CN114287547A - Acne-removing and whitening beverage and preparation method thereof - Google Patents
Acne-removing and whitening beverage and preparation method thereof Download PDFInfo
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Abstract
The application relates to an acne-removing and whitening beverage and a preparation method thereof. The acne-removing whitening beverage comprises the following components: 18-45 parts of pomegranate fruit powder, 11-25 parts of saussurea involucrate culture, 6-15 parts of grape seed extract and 2-6.5 parts of hydrolyzed fish collagen. The acne-removing and whitening beverage can remarkably improve the acne-removing and whitening effects, and has the advantages of no side effect, high absorptivity, good portability and high market acceptance.
Description
The technical field is as follows:
the application belongs to the field of food and beverage, and particularly relates to an acne-removing and whitening beverage and a preparation method thereof.
Background art:
acne is also called as whelk, is the most common chronic inflammatory pilosebaceous sebaceous gland disease in dermatology, has the morbidity rate of about 80 percent in young and young people and the morbidity rate of adults of 20 to 30 years old up to 64 percent, is clinically represented by comedo, papule, pustule, cyst or nodule on the face and the chest and back, can leave pigment, deposition or scar after repeated attack, and can influence the physiology, psychology, social interaction and the like of patients. Acne occurs in close relation to factors such as hyperseborrhea, blockage of pilosebaceous ducts, microbial infection and inflammatory reactions. After adolescence, the level of androgen, particularly testosterone, in a human body is rapidly increased, the development of sebaceous glands is promoted, and a large amount of sebum is produced. If the grease can not be discharged in time to block pores, the anaerobic bacterium propionibacterium acnes can be greatly proliferated to destroy epidermal cells to trigger inflammatory reaction.
From ancient times to the present, "white to beautiful" is the mainstream aesthetic in our country, and it is because of such traditional beauty concepts that the pursuit of whitening by asian women has never been stopped, but the skin color of each person is determined by the melanin content contained in the skin. Melanin is produced in melanocytes, and is a protein present in the basal layer of the skin of everyone. The irradiation of ultraviolet rays can change melanin to generate a substance for protecting skin, and then the melanin moves to the skin epidermal layer through cell metabolism layer by layer, so that skin problems such as color spots, uneven skin color and the like are caused on the skin.
In recent years, with the continuous improvement of living standard and consumption level, people pursue self image more and more, at present, a mode of combining external use and oral medicine is mostly adopted aiming at acne removal, and the external use of retinoic acid, benzoyl peroxide and other antibacterial medicines can improve the keratosis of the pilosebaceous canal, has the functions of acne dissolving, antibacterial and anti-inflammatory, but the external use medicine has certain irritation, and can cause adverse reactions such as skin redness, desquamation and the like. The oral medicines mainly comprise isotretinoin, antibacterial drugs and hormone drugs, and the three drugs have different degrees of influence on human bodies, for example, blood fat and liver functions need to be monitored when the isotretinoin is taken, and patients in the childbearing age need to pay attention to contraception during taking and within 3 months after stopping taking the medicines. Most of the whitening products on the market are external cosmetics with good and uneven quality, and the sampling inspection results of food and drug administration in China show that many whitening products contain stimulating components, and some unqualified merchants illegally add forbidden raw materials in the products to achieve the expected whitening effect, which undoubtedly causes great harm to the health of consumers.
Most of the currently known products with the acne removing and whitening effects are creams for external use, creams for external use and medicines for internal use, and are limited by a plurality of conditions on the side effects, portability and absorption effect of the medicines, so that a beverage with the acne removing and whitening effects, no side effects, good portability and high absorption efficiency needs to be developed.
The invention content is as follows:
aiming at the defects in the prior art, one object of the application is to provide the acne-removing and whitening beverage. The acne-removing whitening beverage is prepared from pomegranate fruit powder, saussurea involucrate culture, grape seed extract, hydrolyzed fish collagen and the like serving as main raw materials, can be prepared into a ready-to-drink beverage, can obviously improve the acne-removing whitening effect, and has the advantages of no side effect, high absorptivity, good portability and high market acceptance degree.
Another object of the application is to provide a preparation method of the acne-removing and whitening beverage. The preparation method is simple and quick, and the beverage with good acne removing and whitening effects can be provided.
In order to achieve the above object, in a first aspect, the present application provides an acne removing and whitening beverage, which comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage further comprises:
28-31 parts of vitamin C.
With reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage further comprises a flavoring agent and a flavoring essence.
Further, in one possible embodiment, the flavoring agent comprises:
200-300 parts by weight of white granulated sugar,
0.5 to 1.0 part by weight of sucralose, and
100-130 parts by weight of anhydrous citric acid.
Further, in a possible embodiment, the amount of the flavoring essence is 15-60 parts by weight.
With reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage further comprises:
0.02-0.04 parts by weight of naringin, and
0.02-0.04 parts by weight of rhoifolin.
In a possible embodiment, in combination with the first aspect, the acne removing and whitening beverage further comprises 345 to 590 parts by weight of water, preferably 390 to 410 parts by weight of water.
In a second aspect, the application provides a preparation method of the acne removing and whitening beverage, which comprises the following steps:
dissolving the above components in water, mixing, and sterilizing.
In combination with the second aspect, in one possible embodiment, the preparation method includes:
respectively dispersing pomegranate fruit powder, saussurea involucrate culture, grape seed extract, hydrolyzed fish collagen and white granulated sugar in water, mixing, heating to 80-85 ℃ for full dissolution, then cooling to 30-35 ℃, adding other components, heating to 80-85 ℃, preserving heat for 10-15 min, and sterilizing.
In combination with the second aspect, in one possible embodiment, the white granulated sugar is dissolved with hot water at 45 ℃ to 55 ℃.
In combination with the second aspect, in one possible embodiment, the pomegranate fruit powder, the snow lotus culture, the grape seed extract and the hydrolyzed fish collagen are each dispersed in water and then filtered using an 80-mesh filter.
With reference to the second aspect, in one possible embodiment, the preparation method further includes: dissolving at least part of the other components except water in water to obtain aqueous solution.
In a possible embodiment, in combination with the second aspect, the sterilization is heating at 115 ℃ for 30 seconds.
According to the technical scheme provided by the application, compared with the prior art, the method at least comprises the following beneficial effects:
the acne-removing whitening beverage can remarkably improve the acne-removing whitening effect, and has the advantages of no side effect, high absorptivity, good portability and high market acceptance degree.
In addition, the preparation method is simple and rapid, and the beverage with good acne removing and whitening effects can be provided.
Detailed Description
In order that those skilled in the art will be able to more clearly understand the present application, the present application will be described in detail below with reference to examples. Before the description is given, it should be understood that the terms used in the present specification and the appended claims should not be construed as limited to general and dictionary meanings, but interpreted based on the meanings and concepts corresponding to technical aspects of the present application on the basis of the principle that the inventor is allowed to define terms appropriately for the best explanation. Accordingly, the description proposed herein is just a preferable example for the purpose of illustrations only, not intended to limit the scope of the application, so it should be understood that other equivalents and modifications could be made thereto without departing from the spirit and scope of the application, and the scope of the application claims should be determined only by the claims. Unless otherwise specified, reagents and equipment used in the following examples are commercially available products.
The method is realized by the following technical scheme:
in a first aspect, the application provides an acne-removing and whitening beverage, which comprises the following components:
in the application, the acne-removing and whitening beverage is prepared by taking pomegranate fruit powder, saussurea involucrate culture, grape pip extract and hydrolyzed fish collagen as main raw materials to prepare a ready-to-drink beverage, and the problems of large side effect, low absorption rate and inconvenience in carrying of other products are solved. Wherein
The pomegranate fruit powder contains 30-50% of polyphenol, mainly comprises flavonoids, tannins, ellagic acid, anthocyanidin and the like, wherein the punicalagin content can reach 15%. Punicalagin is a hydrolyzable tannin mainly existing in pomegranate peel, contains a plurality of phenolic hydroxyl groups in the structure, has various physiological activities of tumor inhibition, antibiosis, antiphlogosis, antioxidation and the like, and has wide development prospects in the fields of medical treatment, health care, functional foods and cosmetics. The punicalagin has strong DPPH free radical scavenging capacity, superoxide free radical scavenging capacity and anti-lipid peroxidation activity, realizes the anti-lipid peroxidation activity by scavenging hydrogen peroxide free radicals to realize chain termination reaction, and realizes the antioxidation by losing electrons to the free radicals. Related researches show that compared with other purified compounds, the biological activities of the pomegranate juice and the pomegranate total tannin prove that different compounds can interact to generate a synergistic effect, so that the biological activity of the pomegranate juice and the pomegranate total tannin generated by the synergistic effect is higher than that of other polyphenol compounds compared with the pure punicalagin. Punicalagin is hydrolyzed in intestinal tract for several hours to become ellagic acid, which is mainly accumulated in epithelial cells of intestinal tract and also partially accumulated in blood, lung and liver. Ellagic acid also has anticancer and antifungal effects in vivo, and can prevent the start of G-1 stage, thereby inducing apoptosis of tumor cells, but has no effect on normal cells. In addition, the pomegranate fruit powder preferably contains 5 to 15 mass percent of punicalagin, and more preferably 10.5 mass percent of punicalagin.
The saussurea involucrate culture is derived from callus of wild saussurea involucrate, is plant cell tissue of the saussurea involucrate obtained by a bioengineering technical means, is 100 percent of natural food material and has no side effect. The beverage contains a plurality of effective components such as flavone, polysaccharide, chlorogenic acid, syringin, trace elements, terpenes and the like, and has obvious effects on eliminating inflammation, blocking ultraviolet rays, resisting oxidation and delaying senescence. Research shows that the saussurea involucrate culture has obvious antioxidant activity when the content reaches 0.01%.
The grape seed extract contains rich procyanidin, and is popular among people due to the advantages of available rich resources, obvious treatment effect, small drug side effect and the like. Procyanidine is a bioflavonoid with a special molecular structure, and is internationally recognized as one of the most effective natural antioxidants for removing free radicals contained in human bodies. The existing research shows that the procyanidine in the grape seed extract has strong oxidation resistance, free radical removal capacity, human microcirculation improvement, mutation resistance, fatigue resistance, mutation resistance, tumor resistance, inflammation resistance, aging delay and other effects. The clinical experiment result shows that the grape seed extract procyanidin has the treatment effect on various diseases. At present, the grape seed extract is approved as a food raw material by the Ministry of health of China.
The hydrolyzed collagen is a product generated by collagen after enzymolysis, has the nutritional and physiological functions of resisting aging, promoting skin collagen metabolism, promoting bone joint health, inhibiting blood pressure rise, protecting gastric mucosa, resisting ulcer and the like, and has huge application prospect in the fields of food, cosmetics, medicines and the like.
In the present application, according to one possible embodiment, the pomegranate fruit powder may be included in an amount of 18 to 45 parts by weight, for example, 18 parts by weight, 19 parts by weight, 20 parts by weight, 21 parts by weight, 22 parts by weight, 23 parts by weight, 24 parts by weight, 25 parts by weight, 26 parts by weight, 27 parts by weight, 28 parts by weight, 29 parts by weight, 30 parts by weight, 31 parts by weight, 32 parts by weight, 33 parts by weight, 34 parts by weight, 35 parts by weight, 36 parts by weight, 37 parts by weight, 38 parts by weight, 39 parts by weight, 40 parts by weight, 41 parts by weight, 42 parts by weight, 43 parts by weight, 44 parts by weight, or 45 parts by weight, or other specific values within the range; the saussurea involucrate culture may be contained in an amount of 11 to 25 parts by weight, for example, 11 parts by weight, 12 parts by weight, 13 parts by weight, 14 parts by weight, 15 parts by weight, 16 parts by weight, 17 parts by weight, 18 parts by weight, 19 parts by weight, 20 parts by weight, 21 parts by weight, 22 parts by weight, 23 parts by weight, 24 parts by weight, or 25 parts by weight, or other specific values within the range; the grape seed extract may be present in an amount of 6 to 15 parts by weight, for example, 6 parts by weight, 6.5 parts by weight, 7 parts by weight, 7.5 parts by weight, 8 parts by weight, 8.5 parts by weight, 9 parts by weight, 9.5 parts by weight, 10 parts by weight, 10.5 parts by weight, 11 parts by weight, 11.5 parts by weight, 12 parts by weight, 12.5 parts by weight, 13 parts by weight, 13.5 parts by weight, 14 parts by weight, 14.5 parts by weight, or 15 parts by weight, or other specific values within the range; and the hydrolyzed fish collagen may be contained in an amount of 2 to 6.5 parts by weight, for example, 2 parts by weight, 2.5 parts by weight, 3 parts by weight, 3.5 parts by weight, 4 parts by weight, 4.5 parts by weight, 5 parts by weight, 5.5 parts by weight, 6 parts by weight, or 6.5 parts by weight, or other specific values within the range. Within the range, the effects of the components can be effectively exerted, and the acne removing and whitening effects are synergistically achieved.
With reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
with reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage comprises the following components:
in order to further improve the synergistic effect of each component, improve the acne removing and whitening effects and simultaneously improve the absorption rate of the effective components, the application further optimizes the dosage of each component. Although there are many active substances with acne removing and whitening functions in the field, random selection or simple mixing of the substances cannot obtain a beverage with acne removing and whitening functions. On one hand, most of the active substances with the acne removing and whitening functions are organic macromolecular substances or plant extracts, and the active substances are easy to interact in the liquid environment of the beverage, so that flocculation and even precipitation are generated, and the stability of the product is influenced; on the other hand, if the active substances are used in improper proportions, the active substances are likely to compete with each other or even antagonize each other after entering the human body, and cannot be well absorbed and utilized by the human body. The inventor finds out through a great deal of practice that after the four active substances of pomegranate fruit powder, saussurea involucrate culture, grape seed extract and hydrolyzed fish collagen are mixed according to the specific weight part ratio, the beverage product can be ensured to have better stability, and the components can fully play a synergistic effect and be fully absorbed by human bodies.
With reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage further comprises:
28-31 parts of vitamin C.
In this application, through adding vitamin C, can improve comprehensively the taste and the efficiency of beverage. The acne-removing and whitening beverage comprises the vitamin C with the content of 28-31 parts by weight, for example, 28 parts by weight, 28.5 parts by weight, 29 parts by weight, 29.5 parts by weight, 30 parts by weight, 30.5 parts by weight or 31 parts by weight, or other specific values in the range.
With reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage further comprises a flavoring agent and a flavoring essence.
Further, in one possible embodiment, the flavoring agent comprises:
200-300 parts by weight of white granulated sugar,
0.5 to 1.0 part by weight of sucralose, and
100-130 parts by weight of anhydrous citric acid.
Further, in a possible embodiment, the amount of the flavoring essence is 15-60 parts by weight.
In the application, in order to further improve the mouthfeel of the beverage, flavoring agents, such as white granulated sugar, sucralose, citric acid, food essence and the like, are further added. Under the action of the auxiliary materials, the beverage can give consideration to the tastes of drinkers in all ages. Wherein the white granulated sugar comprises 200 to 300 parts by weight of the flavoring agent, for example, 200 parts by weight, 210 parts by weight, 220 parts by weight, 230 parts by weight, 240 parts by weight, 250 parts by weight, 260 parts by weight, 270 parts by weight, 280 parts by weight, 290 parts by weight, or 300 parts by weight, or other specific values within the range; the sucralose may be present in an amount of 0.5 to 1.0 part by weight, for example, 0.5, 0.6, 0.7, 0.8, 0.9, or 1.0 part by weight, or other specific values within the range; and the anhydrous citric acid is contained in an amount of 100 to 130 parts by weight, and for example, may be 100 parts by weight, 105 parts by weight, 110 parts by weight, 115 parts by weight, 120 parts by weight, 125 parts by weight, or 130 parts by weight, or other specific values within the range.
With reference to the first aspect, in one possible embodiment, the acne removing and whitening beverage further comprises:
0.02-0.04 parts by weight of naringin, and
0.02-0.04 parts by weight of rhoifolin.
By adding naringin and rhoifolin, the whitening effect of the acne-removing whitening beverage can be further improved. In the present application, the content of naringin in the acne-removing and whitening beverage is 0.02 to 0.04 parts by weight, for example, 0.02 part by weight, 0.025 part by weight, 0.030 part by weight, 0.035 part by weight, or 0.04 part by weight, or other specific values within the range; and the content of the rhoifolin is 0.02 to 0.04 parts by weight, for example, 0.02 parts by weight, 0.025 parts by weight, 0.030 parts by weight, 0.035 parts by weight, or 0.04 parts by weight, or other specific values within the range.
In a possible embodiment in combination with the first aspect, the acne removing and whitening beverage further includes 345 to 590 parts by weight of water, for example, 345 parts by weight, 350 parts by weight, 360 parts by weight, 370 parts by weight, 380 parts by weight, 390 parts by weight, 400 parts by weight, 410 parts by weight, 420 parts by weight, 430 parts by weight, 440 parts by weight, 450 parts by weight, 460 parts by weight, 470 parts by weight, 480 parts by weight, 490 parts by weight, 500 parts by weight, 510 parts by weight, 520 parts by weight, 530 parts by weight, 540 parts by weight, 550 parts by weight, 560 parts by weight, 570 parts by weight, 580 parts by weight, 590 parts by weight, or other specific values within the range. The content of the water is preferably 390 to 410 parts by weight. By adding a specific amount of water, the individual components can be maintained within a specific effective concentration range.
In a second aspect, the application provides a preparation method of the acne removing and whitening beverage, which comprises the following steps:
dissolving the above components in water, mixing, and sterilizing.
In the application, the preparation method is simple and rapid, and the beverage with good acne removing and whitening effects can be provided.
In combination with the second aspect, in one possible embodiment, the preparation method includes:
respectively dispersing pomegranate fruit powder, saussurea involucrate culture, grape seed extract, hydrolyzed fish collagen and white granulated sugar in water, mixing, heating to 80-85 ℃ (for example, 80 ℃, 81 ℃, 82 ℃, 83 ℃, 84 ℃ or 85 ℃, or other specific values in the range) for fully dissolving, then cooling to 30-35 ℃ (for example, 30 ℃, 31 ℃, 32 ℃, 33 ℃, 34 ℃ or 35 ℃, or other specific values in the range), adding other components, heating to 80-85 ℃ (for example, 80 ℃, 81 ℃, 82 ℃, 83 ℃, 84 ℃, or 85 ℃, or other specific values in the range), keeping the temperature for 10-15 min (for example, 10min, 11min, 12min, 13min, 14min or 15min, or other specific values in the range), and sterilizing.
By adopting the above-mentioned operation process, it can be ensured that each substance sufficiently functions and the active ingredient is not destroyed.
In combination with the second aspect, in one possible embodiment, the white granulated sugar is dissolved with hot water at 45 ℃ to 55 ℃. At this temperature, the white granulated sugar can be dissolved more quickly.
In combination with the second aspect, in one possible embodiment, the pomegranate fruit powder, the snow lotus culture, the grape seed extract and the hydrolyzed fish collagen are each dispersed in water and then filtered using an 80-mesh filter. By filtering, unwanted foreign particles can be effectively removed.
With reference to the second aspect, in one possible embodiment, the preparation method further includes: dissolving at least part of the other components except water in water to obtain aqueous solution. The intimate mixing between the components during the preparation of the beverage is facilitated by pre-dissolving at least part of the other components in water to form an aqueous solution. Here, water used to dissolve the respective components is contained in the water contained in the acne removing and whitening beverage, that is, the water contained in the acne removing and whitening beverage is the total water amount.
In a possible embodiment, in combination with the second aspect, the sterilization is heating at 115 ℃ for 30 seconds. Under the above conditions, sterilization can be efficiently performed.
The acne-removing and whitening beverage can effectively remove acne and whiten skin, and is free of side effects, high in absorption efficiency, good in portability and high in market acceptance.
Examples
Sources of materials
Pomegranate fruit powder, purchased from Beijing Condita international trade company;
saussurea involucrate culture, DALIAPIREK biotechnology GmbH;
grape seed extract, available from shanghai cheng-food materials ltd; and
hydrolyzed fish collagen, purchased from taiwan jiele biotechnology limited.
Example 1
The acne-removing and whitening beverage according to the application is prepared by adopting the following preparation method:
respectively dispersing 23.5kg of pomegranate fruit powder, 15kg of saussurea involucrate culture, 14kg of grape seed extract and 6.5kg of hydrolyzed fish collagen in water, and then filtering by adopting an 80-mesh filter; dissolving 250kg of white granulated sugar in hot water of 50 ℃; and 30kg of vitamin C, 115kg of citric acid anhydrous and 0.8kg of sucralose were dissolved in water, respectively. Mixing the pomegranate fruit powder, the saussurea involucrate culture, the grape seed extract and the hydrolyzed fish collagen which are dissolved and filtered with the dissolved white granulated sugar solution, heating to 82 ℃ for full dissolution, then cooling to 32 ℃, adding the dissolved vitamin C, the citric acid and the sucralose, adding 45kg of edible essence and supplementing water (the total water consumption is 500.2kg), heating to 80 ℃, keeping the temperature for 15min, and sterilizing at 115 ℃ for 30 seconds to obtain the acne-removing and whitening drink.
Example 2
The acne-removing and whitening beverage according to the application is prepared by adopting the following preparation method:
respectively dispersing 28kg of pomegranate fruit powder, 14kg of saussurea involucrate culture, 8kg of grape seed extract and 4.5kg of hydrolyzed fish collagen in water, and filtering by adopting an 80-mesh filter; dissolving 250kg of white granulated sugar in hot water at 55 ℃; and 30kg of vitamin C, 115kg of citric acid anhydrous and 0.8kg of sucralose were dissolved in water, respectively. Mixing the pomegranate fruit powder, the saussurea involucrate culture, the grape seed extract and the hydrolyzed fish collagen which are dissolved and filtered with the dissolved white granulated sugar solution, heating to 85 ℃ for full dissolution, then cooling to 30 ℃, adding the dissolved vitamin C, the citric acid and the sucralose, adding 45kg of edible essence and supplementing water (total water consumption is 504.7kg), heating to 82 ℃, keeping the temperature for 13min, and sterilizing at 115 ℃ for 30 seconds to obtain the acne-removing and whitening drink.
Example 3
The acne-removing and whitening beverage according to the application is prepared by adopting the following preparation method:
respectively dispersing 27kg of pomegranate fruit powder, 14kg of saussurea involucrate culture, 11kg of grape seed extract and 6.5kg of hydrolyzed fish collagen in water, and then filtering by adopting an 80-mesh filter; dissolving 250kg of white granulated sugar in hot water at 45 ℃; and 30kg of vitamin C, 115kg of citric acid anhydrous and 0.8kg of sucralose were dissolved in water, respectively. Mixing the pomegranate fruit powder, the saussurea involucrate culture, the grape seed extract and the hydrolyzed fish collagen which are dissolved and filtered with the dissolved white granulated sugar solution, heating to 80 ℃ for full dissolution, then cooling to 33 ℃, adding the dissolved vitamin C, the citric acid and the sucralose, adding 45kg of edible essence and supplementing water (the total water consumption is 500.7kg), heating to 80 ℃, keeping the temperature for 15min, and sterilizing at 115 ℃ for 30 seconds to obtain the acne-removing and whitening drink.
Example 4
The acne-removing and whitening beverage according to the application is prepared by adopting the following preparation method:
respectively dispersing 24.5kg of pomegranate fruit powder, 15kg of saussurea involucrate culture, 15kg of grape seed extract and 5.5kg of hydrolyzed fish collagen in water, and then filtering by adopting an 80-mesh filter; dissolving 250kg of white granulated sugar in hot water of 50 ℃; and 30kg of vitamin C, 115kg of citric acid anhydrous and 0.8kg of sucralose were dissolved in water, respectively. Mixing the pomegranate fruit powder, the saussurea involucrate culture, the grape seed extract and the hydrolyzed fish collagen which are dissolved and filtered with the dissolved white granulated sugar solution, heating to 83 ℃ for full dissolution, then cooling to 35 ℃, adding the dissolved vitamin C, the citric acid and the sucralose, adding 45kg of edible essence and supplementing water (the total water consumption is 500.2kg), heating to 85 ℃, keeping the temperature for 10min, and sterilizing at 115 ℃ for 30 seconds to obtain the acne-removing and whitening drink.
Example 5
The acne removing and whitening beverage was prepared in the same manner as in example 1, except that 0.02kg of naringin and 0.02kg of rhoifolin were dissolved in water to prepare a solution in advance and added to the system together with vitamin C and the like.
Example 6
The acne removing and whitening beverage was prepared in the same manner as in example 1, except that 0.04kg of naringin and 0.04kg of rhoifolin were dissolved in water to prepare a solution in advance and added to the system together with vitamin C, etc.
Examples of the experiments
The beneficial effects of the present application are further illustrated by experiments as follows:
the acne removing and whitening beverages prepared in examples 1 to 6 were subjected to the following evaluation experiments.
Experimental example 1
The removal effect of the acne removing and whitening beverage according to the application on the golden hamster back acne model is researched.
The experimental method comprises the following steps: selecting 54 golden hamster, breeding for 7 days, dividing the golden hamster into 9 groups on average, each group comprises 6 mice, removing hair on sebaceous gland spots on both sides of the back of the golden hamster 24h before molding, and balancing for 1 day after hair removal. Testosterone was applied to bilateral sebaceous gland plaques of 8 groups of golden hamster 1 time per day, the size of sebaceous gland plaques before and after molding was measured with a vernier caliper and the area was calculated (S ═ 3.14 × 1/4 × DL × DT, where DL denotes the maximum longitudinal diameter and DT denotes the maximum transverse diameter), and the remaining group was used as a blank group. After 8 groups of models were completed, 1 group corresponded to the model building group (physiological saline was applied to the model building site, and the normal saline was applied 2 times a day for 8 weeks), 1 group corresponded to the positive group (acne cryptone gel was applied to the model building site, and the gel was applied 2 times a day for 8 weeks), and the remaining 6 groups corresponded to examples 1 to 6 (acne-removing and whitening beverages prepared according to examples 1 to 6 of the present application were respectively taken), and the area size of each group of sebaceous gland plaques before and after the administration was measured by a vernier caliper and the area change was calculated, and the results are shown in table 1 below.
TABLE 1 golden hamster sebaceous gland speckle area/mm before and after experiment2
| Group of | Before application | After application |
| Blank group | 27.19±4.76 | 33.25±3.07 |
| Molding set | 42.78±4.41 | 39.81±4.74 |
| Positive group | 38.05±8.23 | 27.72±2.23 |
| Example 1 | 41.89±2.30 | 24.51±4.83 |
| Example 2 | 42.11±2.89 | 25.89±4.66 |
| Example 3 | 41.22±2.76 | 24.96±4.17 |
| Example 4 | 40.03±2.64 | 26.38±3.70 |
| Example 5 | 43.65±2.37 | 23.54±3.91 |
| Example 6 | 42.18±2.58 | 23.14±3.83 |
As can be seen from table 1, the acne-removing whitening beverages prepared in examples 1 to 6 of the present application have good effect on inhibiting sebaceous gland plaques of animals, and compared with the blank group, the significance P is less than 0.01, even slightly more than that of the positive group (the acne-cryptolone gel is applied at the model building site). In particular, examples 5 and 6, in which naringin and rhoifolin were further added to the beverage, enabled further reduction in the sebaceous gland plaque area of the golden hamster.
Experimental example 2
84 healthy subjects who passed a good non-invasive examination of the skin, had no history of any skin and systemic diseases, had no abnormality in the skin at the test site, and had no allergic phenomenon to the test product were invited as subjects (all women aged 25 to 45 years), and the subjects were divided into 7 groups of 12 persons each. During the test period, 6 groups of subjects were each administered the acne-removing whitening beverages prepared according to examples 1 to 6 of the present application, while the other 1 group received the same sour-sweet ratio and perfume type of commercial placebo beverage (blank group); the experiment was performed using a double-blind, double-simulated, placebo-controlled experiment.
After the testee takes the medicine for 8 weeks, testing the MI value of the skin melanin content, representing the melanin index, wherein the MI value is larger, and the skin melanin content is higher; test skin Brightness L*A value representing skin brightness, the change of which represents the change of skin black-white degree, and the larger the value, the more white the color is; a is*Represents the degree of reddish green, + a*Represents red, -a*Represents green; b*Represents the degree of blue-yellow, + b*Represents yellow, -b*Represents blue; ITA°The value (individual type angle) characterizes the skin brightness, calculated from equation (1), ITA°The larger the value, the brighter the skin, and conversely, the darker the skin.
ITA°＝[Arctan(L*-50/b*)]×180/π (1)
The capacitance of the skin stratum corneum is measured to reflect the moisture content of the human skin stratum corneum, and the larger the measured value is, the higher the moisture content of the skin stratum corneum is represented, and the better the moisturizing effect is.
Statistical tests are carried out by adopting IBM SPSS Statistics 23.0 statistical software, the normality test P is more than 0.05, the data is shown to be obeyed with the normality distribution, the pairing t test is carried out, the non-parametric wilcoxon test is adopted when the data is not obeyed with the normal distribution, and the significance is realized when the P is less than 0.05.
TABLE 2 skin melanin content variation (X + -SD, n ═ 24)
| Group of | Before the experiment | After the test |
| Blank group | 198.37±27.11 | 197.45±28.03 |
| Example 1 | 199.63±30.19 | 187.55±27.73 |
| Example 2 | 199.12±28.76 | 188.22±28.12 |
| Example 3 | 198.65±31.29 | 187.43±27.33 |
| Example 4 | 200.57±27.33 | 188.57±27.56 |
| Example 5 | 198.24±28.88 | 185.64±26.89 |
| Example 6 | 199.33±27.59 | 185.73±27.65 |
As can be seen from table 2, the acne-removing whitening beverages prepared in examples 1 to 6 of the present application have a good effect of inhibiting the melanin content of the skin, and the significance P is less than 0.05 compared with the blank group. In particular, examples 5 and 6, in which naringin and rhoifolin were further added to the beverage, enabled the skin melanin content to be further reduced, demonstrating that a certain whitening effect was exhibited during the test period.
TABLE 3 skin L*Variation (X + -SD, n is 24)
| Group of | Before the experiment | After the test |
| Blank group | 63.62±2.02 | 64.73±2.61 |
| Example 1 | 63.67±2.15 | 66.51±1.36 |
| Example 2 | 63.58±1.98 | 66.42±1.67 |
| Example 3 | 63.22±2.23 | 66.47±1.48 |
| Example 4 | 63.76±2.17 | 66.38±1.84 |
| Example 5 | 63.28±2.06 | 66.88±1.29 |
| Example 6 | 63.50±2.01 | 66.91±1.33 |
As can be seen from table 3, the acne removing and whitening beverages prepared in examples 1 to 6 of the present application have been applied to the skin L*The improvement in value is good, significance P compared to the blank group<0.05. In particular, examples 5 and 6, in which naringin and rhoifolin were further added to the beverage, were able to further enhance the skin L*The values demonstrate that a certain whitening effect is exhibited within the test period.
Table 4 variation of skin ITA ° values (X ± SD, n ═ 24)
| Group of | Before the experiment | After the test |
| Blank group | 43.87±6.45 | 44.19±6.34 |
| Example 1 | 43.85±6.55 | 46.73±6.35 |
| Example 2 | 43.88±6.26 | 46.52±6.40 |
| Example 3 | 43.75±6.31 | 46.67±6.27 |
| Example 4 | 43.91±6.47 | 46.62±6.48 |
| Example 5 | 43.82±6.35 | 46.98±6.31 |
| Example 6 | 43.84±6.40 | 46.95±6.30 |
As can be seen from table 4, the acne-removing whitening beverages prepared in examples 1 to 6 of the present application have a good effect of improving the skin ITA ° value, and the significance P is less than 0.05 compared with the blank group. Particularly, examples 5 and 6, in which naringin and rhoifolin were further added to the beverage, were able to further enhance the skin ITA ° value, demonstrating that a certain whitening effect was exhibited within the test period.
The study of the results proves that the beverage provided by the application can effectively reduce the content of melanin and has certain whitening effect.
Experimental example 3
The stability of the acne-removing and whitening beverages prepared in examples 1 to 6 is observed by standing at room temperature for 180 days, the color is not greatly changed by visual observation, a small amount of precipitate can be seen at the bottom, and the beverage is detected to be a complex product of a small amount of pomegranate fruit powder extract, but the activity of the functional components of the beverage is not influenced.
A small amount of beverage samples are taken to be detected in a 722 spectrophotometer (room temperature, wavelength 550mm), the light transmittance of the product before storage is 87.3-85.8, and the light transmittance of the product after storage for 180 days is 84.8-83.1 without obvious reduction.
The light transmittance of the beverage provided by each example is not reduced by more than 5% before and after storage, which shows that the beverage provided by the invention has good stability.
The above-described embodiments of the present application are only examples of the present application and should not be construed as limiting the present application, and those skilled in the art can make modifications without inventive contribution as required after reading the present specification, however, any modifications, equivalents, improvements, etc. within the spirit and principle of the present application should be included in the scope of the present application.
Claims (10)
1. The acne-removing and whitening beverage is characterized by comprising the following components:
2. the acne-removing whitening beverage according to claim 1, which is characterized by comprising the following components:
3. the acne-removing whitening beverage according to claim 1, which is characterized by comprising the following components:
4. the acne-removing whitening beverage according to claim 1, which is characterized by comprising the following components:
5. the acne-removing whitening beverage according to claim 1, which is characterized by comprising the following components:
6. the acne removing and whitening beverage according to any one of claims 1 to 5, further comprising:
28-31 parts of vitamin C.
7. The acne removing and whitening beverage according to any one of claims 1 to 5, further comprising a flavoring agent and a flavoring essence,
further, the flavoring agent comprises:
200-300 parts by weight of white granulated sugar,
0.5 to 1.0 part by weight of sucralose, and
100 to 130 parts by weight of anhydrous citric acid,
furthermore, the amount of the edible essence is 15-60 parts by weight,
further, the acne removing and whitening beverage also comprises 345-590 parts by weight of water, preferably 390-410 parts by weight of water.
8. The acne removing and whitening beverage according to any one of claims 1 to 5, further comprising:
0.02-0.04 parts by weight of naringin, and
0.02-0.04 parts by weight of rhoifolin.
9. The preparation method of the acne-removing and whitening beverage according to any one of claims 1 to 8, which is characterized by comprising the following steps:
dissolving the above components in water, mixing, and sterilizing.
10. The method of manufacturing according to claim 9, comprising:
respectively dispersing pomegranate fruit powder, saussurea involucrate culture, grape seed extract, hydrolyzed fish collagen and white granulated sugar in water, mixing, heating to 80-85 deg.C for fully dissolving, cooling to 30-35 deg.C, adding other components, heating to 80-85 deg.C, keeping the temperature for 10-15 min, sterilizing,
preferably, the white granulated sugar is dissolved by hot water with the temperature of 45-55 ℃,
preferably, pomegranate fruit powder, saussurea involucrate culture, grape pip extract and hydrolyzed fish collagen are respectively dispersed in water and then filtered by a 80-mesh filter,
preferably, the preparation method further comprises: dissolving at least part of the other components except water in water to obtain aqueous solution,
preferably, the sterilization is heating at 115 ℃ for 30 seconds.
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Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4297348A (en) * | 1980-04-11 | 1981-10-27 | Rush-Hampton Industries, Inc. | Composition and method for the treatment of acne |
| CN103549601A (en) * | 2013-11-18 | 2014-02-05 | 北京姿美堂生物技术有限公司 | Women care and nourishing beverage |
| CN104306423A (en) * | 2014-10-30 | 2015-01-28 | 大连普瑞康生物技术有限公司 | Application of saussurea involucrate culture in preparing product capable of suppressing skin pigmentation |
| CN106349308A (en) * | 2016-08-02 | 2017-01-25 | 重庆工商大学 | Method for extracting apigenin-7-O-neohesperidoside from paeonia suffruticosa andrews and application of apigenin-7-O-neohesperidoside |
| CN106360740A (en) * | 2016-08-31 | 2017-02-01 | 安徽旺润生物科技有限公司 | Feature beautifying and skin nourishing nutrient composition |
| CN106632546A (en) * | 2016-11-16 | 2017-05-10 | 广东石油化工学院 | Method for preparing two chemical reference substances of Rhoifolin and naringin simultaneously |
| CN106819741A (en) * | 2017-01-20 | 2017-06-13 | 世茂（苏州）生物科技有限公司 | Compound fruit-flavored beverage of a kind of Isin glue collagen and preparation method thereof |
| CN108785174A (en) * | 2018-07-27 | 2018-11-13 | 大埔县通美实业有限公司 | A kind of plain face frost and preparation method thereof rich in grapefruit abstract |
| CN111493243A (en) * | 2020-05-27 | 2020-08-07 | 郇玉芝 | Beverage for assisting whitening, brightening skin color, resisting saccharification and supplementing collagen and preparation method thereof |
| CN111939099A (en) * | 2020-09-04 | 2020-11-17 | 陈广文 | Acne-removing moisturizing mask and preparation method thereof |
| CN111955718A (en) * | 2019-10-29 | 2020-11-20 | 北京东方红航天生物技术股份有限公司 | Snow lotus red wine powder and preparation method and application thereof |
| CN113133512A (en) * | 2021-03-15 | 2021-07-20 | 梅州市卫士生物科技有限公司 | A beverage containing naringin and its preparation method |
| CN113749260A (en) * | 2020-06-03 | 2021-12-07 | 石家庄以岭药业股份有限公司 | Collagen peptide composition and preparation method thereof |
-
2021
- 2021-12-30 CN CN202111657115.4A patent/CN114287547A/en active Pending
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4297348A (en) * | 1980-04-11 | 1981-10-27 | Rush-Hampton Industries, Inc. | Composition and method for the treatment of acne |
| CN103549601A (en) * | 2013-11-18 | 2014-02-05 | 北京姿美堂生物技术有限公司 | Women care and nourishing beverage |
| CN104306423A (en) * | 2014-10-30 | 2015-01-28 | 大连普瑞康生物技术有限公司 | Application of saussurea involucrate culture in preparing product capable of suppressing skin pigmentation |
| CN106349308A (en) * | 2016-08-02 | 2017-01-25 | 重庆工商大学 | Method for extracting apigenin-7-O-neohesperidoside from paeonia suffruticosa andrews and application of apigenin-7-O-neohesperidoside |
| CN106360740A (en) * | 2016-08-31 | 2017-02-01 | 安徽旺润生物科技有限公司 | Feature beautifying and skin nourishing nutrient composition |
| CN106632546A (en) * | 2016-11-16 | 2017-05-10 | 广东石油化工学院 | Method for preparing two chemical reference substances of Rhoifolin and naringin simultaneously |
| CN106819741A (en) * | 2017-01-20 | 2017-06-13 | 世茂（苏州）生物科技有限公司 | Compound fruit-flavored beverage of a kind of Isin glue collagen and preparation method thereof |
| CN108785174A (en) * | 2018-07-27 | 2018-11-13 | 大埔县通美实业有限公司 | A kind of plain face frost and preparation method thereof rich in grapefruit abstract |
| CN111955718A (en) * | 2019-10-29 | 2020-11-20 | 北京东方红航天生物技术股份有限公司 | Snow lotus red wine powder and preparation method and application thereof |
| CN111493243A (en) * | 2020-05-27 | 2020-08-07 | 郇玉芝 | Beverage for assisting whitening, brightening skin color, resisting saccharification and supplementing collagen and preparation method thereof |
| CN113749260A (en) * | 2020-06-03 | 2021-12-07 | 石家庄以岭药业股份有限公司 | Collagen peptide composition and preparation method thereof |
| CN111939099A (en) * | 2020-09-04 | 2020-11-17 | 陈广文 | Acne-removing moisturizing mask and preparation method thereof |
| CN113133512A (en) * | 2021-03-15 | 2021-07-20 | 梅州市卫士生物科技有限公司 | A beverage containing naringin and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 高书亮;卢元元;安利娟;舒积成;刘建群;张锐;任晓静;: "野漆树苷对雷公藤甲素诱导肝损伤的保护作用", 中药药理与临床, vol. 28, no. 06, pages 18 - 20 * |
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