CN114286670B - 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物 - Google Patents

含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物 Download PDF

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Publication number
CN114286670B
CN114286670B CN202080059970.2A CN202080059970A CN114286670B CN 114286670 B CN114286670 B CN 114286670B CN 202080059970 A CN202080059970 A CN 202080059970A CN 114286670 B CN114286670 B CN 114286670B
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eye
drops
ophthalmic composition
aqueous ophthalmic
sodium
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CN114286670A (zh
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森岛健司
浅田博之
桃川雄介
神村明日香
远藤健一
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Santen Pharmaceutical Co Ltd
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Santen Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN202080059970.2A 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物 Active CN114286670B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311818685.6A CN117771172A (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物

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JP2019154525 2019-08-27
JP2019-154525 2019-08-27
PCT/JP2020/031917 WO2021039748A1 (ja) 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

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CN202311818685.6A Division CN117771172A (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物

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CN114286670A CN114286670A (zh) 2022-04-05
CN114286670B true CN114286670B (zh) 2024-01-16

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CN202080059970.2A Active CN114286670B (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物
CN202311818685.6A Pending CN117771172A (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物

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Country Status (7)

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JP (3) JP6966667B2 (enExample)
KR (2) KR102656181B1 (enExample)
CN (2) CN114286670B (enExample)
MY (1) MY209059A (enExample)
PH (1) PH12022550474A1 (enExample)
TW (1) TWI848171B (enExample)
WO (1) WO2021039748A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202007977RA (en) * 2018-02-28 2020-09-29 Santen Pharmaceutical Co Ltd Ophthalmic composition comprising diquafosol and cationic polymer
JP6966667B2 (ja) * 2019-08-27 2021-11-17 参天製薬株式会社 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
JP7175431B1 (ja) 2021-03-30 2022-11-18 千寿製薬株式会社 ヘテロシクリデンアセトアミド誘導体含有懸濁液
CN114646705A (zh) * 2022-03-22 2022-06-21 武汉绿合医药科技有限公司 一种地夸磷索钠滴眼液有关物质含量检测方法
JP2024043685A (ja) * 2022-09-20 2024-04-02 参天製薬株式会社 ジクアホソルまたはその塩を含有する眼科用組成物のｐＨの低下を抑制する方法
JP7245383B1 (ja) 2022-09-20 2023-03-23 参天製薬株式会社 ジクアホソルまたはその塩を含有する眼科用組成物のｐＨの低下を抑制する方法
KR20250160050A (ko) 2024-05-03 2025-11-11 삼천당제약주식회사 물리화학적 특성이 개선된 안구건조증 예방 또는 치료용 약학 조성물
CN119970633A (zh) * 2025-03-26 2025-05-13 苏州乐珠制药有限公司 一种地夸磷索钠滴眼液及其制备方法

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CN111757742A (zh) * 2018-02-28 2020-10-09 参天制药株式会社 含有地夸磷索及阳离子性聚合物的眼科用组合物

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US5591426A (en) * 1993-07-02 1997-01-07 Bausch & Lomb Incorporated Ophthalmic solution for artificial tears
US6274626B1 (en) * 1998-12-22 2001-08-14 Bausch & Lomb Incorporated Pheniramine-containing compositions and method for treating allergic responses
CN1413114A (zh) * 1999-12-27 2003-04-23 参天制药株式会社 用于稳定泪液层的体系
CN103096929A (zh) * 2010-09-10 2013-05-08 参天制药株式会社 以组合p2y2受体激动剂和透明质酸或其盐为特征的干眼症治疗剂、干眼症的治疗方法、及干眼症治疗剂的应用
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WO2016195072A1 (ja) * 2015-06-05 2016-12-08 参天製薬株式会社 ソフトコンタクトレンズが装用されたドライアイ患者の眼に点眼されるように用いられることを特徴とするドライアイ治療剤
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Publication number Publication date
WO2021039748A1 (ja) 2021-03-04
KR20220052971A (ko) 2022-04-28
MY209059A (en) 2025-06-18
JP2025031918A (ja) 2025-03-07
JPWO2021039748A1 (ja) 2021-09-30
JP2022003099A (ja) 2022-01-11
CN117771172A (zh) 2024-03-29
KR102656181B1 (ko) 2024-04-08
PH12022550474A1 (en) 2023-03-06
TWI848171B (zh) 2024-07-11
JP7902251B2 (ja) 2026-08-07
JP6966667B2 (ja) 2021-11-17
TW202122094A (zh) 2021-06-16
CN114286670A (zh) 2022-04-05
JP7614069B2 (ja) 2025-01-15
KR20240049646A (ko) 2024-04-16

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