JP6966667B2 - ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 - Google Patents

ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 Download PDF

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Publication number
JP6966667B2
JP6966667B2 JP2021521065A JP2021521065A JP6966667B2 JP 6966667 B2 JP6966667 B2 JP 6966667B2 JP 2021521065 A JP2021521065 A JP 2021521065A JP 2021521065 A JP2021521065 A JP 2021521065A JP 6966667 B2 JP6966667 B2 JP 6966667B2
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aqueous ophthalmic
ophthalmic composition
diquafosol
polyvinylpyrrolidone
eye
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Japanese (ja)
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JPWO2021039748A1 (ja
Inventor
健司 森島
博之 浅田
雄介 桃川
明日香 神村
健一 遠藤
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Santen Pharmaceutical Co Ltd
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Santen Pharmaceutical Co Ltd
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Priority to JP2024228577A priority patent/JP2025031918A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2021521065A 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 Active JP6966667B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021171358A JP7614069B2 (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
JP2024228577A JP2025031918A (ja) 2019-08-27 2024-12-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019154525 2019-08-27
JP2019154525 2019-08-27
PCT/JP2020/031917 WO2021039748A1 (ja) 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

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JP2021171358A Division JP7614069B2 (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

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JPWO2021039748A1 JPWO2021039748A1 (ja) 2021-09-30
JP6966667B2 true JP6966667B2 (ja) 2021-11-17

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Family Applications (3)

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JP2021521065A Active JP6966667B2 (ja) 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
JP2021171358A Active JP7614069B2 (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
JP2024228577A Pending JP2025031918A (ja) 2019-08-27 2024-12-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

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JP2021171358A Active JP7614069B2 (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
JP2024228577A Pending JP2025031918A (ja) 2019-08-27 2024-12-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

Country Status (7)

Country Link
JP (3) JP6966667B2 (enExample)
KR (2) KR20240049646A (enExample)
CN (2) CN117771172A (enExample)
MY (1) MY209059A (enExample)
PH (1) PH12022550474A1 (enExample)
TW (1) TWI848171B (enExample)
WO (1) WO2021039748A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI833406B (zh) * 2018-02-28 2024-02-21 日商參天製藥股份有限公司 含有迪夸弗索（Ｄｉｑｕａｆｏｓｏｌ）及陽離子性聚合物之眼科用組合物
JP7175431B1 (ja) * 2021-03-30 2022-11-18 千寿製薬株式会社 ヘテロシクリデンアセトアミド誘導体含有懸濁液
CN114646705A (zh) * 2022-03-22 2022-06-21 武汉绿合医药科技有限公司 一种地夸磷索钠滴眼液有关物质含量检测方法
JP7245383B1 (ja) 2022-09-20 2023-03-23 参天製薬株式会社 ジクアホソルまたはその塩を含有する眼科用組成物のｐＨの低下を抑制する方法
KR20250160050A (ko) 2024-05-03 2025-11-11 삼천당제약주식회사 물리화학적 특성이 개선된 안구건조증 예방 또는 치료용 약학 조성물
CN119970633A (zh) * 2025-03-26 2025-05-13 苏州乐珠制药有限公司 一种地夸磷索钠滴眼液及其制备方法

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JPH0365270A (ja) 1989-07-31 1991-03-20 Kanzaki Paper Mfg Co Ltd 塗布シートの製造方法
JPH0365270U (enExample) 1989-10-31 1991-06-25
US5358706A (en) * 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
CA2125060C (en) * 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
US5900407A (en) * 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
KR100549904B1 (ko) * 1996-03-27 2006-05-16 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 우리딘트리포스페이트및관련화합물을함유하는섬모운동장해치료용약학조성물
US6274626B1 (en) * 1998-12-22 2001-08-14 Bausch & Lomb Incorporated Pheniramine-containing compositions and method for treating allergic responses
KR20020069224A (ko) * 1999-12-27 2002-08-29 산텐 세이야꾸 가부시키가이샤 누액층의 안정화 시스템
AU6064301A (en) * 2000-05-30 2001-12-11 Santen Pharmaceutical Co Ltd Ectocornea extension promoters
KR101389300B1 (ko) * 2005-02-14 2014-04-25 존슨 앤드 존슨 비젼 케어, 인코포레이티드 안과용 렌즈의 제조방법, 안과용 장치 및 콘택트 렌즈
CN103096929A (zh) * 2010-09-10 2013-05-08 参天制药株式会社 以组合p2y2受体激动剂和透明质酸或其盐为特征的干眼症治疗剂、干眼症的治疗方法、及干眼症治疗剂的应用
JP2012149057A (ja) * 2010-12-28 2012-08-09 Santen Pharmaceut Co Ltd ジクアホソル含有点眼液およびその製造方法、不溶性析出物発生の抑制方法
KR20120077080A (ko) 2010-12-30 2012-07-10 동우 화인켐 주식회사 광학필름 및 이를 이용한 백라이트 유닛
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JP6267003B2 (ja) 2014-02-27 2018-01-24 参天製薬株式会社 ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤
ES2747808T3 (es) * 2014-05-07 2020-03-11 Croma Pharma Ges M B H Solución oftálmica acuosa y método para tratar el síndrome del ojo seco
SG11201705138QA (en) * 2014-12-25 2017-07-28 Santen Pharmaceutical Co Ltd Aqueous ophthalmic solution
CN107635565A (zh) * 2015-06-05 2018-01-26 参天制药株式会社 以向佩戴有软性隐形眼镜的干眼症患者的眼中滴入的方式使用为特征的干眼症治疗剂
TWI833406B (zh) * 2018-02-28 2024-02-21 日商參天製藥股份有限公司 含有迪夸弗索（Ｄｉｑｕａｆｏｓｏｌ）及陽離子性聚合物之眼科用組合物

Also Published As

Publication number Publication date
KR20220052971A (ko) 2022-04-28
TWI848171B (zh) 2024-07-11
CN114286670B (zh) 2024-01-16
MY209059A (en) 2025-06-18
WO2021039748A1 (ja) 2021-03-04
KR102656181B1 (ko) 2024-04-08
JPWO2021039748A1 (ja) 2021-09-30
CN114286670A (zh) 2022-04-05
JP2022003099A (ja) 2022-01-11
CN117771172A (zh) 2024-03-29
TW202122094A (zh) 2021-06-16
JP2025031918A (ja) 2025-03-07
JP7614069B2 (ja) 2025-01-15
KR20240049646A (ko) 2024-04-16
PH12022550474A1 (en) 2023-03-06

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