CN114452241A - Probiotic small-molecule facial mask and preparation method thereof - Google Patents

Probiotic small-molecule facial mask and preparation method thereof Download PDF

Info

Publication number
CN114452241A
CN114452241A CN202210258102.8A CN202210258102A CN114452241A CN 114452241 A CN114452241 A CN 114452241A CN 202210258102 A CN202210258102 A CN 202210258102A CN 114452241 A CN114452241 A CN 114452241A
Authority
CN
China
Prior art keywords
probiotic
mask
micromolecular
micromolecule
facial mask
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210258102.8A
Other languages
Chinese (zh)
Inventor
杨立娜
王子义
丁文文
魏淑萍
李丽
吴星会
曹淑芳
王胜男
宋虹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bohai University
Original Assignee
Bohai University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bohai University filed Critical Bohai University
Priority to CN202210258102.8A priority Critical patent/CN114452241A/en
Publication of CN114452241A publication Critical patent/CN114452241A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212Face masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/733Alginic acid; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/81Preparation or application process involves irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

Abstract

The invention discloses a probiotic micromolecule mask and a preparation method thereof, and the probiotic micromolecule mask comprises non-woven fabrics and probiotic micromolecule mask liquid soaked in the non-woven fabrics, wherein the probiotic micromolecule mask liquid consists of the following components in percentage by mass: 4.8-11.2% of humectant, 0.3-0.65% of thickening agent, 2-5% of active ingredient, 0.5% of preservative and the balance of deionized water, wherein the active ingredient is soybean yellow serofluid probiotic fermentation liquor. Compared with the prior art, the mask takes the micromolecule nutrient substances metabolized by the probiotics as the main components, the bioactivity of the yellow serofluid is improved by the fermentation of the probiotics, and the micromolecule nutrient substances generated by the metabolism of the probiotics are easier to be absorbed by the skin, so that the function of skin cells is ensured; in addition, the nutrient substances in the yellow serofluid fermentation product also increase the nutrient factors of the mask, and the mask is suitable for various skin types and is wide in audience population, so that the problems of emission, pollution, cyclic utilization and the like of the soybean yellow serofluid are solved, the profit of an enterprise can be increased, and the local economic development is promoted.

Description

Probiotic small-molecule facial mask and preparation method thereof
Technical Field
The invention relates to the technical field of skin care products, in particular to a probiotic micro-molecular facial mask and a preparation method thereof.
Background
The structure of skin includes the epidermis, dermis, and subcutaneous fat. The dermis contains collagen, elastin, and other fibrous tissues. People face computers and mobile phone electronic equipment for a long time, the electronic equipment is easy to generate static electricity to attract dust or tiny particles to be attached to the surface of skin, and in addition, work and rest are irregular, the epidermis is easy to dry, and melanin precipitation is aggravated. With the age, the epidermis layer becomes thinner gradually, the metabolism of the skin is slowed down, the moisturizing factor in the dermis layer is reduced, the function of elastic fiber and collagen fiber in the dermis layer is reduced, the elasticity is weakened, and wrinkles appear; in addition, the active biological enzyme in the human body is reduced, a large number of free radicals destroy the cells of the human body, and the process of skin aging is accelerated.
The mask market in China enters a mature stage, and the quality of the mask is also improved by consumers, but the current problem is that the essence substances in the mask cannot be absorbed by the skin, such as collagen in the mask, and macromolecular protein needs to be decomposed into amino acid to penetrate skin cells, so that the mask with nutrient components capable of penetrating the skin cells is necessary.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provides a probiotic micro-molecular mask and a preparation method thereof.
In order to achieve the purpose, the invention is implemented according to the following technical scheme:
the probiotic micromolecule mask comprises non-woven fabrics and probiotic micromolecule mask liquid soaked in the non-woven fabrics, wherein the probiotic micromolecule mask liquid consists of the following components in percentage by mass:
2-5% of active ingredient, 4.8-11.2% of humectant, 0.3-0.65% of thickener, 0.5% of preservative and the balance of deionized water, wherein the active ingredient is soybean whey probiotic fermentation liquor which contains gamma-aminobutyric acid, citric acid, tartaric acid, lactic acid, succinic acid, active isoflavone, antioxidant peptide, free small molecular phenolic substance and the like, has strong antioxidant function, is easier to be absorbed by skin and can promote skin whitening.
Preferably, the humectant consists of glycerol, trehalose, anhydrous betaine and sodium hydroxymethyl cellulose, and the mass percentages of the glycerol, the trehalose, the anhydrous betaine and the sodium hydroxymethyl cellulose in the probiotic micromolecular facial mask liquid are respectively as follows: 2-5% of glycerol, 2-5% of trehalose, 0.4-0.7% of anhydrous betaine and 0.4-0.5% of sodium hydroxymethyl cellulose.
Preferably, the thickening agent consists of sodium alginate, xanthan gum and triethanolamine, and the mass percentages of the sodium alginate, the xanthan gum and the triethanolamine in the probiotic micromolecular mask liquid are respectively as follows: 0.2 to 0.3 percent of sodium alginate, 0.05 to 0.2 percent of xanthan gum and 0.05 to 0.15 percent of triethanolamine.
Preferably, the preservative is phenoxyethanol.
In addition, the invention also provides a preparation method of the probiotic micromolecule mask, which comprises the following steps:
s1, placing 0.5-1L yellow serofluid in an open glass container at 10%3-105Irradiating and sterilizing for 30s under W pulse strong light, transferring into a fermentation tank after sterilization, inoculating 5% of antioxidant whitening type lactobacillus paracasei, 1% of fresh-scent type hansenula polymorpha and 1% of fresh-scent type golden flower fungus, and fermenting for 24-48h to obtain soybean yellow serofluid probiotic fermentation liquor;
s2, accurately weighing deionized water of the probiotic micromolecular mask liquid according to the weight percentage, adding part of the deionized water into a 250mL three-necked bottle, keeping the temperature at 70 ℃ for 20min, sequentially adding a humectant and a thickener of the probiotic micromolecular mask liquid accurately weighed according to the weight percentage, stirring until the mixture is dissolved, and cooling to 40 ℃ after irradiation sterilization is finished to obtain a phase A;
s3, adding the rest deionized water into a 100mL three-necked bottle under stirring, sequentially adding the preservative of the probiotic micromolecular mask liquid and the soybean yellow serofluid probiotic fermentation liquid which are accurately weighed according to the weight percentage, and stirring until the preservative and the soybean yellow serofluid probiotic fermentation liquid are dissolved to obtain a phase B;
s4, slowly adding the phase B into the phase A, and continuously stirring until the solution is clear and uniform to obtain the probiotic micromolecular mask solution;
s5, pumping out air in the probiotic small-molecule facial mask liquid through vacuum defoaming;
and S6, the non-woven fabric is irradiated and sterilized and then is immersed into the defoamed probiotic micro-molecular mask liquid, so that the probiotic micro-molecular mask is obtained.
Preferably, the radiation dose during radiation sterilization is 5k-10 kGy.
Compared with the prior art, the mask takes the micromolecule nutrient substances metabolized by the probiotics as the main components, the bioactivity of the yellow serofluid is improved by the fermentation of the probiotics, and the micromolecule nutrient substances generated by the metabolism of the probiotics are easier to be absorbed by the skin, so that the function of skin cells is ensured; in addition, the nutrient substances in the yellow serofluid fermentation product also increase the nutrient factors of the mask, and the mask is suitable for various skin types and is wide in audience population, so that the problems of emission, pollution, cyclic utilization and the like of the soybean yellow serofluid are solved, the profit of an enterprise can be increased, and the local economic development is promoted.
Drawings
FIG. 1 is a graph showing the change in facial mask liquid mass within 30min of the facial mask prepared in example 3 of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. The specific embodiments described herein are merely illustrative of the invention and do not limit the invention.
Example 1
Placing 0.5-1L yellow serofluid in an open glass container at 10 deg.C3-105Irradiating and sterilizing for 30s under W pulse strong light, transferring into a fermentation tank after sterilization, inoculating 5% (V/V) of antioxidant whitening lactobacillus paracasei, 1% (V/V) of fresh-scent Hansenula and 1% (V/V) of fresh-scent golden flower, and fermenting for 24-48h to obtain soybean yellow serofluid probiotic fermentation liquor;
accurately weighing deionized water of the probiotic micromolecular mask liquid according to the weight percentage, adding 800mL of deionized water into a three-necked bottle, keeping the temperature at 70 ℃ for 20min, sequentially adding 20 g of glycerol, 20 g of trehalose, 4 g of anhydrous betaine, 4 g of sodium carboxymethylcellulose, 2 g of sodium alginate, 0.5 g of xanthan gum and 0.5 g of triethanolamine, stirring until the mixture is dissolved, and cooling to 40 ℃ after irradiation sterilization to obtain a phase A;
adding 124mL of deionized water into a three-mouth bottle under stirring, sequentially adding 5 g of phenoxyethanol and 20 g of soybean whey probiotic fermentation liquor, and stirring until the materials are dissolved to obtain a phase B;
slowly adding the phase B into the phase A, and continuously stirring until the solution is clear and uniform to obtain the probiotic micromolecular mask solution;
pumping out air in the probiotic micromolecular mask liquid through vacuum defoaming;
and (3) irradiating and sterilizing the non-woven fabric, and then soaking the non-woven fabric into the defoamed probiotic micromolecular mask solution to obtain the probiotic micromolecular mask.
Example 2
Placing 0.5-1L yellow serofluid in an open glass container at 10 deg.C3-105Irradiating and sterilizing for 30s under W pulse strong light, transferring into a fermentation tank after sterilization, inoculating 5% (V/V) of antioxidant whitening lactobacillus paracasei, 1% (V/V) of fresh-scent Hansenula and 1% (V/V) of fresh-scent golden flower, and fermenting for 24-48h to obtain soybean yellow serofluid probiotic fermentation liquor;
accurately weighing deionized water of the probiotic micromolecular mask liquid according to the weight percentage, adding 700mL of deionized water into a three-necked bottle, keeping the temperature at 70 ℃ for 20min, sequentially adding 50 g of glycerol, 50 g of trehalose, 7 g of anhydrous betaine, 5 g of sodium carboxymethylcellulose, 3 g of sodium alginate, 2 g of xanthan gum and 1.5 g of triethanolamine accurately weighed according to the weight percentage, stirring until the mixture is dissolved, and cooling to 40 ℃ after irradiation sterilization is finished to obtain a phase A;
adding 126.5mL of deionized water into a three-mouth bottle under stirring, sequentially adding 5 g of phenoxyethanol and 50 g of soybean whey probiotic fermentation liquor which are accurately weighed according to the weight percentage, and stirring until the materials are dissolved to obtain a phase B;
slowly adding the phase B into the phase A, and continuously stirring until the solution is clear and uniform to obtain the probiotic micromolecular mask solution;
pumping out air in the probiotic micromolecular mask liquid through vacuum defoaming;
and (3) irradiating and sterilizing the non-woven fabric, and then soaking the non-woven fabric into the defoamed probiotic micromolecular mask solution to obtain the probiotic micromolecular mask.
Example 3
Placing 0.5-1L yellow serofluid in an open glass container at 10 deg.C3-105Irradiating and sterilizing for 30s under W pulse strong light, transferring into a fermentation tank after sterilization, inoculating 5% (V/V) of antioxidant whitening lactobacillus paracasei, 1% (V/V) of fresh-scent Hansenula and 1% (V/V) of fresh-scent golden flower, and fermenting for 24-48h to obtain soybean yellow serofluid probiotic fermentation liquor;
accurately weighing deionized water of the probiotic micromolecular mask liquid according to the weight percentage, adding 650mL of deionized water into a three-necked bottle, keeping the temperature at 70 ℃ for 20min, sequentially adding 30 g of glycerol, 30 g of trehalose, 5 g of anhydrous betaine, 4.5 g of sodium carboxymethylcellulose, 2.5 g of sodium alginate, 1.5 g of xanthan gum and 1 g of triethanolamine accurately weighed according to the weight percentage, stirring until the mixture is dissolved, and cooling to 40 ℃ after irradiation sterilization is finished to obtain a phase A;
adding 230.5mL of deionized water into a three-mouth bottle under stirring, sequentially adding 5 g of phenoxyethanol and 40 g of soybean whey probiotic fermentation liquor which are accurately weighed according to weight percentage, and stirring until the materials are dissolved to obtain a phase B;
slowly adding the phase B into the phase A, and continuously stirring until the solution is clear and uniform to obtain the probiotic micromolecular mask solution;
pumping out air in the probiotic micromolecular mask liquid through vacuum defoaming;
and (3) irradiating and sterilizing the non-woven fabric, and then soaking the non-woven fabric into the defoamed probiotic micromolecular mask solution to obtain the probiotic micromolecular mask.
In the mask industry, basic physicochemical indexes of the mask are shown in table 1, and in order to verify the physicochemical indexes of the mask of the present invention, the mask prepared in example 3 was used for detection.
TABLE 1
Figure BDA0003549521090000061
The facial mask prepared in the embodiment 3 belongs to a paste facial mask, the pH value is 6.3 at room temperature, the physical and chemical indexes of the facial mask are 3.5-8.5, and other indexes all meet the national standards of the facial mask through detection, so that the skin cannot be damaged. In addition, the oxidation resistance of the facial mask in example 3 was tested, working solution was prepared according to the kit requirements, 10 μ L of blank, standard and sample solutions were added to a 96-well plate, left to stand at room temperature for 10min, and absorbance was measured at 405nm, and the radical scavenging rate of the finally obtained facial mask solution reached 10%, demonstrating that the facial mask solution had oxidation resistance, and the oxidation resistance was gradually improved with the increase in facial mask solution concentration, and skin oxidation was significantly inhibited.
Further, in order to verify whether the mask prepared in example 3 has whitening properties, a human skin test was performed, 10 volunteers meeting the requirements were selected, the same test area of 2cm × 2cm was selected on the face, the sample solution was applied to the test area, the test was performed after 20min, data was collected using a tristimulus colorimeter, and the operation was repeated five times. The test is carried out at nine-10 am every monday, and the test period is 4 weeks. Blank groups were compared with glycerol. The final colorimetric results are shown in tables 2, 3, 4 and 5.
TABLE 2 colorimetric results of volunteers in the first week
Figure BDA0003549521090000071
TABLE 3 colorimetric results of volunteers in the second week
Figure BDA0003549521090000072
Figure BDA0003549521090000081
TABLE 4 third week volunteer colorimetric results
Figure BDA0003549521090000082
TABLE 5 colorimetric results of fourth volunteer
Figure BDA0003549521090000083
According to the literature, the L value and the melanin content of the human skin are in an exponential negative correlation, the a value and the b value and the melanin content of the human skin are in an exponential positive correlation, and after four-week research, according to tables 2, 3, 4 and 5, the L value of the volunteer shows an increasing trend, and the a value and the b value show a decreasing trend. Therefore, the facial mask solution of example 3 has significant whitening properties.
In addition, in order to verify whether the facial mask prepared in example 3 has moisture retention, the facial mask liquid quality was changed within 30min, and the test result is shown in fig. 1, and it can be seen from fig. 1 that the facial mask lost 9.16% of its quality within 30min, and has a good moisture retention effect.
In summary, the probiotic micro-molecular facial mask disclosed by the invention meets the national standards of facial masks, and has whitening, moisturizing and antioxidant effects on skin.
The technical solution of the present invention is not limited to the limitations of the above specific embodiments, and all technical modifications made according to the technical solution of the present invention fall within the protection scope of the present invention.

Claims (6)

1. The utility model provides a probiotic micromolecule facial mask, includes the non-woven fabrics and immerses the probiotic micromolecule facial mask liquid of non-woven fabrics, its characterized in that: the probiotic micromolecular mask liquid consists of the following components in percentage by mass:
2-5% of active ingredient, 4.8-11.2% of humectant, 0.3-0.65% of thickening agent, 0.5% of preservative and the balance of deionized water, wherein the active ingredient is soybean yellow serofluid probiotic fermentation liquor.
2. The probiotic small molecule facial mask of claim 1, characterized in that: the moisturizing agent is composed of glycerol, trehalose, anhydrous betaine and sodium hydroxymethyl cellulose, and the mass percentages of the glycerol, the trehalose, the anhydrous betaine and the sodium hydroxymethyl cellulose in the probiotic micromolecular mask liquid are respectively as follows: 2-5% of glycerol, 2-5% of trehalose, 0.4-0.7% of anhydrous betaine and 0.4-0.5% of sodium hydroxymethyl cellulose.
3. The probiotic small molecule facial mask of claim 1, characterized in that: the thickening agent consists of sodium alginate, xanthan gum and triethanolamine, and the mass percentages of the sodium alginate, the xanthan gum and the triethanolamine in the probiotic micromolecular mask liquid are respectively as follows: 0.2 to 0.3 percent of sodium alginate, 0.05 to 0.2 percent of xanthan gum and 0.05 to 0.15 percent of triethanolamine.
4. The probiotic small molecule facial mask of claim 1, characterized in that: the preservative is phenoxyethanol.
5. A method for preparing a probiotic small molecule facial mask according to any one of claims 1 to 4, characterized by comprising the following steps:
s1, placing 0.5-1L yellow serofluid in an open glass container at 10%3-105Irradiating and sterilizing for 30s under W pulse strong light, transferring into a fermentation tank after sterilization, inoculating 5% of antioxidant whitening type lactobacillus paracasei, 1% of fresh-scent type hansenula polymorpha and 1% of fresh-scent type golden flower fungus, and fermenting for 24-48h to obtain soybean yellow serofluid probiotic fermentation liquor;
s2, accurately weighing deionized water of the probiotic micromolecular mask liquid according to the weight percentage, adding part of the deionized water into a 250mL three-necked bottle, keeping the temperature at 70 ℃ for 20min, sequentially adding a humectant and a thickener of the probiotic micromolecular mask liquid accurately weighed according to the weight percentage, stirring until the mixture is dissolved, and cooling to 40 ℃ after irradiation sterilization is finished to obtain a phase A;
s3, adding the rest deionized water into a 100mL three-necked bottle under stirring, sequentially adding the preservative of the probiotic micromolecular mask liquid and the soybean yellow serofluid probiotic fermentation liquid which are accurately weighed according to the weight percentage, and stirring until the preservative and the soybean yellow serofluid probiotic fermentation liquid are dissolved to obtain a phase B;
s4, slowly adding the phase B into the phase A, and continuously stirring until the solution is clear and uniform to obtain the probiotic micromolecular mask solution;
s5, pumping out air in the probiotic micro-molecular facial mask liquid through vacuum defoaming;
and S6, the non-woven fabric is irradiated and sterilized and then is immersed into the defoamed probiotic micro-molecular mask liquid, so that the probiotic micro-molecular mask is obtained.
6. The method for preparing the probiotic small molecule facial mask according to claim 1, is characterized in that: the radiation dose during radiation sterilization is 5k-10 kGy.
CN202210258102.8A 2022-03-16 2022-03-16 Probiotic small-molecule facial mask and preparation method thereof Pending CN114452241A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210258102.8A CN114452241A (en) 2022-03-16 2022-03-16 Probiotic small-molecule facial mask and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210258102.8A CN114452241A (en) 2022-03-16 2022-03-16 Probiotic small-molecule facial mask and preparation method thereof

Publications (1)

Publication Number Publication Date
CN114452241A true CN114452241A (en) 2022-05-10

Family

ID=81418294

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210258102.8A Pending CN114452241A (en) 2022-03-16 2022-03-16 Probiotic small-molecule facial mask and preparation method thereof

Country Status (1)

Country Link
CN (1) CN114452241A (en)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015012421A1 (en) * 2013-07-23 2015-01-29 서원대학교 산학협력단 Method for producing fermented material using complex strains derived from human body and functional cosmetic composition containing the fermented material
CN106361616A (en) * 2016-11-07 2017-02-01 湖南德魅信息技术有限公司 Golden flower fungus, tea and toadstool facial mask and preparation method thereof
CN106858597A (en) * 2017-02-07 2017-06-20 张贵林 Bean product waste water is made as surfactant and nutrition fortifier and its application
WO2019059668A2 (en) * 2017-09-22 2019-03-28 건국대학교 산학협력단 Composition for skin, containing, as active ingredient, milk cream liquid fermented by lactic acid bacteria
US20210052486A1 (en) * 2019-08-22 2021-02-25 Glac Biotech Co., Ltd. Skin-whitening composition with fermentation metabolite of lactic acid bacterium and applications thereof
CN112826769A (en) * 2019-11-22 2021-05-25 广州悦妆生物科技有限公司 A facial mask with effects of improving facial flora, relieving, repairing and keeping moisture
CN113249233A (en) * 2021-06-29 2021-08-13 北京百奥茵诺生物科技有限公司 Eurotium cristatum and microbial inoculum and application thereof
CN113355372A (en) * 2021-06-10 2021-09-07 苏州金记食品有限公司 Process for purifying soybean whey and extracting soybean isoflavone aglycone
CN113499305A (en) * 2021-07-08 2021-10-15 安婕妤化妆品科技股份有限公司 Plant source moisturizing mask and preparation method thereof
CN113930361A (en) * 2021-07-22 2022-01-14 华熙生物科技股份有限公司 Fermentation medium of lactobacillus paracasei and application thereof

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015012421A1 (en) * 2013-07-23 2015-01-29 서원대학교 산학협력단 Method for producing fermented material using complex strains derived from human body and functional cosmetic composition containing the fermented material
CN106361616A (en) * 2016-11-07 2017-02-01 湖南德魅信息技术有限公司 Golden flower fungus, tea and toadstool facial mask and preparation method thereof
CN106858597A (en) * 2017-02-07 2017-06-20 张贵林 Bean product waste water is made as surfactant and nutrition fortifier and its application
WO2019059668A2 (en) * 2017-09-22 2019-03-28 건국대학교 산학협력단 Composition for skin, containing, as active ingredient, milk cream liquid fermented by lactic acid bacteria
US20210052486A1 (en) * 2019-08-22 2021-02-25 Glac Biotech Co., Ltd. Skin-whitening composition with fermentation metabolite of lactic acid bacterium and applications thereof
CN112481148A (en) * 2019-08-22 2021-03-12 丰华生物科技股份有限公司 Composition containing lactic acid bacteria fermentation product for whitening efficacy and application thereof
CN112826769A (en) * 2019-11-22 2021-05-25 广州悦妆生物科技有限公司 A facial mask with effects of improving facial flora, relieving, repairing and keeping moisture
CN113355372A (en) * 2021-06-10 2021-09-07 苏州金记食品有限公司 Process for purifying soybean whey and extracting soybean isoflavone aglycone
CN113249233A (en) * 2021-06-29 2021-08-13 北京百奥茵诺生物科技有限公司 Eurotium cristatum and microbial inoculum and application thereof
CN113499305A (en) * 2021-07-08 2021-10-15 安婕妤化妆品科技股份有限公司 Plant source moisturizing mask and preparation method thereof
CN113930361A (en) * 2021-07-22 2022-01-14 华熙生物科技股份有限公司 Fermentation medium of lactobacillus paracasei and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
于冰等: "《混合菌种发酵大豆黄浆水的工艺优化》", 《粮油食品科技》 *

Similar Documents

Publication Publication Date Title
CN110680774B (en) Preparation method of jasmine double-bacterium fermented cosmetic and application of product
CN110141527B (en) Preparation method of nutritional keratin mask
CN115105452B (en) Black tea fermentation filtrate and preparation method and application thereof
CN111214427B (en) Acid-free skin refreshing composition, preparation method thereof and essence containing composition
CN109939064B (en) Essence containing probiotic fermentation metabolite and application of essence in cosmetics
CN107095843A (en) A kind of facial mask containing fermented tea
CN113855603A (en) Combined fermentation product, skin external preparation containing same, and preparation method and application of combined fermentation product
CN112516058A (en) Amino acid-loaded modified amniotic membrane mask and preparation method thereof
CN113384515A (en) Lactobacillus fermentation lysate, preparation method and application thereof, and skin external preparation containing lactobacillus fermentation lysate
CN110368337B (en) Facial mask containing rose hip extract and preparation method
CN113648274B (en) Anti-aging composition and preparation method and application thereof
CN109394640B (en) Enzyme skin care composition and application thereof
Schmidt et al. Cellulose decomposition in soil burial beds: I. Soil properties in relation to cellulose degradation
CN114452241A (en) Probiotic small-molecule facial mask and preparation method thereof
CN111358748B (en) Mask essence containing date palm seed extract and preparation method thereof
CN113398045A (en) Anti-aging and relieving aloe fermented product and preparation method and application thereof
CN112043619A (en) Peptide composition with repairing effect and preparation method and application thereof
CN109846798B (en) Composition for tightening skin and cosmetic containing same
CN109394595A (en) Facial mask essence with deep water supplement and barrier reparation
CN112006947B (en) Seaweed fermentation liquor with multiple skin care effects and preparation method thereof
CN114588091A (en) Preparation method of Hami melon fermentation raw pulp and application of Hami melon fermentation raw pulp in cosmetics
CN108403474A (en) A kind of preparation of soy molasses biology cellulose moisture saver mask
CN112870114A (en) Natural moisturizing composition and preparation method thereof
CN113244140A (en) Composition for regulating skin micro-ecological balance and application and preparation method thereof
CN111544352A (en) Tremella-ganoderma lucidum composite fermentation product, cosmetic composition with anti-aging effect and preparation method and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination