CN114568589A - Composite vitamin composition and preparation method thereof - Google Patents

Composite vitamin composition and preparation method thereof Download PDF

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Publication number
CN114568589A
CN114568589A CN202210297304.3A CN202210297304A CN114568589A CN 114568589 A CN114568589 A CN 114568589A CN 202210297304 A CN202210297304 A CN 202210297304A CN 114568589 A CN114568589 A CN 114568589A
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vitamin
parts
fish oil
deep sea
sea fish
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邱轶
钱越华
曾美举
刘立强
张选臣
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Guangdong Co Run Biopharmaceutical Co ltd
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Guangdong Co Run Biopharmaceutical Co ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/02—Breeding vertebrates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/22—Compounds of alkali metals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

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Abstract

The invention belongs to the field of feed, and discloses a composite vitamin composition of deep sea fish oil and vitamin ADE for livestock and poultry, which comprises the following components in parts by weight:5.5-10.5 parts of deep sea fish oil; vitamin AD3E7.4-17.8 parts; 20.8-56.3 parts of astragalus extract polysaccharide; 1.8-9.9 parts of hawthorn extract; the vitamin AD3E is vitamin A or vitamin D3Vitamin E; vitamin A and vitamin D3The weight ratio of the vitamin E is as follows: 2.2-6: 0.4-1: 5 to 10. The invention relates to a preparation method of a water-soluble composite vitamin of deep sea fish oil and vitamin ADE for livestock and poultry, which is prepared by compounding highly unsaturated fatty acids (EPA and DHA) in deep sea fish oil with fat-soluble vitamin ADE, astragalus extract polysaccharide and hawthorn extract and carrying out emulsification process treatment. Meanwhile, the invention also provides a preparation method of the composition.

Description

Composite vitamin composition and preparation method thereof
Technical Field
The invention relates to the field of feeds, in particular to a compound vitamin composition and a preparation method thereof.
Background
CN201910864325.7 discloses a health product for promoting the development of head bone and cheek muscle of a cat, which comprises the following components: quinoa, linseed, broccoli, pumpkin seed powder, Chinese yam, almond, lutein, haematococcus pluvialis, chlorella, astragalus polysaccharide, bromelin, ganoderan, fucoidan, ginseng polypeptide, perna canaliculata, oyster peptide, sea cucumber peptide, fish collagen peptide, bovine bone protein peptide, deep sea fish oil DHA, shark chondroitin, lactalbumin, astaxanthin, vitamin A, vitamin B1, vitamin B3, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, zinc gluconate, calcium caseinate, taurine, lysine, methionine, lysine, threonine, leucine, valine, isoleucine, animal-type compound amino acids, chicken meal, cod meal, lactic acid bacteria, hawthorn yeast powder and fruit and vegetable enzyme powder.
The scheme is mainly used for promoting the development of the head bone, the face bone and the cat muscle of the cat.
Each vitamin has specific function to animal body, and can cause vitamin deficiency such as metabolic dysfunction, growth and development pause, and productivity, fertility and immunity resistance reduction, and even death. Vitamins are the basis of all functions of animals and are the key to success and failure of cultivation. Therefore, sufficient vitamins must be supplied to animals, the nutritional requirements of the vitamins of the animals are ensured, and the high yield, high yield and high efficiency of cultivation are promoted.
At present, vitamin ADE additives applied to intensive and large-scale livestock farms in animal husbandry are more single vitamin formula premixes, mainly take the mode of mixing and feeding, only have the vitamin effect, are single in effect, low in digestibility, inconvenient to use, low in production cost and cost performance, and not suitable for the breeding requirements of modernization, intellectualization, convenience and benefit maximization at present.
The compound vitamin feed or the additive is mostly used for raising and researching pets or small batches, and a mature formula for the compound vitamin feed compounded by deep sea fish oil, natural plant extracts and vitamins used for large-scale breeding is not provided in the prior art.
The direction of the important research of the application is as follows: how to improve the digestion condition of the livestock and poultry and the daily gain of the livestock and poultry.
Disclosure of Invention
The invention aims to provide a composite vitamin composition of deep sea fish oil and vitamin ADE for livestock and poultry.
The second object of the present invention is to provide a process for preparing the composition.
In order to realize the aim, the invention provides a compound vitamin composition of deep sea fish oil and vitamin ADE for livestock and poultry, which comprises the following components in parts by weight:
5.5-10.5 parts of deep sea fish oil;
vitamin AD3E7.4-17.8 parts;
20.8-56.3 parts of astragalus extract polysaccharide;
1.8-9.9 parts of hawthorn extract;
the vitamin AD3E is vitamin A or vitamin D3And vitamin E;
vitamin A and vitamin D3Vitamin, vitaminThe weight ratio of E is as follows: 2.2-6: 0.4-1: 5 to 10.
In the above composite vitamin composition of deep sea fish oil for livestock and poultry and vitamin ADE, vitamin A and vitamin D3The weight proportion of the vitamin E is as follows: 3-5: 0.5-0.8: 6-8.
The composite vitamin composition of the deep sea fish oil for livestock and poultry and the vitamin ADE comprises the following components in parts by weight:
7-9 parts of deep sea fish oil;
vitamin AD3E9-14 parts;
25-45 parts of astragalus extract polysaccharide;
3-8 parts of hawthorn extract.
The composite vitamin composition of the deep sea fish oil for livestock and poultry and the vitamin ADE also comprises an emulsifier: 0.5-2.5 parts; 0.5-1.5 parts of antioxidant.
In the vitamin complex composition of deep sea fish oil for livestock and poultry and vitamin ADE, the emulsifier comprises: the weight ratio of tween-80 to co-emulsifier ethanol is 90-96: 4-10;
the antioxidant is one or more of sodium sulfite, sodium metabisulfite or sodium salicylate.
The vitamin complex composition of the deep sea fish oil for livestock and poultry and the vitamin ADE further comprises 963.5-901.5 parts of glucose.
Meanwhile, the invention also discloses a preparation method of the composite vitamin composition of the deep sea fish oil and the vitamin ADE for the livestock and the poultry, which comprises the following steps:
step 1: weighing the deep sea fish oil serving as the raw material according to the prescription amount, adding an appropriate amount of emulsifier, stirring uniformly for emulsification, adding an antioxidant, and stirring uniformly;
step 2: adding the emulsified deep sea fish oil prepared in the step 1 into a certain weight part of glucose, and uniformly premixing;
and step 3: weighing raw material vitamin AD according to prescription amount3E, adding the glucose into a certain weight part of glucose,premixing uniformly;
and 4, step 4: weighing the astragalus extract polysaccharide serving as a raw material in a prescription amount, adding the astragalus extract polysaccharide into glucose in a certain weight part, and uniformly premixing;
and 5: weighing a formula amount of raw material hawthorn extract, adding the raw material hawthorn extract into a certain weight part of glucose, and uniformly premixing;
step 6: and (3) weighing the pre-mixture prepared in the steps (2), (3), (4) and (5), adding the rest glucose according to the proportion of the prescription, uniformly mixing, and subpackaging after qualified detection.
The invention also provides an application of the deep sea fish oil and vitamin ADE compound vitamin for livestock and poultry in livestock and poultry breeding, according to the requirements of livestock and poultry breeding, the compound vitamin can be applied in a mode of mixed drinking water or mixed feed, the mixed feeding addition amount is 2000 g of the product added into each ton of daily ration complete feed, and the product is uniformly mixed and fed; the dosage of the mixed drink is that every 1000 g of the mixed drink is mixed and dissolved in 1000 liters of drinking water for livestock and poultry to drink.
The deep sea fish oil is an unsaturated fatty acid component extracted from deep sea fish animals, contains EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), and during the growth and development of livestock and poultry animals, the unsaturated fatty acid component is beneficial to blood circulation, ensures smooth blood flow and is beneficial to the transportation and utilization of nutrient substances, in addition, the EPA and the DHA in the deep sea fish oil can help the organisms to resist inflammation, has anti-inflammatory activity, relieves the inhibition effect of prostaglandin E2 on immune cells of the organisms, enhances the immune function of the organisms and promotes the health of the livestock and poultry animals. The composite vitamin containing deep sea fish oil is added and applied for a long time in the livestock breeding production, unsaturated fatty acid EPA and DHA can be accumulated in the organism tissues of livestock and poultry, and after the food is eaten by a human body, the health of the human body can be benefited.
Vitamin A has effects of promoting animal growth, maintaining normal function of epithelial tissue, promoting rhodopsin synthesis, maintaining normal vision, preventing nyctalopia, blindness due to daytime and dry ophthalmia, promoting normal growth and repair of skeleton, improving reproductive performance and egg yield, and enhancing immunity and wound healing. Vitamin D3 has effects in regulating calcium and phosphorus metabolism, promoting absorption and utilization of calcium and phosphorus, maintaining normal growth of bone and teeth, improving eggshell quality and growth speed, and preventing rickets and osteomalacia. DL-alpha-tocopherol acetate can maintain animal reproductive function, promote gonad development, promote conception and prevent abortion, resist oxidation, protect cell membrane integrity, increase utilization rate of sugar and protein, improve animal disease resistance, and enhance anti-stress effect.
The fructus crataegi extract is dried mature fruit extract of Crataegus Pinnatifida Bge of Crataegus of Rosaceae. Has effects of resolving food stagnation, promoting qi circulation, removing blood stasis, resisting oxidation, enhancing immunity, and inhibiting bacteria. The fatty acid contained in the feed can promote fat digestion, increase the secretion of gastric digestive enzyme to promote the digestion of nutrient substances of the feed, and has a certain regulation effect on gastrointestinal functions. It can be used for treating food stagnation, dyspepsia, and dysentery.
The Astragalus polysaccharides is extract of Astragalus membranaceus of Leguminosae, and has effects of invigorating qi, consolidating superficial resistance, arresting sweating, relieving depletion, promoting granulation, inducing diuresis, and relieving swelling. Has effects in regulating animal organism immunity, resisting virus, stress and oxidation. The astragalus polysaccharide can also increase the number of intestinal lactobacilli and bifidobacteria, can reduce the number of escherichia coli, can effectively promote the proliferation of intestinal beneficial microorganisms, and has an inhibiting effect on intestinal harmful bacteria.
The invention has the advantages of
Compared with the prior art, the invention compounds highly unsaturated fatty acids (EPA and DHA) in the deep sea fish oil with fat-soluble vitamin ADE, astragalus extract polysaccharide and hawthorn extract together, and prepares the water-soluble composite vitamin of the deep sea fish oil and the vitamin ADE for livestock and poultry through the emulsification process treatment. The compound vitamin A can promote the secretion of digestive glands, increase the activity of digestive enzymes in gastric juice, promote the synergistic absorption and utilization of fat-soluble vitamin ADE and increase the digestive absorption capacity of nutrient substances; free radicals are removed, and immunity and disease resistance are improved; promoting the growth and development of livestock and poultry and improving the feed reward; the water can be used by an intensive large-scale drinking water system, so that the absorption is faster and more thorough, the labor cost is saved, and the use is convenient and economic; the components have a synergistic effect, so that the product has more effects and higher cost performance, the breeding cost is saved, and the breeding benefit is improved.
The invention adopts the compounding of fat-soluble vitamin ADE and the deep sea fish oil containing highly unsaturated fatty acid (EPA and DHA), improves the mutual active ingredients which are easier to be absorbed by the intestinal tract in a synergic manner, greatly increases the absorption rate, more fully plays the function role and plays a better role.
The invention also provides a preparation method of the compound vitamin of the deep sea fish oil and the vitamin ADE for the livestock and the poultry, which adopts the conditions of constant temperature and constant humidity with the temperature of 25 ℃ and the humidity of 65 percent, reduces the influence of the temperature and the humidity on active ingredients, particularly the vitamin ADE ingredient, in the production and processing process, and ensures the stable quality of products.
Detailed Description
The invention will now be further described with reference to the following examples, which are not to be construed as limiting the invention in any way, and any limited number of modifications which can be made within the scope of the claims of the invention are still within the scope of the claims of the invention.
In order to explain the technical contents of the present invention in detail, the following description is made with reference to the embodiments.
Preparation of example and comparative examples
Example 1
Weighing 8.7 parts of deep sea fish oil as a raw material according to the prescription amount under the conditions of a temperature of 25 ℃ and a humidity of 65 percent at a constant temperature and a constant humidity, adding 1.72 parts of an emulsifier (Tween-80) and 0.15 part of auxiliary emulsifier ethanol, uniformly emulsifying in a stirring homogenizer, adding 0.2 part of sodium sulfite and 0.9 part of sodium salicylate, and uniformly stirring; adding the emulsified deep sea fish oil into 70 parts of glucose, adsorbing and uniformly premixing.
Weighing prescribed vitamin A acetate 4.5 parts, DL-alpha-tocopherol acetate 7.8 parts and vitamin D30.8 part of the mixture is added into 13.1 parts of glucose and is premixed evenly; 38.5 parts of astragalus polysaccharide and 7.2 parts of natural plant hawthorn extract are weighed according to the prescription amount, added into 45.7 parts of glucose and uniformly premixed.
Adding the prepared pre-mixture and 800.73 parts of the rest glucose into a three-dimensional mixer, uniformly mixing under the conditions of constant temperature and constant humidity at the temperature of 25 ℃ and the humidity of 65 percent, and subpackaging after qualified detection to obtain the glucose premix.
Comparative example 1
The formula is substantially the same as that of example 1, except that natural plant hawthorn extract components are not added, other components are not changed, the preparation method is the same as that of example 1, and the formula is implemented as follows:
Figure BDA0003563982580000051
comparative example 2
The formulation is substantially the same as that of example 1, except that the astragalus polysaccharide component is not immunized, and the other components are not changed, the preparation method is the same as that of example 1, and the formulation is carried out as follows:
Figure BDA0003563982580000052
comparative example 3
The formulation was substantially the same as the formulation of example 1, except that the marine oil ingredients were not deepened, and the other components were not changed, and the formulation was carried out as follows:
Figure BDA0003563982580000053
the preparation method comprises the following steps: under the conditions of a temperature of 25 ℃ and a humidity of 65 percent, weighing 4.5 parts of vitamin A acetate, 7.8 parts of DL-alpha-tocopherol acetate and 7.8 parts of vitamin D in prescribed amounts30.8 part of the mixture is added into 13.1 parts of glucose and is premixed evenly; 38.5 parts of astragalus polysaccharide and 7.2 parts of natural plant hawthorn extract are weighed according to the prescription amount, added into 45.7 parts of glucose and uniformly premixed.
Adding the prepared pre-mixture and 882.4 parts of the residual glucose into a three-dimensional mixer, uniformly mixing under the conditions of constant temperature and constant humidity of 25 ℃ and 65 percent of humidity, and subpackaging after the detection is qualified.
Comparative example 4
The formula is substantially the same as that of the example 1, except that the natural plant hawthorn extract and the immune astragalus polysaccharide are not added, other components are not changed, the preparation method is the same as that of the example 1, and the preparation method comprises the following steps:
8.7 parts of deep sea fish oil, 4.5 parts of vitamin A acetate, 7.8 parts of DL-alpha-tocopherol acetate
Vitamin D30.8 part of tween-80: 1.72 parts of ethanol 0.15 part
Sodium sulfite 0.2 parts sodium salicylate 0.9 parts glucose to 1000 parts
Comparative example 5
The formulation is substantially the same as that of example 1, the natural plant hawthorn extract is replaced by malt extract, other components are not changed, the preparation method is the same as that of example 1, and the formulation is implemented as follows:
Figure BDA0003563982580000061
examples 2 to 5
The preparation method refers to example 1, and the formula refers to the following table one:
watch 1
Figure BDA0003563982580000062
(II) animal breeding effect test of example and comparative example
1. The effect of example sample 1 and comparative example sample 1 on broiler growth performance was compared.
1.1 materials and methods
(1) Material
The above example sample 1 and comparative example 1 were taken as test materials of this example.
(2) Design of the scheme
160 commercial broilers with good health conditions of 7 days old are selected, randomly divided into two groups of 80 broilers, and the initial weight is taken. The experimental group feeds the sample 1 of the example with water, the addition amount of water is 1g per liter, and the water is used once a day for 28 days; the comparative group feeds comparative example 1 with drinking water, the addition amount of each liter of water is 1g, and the water is used once a day for 28 days; the experimental group and the comparison group are all raised in cages, drinking water is freely taken, two groups of daily ration complete feed are identical, the daily feeding condition and the excrement condition of the broiler are recorded, vaccine immunization is carried out regularly, a chicken house is cleaned every day, the test time is 28 days, and then the weights of the experimental group and the comparison group are weighed.
(3) Weighing method
On day 28, day 18, the full ration feed was stopped, drinking water was kept in normal supply, and the next day 10 was weighed.
1.2 results and data
TABLE-test results of the experimental group and the comparative group
Comparison group Experimental group
Initial average body weight/g (7 days old) 180.2 179.5
Average body weight/g after 28 days of the test 1956.2 1997.3
Average daily gain g/day 63.43 64.92
Average daily food intake g/day 82.9 83.8
Condition of stool The excrement with feed appears in 11 days The excrement appears in the feed in 5 days
The test result shows that:
the composite vitamin of the deep sea fish oil for livestock and poultry and the vitamin ADE is added into the process of feeding fast big-meat chickens, compared with the comparative example 1 without adding natural plant hawthorn extract, the feed intake can be increased, the digestion, absorption and utilization of nutrient substances in daily ration complete feed are promoted, the feed convenience is greatly reduced, the growth and development of broiler chickens are promoted, and the average daily gain of the broiler chickens is obviously improved.
2. Example 1 and comparative example 2 are comparative tests for the effect on broiler growth performance.
1.1 materials and methods
(1) Material
The above example sample 1 and comparative example sample 2 were taken as test materials of this example.
(2) Scheme design
180 commercial broilers with good health status and age of 7 days are selected, randomly divided into two groups of 90 broilers, and the initial weight is taken. The experimental group feeds the sample 1 of the example with water, the addition amount of water is 1g per liter, and the water is used once a day for 35 days; the comparative group feeds comparative example 2 with drinking water, the addition amount of each liter of water is 1g, and the water is used once a day for 35 days; the experimental group and the comparison group are all bred in cages, drinking water is freely taken, two groups of the daily ration complete feed are identical, the daily feeding condition of the broiler chickens, the excrement condition and the survival rate are recorded, vaccine immunization is periodically carried out, chicken houses are cleaned every day, the test time is 35 days, and then the weights of the experimental group and the comparison group are weighed.
(3) Weighing method
On day 35, day 18, the complete ration feed was stopped, drinking water was kept in normal supply, and the next day 10 was weighed.
1.2 results and data
Test results of the experimental group and the comparative group of Table II
Experimental group Comparison group
Initial average body weight/g (7 days old) 180.8 181.1
Average body weight/g after 35 days of the test 2689.2 2591.3
Average daily gain g/day 71.67 68.86
Average daily food intake g/day 109.2 106.9
Meat ratio of materials 1.52 1.55
Condition of stool The feces with feed appear in 4 days The excrement appears in the feed in 10 days
Survival rate 97.8％ 94.4％
The test result shows that:
when the compound vitamin of the deep sea fish oil for livestock and poultry and the vitamin ADE is added into the feeding process of fast big-meat chickens, compared with the comparative example 2 without the immune astragalus polysaccharide, the compound vitamin can enhance the immune disease resistance, improve the survival rate, promote the digestion, absorption and utilization of nutrient substances in daily ration complete feed, promote the growth and development of broilers, improve the average daily gain of the broilers and reduce the feed-meat ratio.
3. Example 1 and comparative example 3 are compared for the effect on broiler growth performance.
1.1 materials and methods
(1) Material
The above example sample 1 and comparative example sample 3 were taken as test materials of this example.
(2) Scheme design
100 commercial broilers with good health status and age of 7 days are selected, randomly divided into two groups, each group comprises 50 broilers, and the initial weight is taken. The experimental group feeds the sample 1 of the example with water, the addition amount of water is 1g per liter, and the water is used once a day for 35 days; the comparative group feeds comparative example 4 with drinking water, the addition amount of each liter of water is 1g, and the water is used once a day for 35 days; the experimental group and the comparison group are all raised in cages, drinking water is freely taken, two groups of daily ration complete feed are identical, the daily feeding condition, the excrement condition and the survival rate of the broiler chickens are recorded, vaccine immunization is periodically carried out, the henhouses are cleaned every day, the test time is 35 days, and then the weights of the experimental group and the comparison group are weighed.
(3) Weighing method
On day 35, day 18, the complete ration feed was stopped, drinking water was kept in normal supply, and the next day 10 was weighed.
1.2 results and data
Test results of the experimental group and the comparative group in Table III
Experimental group Comparison group
Initial average body weight/g (7 days old) 177.8 178.1
Average body weight/g after 35 days of the test 2677.3 2625.9
Average daily gain g/day 71.41 69.94
Average daily food intake g/day 107.9 106.8
Meat ratio of materials 1.51 1.53
Condition of stool The feed feces appear in 5 days in total The excrement appears in the feed in 10 days
Survival rate 98％ 94％
The test result shows that:
compared with a comparative example 3 which does not deepen the sea fish oil, the compound vitamin of the deep sea fish oil and the vitamin ADE for the livestock and poultry is added into the process of feeding fast big-meat chickens, so that the nutrient digestion and absorption of the vitamin ADE and nutrient substances in the daily ration complete feed can be improved, the bone growth is promoted, the growth and development of the broilers are accelerated, the immunity and disease resistance are enhanced, the stress is reduced, the death rate is reduced, the average daily gain of the broilers is improved, the feed-meat ratio is reduced, and the breeding benefit is improved.
4. Example 1 and comparative example 4 are compared for the effect on broiler growth performance.
1.1 materials and methods
(1) Material
The above example sample 1 and comparative example sample 4 were taken as test materials of this example.
(2) Scheme design
200 commercial broilers with good health conditions and age of 7 days are selected, randomly divided into two groups, each group is 100, and the initial weight is taken. The experimental group feeds the sample 1 of the example with water, the addition amount of water is 1g per liter, and the water is used once a day for 28 days; the comparative group feeds comparative example 4 with drinking water, the addition amount of each liter of water is 1g, and the water is used once a day for 28 days; the experimental group and the comparison group are all raised in cages, drinking water is freely taken, two groups of daily ration complete feed are identical, the daily feeding condition, the excrement condition and the survival rate of the broiler chickens are recorded, vaccine immunization is periodically carried out, the henhouses are cleaned every day, the test time is 28 days, and then the weights of the experimental group and the comparison group are weighed.
(3) Weighing method
On day 28, day 18, the full ration feed was stopped, drinking water was kept in normal supply, and the next day 10 was weighed.
1.2 results and data
Table four test results of the experimental group and the comparative group
Comparison group Experimental group
Initial average body weight/g (7 days old) 179.2 178.8
Average body weight/g after 28 days of the test 1939.1 1987.7
Average daily gain g/day 62.85 64.60
Average daily food intake g/day 81.4 82.5
Meat ratio of materials 1.30 1.28
Condition of stool The feed excrement appears in 18 days in total The feces with feed appear in 6 days
Survival rate 92％ 97％
The test result shows that:
compared with a comparative sample 4 without adding natural plant hawthorn extract and immune astragalus polysaccharide, the composite vitamin of the deep sea fish oil for livestock and poultry and the vitamin ADE can be added into the feeding process of fast large broiler chickens, can fully digest, absorb and utilize nutrient substances in daily ration complete feed, accelerate the growth and development of the broiler chickens, enhance the immunity disease resistance, obviously improve the survival rate and the average daily gain of the broiler chickens, greatly reduce the feed-meat ratio and improve the breeding benefit.
5. Example 1 and comparative example 5 are compared for the effect on broiler growth performance.
1.1 materials and methods
(1) Material
The above example sample 1 and comparative example 5 were taken as test materials of this example.
(2) Scheme design
100 commercial broilers with good health status and age of 7 days are selected, randomly divided into two groups, each group comprises 50 broilers, and the initial weight is taken. The experimental group feeds the sample 1 of the example with water, the addition amount of water is 1g per liter, and the water is used once a day for 35 days; the comparative group feeds comparative example 4 with drinking water, the addition amount of each liter of water is 1g, and the water is used once a day for 35 days; the experimental group and the comparison group are all bred in cages, drinking water is freely taken, two groups of the daily ration complete feed are identical, the daily feeding condition of the broiler chickens, the excrement condition and the survival rate are recorded, vaccine immunization is periodically carried out, chicken houses are cleaned every day, the test time is 35 days, and then the weights of the experimental group and the comparison group are weighed.
(3) Weighing method
On day 35, day 18, the complete ration feed was stopped, drinking water was kept in normal supply, and the next day 10 was weighed.
1.2 results and data
Table five test results of the experimental group and the comparative group
Experimental group Comparison group
Initial average body weight/g (7 days old) 182.3 181.9
Average body weight/g after 35 days of the test 2752.4 2678.7
Average daily gain g/day 73.43 71.91
Average daily food intake g/day 112.5 110.4
Meat ratio of materials 1.53 1.55
Condition of stool The excrement appears in the feed in 5 days The feed excrement appears in 8 days
Survival rate 98％ 96％
The test result shows that:
the compound vitamin of the deep sea fish oil for livestock and poultry and the vitamin ADE is added into the process of feeding fast big-meat chickens, compared with a comparative example 5 of adding a natural plant malt extract, the compound vitamin can enhance the digestion and absorption functions of animal organisms, the absorption and conversion rate of nutrient substances in the vitamin ADE and daily ration complete feed is higher, the feed is reduced, the bone growth is promoted, the growth and development of broiler chickens are accelerated, the average daily gain of the broiler chickens is increased, the feed conversion ratio is reduced, the immunity and the resistance of organisms can be enhanced, the survival rate is increased, and the economic benefit of breeding is improved.
According to the test data, the compound vitamin of the deep sea fish oil and the vitamin ADE for the livestock and the poultry is prepared by scientifically compounding and refining the fat-soluble vitamin ADE, the deep sea fish oil containing highly unsaturated fatty acids (EPA and DHA), the immune astragalus polysaccharide and the natural plant hawthorn extract. The feed additive can improve the digestion, absorption and utilization rate of nutrient substances in vitamin ADE and daily ration complete feed, promote bone growth, accelerate the growth and development of broiler chickens, enhance the immunity and disease resistance, reduce stress, reduce the death rate, improve the average daily gain of the broiler chickens, reduce the feed-meat ratio and greatly improve the breeding benefit.

Claims (7)

1. The composite vitamin composition of deep sea fish oil and vitamin ADE for livestock and poultry is characterized by comprising the following components in parts by weight:
5.5-10.5 parts of deep sea fish oil;
vitamin AD3E7.4-17.8 parts;
20.8-56.3 parts of astragalus extract polysaccharide;
1.8-9.9 parts of hawthorn extract;
the vitamin AD3E is vitamin A or vitamin D3Vitamin E;
vitamin A and vitamin D3The weight ratio of the vitamin E is as follows: 2.2-6: 0.4-1: 5 to 10.
2. The deep sea fish oil and vitamin ADE composite vitamin composition for livestock and poultry according to claim 1, characterized in that vitamin A and vitamin D3The weight ratio of the vitamin E is as follows: 3-5: 0.5-0.8: 6-8.
3. The deep sea fish oil and vitamin ADE compound vitamin for livestock and poultry according to claim 1, which is characterized by comprising the following components in parts by weight:
7-9 parts of deep sea fish oil;
vitamin AD3E9-14 parts;
25-45 parts of astragalus extract polysaccharide;
3-8 parts of hawthorn extract.
4. The vitamin complex composition of deep sea fish oil and vitamin ADE for livestock and poultry according to claim 1, which is characterized by further comprising an emulsifier: 0.5-2.5 parts; 0.5-1.5 parts of antioxidant.
5. The deep sea fish oil and vitamin ADE composite vitamin composition for livestock and poultry according to claim 4, wherein the emulsifier comprises: the weight ratio of tween-80 to co-emulsifier ethanol is 90-96: 4-10;
the antioxidant is one or more of sodium sulfite, sodium metabisulfite or sodium salicylate.
6. The vitamin complex composition of deep sea fish oil and vitamin ADE for livestock and poultry according to claim 4, characterized by further comprising 963.5-901.5 parts of glucose.
7. The preparation method of the vitamin complex composition of deep sea fish oil and vitamin ADE for livestock and poultry according to claim 6 is characterized by comprising the following steps:
step 1: weighing the deep sea fish oil as the raw material according to the prescription amount, adding a proper amount of emulsifier, stirring uniformly for emulsification, adding the antioxidant, and stirring uniformly;
and 2, step: adding the emulsified deep sea fish oil prepared in the step 1 into a certain weight part of glucose, and uniformly premixing;
and step 3: weighing the raw material vitamin AD according to the prescription amount3E, adding the mixture into a certain weight part of glucose, and uniformly premixing;
and 4, step 4: weighing the astragalus extract polysaccharide serving as a raw material in a prescription amount, adding the astragalus extract polysaccharide into glucose in a certain weight part, and uniformly premixing;
and 5: weighing a formula amount of raw material hawthorn extract, adding the raw material hawthorn extract into a certain weight part of glucose, and uniformly premixing;
step 6: and (3) weighing the pre-mixture prepared in the steps (2), (3), (4) and (5), adding the rest glucose according to the proportion of the prescription, uniformly mixing, and subpackaging after qualified detection.
CN202210297304.3A 2022-03-24 2022-03-24 Composite vitamin composition and preparation method thereof Pending CN114568589A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104304679A (en) * 2014-10-27 2015-01-28 广东金品动物营养有限公司 Multivitamin C, E immune polysaccharide microemulsion preparation and preparation method and application of preparation
CN104366026A (en) * 2014-10-20 2015-02-25 山东绿都安特动物药业有限公司 Traditional-Chinese-medicine extract and vitamin premix immunoenhancer for poultries
CN105770067A (en) * 2016-04-19 2016-07-20 河北天元药业有限公司 Traditional Chinese medicine composition capable of improving immunity of livestock and preparing method and application thereof
CN111972548A (en) * 2020-08-29 2020-11-24 四川渴望生物科技有限公司 Immunopotentiator for pigs

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104366026A (en) * 2014-10-20 2015-02-25 山东绿都安特动物药业有限公司 Traditional-Chinese-medicine extract and vitamin premix immunoenhancer for poultries
CN104304679A (en) * 2014-10-27 2015-01-28 广东金品动物营养有限公司 Multivitamin C, E immune polysaccharide microemulsion preparation and preparation method and application of preparation
CN105770067A (en) * 2016-04-19 2016-07-20 河北天元药业有限公司 Traditional Chinese medicine composition capable of improving immunity of livestock and preparing method and application thereof
CN111972548A (en) * 2020-08-29 2020-11-24 四川渴望生物科技有限公司 Immunopotentiator for pigs

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