CN114375297A - Una亚酰胺及其用途 - Google Patents

Una亚酰胺及其用途 Download PDF

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Publication number
CN114375297A
CN114375297A CN202080055883.XA CN202080055883A CN114375297A CN 114375297 A CN114375297 A CN 114375297A CN 202080055883 A CN202080055883 A CN 202080055883A CN 114375297 A CN114375297 A CN 114375297A
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substituted
unsubstituted
oligonucleotide
cases
compound
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文卡塔·拉马纳·多帕拉普迪
迈克尔·卡拉米安·科克伦
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Atrem Therapy Company
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Avidity Biosciences Inc
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    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN202080055883.XA 2019-06-06 2020-06-05 Una亚酰胺及其用途 Pending CN114375297A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962858289P 2019-06-06 2019-06-06
US62/858,289 2019-06-06
PCT/US2020/036420 WO2020247818A1 (en) 2019-06-06 2020-06-05 Una amidites and uses thereof

Publications (1)

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CN114375297A true CN114375297A (zh) 2022-04-19

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US (2) US12006499B2 (https=)
EP (1) EP3980437A4 (https=)
JP (2) JP7581252B2 (https=)
KR (1) KR20220019259A (https=)
CN (1) CN114375297A (https=)
AU (1) AU2020287880B2 (https=)
CA (1) CA3142337A1 (https=)
WO (1) WO2020247818A1 (https=)

Cited By (2)

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WO2024175013A1 (zh) * 2023-02-21 2024-08-29 成都先导药物开发股份有限公司 核苷酸类似物及其制备方法和用途
WO2024235124A1 (zh) * 2023-05-12 2024-11-21 北京炫景瑞医药科技有限公司 修饰的核苷类似物及其用途与含核苷酸类似物的双链寡核苷酸及其用途

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EP3691657A4 (en) 2017-10-04 2021-07-21 Avidity Biosciences, Inc. NUCLEIC ACID POLYPEPTIDE COMPOSITIONS AND USES THEREOF
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
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CN114375296A (zh) 2019-06-06 2022-04-19 艾维迪提生物科学公司 核酸多肽组合物及其用途
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JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス，インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
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WO2023034870A2 (en) 2021-09-01 2023-03-09 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing dmpk expression
CN118265544A (zh) * 2021-09-16 2024-06-28 艾维迪提生物科学公司 治疗面肩肱型肌营养不良的组合物和方法
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