CN114585608B - 虾红素蛋白酶的杂芳族抑制剂 - Google Patents
虾红素蛋白酶的杂芳族抑制剂Info
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- CN114585608B CN114585608B CN202080057197.6A CN202080057197A CN114585608B CN 114585608 B CN114585608 B CN 114585608B CN 202080057197 A CN202080057197 A CN 202080057197A CN 114585608 B CN114585608 B CN 114585608B
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| EP19180240.4 | 2019-06-14 | ||
| EP19180240.4A EP3750878B1 (en) | 2019-06-14 | 2019-06-14 | Heteroaromatic inhibitors of astacin proteinases |
| PCT/EP2020/066352 WO2020249760A1 (en) | 2019-06-14 | 2020-06-12 | Heteroaromatic inhibitors of astacin proteinases |
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| CN114585608A CN114585608A (zh) | 2022-06-03 |
| CN114585608B true CN114585608B (zh) | 2026-03-17 |
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| EP (2) | EP3750878B1 (https=) |
| JP (2) | JP7773377B2 (https=) |
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| BR112021024726A2 (pt) | 2019-06-07 | 2022-01-18 | Elanco Tiergesundheit Ag | Novos derivados bicíclicos |
| EP4244281B1 (en) | 2021-02-26 | 2024-04-03 | Sun Chemical B.V. | Photoinitiator resins with dibenzoylmethane substructure |
| CN113698349B (zh) * | 2021-09-02 | 2023-08-01 | 河南师范大学 | 一种2-(2-苯基-2h-吲唑-3-基)乙酸酯类化合物的水相光催化制备方法 |
| CN114262296B (zh) * | 2021-12-21 | 2023-07-18 | 南京工业大学 | 一种利用微通道反应装置合成咪唑类化合物的方法 |
| WO2023118482A1 (en) | 2021-12-24 | 2023-06-29 | Sun Chemical Corporation | Amine synergists with uv-a absorption |
| CN119101046A (zh) * | 2024-08-30 | 2024-12-10 | 沈阳药科大学 | 3-萘基噻吩类衍生物及其制备方法和应用 |
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| US3624103A (en) * | 1968-05-21 | 1971-11-30 | Abc Ist Biolog Chem Spa | 3-indoleacetohydroxamic acids |
| US4146721A (en) * | 1969-09-12 | 1979-03-27 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pyrazol-4-acetic acid compounds |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021448A (en) * | 1975-10-21 | 1977-05-03 | Sterling Drug Inc. | 2-Substituted-indole-1-lower-alkanecarboxamides |
| KR100432928B1 (ko) * | 2001-04-26 | 2004-05-28 | 주식회사 코오롱 | 신규한 하이드록스아믹산 유도체, 신규한 그의 중간체화합물 및 그들의 제조방법 |
| US20090005344A1 (en) | 2004-11-01 | 2009-01-01 | Nkuada, Llc | Compounds and Methods of Use Thereof |
| DE102005019181A1 (de) * | 2005-04-25 | 2006-10-26 | Novartis Ag | Peptid-Deformylase (PDF) Inhibitoren 1 |
| AU2008252628A1 (en) | 2007-05-18 | 2008-11-27 | Inhibox Ltd. | Bicyclosulfonyl acid (BCSA) compounds and their use as therapeutic agents |
| KR102410199B1 (ko) | 2016-04-18 | 2022-06-17 | 프라운호퍼-게젤샤프트 츄어 푀르더룽 데어 안게반텐 포르슝에.파우. | 새로운 메프린 알파 및 베타 저해제 |
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Patent Citations (2)
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| US3624103A (en) * | 1968-05-21 | 1971-11-30 | Abc Ist Biolog Chem Spa | 3-indoleacetohydroxamic acids |
| US4146721A (en) * | 1969-09-12 | 1979-03-27 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pyrazol-4-acetic acid compounds |
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| Discovery and Refinement of a New Structural Class of Potent Peptide Deformylase Inhibitors;Adrien Boularot,等;Journal of Medicinal Chemistry;20061215;第50卷;第10页摘要及第12页表1 * |
| Synthesis and characterization of two new hydroxamic acids derivatives and their metal complexes. An investigation on the keto/enol, E/Z and hydroxamate/hydroximate forms;Ekrem Adiguzel,等;Journal of Molecular Structure;20160719;第1127卷;第406页Scheme 3 * |
Also Published As
| Publication number | Publication date |
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| EP3750878B1 (en) | 2025-05-14 |
| EP3750878C0 (en) | 2025-05-14 |
| AU2020291114B2 (en) | 2025-12-18 |
| IL288851B2 (en) | 2026-02-01 |
| JP7773377B2 (ja) | 2025-11-19 |
| CN114585608A (zh) | 2022-06-03 |
| KR102930913B1 (ko) | 2026-02-27 |
| EP3750878A1 (en) | 2020-12-16 |
| MX2021015324A (es) | 2022-04-06 |
| MX2025005324A (es) | 2025-06-02 |
| ZA202109419B (en) | 2022-08-31 |
| BR112021024327A2 (pt) | 2022-01-11 |
| JP2025165966A (ja) | 2025-11-05 |
| CA3300715A1 (en) | 2026-03-02 |
| KR20260036022A (ko) | 2026-03-13 |
| US20250388544A1 (en) | 2025-12-25 |
| CA3142992A1 (en) | 2020-12-17 |
| KR20220024216A (ko) | 2022-03-03 |
| IL323353A (en) | 2025-11-01 |
| IL288851B1 (en) | 2025-10-01 |
| JP2022536183A (ja) | 2022-08-12 |
| SG11202112905UA (en) | 2021-12-30 |
| US20230122243A1 (en) | 2023-04-20 |
| IL288851A (en) | 2022-02-01 |
| NZ782669A (en) | 2025-06-27 |
| WO2020249760A1 (en) | 2020-12-17 |
| AU2020291114A1 (en) | 2021-12-23 |
| EP3986868A1 (en) | 2022-04-27 |
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