CN114344435A - Thrombolytic oral bacteriostatic spray and preparation method thereof - Google Patents

Thrombolytic oral bacteriostatic spray and preparation method thereof Download PDF

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Publication number
CN114344435A
CN114344435A CN202210025043.XA CN202210025043A CN114344435A CN 114344435 A CN114344435 A CN 114344435A CN 202210025043 A CN202210025043 A CN 202210025043A CN 114344435 A CN114344435 A CN 114344435A
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parts
ginseng
white spirit
thrombolytic
container
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CN202210025043.XA
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Chinese (zh)
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李书勇
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Zhongyoushangpin Guangzhou Biotechnology Co ltd
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Zhongyoushangpin Guangzhou Biotechnology Co ltd
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Abstract

The invention relates to the technical field of antibacterial sprays, and discloses a thrombolytic oral antibacterial spray and a preparation method thereof, wherein the formula comprises ginseng, cordyceps sinensis, saffron, honeysuckle, longan, semen allii tuberosi, aloe, pseudo-ginseng, dried ginger, astragalus and semen cuscutae, and the weight parts of the raw materials in the formula are respectively as follows: 48-50 parts of ginseng, 48-50 parts of cordyceps sinensis, 48-50 parts of saffron crocus, 100-108 parts of honeysuckle, 140-150 parts of longan, 140-150 parts of semen allii tuberosi, 95-100 parts of aloe, 95-100 parts of pseudo-ginseng, 95-100 parts of dried ginger, 95-100 parts of astragalus mongholicus and 95-100 parts of semen cuscutae, and the preparation method comprises the following steps: step one, breaking walls and powdering; step two, adding white spirit; step three, fermenting and taking liquid; step four, checking and filling; the product can be used for dissolving thrombus, reducing blood fat, preventing cerebral infarction, myocardial infarction, arteriosclerosis and hemiplegia, and can produce a plurality of active enzymes through fermentation, and compared with an oral liquid, the product has a better effect on patient parts such as sublingual.

Description

Thrombolytic oral bacteriostatic spray and preparation method thereof
Technical Field
The invention relates to the technical field of antibacterial sprays, in particular to a thrombolytic oral antibacterial spray and a preparation method thereof.
Background
Thrombolysis is the dissolution of a thrombus within a blood vessel, which is formed because of fibrinogen. The existing thrombolytic oral liquid has slow effect, so that the design of a thrombolytic oral bacteriostatic spray and a preparation method thereof are necessary.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a thrombolytic oral bacteriostatic spray and a preparation method thereof, the product generates a plurality of active enzymes through fermentation, and has quicker and better effect compared with oral liquid aiming at the patient parts such as sublingual; can be used for dissolving thrombus, reducing blood lipid, and preventing cerebral infarction, myocardial infarction, arteriosclerosis, and hemiplegia.
In order to achieve the purpose, the invention provides the following technical scheme: the thrombolytic oral bacteriostatic spray comprises ginseng, cordyceps, saffron, honeysuckle, longan, semen allii tuberosi, aloe, pseudo-ginseng, dried ginger, astragalus and semen cuscutae, and the weight parts of the raw materials in the formula are respectively as follows: 48-50 parts of ginseng, 48-50 parts of cordyceps sinensis, 48-50 parts of saffron, 100-108 parts of honeysuckle, 140-150 parts of longan, 140-150 parts of semen allii tuberosi, 95-100 parts of aloe, 95-100 parts of pseudo-ginseng, 95-100 parts of dried ginger, 95-100 parts of astragalus mongholicus, 95-100 parts of semen cuscutae and a proper amount of white spirit.
Preferably, the liquor is 60-degree pure grain liquor, and the specific raw materials are one or more of wheat millet, sorghum, corn and sweet potato.
A preparation method of a thrombolytic oral bacteriostatic spray comprises the following steps: step one, breaking walls and powdering; step two, adding white spirit; step three, fermenting and taking liquid; step four, checking and filling;
in the first step, the clean Chinese herbal medicines are selected and put into a wall breaking machine to be ground into powder at the rotating speed of 1000-; sieving, breaking cell wall, and mixing;
in the second step, the mixed medicinal powder is filled into a container, and the white spirit is poured into the container and is slowly stirred at the same time, so that the medicinal powder and the white spirit are fully mixed;
in the third step, the container is sealed, and the mixture is fermented for 49 days under the condition of cool and dry, and then the stock solution of the upper part is taken;
and in the fourth step, the mixture is put into a spraying container after being qualified.
Preferably, the mesh number of the sieve used for sieving in the step one is 50-150 meshes, so that the fineness of the medicinal powder is ensured to be uniform.
Preferably, the material of the container in the second step and the third step is 304 stainless steel, so that the stability is good.
Preferably, the volume ratio of the mixed medicinal powder to the white spirit in the second step is 1: 1.5, so that infiltration is facilitated.
Compared with the prior art, the invention provides a thrombolytic oral bacteriostatic spray and a preparation method thereof, and the thrombolytic oral bacteriostatic spray has the following beneficial effects: through fermentation after various traditional Chinese medicines are ground into powder, active ingredients of the traditional Chinese medicines are dissolved in fermentation liquor, the oral cavity bacteriostatic spray is used as an oral cavity bacteriostatic spray, thrombus can be dissolved, blood fat is reduced, cerebral infarction, myocardial infarction, arteriosclerosis and hemiplegia are prevented, and the product generates a plurality of active enzymes through fermentation, and is quicker and better compared with an oral liquid effect aiming at patient parts such as sublingual and the like.
Drawings
FIG. 1 is a flow chart of the preparation method of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
Referring to fig. 1, a thrombolytic oral bacteriostatic spray comprises ginseng, cordyceps, saffron, honeysuckle, longan, semen allii tuberosi, aloe, pseudo-ginseng, dried ginger, astragalus and semen cuscutae, wherein the weight parts of the raw materials in the formula are respectively as follows: 50 parts of ginseng, 50 parts of cordyceps, 50 parts of saffron, 108 parts of honeysuckle, 150 parts of longan, 150 parts of semen allii tuberosi, 100 parts of aloe, 100 parts of pseudo-ginseng, 100 parts of dried ginger, 100 parts of astragalus mongholicus, 100 parts of semen cuscutae and a proper amount of white spirit.
Preferably, the liquor is 60 ° pure grain liquor, and the specific raw material is sorghum.
Example two
Referring to fig. 1, a thrombolytic oral bacteriostatic spray comprises ginseng, cordyceps, saffron, honeysuckle, longan, semen allii tuberosi, aloe, pseudo-ginseng, dried ginger, astragalus and semen cuscutae, wherein the weight parts of the raw materials in the formula are respectively as follows: 50 parts of ginseng, 50 parts of cordyceps, 50 parts of saffron, 108 parts of honeysuckle, 150 parts of longan, 150 parts of semen allii tuberosi, 100 parts of aloe, 100 parts of pseudo-ginseng, 100 parts of dried ginger, 100 parts of astragalus mongholicus, 100 parts of semen cuscutae and a proper amount of white spirit.
Preferably, the liquor is 60 ° pure grain liquor, and the specific raw materials are sorghum and corn.
EXAMPLE III
Referring to fig. 1, a thrombolytic oral bacteriostatic spray comprises ginseng, cordyceps, saffron, honeysuckle, longan, semen allii tuberosi, aloe, pseudo-ginseng, dried ginger, astragalus and semen cuscutae, wherein the weight parts of the raw materials in the formula are respectively as follows: 50 parts of ginseng, 50 parts of cordyceps, 50 parts of saffron, 108 parts of honeysuckle, 150 parts of longan, 150 parts of semen allii tuberosi, 100 parts of aloe, 100 parts of pseudo-ginseng, 100 parts of dried ginger, 100 parts of astragalus mongholicus, 100 parts of semen cuscutae and a proper amount of white spirit.
Preferably, the Chinese liquor is 60 ° pure grain Chinese liquor, and the specific raw materials are semen Tritici Aestivi and jowar.
A preparation method of a thrombolytic oral bacteriostatic spray comprises the following steps: step one, breaking walls and powdering; step two, adding white spirit; step three, fermenting and taking liquid; step four, checking and filling;
in the first step, the clean Chinese herbal medicines are selected and put into a wall breaking machine to be ground into powder at the rotating speed of 1200 rpm; breaking cell wall again after sieving, mixing for use, and sieving with 100 mesh sieve;
in the second step, the mixed medicinal powder is filled into a container made of 304 stainless steel, the white spirit is poured into the container, and the mixture is slowly stirred at the same time, so that the medicinal powder and the white spirit are fully mixed, and the volume ratio of the mixed medicinal powder to the white spirit is 1: 1.5;
in the third step, the container is sealed, and the mixture is fermented for 49 days under the condition of cool and dry, and then the stock solution of the upper part is taken;
and in the fourth step, the mixture is put into a spraying container after being qualified.
In conclusion, the invention adopts high-purity grain liquor to soak various traditional Chinese medicine powder, obtains supernatant after 49 days of fermentation, and prepares the oral spray, which can dissolve thrombus, reduce blood fat, prevent cerebral infarction, myocardial infarction, arteriosclerosis and hemiplegia.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A thrombolytic oral bacteriostatic spray comprises ginseng, cordyceps, saffron, honeysuckle, longan, semen allii tuberosi, aloe, pseudo-ginseng, dried ginger, astragalus and semen cuscutae, and is characterized in that: the weight parts of the raw materials in the formula are respectively as follows: 48-50 parts of ginseng, 48-50 parts of cordyceps sinensis, 48-50 parts of saffron, 100-108 parts of honeysuckle, 140-150 parts of longan, 140-150 parts of semen allii tuberosi, 95-100 parts of aloe, 95-100 parts of pseudo-ginseng, 95-100 parts of dried ginger, 95-100 parts of astragalus mongholicus, 95-100 parts of semen cuscutae and a proper amount of white spirit.
2. The thrombolytic oral bacteriostatic spray of claim 1, wherein: the liquor is 60-degree pure grain liquor, and the specific raw materials are one or more of wheat millet, sorghum, corn and sweet potato.
3. A preparation method of a thrombolytic oral bacteriostatic spray comprises the steps of breaking cell wall and powdering; step two, adding white spirit; step three, fermenting and taking liquid; step four, checking and filling; the method is characterized in that:
in the first step, the clean Chinese herbal medicines are selected and put into a wall breaking machine to be ground into powder at the rotating speed of 1000-; sieving, breaking cell wall, and mixing;
in the second step, the mixed medicinal powder is filled into a container, and the white spirit is poured into the container and is slowly stirred at the same time, so that the medicinal powder and the white spirit are fully mixed;
in the third step, the container is sealed, and the mixture is fermented for 49 days under the condition of cool and dry, and then the stock solution of the upper part is taken;
and in the fourth step, the mixture is put into a spraying container after being qualified.
4. The method for preparing a thrombolytic oral bacteriostatic spray according to claim 3, wherein the method comprises the following steps: the mesh number of the screen used for screening in the step one is 50-150 meshes.
5. The method for preparing a thrombolytic oral bacteriostatic spray according to claim 3, wherein the method comprises the following steps: the material of the container in the second step and the third step is 304 stainless steel.
6. The method for preparing a thrombolytic oral bacteriostatic spray according to claim 3, wherein the method comprises the following steps: and in the second step, the volume ratio of the mixed medicinal powder to the white spirit is 1: 1.5.
CN202210025043.XA 2022-01-11 2022-01-11 Thrombolytic oral bacteriostatic spray and preparation method thereof Pending CN114344435A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1712026A (en) * 2004-06-22 2005-12-28 胡秀爱 Compound Chinese medicinal preparation containing Astragalus mongholicus active component
CN103948882A (en) * 2014-02-27 2014-07-30 香港嘉峰医药血栓科技开发有限公司 Traditional Chinese medicine for treating thrombus
CN108018168A (en) * 2016-10-29 2018-05-11 贵州龙里荣和酒业有限公司 One kind takes care of health white wine and preparation method thereof
CN109528881A (en) * 2019-01-07 2019-03-29 魏群 Chinese medicine composition, preparation method and applications
CN109554270A (en) * 2018-11-22 2019-04-02 福泉星合养生发展有限公司 A kind of Chinese medicinal health-care drink
CN109806379A (en) * 2019-03-22 2019-05-28 翟计山 A kind of sublingual thrombolysis oral bacteriostasis spray
CN110585363A (en) * 2019-10-24 2019-12-20 山东众健华荣生物科技有限公司 Substitutional tea with effect of reducing high blood pressure, high blood sugar and high blood lipid and preparation method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1712026A (en) * 2004-06-22 2005-12-28 胡秀爱 Compound Chinese medicinal preparation containing Astragalus mongholicus active component
CN103948882A (en) * 2014-02-27 2014-07-30 香港嘉峰医药血栓科技开发有限公司 Traditional Chinese medicine for treating thrombus
CN108018168A (en) * 2016-10-29 2018-05-11 贵州龙里荣和酒业有限公司 One kind takes care of health white wine and preparation method thereof
CN109554270A (en) * 2018-11-22 2019-04-02 福泉星合养生发展有限公司 A kind of Chinese medicinal health-care drink
CN109528881A (en) * 2019-01-07 2019-03-29 魏群 Chinese medicine composition, preparation method and applications
CN109806379A (en) * 2019-03-22 2019-05-28 翟计山 A kind of sublingual thrombolysis oral bacteriostasis spray
CN110585363A (en) * 2019-10-24 2019-12-20 山东众健华荣生物科技有限公司 Substitutional tea with effect of reducing high blood pressure, high blood sugar and high blood lipid and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李芳 等: "老年性痴呆的中药治疗及施护", 《中医药学报》 *

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