CN114288374A - Herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases - Google Patents
Herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases Download PDFInfo
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Abstract
A herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases relates to a traditional Chinese medicine formula preparation for relaxing muscles and tendons, promoting blood circulation, removing blood stasis and dredging collaterals. The herbal preparation is prepared by grinding 20-150 parts of kudzu root, 20-100 parts of ligusticum wallichii, 10-100 parts of angelica sinensis, 10-100 parts of safflower, 10-100 parts of corydalis tuber, 10-100 parts of turmeric, 15-150 parts of mistletoe, 15-150 parts of rhizoma cibotii, 10-100 parts of achyranthes root, 10-100 parts of cassia twig and 10-100 parts of white paeony root into powder to prepare paste according to the parts by weight, and treating by adopting a medicament transdermal penetration mode. The treatment result accords with the efficacies of warming channels, dredging collaterals and promoting blood circulation to remove arthralgia, takes the pathogenic factors and the vital qi into consideration, eliminates the pathogenic factors without damaging the vital qi, strengthens the vital qi without leaving the pathogenic factors, and has more obvious curative effect on various cervical and lumbar diseases.
Description
Technical Field
The invention relates to a traditional Chinese medicine formula preparation for relaxing muscles and tendons, promoting blood circulation, removing blood stasis and dredging collaterals.
Background
Cervical spondylosis and lumbar spondylosis are common diseases and frequently encountered diseases of modern middle-aged and young people and old people, the incidence rate is increased year by year, the onset age is gradually reduced, the diseases are mainly diseases which are changed into basic diseases by spinal degenerative pathology, and a series of clinical syndromes of dysfunction occur due to hyperosteogeny caused by long-term strain, or prolapse of intervertebral disc and thickening of ligament, which cause compression of nerves and spinal cords. The clinical manifestations are stiffness and pain of neck or waist and leg or pain radiating to head, shoulder, back and lower limbs, difficulty in movement, numbness and pain of extremities and spasm of limbs.
The disease belongs to the categories of lumbago and arthralgia syndrome in the traditional Chinese medicine, and the plain question and Bi Lun has the recorded expression that wind, cold and dampness are all mixed in qi and are also arthralgia syndrome. The victory of wind-qi is arthralgia-syndrome, the victory of cold-qi is arthralgia-syndrome, and the victory of damp-qi is also arthralgia-syndrome. The 'Suwen-Zhi Zhen Yao Da Lun' calls that the spasm and spasm of the neck are strong and all belong to the dampness, and the dampness and the exterior prevail. The Su Wen & Chang Ci Jie Lun states that the disease is in bones, the weight of bones is inexplicable, the bone marrow is sore and painful, and the cold qi reaches, so that the disease is called bone bi. The pathogenesis of the disease in traditional Chinese medicine is liver and kidney deficiency and malnutrition of tendons and vessels; traumatic injury, qi and blood stasis; cold-dampness invades internally and blocks the meridians.
The western medicine treatment mostly adopts anti-inflammatory symptomatic treatment, uses non-steroidal anti-inflammatory drugs to relieve inflammation and inhibit immunity, and has unstable curative effect, large side effect, high surgical treatment risk and poor tolerance of patients. The traditional Chinese medicine mainly treats cervical and lumbar diseases by traction, closure, exercise, physical therapy, traditional therapy and operative therapy. The traditional Chinese medicine shows unique advantages and obvious curative effect. Based on the basic principle of clearing and tonifying the excess and deficiency, the Chinese medicinal composition has the effects of nourishing liver and kidney, strengthening tendons and bones, promoting blood circulation by removing blood stasis, dispelling cold and removing dampness. The external traditional Chinese medicine can make the efficacy of the medicine directly reach the focus, and has the characteristics of simplicity, convenience, practicability, small side effect and the like.
Disclosure of Invention
The invention provides a formula preparation for relaxing muscles and tendons, promoting blood circulation, removing blood stasis and dredging collaterals, which is used for treating symptoms such as stiff neck or waist and leg pain caused by blood stasis blocking type cervical and lumbar diseases, pain radiating to head, shoulder, back and lower limbs, difficulty in movement, numbness and pain of extremities, spasm of limbs and the like.
A herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases is characterized in that the preparation is prepared by grinding 20-150 parts of kudzu vine root, 20-100 parts of ligusticum wallichii, 10-100 parts of angelica sinensis, 10-100 parts of safflower, 10-100 parts of corydalis tuber, 10-100 parts of turmeric, 15-150 parts of parasitic, 15-150 parts of rhizoma cibotii, 10-100 parts of achyranthes bidentata, 10-100 parts of cassia twig and 10-100 parts of white paeony root into powder according to parts by weight;
the powder is mixed into paste and then treated by adopting a mode of medicine transdermal penetration.
Modern pharmacological studies show that:
ramulus Cinnamomi contains volatile oil such as cinnamyl alcohol and cinnamaldehyde, and organic acid mainly containing cinnamic acid, and has antipyretic, analgesic, antibacterial, antiviral, blood vessel dilating, antioxidant, and diuretic effects.
The peony mainly contains peony total glycosides, and has anti-inflammatory and analgesic effects in cooperation with ramulus Cinnamomi.
The main chemical components of the kudzu root comprise isoflavone, triterpenes, saponins and the like, and the kudzu root has the pharmacological effects of relieving fever, resisting inflammation, resisting infection, reducing blood pressure, blood sugar and blood fat, improving reproductive function and the like.
The achyranthes extracting solution can improve the phagocytic capacity of cells to bacteria, expand blood vessels, improve circulation, promote the absorption of inflammatory lesions, and exert stronger anti-inflammatory and detumescent effects so as to improve the immunologic function of organisms.
The herba Taxilli contains flavone, volatile oil, vitamins, and trace elements. Researches show that the flavonoids can inhibit osteoclast differentiation and further promote bone formation, thereby playing the role of resisting osteoporosis.
The ligusticum wallichii mainly contains components such as alkaloid, organic acid, polysaccharide, volatile oil and the like, has obvious sedative and analgesic effects, and has wide pharmacological action and clinical application in the aspects of preventing and treating various diseases.
The angelica has wide pharmacological action and obvious anti-inflammatory and analgesic effects, and has obvious inhibition effects on acute capillary permeability increase, tissue edema and chronic inflammatory injury caused by various inflammatory agents.
Carthami flos has antiinflammatory, immunity inhibiting, analgesic, tranquilizing, myocardial and brain microcirculation disturbance improving, and cholesterol reducing effects.
The effective components of rhizoma corydalis are mainly alkaloid components, and have obvious effects of relieving pain and tranquilizing, and also can inhibit gastric acid secretion and improve myocardial ischemia.
The turmeric mainly contains curcumin and volatile oil, and has pharmacological effects of resisting inflammation, reducing blood lipid, resisting tumor, inhibiting angiogenesis, resisting oxidation, protecting liver, etc.
The rhizoma Cibotii has rich chemical components, and has effects of preventing and treating osteoporosis, inhibiting platelet aggregation, stopping bleeding and relieving pain, inhibiting bacteria, resisting inflammation, resisting rheumatism, protecting liver, resisting oxidation and resisting cancer.
The cervical and lumbar diseases are stiffness and pain of neck or waist and leg or pain radiating to head, shoulder, back and lower limbs, difficult movement, numbness and pain of extremities and spasm of limbs. The disease belongs to the categories of neck arthralgia, lumbago and arthralgia in traditional Chinese medicine, and is an intrinsic factor causing joint lesions due to liver and kidney deficiency, disharmony of qi and blood, wind-cold-dampness, cold-dampness obstruction of tendons and vessels and unsmooth circulation of qi and blood, which are the saying of pain caused by obstruction. Due to obstruction of the channels and vessels, the failure of qi and blood to circulate results in stagnation of blood stasis, obstruction of the channels and vessels, and further blood failing to nourish the muscles, resulting in muscular tension, soreness, numbness and difficulty in flexion and extension of the joints. When used for treating the diseases, the Chinese medicinal composition can relax muscles and tendons, promote blood circulation, remove blood stasis and dredge collaterals.
The prescription takes the root of kudzu vine and the rhizome of chuanxiong as the monarch drug, and the root of kudzu vine has sweet and pungent taste and cool property, and has the effects of promoting the production of body fluid and relaxing channels and collaterals. Chuan Xiong can activate blood and resolve stasis, promote qi circulation and alleviate pain. The angelica, the safflower, the corydalis tuber and the turmeric are used as ministerial drugs, and the effects of removing blood stasis, dredging collaterals, promoting qi circulation and relieving pain of the monarch drugs are enhanced. Because the internal causes of the disease are liver and kidney deficiency and qi and blood disharmony, the loranthus parasiticus, the cibotium barometz and the achyranthes bidentata are used for tonifying the liver and kidney and strengthening the bones and muscles; cassia twig and white peony root, radix paeoniae alba benefit qi and nourish blood and are used as adjuvant drugs together. The whole formula has the effects of relaxing muscles and tendons, promoting blood circulation, removing blood stasis and dredging collaterals.
The invention adopts a treatment mode of percutaneous permeation and absorption of the medicine, and the medicine is absorbed through the skin, thereby having the effect of whole body treatment. Different from other administration modes, the mode has unique advantages, is simple and easy to operate, can avoid the first pass effect of the liver and the damage of digestive enzymes of the gastrointestinal tract, can maintain stable and lasting medicine concentration, exerts longer medicine curative effect, and can reduce medicine toxicity and adverse reaction so as to improve the medicine utilization rate. Research on the traditional Chinese medicine transdermal agent shows that two main ways of percutaneous absorption of the medicine are as follows: through the stratum corneum and through the intercellular spaces. The Chinese medicinal components can change the arrangement configuration of lipid, improve cell permeability, increase skin temperature, and increase blood flow, thereby facilitating the penetration of medicine or nutrient through stratum corneum. By coating the affected skin, the medicine efficacy directly reaches the focus of infection to improve local microcirculation, promote local metabolism, accelerate the absorption and disappearance of inflammatory edema, relieve or eliminate local nerve and tissue compression symptoms, promote the recovery of nerve function, relieve pain symptoms and achieve the treatment effect.
91 parts of the outpatient medical records are collected for 91 diagnoses. The age is 21-60 years, six types of the blood stasis type cervical and lumbar diseases are included according to the invention, and 4 cases (4.4%) are cured in the treatment result; 16 cases (17.58%) of significant effect; 65 cases (71.42%) were effective; ineffective 6 cases (6.6%). The six types are 19 cases of cervical spondylosis respectively; 12 cases of scapulohumeral periarthritis; lumbar intervertebral disc protrusion 15 cases; 12 cases of lumbar spinal stenosis; osteoarthritis 33 cases; the judgment standard of the treatment result is as follows:
(1) evaluation of therapeutic effects on cervical spondylosis
And (3) curing: the reduction of symptoms and sign points such as pain, numbness or dizziness is more than or equal to 95 percent, and the X-ray shows that the symptoms and sign points are normal.
The effect is shown: the reduction of symptoms and sign integration such as pain, numbness or dizziness is more than or equal to 70 percent and less than 95 percent, and the X-ray shows obvious improvement.
The method has the following advantages: the reduction of symptoms and sign points such as pain, numbness or dizziness is more than or equal to 30 percent and less than 70 percent, and the X-ray shows that the disease is improved.
And (4) invalidation: the reduction of symptoms and signs such as pain, numbness or dizziness is less than 30%, and the X-ray shows no change. (2) Evaluation of therapeutic Effect on scapulohumeral periarthritis
And (3) curing: the symptoms disappear completely, and the shoulder joint movement range returns to normal.
The effect is shown: the symptom is obviously relieved, and the shoulder joint movement range is obviously improved.
The method has the following advantages: the symptoms are basically relieved, and the shoulder joint moving range is partially improved.
And (4) invalidation: all aspects were not improved compared to before treatment.
(3) Evaluation of therapeutic effects on prolapse of lumbar intervertebral disc
And (3) curing: the waist and leg pain basically disappears, the straight leg elevation test is negative, and the normal work is recovered.
The effect is shown: the pain part of the waist disappears, no obvious pressure pain point exists, the straight leg lifting test is negative, and the normal work is basically recovered.
The method has the following advantages: slight waist and leg pain, suspicious positive in the straight leg lifting test and partial recovery work.
And (4) invalidation: the pain in the waist and legs is not improved, the straight leg elevation test is positive, and the operation cannot be performed adequately.
(4) Evaluation of therapeutic Effect of lumbar spinal stenosis
And (3) curing: the pain in the waist and legs basically disappears, and the original work is recovered without intermittent lameness.
The effect is shown: the pain in the waist and legs disappears, and the patient basically recovers to normal after walking for more than 1000m continuously.
The method has the following advantages: there is mild pain in the waist and legs, 400m walking, and the patient should bend down to rest, and partially recover.
And (4) invalidation: pain in the waist and legs, no improvement and no continuous work.
(5) Evaluation of osteoarthritis efficacy
And (3) clinical control: the symptoms such as pain disappear, the joint moves normally, the integral is reduced by more than or equal to 95 percent, and the X-ray shows that the joint is normal.
The effect is shown: the symptoms such as pain and the like disappear, the joint movement is not limited, and the integral is reduced by more than or equal to 70 percent and less than 95 percent. X-rays showed a clear improvement.
The method has the following advantages: the symptoms such as pain and the like are basically eliminated, the joint movement is slightly limited, the integral is reduced by more than or equal to 30 percent and less than 70 percent, and the X-ray shows that the disease is improved.
And (4) invalidation: the symptoms such as pain and the like and joint movement are not obviously improved, the integral is reduced by less than 30 percent, and the X-ray is not changed.
The treatment result accords with the efficacies of warming channels, dredging collaterals and promoting blood circulation to remove arthralgia, takes the pathogenic factors and the vital qi into consideration, eliminates the pathogenic factors without damaging the vital qi, strengthens the vital qi without leaving the pathogenic factors, and has more obvious curative effect on various cervical and lumbar diseases.
Detailed Description
Example 1: dong some, woman, 32, 2 months and 16 days of initial diagnosis in 2021, mainly complaining of neck and neck pain with dizziness for 1 year. Stabbing pain in the neck, shoulder and upper limbs, fixed pain with numbness of limbs, marked lumbago, radiation to lower limbs, dark tongue, and wiry pulse.
The current medical history: the patient suffers from stiff and stabbing pain of neck and neck after tiredness 1 year ago, accompanied by numbness of limbs, and progressive exacerbation, and the symptoms are as follows: stiffness and stabbing pain of neck and neck, numbness of limbs, no nausea and vomiting, no obstruction of limbs, and incapability of standing and walking. Poor sleep, the second time, purple-dark tongue and deep and unsmooth pulse.
Diagnosing the cervical spondylosis with the syndrome of blood stasis.
The treatment adopts 20g of kudzuvine root, 20g of Szechuan lovage rhizome, 20g of Chinese angelica, 10g of safflower, 15g of corydalis tuber, 15g of turmeric, 15g of Chinese taxillus twig, 15g of east Asian tree fern rhizome, 15g of twotooth achyranthes root, 20g of cassia twig and 10g of white paeony root. Grinding into powder with a traditional Chinese medicine grinder, mixing thoroughly, pouring into a container, adding appropriate amount of warm boiled water, stirring well to obtain paste, applying on neck skin surface when the temperature is suitable, and baking with TDP lamp for 30 min once a day for 7 times as a treatment course.
After repeated diagnosis in 2021, 2 months and 22 days, the stiffness and pain of neck and neck of the patient are obviously relieved and the dizziness is obviously improved after seven treatments. Red tongue with thin and white coating and slow pulse. The diagnosis, prescription and treatment are the same as before. The patient can return to visit after 1 month, and the neck of the patient can move freely without special discomfort.
Example 2: for the rest, women are 42 years old, and the initial diagnosis is carried out in 2021 year, 2 month and 20 days, and the pain and discomfort of the waist and the legs are mainly complained for 5 years, and the pain and the discomfort are aggravated for more than 5 days.
The current medical history: pain in waist and legs did not appear obvious induction 5 years ago, pain and numbness of both lower limbs occurred after irradiation, lumbar X-ray shows hyperosteogeny of lumbar vertebra, slight protrusion of 3, 4 and 5 waist, and 2. degenerative change of lumbar vertebra. The patients are treated by oral medication after visiting a local private clinic without systematic diagnosis and treatment, the pain is aggravated before 5 days, the pain is like acupuncture, the patients cannot turn to the side, the tongue is dark purple, and the pulse is unsmooth.
The lumbago caused by blood stasis can be diagnosed.
The treatment adopts 20g of kudzuvine root, 20g of Szechuan lovage rhizome, 20g of Chinese angelica, 10g of safflower, 15g of corydalis tuber, 15g of turmeric, 15g of Chinese taxillus twig, 15g of east Asian tree fern rhizome, 15g of twotooth achyranthes root, 20g of cassia twig and 10g of white paeony root. Grinding into powder with a traditional Chinese medicine grinder, mixing thoroughly, pouring into a container, adding appropriate amount of warm boiled water, stirring well to obtain paste, applying on waist and leg skin surface when the temperature is suitable, and baking with TDP lamp for 30 min once a day for 7 times as a treatment course.
The patient is treated with the second treatment of 26 days at 2 months in 2021, the pain in the waist of the patient is obviously improved, and the patient can move. A red tongue with a thin and white coating and a wiry pulse. The diagnosis, prescription and treatment are the same as before. The patient visits after 1 month, and has no pain, no special discomfort and no movement.
Example 3: li Shi, female, 45 years old, first diagnosis in 2021, 2 months and 15 days, complaining of neck and neck pain with difficulty in movement for 3 days.
The current medical history: the patient suffered from neck pain, difficulty in moving, aggravated pain after moving, neck muscle tension, illness, poor spirit, poor sleep, dark tongue, thin and white fur and deep and unsmooth pulse due to improper sleeping posture 3 days ago.
Diagnosing the stiff neck with blood stasis.
The treatment adopts 20g of kudzuvine root, 20g of Szechuan lovage rhizome, 20g of Chinese angelica, 10g of safflower, 15g of corydalis tuber, 15g of turmeric, 15g of Chinese taxillus twig, 15g of east Asian tree fern rhizome, 15g of twotooth achyranthes root, 20g of cassia twig and 10g of white paeony root. Grinding into powder with a traditional Chinese medicine grinder, mixing thoroughly, pouring into a container, adding appropriate amount of warm boiled water, stirring well to obtain paste, applying on neck skin surface when the temperature is suitable, and baking with TDP lamp for 30 min once a day for 7 times as a treatment course.
The patient is diagnosed twice at 2 months and 16 days in 2021, and the neck pain of the patient is relieved after the treatment of yesterday, the tongue is dark, the tongue coating is thin and white, and the pulse condition is deep and unsmooth. The diagnosis, prescription and treatment are the same as before.
Three diagnoses in 2 months and 17 days in 2021, the third treatment of the patient shows that the neck and neck pain of the patient is obviously improved, the tongue is red, the coating is thin and white, and the pulse is deep. The diagnosis, prescription and treatment are the same as before. The patient can return to visit after 1 month, and the neck of the patient can move freely without special discomfort.
Claims (1)
1. A herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases is characterized in that the preparation is prepared by grinding 20-150 parts of kudzu vine root, 20-100 parts of ligusticum wallichii, 10-100 parts of angelica sinensis, 10-100 parts of safflower, 10-100 parts of corydalis tuber, 10-100 parts of turmeric, 15-150 parts of parasitic, 15-150 parts of rhizoma cibotii, 10-100 parts of achyranthes bidentata, 10-100 parts of cassia twig and 10-100 parts of white paeony root into powder according to parts by weight; the powder is mixed into paste and then treated by adopting a mode of medicine transdermal penetration.
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| CN102058681A (en) * | 2009-11-17 | 2011-05-18 | 关屹明 | Traditional Chinese medicine for treating protrusion of lumbar vertebral disc and waist and leg pain and preparation method thereof |
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| CN105853668A (en) * | 2016-05-20 | 2016-08-17 | 万宣 | Medicament for treating lumbar disc herniation, osteoporosis and cervical spondylosis |
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2021
- 2021-12-28 CN CN202111618810.XA patent/CN114288374A/en active Pending
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| CN102058681A (en) * | 2009-11-17 | 2011-05-18 | 关屹明 | Traditional Chinese medicine for treating protrusion of lumbar vertebral disc and waist and leg pain and preparation method thereof |
| CN105079682A (en) * | 2014-05-07 | 2015-11-25 | 杨富 | Medicinal liquor for treating cervical spondylosis |
| CN104815111A (en) * | 2015-04-10 | 2015-08-05 | 栾尊一 | Traditional Chinese medicine composition for treating lumbar disc herniation, cervical spondylosi and osteoproliferation |
| CN105853668A (en) * | 2016-05-20 | 2016-08-17 | 万宣 | Medicament for treating lumbar disc herniation, osteoporosis and cervical spondylosis |
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