CN103816387B - A kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia - Google Patents
A kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia Download PDFInfo
- Publication number
- CN103816387B CN103816387B CN201410083971.7A CN201410083971A CN103816387B CN 103816387 B CN103816387 B CN 103816387B CN 201410083971 A CN201410083971 A CN 201410083971A CN 103816387 B CN103816387 B CN 103816387B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- herba
- folium
- chinese medicinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention discloses a kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia, belong to the field of Chinese medicines; The raw material of external Chinese medicinal plaster effective ingredient of the present invention consists of: the Radix Angelicae Dahuricae, Fructus Psoraleae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Achyranthis Bidentatae, Caulis et Folium piperis, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Ramulus et Folium Debregeasiae Edulis, Fructus Ligustri Lucidi, Herba Reineckeae Carneae, Chai Gui, Flos Lonicerae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi), Radix Gentianae Macrophyllae, Radix Et Rhizoma Fagopyri Tatarici, Rhizoma Et Radix Notopterygii and Folium Nerviliae fordii; External Chinese medicinal plaster of the present invention selects high-quality Chinese crude drug formula, there is effect of eliminating dampness and dredging channels, eliminating stasis to stop pain, removing toxic substances and promoting subsidence of swelling, for treatment dystrophic hyperosteogeny and aplastic hyperosteogeny etc., all there is significant curative effect, manufacturing process is simple, and cost is low, easy to use, and short treating period, instant effect, without any side effects, Be very effective of enriching blood, total effective rate reaches 97.4%.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia.
Background technology
Bone matrix hyperplasia is soft tissue degeneration, the degeneration such as cartilage, intervertebral disc, ligament owing to forming joint, joint margins forms bony spur, synovial membrane plumpness waits change, and there is osteoclasia, cause insecondary hyperosteogeny, cause joint deformity, when being subject to abnormal load, cause arthralgia, a kind of disease of the symptoms such as limitation of activity.
Hyperosteogeny main manifestations is hyperosteogeny of cervical vertebra, lumbar vertebra hyperosteogeny and knee joint hyperosteogeny.Hyperosteogeny of cervical vertebra main manifestations is that there are strong sensation, limitation of activity in neck portion, cervical region activity has snap sound, and pain is often to shoulder and upper limb radiation, and hands and finger have the symptom such as numbness, electric shock sample sensation; Lumbar vertebra hyperosteogeny predilection site is the most common with waist three, waist four, often occur that lumbar vertebra and lumbar soft tissue are ached clinically, distending pain, stiff and tired sense, even bend over limited; The knee joint hyperosteogeny initial stage onset slow person gonalgia is not serious, there is sustainability dull pain, when temperature reduces, pain increases the weight of, relevant with climate change, comes into play after rising morning, long-time walking, strenuous exercise or sitting gonalgia when starting to walk that stands up is stiff, takes a turn for the better after slightly movable, upper and lower building difficulty, time downstairs, knee joint is felt like jelly, and easily falls down.Pain when having squatted, stiff, time serious, joint aches distending pain, limping is walked, and merge rheumatism patient redness and swelling of joints, deformity, function limitation, stretching activity in the wrong has snap sound, some patients visible joint hydrops, and there are obvious tumefaction, compression phenomena in local.
The method of current state internal therapy bone matrix hyperplasia has a lot, and as electric drug iontophoresis, ultraviolet therapy, western medicine, operative treatment etc., but limitation is all deposited in these treatments.Such as electric drug iontophoresis, galvanoiontophoresis method has given full play to the effect of medicine, but is liquid because importing medicine, volatile, and drug effect is not lasting, limits the therapeutic effect of the method; Ultraviolet has injury effect to human body skin; And doctor trained in Western medicine there is no effective medicine to this disease, often adopt anti symptom treatment, but facts have proved that these Therapeutic Method are all undesirable, just take stopgap measures and do not effect a permanent cure, the state of an illness easily recurs; Operative treatment operative treatment is not the first-selected therapy of hyperosteogeny, when select expectant treatment invalid and the state of an illness heavier, have a strong impact on minimal invasive treatment time, can operative treatment be considered.
Chinese medicine, as China's traditional medicine, has long research history in orthopaedics, uses Chinese medicine principle to treat hyperosteogeny and will be significant for it.
Summary of the invention
The invention provides a kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia; External Chinese medicinal plaster of the present invention selects high-quality Chinese crude drug formula, there is effect of eliminating dampness and dredging channels, eliminating stasis to stop pain, removing toxic substances and promoting subsidence of swelling, for treatment dystrophic hyperosteogeny and aplastic hyperosteogeny etc., all there is significant curative effect, manufacturing process is simple, and cost is low, easy to use, and short treating period, instant effect, without any side effects, Be very effective of enriching blood, total effective rate reaches 97.4%.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat an external Chinese medicinal plaster for bone matrix hyperplasia, raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 63 ~ 89 parts of Fructus Psoraleaes 60 ~ 86 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 52 ~ 78 parts of Radix Achyranthis Bidentataes 47 ~ 74 parts
Caulis et Folium piperis 47 ~ 73 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 43 ~ 72 parts of Ramulus et Folium Debregeasiae Edulis 43 ~ 72 parts of Fructus Ligustri Lucidi 39 ~ 66 parts
33 ~ 62 parts, Herba Reineckeae Carneae 38 ~ 65 parts of bavin osmanthus Flos Lonicerae 31 ~ 61 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 27 ~ 55 parts
Radix Gentianae Macrophyllae 26 ~ 52 parts of Radix Et Rhizoma Fagopyri Tatarici 23 ~ 48 portions of Rhizoma Et Radix Notopterygiis 20 ~ 41 parts of Folium Nerviliae fordiis 18 ~ 37 parts.
Raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 67 ~ 85 parts of Fructus Psoraleaes 64 ~ 82 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 56 ~ 74 parts of Radix Achyranthis Bidentataes 52 ~ 70 parts
Caulis et Folium piperis 51 ~ 70 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 49 ~ 67 parts of Ramulus et Folium Debregeasiae Edulis 47 ~ 67 parts of Fructus Ligustri Lucidi 43 ~ 61 parts
37 ~ 57 parts, Herba Reineckeae Carneae 42 ~ 61 parts of bavin osmanthus Flos Lonicerae 36 ~ 56 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 32 ~ 50 parts
Radix Gentianae Macrophyllae 30 ~ 48 parts of Radix Et Rhizoma Fagopyri Tatarici 27 ~ 45 portions of Rhizoma Et Radix Notopterygiis 24 ~ 37 parts of Folium Nerviliae fordiis 22 ~ 34 parts.
Raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 72 ~ 80 parts of Fructus Psoraleaes 69 ~ 77 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 61 ~ 69 parts of Radix Achyranthis Bidentataes 57 ~ 65 parts
Caulis et Folium piperis 56 ~ 64 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 54 ~ 62 parts of Ramulus et Folium Debregeasiae Edulis 52 ~ 60 parts of Fructus Ligustri Lucidi 48 ~ 56 parts
42 ~ 52 parts, Herba Reineckeae Carneae 47 ~ 55 parts of bavin osmanthus Flos Lonicerae 41 ~ 51 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 37 ~ 45 parts
Radix Gentianae Macrophyllae 35 ~ 43 parts of Radix Et Rhizoma Fagopyri Tatarici 32 ~ 40 portions of Rhizoma Et Radix Notopterygiis 27 ~ 32 parts of Folium Nerviliae fordiis 26 ~ 30 parts.
Raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 76 parts of Fructus Psoraleaes 73 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 65 parts of Radix Achyranthis Bidentataes 61 parts
Caulis et Folium piperis 60 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 58 parts of Ramulus et Folium Debregeasiae Edulis 56 parts of Fructus Ligustri Lucidi 52 parts
47 parts, Herba Reineckeae Carneae 51 parts of bavin osmanthus Flos Lonicerae 46 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 41 parts
Radix Gentianae Macrophyllae 39 parts of Radix Et Rhizoma Fagopyri Tatarici 36 portions of Rhizoma Et Radix Notopterygiis 30 parts of Folium Nerviliae fordiis 28 parts.
Treat a preparation method for the external Chinese medicinal plaster of bone matrix hyperplasia, comprise following processing step:
(1) container is put in the Radix Angelicae Dahuricae, Caulis et Folium piperis, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) and bavin osmanthus, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(2) Fructus Psoraleae, Flos Lonicerae, Radix Et Rhizoma Fagopyri Tatarici and Folium Nerviliae fordii are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.15, for subsequent use;
(3) Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Achyranthis Bidentatae, Fructus Ligustri Lucidi, Herba Reineckeae Carneae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Rhizoma Et Radix Notopterygii are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(4) cleaned by Ramulus et Folium Debregeasiae Edulis, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) cleaned by Radix Gentianae Macrophyllae decontamination, section, is placed in frying pan, with slow fire heating, fries and has focal spot to be advisable to coat tablets is micro-, take out airing, be placed in mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (5), make plaster, spread upon on medical disinfecting cotton, make plaster, obtain the external Chinese medicinal plaster for the treatment of bone matrix hyperplasia of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature; Attach to the lung and stomach meridians.Expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.Soft tissue contusion can be widely used in, hyperosteogeny, muscular strain, rheumatic myositis, fracture, costal chondritis, scapulohumeral periarthritis, the treatment of the diseases such as intercostal neuralgia.Modern medicine study confirms, the Radix Angelicae Dahuricae all has inhibitory action to escherichia coli, dysentery bacterium, Bacillus proteus, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera, Bacillus tuberculosis etc.
Fructus Psoraleae: acrid in the mouth, hardship, warm in nature; Return kidney, the heart, spleen, stomach, lung meridian.Reinforcing the kidney and supporting YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha.Cure mainly insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, sexual impotence essence, frequent micturition, the enuresis, failure of the kidney in receiving QI, dyspnea due to deficiency is more than, asthenia of both the spleen and kidney, stool chronic diarrhea, vitiligo, alopecia areata, psoriasis." beautiful Chinese catalpa medicine solution " carry: " warm water and soil, digestion diet, rise reach taste, convergence lingering diarrhea, seminal emission, leukorrhagia, drown many, just slide all cards.”
Radix achyranthis asperae (Herba Achyranthis Asperae): bitter in the mouth, pungent, cold in nature; Return liver, lung, urinary bladder channel.Blood circulation promoting and blood stasis dispelling, clearing away heat and expelling pathogen in the exterior.Cure cold heating, dysentery, malaria, laryngalgia, beriberi, gonorrhea, edema, traumatic injury." Guangxi Chinese medicinal herbal " carries: " diuresis, purifies the blood, sterilization.Control red-white dysentery, larynx disease, traumatic injury, strengthening bone and muscle, loose blood, pain relieving, reason beriberi.”
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down; Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignites descending, inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, lump in the abdomen, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain." detailed outline " carries: " control chronic malaria cold and heat, five types of stranguria hematuria, pains in the penis, dysentery, sore throat, aphtha, toothache, carbuncle malignant boil, traumatics fracture." modern medicine study confirmation, Radix Achyranthis Bidentatae has good protein assimilation and anti-inflammatory and analgesic effect.
Caulis et Folium piperis: acrid in the mouth, warm in nature; Return liver, spleen, small intestine meridian.Wind-damp dispelling, strong waist knee joint, kidney invigorating and YANG supporting, relieving cough and asthma, promoting blood circulation and stopping pain.Cure mainly anemofrigid-damp arthralgia, soreness of waist and knee joint, sexual impotence, cough and asthma, dysmenorrhea, treating swelling and pain by traumatic injury.
Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae): bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, benefiting stomach and stopping pain, dissipating blood stasis for subsidence of swelling.Control exogenous cough, pharyngalgia, aphtha of the mouth and tongue, vomiting and diarrhoea, dysentery, stomachache, swollen ulcer drug, traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " heat-clearing and toxic substances removing, eliminating stasis to stop pain.Control stomach and duodenum to burst hemorrhoid pain, treating swelling and pain by traumatic injury, neuralgia, toothache, acute gastroenteritis, bacillary dysentery, upper respiratory tract infection, pharyngalgia.”
Ramulus et Folium Debregeasiae Edulis: sweet in the mouth, cool in nature.To induce sweat heat clearing away, activating blood and eliminatng dampness.Control acute infantile convulsion wind, measles without adequate eruption, rheumatic arthritis, hemoptysis, dysentery, traumatic injury, skin infection." Chinese herbal medicine is commonly used in Sichuan " carries: " branch and leaf: expelling wind and cold.Control traumatic injury, measles is enclosed mass thoroughly and in women's abdomen.”
Fructus Ligustri Lucidi: sweet in the mouth, hardship, cool in nature; Return liver, kidney channel.Nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision." book on Chinese herbal medicine covers bamboo fish trap " carries: " the black palpus of hair color, strong rigidity of soft tissues power take wind of enriching blood more.”
Herba Reineckeae Carneae: sweet in the mouth, property is put down.Nourishing the lung to arrest cough, synthetism of dispeling the wind.For pulmonary tuberculosis, cough spitting of blood, chronic bronchitis, asthma, rheumatic arthritis; Traumatic injury is controlled in external, fracture." conventional Chinese herbal medicine handbook " carries, " nourishing the lung to arrest cough, the kidney invigorating synthetism.Control pulmonary tuberculosis cough, spit blood, asthma, chronic pyelonephritis, seminal emission, traumatic injury, fracture ".
Chai Gui: acrid in the mouth, sweet, warm in nature; Return liver, spleen channel.Promoting the flow of QI-blood by warming the meridian, promoting the circulation of QI to relieve pain.Cure mainly arthralgia due to cold-dampnes, epigastric pain, dysmenorrhea, traumatic injury.
Flos Lonicerae: sweet in the mouth, micro-hardship, cold in nature; Return lung, stomach, the heart, large intestine channel.Heat clearing away is eliminating evil, dispelling wind-heat, removing summer-heat blood poison.Modern pharmacological research shows, effective ingredient in Flos Lonicerae has antibacterial and antivirus action, obvious inhibitory action is had to staphylococcus aureus, Hemolytic streptococcus, dysentery bacterium, Bacillus typhi, meningococcus, Diplococcus pneumoniae, bacillus pyocyaneus and influenza virus etc., and can immunologic function be strengthened, antiinflammatory, antipyretic, there is obvious inhibitory action to inflammation.
Radix Piperis sarmentosi (Herba Piperis Sarmentosi): bitter in the mouth, warm in nature; GUIXIN, lung, spleen, large intestine channel.Expelling wind and cold, promoting the circulation of QI to relieve pain, active, detumescence.Main air is trembled with fear cough with asthma, rheumatic arthralgia, distension and fullness in the abdomen, dysentery, puerperal swelling of the feet, traumatic injury." the SHENGCAO property of medicine standby will " carries: " control toothache, wash rotten foot.”
Radix Gentianae Macrophyllae: acrid in the mouth, micro-hardship, property is put down; Return stomach, liver, gallbladder meridian.Wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, and infantile malnutrition generates heat.Modern medicine study confirms, the immersion of Radix Gentianae Macrophyllae ethanol all has inhibitory action to anthrax bacillus, staphylococcus, Bacillus typhi, pneumobacillus, dysentery bacterium, vibrio cholera in vitro. its water logging agent also has inhibitory action in various degree to common skin fungus in vitro.
Radix Et Rhizoma Fagopyri Tatarici: sweet in the mouth, property is put down, mild toxicity; Return spleen, stomach, large intestine channel.Spleen invigorating row is stagnant, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Cure mainly epigastric distending pain, dyspepsia, dysentery, lumbago and skelalgia, traumatic injury, carbuncle malignant boil, lyssodexis." Inner Mongol Chinese herbal medicine " carries: " removing damp and stopping pain, removing toxic substances and promoting subsidence of swelling, stomach invigorating.Control traumatic injury, lumbago and skelalgia, sore and toxic, dyspepsia.”
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature; Enter bladder, kidney channel.Loose exterior cold, wind-damp dispelling, sharp joint, pain relieving.Main affection of exogenous wind-cold, has a headache lossless, mimeograph cold-damp numbness, edema due to wind pathogen edema, sore swollen toxin.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.Induce sweat cold expelling, expelling wind and dampness, pain relieving." Japan hanako materia medica " carries: " control a wind cutting and gas, muscles and bones fist contraction, extremity are thin bad, and head revolves the red pain of eyes and fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times aqueous vapor, five kinds of strain and seven kinds of impairment, deficient cold air, joint ache, tonneau the five internal organs.”
Folium Nerviliae fordii: bitter in the mouth, sweet, property is put down.Clearing away lung-heat to relieve cough, spleen invigorating removing food stagnancy, sedation-analgesia, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, for pulmonary tuberculosis cough spitting of blood, bronchitis, infantile malnutrition, infantile pneumonia, psychosis, treating swelling and pain by traumatic injury, stomatitis, acute laryngitis, sore." Nanning City's medicine will " carries: " nourishing the lung to arrest cough antipyreticly clears away heart-fire.Control pulmonary tuberculosis, and separate carbon monoxide poisoning.”
The present invention compared with prior art, has following beneficial effect:
External Chinese medicinal plaster of the present invention selects high-quality Chinese crude drug formula, there is effect of eliminating dampness and dredging channels, eliminating stasis to stop pain, removing toxic substances and promoting subsidence of swelling, for treatment dystrophic hyperosteogeny and aplastic hyperosteogeny etc., all there is significant curative effect, manufacturing process is simple, and cost is low, easy to use, and short treating period, instant effect, without any side effects, Be very effective of enriching blood, total effective rate reaches 97.4%.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of external Chinese medicinal plaster effective ingredient of the present invention and weight are:
Radix Angelicae Dahuricae 85g Fructus Psoraleae 82g Radix achyranthis asperae (Herba Achyranthis Asperae) 74g Radix Achyranthis Bidentatae 70g
Caulis et Folium piperis 70g Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 67g Ramulus et Folium Debregeasiae Edulis 67g Fructus Ligustri Lucidi 61g
Herba Reineckeae Carneae 61g bavin osmanthus 57g Flos Lonicerae 56g Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 50g
Radix Gentianae Macrophyllae 48g Radix Et Rhizoma Fagopyri Tatarici 45g Rhizoma Et Radix Notopterygii 37g Folium Nerviliae fordii 34g.
The preparation method of external Chinese medicinal plaster of the present invention, comprises following processing step:
(1) container is put in the Radix Angelicae Dahuricae, Caulis et Folium piperis, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) and bavin osmanthus, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(2) Fructus Psoraleae, Flos Lonicerae, Radix Et Rhizoma Fagopyri Tatarici and Folium Nerviliae fordii are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.15, for subsequent use;
(3) Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Achyranthis Bidentatae, Fructus Ligustri Lucidi, Herba Reineckeae Carneae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Rhizoma Et Radix Notopterygii are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(4) cleaned by Ramulus et Folium Debregeasiae Edulis, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) cleaned by Radix Gentianae Macrophyllae decontamination, section, is placed in frying pan, with slow fire heating, fries and has focal spot to be advisable to coat tablets is micro-, take out airing, be placed in mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (5), make plaster, spread upon on medical disinfecting cotton, make plaster, obtain the external Chinese medicinal plaster for the treatment of bone matrix hyperplasia of the present invention.
Usage and dosage: external application, cleans affected part, dries, external plaster of the present invention is affixed on affected part, every day 1 time, and each 1 pastes, and within 5 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of external Chinese medicinal plaster effective ingredient of the present invention and weight are:
Radix Angelicae Dahuricae 80g Fructus Psoraleae 77g Radix achyranthis asperae (Herba Achyranthis Asperae) 69g Radix Achyranthis Bidentatae 65g
Caulis et Folium piperis 64g Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 62g Ramulus et Folium Debregeasiae Edulis 60g Fructus Ligustri Lucidi 56g
Herba Reineckeae Carneae 55g bavin osmanthus 52g Flos Lonicerae 51g Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 45g
Radix Gentianae Macrophyllae 43g Radix Et Rhizoma Fagopyri Tatarici 40g Rhizoma Et Radix Notopterygii 34g Folium Nerviliae fordii 30g.
The Chinese medicine plaster for external application ointment preparation processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of external Chinese medicinal plaster effective ingredient of the present invention and weight are:
Radix Angelicae Dahuricae 76g Fructus Psoraleae 73g Radix achyranthis asperae (Herba Achyranthis Asperae) 65g Radix Achyranthis Bidentatae 61g
Caulis et Folium piperis 60g Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 58g Ramulus et Folium Debregeasiae Edulis 56g Fructus Ligustri Lucidi 52g
Herba Reineckeae Carneae 51g bavin osmanthus 47g Flos Lonicerae 46g Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 41g
Radix Gentianae Macrophyllae 39g Radix Et Rhizoma Fagopyri Tatarici 36g Rhizoma Et Radix Notopterygii 30g Folium Nerviliae fordii 28g.
The Chinese medicine plaster for external application ointment preparation processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of external Chinese medicinal plaster effective ingredient of the present invention and weight are:
Radix Angelicae Dahuricae 72g Fructus Psoraleae 69g Radix achyranthis asperae (Herba Achyranthis Asperae) 61g Radix Achyranthis Bidentatae 57g
Caulis et Folium piperis 56g Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 54g Ramulus et Folium Debregeasiae Edulis 52g Fructus Ligustri Lucidi 48g
Herba Reineckeae Carneae 47g bavin osmanthus 42g Flos Lonicerae 41g Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 37g
Radix Gentianae Macrophyllae 35g Radix Et Rhizoma Fagopyri Tatarici 32g Rhizoma Et Radix Notopterygii 27g Folium Nerviliae fordii 26g.
The Chinese medicine plaster for external application ointment preparation processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of external Chinese medicinal plaster effective ingredient of the present invention and weight are:
Radix Angelicae Dahuricae 67g Fructus Psoraleae 64g Radix achyranthis asperae (Herba Achyranthis Asperae) 56g Radix Achyranthis Bidentatae 52g
Caulis et Folium piperis 51g Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 49g Ramulus et Folium Debregeasiae Edulis 47g Fructus Ligustri Lucidi 43g
Herba Reineckeae Carneae 42g bavin osmanthus 37g Flos Lonicerae 36g Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 32g
Radix Gentianae Macrophyllae 30g Radix Et Rhizoma Fagopyri Tatarici 27g Rhizoma Et Radix Notopterygii 24g Folium Nerviliae fordii 22g.
The Chinese medicine plaster for external application ointment preparation processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the external Chinese medicinal plaster for the treatment of bone matrix hyperplasia, select the routine clinical observation of hyperosteogeny patient 152 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 76 example, wherein male 36 example, women 40 example, 38 ~ 78 years old age, 58 years old mean age, the course of disease 1 ~ 11 year; Matched group 76 example, wherein male 37 example, women 39 example, 37 ~ 77 years old age, 57 years old mean age, the course of disease 1 ~ 10 year.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group uses external Chinese medicinal plaster of the present invention, external application, cleans affected part, dries, external plaster of the present invention is affixed on affected part, every day 1 time, and each 1 pastes, and within 5 days, is 1 course for the treatment of, takes 3 ~ 4 courses for the treatment of continuously, and 8 persons of being in a bad way follow the doctor's advice the meal with wine amount of adding.
Matched group takes diclofenac sodium enteric-coated tablets amine, oral: 1 time on the one, or 1 ~ 2 time on the one, or follows the doctor's advice, and takes after the meal, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: hyperosteogeny all disappears, and physical recovery is as usual.
(2) effective: hyperosteogeny symptom obviously disappears, and pain obviously alleviates.
(3) effective: hyperosteogeny symptom disappears substantially, and pain alleviates to some extent.
(4) invalid: by treating rear hyperosteogeny symptom without taking a turn for the better or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Lu, man, 39 years old, Xuancheng Profile, anhui Province people.The right knee of patient suffers from hyperosteogeny, acupuncture, take medicine treatment all without positive effect, the state of an illness increases the weight of gradually, hurt like hell.Introduce by friend and bring into use Chinese medicine external plaster of the present invention, after application, patient obviously feels that affected part generate heat, and the property of medicine is permeated, and after using 3 courses for the treatment of, patient takes action convenient, pain disappearance.
2, thunder, female, 42 years old, Fujian Longyan people.Patient's both arms joint suffers from bone matrix hyperplasia 5 years, fails to cure through multi-treatment, rear to our hospital, uses Chinese medicine external plaster of the present invention, after using 1 course for the treatment of, symptom alleviates to some extent, after continuing 2 courses for the treatment of of use, transference cure, hyperosteogeny is fully recovered, and follows up a case by regular visits to without recurrence after 1 year.
3, Zeng, man, 47 years old, people from Yichuan.Patient gives prominence to and sciatic nerve crush because suffering from hyperosteogeny companion lumbar vertebra point dish, rear to certain people's hospitalize, has spent nearly 10,000 yuans all without positive effect.To our hospital afterwards, after using 1 course for the treatment of of Chinese medicine external plaster of the present invention, health slightly improves, and after using 2 courses for the treatment of, cures, can be engaged in physical work, follow up a case by regular visits to and do not recur for 3 years.
4, leaf, female, 55 years old, people from Linyi, Shandong.Patient two knee hyperosteogeny for many years, with walking disorder time serious, taken multi-medicament and is used multiple plaster all to no effect.Patient is very dejected, introduces, uses Chinese medicine external plaster of the present invention by friend, and after pasting 1 course for the treatment of of medicine, patient is when walking, painless, and continue to paste 2 courses for the treatment of of medicine, admission examination display hypertrophy position is recovered normally.
5, section, man, 61 years old, people from Xuchang, Henan.Patient's joints of hand hyperosteogeny is serious, can't take care of oneself, and in many ways check that treatment is all without positive effect, patient is out of desperation.Rear patient introduces through doctor and uses Chinese medicine external plaster of the present invention, and after using 3 courses for the treatment of, hand activities is normal, and rule of life is normal.
6, Yuan, female, 74 years old, Hengyang, Hunan Province people.Bone matrix hyperplasia is suffered from 1 year in patient's both legs joint, and hurt like hell during walking, lives seriously influenced.After using 1 course for the treatment of of Chinese medicine external plaster of the present invention, the state of an illness takes a turn for the better to some extent, after continuing to use 2 courses for the treatment of of the present invention, cures, follows up a case by regular visits to and do not recur so far.
Claims (5)
1. treat an external Chinese medicinal plaster for bone matrix hyperplasia, it is characterized in that: raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 63 ~ 89 parts of Fructus Psoraleaes 60 ~ 86 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 52 ~ 78 parts of Radix Achyranthis Bidentataes 47 ~ 74 parts
Caulis et Folium piperis 47 ~ 73 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 43 ~ 72 parts of Ramulus et Folium Debregeasiae Edulis 43 ~ 72 parts of Fructus Ligustri Lucidi 39 ~ 66 parts
33 ~ 62 parts, Herba Reineckeae Carneae 38 ~ 65 parts of bavin osmanthus Flos Lonicerae 31 ~ 61 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 27 ~ 55 parts
Radix Gentianae Macrophyllae 26 ~ 52 parts of Radix Et Rhizoma Fagopyri Tatarici 23 ~ 48 portions of Rhizoma Et Radix Notopterygiis 20 ~ 41 parts of Folium Nerviliae fordiis 18 ~ 37 parts.
2. a kind of external Chinese medicinal plaster for the treatment of bone matrix hyperplasia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 67 ~ 85 parts of Fructus Psoraleaes 64 ~ 82 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 56 ~ 74 parts of Radix Achyranthis Bidentataes 52 ~ 70 parts
Caulis et Folium piperis 51 ~ 70 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 49 ~ 67 parts of Ramulus et Folium Debregeasiae Edulis 47 ~ 67 parts of Fructus Ligustri Lucidi 43 ~ 61 parts
37 ~ 57 parts, Herba Reineckeae Carneae 42 ~ 61 parts of bavin osmanthus Flos Lonicerae 36 ~ 56 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 32 ~ 50 parts
Radix Gentianae Macrophyllae 30 ~ 48 parts of Radix Et Rhizoma Fagopyri Tatarici 27 ~ 45 portions of Rhizoma Et Radix Notopterygiis 24 ~ 37 parts of Folium Nerviliae fordiis 22 ~ 34 parts.
3. a kind of external Chinese medicinal plaster for the treatment of bone matrix hyperplasia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 72 ~ 80 parts of Fructus Psoraleaes 69 ~ 77 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 61 ~ 69 parts of Radix Achyranthis Bidentataes 57 ~ 65 parts
Caulis et Folium piperis 56 ~ 64 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 54 ~ 62 parts of Ramulus et Folium Debregeasiae Edulis 52 ~ 60 parts of Fructus Ligustri Lucidi 48 ~ 56 parts
42 ~ 52 parts, Herba Reineckeae Carneae 47 ~ 55 parts of bavin osmanthus Flos Lonicerae 41 ~ 51 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 37 ~ 45 parts
Radix Gentianae Macrophyllae 35 ~ 43 parts of Radix Et Rhizoma Fagopyri Tatarici 32 ~ 40 portions of Rhizoma Et Radix Notopterygiis 27 ~ 32 parts of Folium Nerviliae fordiis 26 ~ 30 parts.
4. a kind of external Chinese medicinal plaster for the treatment of bone matrix hyperplasia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described external Chinese medicinal plaster effective ingredient are:
The Radix Angelicae Dahuricae 76 parts of Fructus Psoraleaes 73 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s 65 parts of Radix Achyranthis Bidentataes 61 parts
Caulis et Folium piperis 60 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 58 parts of Ramulus et Folium Debregeasiae Edulis 56 parts of Fructus Ligustri Lucidi 52 parts
47 parts, Herba Reineckeae Carneae 51 parts of bavin osmanthus Flos Lonicerae 46 Fen Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 41 parts
Radix Gentianae Macrophyllae 39 parts of Radix Et Rhizoma Fagopyri Tatarici 36 portions of Rhizoma Et Radix Notopterygiis 30 parts of Folium Nerviliae fordiis 28 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the external Chinese medicinal plaster of bone matrix hyperplasia, it is characterized in that: comprise following processing step:
(1) container is put in the Radix Angelicae Dahuricae, Caulis et Folium piperis, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) and bavin osmanthus, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(2) Fructus Psoraleae, Flos Lonicerae, Radix Et Rhizoma Fagopyri Tatarici and Folium Nerviliae fordii are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.15, for subsequent use;
(3) Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Achyranthis Bidentatae, Fructus Ligustri Lucidi, Herba Reineckeae Carneae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Rhizoma Et Radix Notopterygii are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(4) cleaned by Ramulus et Folium Debregeasiae Edulis, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) cleaned by Radix Gentianae Macrophyllae decontamination, section, is placed in frying pan, with slow fire heating, fries and has focal spot to be advisable to coat tablets is micro-, take out airing, be placed in mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (5), make plaster, spread upon on medical disinfecting cotton, make plaster, obtain the external Chinese medicinal plaster of described treatment bone matrix hyperplasia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410083971.7A CN103816387B (en) | 2014-03-09 | 2014-03-09 | A kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410083971.7A CN103816387B (en) | 2014-03-09 | 2014-03-09 | A kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103816387A CN103816387A (en) | 2014-05-28 |
| CN103816387B true CN103816387B (en) | 2016-03-09 |
Family
ID=50751867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410083971.7A Expired - Fee Related CN103816387B (en) | 2014-03-09 | 2014-03-09 | A kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103816387B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1413680A (en) * | 2002-10-21 | 2003-04-30 | 罗孝华 | Chinese medicine for treating hyperosteogeny |
| CN101007128A (en) * | 2007-01-29 | 2007-08-01 | 周新民 | Powder and salve for hyperplasia protrusion rehabilitation and its preparation method |
| CN103623249A (en) * | 2013-12-05 | 2014-03-12 | 韩友群 | Traditional Chinese medicine oral preparation for treating orthopedic disorders and preparation method thereof |
-
2014
- 2014-03-09 CN CN201410083971.7A patent/CN103816387B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1413680A (en) * | 2002-10-21 | 2003-04-30 | 罗孝华 | Chinese medicine for treating hyperosteogeny |
| CN101007128A (en) * | 2007-01-29 | 2007-08-01 | 周新民 | Powder and salve for hyperplasia protrusion rehabilitation and its preparation method |
| CN103623249A (en) * | 2013-12-05 | 2014-03-12 | 韩友群 | Traditional Chinese medicine oral preparation for treating orthopedic disorders and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103816387A (en) | 2014-05-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103393916A (en) | External use ointment used for treating dermatitis and preparation method thereof | |
| CN103705670A (en) | Traditional Chinese medicine for dispelling wind, eliminating dampness and relieving pain and preparation method thereof | |
| CN103463500A (en) | Medicament for treating cerebral hemorrhage | |
| CN105560748A (en) | Toxin drawing-out cream and preparation method thereof | |
| CN107375845A (en) | The topical composition and its application method that dispelling wind and eliminating dampness is clearing and activating the channels and collaterals | |
| CN103751626B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of sciatica | |
| CN103877427B (en) | A kind of Chinese medicinal plaster and preparation method for the treatment of cervical spondylosis | |
| CN103860946B (en) | A kind of external-applied ointment and preparation method for the treatment of traumatic injury | |
| CN103830482B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of apoplexy | |
| CN103830579B (en) | A kind of Chinese medicine ointment and preparation method for the treatment of cervical spondylosis | |
| CN104474428B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of spinal cord injury | |
| CN103816387B (en) | A kind of external Chinese medicinal plaster and preparation method for the treatment of bone matrix hyperplasia | |
| CN104398805A (en) | Traditional Chinese medicine preparation for treatment of lumbar muscle strain and preparation method thereof | |
| CN104887966A (en) | Traditional Chinese medicine preparation for treating lumbar muscle strain and preparation method thereof | |
| CN104491329A (en) | Traditional Chinese medicine preparation for treating osteoporosis and preparation method thereof | |
| CN103961555A (en) | Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof | |
| CN104147277A (en) | Traditional Chinese medicinal preparation for treating myasthenia gravis and preparation method | |
| CN103751624B (en) | A kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy | |
| CN103877390A (en) | Traditional-Chinese-medicine preparation for treating rheumatic fever and preparation method thereof | |
| CN103977260B (en) | A kind of medicine for treating sciatica and preparation method | |
| CN103877356B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of myocardial infarction | |
| CN106138629A (en) | The medicine of a kind of cure scapulohumeral periarthritis and preparation method | |
| CN105560753A (en) | Medicine for curing scapulohumeral periarthritis and preparing method | |
| CN106420999A (en) | Blood-activating decoction for treating joint degenerative changes | |
| CN104474353A (en) | Medicine for treating myasthenia gravis and preparation method of medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Binxun Inventor after: Zhang Ning Inventor before: Qiu Guangxue |
|
| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170615 Address after: 168 Zhaoyuan people's Hospital, Yingbin Road, Yantai, Shandong 265400, Zhaoyuan, China Patentee after: Wang Binxun Address before: 262200 Shandong city of Weifang Province Zhucheng City Dongguan Street No. 168, Zhucheng City Hospital of traditional Chinese Medicine Patentee before: Qiu Guangxue |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160309 Termination date: 20190309 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |