CN114984122A - 一种用于治疗急慢性鼻炎的中药膏 - Google Patents

一种用于治疗急慢性鼻炎的中药膏 Download PDF

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CN114984122A
CN114984122A CN202210596709.7A CN202210596709A CN114984122A CN 114984122 A CN114984122 A CN 114984122A CN 202210596709 A CN202210596709 A CN 202210596709A CN 114984122 A CN114984122 A CN 114984122A
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袁庆堂
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Abstract

本发明提供了一种用于治疗急慢性鼻炎的中药膏，包括以下重量份的组分：鹅不食草5‑10份，苍耳子2‑8份，辛夷2‑8份，甜瓜蒂1‑3份，冰片1‑5份，麻黄1‑3份，紫苏叶0.5‑1.5份，荆芥0.5‑1.5份，野菊花0.5‑1.5份，细辛0.5‑1.5份，青黛1‑3份，白芷2‑8份，川芎1‑5份，石菖蒲1‑3份，皂角1‑5份，玄明粉1‑3份，薄荷0.5‑1.5份，藁本0.5‑1.5份，黄芩0.5‑1.5份，紫花地丁0.5‑1.5份，藿香0.5‑1.5份，芝麻香油30‑80份。本发明提供的用于治疗急慢性鼻炎的中药膏，对各类鼻炎均有很好的治疗作用，且见效快、不易复发。

Description

一种用于治疗急慢性鼻炎的中药膏
技术领域
本发明涉及中药领域，具体涉及一种用于治疗急慢性鼻炎的中药膏。
背景技术
鼻炎分为急性鼻炎和慢性鼻炎，慢性鼻炎又包括慢性单纯性鼻炎和慢性肥厚性鼻炎。慢性单纯性鼻炎表现为鼻粘膜充血、肿胀，呈红色或暗红色，以间歇性、交替性鼻塞，鼻涕量多为主要症状；慢性肥厚性鼻炎鼻塞较重，多为持续性，有闭塞性鼻音，嗅觉减退，鼻涕为黏液性或黏脓性，不易擤出，多伴有头痛、头昏、失眠及精神萎靡等症状。以上两种慢性鼻炎一般病程较长，疲劳、感寒后症状加重，易并发耳胀、耳闭等症。急性鼻炎又称伤风鼻塞，以鼻塞、喷嚏、清涕为主要症状，通过鼻腔检查，表现为鼻粘膜充血，鼻腔内分泌物增多，起症较急，病程较短。目前对于治疗这些鼻炎的方法和药物很多，但是都存在疗效不理想，以及容易复发的问题。
发明内容
为了弥补现有技术中存在的不足，本发明提供了一种用于治疗急慢性鼻炎的中药膏，对各类鼻炎均有很好的治疗作用，且见效快、不易复发。
为了达到上述目的，本发明采用的技术方案如下：
一种用于治疗急慢性鼻炎的中药膏，包括以下重量份的组分：鹅不食草5-10份，苍耳子2-8份，辛夷2-8份，甜瓜蒂1-3份，冰片1-5份，麻黄1-3份，紫苏叶0.5-1.5份，荆芥0.5-1.5份，野菊花0.5-1.5份，细辛0.5-1.5份，青黛1-3份，白芷2-8份，川芎1-5份，石菖蒲1-3份，皂角1-5份，玄明粉1-3份，薄荷0.5-1.5份，藁本0.5-1.5份，黄芩0.5-1.5份，紫花地丁0.5-1.5份，藿香0.5-1.5份，芝麻香油30-80份。
优选的，包括以下重量份的组分：鹅不食草5份，苍耳子2份，辛夷2份，甜瓜蒂1份，冰片1份，麻黄1份，紫苏叶0.5份，荆芥0.5份，野菊花0.5份，细辛0.5份，青黛1份，白芷2份，川芎1份，石菖蒲1份，皂角1份，玄明粉1份，薄荷0.5份，藁本0.5份，黄芩0.5份，紫花地丁0.5份，藿香0.5份，芝麻香油30份。
优选的，鹅不食草8份，苍耳子5份，辛夷5份，甜瓜蒂2份，冰片3份，麻黄2份，紫苏叶1份，荆芥1份，野菊花1份，细辛1份，青黛2份，白芷5份，川芎3份，石菖蒲2份，皂角3份，玄明粉2份，薄荷1份，藁本1份，黄芩1份，紫花地丁1份，藿香1份，芝麻香油50份。
优选的，鹅不食草10份，苍耳子8份，辛夷8份，甜瓜蒂3份，冰片5份，麻黄3份，紫苏叶1.5份，荆芥1.5份，野菊花1.5份，细辛1.5份，青黛3份，白芷8份，川芎5份，石菖蒲3份，皂角5份，玄明粉3份，薄荷1.5份，藁本1.5份，黄芩1.5份，紫花地丁1.5份，藿香1.5份，芝麻香油80份。
进一步的，所述中药膏制备成液态凝胶型、冷敷凝胶型或冷敷乳膏型。
鹅不食草，具有通宣鼻窍，解毒消肿的作用，外用可以通窍排脓，刺激鼻粘膜排除积留鼻涕，以达到清洁鼻腔的作用，为君药。
苍耳子，具有散寒解表，祛风除湿，宣通鼻窍的作用，善治外感风寒，鼻渊头痛，鼻塞不闻香臭等症，是治疗鼻炎之要药，共为君药。
辛夷，具有发散风寒，宣通鼻窍的作用，能芳香通窍，治疗鼻渊头痛。是治疗鼻炎之要药，与鹅不食草、苍耳子共为君药
甜瓜蒂，外用能刺激粘膜，排出积留鼻涕，可作为佐药。
冰片，具有开窍醒神、清热解毒的作用，外用可通宣诸窍，为使药。
麻黄，具有散寒解表、通窍宣肺的作用，为臣药。
紫苏，具有散寒解表行气的作用，为佐药。
荆芥，具有散寒解表的作用，为佐药。
野菊花，具有清热解毒、散结消肿的作用，为佐药。
细辛，具有解表散寒，通窍止痛的作用，为佐药。
青黛，具有清热解毒，凉血消肿的作用，为佐药。
白芷，具有祛风解表，散寒止痛，除湿通窍，消肿排脓的作用，为臣药。
川芎，具有行气活血的作用，为佐药。
石菖蒲，具有开窍豁痰，醒神通窍的作用，为使药。
皂角，具有开窍通闭，豁痰散结的作用，为臣药。
玄明粉，具有软坚散结，清热消肿的作用，为佐药。
薄荷，疏风散热，清利头目，为佐药。
藁本，祛风散寒，除湿止痛，为佐药。
黄芩，清热燥湿，泻火止毒，为佐药。
紫花地丁，清热解毒，凉血消肿，为佐药。
藿香，芳香化湿，为佐药。
芝麻香油，解毒生肌促凝血，调和诸药，为佐药。
相对于现有技术，本发明具有以下有益技术效果：
本发明的用于治疗急慢性鼻炎的中药膏，以鹅不食草、苍耳子、辛夷共为君药，以麻黄、白芷、皂角作为臣药，再以细辛、紫苏叶、荆芥、川芎、青黛等作为佐药，最后以冰片、石菖蒲作为使药，诸药合力，共起到通宣鼻窍、拔毒排脓、开窍醒神、清洁鼻腔的作用，对各类鼻炎均有很好治疗作用。
具体实施方式
在下面的描述中阐述了很多具体细节以便于充分理解本发明。但是本发明能够以很多不同于此描述的其他方式来实施，本领域技术人员可以在不违背本发明内涵的情况下做类似推广，因此本发明不受下面公开的具体实施例的限制。
实施例1
一种用于治疗急慢性鼻炎的中药膏，包括以下重量份的组分：鹅不食草5份，苍耳子2份，辛夷2份，甜瓜蒂1份，冰片1份，麻黄1份，紫苏叶0.5份，荆芥0.5份，野菊花0.5份，细辛0.5份，青黛1份，白芷2份，川芎1份，石菖蒲1份，皂角1份，玄明粉1份，薄荷0.5份，藁本0.5份，黄芩0.5份，紫花地丁0.5份，藿香0.5份，芝麻香油30份。
实施例2
一种用于治疗急慢性鼻炎的中药膏，包括以下重量份的组分：鹅不食草8份，苍耳子5份，辛夷5份，甜瓜蒂2份，冰片3份，麻黄2份，紫苏叶1份，荆芥1份，野菊花1份，细辛1份，青黛2份，白芷5份，川芎3份，石菖蒲2份，皂角3份，玄明粉2份，薄荷1份，藁本1份，黄芩1份，紫花地丁1份，藿香1份，芝麻香油50份。
实施例3
一种用于治疗急慢性鼻炎的中药膏，包括以下重量份的组分：鹅不食草10份，苍耳子8份，辛夷8份，甜瓜蒂3份，冰片5份，麻黄3份，紫苏叶1.5份，荆芥1.5份，野菊花1.5份，细辛1.5份，青黛3份，白芷8份，川芎5份，石菖蒲3份，皂角5份，玄明粉3份，薄荷1.5份，藁本1.5份，黄芩1.5份，紫花地丁1.5份，藿香1.5份，芝麻香油80份。
上述实施例1-3的中药膏可制备成以下剂型：
液态凝胶型：将上述组分提炼成精油混合于液态凝胶中，制成鼻炎喷剂。
冷敷凝胶型：将上述组分粉碎油侵后混合于固态凝胶中，制成鼻腔冷敷凝胶。
冷敷乳膏型：将上述组分粉碎后置于乳化基质内一起乳化，制成乳膏型涂抹鼻腔。
临床病例分析
根据《中医病证诊疗标准与方剂选用》和中华医学会耳鼻喉科分会《鼻炎的诊疗原则和推荐方案》(2004年，兰州)进行病症诊断和计分。
(1)症状计分标准
表1症状记分标准表
分组记分 喷嚏* 流涕# 鼻塞 鼻痒
1分 3-5 ≤4 有意识吸气感觉 间断
2分 6-10 5-9 间歇性或交互性 蚁行感，但可忍受
3分 ≥11 ≥10 几乎全天用呼吸 蚁行感，难忍
注：*1次连续喷嚏个数；#每次撸鼻次数。
(2)体征计分标准
3分：下鼻甲与鼻底、鼻中隔紧靠，见不到中鼻甲，或中鼻甲黏膜息肉样变、息肉形成；
2分：下鼻甲与鼻中隔(或鼻底)紧靠，下鼻甲与鼻底(或鼻中隔)之间尚有小缝隙；
1分：鼻甲轻度肿胀，鼻中隔、中鼻甲尚可见。
试验过程中详细观察并记录症状体征变化，根据症状分级标准进行评分，前后对比，参照临床评价标准进行评价。
鼻炎临床表现以黏膜肿胀、分泌物增多、无明确致病微生物感染、病程持续4周以上或反复发作为特征，试验过程中详细观察并记录症状体征变化，根据症状分级标准进行评分，前后对比进行疗效判断。
试验方法：治疗组经医师指导，由患者自行带回产品进行涂抹于鼻前庭及前鼻孔周围，每天早中晚3次，每次约0.5g用量，持续28天，每7天门诊随访，观察症状、体征及不良反应，治疗期间停用其他药物，少食海鲜、辛辣刺激性等易引起过敏性食物，持续4周，评价中药鼻炎乳膏的临床疗效和安全性，其结果见表2。
表2临床病例疗效统计表
实验组 完成 显效 有效 无效 总有效
过敏性鼻炎 35 1 32 2 33(94.28％)
慢性鼻炎 38 8 27 3 35(92.11％)
鼻窦炎 40 15 20 5 35(87.50％)
实验结果表明本发明所提供的排毒乳膏治疗过敏性鼻炎总有效率达94.28％，治疗慢性鼻炎总有效率达92.11％，治疗鼻窦炎的总有效率达87.50％。
以上仅为本发明的优选实施例而已，并不用于限制本发明，尽管参照实施例对本发明进行了详细的说明，对于本领域的技术人员来说，其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换，但是凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。

Claims (5)

1.一种用于治疗急慢性鼻炎的中药膏，其特征在于，包括以下重量份的组分：鹅不食草5-10份，苍耳子2-8份，辛夷2-8份，甜瓜蒂1-3份，冰片1-5份，麻黄1-3份，紫苏叶0.5-1.5份，荆芥0.5-1.5份，野菊花0.5-1.5份，细辛0.5-1.5份，青黛1-3份，白芷2-8份，川芎1-5份，石菖蒲1-3份，皂角1-5份，玄明粉1-3份，薄荷0.5-1.5份，藁本0.5-1.5份，黄芩0.5-1.5份，紫花地丁0.5-1.5份，藿香0.5-1.5份，芝麻香油30-80份。
2.根据权利要求1所述的用于治疗急慢性鼻炎的中药膏，其特征在于，包括以下重量份的组分：鹅不食草5份，苍耳子2份，辛夷2份，甜瓜蒂1份，冰片1份，麻黄1份，紫苏叶0.5份，荆芥0.5份，野菊花0.5份，细辛0.5份，青黛1份，白芷2份，川芎1份，石菖蒲1份，皂角1份，玄明粉1份，薄荷0.5份，藁本0.5份，黄芩0.5份，紫花地丁0.5份，藿香0.5份，芝麻香油30份。
3.根据权利要求1所述的用于治疗急慢性鼻炎的中药膏，其特征在于，包括以下重量份的组分：鹅不食草8份，苍耳子5份，辛夷5份，甜瓜蒂2份，冰片3份，麻黄2份，紫苏叶1份，荆芥1份，野菊花1份，细辛1份，青黛2份，白芷5份，川芎3份，石菖蒲2份，皂角3份，玄明粉2份，薄荷1份，藁本1份，黄芩1份，紫花地丁1份，藿香1份，芝麻香油50份。
4.根据权利要求1所述的用于治疗急慢性鼻炎的中药膏，其特征在于，包括以下重量份的组分：鹅不食草10份，苍耳子8份，辛夷8份，甜瓜蒂3份，冰片5份，麻黄3份，紫苏叶1.5份，荆芥1.5份，野菊花1.5份，细辛1.5份，青黛3份，白芷8份，川芎5份，石菖蒲3份，皂角5份，玄明粉3份，薄荷1.5份，藁本1.5份，黄芩1.5份，紫花地丁1.5份，藿香1.5份，芝麻香油80份。
5.根据权利要求1-4任一项所述的用于治疗急慢性鼻炎的中药膏，其特征在于：制备成液态凝胶型、冷敷凝胶型或冷敷乳膏型。
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