CN114885894A

CN114885894A - Poultry raising method without resistance in whole process

Info

Publication number: CN114885894A
Application number: CN202210503350.4A
Authority: CN
Inventors: 余恒林
Original assignee: Individual
Current assignee: Individual
Priority date: 2022-05-10
Filing date: 2022-05-10
Publication date: 2022-08-12

Abstract

The application provides a whole-course nonreactive feeding method for poultry, and relates to the technical field of animal breeding. It comprises adding disinfectant, nutritional feed additive and non-nutritional feed additive into feed or drinking water during feeding process, wherein the disinfectant, nutritional feed additive and non-nutritional feed additive do not contain antibiotics; the disinfectant comprises a decamethyl ammonium bromide solution; the nutritional additives comprise liquid supplementing salt and compound vitamins; the non-nutritive feed additive comprises an immunopotentiator, an acidifier and a probiotic. The method has the advantages that the method can be used in a coordinated manner, animal immunity is improved while animal healthy growth environment is maintained, and animal rapid growth is promoted, so that production efficiency is improved.

Description

Poultry raising method without resistance in whole process

Technical Field

The application relates to the technical field of animal breeding, in particular to a poultry raising method without resistance in the whole process.

Background

With the continuous expansion of the industry scale and the industry quantity of the breeding industry in recent years, the integrated and factory-type breeding mode causes that most farms cannot create a normal and good growth environment for livestock and poultry, and the existence of various bacterial pathogens causes livestock and poultry diseases to show a high-incidence trend. In order to improve the survival rate of livestock and poultry, the use of antibiotics is an inevitable trend. At present, the administration routes of antibiotics mainly comprise three forms, namely injection, drinking water addition and feed addition, and a large amount of data analysis shows that the prevention and treatment effect of the antibiotics supplied in the form of drinking water is optimal, but the mode also increases the poisoning probability of poultry and causes extremely adverse effect on the economic benefit of farmers.

In addition, as the antibiotic drug also has drug residues and the risk of improving the tolerance of pathogenic bacteria and the like which are difficult to reverse, the antibiotic drug resistance is one of the common challenges facing human beings in the 21 st century, and Antibiotic Resistance Genes (ARGs) can be spread in a horizontal transfer mode, so that the threats to the health and environmental safety of the human bodies are increased, and the more scientific and sustainable livestock breeding mode cannot be explored.

Disclosure of Invention

The application aims to provide a poultry raising method without resistance in the whole process, and the method has the characteristics of simple process, environmental protection, economy and applicability.

The technical problem to be solved by the application is solved by adopting the following technical scheme.

The embodiment of the application provides a poultry raising method without resistance in the whole process, which comprises the following steps: adding disinfectant, nutritional feed additive and non-nutritional feed additive containing no antibiotics into feed or drinking water during feeding process; the disinfectant comprises a decamethyl ammonium bromide solution; the nutritional additive comprises liquid supplementing salt and compound vitamins; the non-nutritive feed additive comprises an immunopotentiator, an acidifier and a probiotic.

The livestock and poultry breeding industry in China gradually changes from decentralized and individual operation into large-scale intensive operation, diseases are easy to spread rapidly along with the increase of the density of livestock and poultry, in order to prevent the phenomenon, a specific disinfection method is required to be provided for different disinfection objects and disinfection environments, and the adopted disinfectant also needs to select and kill pathogenic microorganisms rapidly, has the efficacy of killing or inhibiting most of bacteria and is harmless to people and livestock and poultry. Nutritive feed additives are trace substances added to a compound feed in addition to conventional feeds to supplement and satisfy various nutritional needs of animals or for a particular purpose. The nutritive feed additive is the core of the compound feed, and the quality and the quantity of the nutritive feed additive directly influence the growth, the production and the feed reward of the livestock and poultry. Commonly used nutritional feed additives include: vitamin additives, trace element additives and amino acid additives. Non-nutritive feed additives are not inherent nutrients in feed and can be broadly classified into four categories according to their actions: growth promoter, insect repellent health agent, feed preservative and other additives. The common point of the three is that the production of animals is ensured from different actions. The three components are used coordinately, so that the healthy growth environment of animals is maintained, the autoimmunity of the animals is improved, the production efficiency is improved, the use of antibiotics is avoided, and the purpose of green production is achieved.

The disinfectant selected by the application comprises a decamethylammonium bromide solution added into drinking water, wherein decamethylammonium bromide is a double-chain quaternary ammonium salt disinfectant, has a killing effect on most bacteria, fungi and algae, and also has a certain effect on lipophilic viruses. When the antibacterial agent is in a solution state, quaternary ammonium salt cations can be dissociated and combined with phosphate groups with negative charges in bacterial cytoplasmic membrane phospholipids, the antibacterial effect is achieved at low concentration, and the bactericidal effect is achieved at high concentration. The bromine ions enhance the hydrophilicity and lipophilicity of molecules, can rapidly permeate into a plasma membrane lipid layer and a protein layer, change the permeability of the membrane and achieve the bactericidal effect. The decamethyl ammonium bromide has strong efficacy, is stable to light and heat, has a surface activity function, can enable the medicament to permeate into gaps and cracks, and has no corrosion to metal, plastic, rubber and other substances.

Nutritional feed additives including rehydration salts and multivitamins are used in this application. The rehydration salt belongs to a compound preparation, mainly comprises anhydrous glucose, sodium chloride, potassium chloride and sodium bicarbonate, can supplement sodium, potassium and body fluid, regulate the balance of water and electrolyte, and has the effect of expelling toxins by glucose.

Vitamins are a kind of trace organic substances which are necessary to be obtained from food for human and animals to maintain normal physiological functions, play an important role in the processes of growth, metabolism and development of animal organisms, supplement compound vitamins for poultry is helpful to ensure the necessary vitamin intake of the poultry and avoid vitamin deficiency.

Non-nutritive additives including immunopotentiators, acidifiers and probiotics are employed in the present application.

The immunopotentiator is mainly used for enhancing the anti-tumor effect and anti-infection capability of an organism and correcting immunodeficiency, and the medicine can activate one or more immunocompetent cells, enhance the specific and non-specific immune functions of the organism, recover the low immune functions to be normal, or has the adjuvant effect, enhances the immunogenicity of the antigen combined with the immunopotentiator and accelerates the induction of immune response reaction; or substitute for lacking immunological active components in vivo to generate immunological substitution effect; or has bidirectional regulating effect on the immune function of the organism, so that the over-high or over-low immune function tends to be normal.

The acidifying agent can be combined with mineral elements to form a complex which is easy to absorb and utilize, such as citric acid and fumaric acid, which can form a complex with high biological value with Ca, Zn, Fe, P, Mg, etc., and promote the absorption and retention of these elements in vivo. The acidifier can not only form an absorbable complex with the mineral, but also prevent the mineral from forming insoluble salt which is not easy to absorb in an alkaline environment, thereby playing a role in promoting the absorption of the mineral; meanwhile, in an acidic environment, the absorption of vitamins (such as VA and VD) is facilitated, the reduction of the acidic condition of the gastrointestinal tract is beneficial to the improvement of the activity of enzyme, the propagation and growth of lactic acid bacteria can be promoted, harmful microorganisms such as escherichia coli and the like are inhibited, and the microbial system in the gastrointestinal tract is further changed; the acidifier can also improve palatability of feed, increase feed intake of animals, and is helpful for resisting stress and enhancing immunity.

Probiotics can be divided into single strains and complex strains, the latter being commonly used in production. Different probiotics can play different roles, and currently, the probiotics approved by the state comprise bacillus, lactobacillus, streptococcus faecalis, saccharomycetes and the like. The bacillus has higher activity of protease, lipase and amylase, so that the growth speed and the feed conversion rate of livestock and poultry can be obviously improved; the organic acid, special enzyme system, acidomycin and other substances generated by the fermentation of the lactobacillus have special physiological functions, can stimulate the development of tissues and have effects on the nutritional state, physiological function, immune response, stress response and the like of organisms; the faecal streptococcus can prevent and treat intestinal flora disorder of animals, has the effects of decomposing protein into small peptides, synthesizing B vitamins and the like, and can also promote the immune response of cultured animals, improve the antibody level and enhance the activity of macrophages.

The probiotics are added into the feed for poultry, so that the microecological balance of the digestive tract can be adjusted, nutrient substances contained in the feed can be directly absorbed by organisms as nutrient components, the immunity of the organisms is enhanced, and the substances such as organic acids, bacteriocins and the like generated by the probiotics can competitively reject or inhibit the growth, survival and propagation of putrefying bacteria such as escherichia coli and the like in intestinal tracts, so that the quantity of pathogenic bacteria and ammonia discharged out of the bodies along with excrement is reduced, the breeding environment of livestock and poultry is improved, and the quality of animal products is improved.

During the whole feeding process, microorganisms in the environment can easily enter the body along with the feeding action of the poultry, and from the digestive tract, the poultry have three immune barriers which can resist the invasion of harmful microorganisms: 1. intestinal mucosa, 2 intestinal epithelial cells, 3 lymphoid immune cells, thus ensuring the integrity of the three major barriers is important for maintaining the health of poultry.

The application also starts from the direction of preventing diseases: firstly, the provided probiotics can protect the health of intestinal tracts and promote the increase of the height/crypt depth value of the intestinal tracts, so that the aim of preventing germs from invading the intestinal tracts is fulfilled, and a first key is protected; secondly, vitamin A and vitamin B3 in the provided compound vitamins also have the function of helping mucous membrane repair, have the function of maintaining the health of intestinal epithelial cells and defend the second pass; moreover, the immunopotentiator has the functions of enhancing the phagocytosis of pathogenic bacteria by macrophages and improving the immune function of lymphoid immune cells, and is in the third place of protection. This is the principle of the present application that this feeding method is used to reduce the incidence of disease to a few tenths of a percent.

Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:

the application adopts the decamethyl ammonium bromide solution which can rapidly kill pathogenic microorganisms as a disinfectant, is used for killing most of bacteria in the production environment of poultry, lays a good environmental foundation for the growth of the poultry, and adds nutrient feed additives including liquid supplementing salt and compound vitamins into feed or drinking water. Wherein the liquid supplementing salt can supplement sodium, potassium and body fluid, and regulate balance of water and electrolyte. The multivitamins ensure the necessary vitamin requirements of the poultry. Finally, the immunopotentiator generates a bidirectional regulation effect on the immune function of an organism by combining with a non-nutritive feed additive, so that the over-high or over-low immune function tends to be normal. The probiotics are beneficial to regulating the balance of microbial flora in the gastrointestinal tract of the poultry and promoting digestion and absorption. The acidifying agent coordinates the use of probiotics, promotes the growth of beneficial flora, inhibits the reproduction of harmful flora, and the immunopotentiator coordinates vitamins to ensure the healthy immunoregulation capability of poultry, coordinates the use of the three, can maintain the healthy growth environment of animals, also improves the autoimmunity of animals, promotes the rapid growth of animals, thereby improving the production efficiency, and can coordinate the use of each component to condition the body of poultry under the condition of epidemic diseases.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to specific examples.

The application adopts the decamethyl ammonium bromide solution which can rapidly kill pathogenic microorganisms as a disinfectant, is used for killing most of bacteria in the production environment of poultry, lays a good environmental foundation for the growth of the poultry, and adds nutrient feed additives including liquid supplementing salt and compound vitamins into feed or drinking water. Wherein, the liquid supplementing salt can supplement sodium, potassium and body fluid, regulate the balance of water and electrolyte, and the compound vitamin ensures the vitamin requirement necessary for poultry. Finally, the immunopotentiator generates a bidirectional regulation effect on the immune function of an organism by combining with a non-nutritive feed additive, so that the over-high or over-low immune function tends to be normal. The probiotics are beneficial to regulating the balance of microbial flora in the gastrointestinal tract of the poultry and promoting digestion and absorption. The acidifying agent is used for coordinating probiotics, the growth of beneficial flora is promoted, the propagation of harmful flora is inhibited, the immune reinforcing agent is used for coordinating vitamins to ensure the healthy immune regulation capability of poultry, the acidifying agent, the immune reinforcing agent and the vitamins are used for coordinating, the healthy growth environment of animals can be maintained, the autoimmunity of the animals is improved, the rapid growth of the animals is promoted, the production efficiency is improved, under the condition of epidemic diseases, all components can be used for coordinating, the body of the poultry is conditioned, the method can be used for feeding the poultry without resistance completely, the use opportunity of antibiotics is avoided, and the purpose of green production is achieved.

In some embodiments of the present application, the above-described decamethylammonium bromide solution has an active ingredient content of 10%.

The decamethyl ammonium bromide solution has certain irritation when used for disinfecting drinking water environment, the dosage in the environment is small, and stable houses and appliances are disinfected: 0.015% -0.05% solution; drinking water disinfection: 0.0025 to 0.005 percent of solution. The selection of an active ingredient content of 10% may facilitate formulation by the user.

In some embodiments of the present application, the acidity of the acidifying agent is at a pH of 3.5 to 5.

The poultry acidifier is mainly used for helping to digest part of cellulose, inhibiting the reproduction of pathogenic bacteria such as staphylococcus, streptococcus, escherichia coli and the like, improving the laying rate and the feed reward, and the acidifier with the acidity of 3.5-5 is selected to ensure the content of organic acid, and mainly consists of some organic acids in the range, including single acid and compound organic acid. The organic acid can be oxidized into carbon dioxide and bicarbonate in poultry bodies, harm caused by blood alkalinity can be buffered, the pH value of blood can be maintained, the appropriate range of the pH value can be ensured, and in poultry, respiratory alkalosis of poultry can be caused by heat stress, so that stress caused by summer heat can be avoided or relieved by using the acidifier containing the organic acid.

In some embodiments of the present application, the immunopotentiator component is isoprinosine.

Isoprinosine is an immunomodulatory drug, and in vitro experiments prove that it can enhance the immune response of PHA or antigen, promote the differentiation and proliferation of T lymphocytes, and stimulate the differentiation and antibody production of B lymphocytes by activating TH cells or macrophages. Can be made into feed premix with vitamin C, Astragalus polysaccharides, etc. for improving animal organism immunity; it can be made into specific antiviral medicine by mixing with radix Isatidis, radix astragali, flos Lonicerae, fructus forsythiae, Scutellariae radix, etc. The antiviral effect is better than ribavirin and amantadine, and the immunity enhancing effect is better than polyinosinic, levamisole, thymosin and the like.

In some embodiments of the present application, the nutritional feed additive is specifically used in the following dosage: adding the rehydration salt into drinking water according to the standard of 0.2-0.3 g/L; adding the compound vitamin into drinking water according to the standard of 0.5-1.5 g/L; the mass ratio of the probiotics to the water is 1: 200 to 500.

The dosage is standardized from the lowest use standard to the highest use standard, so that all nutritional feed additives can be guaranteed to be used safely and effectively, and the production is guaranteed to be carried out effectively.

In some embodiments of the present application, the non-nutritive feed additive is specifically used in the following dosage: the mass ratio of isoprinosine to water is 1-2: 10000; the mass ratio of the acidifying agent to water is 1-2: 1000.

the dosage is standardized according to the minimum use standard to the maximum use standard, so that all the non-nutritive feed additives can be ensured to be used safely and effectively, and the production is ensured to be carried out effectively.

In some embodiments of the present application, the specific methods of use of the disinfectant, the nutritive feed additive and the non-nutritive feed additive in the feeding process are as follows:

decamethyl ammonium bromide solution: and (3) for 0-8 weeks, wherein the mass ratio is 1: 2000 is diluted into drinking water, and the weight ratio of the mixture is 1: 1600 is diluted into drinking water, and the weight ratio of the mixture is 1: 1200 diluting into drinking water; the medicine is used once a day for 0-3 days, and is used twice a week after 3 days, and the use time of each time is longer than 8 hours.

Liquid supplementing salt: the time for each use lasts for 2-4 h after 0-10 days, and the device is stopped after 10 days.

Vitamin complex: the method is used for 0-10 days, once a day, 10 days and marketing, twice a month, three days each time, and the use time of each time is 2-4 h.

Acidifying agent: sterilizing a waterline, wherein the mass ratio of the waterline to the waterline is 2: 1000 with water, once per week; when the additive is added into drinking water for use, the weight ratio is 1: 1000 and water.

Isoprinosine: adding the mixture for 0-4 weeks in two times, wherein the mixture is taken once a day, and the use time of each time is four hours; the treatment is carried out after 4 weeks and every half month for three days.

And (3) probiotics: 4 days to 1 month, and mixing the raw materials according to a mass ratio of 1: 200 is diluted into drinking water once a day; 2-3 months, and the weight ratio of the components is 1: 300 is diluted into drinking water and is used for one week every half month; and (3) marketing in 3 months, wherein the mass ratio is 1: 500 is diluted into drinking water, and is used for three days every half month, and the using time of each time is more than 8 h.

Wherein the 1 time is any time point of feeding every day, and the nutritional feed additive and the non-nutritional feed additive are added in combination with drinking water amount every time.

It should be noted that, as used herein, a 10% decamethylammonium bromide solution (Baidu) is used, and probiotics are not used when the decamethylammonium bromide solution is used. Although the content of the decamethyl ammonium bromide solution is extremely low in the actual production process, the decamethyl ammonium bromide solution belongs to a broad-spectrum disinfectant, has the same damage function on the structure of probiotics, and can achieve the expected effect of using the probiotics by separately using the decamethyl ammonium bromide solution and the probiotics. In addition, the Baidu was killed within 3 days after seedling entry as 1: 2000 is diluted into drinking water to feed the chicks, in order to reestablish a microbial system in digestive tracts of the chicks, the effect that the hundred poisons are diluted in the proportion and used for drinking water is achieved for the first time, pathogenic bacteria contained in the chicks and coming from female parents are eliminated, and therefore preparation is made for later establishing a new microbial ecosystem by using the probiotic coordinated acidifier.

The specific use conditions of the disinfectant, the nutritional feed additive and the non-nutritional feed additive in different growth stages of the poultry are reasonably planned by combining the effective conditions of the long-term production practice of the application, and the production can be ensured to achieve the expected green and efficient production according to the production flow.

In some embodiments of the present application, the probiotic bacteria and the acidulant are used in combination by pouring the acidulant first and then mixing the probiotic bacteria.

The application method comprises adding acidifying agent and probiotics during feeding. The range of the suitable acidity of the probiotics can be achieved by adjusting the pH value of the gastrointestinal tract by using an acidifier, so that the optimal using effect can be achieved by combining the acidifier and the acidifier, the proliferation of beneficial bacteria in the gastrointestinal tract of the poultry is promoted, the propagation of harmful bacteria is inhibited, the healthy digestion of the poultry is further ensured, the absorption of nutrition is promoted, and the production efficiency is improved.

In some embodiments of the present application, after 4 weeks of age, bile acid is added to the feed, and the mass ratio of the bile acid to the feed is 200g to 400 g: 1000 kg.

When poultry eat the feed, the digestive system is gradually improved, the growth speed is high, the demand for the feed is increased, and the bile acid molecules contain hydrophilic hydroxyl and carboxyl, hydrophobic methyl and hydrocarbon nucleus. Meanwhile, the space coordination of hydroxyl and carboxyl is all alpha type, so the main configuration of the bile acid has two sides of hydrophile and hydrophobe, which makes the molecule have the characteristics of interface active molecule, and can reduce the surface tension between oil and water phases and promote the lipid emulsification. Bile acid helps to emulsify fat, enhance lipolysis of pancreas, and promote lipid absorption by intestinal tract by forming mixed micelles to improve lipid solubility. The application adopts the technical scheme that bile acid is added into feed, and the mass ratio of the bile acid to the feed is 200-400 g: 1000kg, and the use amount is limited by selecting the range of the minimum use and applicable utility range, so that the safe production is ensured.

In some embodiments of the present application, the bile acid is used by being added to the feed at all times.

The bile acid is added into the feed all the time, so as to play the role of the bile acid and promote the digestion and absorption of the poultry on the feed, thereby reducing the load of the liver, ensuring the detoxification of the liver, flushing lipid scales such as denatured fat, drug toxin, mycotoxin, heavy metal and the like deposited in the liver out of the liver together, discharging the lipid scales into an intestinal canal through the circulation of the liver and intestine and discharging the lipid scales together with excrement to maintain the health of the poultry.

In addition, in some embodiments of the application, fennel is further added into the feed, and the fennel also has the effects of tonifying spleen, stimulating appetite, warming intestines, removing fish and botulism in Rihua herbal, so that when the fennel is applied to the poultry raising process, the fennel has the effect of discharging exotoxin and has the effect of protecting liver and gallbladder together with bile acid.

The features and properties of the present application are described in further detail below with reference to examples.

Example 1

Selecting healthy and qualified chicks to enter a factory (feeding), strictly disinfecting a brooding room for three times before feeding the chicks, and alternately disinfecting with different disinfection solutions every time at an interval of seventy-two hours. After the sterilization is finished, the brooding room is preheated to the required temperature, and whether the brooding room sealing meets the requirements or not is checked, and all equipment conditions such as no harmful wind, normal use of a waterline stockline and the like exist.

Preparing feed water one hour before the chicks come back, adding liquid supplementing salt into the water, adding the liquid supplementing salt according to the standard of 0.2g/L, and disinfecting the water and supplementing various vitamins and immunopotentiators by using a disinfectant (Baidu, with the active ingredient content of 10%) containing decamethylbromide solution every day in three days before the chicks come back. The vitamin complex is added into drinking water according to the standard of 0.5 g/L.

The method comprises the following steps of performing vaccination from the fourth day, performing vaccination once every four days, performing drinking water disinfection on chickens and thoroughly cleaning and disinfecting the whole field after forty-eight hours after each vaccination, and in addition, performing probiotic bacteria once a day, and adding a probiotic bacteria synergist (acidifier) for coordinated use when using the probiotic bacteria.

The compound vitamin is used once every half month from the end of the fourth week, the immunopotentiator (isoprinosine) is used once every half month, the probiotics is used once every half month, and the rest is unchanged every week. And at the fourth week, the crushed chicken feed produced by a feed factory is fed into the feed self-batching instead of all additives (such as mildew removal agents, insect repellents and the like) by the feed self-batching, and the quality and flavor of chicken are changed by completely utilizing the five cereals and adding natural seasonings.

Three days of multivitamins, probiotics and immunopotentiators are used every half and a half from the eighth week until marketing.

The environment for controlling the chicken raising must be strictly controlled in the whole raising process. The concrete using methods of the decamethonium bromide solution, the rehydration salt, the multivitamins, the probiotics, the immunopotentiator and the acidifier are as follows in the whole breeding process from feeding to slaughtering:

baidusha (10% decamethylammonium bromide solution): the drinking water is diluted by two thousand times of the water consumption in the first three days, each time is more than eight hours, two hundred-killing reactions (one hundred-killing reaction is used for each disinfection) are carried out every week after three days until the chickens are out of the house, the chickens are fed for eight weeks and then diluted by 1600 times, and the chickens are diluted by 1200 times after 12 weeks.

Liquid supplementing salt: one kilogram of water is added into the feed every 20 grams once a day in the first week of seedling feeding, the feed can be properly prolonged to 10 days according to the condition, the drinking time is not less than four hours every time, and the feed is guaranteed to be finished every time within 2-4 hours.

Vitamin complex: the time from the seedling feeding to the tenth day is not less than four hours every day, and the time is twice a month every three days every ten days later, so that the complete drinking in 2-4 hours every time is ensured.

And (3) probiotics: the time of each time is not less than eight hours every day from four days of seedling feeding, probiotics are used in coordination with the acidifier, and the acidifier is added according to one thousandth of water consumption. Note that: when the probiotics and the acidifier are used coordinately, the acidifier is poured into the acidifier and stirred uniformly, then the probiotics are poured into the acidifier and stirred uniformly, the acidifier is continuously used for one month from the fourth day for the first time according to 200 times of dilution (the probiotics using amount is calculated according to the water using amount of the whole day), the acidifier is diluted for one week every half a month from the second month according to 300 times, and the acidifier is diluted for one time every half month from the third month every three days according to 500 times.

Acidifying agent: the waterline is disinfected once a week and soaked in the waterline in a ratio of two thousandths of a night, and the waterline is discharged outdoors in the next day and is flushed by clear water for normal use.

Isoprinosine (immunopotentiator): after seedlings are fed, the water is continuously used for four weeks once a day, 10 g of water is added into every hundred kilograms of water, and the water is added twice after drinking each time because the isoprinosine aqueous solution is unstable. After four weeks, the medicine is used for three days every half month.

Bile acid: the additive is added into the self-batching material from the beginning, and 200-400 g is added into each ton of the self-batching material.

First, first four weeks old: the first three days are freely drunk by using Baidu water (the decamethylammonium bromide solution is used once a day, more than four hours each time and less than twelve hours), the first ten days are once the compound vitamin and the fluid infusion salt once a day, the fluid infusion salt is stopped after ten days, and the compound vitamin is used for three days to four weeks every week.

It should be noted that: baidu killing of newly-hatched chicks was performed according to the following ratio of 1: diluting by 2000 times, and adding 1: diluted by 1600 times, and the weight of the big chickens aged for more than 8 weeks is 1: 1200-fold dilution, 20 g of Baidu per bottle cap, 10% content, attention: some are only 16 g or 16 ml, and the dosage of the bottle cap needs to be corrected when the bottle cap is used every time, otherwise, the effect is poor. If the drinking water concentration is too high, the larynx or the oral cavity is easy to be damaged, and fester, red swelling and inflammation are caused, so that the medicine concentration must be strictly controlled when the medicine is used.

Three days later probiotics were administered once a day to the fourth week. The water is alternately drunk and the waterline is cleaned once a week by using the Baiduexin and the Securin (the Securin is diluted by 1000 times for a long time or the compound feed acidifier is added in the feed for a medium and long time). Isoprinosine is continuously used for four weeks once a day, and the isoprinine is used coordinately every time when the vaccine is prepared.

Two, four to eight weeks old:

the probiotic bacteria, vitamins and isoprinosine (three are used alternately) are used for one week every fifteen days, and the Baidujing (Baidujing is diluted by 1: 1600 times for drinking water) and the Cefacai are fed once every week. The Baidusha and the Saikai can be alternately used and the waterline is cleaned at the same time, probiotics are forbidden when the Baidusha is used, and the Baidusha and other disinfection medicines are not used one day before and after the vaccine is made. The racel is added to drinking water continuously for 12 hours, preferably 24 hours, with free access to water.

After age of three or eight weeks

Three days daily probiotics were mixed with vitamins, isoprinosine (two were also used alternately weekly), and warfarin (1200 fold dilutions of warfarin) and saxabexatin were fed alternately weekly and washed together with the waterline. The chicken house and the chicken belt body are disinfected twice a week from the time of feeding the chicks and are cleaned comprehensively and sanitarily.

And fourthly, preparing traditional Chinese medicines when the field frequently causes bacterial diseases, and taking the medicines according to the regulations.

Fifthly, when the feed is changed from the preparation of the feed (after brooding for one month, 4 weeks old), bile acid is added into the feed to protect the liver and the gallbladder, and 200g of bile acid is mixed with each ton of the feed.

The formula of the self-prepared material is as follows (the following components are expressed by weight percent):

64% of corn, 3% of bran, 14% of bean pulp, 2% of alfalfa, 2.2% of calcium hydrophosphate, 0.8% of calcium carbonate, 7% of peanut cake and 7% of broad bean.

It should be noted that the self-formula of the present application does not contain any mildew-removing agents or anthelmintics.

The obtained formula comprises the following nutritional ingredients (100g of self-prepared materials): 12.4MJ/kg of metabolizable energy, 18.5g of crude protein, 0.88g of calcium, 0.44g of phosphorus, 0.74g of methionine and cystine, 0.17g of tryptophan, 0.90g of arginine and 0.90g of lysine.

In addition, flavoring agents and bile acids (as 100g self-prepared) were added to the feed:

0.4g of fennel, 1g of dried orange peel, 5g of soybean lecithin, 0.2g of monosodium glutamate, 0.3g of salt and 0.02g of bile acid.

After the antibiotic-free breeding process is applied, the growth speed of ecological chickens is obviously improved, the feed meat ratio is reduced, the weight of 30-day-old black-Yao chickens in the past common breeding process is 500g, the weight can reach 600g to 750g at present, and the feed meat ratio in the past one month is 1.2-1.3: 1, and the current feed-meat ratio is 1.1-1.2: 1, and the weight can reach 1kg in forty-five days, which is obviously higher than the weight of the common breeding before.

In addition, compare the process of raising that has used the antibiotic, this application obviously reduced the cost: for example, when the starter is used, one thousand chickens are used once, at least one bag (100g, 25% content) of amoxicillin (antibiotic) is needed, the market price of one bag of amoxicillin is about 20 yuan, the antibiotic generally needs to be used for 4-5 days, and the starter cost is calculated to be about 100 yuan. This application uses the disinfection of Baidu to kill (10% decamethyl ammonium bromide solution) drinking water to solve because the disease of mother source vertical propagation, and a bottle 500mL market price is about 20 yuan, once only with 3 ~ 5mL, uses three days, and the opening medicine cost is only about 4 ~ 6 jianchuan.

Example 2

This example is substantially the same as example 1, except that: the concrete using methods of the decamethonium bromide solution, the rehydration salt, the compound vitamin, the probiotics, the immunopotentiator, the acidifier and the isoprinosine in the whole breeding process from the seedling feeding to the slaughtering are as follows:

adding rehydration salt into drinking water according to the standard of 0.25 g/L; adding the compound vitamin into the drinking water according to the standard of 1 g/L; the mass ratio of isoprinosine to water is 1.5: 10000.

when the feed is changed from the preparation of the feed (after brooding for one month, 4 weeks old), bile acid is added into the feed to protect the liver and the gallbladder, and 300 g of bile acid is mixed with each ton of the feed all day.

Example 3

adding rehydration salt into drinking water according to the standard of 0.3 g/L; adding the compound vitamin into drinking water according to the standard of 1.5 g/L; the mass ratio of isoprinosine to water is 2: 10000.

when the feed is changed from the preparation of the feed (after brooding for one month, 4 weeks old), bile acid is added into the feed to protect the liver and the gallbladder, and 400g of bile acid is mixed with each ton of the feed all day.

In summary, the present application proposes a method for raising poultry with no resistance during the whole course, which comprises adding a disinfectant, a nutritive feed additive and a non-nutritive feed additive to the feed or drinking water during the raising process, wherein the disinfectant, the nutritive feed additive and the non-nutritive feed additive do not contain antibiotics; the disinfectant comprises a decamethyl ammonium bromide solution; the nutritional additives comprise liquid supplementing salt and compound vitamins; the non-nutritive feed additive comprises an immunopotentiator, an acidifier and a probiotic. The method can realize the raising of poultry without resistance completely, further stop the use opportunity of antibiotics and achieve the aim of green production.

The embodiments described above are some, but not all embodiments of the present application. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Claims

1. A method for raising poultry without resistance in the whole process is characterized by comprising the following steps: adding a disinfectant, a nutritive feed additive and a non-nutritive feed additive to feed or drinking water during the feeding process, wherein the disinfectant, the nutritive feed additive and the non-nutritive feed additive do not contain antibiotics; the disinfectant comprises a solution of decamethylammonium bromide; the nutritional additives comprise rehydration salt and vitamin complex; the non-nutritive feed additive includes an immunopotentiator, an acidifier, and a probiotic.

2. The method for raising poultry with global antibiotic-free activity as claimed in claim 1, wherein the solution of decamethyl ammonium bromide has an active ingredient of 10%.

3. The poultry raising method without whole antibiotic according to claim 2, wherein the acidifier has an acidity pH of 3.5 to 5.

4. The method for raising poultry with global nonresistance according to claim 3, wherein the immunopotentiator is isoprinosine.

5. The method for raising poultry with global antibiotic-free activity as claimed in claim 4, wherein the nutritional feed supplement is used in the following specific dosage amounts:

adding the rehydration salt into the drinking water according to the standard of 0.2-0.3 g/L;

the multivitamins are added into drinking water according to the standard of 0.5-1.5 g/L.

6. The method for raising poultry with global antibiotic-free activity as claimed in claim 5, wherein the non-nutritive feed additive is used in the following specific dosage:

the mass ratio of isoprinosine to water is 1-2: 10000;

the mass ratio of the acidifying agent to water is (1-2): 1000, parts by weight;

the mass ratio of the probiotics to the water is 1: 200 to 500.

7. The method for raising poultry with total antibiotic resistance as claimed in claim 6, wherein the specific application methods of the disinfectant, the nutritive feed additive and the non-nutritive feed additive in the raising process are as follows:

decamethyl ammonium bromide solution: and (3) for 0-8 weeks, wherein the mass ratio is 1: 2000 is diluted into drinking water, and the weight ratio of the mixture is 1: 1600 is diluted into drinking water, and the weight ratio of the mixture is 1: 1200 diluting into drinking water; the medicine is used once a day for 0-3 days, and is used twice a week after 3 days, and the use time of each time is longer than 8 hours;

liquid supplementing salt: 0-10 days, the time for each use is 2-4 hours, and the product is not used after 10 days;

vitamin complex: 0-10 days, once a day, 10 days to slaughter, twice a month, three days each time, and 2-4 h each time;

acidifying agent: sterilizing a waterline, wherein the mass ratio of the waterline to the waterline is 2: 1000 with water, once per week; when the additive is added into drinking water for use, the weight ratio is 1: 1000 and water dilution;

isoprinosine: adding the mixture in two times every day for four hours in 0-4 weeks; the treatment is carried out after 4 weeks, once every half month and continuously used for three days each time;

and (3) probiotics: 4 days to 1 month, and mixing the raw materials according to a mass ratio of 1: 200 is diluted into drinking water once a day; 2-3 months, and the weight ratio of the components is 1: 300 is diluted into drinking water and is used for one week every half month; and (3) marketing in 3 months, wherein the mass ratio is 1: 500 is diluted into drinking water, and is used for three days every half month, and the time of each use is more than 8 h.

8. The method for raising poultry with total antibiotic resistance as claimed in claim 7, wherein the probiotics and the acidifier are used in combination by pouring the acidifier and then the probiotics.

9. The method for raising poultry with no resistance in the whole course according to claim 8, wherein bile acid is added to the feed after 4 weeks of age, and the mass ratio of the bile acid to the feed is 200 g-400 g: 1000 kg.

10. The method for raising poultry with global nonresistance according to claim 9, wherein the bile acid is used by being added to the feed at all times.