CN114832140A - 一种医用皮肤修复敷料配方 - Google Patents
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Abstract
本发明提供一种医用皮肤修复敷料配方，涉及皮肤修复敷料技术领域。该医用皮肤修复敷料配方，包括以下重量百分比的原料组成：甘油0.1‑2％、蛇床0.5‑1％、苦参0.5‑1.5％、百部0.5‑1％、重组胶原蛋白10‑15％和余量纯化水组成。本发明在制造的过程中添加蛇床、苦参和百部，其中，蛇床具有杀虫止痒、治皮肤湿疹功效，苦参具有清热利湿、抗菌消炎功效，百部具有杀虫、止痒功效，因此，皮肤修复敷料在对皮肤进行修复的同时还能对皮肤进行杀菌消毒，避免细菌对皮肤造成损伤，有利于皮肤的保护。
Description
技术领域
本发明涉及医用皮肤修复敷料技术领域，具体为一种医用皮肤修复敷料配方。
背景技术
皮肤是人体最大的器官，皮肤具有两个方面的屏障作用：一方面防止体内水分、电解质、其他物质丢失；另一方面阻止外界有害物质的侵入，保持人体内环境的稳定，在生理上起着重要的保护功能。随着年龄的增长，皮肤受紫外线及空气中的污染物的作用，容易缺乏营养，进而使皮肤失水，破坏皮肤的角蛋白，造成皮肤粗糙，失去弹性。为了营养皮肤，防止皮肤粗糙，人们对皮肤修复敷料进行了探索，研究出了多种对皮肤保湿及营养的修复敷料。
现有的皮肤修复敷料在制造时主要对皮肤进行修复，但是皮肤出现伤口时，容易感染细菌，从而给皮肤带来进一步的损伤。
发明内容
(一)解决的技术问题
针对现有技术的不足，本发明提供了一种医用皮肤修复敷料配方，解决了皮肤出现伤口时，容易感染细菌，从而给皮肤带来进一步的损伤的问题。
(二)技术方案
为实现以上目的，本发明通过以下技术方案予以实现：一种医用皮肤修复敷料配方，包括以下重量百分比的原料组成：甘油0.1-2％、蛇床0.5-1％、苦参0.5-1.5％、百部0.5-1％、重组胶原蛋白10-15％和余量纯化水组成。
一种医用皮肤修复敷料的制备方法，包括以下制备步骤：
步骤一：称取配方量的蛇床、苦参和百部进行提取液操作，并将提取的液体放入无菌瓶内保存；
步骤二：称取配方量的甘油、重组胶原蛋白和纯化水，并将甘油、重组胶原蛋白和纯化水放入容器中搅拌混合；
步骤三：将步骤一中提取的液体加入甘油、重组胶原蛋白和纯化水混合溶液中并搅拌均匀，并放置在无菌的环境中静置20-30分钟，进而得到皮肤医用修复敷料；
步骤四：将敷贴基材进行杀菌消毒，并在无菌的环境中将敷贴基材和步骤三中的皮肤医用修复敷料放入铝箔袋内
优选的，所述步骤四中的敷贴基材为无纺布，并且敷贴基材的形状为方形和圆形其中的任意一种
(三)有益效果
本发明提供了一种医用皮肤修复敷料配方。具备以下有益效果：
本发明，在制造的过程中添加蛇床、苦参和百部，其中，蛇床具有杀虫止痒、治皮肤湿疹功效，苦参具有清热利湿、抗菌消炎功效，百部具有杀虫、止痒功效，因此，皮肤修复敷料在对皮肤进行修复的同时还能对皮肤进行杀菌消毒，避免细菌对皮肤造成损伤，有利于皮肤的保护。
具体实施方式
下面将对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
实施例一：
本发明实施例提供一种医用皮肤修复敷料配方，包括以下重量百分比的原料组成：甘油0.8％、蛇床0.5％、苦参0.5％、百部0.5％、重组胶原蛋白10％和余量纯化水组成。
其中，甘油具有保湿、滋润的作用，还可以在皮肤上形成一种保护膜，蛇床具有杀虫止痒、治皮肤湿疹功效，苦参具有清热利湿、抗菌消炎功效，百部具有杀虫、止痒功效，重组胶原蛋白作为活性物质扩散到皮肤的深层，其含有的酪氨酸与皮肤中的酪氨酸竞争，而与酪氨酸酶的催化中心结合，从而抑制黑色素的产生，使皮肤中的胶原蛋白活性增强，保持了角质层水分以及纤维结构的完整性，促进皮肤组织的新陈代谢，保护细胞不受病原菌的侵害，加快恢复皮肤屏障、增强免疫力等作用。
一种医用皮肤修复敷料的制备方法，包括以下制备步骤：
步骤一：称取配方量的蛇床、苦参和百部进行提取液操作，并将提取的液体放入无菌瓶内保存；
步骤二：称取配方量的甘油、重组胶原蛋白和纯化水，并将甘油、重组胶原蛋白和纯化水放入容器中搅拌混合；
步骤三：将步骤一中提取的液体加入甘油、重组胶原蛋白和纯化水混合溶液中并搅拌均匀，并放置在无菌的环境中静置30分钟，进而得到皮肤医用修复敷料；
步骤四：将敷贴基材进行杀菌消毒，并在无菌的环境中将敷贴基材和步骤三中的皮肤医用修复敷料放入铝箔袋内。
其中步骤四中的敷贴基材为无纺布，并且敷贴基材的形状为方形和圆形其中的任意一种。
实施例二：
一种医用皮肤修复敷料配方，包括以下重量百分比的原料组成：甘油1％、蛇床0.6％、苦参1％、百部0.7％、重组胶原蛋白13％和余量纯化水组成。
一种医用皮肤修复敷料的制备方法，包括以下制备步骤：
步骤一：称取配方量的蛇床、苦参和百部进行提取液操作，并将提取的液体放入无菌瓶内保存；
步骤二：称取配方量的甘油、重组胶原蛋白和纯化水，并将甘油、重组胶原蛋白和纯化水放入容器中搅拌混合；
步骤三：将步骤一中提取的液体加入甘油、重组胶原蛋白和纯化水混合溶液中并搅拌均匀，并放置在无菌的环境中静置30分钟，进而得到皮肤医用修复敷料；
步骤四：将敷贴基材进行杀菌消毒，并在无菌的环境中将敷贴基材和步骤三中的皮肤医用修复敷料放入铝箔袋内。
其中步骤四中的敷贴基材为无纺布，并且敷贴基材的形状为方形和圆形其中的任意一种。
实施例三：
一种医用皮肤修复敷料配方，包括以下重量百分比的原料组成：甘油2％、蛇床1％、苦参1.5％、百部1％、重组胶原蛋白15％和余量纯化水组成。
一种医用皮肤修复敷料的制备方法，包括以下制备步骤：
步骤一：称取配方量的蛇床、苦参和百部进行提取液操作，并将提取的液体放入无菌瓶内保存；
步骤二：称取配方量的甘油、重组胶原蛋白和纯化水，并将甘油、重组胶原蛋白和纯化水放入容器中搅拌混合；
步骤三：将步骤一中提取的液体加入甘油、重组胶原蛋白和纯化水混合溶液中并搅拌均匀，并放置在无菌的环境中静置30分钟，进而得到皮肤医用修复敷料；
步骤四：将敷贴基材进行杀菌消毒，并在无菌的环境中将敷贴基材和步骤三中的皮肤医用修复敷料放入铝箔袋内。
其中步骤四中的敷贴基材为无纺布，并且敷贴基材的形状为方形和圆形其中的任意一种。
尽管已经示出和描述了本发明的实施例，对于本领域的普通技术人员而言，可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由所附权利要求及其等同物限定。
Claims (3)
1.一种医用皮肤修复敷料配方，其特征在于：包括以下重量百分比的原料组成：甘油0.1-2％、蛇床0.5-1％、苦参0.5-1.5％、百部0.5-1％、重组胶原蛋白10-15％和余量纯化水组成。
2.根据权利要求1所述的一种医用皮肤修复敷料的制备方法，其特征在于：包括以下制备步骤：
步骤一：称取配方量的蛇床、苦参和百部进行提取液操作，并将提取的液体放入无菌瓶内保存；
步骤二：称取配方量的甘油、重组胶原蛋白和纯化水，并将甘油、重组胶原蛋白和纯化水放入容器中搅拌混合；
步骤三：将步骤一中提取的液体加入甘油、重组胶原蛋白和纯化水混合溶液中并搅拌均匀，并放置在无菌的环境中静置20-30分钟，进而得到皮肤医用修复敷料；
步骤四：将敷贴基材进行杀菌消毒，并在无菌的环境中将敷贴基材和步骤三中的皮肤医用修复敷料放入铝箔袋内。
3.根据权利要求1所述的一种医用皮肤修复敷料的制备方法，其特征在于：所述步骤四中的敷贴基材为无纺布，并且敷贴基材的形状为方形和圆形其中的任意一种。
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6027728A (en) * | 1998-08-05 | 2000-02-22 | Yuen; Liu | Herbal skin regeneration composition and method |
| CN106581741A (zh) * | 2016-12-27 | 2017-04-26 | 西安惠普生物科技有限公司 | 一种重组人源胶原蛋白敷料及其制备方法 |
| CN106902381A (zh) * | 2017-03-23 | 2017-06-30 | 陕西慧康生物科技有限责任公司 | 重组人源胶原蛋白原液、敷料以及它们的制备方法 |
| CN108273122A (zh) * | 2018-02-22 | 2018-07-13 | 江苏创铭医疗器械有限公司 | 一种重组胶原蛋白水凝胶创伤敷料及其制备方法和应用 |
| CN109529104A (zh) * | 2019-01-21 | 2019-03-29 | 创復(常州)生物科技有限公司 | 促进细胞增殖迁移的凝胶敷料及其制备方法、使用方法 |
| CN111803624A (zh) * | 2020-07-27 | 2020-10-23 | 陕西医药控股集团生物制品有限公司 | 一种含有转移因子的皮肤抗菌凝胶制剂和制备方法 |
| CN113813439A (zh) * | 2021-11-04 | 2021-12-21 | 湖南愈尔美医疗科技有限公司 | 一种医用酵母重组ⅲ型胶原蛋白敷料的制备方法 |
-
2022
- 2022-05-06 CN CN202210488884.4A patent/CN114832140A/zh active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6027728A (en) * | 1998-08-05 | 2000-02-22 | Yuen; Liu | Herbal skin regeneration composition and method |
| CN106581741A (zh) * | 2016-12-27 | 2017-04-26 | 西安惠普生物科技有限公司 | 一种重组人源胶原蛋白敷料及其制备方法 |
| CN106902381A (zh) * | 2017-03-23 | 2017-06-30 | 陕西慧康生物科技有限责任公司 | 重组人源胶原蛋白原液、敷料以及它们的制备方法 |
| CN108273122A (zh) * | 2018-02-22 | 2018-07-13 | 江苏创铭医疗器械有限公司 | 一种重组胶原蛋白水凝胶创伤敷料及其制备方法和应用 |
| CN109529104A (zh) * | 2019-01-21 | 2019-03-29 | 创復(常州)生物科技有限公司 | 促进细胞增殖迁移的凝胶敷料及其制备方法、使用方法 |
| CN111803624A (zh) * | 2020-07-27 | 2020-10-23 | 陕西医药控股集团生物制品有限公司 | 一种含有转移因子的皮肤抗菌凝胶制剂和制备方法 |
| CN113813439A (zh) * | 2021-11-04 | 2021-12-21 | 湖南愈尔美医疗科技有限公司 | 一种医用酵母重组ⅲ型胶原蛋白敷料的制备方法 |
Non-Patent Citations (1)
| Title |
|---|
| 何越等: "重组胶原蛋白敷料的生物相容性及动物有效性研究", 《中国美容整形外科杂志》 * |
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