CN114786694A - 用于通过基因疗法治疗诸如帕金森病的突触核蛋白病变的病毒颗粒 - Google Patents

用于通过基因疗法治疗诸如帕金森病的突触核蛋白病变的病毒颗粒 Download PDF

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Publication number
CN114786694A
CN114786694A CN202080064577.2A CN202080064577A CN114786694A CN 114786694 A CN114786694 A CN 114786694A CN 202080064577 A CN202080064577 A CN 202080064577A CN 114786694 A CN114786694 A CN 114786694A
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seq
aav
viral particle
promoter
sequence
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Chinese (zh)
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G·冈萨勒斯阿斯桂诺拉杂
J·L·兰齐戈佩雷斯
R·M·林登
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Biomedical Network Research Consortium Center
UCB Biopharma SRL
Applied Medicine Research Foundation
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Biomedical Network Research Consortium Center
UCB Biopharma SRL
Applied Medicine Research Foundation
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Application filed by Biomedical Network Research Consortium Center, UCB Biopharma SRL, Applied Medicine Research Foundation filed Critical Biomedical Network Research Consortium Center
Publication of CN114786694A publication Critical patent/CN114786694A/zh
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CN202080064577.2A 2019-08-12 2020-08-06 用于通过基因疗法治疗诸如帕金森病的突触核蛋白病变的病毒颗粒 Pending CN114786694A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382706.0 2019-08-12
EP19382706 2019-08-12
PCT/EP2020/072087 WO2021028299A1 (en) 2019-08-12 2020-08-06 Viral particles for use in treating synucleinopathies such as parkinson's diseases by gene therapy

Publications (1)

Publication Number Publication Date
CN114786694A true CN114786694A (zh) 2022-07-22

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CN202080064577.2A Pending CN114786694A (zh) 2019-08-12 2020-08-06 用于通过基因疗法治疗诸如帕金森病的突触核蛋白病变的病毒颗粒

Country Status (18)

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US (1) US20220298528A1 (https=)
EP (1) EP4013437A1 (https=)
JP (1) JP2023500011A (https=)
KR (1) KR20220099944A (https=)
CN (1) CN114786694A (https=)
AR (1) AR119609A1 (https=)
AU (1) AU2020328827A1 (https=)
BR (1) BR112022002615A2 (https=)
CA (1) CA3149844A1 (https=)
CL (1) CL2022000292A1 (https=)
CO (1) CO2022001192A2 (https=)
EC (1) ECSP22008949A (https=)
IL (1) IL290357A (https=)
MX (1) MX2022001676A (https=)
PE (1) PE20220601A1 (https=)
PH (1) PH12022550282A1 (https=)
TW (1) TW202120687A (https=)
WO (1) WO2021028299A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118715316A (zh) * 2022-10-08 2024-09-27 凌意(杭州)生物科技有限公司 用于治疗GCase缺乏相关疾病的多核苷酸
CN120866360A (zh) * 2022-04-19 2025-10-31 上海天泽云泰生物医药有限公司 用于治疗神经退行性障碍的重组aav载体

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021015312A2 (pt) 2019-02-04 2021-11-09 Freeline Therapeutics Ltd Polinucleotídeos, partícula viral e composição
EP4192961A2 (en) * 2020-08-06 2023-06-14 Fundacion para la Investigacion Medica Aplicada Viral particles for use in treating tauopathies such as alzheimer's diseases by gene therapy
WO2025063407A1 (ko) * 2023-09-22 2025-03-27 주식회사 스탠드업테라퓨티스 신규한 파킨슨 병 치료제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3292206B8 (en) * 2015-05-07 2022-02-09 Takeda Pharmaceutical Company Limited Glucocerebrosidase gene therapy for parkinson's disease
EP3692075A4 (en) * 2017-10-03 2022-02-09 Prevail Therapeutics, Inc. GENE THERAPIES FOR LYSOSOMAL DISEASES
WO2019068854A1 (en) * 2017-10-06 2019-04-11 Ospedale San Raffaele S.R.L. GENE THERAPY OF NEURODEGENERATIVE DISEASES USING VAA VECTORS

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120866360A (zh) * 2022-04-19 2025-10-31 上海天泽云泰生物医药有限公司 用于治疗神经退行性障碍的重组aav载体
CN118715316A (zh) * 2022-10-08 2024-09-27 凌意(杭州)生物科技有限公司 用于治疗GCase缺乏相关疾病的多核苷酸
CN118715316B (zh) * 2022-10-08 2025-09-19 凌意(杭州)生物科技有限公司 用于治疗GCase缺乏相关疾病的多核苷酸

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PE20220601A1 (es) 2022-04-25
AR119609A1 (es) 2021-12-29
ECSP22008949A (es) 2022-03-31
PH12022550282A1 (en) 2022-11-21
EP4013437A1 (en) 2022-06-22
TW202120687A (zh) 2021-06-01
BR112022002615A2 (pt) 2022-05-03
JP2023500011A (ja) 2023-01-04
AU2020328827A1 (en) 2022-03-03
CL2022000292A1 (es) 2022-10-21
CO2022001192A2 (es) 2022-07-19
WO2021028299A1 (en) 2021-02-18
MX2022001676A (es) 2022-05-03
CA3149844A1 (en) 2021-02-18
US20220298528A1 (en) 2022-09-22
IL290357A (en) 2022-04-01
KR20220099944A (ko) 2022-07-14

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