CN102058681A - Traditional Chinese medicine for treating protrusion of lumbar vertebral disc and waist and leg pain and preparation method thereof - Google Patents
Traditional Chinese medicine for treating protrusion of lumbar vertebral disc and waist and leg pain and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating protrusion of lumbar vertebral disc and waist and leg pain and a preparation method thereof. The technical scheme is that: the traditional Chinese medicine is prepared from pseudoginseng root, white paeony root, Chinese angelica, cassia twig, rhizoma corydalis, twotooth achyranthes root, East Asian tree fern rhizome, heracleum and red flower. The preparation method comprises the following steps of: crushing the pseudoginseng root into fine powder with the granularity of 120 meshes; crushing the Chinese angelica, the cassia twig and the rhizoma corydalis into coarse powder with the granularity of 10 meshes, soaking in 60 percent ethanol in an amount which is five times weight of the powder for 24 hours, heating and refluxing for 3 hours, adding 60 percent ethanol in an amount which is two times weight of the powder, heating and refluxing for 2 hours, mixing the extracting solution in two times and concentrating into thick paste; decocting the white paeony root, the East Asian tree fern rhizome, the heracleum and the red flower in water for three times, namely adding water in an amount which is five times weight of the materials to decoct for 3 hours for the first time, adding water in an amount which is three times weight of the material to decoct for 2 hours for the second time and adding water in an amount which is three times weight of the materials to decoct for 1.5 hours for the third time, mixing the filtrate in three times and concentrating into thick paste; mixing the thick paste, adding the fine pseudoginseng root powder with the granularity of 120 meshes and medicinal auxiliary materials, uniformly mixing, drying, crushing and filling in capsules. The medicine has an obvious curative effect of treating the lumbar vertebral disc and waist and leg pain.
Description
Technical field
The present invention relates to the field of Chinese medicines, relate to a kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia particularly.
Background technology
Prolapse of lumbar intervertebral disc and lumbago and skelalgia are a kind of common clinicals, at present have the people of 15%-20% to suffer from this disease in China's physical labourer, are most commonly in 25-50 year person between twenty and fifty.Its sickness rate height has a strong impact on people's working and learning.The method of treatment prolapse of lumbar intervertebral disc mainly contains expectant treatment and operative treatment at present.The expenses of surgical treatment height, the operation subject range is limited, and leaves sequela easily.And expectant treatment is mainly: absolute bed rest; Continuous traction; Physical therapy, massage and massage.Traction, massage therapies etc. are the expense height not only, and the patient is walked about to make troubles.
Summary of the invention
In order to overcome the above problems, the purpose of this invention is to provide a kind of taking convenience, the treatment prolapse of lumbar intervertebral disc evident in efficacy and the Chinese medicine of lumbago and skelalgia.
Another object of the present invention provides a kind of preparation method of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia.
To achieve these goals, the technical solution used in the present invention is: a kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia, make by following raw material medicaments in part by weight proportioning:
15～20 parts of Radix Notoginseng, 35～40 parts of the Radix Paeoniae Albas,
20～25 parts of Radix Angelicae Sinensis, 20～25 parts of Ramulus Cinnamomi,
60～70 parts of Rhizoma Corydalis, 20～25 parts of Radix Achyranthis Bidentataes,
20～25 parts of Rhizoma Cibotii, 20～25 parts of Radix Angelicae Pubescentiss,
10～15 parts on Flos Carthami.
The above-mentioned treatment prolapse of lumbar intervertebral disc and the preparation method of Chinese medicine of lumbago and skelalgia comprise the steps:
1) by above-mentioned weight portion proportion ingredient;
2) it is standby Radix Notoginseng powder to be broken into 120 order fine powders;
3) Radix Angelicae Sinensis, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Angelicae Pubescentis are ground into 10 order coarse powder, 60% soak with ethanol of usefulness quintuple 24 hours, reflux 3 hours is collected extracting solution; 60% alcohol heating reflux 2 hours that adds qdx is again collected extracting solution; Merge secondary raffinate, extracting solution is condensed into thick paste;
4) Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Rhizoma Cibotii and Flos Carthami decoct with water three times, add the quintuple decocting for the first time and boil 3 hours, filter; For the second time add the triplication decocting and boiled 2 hours, filter; Add the triplication decocting for the third time and boiled 1.5 hours, filter; Merge three times filtrate, filtrate is condensed into thick paste;
5) with the 3rd) and the 4th) thick paste that makes of step merges, and adds 120 order Radix Notoginseng fine powder and pharmaceutic adjuvants, mixing, filled capsules is pulverized in oven dry.
Pharmaceutic adjuvant (pharmaceutical excipients) is meant when preparation prescription designs, and adds the general designation of all the medicinal materials except that principal agent in the prescription for mouldability, effectiveness, stability, the safety that solves preparation.Inventive point of the present invention is to select Six-element Chinese medicine from numerous Chinese medicine, and the science compatibility is to reach the purpose of treatment.The interpolation of excipient substance is to be convenient to granulate, molding, therefore, and can be according to actual preparation, pharmaceutic adjuvant and consumption thereof that screening is suitable, this is conventional knowledge for a person skilled in the art.Pharmaceutic adjuvant commonly used has: starch, dextrin, lactose, gelatin, ethanol, glycerol, chitosan, vaseline, propylene glycol, magnesium stearate or microcrystalline Cellulose or the like.
The pharmacology of the crude drug that the present invention adopts, the property of medicine is as follows:
Radix Notoginseng: [meridian distribution of property and flavor] sweet in the mouth; Little hardship; Property wets; Return liver; Stomach; The heart; Lung; Large intestine channel; [function cures mainly] hemostasis; Blood looses; Analgesic therapy.Main falling pounces on congestive edema, thoracic obstruction angor, lump in the abdomen; The blood stasis amenorrhea; Dysmenorrhea; The cloudy stomachache of the stasis of blood in puerperal; Sore, carbuncle and painful swelling.
The Radix Paeoniae Alba: [meridian distribution of property and flavor] is bitter, sour, is slightly cold.Return liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.It is dizzy to be used to have a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Radix Angelicae Sinensis: [meridian distribution of property and flavor] is sweet, hot, temperature.Return liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.Be used for the amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Ramulus Cinnamomi: [meridian distribution of property and flavor] is hot, sweet, temperature.GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Rhizoma Corydalis: [meridian distribution of property and flavor] is hot, bitter, temperature.Return liver, spleen channel.[function cures mainly] invigorates blood circulation, promoting the circulation of QI, pain relieving.Be used for the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Radix Achyranthis Bidentatae: [meridian distribution of property and flavor] is bitter, sour, and be flat.Return liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.Be used for soreness of waist and knee joint, muscles and bones is unable, amenorrhea and mass in the abdomen, dizziness due to hyperactivity of liver-YANG.
Rhizoma Cibotii: [meridian distribution of property and flavor] is bitter, sweet, temperature.Return liver, kidney channel.[function cures mainly] invigorating the liver and kidney, strong spinal column, wind-damp dispelling.Be used for soreness of the waist and knees, weakness of the lower extremities, rheumatic arthralgia.
Radix Angelicae Pubescentis: [meridian distribution of property and flavor] is hot, bitter, tepor.Return kidney, urinary bladder channel.[function cures mainly] expelling wind and removing dampness, numbness relieving and pain relieving.Be used for anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.
Flos Carthami: [meridian distribution of property and flavor] suffering, temperature.GUIXIN, Liver Channel.[function cures mainly] promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, the not all right ， mass in the abdomen of lochia mass in the abdomen, injury from falling down, skin infection swells and ache.
The present invention is as follows to treatment prolapse of lumbar intervertebral disc and lumbago and skelalgia patient's treatment clinical observation:
(1) physical data:
Prolapse of lumbar intervertebral disc: 206 routine medical histories 8～15 years.
Lumbago and skelalgia: 286 routine medical histories 5～15 years.
(2) Therapeutic Method
Get the capsule that makes among the embodiment 1.
Instructions of taking: take twice every day, each 3,30 is a course of treatment.Take two courses of treatment.
(3) efficacy assessment standard
Prolapse of lumbar intervertebral disc
Cure: bony union, knee joint are stretched and are bent normally, and movable no pain is recovered former work.
Effectively: bony union, knee sprung reach 90 the degree, knee joint have shakiness or the time pain is arranged, can recover former work.
Invalid: the bone malformation healing, knee sprung is less than 90 degree, and knee joint often has pain, can not adapt to physical work.Lumbago and skelalgia
Cure: knee joint is stretched and is bent normally, and movable no pain is recovered former work.
Effectively: knee sprung reach 90 the degree, knee joint have shakiness or the time pain is arranged, can recover former work.
Invalid: knee sprung is less than 90 degree, and knee joint often has pain, can not adapt to physical work.
(4) therapeutic outcome (seeing Table 1)
Table 1 is the curative effect clinical observation after treating
The invention has the beneficial effects as follows: the present invention is guidance with the theory of Chinese medical science, and the science compatibility with nine flavor Chinese medicine synergism, has tangible curative effect to prolapse of lumbar intervertebral disc and lumbago and skelalgia.By clinical observation, prolapse of lumbar intervertebral disc patient cure rate is reached 46.6%, total effective rate is 94.7%; Lumbago and skelalgia patient cure rate is reached 35.0%, and total effective rate is 97.3%.
The specific embodiment:
Embodiment 1
A kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia, make by following crude drug:
Radix Notoginseng 16.83kg, Radix Paeoniae Alba 36.70kg,
Radix Angelicae Sinensis 23.70kg, Ramulus Cinnamomi 23.30kg,
Rhizoma Corydalis 66.80kg, Radix Achyranthis Bidentatae 23.30kg,
Rhizoma Cibotii 23.30kg, Radix Angelicae Pubescentis 23.30kg,
Flos Carthami 12.0kg.
Preparation method is as follows:
1) by the said ratio batching;
2) it is standby Radix Notoginseng powder to be broken into 120 order fine powders;
3) Radix Angelicae Sinensis, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Angelicae Pubescentis are ground into 10 order coarse powder, 60% soak with ethanol of usefulness quintuple 24 hours, reflux 3 hours is collected extracting solution; 60% alcohol heating reflux 2 hours that adds qdx is again collected extracting solution; Merge secondary raffinate, extracting solution is condensed into thick paste;
4) Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Rhizoma Cibotii and Flos Carthami decoct with water three times, add the quintuple decocting for the first time and boil 3 hours, filter; For the second time add the triplication decocting and boiled 2 hours, filter; Add the triplication decocting for the third time and boiled 1.5 hours, filter; Merge three times filtrate, filtrate is condensed into thick paste;
5) with the 3rd) and the 4th) thick paste that makes of step merges, and adds 120 order Radix Notoginseng fine powders and 4kg pharmaceutic adjuvant starch, mixing is put drying in oven, pulverizes 20 mesh sieves then, filled capsules.Specification is the 0.42g/ grain.
Embodiment 2
A kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia, make by following crude drug:
Radix Notoginseng 18.6kg, Radix Paeoniae Alba 35.7kg,
Radix Angelicae Sinensis 21.3kg, Ramulus Cinnamomi 23.8kg,
Rhizoma Corydalis 61.3kg, Radix Achyranthis Bidentatae 24.6kg,
Rhizoma Cibotii 22.1kg, Radix Angelicae Pubescentis 21.2kg,
Flos Carthami 10.9kg.
Preparation method is as follows:
1) by above-mentioned proportion ingredient;
2) it is standby Radix Notoginseng powder to be broken into 120 order fine powders;
3) Radix Angelicae Sinensis, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Angelicae Pubescentis are ground into 10 order coarse powder, 60% soak with ethanol of usefulness quintuple 24 hours, reflux 3 hours is collected extracting solution; 60% alcohol heating reflux 2 hours that adds qdx is again collected extracting solution; Merge secondary raffinate, extracting solution is condensed into thick paste;
4) Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Rhizoma Cibotii and Flos Carthami decoct with water three times, add the quintuple decocting for the first time and boil 3 hours, filter; For the second time add the triplication decocting and boiled 2 hours, filter; Add the triplication decocting for the third time and boiled 1.5 hours, filter; Merge three times filtrate, filtrate is condensed into thick paste;
5) with the 3rd) and the 4th) thick paste that makes of step merges, and adds 120 order Radix Notoginseng fine powder and pharmaceutic adjuvants, mixing, filled capsules is pulverized in oven dry.Specification is the 0.4g/ grain.
Embodiment 3
A kind of Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia, make by following crude drug:
Radix Notoginseng 15.6kg, Radix Paeoniae Alba 39.7kg,
Radix Angelicae Sinensis 24.5kg, Ramulus Cinnamomi 20.6kg,
Rhizoma Corydalis 68.9kg, Radix Achyranthis Bidentatae 21.3kg,
Rhizoma Cibotii 24.6kg, Radix Angelicae Pubescentis 24.3kg,
Flos Carthami 11.1kg.
Preparation method is as follows:
1) by above-mentioned weight portion proportion ingredient;
2) it is standby Radix Notoginseng powder to be broken into 120 order fine powders;
3) Radix Angelicae Sinensis, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Angelicae Pubescentis are ground into 10 order coarse powder, 60% soak with ethanol of usefulness quintuple 24 hours, reflux 3 hours is collected extracting solution; 60% alcohol heating reflux 2 hours that adds qdx is again collected extracting solution; Merge secondary raffinate, extracting solution is condensed into thick paste;
4) Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Rhizoma Cibotii and Flos Carthami decoct with water three times, add the quintuple decocting for the first time and boil 3 hours, filter; For the second time add the triplication decocting and boiled 2 hours, filter; Add the triplication decocting for the third time and boiled 1.5 hours, filter; Merge three times filtrate, filtrate is condensed into thick paste;
5) with the 3rd) and the 4th) thick paste that makes of step merges, and adds 120 order Radix Notoginseng fine powder and pharmaceutic adjuvants, mixing, filled capsules is pulverized in oven dry.Specification is the 0.45g/ grain.
Claims (2)
1. Chinese medicine for the treatment of prolapse of lumbar intervertebral disc and lumbago and skelalgia is characterized in that being made by following raw material medicaments in part by weight proportioning:
15～20 parts of Radix Notoginseng, 35～40 parts of the Radix Paeoniae Albas,
20～25 parts of Radix Angelicae Sinensis, 20～25 parts of Ramulus Cinnamomi,
60～70 parts of Rhizoma Corydalis, 20～25 parts of Radix Achyranthis Bidentataes,
20～25 parts of Rhizoma Cibotii, 20～25 parts of Radix Angelicae Pubescentiss,
10～15 parts on Flos Carthami.
2. the preparation method of Chinese medicine of described treatment prolapse of lumbar intervertebral disc of claim 1 and lumbago and skelalgia is characterized in that comprising the steps:
1) by the described weight portion proportion ingredient of claim 1;
2) it is standby Radix Notoginseng powder to be broken into 120 order fine powders;
3) Radix Angelicae Sinensis, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Angelicae Pubescentis are ground into 10 order coarse powder, 60% soak with ethanol of usefulness quintuple 24 hours, reflux 3 hours is collected extracting solution; 60% alcohol heating reflux 2 hours that adds qdx is again collected extracting solution; Merge secondary raffinate, extracting solution is condensed into thick paste;
4) Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Rhizoma Cibotii and Flos Carthami decoct with water three times, add the quintuple decocting for the first time and boil 3 hours, filter; For the second time add the triplication decocting and boiled 2 hours, filter; Add the triplication decocting for the third time and boiled 1.5 hours, filter; Merge three times filtrate, filtrate is condensed into thick paste;
5) with the 3rd) and the 4th) thick paste that makes of step merges, and adds 120 order Radix Notoginseng fine powder and pharmaceutic adjuvants, mixing, filled capsules is pulverized in oven dry.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582640A (en) * | 2017-09-18 | 2018-01-16 | 林力 | A kind of protrusion of lumber intervertebral disc thermal pack Chinese medicine preparation |
| CN114288374A (en) * | 2021-12-28 | 2022-04-08 | 云南琼月企业管理有限公司 | Herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases |
-
2009
- 2009-11-17 CN CN2009102199502A patent/CN102058681A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582640A (en) * | 2017-09-18 | 2018-01-16 | 林力 | A kind of protrusion of lumber intervertebral disc thermal pack Chinese medicine preparation |
| CN114288374A (en) * | 2021-12-28 | 2022-04-08 | 云南琼月企业管理有限公司 | Herbaceous plant preparation for treating blood stasis type cervical and lumbar diseases |
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