CN114762698A - Nutrient solution for stimulating collagen repair of female face and equipment method thereof - Google Patents
Nutrient solution for stimulating collagen repair of female face and equipment method thereof Download PDFInfo
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- CN114762698A CN114762698A CN202110668038.6A CN202110668038A CN114762698A CN 114762698 A CN114762698 A CN 114762698A CN 202110668038 A CN202110668038 A CN 202110668038A CN 114762698 A CN114762698 A CN 114762698A
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- 235000015097 nutrients Nutrition 0.000 title claims abstract description 52
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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Abstract
The invention relates to the technical field of subcutaneous repair, in particular to a female face collagen stimulation repair nutrient solution and an equipment method thereof; the feed comprises the following raw materials in parts by weight: 30-40 parts of solvent, 2-8 parts of water-soluble vitamin and 2-6 parts of bird's nest; the solvent, the water-soluble vitamins and the cubilose are used as raw materials, so that the prepared collagen-stimulating repair nutrient solution can stimulate cells, divide the cells, heal skin tissues after the skin tissues meet wounds, stimulate collagen cells per se to grow to achieve the effect of removing wrinkles, repair the skin by a luxurious acupuncture and moxibustion technology, effectively separate broken fibrous tissues, enable subcutaneous tissues to be wounded, stimulate collagen cells per se to grow, and achieve the effect of smoothing wrinkles; the quality of the prepared female face stimulating collagen repairing nutrient solution is effectively improved.
Description
Technical Field
The invention relates to the technical field of subcutaneous repair, in particular to a female face collagen stimulation repair nutrient solution and an equipment method thereof.
Background
Wrinkle removal refers to the removal of small fine lines and wrinkles formed on the skin by external influences through body conditioning or surgery. Removing wrinkles by surgical wrinkle removal, laser radio frequency, etc.
A nutrient injection for repairing neck skin and an application method thereof are disclosed in Chinese patent application No. CN111632070A, and although the beauty injection prepared by the patent document has certain collagen repair performance, the beauty injection has wounds, injection and filling, and the collagen repair effect is poor, so that the performance and the quality of the prepared repair nutrient solution are influenced.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides the nutrient solution for stimulating collagen repair on the face of a female and the equipment and method thereof, the invention takes solvent, water-soluble vitamin and cubilose as raw materials, so that the prepared nutrient solution for stimulating collagen repair can stimulate cells, the cells can divide, skin tissues can heal after encountering wounds, collagen cells of the cells are stimulated to grow to form an elastic fiber net, the growth is carried out for 7-15 days to achieve the effects of plumping, wrinkle removing and improving, the repair effect can reach 80-90% through three times of soft wound, the extracted cubilose extract is used for promoting the division and growth of the cells, the skin is repaired by light luxury needle carving technology, the broken fibrous tissues are effectively separated, the subcutaneous tissues are wounded, the collagen cells of the fibrous tissues of the female are stimulated to grow, the effect of smoothing wrinkles is achieved, the formed minimally invasive surface enables self collagen cells to propagate and grow in a large quantity through separation stimulation, and the sunken part achieves the effect of plumping and smoothing; the quality of the prepared female face stimulating collagen repairing nutrient solution is effectively improved.
In order to achieve the purpose, the invention provides the following technical scheme:
the female face stimulation collagen repair nutrient solution comprises the following raw materials in parts by weight: 30-40 parts of solvent, 2-8 parts of water-soluble vitamin and 2-6 parts of cubilose.
By adopting the technical scheme: the solvent, the water-soluble vitamins and the cubilose are used as raw materials, so that the prepared collagen-stimulating repair nutrient solution can stimulate cells, divide the cells, heal skin tissues after the skin tissues meet wounds, stimulate collagen cells per se to grow to form an elastic fiber net, and grow for 7-15 days to achieve the effects of plumping, removing wrinkles and improving.
The invention is further configured to: the solvent is physiological saline.
By adopting the technical scheme: the invention uses normal saline as solvent, and utilizes hydrodynamic force of liquid to separate flexibly.
The invention is further configured to: the water-soluble vitamin is one of water-soluble vitamin B and water-soluble vitamin C.
By adopting the technical scheme: the invention takes water-soluble vitamins as raw materials, so that the prepared nutrient solution for stimulating collagen repair can promote cell division and accelerate skin healing.
The invention is further configured to: the edible bird's nest is one of golden silk edible bird's nest, white edible bird's nest and blood edible bird's nest.
By adopting the technical scheme: the invention takes the cubilose as a raw material, provides an extracted cubilose extract, stimulates cells and achieves the effect of collagen repair.
The equipment method for stimulating collagen to repair nutrient solution on the face of a female comprises the following steps:
s1, preparing the cubilose extract.
S2, mixing the nidus Collocaliae extract, solvent and water-soluble vitamins uniformly to prepare the collagen-stimulating repair nutrient solution.
And S3, performing soft wound separation on the subcutaneous tissue.
S4, washing the soft wound of the skin by using the collagen-stimulating repair nutrient solution to separate the subcutaneous fascia adhesion cells.
And S5, performing later soft wound on the skin soft wound position.
By adopting the technical scheme: the cubilose extract is used for promoting cell division and growth, the skin is repaired by a light and luxurious needle carving technology, the broken fibrous tissues are effectively separated, the subcutaneous tissues are injured, the collagen cells of the fibrous tissues are stimulated to grow, the effect of smoothing wrinkles is achieved, and the formed minimally invasive surface is stimulated by separation, so that the collagen cells of the minimally invasive surface propagate and grow in a large quantity, and the depressed parts are enabled to achieve the effect of full and smooth.
The invention is further configured to: in the step S1, a bird' S nest extract is prepared, including the steps of:
s101, slicing the cubilose by using a slicer, and freezing at the temperature of-20 ℃.
S102, mashing the frozen cubilose by a mashing machine, homogenizing the crushed cubilose, and adding pre-cooled deionized water in the homogenizing process.
S103, crushing the homogenate by using ultrasonic waves.
S104, taking the supernatant, filtering with an ultrafiltration membrane, diluting the filtrate with a buffer solution, and filtering with the ultrafiltration membrane again;
s105, freezing the ultrafiltration substance, and then freezing and drying by a freezer to obtain the cubilose extract.
By adopting the technical scheme: the method comprises the steps of smashing and crushing the frozen cubilose, filtering the smashed cubilose, extracting a cubilose extract, using the cubilose extract as a raw material, and repairing the cubilose by utilizing stimulated collagen extracted from the cubilose to realize the repairing effect on the skin.
The invention is further configured to: in the step S102, the homogenate is crushed for 20min by an ultrasonic crusher at a rotation speed of 5000 rpm.
By adopting the technical scheme: the invention uses the ultrasonic crusher to crush the homogenate to crush the cubilose cells.
The invention is further configured to: in said step S103, the homogenate is placed in an ice bath during sonication.
By adopting the technical scheme: the invention provides the ultrasonic crushing temperature for ultrasonic treatment by ice bath refrigeration.
The invention is further configured to: in step 104, the buffer is a phosphate buffer.
By adopting the technical scheme: the invention provides a proper pH value through dilution of a buffer solution.
The invention is further configured to: in step S5, the later stage of soft wound of the skin area means that 2-3 months is a growth cycle, and after the first operation, the second and third operations are performed again.
By adopting the technical scheme: according to the invention, through three times of soft wound, the repairing effect can reach 80-90%.
Advantageous effects
Compared with the known public technology, the technical scheme provided by the invention has the following beneficial effects:
the invention takes the solvent, the water-soluble vitamin and the cubilose as raw materials, so that the prepared collagen-stimulating repair nutrient solution can stimulate cells and divide the cells, skin tissues can heal after encountering wounds, collagen cells of the cells are stimulated to grow to form an elastic fiber net, the collagen-stimulating repair nutrient solution can grow for 7-15 days to achieve the effects of plumping, removing wrinkles and improving the effects, the repair effect can reach 80-90% through three times of soft wounds, the extracted cubilose extract is used for promoting the cell division and growth, the skin is repaired by a light luxurious needle carving technology, the broken fibrous tissues are effectively separated, subcutaneous tissues are wounded, the collagen cells of the fibrous tissues of the cells are stimulated to grow, the effect of smoothing wrinkles is achieved, and the formed micro-wound surface is stimulated by separation to propagate and grow the collagen cells of the cells in a large quantity, so that the sunken part can achieve the effects of plumping and recovering.
Drawings
Fig. 1 is a flow chart of an apparatus and method for stimulating collagen repair nutrient solution on female faces.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. It is to be understood that the embodiments described are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The present invention will be further described with reference to the following examples.
Example 1
Referring to fig. 1, the nutritional liquid for stimulating collagen repair on female faces comprises the following raw materials in parts by weight: 30 parts of solvent, 2 parts of water-soluble vitamin and 2 parts of bird's nest.
The solvent is physiological saline.
The water-soluble vitamin is water-soluble vitamin B.
The nidus Collocaliae is golden silk nidus Collocaliae.
The equipment method for stimulating collagen to repair nutrient solution on the face of a female comprises the following steps:
step one, preparing the cubilose extract.
Step two, evenly mixing the cubilose extract, the solvent and the water-soluble vitamin to prepare the collagen-stimulating repair nutrient solution.
And step three, carrying out soft wound separation on the subcutaneous tissues.
And step four, flushing the soft wound of the skin by using the collagen-stimulating repair nutrient solution to separate the subcutaneous fascia adhesion cells.
And step five, performing later soft wound on the skin soft wound position.
The preparation method of the cubilose extract comprises the following steps:
101) slicing nidus Collocaliae with a microtome, and freezing at-20 deg.C.
102) Mashing the frozen cubilose by a mashing machine, homogenizing the crushed cubilose, and adding pre-cooled deionized water in the homogenizing process.
103) And crushing the homogenate by using ultrasonic waves.
104) Taking supernatant, filtering with an ultrafiltration membrane, diluting the filtrate with buffer solution, and filtering with the ultrafiltration membrane again;
105) freezing the ultrafiltered substance, and freeze drying with refrigerator to obtain nidus Collocaliae extract.
Crushing the homogenate for 20min by an ultrasonic crusher under the condition that the rotating speed is 5000 rpm.
During sonication, the homogenate was placed in an ice bath.
The buffer solution is phosphate buffer solution.
The later soft wound of the soft wound part of the skin means that 2 months is a growth cycle, and after the first operation, the second and third operations are carried out again.
Example 2
The nutrient solution for stimulating collagen repair on the female face and the equipment method thereof provided by the embodiment are substantially the same as those of the embodiment 1, and the main differences are as follows: the feed comprises the following raw materials in parts by weight: 40 parts of solvent, 8 parts of water-soluble vitamin and 6 parts of bird's nest;
the water-soluble vitamin is water-soluble vitamin C;
the nidus Collocaliae is white nidus Collocaliae;
3 months is a growth period.
Comparative example 1
The nutrient solution for stimulating collagen repair on the female face and the equipment method thereof provided by the embodiment are substantially the same as those of the embodiment 1, and the main differences are as follows: physiological saline was not used.
Comparative example 2
The nutrient solution for stimulating collagen repair on the female face and the equipment method thereof provided by the embodiment are substantially the same as those of the embodiment 1, and the main differences are as follows: water soluble vitamins are not used.
Comparative example 3
The nutrient solution for stimulating collagen repair on the female face and the equipment method thereof provided by the embodiment are substantially the same as those of the embodiment 1, and the main differences are as follows: no bird's nest extract was used.
Performance testing
The female face stimulation collagen repair nutrient solution prepared in the embodiment 1-2 and the comparative example 1-3 is taken, and the related performance of the prepared female face stimulation collagen repair nutrient solution is detected, wherein the detection method comprises the following steps:
1. respectively detecting the stimulation performance of the collagen repair nutrient solution stimulated by the face of each female according to a detection standard, and recording the obtained test result in a table 1;
TABLE 1 table for testing stimulation effect of collagen repairing nutrient solution
| Test item | Stimulus detection effect |
| Example 1 | Collagen cells grow faster |
| Example 2 | Collagen cells grow faster |
| Comparative example 1 | Collagen cells grow slowly |
| Comparative example 2 | Collagen cells grow slower |
| Comparative example 3 | Collagen cells grow slower |
2. Respectively detecting the stimulation recovery performance of the collagen repair nutrient solution stimulated by the face of each female according to a detection standard, and recording the obtained test result in a table 2;
table 2 table for testing stimulation and recovery performance of collagen repairing nutrient solution
| Test items | Stimulation recovery test effect |
| Example 1 | 91％ |
| Example 2 | 92％ |
| Comparative example 1 | 70％ |
| Comparative example 2 | 50％ |
| Comparative example 3 | 48％ |
By analyzing the relevant data in the table, the nutrient solution for repairing the female face stimulation collagen prepared by the invention not only has good stimulation effect, but also has good de stimulation recovery effect, so that the quality of the prepared nutrient solution for repairing the female face stimulation collagen is effectively improved.
3. Safety:
after the 'ecological skin awakening technology' is adopted to improve the nutritional environment of the skin, the 'point-to-point' deep supplement is carried out, the collagen necessary for the human body is generated, the cells are accelerated to propagate and grow by themselves, the self-repairing regeneration capability of the skin is activated, and self-repairing factors and collagen are generated, so that the skin soft separation technology has no side effect.
4. The treatment course has the effects:
the medicine has effect in 7-15 days, and the best repair period is 50-90 days.
Growth began in 7-15 days.
Activation began in 15-20 days.
The effect appears in 20-28 days.
The self-repairing period is 35-90 days.
The invention takes solvent, water-soluble vitamin and cubilose as raw materials, so that the prepared collagen-stimulating repair nutrient solution can stimulate cells and divide the cells, skin tissues can heal after encountering wounds, collagen cells of the collagen-stimulating repair nutrient solution stimulate the growth of the collagen cells to form an elastic fiber net, the collagen-stimulating repair nutrient solution can grow for 7-15 days to reach the effects of plumpness, wrinkle removal and improvement, the repair effect can reach 80-90% through three times of soft wounds, the extracted cubilose extract can promote the cell division and growth, the skin is repaired by a slight luxury needle carving technology, the broken fibrous tissues are effectively separated, the subcutaneous tissues are wounded, the collagen cells of the fibrous tissues of the collagen cells of the collagen tissues are stimulated to grow, the effect of smoothing wrinkles is achieved, and the formed micro wound surface is stimulated to propagate and grow the collagen cells of the collagen tissues of the collagen of the, the depressed part can achieve the effect of plump and smooth, so that the quality of the prepared nutrient solution for restoring the female face by stimulating collagen is effectively improved.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the corresponding technical solutions.
Claims (10)
1. The female face stimulation collagen repair nutrient solution is characterized by comprising the following raw materials in parts by weight: 30-40 parts of solvent, 2-8 parts of water-soluble vitamin and 2-6 parts of bird's nest.
2. The female facial stimulation collagen repair nutrient solution according to claim 1, wherein said solvent is physiological saline.
3. The nutrient solution for stimulating collagen repair on the female face according to claim 1, wherein the water-soluble vitamin is one of water-soluble vitamin B and water-soluble vitamin C.
4. The female facial stimulated collagen repair nutrient solution as claimed in claim 1, wherein the bird's nest is one of swiftlet nest, white bird's nest, blood bird's nest.
5. An apparatus and method for female facial stimulation collagen repair nutrient solution, characterized in that the female facial stimulation collagen repair nutrient solution according to any one of claims 1 to 4 is used, comprising the following steps:
s1, preparing the cubilose extract;
s2, uniformly mixing the cubilose extract, the solvent and the water-soluble vitamins to prepare the collagen-stimulating repair nutrient solution;
s3, carrying out soft wound separation on the subcutaneous tissues;
s4, washing the soft wound of the skin by using the collagen-stimulating repair nutrient solution to separate the adhesion cells of the subcutaneous fascia layer;
and S5, performing later soft wound on the skin soft wound position.
6. The apparatus method for female facial stimulation collagen repair nutrient solution according to claim 3, wherein in said step S1, preparing the nidus Collocaliae extract comprises the following steps:
s101, slicing the cubilose by using a slicing machine, and freezing at the temperature of-20 ℃;
s102, mashing the frozen cubilose by a mashing machine, homogenizing the crushed cubilose, and adding pre-cooled deionized water in the homogenizing process;
s103, crushing the homogenate by using ultrasonic waves;
s104, taking the supernatant, filtering with an ultrafiltration membrane, diluting the filtrate with a buffer solution, and filtering with the ultrafiltration membrane again;
s105, freezing the ultrafiltration substance, and then carrying out freeze drying by using a freezer to obtain the cubilose extract.
7. The apparatus method for female facial stimulation collagen repair nutrient solution according to claim 6, wherein in said step S102, the homogenate is crushed for 20min by an ultrasonic crusher at 5000 rpm.
8. The apparatus method for female facial stimulation collagen repair nutrient solution according to claim 6, wherein in said step S103, during the ultrasound process, the homogenate is placed in ice bath.
9. The apparatus method for female facial stimulation collagen repair nutrient solution according to claim 6, wherein in said step 104, said buffer is phosphate buffer.
10. The apparatus method for supplying nutrient solution for female facial stimulation collagen repair according to claim 3, wherein in said step S5, the soft wound at the later stage of the soft wound of skin is a growth cycle of 2-3 months, and after the first operation, the second and third operations are performed again.
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Citations (12)
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