CN101181444B - Multi-efficacy externally used drug as well as method for preparing immersion agent thereof - Google Patents

Multi-efficacy externally used drug as well as method for preparing immersion agent thereof Download PDF

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CN101181444B
CN101181444B CN200710031494XA CN200710031494A CN101181444B CN 101181444 B CN101181444 B CN 101181444B CN 200710031494X A CN200710031494X A CN 200710031494XA CN 200710031494 A CN200710031494 A CN 200710031494A CN 101181444 B CN101181444 B CN 101181444B
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gram
radix aconiti
efficacy
rhizoma
externally used
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CN101181444A (en
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刘海燕
卿余庆
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Abstract

The invention relates to a multi-functional externally used drug and the production method of soaking agent. The invention crushes the compound of Chinese herbs of seven Chinese traditional medicines of semen capparis, sedum uizoon, raw radix aconite, raw wild aconite, rhizoma arisaematis, raw tuber pinellia and Paris polyphylla as certain shares and dips for 3 to 5 months through white vinegar, concentrated to form the drug. The invention has the advantages that first, sore anthema and particular itch are cured for once or twice, the functions for cleaning hair, removing scall and relieving itching excels to varied shampoo; secondly, hemorrhoids gall disappears for 5 minutes; thirdly, nodule, boil and pyogenic infections are cured for one dab; fourthly, acne and nail ringworm are eliminated for 10 days and the functions are not assimilated by acne calming and nail brighting; fifthly, effects on galls from falls quickly appear; and the invention is effective for osteoarthritis, osteoporosis, rheumatoid arthritis, neuropathic pain and thrombophlebitis.

Description

The preparation method of multi-efficacy externally used drug and soaking agent thereof
Technical field
The present invention relates to a kind of medicine for external use, particularly a kind of to treatment swelling and pain of hemorrhoid, tinea unguium, tuberculosis, sore swollen toxin, acne, the medicine for external use that the skin ulcer rash is very itched and treating swelling and pain by traumatic injury, osteoarthritis, osteoporosis, rheumatoid arthritis, neuropathic pain, thrombophlebitis are effectual and the preparation method of soaking agent thereof.
Background technology
The formation of surgical diseases is blocked nothing more than coagulation of QI-blood, disharmony of nutrient QI with defensive QI, meridians and evil heap soil or fertilizer over and around the roots of poison held back.The way of treatment is nothing but treatment by oral administration of medicines and external treatment.Treatment by oral administration of medicines divides in principle and disappears, holds in the palm, mends three kinds of methods.External treatment is various, as: plaster applying a plaster for therapeutic purpose, enclose medicine, dusting powder drug, wash, acupuncture, operate on etc.Poison is cured the disease, and sees " interior warp " the earliest, and the branch of very toxic, drug with little toxicity, mild toxicity, so-called " big poison is cured the disease, ten go its six; Drug with little toxicity is cured the disease, ten go its seven or eight; Mild toxicity is cured the disease, ten go its eight or nine ".
A kind of antiinflammatory detumescent pain-stopping external use medicine is disclosed among the Chinese patent literature CN1404850A, it is with Radix Arnebiae (Radix Lithospermi), Bulbus Fritillariae Cirrhosae, Semen Strychni, Flos Carthami, Radix Cyathulae, Rhizoma Corydalis, Sanguis Draxonis, Caulis Clematidis Armandii, catechu, Radix Aconiti, Pseudobulbus cremastrae seu pleiones, the Rhizoma Pinelliae, Radix Aconiti Kusnezoffii, Herba Taraxaci, Radix Angelicae Sinensis, Lignum Sappan, Rhizoma Arisaematis, Caulis Mahoniae, Fructus Piperis Longi, Caulis Spatholobi is the external-use drug form that raw material is made, be mainly used in treatment because of tumor, whole body that cancer etc. cause or local edema, especially to the difficult patient with advanced cancer of taking medicine, the unique curative effect that more can show its inner disease outer treat, it can eliminate patient's edema in a short time, and its effective percentage reaches more than 96%.Said herbal medicine all has its unique therapeutic efficiency, but mixes the support that the effect of using the back does not have clinical use data.
Summary of the invention
Purpose of the present invention aims to provide a kind of to treatment swelling and pain of hemorrhoid, tinea unguium, tuberculosis, sore swollen toxin, acne, the multi-efficacy externally used drug that the skin ulcer rash is very itched and treating swelling and pain by traumatic injury, osteoarthritis, osteoporosis, rheumatoid arthritis, neuropathic pain, thrombophlebitis are effectual and the preparation method of soaking agent thereof, to overcome the deficiencies in the prior art.
A kind of multi-efficacy externally used drug by this purpose design is characterized in that its key component and weight portion are:
Semen Capparis 10-20 Herba Senecionis Chrysanthemoidis 10-20
Radix Aconiti 12-20 Radix Aconiti Kusnezoffii 12-20
Rhizoma Arisaematis 12-20 Rhizoma Pinelliae 12-20
Rhizoma Paridis 12-20.
Its optimization component and weight portion are:
Semen Capparis 10-12 Herba Senecionis Chrysanthemoidis 10-12
Radix Aconiti 15-18 Radix Aconiti Kusnezoffii 15-18
Rhizoma Arisaematis 15-18 Rhizoma Pinelliae 15-18
Rhizoma Paridis 15-18.
A kind of preparation method of multi-efficacy externally used drug soaking agent, after it is characterized in that choosing Semen Capparis 10-20 gram, Herba Senecionis Chrysanthemoidis 10-20 gram, Radix Aconiti 12-20 gram, Radix Aconiti Kusnezoffii 12-20 gram, Rhizoma Arisaematis 12-20 gram, Rhizoma Pinelliae 12-20 gram and Rhizoma Paridis 12-20 gram and smashing mixing, add 800-1000 gram white vinegar again and soak the 3-5 month, make its acid-base neutralization, concentrate to get the external soaking agent.
Above-mentioned external soaking agent can be brewed into externally-applied ointment with addition of attached oil preparation.
Advantage of the present invention is as follows: 1, the skin ulcer rash very itch 1 twice more, the hair washing removing scurf and relieving itching is better than various shampoos; 2, swelling and pain of hemorrhoid disappeared in five minutes; 3, tuberculosis, sore swollen toxin one rub and take effect; 4, acne, tinea unguium can be gone in ten days, and Benzoyl Peroxide, bright first are incomparable; 5, the treating swelling and pain by traumatic injury produce effects is faster, and osteoarthritis, osteoporosis, rheumatoid arthritis, neuropathic pain, thrombophlebitis all can be imitated.
The specific embodiment
Below in conjunction with drawings and Examples the present invention is further described.
This multi-efficacy externally used drug is formed by component and the weight portion system of mixing by Semen Capparis, Herba Senecionis Chrysanthemoidis, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae and seven kinds of Chinese herbal medicine of Rhizoma Paridis.
Usual amounts multi-efficacy externally used drug soaking agent, after choosing Semen Capparis 10-20 gram, Herba Senecionis Chrysanthemoidis 10-20 gram, Radix Aconiti 12-20 gram, Radix Aconiti Kusnezoffii 12-20 gram, Rhizoma Arisaematis 12-20 gram, Rhizoma Pinelliae 12-20 gram and Rhizoma Paridis 12-20 gram and smashing mixing, add 800-1000 gram white vinegar again and soak the 3-5 month, make its acid-base neutralization, concentrate to get the external soaking agent.
Optimized amount multi-efficacy externally used drug soaking agent, after choosing Semen Capparis 10-12 gram, Herba Senecionis Chrysanthemoidis 10-12 gram, Radix Aconiti 15-18 gram, Radix Aconiti Kusnezoffii 15-18 gram, Rhizoma Arisaematis 15-18 gram, Rhizoma Pinelliae 15-18 gram and Rhizoma Paridis 15-18 gram and smashing mixing, add 800-1000 gram white vinegar again and soak the 3-5 month, make its acid-base neutralization, concentrate to get optimized amount external soaking agent.
The characteristic of said herbal medicine is as follows:
1, Semen Capparis
Nature and flavor: cold in nature, bitter in the mouth; Nontoxic.
Function cures mainly summary: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, removing heat from blood YIN nourishing.Clinical practice: hemorrhoid, furuncle, acne, hypertension.
2, Herba Senecionis Chrysanthemoidis
Meridian distribution of property and flavor: cold in nature, sweet and slightly bitter taste.Return liver, kidney channel.
Function cures mainly summary: dissipating blood stasis hemostasis, subduing swelling and relieving pain.Hemoptysis, spit blood, have blood in stool, epistaxis, metrorrhagia, traumatic hemorrhage, the breast ventral spine is hindered, treating swelling and pain by traumatic injury, diseases such as carbuncle furuncle, for oral administration outer rub all effective.
3, Radix Aconiti
Composition: contain multiple alkaloid.As follows Aconitum carmichjaelii Debx., aconitine, mesaconitine etc.
Pharmacology: reinforcement, blood vessel dilating, antiinflammatory drawn game anaesthetic effect.Aconitum carmichjaelii Debx., Radix Aconiti Lateralis Preparata and aconitine can stimulate the sensory nerve ending of local skin, mucosa, excitement earlier to produce pruritus and burning sensation, continue with anesthesia, lose one's senses.
Meridian distribution of property and flavor: hot in nature, acrid in the mouth is poisonous.GUIXIN, liver, spleen channel.
Function cures mainly summary: wind-damp dispelling, dispersing cold for relieving pain.Be used for the treatment of the limb fiber crops, wind syndrome of head pain, migraine, carbuncle of yin nature, diseases such as traumatic injury pain.
4, Radix Aconiti Kusnezoffii
Composition: the Aconitum carmichjaelii Debx. part all contains alkaloid, wherein is mainly aconitine.Generate black former alkali etc. after the Aconitum carmichjaelii Debx. hydrolysis.
Pharmacology: analgesia; Mucomembranous anesthesia, clinical observation has the local anesthesia effect to mucosa, but can not be deep into the deep of mucosa; Decreased heart rate; Blood vessel dilating.
Meridian distribution of property and flavor: hot in nature, acrid in the mouth is poisonous.Return lung, liver, spleen channel.
Function cures mainly summary: wind-damp dispelling, dispersing cold for relieving pain.Be used for arthralgia due to cold-dampnes, trusted subordinate's cold type of pain, wind syndrome of head pain, migraine, diseases such as traumatic injury pain.The Radix Aconiti Kusnezoffii Radix Aconiti all claims Aconitum carmichjaelii Debx..Right Radix Aconiti Kusnezoffii all parts of the country all produce, and are wild; Radix Aconiti main product Sichuan, artificial carrying trained.The two all has a wind-damp dispelling, the merit of dispersing cold for relieving pain, but each tool speciality.The right violent gas of Radix Aconiti Kusnezoffii property is sharp, and toxicity is very big, searches wind prevailing over dampness, changes persistent ailment, controls malignant boil, the meridian dredging, and sharp joint, through sick institute, power wins Radix Aconiti.Radix Aconiti property is dispeled the wind suddenly, and toxicity can be pursued wind-cold damp pathogen a little less than than Radix Aconiti Kusnezoffii being, is longer than the cold pain of dispeling the wind.Radix Aconiti, the same usefulness of Radix Aconiti Kusnezoffii, then expelling wind and cold is strong by wind pain relieving ability.
Clinical practice: tetanus.Lymphadenitis, lymphoid tuberculosis.In itch.Alopecia areata.The tinea manuum, tinea unguium.General actute infection of surgery and closed trauma disease such as swell and ache.Facial paralysis.
5, Rhizoma Arisaematis
Composition: tuber contains poisonous alkaloid, severe peppery property toxin, triterpenoid saponin and the acid etc. of resting in peace.Fruit and seed still contain the material of similar toxin.
Pharmacology: anticonvulsant action.Calm, analgesic activity.Phlegm-dispelling functions.The aqueous extract of bright Rhizoma Arisaematis has the obvious suppression effect through pure post precipitation concentrating agents to the Hela cell.Make cell concentration become agglomerate, lost normal cellularity, part cell and obscission has taken place.The experimental tumor that mice is carried out comprises sarcoma S 180, HCA (hepatocarcinoma) solid type, and the squamous epithelial cancer uterus carcinoma all has obvious antitumaous effect.
Meridian distribution of property and flavor: warm in nature, bitter in the mouth is hot, and is poisonous.Return lung, liver, spleen channel.
Function cures mainly summary: dry damp-phlegm eliminating, wind-expelling pain-stopping.Wind-phlegm gushes and by diseases such as the limb paralysis due to the wind-phlegm, dizzy, infantile convulsion locked mouth in the extensively treating.External can be controlled carbuncle sore tumefacting virus, sucutaneous nodule cancerous protuberance, diseases such as wound congestive edema.Popular rib adenitis.Cervical cancer.Infantile thrush, erosion of the oral mucosa.The inclined to one side cellulitis of brain.Hordeolum.Scrofula from the beginning of.
6, Rhizoma Pinelliae
Composition: contain volatile oil, L-ephedrine, several amino acids etc.
Pharmacology: relieving cough and expelling phlegm.Tell and emetic action in the town.Antitumaous effect.The Rhizoma Pinelliae all has the obvious suppression effect to experimental tumor and He1a cell.Animal hepatocarcinoma also there is the obvious suppression effect.Detoxication.The derivative of glucuronic acid that the Rhizoma Pinelliae contains has tangible Detoxication.Effect weakens to animal toxicity can to make native peaceful acetic acid choline.
Meridian distribution of property and flavor: warm in nature, acrid in the mouth is poisonous.Return spleen, stomach, lung meridian.
Function cures mainly summary: dry damp-phlegm eliminating, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.But Rhizoma Pinelliae external eliminating carbuncle sore swollen toxin.Clinical practice: acute mastitis.The acute-chronic purulent otitis media.Dentinal cartilage film inflammation.Dry socket.Alopecia etc.
7, Rhizoma Paridis
Composition: the Rhizoma Paridis rhizome mainly contains and stays the body Saponin, promptly paridin, eat multiple Saponins such as Chinese yam Saponin.
Pharmacology: relieving asthma, antitussive action.Antibacterial action, flea body water decoction is to multiple dysentery bacterium and typhoid fever, Salmonella paratyphi, large intestine, paracolon, staphylococcus aureus, Hemolytic streptococcus, meningococcus all have antibacterial action, and wherein the inhibition ability to pyococcus is excellent than Rhizoma Coptidis.
Meridian distribution of property and flavor: cold nature, bitter in the mouth, slightly poisonous.Return Liver Channel.
Function cures mainly summary: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, dispelling wind and relieving convulsion.This product has the effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, is usually used in the carbuncle furuncle, venom, diseases such as traumatic pain.Effect with dispelling wind and relieving convulsion is applicable to diseases such as infantile convulsion tic and epilepsy.Clinical practice is in psoriasis, itching skin disease, external genitalia ulcer, male mammary gland lump, folliculitis etc.
Below be that medicine for external use to above-mentioned preparation carries out the data (2003) that write down after the clinical use:
The Municipal Disease Control and Prevention Center, zhuzhou, hunan province once used said herbal medicine that 16 tinea unguium patients are treated, all recovery from illness.Wherein, two people in 3~5 years of the course of disease, healing time 20~30 days; Seven people in 5~10 years of the course of disease, healing time 25~50 days; Two people in 10~15 years of the course of disease, healing time 35~55 days; Five people of the course of disease more than 15 years, healing time 60~90 days.
62 years old male patients
Symptom and sign: mucosal erosion on the pectinate line, blood stasis is deviate from incarceration during defecation, many, the pain of the amount of having blood in stool.
Diagnosis: be diagnosed as " internal hemorrhoid III " through Hunan Province Longhui Chinese Medicine Hospital.
Therapeutic outcome: under the situation of not performing an operation, use above-mentioned multi-efficacy externally used drug to cure.
67 years old male patients
Symptom and sign: 98 year autumn found that left breast ovum circle lump matter was hard, and clear border and surrounding tissue do not have adhesion, do not have tangible pain.Reaching the Ovum Anas domestica great talent in 2003 goes to a doctor.
Diagnosis: through Longhui County, Hunan Province hospital diagnosis is " cyclomastopathy ".
Therapeutic outcome: use above-mentioned multi-efficacy externally used drug treatment under the situation of not performing an operation, be coated with the first quarter moon that rubs, no unpleasantness disappears.
20 years old male patients
Symptom and sign: face covers with a meter shot-like particle, and to crossfade into Semen phaseoli radiati big, is taupe, one year, and with multiple controlling " acne " medicine is invalid excessively.
Diagnosis: through the Beijing Military Area Command of PLA hospital diagnosis is " verruca plana comedo ".
Therapeutic outcome: use above-mentioned multi-efficacy externally used drug to be coated with for 50 milliliters and rub seven days more.
40 years old male patients
Symptom and sign: myxedema on the pectinate line, blood stasis is deviate from during defecation, and available hands resets, and has blood in stool.
Diagnosis: be diagnosed as " internal hemorrhoid " through Hunan Province Longhui Chinese Medicine Hospital.
Therapeutic outcome: under the situation of not performing an operation, use above-mentioned multi-efficacy externally used drug to cure.
55 years old male patients
Symptom and sign: anus edge edema is routed up, big livid purple thrombosis one circle of Semen Maydis grain.Pain recoil uneasiness.
Diagnosis: refined hospital diagnosis is " a varicosis type thrombosed external hemorrhoid " through Hunan, Hunan Province.
Therapeutic outcome: have only and use above-mentioned multi-efficacy externally used drug to cure.
38 years old female patients
Symptom and sign: whole body pain, spasm of the limbs syncope, six kinds of pulses are not existing, whole body is ice-cold.
Diagnosis: be diagnosed as through commune hospital, transverse slat bridge center, Hunan Province by " cerebral thrombosis blood vessel stasis of blood plug ".
Therapeutic outcome: use 100 milliliters of above-mentioned multi-efficacy externally used drugs, the two people hands that rubs, the two people foot that rubs, five minutes transference cures are accused more.
35 years old female patients
Symptom and sign: the RG heat that swells and ache has an intense pain hyperpyrexia shiver with cold, coma, groin.
Diagnosis: the commune hospital is diagnosed as " cellulitis " through transverse slat bridge center, Hunan Province.
Therapeutic outcome: use above-mentioned multi-efficacy externally used drug to be coated with and rub five days more.

Claims (4)

1. multi-efficacy externally used drug is characterized in that its key component and weight portion are:
Semen Capparis 10-20 Herba Senecionis Chrysanthemoidis 10-20
Radix Aconiti 12-20 Radix Aconiti Kusnezoffii 12-20
Rhizoma Arisaematis 12-20 Rhizoma Pinelliae 12-20
Rhizoma Paridis 12-20.
2. multi-efficacy externally used drug according to claim 1 is characterized in that its optimization component and weight portion are:
Semen Capparis 10-12 Herba Senecionis Chrysanthemoidis 10-12
Radix Aconiti 15-18 Radix Aconiti Kusnezoffii 15-18
Rhizoma Arisaematis 15-18 Rhizoma Pinelliae 15-18
Rhizoma Paridis 15-18.
3. the preparation method of a multi-efficacy externally used drug soaking agent, after it is characterized in that choosing Semen Capparis 10-20 gram, Herba Senecionis Chrysanthemoidis 10-20 gram, Radix Aconiti 12-20 gram, Radix Aconiti Kusnezoffii 12-20 gram, Rhizoma Arisaematis 12-20 gram, Rhizoma Pinelliae 12-20 gram and Rhizoma Paridis 12-20 gram and smashing mixing, add 800-1000 gram white vinegar again and soak the 3-5 month, make its acid-base neutralization, concentrate to get the external soaking agent.
4. the externally-applied ointment of making according to the preparation method of the described multi-efficacy externally used drug soaking agent of claim 3 is characterized in that the external soaking agent can be brewed into externally-applied ointment with addition of attached oil preparation.
CN200710031494XA 2007-11-16 2007-11-16 Multi-efficacy externally used drug as well as method for preparing immersion agent thereof Expired - Fee Related CN101181444B (en)

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102824513A (en) * 2012-09-14 2012-12-19 贺新辉 External liniment and preparation method thereof
CN103690845B (en) * 2013-12-09 2016-06-29 朱育盼 A kind of Chinese medicine treating marrow angiopathy
CN103919954A (en) * 2014-05-03 2014-07-16 赵东顺 External-application powder for treating evil carbuncle, deep-rooted ulcer and sores
CN104383216A (en) * 2014-10-28 2015-03-04 王盛兴 Medicine for treating decayed tooth and anemogenous toothache and preparation method of medicine
CN107617053A (en) * 2017-10-29 2018-01-23 贵州松桃信仁苗药有限公司 A kind of composition for treating hemorrhoid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴大真等.中药治疗癌症疼痛的临床应用概况.中国中医基础医学杂志4 4.1998,4(4),61-64. *

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