CN114983909A - Repairing composition, and essence water and essence milk containing same - Google Patents
Repairing composition, and essence water and essence milk containing same Download PDFInfo
- Publication number
- CN114983909A CN114983909A CN202210841427.9A CN202210841427A CN114983909A CN 114983909 A CN114983909 A CN 114983909A CN 202210841427 A CN202210841427 A CN 202210841427A CN 114983909 A CN114983909 A CN 114983909A
- Authority
- CN
- China
- Prior art keywords
- extract
- component
- composition
- humectant
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 93
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 73
- 239000008267 milk Substances 0.000 title claims abstract description 28
- 210000004080 milk Anatomy 0.000 title claims abstract description 28
- 235000013336 milk Nutrition 0.000 title claims abstract description 28
- 239000000284 extract Substances 0.000 claims abstract description 158
- 239000003906 humectant Substances 0.000 claims abstract description 49
- 239000000419 plant extract Substances 0.000 claims abstract description 27
- 239000002562 thickening agent Substances 0.000 claims abstract description 18
- 241000628997 Flos Species 0.000 claims abstract description 11
- 229920001503 Glucan Polymers 0.000 claims abstract description 8
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 5
- 239000002994 raw material Substances 0.000 claims description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 25
- 239000006210 lotion Substances 0.000 claims description 13
- 241000157280 Aesculus hippocastanum Species 0.000 claims description 12
- 241001076416 Dendrobium tosaense Species 0.000 claims description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- 235000010181 horse chestnut Nutrition 0.000 claims description 12
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 11
- 235000011187 glycerol Nutrition 0.000 claims description 11
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 11
- 229940038580 oat bran Drugs 0.000 claims description 10
- 230000008439 repair process Effects 0.000 claims description 9
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 8
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims description 8
- 229960003237 betaine Drugs 0.000 claims description 8
- YPFDHNVEDLHUCE-UHFFFAOYSA-N propane-1,3-diol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims description 8
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 claims description 7
- 241000219357 Cactaceae Species 0.000 claims description 7
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 7
- 229940100524 ethylhexylglycerin Drugs 0.000 claims description 7
- 239000003755 preservative agent Substances 0.000 claims description 7
- 230000002335 preservative effect Effects 0.000 claims description 7
- 239000003963 antioxidant agent Substances 0.000 claims description 6
- 230000003078 antioxidant effect Effects 0.000 claims description 6
- 239000003974 emollient agent Substances 0.000 claims description 6
- 239000001228 rosa centifolia flower Substances 0.000 claims description 6
- 229940046326 rosa centifolia flower extract Drugs 0.000 claims description 6
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims description 5
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 4
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims description 4
- 244000162450 Taxus cuspidata Species 0.000 claims description 3
- 235000009065 Taxus cuspidata Nutrition 0.000 claims description 3
- 229960005150 glycerol Drugs 0.000 claims description 2
- 240000009022 Smilax rotundifolia Species 0.000 claims 2
- 235000003205 Smilax rotundifolia Nutrition 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 abstract description 14
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- 238000002360 preparation method Methods 0.000 description 39
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- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 6
- 238000004140 cleaning Methods 0.000 description 5
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- 235000015097 nutrients Nutrition 0.000 description 5
- 239000012466 permeate Substances 0.000 description 5
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- 238000003756 stirring Methods 0.000 description 5
- MXOAEAUPQDYUQM-QMMMGPOBSA-N (S)-chlorphenesin Chemical compound OC[C@H](O)COC1=CC=C(Cl)C=C1 MXOAEAUPQDYUQM-QMMMGPOBSA-N 0.000 description 4
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 4
- 229920000742 Cotton Polymers 0.000 description 4
- 230000032683 aging Effects 0.000 description 4
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical group NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 4
- 229960003993 chlorphenesin Drugs 0.000 description 4
- 238000007599 discharging Methods 0.000 description 4
- 239000000839 emulsion Substances 0.000 description 4
- 238000011049 filling Methods 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 229960005323 phenoxyethanol Drugs 0.000 description 4
- 206010015150 Erythema Diseases 0.000 description 3
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- 230000009286 beneficial effect Effects 0.000 description 3
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- 229920001285 xanthan gum Polymers 0.000 description 3
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- 235000010493 xanthan gum Nutrition 0.000 description 3
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 description 2
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 2
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 2
- 244000075850 Avena orientalis Species 0.000 description 2
- 235000007319 Avena orientalis Nutrition 0.000 description 2
- 244000035851 Chrysanthemum leucanthemum Species 0.000 description 2
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 2
- 241001523681 Dendrobium Species 0.000 description 2
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical group C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 2
- 240000005067 Jasminum grandiflorum Species 0.000 description 2
- 235000004412 Jasminum grandiflorum Nutrition 0.000 description 2
- 235000010254 Jasminum officinale Nutrition 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 229960000458 allantoin Drugs 0.000 description 2
- 230000003266 anti-allergic effect Effects 0.000 description 2
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- 239000003795 chemical substances by application Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 231100000321 erythema Toxicity 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 210000003630 histaminocyte Anatomy 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 150000004804 polysaccharides Polymers 0.000 description 2
- 229940068968 polysorbate 80 Drugs 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical group [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 2
- 229940103091 potassium benzoate Drugs 0.000 description 2
- 235000010235 potassium benzoate Nutrition 0.000 description 2
- 239000004300 potassium benzoate Substances 0.000 description 2
- 239000004302 potassium sorbate Substances 0.000 description 2
- 235000010241 potassium sorbate Nutrition 0.000 description 2
- 229940069338 potassium sorbate Drugs 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- -1 skin conditioner Substances 0.000 description 2
- 229940047670 sodium acrylate Drugs 0.000 description 2
- 229950004959 sorbitan oleate Drugs 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 230000001502 supplementing effect Effects 0.000 description 2
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 1
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical group CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 241000132023 Bellis perennis Species 0.000 description 1
- 229920002498 Beta-glucan Polymers 0.000 description 1
- 235000003880 Calendula Nutrition 0.000 description 1
- 240000001432 Calendula officinalis Species 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical group CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 244000236658 Paeonia lactiflora Species 0.000 description 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 1
- 235000006751 Platycodon Nutrition 0.000 description 1
- 244000274050 Platycodon grandiflorum Species 0.000 description 1
- 240000004534 Scutellaria baicalensis Species 0.000 description 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 241001369613 Stephania tetrandra Species 0.000 description 1
- 206010043189 Telangiectasia Diseases 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- BQMNFPBUAQPINY-UHFFFAOYSA-N azane;2-methyl-2-(prop-2-enoylamino)propane-1-sulfonic acid Chemical compound [NH4+].[O-]S(=O)(=O)CC(C)(C)NC(=O)C=C BQMNFPBUAQPINY-UHFFFAOYSA-N 0.000 description 1
- 230000001054 cortical effect Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 229940067866 dandelion extract Drugs 0.000 description 1
- 235000020691 dandelion extract Nutrition 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- 229940051257 eucalyptus globulus leaf extract Drugs 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000008131 herbal destillate Substances 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical compound CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 229930189914 platycodon Natural products 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- FWFUWXVFYKCSQA-UHFFFAOYSA-M sodium;2-methyl-2-(prop-2-enoylamino)propane-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)CC(C)(C)NC(=O)C=C FWFUWXVFYKCSQA-UHFFFAOYSA-M 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 239000001845 taraxacum officinale leaf extract Substances 0.000 description 1
- 229940104261 taurate Drugs 0.000 description 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
- 208000009056 telangiectasis Diseases 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The application relates to the field of sensitive muscle skin care products, in particular to a repairing composition and essence water and essence milk containing the composition. The repairing composition comprises a component A, a component B, a component C and glucan; the component A comprises herba Dendrobii stem extract, folium Taxilli extract, radix Glycytthizae extract, other plant extracts, humectant A, and water; the component B comprises extract of flos Spiraeae Fortunei, other flower extract, humectant A, thickener A, antibacterial agent, and water; the component C comprises radix Ophiopogonis extract, Scutellariae radix extract, radix Paeoniae extract, additional plant extract, humectant A, and water. The repairing composition can be used for preparing essence water and essence milk. The composition is suitable for sensitive muscles and can be used for a long time.
Description
Technical Field
The application relates to the field of sensitive muscle skin care products, in particular to a repairing composition and essence water and essence milk containing the composition.
Background
The skin is the first barrier of the human body from the external environment, and it protects various internal barriers and organs from external physical, mechanical, chemical and pathogenic microorganisms. The skin barrier is mainly composed of many substances such as sebaceous membranes, keratin in the stratum corneum, lipids, etc.
The term "sensitive muscle" in the mouth, known as "sensitive skin", refers to a highly reactive state of the skin under physiological or pathological conditions, which occurs mainly in the face. The clinical manifestations of sensitive muscles are mainly burning, stabbing pain, itching and tightness when skin is stimulated by physical, chemical or mental factors, and sometimes accompanied by erythema, desquamation and telangiectasia.
At present, the most effective solution for skin sensitivity is to use drugs, but drugs with drug resistance are easy to generate after long-term use, which can cause the situation that sensitive muscles of users cannot be relieved. Or some hormones in medicines, and long-term use of the hormones can cause hormone-dependent dermatitis. Therefore, improvement is yet to be achieved.
Disclosure of Invention
In order to develop a repair product for sensitive muscles, which can be used for a long time, the application provides a repair composition and essence water and essence milk containing the composition.
In a first aspect, the present application provides a repairing composition, which adopts the following technical scheme:
the repairing composition is prepared from the following raw materials in parts by weight: 4-6 parts of component A, 2-4 parts of component B, 1-3 parts of component C and 0.2-0.6 part of glucan;
the component A is prepared from the following raw materials in percentage by mass: 1.5-2.5% of dendrobium officinale stem extract, 4.8-6.0% of taxus cuspidata leaf extract, 4.5-5.8% of glycyrrhiza glabra root extract, 10-14% of other plant extracts, 0.5-1.2% of humectant A and water which are supplemented to 100%;
the component B is prepared from the following raw materials in percentage by mass: 0.8-1.5% of vegetarian square flower extract, 1.5-3.0% of other flower extract, 30-45% of humectant A, 0.12-0.35% of thickener A, 0.35-0.5% of antibacterial agent and water to 100%;
the component C is prepared from the following raw materials in percentage by mass: 2.5-3.5% of radix ophiopogonis extract, 0.8-1.5% of radix scutellariae extract, 1.2-2.2% of radix paeoniae extract, 8-12% of additional plant extract, 48-55% of humectant A and water which is supplemented to 100%.
The composition is prepared by combining a plurality of specific plant extracts together, and the plant extracts are used as active ingredients, so that the dependence of the product on chemical synthetics is greatly reduced, the safety of the product is greatly improved, and sensitive muscles can be used safely. Moreover, the skin has higher acceptance of natural plant extracts than chemical synthetics, has good use feeling, and does not generate dependence feeling after long-term use.
By adopting the technical scheme, under the specific proportion of the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract, a plurality of macromolecules and micromolecules with different sizes act on the skin of a user together, and permeate into different skin layers on the skin layer by layer, so that the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract have good permeability and efficacy. So that various externally supplemented nutrient substances can deeply permeate into the skin cortex, nourish the skin and supplement various nutrient substances lacking in the skin, thereby repairing the skin barrier. Under the condition of long-term use with daily accumulation and monthly service, the face is ruddy, the skin is smooth and not easy to be reddened, and the skin barrier is in a relatively firm condition, so that the resistance effect to the severe environment is improved.
Inflammation relief treatment is also one of the important parts of repair. Under the specific matching, the inventor finds that the composition acts in essence water and essence milk, has more remarkable treatment effects on inflammation and analgesia of sensitive muscle users, and further plays a good repairing role.
Preferably, the other plant extracts comprise one or more of tetrandra root extract, aesculus hippocastanum extract and smilax glabra root extract;
the other flower extract comprises one or more of flos Rosae Davuricae extract and flos Chrysanthemi extract;
the additional plant extract comprises one or more of radix et caulis Opuntiae Dillenii extract and oat bran extract.
Preferably, in the component a, the other plant extracts include tetrandra root extract, aesculus hippocastanum extract and smilax glabra root extract, and the mass ratio of the tetrandra root extract, the aesculus hippocastanum extract, the smilax glabra root extract to the glycyrrhiza glabra root extract is 0.33: 1: 1: 1;
the other flower extracts comprise rosa centifolia flower extract and chrysanthemum flower extract, and the mass ratio of the rosa centifolia flower extract, the chrysanthemum flower extract and the square flower extract is 1: 1: 1;
the additional plant extracts comprise cactus extract and oat bran extract, and the mass ratio of the cactus extract to the oat bran extract to the radix ophiopogonis extract is 7: 3: 3.
by adopting the technical scheme, the prepared composition acts in products such as essence water, essence milk, essence cream and the like, so that the release of inflammation media is resisted strongly, and the damage of the inflammation media to normal cells is inhibited; reducing the water loss of the skin, enhancing the barrier function of the skin, improving the self-protection capability of the skin and reducing the sensitivity; the compound preparation can eliminate excessive free radicals, weaken the damage of the free radicals to cell membranes of mast cells and basophils, and achieve the effects of anti-allergy and relieving itching, thereby achieving good repairing effect.
Preferably, the humectant A comprises one or more of 1, 2-hexanediol, ethylhexyl glycerin, glycerin and butanediol.
Preferably, the humectant A in the component A comprises 0.4-0.8% of 1, 2-hexanediol and 0.1-0.4% of ethylhexyl glycerin in percentage by mass of the total mass of the component A; the humectant A of the component B comprises glycerin accounting for 30-45% of the total mass of the component B; the humectant A in the component C comprises butanediol accounting for 48-55% of the total mass of the component C.
Preferably, the humectant A in the component A comprises 0.5 percent of 1, 2-hexanediol and 0.2 percent of ethylhexyl glycerin in percentage by mass of the total mass of the component A; the humectant A of the component B comprises glycerin accounting for 40 percent of the total mass of the component B; the humectant A in the component C comprises butanediol accounting for 50 percent of the total mass of the component C.
Oil, sweat and fat from the skin jointly form a sebum membrane of the skin, improper cleaning and excessive cleaning are main reasons for the damage of the sebum membrane, particularly for dry sensitive muscles, the sebum membrane is poor in state, and moisture retention is required to assist in repairing the sebum membrane.
A prerequisite for this is that the user uses the product containing the composition after cleansing and application of a toner. At this point, the user's surface has been replenished with a quantity of extraneous water.
Firstly, under the common cooperation of the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract, the original way of forming a film and locking water by macromolecules is widened to the way of absorbing moisture and coexisting by micromolecules on the original basis, and the repairing of the sebaceous membrane is assisted from multiple aspects.
Moreover, on the basis, the skin care product is matched with a humectant of a specific kind, so that the effects of the dendrobium polysaccharide and the ophiopogon polysaccharide on the skin are further promoted. Specifically, the polar groups of the polysaccharide form hydrogen bonds with water molecules to bind moisture, thereby providing skin with engorgement moisture. Moreover, the dendrobium polysaccharide and the ophiopogon polysaccharide form a uniform film on the surface of the skin more quickly, so that the speed of supplementing water from the outside and evaporating the skin from the water in the air is reduced. The water is locked and supplemented, and the long-term water moistening is kept, so that good repairing conditions are provided for the sebum membrane, and the repairing is carried out under mild and proper conditions.
In a second aspect, the application provides a serum containing the composition, and the following technical scheme is adopted:
the essence water containing the composition is prepared from the following raw materials in percentage by mass: 8-12% of humectant B, 0.1-0.5% of preservative, 0.2-0.5% of thickening agent B, 0.1-0.3% of pH regulator, 0.1-0.3% of skin conditioner, 9-12% of composition and water to 100%.
Preferably, the humectant B comprises one or more of 1, 3-propylene glycol and betaine.
Preferably, the preparation process of the essence water containing the composition comprises the following steps:
step 1): mixing water, humectant B, thickener B, skin conditioner, and 15-25% antiseptic uniformly, adjusting temperature to 80-90 deg.C, and keeping the temperature for 18-30min to obtain semi-finished product of water.
Step 2): cooling to 32-42 deg.C, adding pH regulator, composition and the rest antiseptic into the semi-finished product, and stirring;
and step 3): and filtering and discharging after the plate is qualified to obtain a water material body, and filling the water material body after aging and inspection to obtain a finished product.
By adopting the technical scheme, the composition is prepared by being mixed into the essence water, and a specific humectant is selected for auxiliary matching. The specific humectant lays a foundation for basic moisturizing, and the humectant permeates into different skin layers of the skin along with the composition to enable the skin to be full of moisture. The composition has the effect of strongly locking water while supplementing water by cooperating with the humectant, so that the sebum membrane is repaired.
In a third aspect, the application provides a serum containing the composition, and the following technical scheme is adopted:
the essence milk containing the composition is prepared from the following raw materials in percentage by mass: 10-13% of humectant C, 2-6% of emollient, 1.0-1.5% of thickener C, 0-0.6% of antioxidant, 0.1-0.5% of preservative, 0.1-0.3% of skin conditioner, 9-12% of composition and water to 100%.
Preferably, the humectant C comprises one or more of propylene glycol, glycerin and betaine.
Preferably, the essence milk containing the composition comprises the following preparation methods:
step 01): mixing water, humectant C, 45-55% thickener, skin conditioner, and 15-25% antiseptic, stirring, adjusting temperature to 80-90 deg.C, and keeping the temperature for 18-30min to obtain semi-finished product of milk;
step 02): adjusting temperature to 68-78 deg.C, adding emollient, antioxidant and the rest thickener into the semi-finished product, and homogenizing for 4-8 min;
step 03): continuously adjusting the temperature to 35-45 deg.C, adding the composition and the rest antiseptic, and mixing;
step 04): and filtering and discharging after the plate is qualified to obtain an emulsion body, and filling the emulsion body after aging and inspection to obtain a finished product.
Through adopting above-mentioned technical scheme, essence milk texture can be thicker and heavier than essence water, and it has good long-term moisturizing effect, but essence milk produces the stifled skin sense easily. The composition is applied to the essence milk and is matched with a specific humectant, so that the refreshing feeling of the essence milk is improved. The composition has rapid penetration function, so that the essence milk can penetrate into the skin before the skin feeling is stuffy, and the essence milk can be rapidly absorbed by the skin and then forms a uniform film for water locking. The refreshing feeling slows down the situation of acne, is beneficial to repairing sensitive muscles and improves the good use experience.
In summary, the present application has the following beneficial effects:
1. under the specific proportion of the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract, various macromolecules and small molecules with different sizes act on the skin of a user together, and permeate into different skin layers on the skin layer by layer, so that the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract have good permeability and efficacy. So that various externally supplemented nutrient substances can deeply permeate into the skin cortex, nourish the skin and supplement various nutrient substances lacking in the skin, thereby repairing the skin barrier. Under the condition of long-term use, the face is ruddy, the skin is smooth and not easy to be reddened, and the skin barrier is in a relatively firm condition, so that the resistance effect on the severe environment is improved.
2. The prepared composition acts in products such as essence water, essence milk, essence cream and the like, strongly resists the release of inflammation media, and inhibits the damage of the inflammation media to normal cells; reducing the water loss of the skin, enhancing the barrier function of the skin, improving the self-protection capability of the skin and reducing the sensitivity; the compound preparation can eliminate excessive free radicals, weaken the damage of the free radicals to cell membranes of mast cells and basophils, and achieve the effects of anti-allergy and relieving itching, thereby achieving good repairing effect.
3. Under the cooperation of the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract, water is locked and supplemented, and long-acting moisture is kept, so that good repairing conditions are provided for a sebum membrane, and repairing is carried out under mild and appropriate conditions.
Detailed Description
The present application will be described in further detail with reference to examples.
The plant extracts used in the following preparation examples are all commercially available dry products, and after being purchased, the plant extracts are all washed with water and dried, and then put into use; the raw materials used in the other preparation examples, examples and comparative examples are all commercial products.
Preparation example
Preparation example 1
The repairing composition is prepared from the following raw materials: 5kg of component A, 3kg of component B, 2kg of component C and 0.5kg of glucan. And putting the component A, the component B, the component C and the glucan into a stirring kettle, and uniformly mixing to obtain the composition.
The component A comprises the following raw materials: herba Dendrobii (Dendrobii officiniale) stem extract, Taxus cuspidata (Taxuscuspirata) leaf extract, Glycyrrhiza glabra (Glycyrrhiza glabra) root extract, other plant extracts, humectant A and water. Mixing the above materials to obtain component A.
The other plant extracts are radix Stephaniae Japonicae (STEPHANIATETRANDRA) extract, Aesculus hippocastanum (Aesculus hippocastanum) extract and rhizoma Smilacis Glabrae (Smilaxglaxlaba) root extract. The mass ratio of the tetrandra root extract, the aesculus hippocastanum extract, the smilax glabra root extract to the glycyrrhiza glabra root extract is 0.33: 1: 1: 1.
the component B comprises the following raw materials: extract of flower of Jasminum officinale (Jasminum officinale), extract of other flower, humectant A, thickener A, antibacterial agent and water. Mixing the above materials to obtain component B.
The other flower extract is flos Rosae Multiflorae (Rosacetifolia) flower extract and Bellis perennis (Bellperennis) flower extract. The mass ratio of the rosa centifolia flower extract, the marguerite flower extract and the vegetarian square flower extract is 1: 1: 1.
the thickening agent A is xanthan gum; the antibacterial agent is potassium benzoate and potassium sorbate, and the mass ratio of the potassium benzoate to the potassium sorbate is 1: 1.
the component C comprises the following raw materials: radix Ophiopogonis (Ophiopogonjaponicas) root extract, Scutellariae radix (Scutellaria baicalensis) root extract, radix Paeoniae (Paeonia lactiflora) root extract, additional plant extract, humectant A and water. Mixing the above materials to obtain component C.
The additional plant extract is radix et caulis Opuntiae Dillenii (Opuntiadadilenii) extract, and oat (AVENASATIVA) bran extract. The mass ratio of the cactus extract to the oat bran extract to the ophiopogon root extract is 7: 3: 3.
the humectant A in the component A is 1, 2-hexanediol and ethylhexylglycerin, wherein the 1, 2-hexanediol accounts for 0.5 percent of the total mass of the component A, and the ethylhexylglycerin accounts for 0.2 percent of the total mass of the component A.
The humectant A of the component B comprises glycerin which accounts for 40 percent of the total mass of the component B.
The humectant A in the component C comprises butanediol, and the butanediol accounts for 50% of the total mass of the component C.
The glucan is beta-glucan.
Preparation example 2
A repairing composition which is different from preparation example 1 in that the amount of component A used is 4kg, the amount of component B used is 2kg, the amount of component C used is 1kg, and the amount of glucan used is 0.2kg.
The amounts of the respective raw materials used in component A, B, C were varied, and tables 1 to 3 were referred to.
Preparation example 3
A repairing composition which is different from preparation example 1 in that 6kg of component A, 4kg of component B, 3kg of component C and 0.6kg of glucan were used.
The amounts of the respective raw materials used in component A, B, C were varied, and tables 1 to 3 were referred to.
TABLE 1 component A
TABLE 2 component B
TABLE 3 component C
Preparation example 4
A repairing composition which is different from the preparation example 1 in that,
in the component A, the other plant extracts are a tetrandra root extract, a aesculus hippocastanum extract and a smilax glabra root extract, and the mass ratio of the tetrandra root extract to the aesculus hippocastanum extract to the smilax glabra root extract is 1: 0.5: 0.8: 1; the amount of water is adjusted accordingly. The usage amount of the tetrandra root extract is 5.5kg, the usage amount of the aesculus hippocastanum extract is 2.8kg, the usage amount of the smilax glabra root extract is 4.4kg, and the usage amount of the glycyrrhiza glabra root extract is 5.5 kg.
In component B, the other flower extracts are flos Rosae Davuricae extract and flos Chrysanthemi extract. The mass ratio of the rosa centifolia flower extract, the marguerite flower extract and the vegetarian square flower extract is 0.5: 2: 1; the amount of water is adjusted accordingly. The usage amount of flos Rosae Davuricae extract is 0.5kg, the usage amount of flos Chrysanthemi extract is 2kg, and the usage amount of flos Przewalskii extract is 1 kg.
The additional plant extract is radix et caulis Opuntiae Dillenii extract and oat bran extract. The mass ratio of the cactus extract to the oat bran extract to the ophiopogon root extract is 1: 3: 1; the amount of water is adjusted accordingly. The cactus extract is used in an amount of 3kg, the oat bran extract is used in an amount of 9kg, and the ophiopogon root extract is used in an amount of 3 kg.
Preparation example 5
A repairing composition is different from the preparation example 1 in that the other plant extract in the component A is a platycodon root extract, the using amount is 14kg, and the using amount of water is adjusted correspondingly. The other flower extract in component B is calendula extract; the amount of water is adjusted accordingly. The additional plant extract in component C is herba Portulacae extract; the amount of water is adjusted accordingly.
The humectant A is glycerol.
Preparation example 6
A repairing composition is different from the preparation example 1 in that the dendrobium officinale stem extract in the component A is replaced by the eucalyptus globulus leaf extract with equal mass.
Preparation example 7
A repairing composition, which is different from preparation example 1 in that the extract of the vegetarian square flower in component A is replaced with an equal mass of dandelion extract.
Preparation example 8
A repairing composition, which is different from preparation example 1 in that the extract of the vegetarian squareha in component A is replaced with an equal mass of the extract of grape seeds.
Preparation example 9
A repairing composition which is different from preparation example 1 in that the amount of component A used is 1kg, the amount of component B used is 6kg, and the amount of component C used is 3.5 kg.
Examples
Example 1
An essential lotion comprising the composition, humectant B, preservative, thickener B, pH regulator, skin conditioner, composition and water.
The humectant B is 1, 3-propylene glycol and betaine, the usage amount of the 1, 3-propylene glycol is 8kg, and the usage amount of the betaine is 1.2 kg.
The antiseptic is mixture of phenoxyethanol, 1, 2-hexanediol and chlorphenesin, and methyl hydroxybenzoate. The usage amount of phenoxyethanol is 0.21kg, the usage amount of 1, 2-hexanediol is 0.1kg, and the usage amount of chlorphenesin is 0.09 kg. The amount of methyl hydroxybenzoate used was 0.1 kg.
The thickener B is xanthan gum and carbomer, wherein the usage amount of the xanthan gum is 0.2kg, and the usage amount of the carbomer is 0.18 kg.
The pH regulator is arginine.
The skin conditioning agent is allantoin.
The composition used was that of preparation example 1.
The specific amounts of the remaining raw materials are shown in Table 4.
The embodiment of the application also discloses a preparation method of the essence water containing the composition, which comprises the following steps:
step 1): cleaning emulsifying pots and various using equipment.
Step 2): mixing water, humectant B, thickener B, skin conditioner and methyl hydroxybenzoate uniformly, adjusting temperature to 80 deg.C, and keeping the temperature for 20min to obtain semi-finished product.
Step 3): cooling to 40 deg.C, adding pH regulator, composition and the rest antiseptic into the semi-finished product, and stirring.
Step 4): filtering and discharging after the board is qualified to obtain a water body, aging the water body for 24 hours, sampling and inspecting, and performing physical and chemical and microbial detection on a semi-finished product.
Step 5): and after the detection is qualified, filling, packaging and code spraying are carried out within a week to obtain a finished product.
Example 2
An essence lotion containing the composition is different from the essence lotion of example 1 in the amount of raw materials, and the composition of preparation example 2 is adopted, and the details are shown in Table 4.
A method for preparing essence water containing the composition, which is different from the method of example 1,
in the step 2), the temperature is adjusted to 90 ℃, and the temperature is kept for 18 min.
In step 3), the temperature is adjusted to 42 ℃.
Example 3
An essence lotion containing the composition is different from the essence lotion of example 1 in the amount of raw materials, and the composition is prepared in preparation example 3, and is specifically shown in Table 4.
A method for preparing essence water containing the composition, which is different from the method of example 1,
in the step 2), the temperature is adjusted to 80 ℃, and the temperature is kept for 30 min.
In step 3), the temperature is adjusted to 32 ℃.
TABLE 4
Example 4
An essential lotion comprising the composition is different from example 1 in that the composition is prepared in accordance with preparation example 4.
Example 5
An essence lotion comprising the composition was different from example 1 in that the composition used in preparation example 5.
Example 6
An essence milk containing the composition comprises the following raw materials: humectant C, emollient, thickener C, antioxidant, preservative, skin conditioner, composition, and water.
The humectant C is propylene glycol, glycerol, and betaine. The amount of propylene glycol used was 5kg, the amount of glycerin used was 5kg, and the amount of betaine used was 1.2 kg.
The emollient is cyclohexasiloxane, cyclopentadimethylsiloxane, polydimethylsiloxane, caprylic capric triglyceride. The usage amount of the cyclohexasiloxane is 0.66kg, the usage amount of the cyclopentadecyldimethyl siloxane is 1.34kg, the usage amount of the dimethyl polysiloxane is 1kg, and the usage amount of the caprylic capric triglyceride is 1 kg.
The thickener C is a mixture of sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80, water and sorbitan oleate, and an acryloyldimethyl taurate/VP copolymer. The amount of the sodium acrylate/sodium acryloyldimethyl taurate copolymer was 0.225kg, the amount of isohexadecane was 0.135kg, the amount of polysorbate-80 was 0.045kg, the amount of water was 0.18kg, the amount of sorbitan oleate was 0.015kg, and the amount of the ammonium acryloyldimethyl taurate/VP copolymer was 0.6kg.
The antioxidant is tocopherol acetate.
The antiseptic is mixture of phenoxyethanol, 1, 2-hexanediol and chlorphenesin, and methyl hydroxybenzoate. The usage amount of the phenoxyethanol is 0.21kg, the usage amount of the 1, 2-hexanediol is 0.1kg, and the usage amount of the chlorphenesin is 0.09 kg. The amount of methyl hydroxybenzoate used was 0.1 kg.
The skin conditioning agent is allantoin.
The composition used was that of preparation example 1.
The specific amounts of the remaining raw materials are shown in Table 5.
The application also discloses a preparation method of the essence milk containing the composition, which comprises the following steps:
step 01): cleaning emulsifying pots and various using equipment.
Step 02): mixing water, humectant C, acryloyl dimethyl ammonium taurate/VP copolymer, skin conditioner and methyl hydroxybenzoate together, stirring, adjusting temperature to 80 deg.C, and keeping the temperature for 20min to obtain semi-finished product of milk.
Step 03): adjusting temperature to 75 deg.C, adding emollient, antioxidant and the rest thickener into the semi-finished milk product, and homogenizing for 5 min.
Step 04): the temperature is further adjusted to 40 ℃, and the composition and the rest of the preservative are added and mixed uniformly.
Step 05): filtering and discharging after the plate is qualified to obtain an emulsion body, aging the emulsion body for 24 hours, sampling and inspecting, and performing physical and chemical and microbial detection on a semi-finished product.
Step 06): and after the detection is qualified, filling, packaging and code spraying are carried out within a week to obtain a finished product.
Example 7
An essential milk containing the composition is different from the essential milk in example 6 in the amount of each raw material, and is specifically shown in table 5.
The composition was prepared as in preparation example 2.
Example 8
An essential milk containing the composition is different from the essential milk in example 6 in the amount of the raw materials, and the detailed description is shown in table 5.
The composition used was that of preparation 3.
TABLE 5
Comparative example
Comparative example 1
An essential lotion comprising the composition is different from example 1 in that the composition is prepared in preparation example 6.
Comparative example 2
An essence lotion comprising the composition was different from example 1 in that the composition used in preparation example 7.
Comparative example 3
An essence lotion comprising the composition was different from example 1 in that the composition used in preparation example 8.
Comparative example 4
An essence lotion comprising the composition was different from example 1 in that the composition used in preparation example 9.
Performance test
1. And (3) detecting the water content of the skin: 24 slightly sensitive muscle volunteers aged 25-35 were selected, two volunteers in one group, and one of the products of examples 1-8 and comparative examples 1-4 was used in one group. During the test period, the volunteers respectively use the corresponding products once every morning and evening after basic face cleaning and toner, and other skin care products and cosmetics are not additionally used. The skin moisture content was measured with a skin moisture content tester before use, 1h after the first use, and 8 weeks after use.
2. And (3) penetration effect: 10 pieces of cotton pads are prepared and piled. 2ml of the samples of examples 1-5 and comparative examples 1-4 are taken and dropped on the surface of the cotton pads from top to bottom, and the time required for dropping the liquid on the surface of the first cotton pad without flowing is recorded by visual observation; the next piece of cotton pad from top to bottom was then examined for penetration.
3. Appearance of sensitive muscles, feeling of use: the first volunteers were observed for the face after 8 weeks of use and recorded for erythema, redness, rash, etc. Meanwhile, the volunteers are asked to feel the use, and the conditions of absorption speed, moisture retention, moistening degree and the like are recorded.
The above assay data are detailed in Table 6.
TABLE 6-1
TABLE 6-2
According to the detection data of the examples 1-8 in the table 6, the water content of the face is greatly improved after the products of the examples 1-8 are applied to the face of a volunteer for 1h, which shows that the products have good water replenishing effect. After the face mask is continuously used for 8 weeks, the water content of the face is greatly improved compared with that before the face mask is used, which shows that the product has good water locking effect and the effect of improving the skin water wettability, and provides a good environment for repairing the sebum membrane. The excellent effect of the products of examples 1-8 on skin repair is further verified by combining the detection data of appearance and use feeling, the volunteers have good use experience, the sensitive muscles of the volunteers are also relieved, and the health state is presented.
The method is characterized in that under the specific proportion of the dendrobium officinale stem extract, the vegetarian square flower extract and the ophiopogon root extract, a moisture retention mode of micromolecule moisture absorption coexistence is realized while water is retained in macromolecular film forming, so that the skin is kept to be long-acting moist, and the sebaceous film is repaired under a proper condition.
As can be seen from the measured data of the permeation effects of examples 1 to 5 in Table 6-1, the essential waters of examples 1 to 5 have a rapid permeation rate and also have a good permeation effect. The specific proportion of the dendrobium officinale stem extract, the vegetarian square flower extract and the radix ophiopogonis extract shows that the combination of various molecules is favorable for permeation, so that the nutrient substances are supplemented to different cortical nourishing skins, and the skins are also favorable for repairing.
As can be seen from comparison of the test data of examples 1-3 and examples 4-5 in Table 6, further limiting the amount of component A, B, C and the selection of raw materials is beneficial to improving the product effect to some extent.
According to the comparison of the test data of example 1 and comparative examples 1-3 in table 6, the water content of the face of the volunteer is improved to a smaller extent than that of the volunteer before use 1h and 8 weeks after the volunteer uses the product of comparative examples 1-3, and the improvement of the face is far from the improvement of the volunteer brought by example 1. The preparation method is characterized in that the prepared composition can be applied to skin care products to achieve a good repair effect only by the common cooperation of the dendrobium officinale stem extract, the vegetarian square flower extract and the ophiopogon root extract, and the three extracts are not acceptable. And the detection data of the comparative example 4 are combined, so that the three components can be matched under a specific use amount to achieve an ideal effect.
The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.
Claims (9)
1. The repairing composition is characterized by being prepared from the following raw materials in parts by mass: 4-6 parts of component A, 2-4 parts of component B, 1-3 parts of component C and 0.2-0.6 part of glucan;
the component A is prepared from the following raw materials in percentage by mass: 1.5-2.5% of dendrobium officinale stem extract, 4.8-6.0% of taxus cuspidata leaf extract, 4.5-5.8% of glycyrrhiza glabra root extract, 10-14% of other plant extracts, 0.5-1.2% of humectant A and water which is supplemented to 100%;
the component B is prepared from the following raw materials in percentage by mass: 0.8-1.5% of vegetarian square flower extract, 1.5-3.0% of other flower extract, 30-45% of humectant A, 0.12-0.35% of thickener A, 0.35-0.5% of antibacterial agent and water to 100%;
the component C is prepared from the following raw materials in percentage by mass: 2.5-3.5% of radix ophiopogonis extract, 0.8-1.5% of radix scutellariae extract, 1.2-2.2% of radix paeoniae extract, 8-12% of additional plant extract, 48-55% of humectant A and water which are supplemented to 100%.
2. The repair composition according to claim 1, characterized in that: the other plant extract comprises one or more of radix Stephaniae Japonicae extract, Aesculus hippocastanum extract, and rhizoma Smilacis Glabrae extract;
the other flower extract comprises one or more of flos Rosae Davuricae extract and flos Chrysanthemi extract;
the additional plant extract comprises one or more of radix et caulis Opuntiae Dillenii extract and oat bran extract.
3. The repair composition of claim 2, wherein: in the component A, the other plant extracts comprise a tetrandra root extract, a aesculus hippocastanum extract and a glabrous greenbrier rhizome extract, and the mass ratio of the tetrandra root extract to the aesculus hippocastanum extract to the glabrous greenbrier rhizome extract is 0.33: 1: 1: 1;
the other flower extracts comprise rosa centifolia flower extract and chrysanthemum flower extract, and the mass ratio of the rosa centifolia flower extract, the chrysanthemum flower extract and the square flower extract is 1: 1: 1;
the additional plant extracts comprise cactus extract and oat bran extract, and the mass ratio of the cactus extract to the oat bran extract to the radix ophiopogonis extract is 7: 3: 3.
4. the repair composition according to claim 1, characterized in that: the humectant A comprises one or more of 1, 2-hexanediol, ethylhexyl glycerin, glycerin and butanediol.
5. The repair composition according to claim 1, characterized in that: the humectant A in the component A comprises 0.5 percent of 1, 2-hexanediol and 0.2 percent of ethylhexyl glycerin in percentage by mass of the total component A; the humectant A of the component B comprises glycerin accounting for 40 percent of the total mass of the component B; the humectant A in the component C comprises butanediol accounting for 50 percent of the total mass of the component C.
6. The essence lotion containing the composition is characterized by being prepared from the following raw materials in percentage by mass: 8-12% of humectant B, 0.1-0.5% of preservative, 0.2-0.5% of thickening agent B, 0.1-0.3% of pH regulator, 0.1-0.3% of skin conditioner, 9-12% of composition and water to 100%; the composition described in any of examples 1 to 5 was used.
7. The essence lotion comprising the composition according to claim 6, wherein: the humectant B comprises one or more of 1, 3-propylene glycol and betaine.
8. The essence milk containing the composition is characterized by being prepared from the following raw materials in percentage by mass: 10-13% of humectant C, 2-6% of emollient, 1.0-1.5% of thickener C, 0-0.6% of antioxidant, 0.1-0.5% of preservative, 0.1-0.3% of skin conditioner, 9-12% of composition and water to 100%; the composition used was the composition described in any of examples 1 to 5.
9. The essence milk containing the composition according to claim 8, characterized in that: the humectant C comprises one or more of propylene glycol, glycerol and betaine.
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| CN116725935A (en) * | 2023-07-27 | 2023-09-12 | 广州市精锐生物研究有限公司 | Essence composition with whitening, anti-allergy and anti-wrinkle functions, and preparation method and application thereof |
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| CN114983909B (en) | 2024-01-26 |
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