for preparing the traditional Chinese medicine wine for treating arthralgia according to claim 6, wherein the extraction temperature is-30 to-20 ℃.
9. The method for preparing the traditional Chinese medicine wine for treating arthralgia according to claim 6, wherein the sand-frying temperature is 160-250 ℃ and the sand-frying time is 4-15 min.
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| CN104258209A (en) * | 2014-09-25 | 2015-01-07 | 苏州市天灵中药饮片有限公司 | External medicinal liquor for treating gout and preparation method thereof |
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