CN115006473A - Traditional Chinese medicine liquor for treating arthralgia and preparation method thereof - Google Patents
Traditional Chinese medicine liquor for treating arthralgia and preparation method thereof Download PDFInfo
- Publication number
- CN115006473A CN115006473A CN202210417026.0A CN202210417026A CN115006473A CN 115006473 A CN115006473 A CN 115006473A CN 202210417026 A CN202210417026 A CN 202210417026A CN 115006473 A CN115006473 A CN 115006473A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- chinese medicine
- liquor
- treating arthralgia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 69
- 208000006820 Arthralgia Diseases 0.000 title claims abstract description 49
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 244000060545 Wikstroemia viridiflora Species 0.000 claims abstract description 28
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 claims abstract description 22
- 244000107975 Strychnos nux-vomica Species 0.000 claims abstract description 21
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 20
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims abstract description 19
- 235000003097 Artemisia absinthium Nutrition 0.000 claims abstract description 19
- 240000001851 Artemisia dracunculus Species 0.000 claims abstract description 19
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims abstract description 19
- 239000001138 artemisia absinthium Substances 0.000 claims abstract description 19
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 19
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 18
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 18
- 241000195954 Lycopodium clavatum Species 0.000 claims abstract description 17
- 241000913745 Spatholobus Species 0.000 claims abstract description 17
- 244000018716 Impatiens biflora Species 0.000 claims abstract description 16
- 235000015912 Impatiens biflora Nutrition 0.000 claims abstract description 16
- 235000018735 Sambucus canadensis Nutrition 0.000 claims abstract description 16
- 235000005155 Tanacetum balsamita Nutrition 0.000 claims abstract description 16
- 235000007123 blue elder Nutrition 0.000 claims abstract description 16
- 235000007124 elderberry Nutrition 0.000 claims abstract description 16
- 235000008995 european elder Nutrition 0.000 claims abstract description 16
- 241000173529 Aconitum napellus Species 0.000 claims abstract description 14
- 241000209035 Ilex Species 0.000 claims abstract description 14
- 235000003332 Ilex aquifolium Nutrition 0.000 claims abstract description 14
- 235000002296 Ilex sandwicensis Nutrition 0.000 claims abstract description 14
- 235000002294 Ilex volkensiana Nutrition 0.000 claims abstract description 14
- 241000208682 Liquidambar Species 0.000 claims abstract description 14
- 235000006552 Liquidambar styraciflua Nutrition 0.000 claims abstract description 14
- 241000316342 Taxillus Species 0.000 claims abstract description 14
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 14
- 210000000582 semen Anatomy 0.000 claims description 32
- 239000000463 material Substances 0.000 claims description 28
- 238000002791 soaking Methods 0.000 claims description 23
- 238000002156 mixing Methods 0.000 claims description 19
- 239000002994 raw material Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 241000208829 Sambucus Species 0.000 claims description 15
- 239000004576 sand Substances 0.000 claims description 15
- 235000002566 Capsicum Nutrition 0.000 claims description 13
- 239000006002 Pepper Substances 0.000 claims description 13
- 241000722363 Piper Species 0.000 claims description 13
- 235000016761 Piper aduncum Nutrition 0.000 claims description 13
- 235000017804 Piper guineense Nutrition 0.000 claims description 13
- 235000008184 Piper nigrum Nutrition 0.000 claims description 13
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 10
- 241000180649 Panax notoginseng Species 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 10
- 244000089698 Zanthoxylum simulans Species 0.000 claims description 9
- 238000001035 drying Methods 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 9
- 239000012535 impurity Substances 0.000 claims description 9
- 238000010298 pulverizing process Methods 0.000 claims description 9
- 241001022083 Flemingia Species 0.000 claims description 7
- 244000131415 Zanthoxylum piperitum Species 0.000 claims description 4
- 235000008853 Zanthoxylum piperitum Nutrition 0.000 claims description 4
- 235000019640 taste Nutrition 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 39
- 208000002193 Pain Diseases 0.000 abstract description 37
- 230000036407 pain Effects 0.000 abstract description 37
- 230000008961 swelling Effects 0.000 abstract description 19
- 229940079593 drug Drugs 0.000 abstract description 18
- 210000004369 blood Anatomy 0.000 abstract description 14
- 239000008280 blood Substances 0.000 abstract description 14
- 210000000988 bone and bone Anatomy 0.000 abstract description 13
- 210000002435 tendon Anatomy 0.000 abstract description 11
- 238000005728 strengthening Methods 0.000 abstract description 10
- 230000001717 pathogenic effect Effects 0.000 abstract description 9
- 206010061218 Inflammation Diseases 0.000 abstract description 6
- 230000004054 inflammatory process Effects 0.000 abstract description 6
- 210000001519 tissue Anatomy 0.000 abstract description 6
- 230000035699 permeability Effects 0.000 abstract description 5
- 230000001954 sterilising effect Effects 0.000 abstract description 5
- 239000003440 toxic substance Substances 0.000 abstract description 5
- 230000003467 diminishing effect Effects 0.000 abstract description 4
- 239000012466 permeate Substances 0.000 abstract description 3
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 3
- 230000009471 action Effects 0.000 abstract description 2
- 231100000167 toxic agent Toxicity 0.000 abstract description 2
- 244000151637 Sambucus canadensis Species 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 description 14
- 210000003734 kidney Anatomy 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 230000001737 promoting effect Effects 0.000 description 9
- 201000010099 disease Diseases 0.000 description 8
- 208000014674 injury Diseases 0.000 description 8
- 210000003127 knee Anatomy 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 230000008736 traumatic injury Effects 0.000 description 8
- 230000017531 blood circulation Effects 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 7
- 201000003068 rheumatic fever Diseases 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 7
- 231100000331 toxic Toxicity 0.000 description 7
- 230000002588 toxic effect Effects 0.000 description 7
- 230000003203 everyday effect Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 208000008035 Back Pain Diseases 0.000 description 5
- 208000004880 Polyuria Diseases 0.000 description 5
- 208000025747 Rheumatic disease Diseases 0.000 description 5
- 230000035619 diuresis Effects 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 230000000552 rheumatic effect Effects 0.000 description 5
- 241000721047 Danaus plexippus Species 0.000 description 4
- 208000032843 Hemorrhage Diseases 0.000 description 4
- 208000012659 Joint disease Diseases 0.000 description 4
- 206010050031 Muscle strain Diseases 0.000 description 4
- 206010041591 Spinal osteoarthritis Diseases 0.000 description 4
- 230000003213 activating effect Effects 0.000 description 4
- 235000019658 bitter taste Nutrition 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 208000008930 Low Back Pain Diseases 0.000 description 3
- 206010027514 Metrorrhagia Diseases 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 208000036319 cervical spondylosis Diseases 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 210000002216 heart Anatomy 0.000 description 3
- 230000001976 improved effect Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- MWUXSHHQAYIFBG-UHFFFAOYSA-N nitrogen oxide Inorganic materials O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 3
- 231100000862 numbness Toxicity 0.000 description 3
- 238000000554 physical therapy Methods 0.000 description 3
- 239000011505 plaster Substances 0.000 description 3
- 208000005801 spondylosis Diseases 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 208000004044 Hypesthesia Diseases 0.000 description 2
- 206010050296 Intervertebral disc protrusion Diseases 0.000 description 2
- 208000019255 Menstrual disease Diseases 0.000 description 2
- 206010028372 Muscular weakness Diseases 0.000 description 2
- 206010028836 Neck pain Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 206010034464 Periarthritis Diseases 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- RRKTZKIUPZVBMF-IBTVXLQLSA-N brucine Chemical compound O([C@@H]1[C@H]([C@H]2C3)[C@@H]4N(C(C1)=O)C=1C=C(C(=CC=11)OC)OC)CC=C2CN2[C@@H]3[C@]41CC2 RRKTZKIUPZVBMF-IBTVXLQLSA-N 0.000 description 2
- RRKTZKIUPZVBMF-UHFFFAOYSA-N brucine Natural products C1=2C=C(OC)C(OC)=CC=2N(C(C2)=O)C3C(C4C5)C2OCC=C4CN2C5C31CC2 RRKTZKIUPZVBMF-UHFFFAOYSA-N 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 208000034783 hypoesthesia Diseases 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 230000036473 myasthenia Effects 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 201000008482 osteoarthritis Diseases 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 235000019633 pungent taste Nutrition 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- QMGVPVSNSZLJIA-FVWCLLPLSA-N strychnine Chemical compound O([C@H]1CC(N([C@H]2[C@H]1[C@H]1C3)C=4C5=CC=CC=4)=O)CC=C1CN1[C@@H]3[C@]25CC1 QMGVPVSNSZLJIA-FVWCLLPLSA-N 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 208000004611 Abdominal Obesity Diseases 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 241001671653 Aconitum carmichaelii Species 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010002556 Ankylosing Spondylitis Diseases 0.000 description 1
- 241000205585 Aquilegia canadensis Species 0.000 description 1
- 240000006891 Artemisia vulgaris Species 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 206010005963 Bone formation increased Diseases 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- 235000007862 Capsicum baccatum Nutrition 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 206010065941 Central obesity Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 206010020112 Hirsutism Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 241000720991 Illicium Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000003618 Intervertebral Disc Displacement Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010033425 Pain in extremity Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000000474 Poliomyelitis Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241001050737 Sambucus williamsii Species 0.000 description 1
- 208000008765 Sciatica Diseases 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 206010040925 Skin striae Diseases 0.000 description 1
- 208000026137 Soft tissue injury Diseases 0.000 description 1
- 241001300193 Speranskia Species 0.000 description 1
- 241001279009 Strychnos toxifera Species 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000001728 capsicum frutescens Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000009982 effect on human Effects 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 206010025005 lumbar spinal stenosis Diseases 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 230000003821 menstrual periods Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 208000021722 neuropathic pain Diseases 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000012454 non-polar solvent Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 208000027753 pain disease Diseases 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000000276 sedentary effect Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 208000005198 spinal stenosis Diseases 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229960005453 strychnine Drugs 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 201000004595 synovitis Diseases 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The application provides traditional Chinese medicine liquor for treating arthralgia and a preparation method thereof, and relates to the field of traditional Chinese medicines. A traditional Chinese medicine medicated wine for treating arthralgia comprises: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of common clubmoss herb, 120-300 parts of beautiful sweetgum fruit, 120-300 parts of Chinese taxillus twig, 120-300 parts of nux vomica, 120-300 parts of common monkshood mother root, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of jack-in-the-palm and 80-250 parts of ovateleaf holly bark. The medicated liquor has rapid drug action and strong permeability, can rapidly permeate into pain parts of patients, and has effects of removing toxic substance, removing blood stasis, diminishing inflammation, sterilizing, dispelling pathogenic wind, removing dampness, strengthening tendons and bones, relieving swelling and pain, and repairing damaged tissue and cells.
Description
Technical Field
The application relates to the field of traditional Chinese medicines, and particularly relates to traditional Chinese medicine liquor for treating arthralgia and a preparation method thereof.
Background
Most people have more and more body problems of rheumatic arthralgia and arthralgia caused by excessive strain, cervical spondylosis oppresses nerves, unsmooth blood circulation, unsmooth qi and blood and the like, and particularly middle-aged and old people suffer from more and more body pain diseases such as cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, osteoarthritis, rheumatic arthritis, synovitis, traumatic injury, joint neuropathic pain and the like. In addition, due to the acceleration of the modernization process and the popularization of smart phones, many young people lean their heads for a long time to play mobile phones and computers, so that joint diseases, particularly cervical vertebra and lumbar vertebra, are caused to occur to different degrees of cervical vertebra, lumbar vertebra and shoulder elbows, and various joint disease diseases develop gradually from the old to the middle.
The traditional Chinese medicine considers that most of arthralgia diseases are caused by external attack of exogenous pathogenic factors such as meridian occlusion, wind cold and dampness, deficiency and obstruction of qi and blood, soft tissue injury and the like. The meridians and collaterals are externally connected with the skin and muscle striae and internally connected with the five zang organs and six nods to connect all parts of the body, so that the human body becomes an organic unity. At present, the treatment method for arthralgia is diversified, and mainly comprises drug analgesia, physical therapy, traditional physical therapy and treatment of traditional Chinese medicines. If hormone is used for treatment, the toxic and side effects are great, and serious complications such as central obesity, hirsutism, gastrorrhagia and the like are easy to occur after long-term administration. The traditional Chinese medicine has no toxic or side effect, can achieve the effect of treating both symptoms and root causes, is well received by the majority of patients, and achieves certain effect by taking oral medicinal liquor or decoction, external medicinal liquor, external plaster and the like. At present, most of the medicines for treating the joint diseases in the market are plaster, and the plaster has great side effect and unobvious effect on the treatment of the joint diseases and has great damage to human skins. The medicated liquor has effects in promoting local blood circulation, relieving muscle spasm, improving oxygen supply of local tissue, promoting metabolism, and relieving inflammation. Therefore, it is very important to develop a Chinese medicinal composition which has quick response, simple and safe use, no irritation to skin, no side effect on human body and can effectively treat various arthralgia.
Disclosure of Invention
The application aims to provide the traditional Chinese medicine medicinal liquor for treating arthralgia, and the medicinal liquor has the functions of drawing out toxin, dissipating blood stasis, diminishing inflammation, sterilizing, dispelling wind, removing dampness, strengthening tendons and bones, relieving swelling and pain and repairing damaged tissues and cells.
Another objective of the present application is to provide a method for preparing a traditional Chinese medicine medicated wine for treating arthralgia, which can effectively extract effective components from medicinal materials, so that the medicinal materials can exert the maximum efficacy.
The technical problem to be solved by the application is solved by adopting the following technical scheme.
On one hand, the embodiment of the application provides traditional Chinese medicine liquor for treating arthralgia, which comprises white spirit and the following raw materials in parts by weight: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of common clubmoss herb, 120-300 parts of beautiful sweetgum fruit, 120-300 parts of Chinese taxillus twig, 120-300 parts of nux vomica, 120-300 parts of common monkshood mother root, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of jack-in-the-palm and 80-250 parts of ovateleaf holly bark.
On the other hand, the embodiment of the application provides a preparation method of traditional Chinese medicine medicated wine for treating arthralgia, which comprises the following steps:
pretreating medicinal materials: parching semen Strychni with sand; soaking radix Aconiti in water, rinsing until the radix Aconiti is tasted spicy, taking out, mixing semen Strychni parched with sand and rinsed radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, caulis et folium Gaultheriae Yunnanensis, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, Notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
preparing medicinal liquor: mixing the dried raw materials with the Chinese liquor, sealing and soaking, filtering to remove impurities, distilling the filtered liquor to obtain an extract, extracting the extract, sealing and storing to obtain the medicinal liquor.
Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:
the traditional Chinese medicine composition is prepared according to external treatment of internal diseases in traditional Chinese medicine, and the traditional Chinese medicine considers that the internal diseases are both wind cold dampness and heat; or traumatic injury; the swelling and pain due to qi stagnation and blood stasis are all caused by the obstruction of qi and blood channels. In the traditional Chinese medicine composition, the wormwood is used for dredging twelve meridians and removing three yin, has the effects of dispelling wind and removing dampness, clearing and activating the channels and collaterals, and reducing swelling and dissipating stagnation, is pure yang in property, can penetrate all the meridians to remove various diseases by virtue of moxibustion fire, and is a monarch drug; the elderberry, the garden balsam stem, the suberect spatholobus stem and the common clubmoss herb are mutually matched, can expel wind and remove dampness, relax muscles and tendons, promote blood circulation, relieve swelling and stop pain, is a ministerial drug, and can be used for joint ache and difficulty in flexion and extension by matching with a monarch drug; fructus Lipuidambaris, herba Taxilli, semen Strychni, radix Aconiti and Indian stringbush root as adjuvant drugs, wherein fructus Lipuidambaris and Indian stringbush root are matched with each other for clearing heat and detoxicating, inducing diuresis and dredging channels; the nux vomica and the radix aconiti are mutually matched, so that the effects of dredging collaterals, relieving pain, dissipating stagnation and reducing swelling can be achieved; herba Taxilli has effects of nourishing liver and kidney, and strengthening tendons and bones; can be used in combination with principal drugs for treating rheumatic arthralgia, soreness of waist and knees, and weakness of tendons and bones; pseudo-ginseng, Qianjin and Ilicis Rotundae are guiding drugs, wherein the pseudo-ginseng and Ilicis Rotundae have the effects of clearing heat, promoting diuresis, relieving swelling and pain, and the Ilicis Rotundae can dispel wind-damp, supplement qi and blood, strengthen waist and knees; the combination of the medicines can dredge the channels and activate blood circulation, so that the medicinal components in the medicinal materials pass through the twelve channels and travel throughout the whole body, and the medicinal liquor with super-strong permeability can quickly permeate to the pain part of a patient to directly reach the focus. The medicinal liquor has the advantages of having super strong permeability, being capable of rapidly permeating to the pain affected part of a patient, drawing out poison and dissipating blood stasis, diminishing inflammation and sterilizing, dispelling wind and removing dampness, strengthening tendons and bones, relieving swelling and pain, and repairing damaged tissues and cells, thereby achieving the rehabilitation in the true sense. The Chinese medicinal composition has reasonable compatibility, and can be used for treating various diseases such as arthralgia, soreness of waist and knees, myasthenia of bones and muscles, rheumatic arthritis, lumbago and skelalgia, and lumbar muscle strain.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to specific examples.
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of common clubmoss herb, 120-300 parts of beautiful sweetgum fruit, 120-300 parts of Chinese taxillus twig, 120-300 parts of nux vomica, 120-300 parts of common monkshood mother root, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of jack-bud and 80-250 parts of ovate leaf holly bark.
Mugwort, bitter and pungent in flavor, warm in nature, enters spleen, liver and kidney. Has effects in warming channels, eliminating dampness, expelling cold, stopping bleeding, relieving inflammation, relieving asthma, relieving cough, preventing miscarriage, and resisting allergy. Menoxenia, dysmenorrhea, abdominal pain, abortion, metrorrhagia, and can be used for the treatment of rheumatic arthritis, headache, and endogenous wind in the month. The nature of pure yang can return to the yang of the most deficient one, unblock twelve meridians, go through three yin meridians, regulate qi and blood, expel cold and dampness, warm uterus, and remove all diseases by the moxibustion fire.
Sambucus williamsii Hance enters liver meridian. Sweet and bitter in flavor and neutral in nature. Has effects in promoting reunion of bone, promoting blood circulation, relieving pain, dispelling pathogenic wind, and removing dampness. Can be used for treating fracture, traumatic injury, rheumatic arthritis, gout, Kaschin-Beck disease, acute nephritis, and chronic nephritis; it is used externally to treat bleeding due to wound.
Speranskia herb enters liver and kidney meridians. Pungent and bitter with warm nature. Has little toxicity. Has effects in dispelling pathogenic wind, removing dampness, removing toxic substance and relieving pain. Can be used for treating rheumatic arthralgia; it is used externally to treat sore and ulcer with swelling and toxin.
Spatholobus stem enters liver and kidney meridians. Bitter and sweet in taste and warm in nature. Has effects in tonifying blood, promoting blood circulation, and dredging meridians. Can be used for treating menoxenia, blood deficiency, sallow complexion, numbness, paralysis, and rheumatalgia.
Lycopodium clavatum enters liver, spleen and kidney meridians. Slightly bitter and pungent taste, warm nature. Has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles and activating collaterals. Can be used for treating joint pain and difficulty in flexion and extension.
Lu Lian Zi enters liver and kidney meridians. Bitter taste and mild nature. Has the effects of dispelling pathogenic wind, activating collaterals, inducing diuresis and dredging channels. Can be used for treating arthralgia, numbness, spasm, edema, distention and amenorrhea.
Sang Ji Sheng enters liver and kidney meridians. Bitter and sweet in taste and neutral in nature. Has effects in nourishing liver and kidney, strengthening muscle and bone, dispelling pathogenic wind and dampness, and preventing fetal contraction. Can be used for treating rheumatalgia, soreness of waist and knees, weakness of tendons and bones, metrorrhagia, metrostaxis, and pregnant hemorrhage; hypertension is caused.
Semen Strychni enters liver and spleen meridians. Bitter taste and warm nature; it is toxic. Has effects in dredging collaterals, relieving pain, resolving hard mass and relieving swelling. Can be used for treating rheumatism, numbness, paralysis, traumatic injury, carbuncle, cellulitis, and swelling and pain; sequela of poliomyelitis, rheumatoid arthralgia.
Sichuan aconite root, radix Aconiti Praeparata enters heart, liver, kidney and spleen meridians. Pungent, bitter and hot in flavor; it is toxic. Has the effects of dispelling pathogenic wind, removing dampness, warming channels and relieving pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia, and pain due to anesthesia.
Returning the Indian stringbush to the heart; a lung; the small intestine channel. Bitter and pungent taste; cold in nature; is toxic. Has the functions of clearing away heat and toxic material; resolving phlegm and resolving masses; relieving swelling and pain. Carbuncle and sore; scrofula; rheumatalgia; traumatic injury; bite by snake and insect
Notoginseng radix enters liver and stomach meridians. Sweet, slightly bitter and warm in nature. Has the effects of removing blood stasis, stopping bleeding, relieving swelling and relieving pain. Can be used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracico-abdominal pain, and traumatic swelling and pain.
Qian Dian enters lung, kidney and bladder meridians. Sweet taste, slightly warm and mild nature. Has effects in dispelling pathogenic wind, removing dampness, and strengthening waist and knees. Can be used for treating rheumatic arthritis, lumbago, leg pain, lumbar muscle strain, leucorrhea, and traumatic injury.
Ovate leaf holly bark enters lung, liver and large intestine meridians. Is bitter in taste; is cold in nature. Has the functions of clearing away heat and toxic material; removing dampness; relieving pain. Mainly treating cold and fever; swollen and sore throat; stomach pain; diarrhea due to summer-heat; jaundice; dysentery; traumatic injury; rheumatic arthralgia; eczema; sores and furuncles.
In some embodiments of the application, the traditional Chinese medicine wine for treating arthralgia further comprises 300-600 parts of pepper and 300-600 parts of zanthoxylum piperitum. The Chinese prickly ash and the red bell pepper are matched with each other, so that the effects of strengthening and stimulating surface skin, expanding pores and promoting quick absorption of liquid medicine are achieved.
In some embodiments of the application, the traditional Chinese medicine wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 480-520 parts of wormwood, 250-300 parts of elderberry, 250-300 parts of garden balsam stem, 250-300 parts of suberect spatholobus stem, 250-300 parts of common clubmoss herb, 180-250 parts of beautiful sweetgum fruit, 180-250 parts of Chinese taxillus twig, 180-250 parts of nux vomica, 180-250 parts of common monkshood mother root, 180-250 parts of Indian stringbush root, 140-250 parts of pseudo-ginseng, 140-250 parts of jack-in-the-mouth, 140-250 parts of ovate holly bark, 350-550 parts of pepper and 350-550 parts of red cluster pepper.
In some embodiments of the application, the traditional Chinese medicine wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 500 parts of wormwood, 250 parts of elderberry, 250 parts of garden balsam stem, 250 parts of suberect spatholobus stem, 250 parts of common clubmoss herb, 250 parts of beautiful sweetgum fruit, 250 parts of Chinese taxillus twig, 250 parts of nux vomica, 250 parts of common monkshood mother root, 250 parts of Indian stringbush root, 250 parts of pseudo-ginseng, 250 parts of philippine flemingia root, 250 parts of ovate leaf holly bark, 500 parts of Chinese prickly ash and 500 parts of red cluster pepper.
In some embodiments of the present application, the mass ratio of the white spirit to the raw materials is 1: 6-8. According to the proportion, the effective components in the medicinal materials can be better and more quickly dissolved out, the amount of the white spirit is large enough, and the medicinal liquor also has a sterilization effect, so that the medicinal materials are in a sterile environment, and the medicinal liquor can be better stored.
In some embodiments of the present application, the alcohol content of the white spirit is 45-60 degrees. The liquor is a good solvent, is easy to enter tissue cells of medicinal materials, can dissolve most of water-soluble substances in the medicinal materials and organic substances which cannot be dissolved by water and need to be dissolved by a non-polar solvent, can quickly dissolve out active ingredients in the medicinal materials by high-degree liquor, but the liquor degree is not higher, the better, and is suitable for 45-60 degrees.
A preparation method of traditional Chinese medicine medicinal liquor for treating arthralgia comprises the following steps:
parching semen Strychni with sand; soaking radix Aconiti in water, rinsing until the radix Aconiti is tasted spicy, taking out, mixing semen Strychni parched with sand and rinsed radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, caulis et folium Gaultheriae Yunnanensis, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, Notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with the white spirit, soaking, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution, sealing and storing to obtain the medicinal liquor.
In some embodiments of the present application, the soaking time is 10 to 15 days. The soaking is to dissolve the effective substances in the medicinal materials into the white spirit for a short time, and the effective substances in the medicinal materials are completely dissolved into the white spirit; the drug effect is affected by too long soaking time, so that the soaking time is suitable for 10 to 15 days.
In some embodiments of the present application, the storage temperature is 25 to 30 ℃. Under the condition, the medicinal liquor is stored for a longer time and is not easy to deteriorate.
In some embodiments of the present application, the sand-frying temperature is 160-250 ℃ and the sand-frying time is 4-15 min. The sand frying temperature and the sand frying time are controlled, so that the content of toxic substances in the processed nux vomica products can be well controlled. Under the condition, the nux vomica is stir-fried by sand, the main toxic substances strychnine and brucine of the nux vomica are converted into nitrogen oxides of Ninghe brucine with low toxicity, similar curative effect and better pharmacological action through thermalization, or an ether bond is opened and converted into a heterotype structure, so that the reduction rate of alkaloid is not high, but the reduction rate of toxicity is high, the toxicity of the nux vomica is reduced, and the effective components of the nux vomica are reserved.
The features and properties of the present application are described in further detail below with reference to examples.
Example 1
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 500g of wormwood, 250g of elderberry, 250g of garden balsam stem, 250g of suberect spatholobus stem, 250g of common clubmoss herb, 250g of beautiful sweetgum fruit, 250g of Chinese taxillus twig, 250g of nux vomica, 250g of common monkshood mother root, 250g of Indian stringbush root, 250g of pseudo-ginseng, 250g of flemingia root, 250g of ovate leaf holly bark, 500g of pepper and 500g of red cluster pepper.
The preparation method comprises the following steps: parching semen Strychni with sand at 200 deg.C for 12 min; soaking radix Aconiti in water, changing water for 2 times every day, and taking out when the radix Aconiti is slightly spicy; mixing semen Strychni parched with semen Strychni and radix Aconiti rinsed with folium Artemisiae Argyi, ramulus Sambuci Williamsii, caulis et folium Gaultheriae Yunnanensis, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, Notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with liquor, wherein the ratio of the medicinal materials to the liquor is 1: 7, soaking for 12 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at a low temperature of-25 ℃ to obtain the medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 2
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 480g of wormwood, 280g of elderberry, 280g of garden balsam stem, 280g of suberect spatholobus stem, 280g of common clubmoss herb, 280g of beautiful sweetgum fruit, 280g of Chinese taxillus twig, 280g of nux vomica, 280g of common monkshood mother root, 280g of Indian stringbush root, 280g of pseudo-ginseng, 280g of Indian buead, 280g of Illicium chinense, 350g of Chinese prickly ash and 350g of finger red pepper.
The preparation method comprises the following steps: parching semen Strychni with sand at 160 deg.C for 8 min; soaking radix Aconiti in water, changing water for 2 times every day, and taking out when the radix Aconiti is slightly spicy; mixing semen Strychni parched with semen Strychni and radix Aconiti rinsed with folium Artemisiae Argyi, ramulus Sambuci Williamsii, caulis et folium Gaultheriae Yunnanensis, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, Notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with white spirit, wherein the ratio of the medicinal materials to the white spirit is 1: 6, soaking for 10 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at the low temperature of-30 ℃ to obtain the medicinal liquor, sealing the medicinal liquor and storing the medicinal liquor in a cool place.
Example 3
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 520g of wormwood, 300g of elderberry, 300g of garden balsam stem, 260g of suberect spatholobus stem, 250g of common clubmoss herb, 250g of beautiful sweetgum fruit, 250g of Chinese taxillus twig, 250g of nux vomica, 280g of common monkshood mother root, 280g of Indian stringbush root, 280g of pseudo-ginseng, 250g of philippine flemingia root, 250g of ovateleaf holly bark, 400g of Chinese prickly ash and 400g of red cluster pepper.
The preparation method comprises the following steps: parching semen Strychni with sand at 250 deg.C for 4 min; soaking radix Aconiti in water, changing water for 2 times every day, and taking out when the radix Aconiti is slightly spicy; mixing semen Strychni parched with radix Aconiti, folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba speranskiae tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, radix Notoginseng, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with liquor, wherein the ratio of the medicinal materials to the liquor is 1: 6.5, soaking for 15 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at the low temperature of-20 ℃ to obtain the medicinal liquor, sealing the medicinal liquor, and storing in the shade.
Example 4
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 500g of wormwood, 260g of elderberry, 260g of garden balsam stem, 280g of suberect spatholobus stem, 280g of common clubmoss herb, 290g of beautiful sweetgum fruit, 180g of Chinese taxillus twig, 180g of nux vomica, 180g of common monkshood mother root, 180g of Indian stringbush root, 140g of pseudo-ginseng, 140g of philippine flemingia root, 140g of ovate leaf holly bark, 350g of Chinese prickly ash and 350g of red cluster pepper.
The preparation method comprises the following steps: parching semen Strychni with sand at 190 deg.C for 10 min; soaking radix Aconiti in water, changing water for 2 times every day, and taking out when the radix Aconiti is slightly spicy; mixing semen Strychni parched with radix Aconiti, folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba speranskiae tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, radix Notoginseng, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
and mixing the dried raw medicinal materials with liquor, wherein the ratio of the medicinal materials to the liquor is 1: 7.5, mixing, soaking for 13 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at the low temperature of-23 ℃ to obtain the medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 5
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 520g of wormwood, 300g of elderberry, 300g of garden balsam stem, 300g of suberect spatholobus stem, 300g of common clubmoss herb, 250g of beautiful sweetgum fruit, 250g of Chinese taxillus twig, 250g of nux vomica, 250g of common monkshood mother root, 250g of Indian stringbush root, 250g of pseudo-ginseng, 250g of flemingia root, 250g of ovateleaf holly bark, 450g of Chinese prickly ash and 450g of red cluster pepper.
The preparation method comprises the following steps: parching semen Strychni with sand at 160 deg.C for 12 min; soaking radix Aconiti in water, changing water for 2 times every day, and taking out when the radix Aconiti is slightly spicy; mixing semen Strychni parched with radix Aconiti, folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba speranskiae tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, radix Notoginseng, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with liquor, wherein the ratio of the medicinal materials to the liquor is 1: 8, soaking for 15 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at the low temperature of-26 ℃ to obtain the medicinal liquor, sealing the medicinal liquor, and storing in a shade place.
Example 6
A traditional Chinese medicine medicated wine for treating arthralgia comprises white spirit and the following raw materials in parts by weight: 500g of wormwood, 260g of elderberry, 260g of garden balsam stem, 250g of suberect spatholobus stem, 250g of common clubmoss herb, 200g of beautiful sweetgum fruit, 200g of Chinese taxillus twig, 200g of nux vomica, 200g of common monkshood mother root, 200g of Indian stringbush root, 200g of pseudo-ginseng, 200g of flemingia root and 200g of ovate leaf holly bark.
The preparation method comprises the following steps: parching semen Strychni with sand at 170 deg.C for 6 min; soaking radix Aconiti in water, changing water for 2 times every day, and taking out when the radix Aconiti is slightly spicy; mixing semen Strychni parched with radix Aconiti, folium Artemisiae Argyi, ramulus Sambuci Williamsii, herba speranskiae tuberculatae, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, radix Notoginseng, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and fructus Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with liquor, wherein the ratio of the medicinal materials to the liquor is 1: 7, soaking for 10 days, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution at the low temperature of-24 ℃ to obtain the medicinal liquor, sealing the medicinal liquor and storing the medicinal liquor in a cool place.
Comparative example
This comparative example is essentially the same as example 1 except that no wormwood was added.
Examples of effects
22 patients with hyperosteogeny, 24 patients with lumbar intervertebral disc protrusion (bulging and slipping), 20 patients with lumbar spinal stenosis, 19 patients with ankylosing spondylitis, 27 patients with cervical spondylosis (bulging, bulging and slipping), 21 patients with rheumatic arthritis and gall, 18 patients with rheumatoid arthritis pain, 15 patients with sciatica and 15 patients with lumbar muscle strain are selected.
The patients were randomized into 7 groups with no significant difference in each group.
The using method comprises the following steps:
the medicinal liquor is applied to the affected part or the part with pain, and is applied once in the morning, the middle and the evening each day, the patient with severe disease can be applied 5-6 times a day, the applied part is cleaned or disinfected by iodine solution before application, 7 days is a treatment course, three continuous treatment courses are optimal, and the medicinal effect is counted after one treatment course.
Note that: a. it is forbidden for patients with alcohol allergy; b. is forbidden for pregnant women; c. it is contraindicated in menstrual period; d. the traumatic injury is not forbidden for more than 24 h; e. if the precipitate exists, the use effect is not influenced.
The evaluation standard of curative effect is as follows:
and (3) curing: the pain symptom disappears, the shoulder and neck ache sign disappears, the detection index accords with the regulation, and the function returns to normal;
the effect is shown: the pain symptom disappears, the shoulder and neck ache sign is obviously relieved, the detection index is qualified, and the normal life is not influenced;
the method has the following advantages: relief of symptoms, which have an impact on life;
and (4) invalidation: the symptoms are not improved and are even more aggravated, and other medicaments are needed to be selected for treatment.
Specific statistics are shown in table 1.
TABLE 1
The effective rate is (effective number of people + cured number of people)/total number of people;
the cure rate is the number of cured people/the total number of people;
as can be seen from table 1, the effective rates of examples 1 to 6 and the comparative example are 100%, and the cure rate of example 1 is 93%, which indicates that the medicated wine prepared by example 1 has the best effect; in the comparative example, the cure rate is 81% without adding the wormwood, and the wormwood is a main drug in the traditional Chinese medicine composition and plays an important role in the traditional Chinese medicine composition; in example 6, zanthoxylum bungeanum and zanthoxylum piperitum are not added, the cure rate is 88%, and the zanthoxylum bungeanum and zanthoxylum piperitum are mutually matched, so that the effects of strengthening and stimulating the surface skin, expanding pores and promoting the quick absorption of liquid medicine are achieved.
Typical case 1: in Zhou-chi, male, 51 years old, with lumbar disc herniation for 5 years, frequent lumbar pain, no sedentary or long standing, pain can be caused by forced pain caused by taking analgesic; the effect is not good after the patient goes to a hospital for treatment, pain frequently and repeatedly attacks, and then physical therapy is carried out, and the effect of relieving the pain is not obvious. After the medicinal liquor is externally applied for 2 days, the lumbar pain is obviously improved, after the medicinal liquor is continuously used for 1 treatment course, the pain symptom completely disappears, and the medicinal liquor is continuously used for a long time without relapse.
Typical case 2: a certain king, a woman in age of 32 years, working at a desk for a long time, lumbar vertebra strain is severe and is accompanied by scapulohumeral periarthritis and cervical vertebra hyperplasia, various methods are tried for treatment, for example, the effects of taking anti-inflammatory analgesic drugs, massaging, acupuncture and moxibustion and the like are poor, the patient cannot bend down at ordinary times, the waist is sour and swollen during sleeping, the patient cannot fall asleep, normal life and work are affected, the lumbar vertebra pain is obviously improved after the medicinal liquor is externally applied for 3 days, and after the medicinal liquor is continuously used for 1 treatment course, pain symptoms completely disappear, and the patient can normally work and live.
In summary, according to the traditional Chinese medicine wine for treating arthralgia and the preparation method thereof provided by the embodiment of the application, in the traditional Chinese medicine composition, the wormwood is used for dredging twelve meridians and running three yin, has the effects of dispelling wind and removing dampness, clearing and activating the channels and collaterals, and reducing swelling and dissipating stagnation, is pure yang in nature, can penetrate all the meridians to remove various diseases due to moxibustion fire, and is a monarch drug; the elderberry, the garden balsam stem, the suberect spatholobus stem and the common clubmoss herb are mutually matched, can expel wind and remove dampness, relax muscles and tendons, promote blood circulation, relieve swelling and stop pain, is a ministerial drug, and can be used for joint ache and difficulty in flexion and extension by matching with a monarch drug; fructus Lipuidambaris, herba Taxilli, semen Strychni, radix Aconiti and Indian Stringbush are adjuvant drugs, wherein fructus Lipuidambaris and Indian Stringbush cooperate with each other to clear heat and toxic substances, induce diuresis and dredge channels; the nux vomica and the radix aconiti are mutually matched, so that the effects of dredging collaterals, relieving pain, dissipating stagnation and reducing swelling can be achieved; herba Taxilli has effects of nourishing liver and kidney, and strengthening tendons and bones; can be used in combination with principal drugs for treating rheumatic arthralgia, soreness of waist and knees, and weakness of tendons and bones; pseudo-ginseng, Qianjin and Ilicis rotunda are guiding drugs, wherein the pseudo-ginseng and Ilicis rotunda have the effects of clearing heat, promoting diuresis, relieving swelling and pain, and the Ilicis rotunda can dispel wind-damp, supplement qi and blood, strengthen waist and knees; the combination of the medicines can dredge the channels and activate blood circulation, so that the medicinal components in the medicinal materials pass through the twelve channels and travel throughout the whole body, and the medicinal liquor with super-strong permeability can quickly permeate to the pain part of a patient to directly reach the focus. The medicinal liquor has the advantages of having super strong permeability, being capable of rapidly permeating to the pain affected part of a patient, drawing out poison and dissipating blood stasis, diminishing inflammation and sterilizing, dispelling wind and removing dampness, strengthening tendons and bones, relieving swelling and pain, and repairing damaged tissues and cells, thereby achieving the rehabilitation in the true sense. The Chinese medicinal composition has reasonable compatibility, and can be used for treating various diseases such as arthralgia, soreness of waist and knees, myasthenia of bones and muscles, rheumatic arthritis, lumbago and skelalgia, and lumbar muscle strain.
The embodiments described above are some, but not all embodiments of the present application. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
Claims (10)
1. The traditional Chinese medicine liquor for treating arthralgia is characterized by comprising white spirit and the following raw materials in parts by weight: 450-550 parts of wormwood, 230-400 parts of elderberry, 230-400 parts of garden balsam stem, 230-400 parts of suberect spatholobus stem, 230-400 parts of common clubmoss herb, 120-300 parts of beautiful sweetgum fruit, 120-300 parts of Chinese taxillus twig, 120-300 parts of nux vomica, 120-300 parts of common monkshood mother root, 120-280 parts of Indian stringbush root, 80-250 parts of pseudo-ginseng, 80-250 parts of jack-in-the-palm and 80-250 parts of ovateleaf holly bark.
2. The traditional Chinese medicine wine for treating arthralgia according to claim 1, which is characterized by further comprising 300-600 parts of pepper and 300-600 parts of zanthoxylum piperitum.
3. The traditional Chinese medicine liquor for treating arthralgia according to claim 2, which is characterized by comprising white spirit and the following raw materials in parts by weight: 480-520 parts of wormwood, 250-300 parts of elderberry, 250-300 parts of garden balsam stem, 250-300 parts of suberect spatholobus stem, 250-300 parts of common clubmoss herb, 180-250 parts of beautiful sweetgum fruit, 180-250 parts of Chinese taxillus twig, 180-250 parts of nux vomica, 180-250 parts of common monkshood mother root, 180-250 parts of Indian stringbush root, 140-250 parts of pseudo-ginseng, 140-250 parts of jack-in-the-mouth, 140-250 parts of ovate holly bark, 350-550 parts of pepper and 350-550 parts of red cluster pepper.
4. The traditional Chinese medicine liquor for treating arthralgia according to claim 3 is characterized by comprising white spirit and the following raw materials in parts by weight: 500 parts of wormwood, 250 parts of elderberry, 250 parts of garden balsam stem, 250 parts of suberect spatholobus stem, 250 parts of common clubmoss herb, 250 parts of beautiful sweetgum fruit, 250 parts of Chinese taxillus twig, 250 parts of nux vomica, 250 parts of common monkshood mother root, 250 parts of Indian stringbush root, 250 parts of pseudo-ginseng, 250 parts of philippine flemingia root, 250 parts of ovate leaf holly bark, 500 parts of Chinese prickly ash and 500 parts of red cluster pepper.
5. The traditional Chinese medicine liquor for treating arthralgia according to claim 4, wherein the mass ratio of the white spirit to the raw materials is 1: 6-8.
6. The traditional Chinese medicine liquor for treating arthralgia according to any one of claims 1 to 5, wherein the degree of the white spirit is 45-60 degrees.
7. The preparation method of the traditional Chinese medicine liquor for treating arthralgia according to any one of claims 1 to 6, which is characterized by comprising the following steps:
parching semen Strychni with sand; soaking radix Aconiti in water, rinsing until the mouth tastes spicy, taking out, mixing semen Strychni parched with sand and rinsed radix Aconiti with folium Artemisiae Argyi, ramulus Sambuci Williamsii, caulis et folium Gaultheriae Yunnanensis, caulis Spatholobi, herba Lycopodii, fructus Lipuidambaris, herba Taxilli, semen Strychni, Indian Stringbush, Notoginseng radix, radix Flemingiae Philippinensis, cortex Ilicis Rotundae, fructus Zanthoxyli and radix Zanthoxyli, pulverizing, and drying;
mixing the dried raw medicinal materials with the white spirit, soaking, filtering to remove impurities, distilling the filtered liquid medicine to obtain an extracting solution, extracting the extracting solution, sealing and storing to obtain the medicinal liquor.
8. The preparation method of the traditional Chinese medicine liquor for treating arthralgia according to claim 7, wherein the soaking time is 10-15 days.
9. The preparation method of the traditional Chinese medicine wine for treating arthralgia according to claim 7, wherein the extraction temperature is-30 to-20 ℃.
10. The preparation method of the traditional Chinese medicine wine for treating arthralgia according to claim 7, wherein the sand-frying temperature is 160-250 ℃, and the sand-frying time is 4-15 min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210417026.0A CN115006473B (en) | 2022-04-20 | 2022-04-20 | Traditional Chinese medicine wine for treating arthralgia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210417026.0A CN115006473B (en) | 2022-04-20 | 2022-04-20 | Traditional Chinese medicine wine for treating arthralgia and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115006473A true CN115006473A (en) | 2022-09-06 |
| CN115006473B CN115006473B (en) | 2023-11-07 |
Family
ID=83066465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210417026.0A Active CN115006473B (en) | 2022-04-20 | 2022-04-20 | Traditional Chinese medicine wine for treating arthralgia and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115006473B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258209A (en) * | 2014-09-25 | 2015-01-07 | 苏州市天灵中药饮片有限公司 | External medicinal liquor for treating gout and preparation method thereof |
| CN104644943A (en) * | 2015-01-27 | 2015-05-27 | 王廷见 | Traditional Chinese medicine composition, medicinal moxibustion containing same and preparation method |
| CN109498699A (en) * | 2018-12-28 | 2019-03-22 | 宋永盛 | A kind of liquid medicine and preparation method thereof for treating rheumatic and rheumatoid |
-
2022
- 2022-04-20 CN CN202210417026.0A patent/CN115006473B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258209A (en) * | 2014-09-25 | 2015-01-07 | 苏州市天灵中药饮片有限公司 | External medicinal liquor for treating gout and preparation method thereof |
| CN104644943A (en) * | 2015-01-27 | 2015-05-27 | 王廷见 | Traditional Chinese medicine composition, medicinal moxibustion containing same and preparation method |
| CN109498699A (en) * | 2018-12-28 | 2019-03-22 | 宋永盛 | A kind of liquid medicine and preparation method thereof for treating rheumatic and rheumatoid |
Non-Patent Citations (2)
| Title |
|---|
| 国凯;潘廷军;: "自制祛风活血定痛酊经离子导入临床应用初探", no. 01, pages 136 - 137 * |
| 龚应平;: "中药治疗膝骨性关节炎的研究", no. 02, pages 40 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115006473B (en) | 2023-11-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103393916B (en) | External use ointment used for treating dermatitis and preparation method thereof | |
| CN108619478A (en) | A kind of Chinese medicine preparation for treating treating rheumatic ostealgia | |
| CN107184782A (en) | External medicine composition, preparation method and applications | |
| CN101181444B (en) | Multi-efficacy externally used drug as well as method for preparing immersion agent thereof | |
| CN102626505A (en) | Massaging paste based on Chinese medicinal herbs and preparation method thereof | |
| CN107095905A (en) | A kind of healthful moxibustion bar and moxibustion cream | |
| CN103705791B (en) | Medicament for clinical anesthesia and preparation method thereof | |
| CN108379385A (en) | A kind of Chinese medicine preparation and preparation method thereof for treating neck-shoulder pain, lumbago and leg pain | |
| CN115006473B (en) | Traditional Chinese medicine wine for treating arthralgia and preparation method thereof | |
| CN103191330A (en) | Traditional Chinese medicine used for treating swelling of limbs of hemiplegic patient | |
| CN105561270A (en) | Analgesic Chinese herbal medicine for external application and preparation method thereof | |
| CN105770847A (en) | Traditional Chinese medicine composition for relieving or treating joint swelling and pain and preparation method and application of traditional Chinese medicine composition | |
| CN111603528A (en) | A topical medicine for treating pain and regulating channels and collaterals, and its preparation method | |
| CN105998840A (en) | External use ointment used for treating insect bite dermatitis and preparation method | |
| CN104887970A (en) | Acupuncture and moxibustion physiotherapy ointment for external use | |
| CN110038101A (en) | A kind of Chinese medicine is dispelled antipruritic external preparation of pain and preparation method thereof | |
| CN116392524B (en) | Traditional Chinese medicine composition for treating hyperostosis and rheumatic arthritis and application thereof | |
| CN108186864A (en) | A kind of Chinese medicine for treating acne | |
| CN115192689B (en) | Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, application and traditional Chinese medicine preparation thereof | |
| CN116098976B (en) | Medicinal liquor for relaxing muscles, activating blood circulation, detumescence and relieving pain | |
| CN102949544A (en) | Chinese medicinal composition for specifically treating swelling of hands and feet of hemiplegic patients | |
| CN105617273A (en) | Pharmaceutic preparation for promoting wound healing and application thereof | |
| CN107617071A (en) | A kind of capsule and preparation method for being used to treat bone tuberculosis | |
| CN105535853A (en) | Traditional Chinese medicine composition for treating bedsores for clinical nursing | |
| CN104888147A (en) | Traditional Chinese medicine ointment for shoulder periarthritis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20231128 Address after: East Floor 1, Building C4, Biological Innovation Park, No. 666, Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province 430000 Patentee after: Hubei Chang'e Biological Co.,Ltd. Address before: No. 92, Danshui Baiyun 2nd Road, Huiyang District, Huizhou City, Guangdong Province, 516200 Patentee before: Guangdong Huibo Pharmaceutical Technology Co.,Ltd. |
|
| TR01 | Transfer of patent right |