CN103393916B - External use ointment used for treating dermatitis and preparation method thereof - Google Patents

External use ointment used for treating dermatitis and preparation method thereof Download PDF

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CN103393916B
CN103393916B CN201310334404.XA CN201310334404A CN103393916B CN 103393916 B CN103393916 B CN 103393916B CN 201310334404 A CN201310334404 A CN 201310334404A CN 103393916 B CN103393916 B CN 103393916B
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herba
folium
dermatitis
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CN103393916A (en
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赵洪乾
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Abstract

The invention relates to an external use ointment used for treating dermatitis and a preparation method thereof. An effective compound of the external use ointment comprises following raw materials: caragana microphylla, sundew, alternanthera sessilis, convolvulus arvensis, excoecaria sebifera, acronychia leaf, wing nut leaf, kazinoki broussonetia, calamint, gingium verum, vitex trifolia, ferb of desertliving asparagus, chenopodium album seed, mosla scabra, fruit of siberian nitraria and lantana camara. The external use ointment has efficacies of clearing heat and removing toxicity, eliminating dampness and relieving itching, and coursing wind and nourishing blood; and has significant effects on treatment of allergic dermatitis, atopic dermatitis, neurodermatitis, seborrheic dermatitis and dermatitis medicamentosa; possesses excellent curative effects on common dermatitis diseases such as erythema, papule, rahagades, desquamation, small abscess, pruritus, tenderness and burning heat sensation; and is capable of killing bacteria on human skin surface rapidly and efficiently, removing corrupted materials, promoting optimization and growth of epidermis cells effectively, enhancing plastid of epidermis cells, and helping damaged human body to recover rapidly.

Description

A kind of external-applied ointment and preparation method for the treatment of dermatitis
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of external-applied ointment and preparation method for the treatment of dermatitis.
Background technology
Dermatitis refers to a kind of scytitis, and common dermatitis kind has allergic dermatitis, abnormal flavour dermatitis, neurodermatitis, seborrheic dermatitis, drug eruption etc.; Common dermatitis symptom has erythema, pimple, chaps, desquamation, little abscess, pruritus, tenderness and burning sensation etc.
The cause of disease of dermatitis is varied, is broadly divided into the factors such as mechanicalness, chemical, fungoid, parasitic, anaphylaxis; In addition, bad living habit, as conventional overheated water face-washing; or overfrequency ground uses the skin cleaners such as fancy soap, cleansing milk; do not note at ordinary times ultraviolet protection etc., these physicochemical irritations all can change or protective barrier and the regulation of blood vessels function of injured skin, cause the generation of dermatitis.
Dermatitis is a kind of disease occurred frequently, and the symptom main manifestations showing due to dermatitis, in skin surface, has brought inconvenience to patient's daily life and human communication, thereby, cause very large injury to patient's health and soul.For dermatitis patients, accomplish early to find if can not treat in time, to miss golden hour by early treatment, may cause otherwise disease, even cause skin carcinoma.
The medicine of existing treatment dermatitis is mostly Western medicine, western medicine dermatitis has instant effect, the fast feature of curative effect, but, most Western medicine medicine contains hormone and chemical composition, large to human body side effect, and easily recurrence, can not effect a radical cure dermatitis after treating, make dermatitis patients tired in the rear relapse of reply.
Because Chinese Traditional Chinese Medicine medical material lasting medicine, toxic and side effects are little, for this reason, we transfer to Chinese medicine research in theory by research emphasis, wish the Chinese medicine preparation that a kind of applicable dermatitis patients of development uses, and provide convenience to dermatitis patients.
Summary of the invention
The invention provides a kind of external-applied ointment and preparation method for the treatment of dermatitis, external-applied ointment of the present invention has heat-clearing and toxic substances removing, removing damp to relieve itching, effect that dispelling wind nourishes blood, for treatment allergic dermatitis, abnormal flavour dermatitis, neurodermatitis, seborrheic dermatitis, drug eruption texts is obvious, for erythema, pimple, chap, desquamation, little abscess, pruritus, the common dermatitis diseases such as tenderness and burning sensation have significant curative effect, can kill quickly and efficiently the various antibacterials in human body skin surface, the material of eliminating corruption, effectively promote optimization and the growth of epidermis cell, strengthen the plastid of epidermis cell, diminish inflammation, make the rapid rehabilitation of injured human body.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat an external-applied ointment for dermatitis, raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
41~70 parts of 45~75 parts of Herba seu Flos Convolvuli arvensves of 48~78 parts of Alternanthera sessilis (L.) DC.s of 50~80 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
30~60 parts of 35~62 parts of Folium et Cacumen Broussonetiae Kazinoki of 38~65 parts of Folium pterocaryae stenopteraes of 40~69 parts of Folium Phyllanthi of Cortex Sapii Radicis
20~45 parts of 22~50 parts of Herba asparagi gobicis of 25~55 portions of five-leaved chaste trees of 28~57 parts of Herba galii veris of Herba Clinopodii Polycephali
10~30 parts of 13~35 parts of Folium Lantanae Camaraes of real 17~42 parts of peaceful 15~40 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
Raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
46~65 parts of 50~70 parts of Herba seu Flos Convolvuli arvensves of 53~73 parts of Alternanthera sessilis (L.) DC.s of 55~75 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
35~55 parts of 40~57 parts of Folium et Cacumen Broussonetiae Kazinoki of 41~62 parts of Folium pterocaryae stenopteraes of 45~64 parts of Folium Phyllanthi of Cortex Sapii Radicis
25~40 parts of 27~45 parts of Herba asparagi gobicis of 30~50 portions of five-leaved chaste trees of 33~52 parts of Herba galii veris of Herba Clinopodii Polycephali
13~28 parts of 17~31 parts of Folium Lantanae Camaraes of real 22~38 parts of peaceful 18~37 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
Raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
51~60 parts of 55~65 parts of Herba seu Flos Convolvuli arvensves of 58~68 parts of Alternanthera sessilis (L.) DC.s of 60~70 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
40~50 parts of 45~52 parts of Folium et Cacumen Broussonetiae Kazinoki of 46~57 parts of Folium pterocaryae stenopteraes of 50~60 parts of Folium Phyllanthi of Cortex Sapii Radicis
28~37 parts of 32~40 parts of Herba asparagi gobicis of 35~45 portions of five-leaved chaste trees of 38~47 parts of Herba galii veris of Herba Clinopodii Polycephali
16~22 parts of 22~27 parts of Folium Lantanae Camaraes of real 27~34 parts of peaceful 23~32 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
Raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
56 parts of 60 parts of Herba seu Flos Convolvuli arvensves of 63 parts of Alternanthera sessilis (L.) DC.s of 65 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
45 parts of 48 parts of Folium et Cacumen Broussonetiae Kazinoki of 51 parts of Folium pterocaryae stenopteraes of 55 parts of Folium Phyllanthi of Cortex Sapii Radicis
33 parts of 37 parts of Herba asparagi gobicis of 40 portions of five-leaved chaste trees of 42 parts of Herba galii veris of Herba Clinopodii Polycephali
19 parts of 24 parts of Folium Lantanae Camaraes of the real 31 parts of peaceful 27 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
Treat a preparation method for the external-applied ointment of dermatitis, comprise following processing step:
(1) Herba Droserae Lunatae, Herba seu Flos Convolvuli arvensis, Folium pterocaryae stenopterae and Herba Ainsliaea Albotomentosae are put into container, add the ethanol of 4 times of amounts, soak after 2~3 hours and filter, get filtrate, be condensed into the thick paste of relative density 1.20~1.22 at 60 DEG C, for subsequent use;
(2) Alternanthera sessilis (L.) DC., Herba Clinopodii Polycephali, stone shepherd's purse peace Folium Lantanae Camarae are cleaned up, mash, strand juice, with filtered through gauze twice, taking juice, for subsequent use;
(3) by real to Herba Caraganae intermediae, Cortex Sapii Radicis, Folium Phyllanthi, Folium et Cacumen Broussonetiae Kazinoki, Herba galii veri, five-leaved chaste tree, Herba asparagi gobici and the Herba chenopodii container of putting into, adding distil water boils and extracts 3 times, adds first 10-15 and doubly measures distilled water immersion 4-5 hour, and heated and boiled 3-4 hour, extracts; Add for the second time 8-10 and doubly measure distilled water heated and boiled 2-3 hour, extract; Add for the third time 6-8 and doubly measure distilled water heated and boiled 1~2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, concentrate and to be dried to dry extract for subsequent use;
(4) thick paste made above-mentioned steps (1)-(3), juice and dry extract are mixed, utilize modern advanced pharmacy science and technology, make ointment, obtain the external-applied ointment for the treatment of dermatitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Caraganae intermediae: sweet in the mouth, warm in nature.Return liver, kidney channel.Nourishing YIN and supplementing blood, invigorates blood circulation, antipruritic, parasite killing.Cure mainly hypertension, dizziness, nervous, breathe hard, myasthenia of limbs, tired, menoxenia, neurodermatitis, psoriasis, impetigo.
Herba Droserae Lunatae: sweet in the mouth, pungent, property is flat, nontoxic.Return spleen, stomach, lung meridian.Wind-expelling pain-stopping, promoting blood circulation and stopping pain, removing toxic substances.Main traumatic injury, lumbar muscle strain, rheumatic arthritis, malaria (subsides DAZHUI acupoint), corneal nebula (subsides temple), tuberculous lymphadenitis, neurodermatitis, stomachache, flu, laryngopharynx swelling and pain, dysentery, malaria, infantile malnutrition, corneal nebula, scrofula, eczema, scabies.Clinical research confirmation, Herba Droserae Lunatae has treatment rheumatism, rheumatoid arthritis, treatment neurodermatitis, the part effect only of itching.
Alternanthera sessilis (L.) DC.: micro-sweet, light, cool in nature.Clearing away heat and cooling blood, inducing diuresis and reducing edema, draw out pus by applying a plaster to the affected part antipruritic.For dysentery, epistaxis, spitting of blood, has blood in stool, urethritis, and pharyngitis, mastitis, dysuria, furuncle toxic swelling, eczema, dermatitis, tinea corporis, venom are controlled in external.
Herba seu Flos Convolvuli arvensis: acrid in the mouth, warm in nature, poisonous.Return kidney channel.Dispelling wind for relieving itching, pain relieving.Main air pain of dampness syndrome, toothache, neurodermatitis.
Cortex Sapii Radicis: bitter in the mouth, slightly warm in nature.Slightly poisonous.Enter lung, spleen, kidney, large intestine channel.Parasite killing, removing toxic substances, diuresis, relieving constipation.For schistosomicide, cirrhotic ascites, defecation is unfavorable, venom, and furuncle is controlled in external, clavus, mastitis, traumatic injury, eczema, dermatitis.
Folium Phyllanthi: sweet in the mouth, micro-hardship, cool in nature.GUIXIN, liver, large intestine channel.Heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Main aphtha, furuncle, eczema, dermatitis, edema, hypertension.Venom, traumatic injury." Luchuan book on Chinese herbal medicine " carries: " sterilization removing the necrotic tissue.Control erosion of mucous membrane of the oral cavity, eczema of scrotum and infantile malnutrition, furuncle, leakage, hemorrhoid.”
Folium pterocaryae stenopterae: acrid in the mouth, hardship, warm in nature, poisonous.Return lung, Liver Channel.Wind-expelling pain-stopping, killing parasites for relieving itching, removing toxic substances sore.Main air pain of dampness syndrome, toothache, knee-joint pain, scabies, eczema, trichomonas vaginitis, scalds wound, ulcer being unable to heal, schistosomicide, cough and asthma." classification medical herbs " carries: " wash scabies, tinea skin ulcer.”
Folium et Cacumen Broussonetiae Kazinoki: sweet in the mouth, light, property is flat.Return liver, kidney, urinary bladder channel.Expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling.Main air pain of dampness syndrome, has loose bowels, dysentery, jaundice, edema, carbuncle furuncle, traumatic injury.Dispel the wind, invigorate blood circulation, diuresis, dermatitis.Carry Jinhua " conventional Chinese herbal folk proved recipe a collection of selected materials ": " expelling wind and activating blood circulation, removing toxic substances diuresis.Dispelling the wind and dampness pathogens arthralgia pain, bubon.”
Herba Clinopodii Polycephali: acrid in the mouth, hardship, cool in nature.Wind and heat dispersing, removing toxic substances and promoting subsidence of swelling, hemostasis.Main cold, fever, heatstroke, laryngopharynx swelling and pain, diphtheria, acute cholecystitis, hepatitis, enteritis, dysentery inflammation, dysentery, rib adenitis, mastitis, furuncle swelling toxin, allergic dermatitis, acute conjunctivitis, hematuria, metrorrhagia, gingival hemorrhage, traumatic hemorrhage." Zhejiang conventional medical herbs among the people " carries: " dispelling wind feelings heat, removing toxic substances dysentery relieving.Cure cold, heatstroke, allergic dermatitis, dactylitis, dysentery.”
Herba galii veri: taste is micro-pungent, bitter, cold nature.Heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow, dispelling wind for relieving itching.Main hepatitis, ascites, laryngopharynx swelling and pain, furuncle toxic swelling, traumatic injury, women's amenorrhea, leukorrhagia, venom, honor measles, paddy field dermatitis." Chinese herbal medicine handbook is commonly used in northeast " carries: " detumescence blood stasis dispelling, detoxifying and relieving itching.Control acute urticaria, furuncle furunculosis.”
Five-leaved chaste tree: bitter in the mouth, micro-pungent, property is flat, clearing and antitussive, the preventing the attack (or recurrence) of malaria that reduces phlegm, regulating QI to relieve pain.For bronchitis, malaria, hepatitis, for flu, enteritis, dysentery, malaria, urinary system infection, cough, asthma, stomachache, dyspepsia, enteritis, dysentery.Eczema is controlled in external, dermatitis, and tinea pedis, decocts soup washout.
Herba asparagi gobici: acrid in the mouth, micro-hardship, property is flat.Return Liver Channel.Dispel the wind, parasite killing, antipruritic, eliminating carbuncle eliminating stagnation.Main neurodermatitis, psoriasis, tinea corporis, furuncle carbuncle." Ningxia Chinese herbal medicine handbook " carries: " dispel the wind, parasite killing, antipruritic.”
Herba chenopodii is real: bitter in the mouth, micro-sweet, cold in nature, mild toxicity; Clearing heat and expelling damp, killing parasites for relieving itching.Cure mainly dysuria, edema, skin eczema, head sore, deafness.
Stone shepherd's purse is peaceful: acrid in the mouth, slightly warm in nature.Dispelling wind clearing away summer-heat, circulation of qi promoting treating blood disorders, dampness removing is antipruritic.For headache due to common cold, laryngopharynx swelling and pain, heatstroke, acute gastroenteritis, dysentery, dysuria, oedema due to nephritis, leucorrhea, parch to black treating hematochezia, metrorrhagia.Traumatic injury is controlled in external, traumatic hemorrhage, miliaria, dermatitis, eczema, tinea pedis, multiple furuncle and phyma, venom.
Herba Ainsliaea Albotomentosae: bitter in the mouth, warm in nature.Expelling wind and removing dampness, dissipating blood stasis hemostasis, dispersing swelling and dissipating binds.Main air pain of dampness syndrome, blood stasis amenorrhea, traumatic injury, fracture swells and ache, traumatic hemorrhage, scrofula tuberculosis, wind and cold, breathes with cough." Yunnan Chinese herbal medicine " carries: " promoting flow of QI and blood, removing damp and stopping pain connect muscles and bones.Dispelling the wind and dampness pathogens arthralgia, traumatic injury, fracture, amenorrhea, allergic dermatitis.”
Folium Lantanae Camarae: bitter in the mouth, micro-sweet, cool in nature, poisonous.Return large intestine channel.Heat-clearing and toxic substances removing, removing obstruction for relieving pain.For cold and high fever, heat is not moved back for a long time, the tuberculosis of cervical lymph nodes, rheumatic ostalgia, stomachache, traumatic injury.Eczema is controlled in external, dermatitis, skin pruritus, furuncle and phyma, traumatic injury." Guangdong Chinese medicine " carries: " loose poison, applies large intestine infections carbuncle for dispelling wind for relieving itching, reducing swelling and alleviating pain.”
The present invention compared with prior art, has following beneficial effect:
1, external-applied ointment of the present invention has effect that heat-clearing and toxic substances removing, removing damp to relieve itching, dispelling wind nourish blood, obvious for treatment allergic dermatitis, abnormal flavour dermatitis, neurodermatitis, seborrheic dermatitis, drug eruption texts, for erythema, pimple, chap, the common dermatitis disease such as desquamation, little abscess, pruritus, tenderness and burning sensation has significant curative effect.
2, external-applied ointment of the present invention can be killed the various antibacterials in human body skin surface quickly and efficiently, the material of eliminating corruption, effectively promote optimization and the growth of epidermis cell, strengthen the plastid of epidermis cell, diminish inflammation, make the rapid rehabilitation of injured human body, have no side effect, therapeutic domain is wide, and cure rate is higher, with low cost, alleviate patient economy burden.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of external-applied ointment effective ingredient of the present invention are:
Herba Caraganae intermediae 75g Herba Droserae Lunatae 73g Alternanthera sessilis (L.) DC. 70g Herba seu Flos Convolvuli arvensis 65g
Cortex Sapii Radicis 64g Folium Phyllanthi 62g Folium pterocaryae stenopterae 57g Folium et Cacumen Broussonetiae Kazinoki 55g
Herba Clinopodii Polycephali 52g Herba galii veri 50g five-leaved chaste tree 45g Herba asparagi gobici 40g
The peaceful 37g Herba Ainsliaea Albotomentosae of the real 38g stone shepherd's purse of Herba chenopodii 31g Folium Lantanae Camarae 28g.
The preparation method of external-applied ointment of the present invention, comprises following processing step:
(1) Herba Droserae Lunatae, Herba seu Flos Convolvuli arvensis, Folium pterocaryae stenopterae and Herba Ainsliaea Albotomentosae are put into container, add the ethanol of 4 times of amounts, soak after 2~3 hours and filter, get filtrate, be condensed into the thick paste of relative density 1.20~1.22 at 60 DEG C, for subsequent use;
(2) Alternanthera sessilis (L.) DC., Herba Clinopodii Polycephali, stone shepherd's purse peace Folium Lantanae Camarae are cleaned up, mash, strand juice, with filtered through gauze twice, taking juice, for subsequent use;
(3) by real to Herba Caraganae intermediae, Cortex Sapii Radicis, Folium Phyllanthi, Folium et Cacumen Broussonetiae Kazinoki, Herba galii veri, five-leaved chaste tree, Herba asparagi gobici and the Herba chenopodii container of putting into, adding distil water boils and extracts 3 times, adds first 10-15 and doubly measures distilled water immersion 4-5 hour, and heated and boiled 3-4 hour, extracts; Add for the second time 8-10 and doubly measure distilled water heated and boiled 2-3 hour, extract; Add for the third time 6-8 and doubly measure distilled water heated and boiled 1~2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, concentrate and to be dried to dry extract for subsequent use;
(4) thick paste made above-mentioned steps (1)-(3), juice and dry extract are mixed, utilize modern advanced pharmacy science and technology, make ointment, obtain the external-applied ointment for the treatment of dermatitis of the present invention.
Usage and dosage: first dermatosis place is cleaned with disinfectant, be then coated with external-applied ointment 1-3 millimeters thick of the present invention on dermatosis surface, bind up with gauze and change medicine every day one time; Within 3 days, be a course for the treatment of, 1 course for the treatment of of the lighter, can fully recover severe one 3-4 the course for the treatment of.
Embodiment 2
Raw material composition and the weight of external-applied ointment effective ingredient of the present invention are:
Herba Caraganae intermediae 70g Herba Droserae Lunatae 68g Alternanthera sessilis (L.) DC. 65g Herba seu Flos Convolvuli arvensis 60g
Cortex Sapii Radicis 60g Folium Phyllanthi 57g Folium pterocaryae stenopterae 52g Folium et Cacumen Broussonetiae Kazinoki 40g
Herba Clinopodii Polycephali 47g Herba galii veri 45g five-leaved chaste tree 40g Herba asparagi gobici 37g
The peaceful 32g Herba Ainsliaea Albotomentosae of the real 34g stone shepherd's purse of Herba chenopodii 27g Folium Lantanae Camarae 22g.
The present embodiment external-applied ointment preparation method processing step and usage and dosage are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of external-applied ointment effective ingredient of the present invention are:
Herba Caraganae intermediae 65g Herba Droserae Lunatae 63g Alternanthera sessilis (L.) DC. 60g Herba seu Flos Convolvuli arvensis 56g
Cortex Sapii Radicis 55g Folium Phyllanthi 51g Folium pterocaryae stenopterae 48g Folium et Cacumen Broussonetiae Kazinoki 45g
Herba Clinopodii Polycephali 42g Herba galii veri 40g five-leaved chaste tree 37g Herba asparagi gobici 33g
The peaceful 27g Herba Ainsliaea Albotomentosae of the real 31g stone shepherd's purse of Herba chenopodii 24g Folium Lantanae Camarae 19g.
The present embodiment external-applied ointment preparation method processing step and usage and dosage are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of external-applied ointment effective ingredient of the present invention are:
Herba Caraganae intermediae 55g Herba Droserae Lunatae 53g Alternanthera sessilis (L.) DC. 50g Herba seu Flos Convolvuli arvensis 46g
Cortex Sapii Radicis 45g Folium Phyllanthi 41g Folium pterocaryae stenopterae 40g Folium et Cacumen Broussonetiae Kazinoki 35g
Herba Clinopodii Polycephali 33g Herba galii veri 30g five-leaved chaste tree 27g Herba asparagi gobici 25g
The peaceful 18g Herba Ainsliaea Albotomentosae of the real 22g stone shepherd's purse of Herba chenopodii 17g Folium Lantanae Camarae 13g.
The present embodiment external-applied ointment preparation method processing step and usage and dosage are identical with embodiment 1.
Clinical data:
1, case selection:
As the external-applied ointment for the treatment of dermatitis, select the routine clinical observation of dermatitis patients 400, patient is divided into two groups at random, treatment group 200 examples, wherein male's 97 examples, women's 103 examples, 8~63 years old age, 30.5 years old mean age, the course of disease 1~20 year, average 4.5 years; Severity extent: slight 49 examples, moderate 81 examples, severe 70 examples.Matched group 200 examples, wherein male's 99 examples, women's 101 examples, 9~61 years old age, 29.8 years old mean age, the course of disease 1~18 year, average 4.1 years; Severity extent: slight 52 examples, moderate 77 examples, severe 71 examples.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability, all keep on a diet on request for two groups.
2, medicament selection:
Treatment group patient is coated with and uses external-applied ointment of the present invention, is coated with external-applied ointment 1-3 millimeters thick of the present invention, changes medicine every day one time, within 3 days, is a course for the treatment of, uses continuously 2-4 the course for the treatment of; Matched group patient is coated with the millimeters thick with PIYANNING DING ointment 2-4, a course for the treatment of of twice, 3 day every day, uses continuously 2-4 the course for the treatment of.
3, efficacy determination:
(1) effective: skin pruritus disappears, it is normal that skin color recovers, can normal outdoor activity.
(2) effective: dermatitis patients pruritus is alleviated to some extent, and skin color recovers to some extent.
(3) invalid: through 2 course of therapy, dermatitis symptom does not have clear improvement.
4, result:
Be coated with in the treatment group of external-applied ointment of the present invention effective 128 examples, effective 60 examples, invalid 12 examples, total effective rate 94%.
Effective 57 examples in matched group, effective 71 examples, invalid 72 examples, total effective rate 64%.
Above result demonstration, the total effective rate for the treatment of group is apparently higher than matched group.
Model case is given an example:
1, Zhang, female, 16 years old, people from Hefei ,Anhui, face is suffered from seriousness folliculitis, and small pox pimple is linked to be sheet, dark red alternate, pox point is with purulent secretion, and patient is very painful, has used the whole bag of tricks and medicine all cannot cure, used afterwards the present invention to treat the external-applied ointment of dermatitis, and used after the course for the treatment of, sufferings alleviate, secretions disappears, and continues to use two courses for the treatment of, and pimple is shown in flat, red and swollen disappearance, dead bark comes off naturally thereupon, and it is normal that skin of face recovers.
2, Lee, female, 25 years old, people from Chengdu, Sichuan, 18 years old start, whole face and neck overgrow with acne, between several years, seek medical advice and medicine everywhere, the for oral administration outer thing of applying medicinal lotion or ointment of every treatment dermatitis all used, beauty parlor is also entered very much, due to medication and malpractice, result is not only cured, more and more serious on the contrary, whole face cicatrix, old speckle overlaps new speckle, skin of face is uneven, dark red alternate, patient is very painful, but have no way out, painting is treated after the external-applied ointment of dermatitis with the present invention, just take effect a course for the treatment of, four recoveries from illness course for the treatment of, black speck dead bark comes off, red pox disappears and calms down, skin repair is normal.
3, Song Nan, 34 years old, people from Yangzhou, Jiangsu, serious patients with seborrheic dermatitis, bilateral cheek, forehead, lower jaw morbidity, large stretch of blood red skin lesion, is covered with linen bran shape squama above, itches not only but also pain, and some places squama comes off after scratching and grabbing, oozing of blood incrustation.Before half a year, to our hospital, use after external-applied ointment of the present invention, treatment has had obvious effect, and skin is no longer greasy, and skin lesion place squama is moved back to the greatest extent, and ugly blood red also going down a lot, continues to use three courses for the treatment of on the face, and the state of an illness is cured, and skin recovers normally.
4, appoint certain, female, 53 years old, yiyang, hunan people, general dermatitis patients, visible big or small speckle before extremity, back, abdomen, illing skin is red and swollen as copper coin size, and exceed normal skin, very itch unbearably, once treated with antiallergic Western medicine before, medication disappears, drug withdrawal is sent out, Relapse rate outbreak, cannot effect a radical cure, and grab while itching black and blue all over, until hemorrhage ability is antipruritic, patient is very painful, has used the present invention to treat the external-applied ointment of dermatitis, uses take effect a course for the treatment of, after continuing to use three courses for the treatment of, fully recover, rear without recurrence.

Claims (5)

1. an external-applied ointment for the treatment of dermatitis, is characterized in that: raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
41~70 parts of 45~75 parts of Herba seu Flos Convolvuli arvensves of 48~78 parts of Alternanthera sessilis (L.) DC.s of 50~80 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
30~60 parts of 35~62 parts of Folium et Cacumen Broussonetiae Kazinoki of 38~65 parts of Folium pterocaryae stenopteraes of 40~69 parts of Folium Phyllanthi of Cortex Sapii Radicis
20~45 parts of 22~50 parts of Herba asparagi gobicis of 25~55 portions of five-leaved chaste trees of 28~57 parts of Herba galii veris of Herba Clinopodii Polycephali
10~30 parts of 13~35 parts of Folium Lantanae Camaraes of real 17~42 parts of peaceful 15~40 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii, make described external-applied ointment and comprise following processing step:
(1) Herba Droserae Lunatae, Herba seu Flos Convolvuli arvensis, Folium pterocaryae stenopterae and Herba Ainsliaea Albotomentosae are put into container, add the ethanol of 4 times of amounts, soak after 2~3 hours and filter, get filtrate, be condensed into the thick paste of relative density 1.20~1.22 at 60 DEG C, for subsequent use;
(2) Alternanthera sessilis (L.) DC., Herba Clinopodii Polycephali, stone shepherd's purse peace Folium Lantanae Camarae are cleaned up, mash, strand juice, with filtered through gauze twice, taking juice, for subsequent use;
(3) by real to Herba Caraganae intermediae, Cortex Sapii Radicis, Folium Phyllanthi, Folium et Cacumen Broussonetiae Kazinoki, Herba galii veri, five-leaved chaste tree, Herba asparagi gobici and the Herba chenopodii container of putting into, adding distil water boils and extracts 3 times, adds first 10-15 and doubly measures distilled water immersion 4-5 hour, and heated and boiled 3-4 hour, extracts; Add for the second time 8-10 and doubly measure distilled water heated and boiled 2-3 hour, extract; Add for the third time 6-8 and doubly measure distilled water heated and boiled 1~2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, concentrate and to be dried to dry extract for subsequent use;
(4) thick paste made above-mentioned steps (1)-(3), juice and dry extract are mixed, utilize modern advanced pharmacy science and technology, make ointment, obtain the external-applied ointment of described treatment dermatitis.
2. a kind of external-applied ointment for the treatment of dermatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
46~65 parts of 50~70 parts of Herba seu Flos Convolvuli arvensves of 53~73 parts of Alternanthera sessilis (L.) DC.s of 55~75 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
35~55 parts of 40~57 parts of Folium et Cacumen Broussonetiae Kazinoki of 41~62 parts of Folium pterocaryae stenopteraes of 45~64 parts of Folium Phyllanthi of Cortex Sapii Radicis
25~40 parts of 27~45 parts of Herba asparagi gobicis of 30~50 portions of five-leaved chaste trees of 33~52 parts of Herba galii veris of Herba Clinopodii Polycephali
13~28 parts of 17~31 parts of Folium Lantanae Camaraes of real 22~38 parts of peaceful 18~37 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
3. a kind of external-applied ointment for the treatment of dermatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
51~60 parts of 55~65 parts of Herba seu Flos Convolvuli arvensves of 58~68 parts of Alternanthera sessilis (L.) DC.s of 60~70 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
40~50 parts of 45~52 parts of Folium et Cacumen Broussonetiae Kazinoki of 46~57 parts of Folium pterocaryae stenopteraes of 50~60 parts of Folium Phyllanthi of Cortex Sapii Radicis
28~37 parts of 32~40 parts of Herba asparagi gobicis of 35~45 portions of five-leaved chaste trees of 38~47 parts of Herba galii veris of Herba Clinopodii Polycephali
16~22 parts of 22~27 parts of Folium Lantanae Camaraes of real 27~34 parts of peaceful 23~32 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
4. a kind of external-applied ointment for the treatment of dermatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described external-applied ointment effective ingredient are:
56 parts of 60 parts of Herba seu Flos Convolvuli arvensves of 63 parts of Alternanthera sessilis (L.) DC.s of 65 portions of Herba Droserae Lunataes of Herba Caraganae intermediae
45 parts of 48 parts of Folium et Cacumen Broussonetiae Kazinoki of 51 parts of Folium pterocaryae stenopteraes of 55 parts of Folium Phyllanthi of Cortex Sapii Radicis
33 parts of 37 parts of Herba asparagi gobicis of 40 portions of five-leaved chaste trees of 42 parts of Herba galii veris of Herba Clinopodii Polycephali
19 parts of 24 parts of Folium Lantanae Camaraes of the real 31 parts of peaceful 27 parts of Herba Ainsliaea Albotomentosaes of stone shepherd's purse of Herba chenopodii.
5. a preparation method for the treatment of the external-applied ointment of dermatitis as described in claim 1-4 any one, is characterized in that: comprise following processing step:
(1) Herba Droserae Lunatae, Herba seu Flos Convolvuli arvensis, Folium pterocaryae stenopterae and Herba Ainsliaea Albotomentosae are put into container, add the ethanol of 4 times of amounts, soak after 2~3 hours and filter, get filtrate, be condensed into the thick paste of relative density 1.20~1.22 at 60 DEG C, for subsequent use;
(2) Alternanthera sessilis (L.) DC., Herba Clinopodii Polycephali, stone shepherd's purse peace Folium Lantanae Camarae are cleaned up, mash, strand juice, with filtered through gauze twice, taking juice, for subsequent use;
(3) by real to Herba Caraganae intermediae, Cortex Sapii Radicis, Folium Phyllanthi, Folium et Cacumen Broussonetiae Kazinoki, Herba galii veri, five-leaved chaste tree, Herba asparagi gobici and the Herba chenopodii container of putting into, adding distil water boils and extracts 3 times, adds first 10-15 and doubly measures distilled water immersion 4-5 hour, and heated and boiled 3-4 hour, extracts; Add for the second time 8-10 and doubly measure distilled water heated and boiled 2-3 hour, extract; Add for the third time 6-8 and doubly measure distilled water heated and boiled 1~2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, concentrate and to be dried to dry extract for subsequent use;
(4) thick paste made above-mentioned steps (1)-(3), juice and dry extract are mixed, utilize modern advanced pharmacy science and technology, make ointment, obtain the external-applied ointment of described treatment dermatitis.
CN201310334404.XA 2013-08-02 2013-08-02 External use ointment used for treating dermatitis and preparation method thereof Expired - Fee Related CN103393916B (en)

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CN104000889B (en) * 2014-05-19 2015-07-08 刘新霞 Traditional Chinese medicine for treating neurodermatitis
CN104474410A (en) * 2014-11-26 2015-04-01 刘华锋 Traditional Chinese medicine composition for treating allergic dermatitis and preparation method thereof
CN104998035A (en) * 2015-07-23 2015-10-28 唐玲 External ointment for treating dermatosis and preparation method thereof
CN105055854A (en) * 2015-08-12 2015-11-18 王义金 Traditional Chinese medicine for treating neurodermatitis
CN105079292A (en) * 2015-08-22 2015-11-25 济南骄泰信息技术有限公司 Liquid preparation for treating dermatitis
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