CN114177267A - A plaster for treating scald and bedsore, and its preparation method - Google Patents
A plaster for treating scald and bedsore, and its preparation method Download PDFInfo
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- CN114177267A CN114177267A CN202210054580.7A CN202210054580A CN114177267A CN 114177267 A CN114177267 A CN 114177267A CN 202210054580 A CN202210054580 A CN 202210054580A CN 114177267 A CN114177267 A CN 114177267A
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- scalds
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- 206010053615 Thermal burn Diseases 0.000 title claims abstract description 49
- 208000004210 Pressure Ulcer Diseases 0.000 title claims abstract description 46
- 239000011505 plaster Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 17
- 241001071917 Lithospermum Species 0.000 claims abstract description 17
- 235000013871 bee wax Nutrition 0.000 claims abstract description 17
- 239000012166 beeswax Substances 0.000 claims abstract description 17
- 239000008159 sesame oil Substances 0.000 claims abstract description 17
- 235000011803 sesame oil Nutrition 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 241000213006 Angelica dahurica Species 0.000 claims abstract description 12
- 239000000203 mixture Substances 0.000 claims description 26
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 14
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 14
- 244000144730 Amygdalus persica Species 0.000 claims description 14
- 244000020518 Carthamus tinctorius Species 0.000 claims description 14
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 14
- 235000006040 Prunus persica var persica Nutrition 0.000 claims description 14
- 229940116229 borneol Drugs 0.000 claims description 14
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 14
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 14
- 239000008367 deionised water Substances 0.000 claims description 10
- 229910021641 deionized water Inorganic materials 0.000 claims description 10
- 238000010298 pulverizing process Methods 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000003809 water extraction Methods 0.000 claims description 10
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 9
- 241000219061 Rheum Species 0.000 claims description 9
- 235000009411 Rheum rhabarbarum Nutrition 0.000 claims description 9
- 244000170916 Paeonia officinalis Species 0.000 claims description 7
- 241000972672 Phellodendron Species 0.000 claims description 6
- 240000004980 Rheum officinale Species 0.000 claims description 5
- 235000008081 Rheum officinale Nutrition 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000000034 method Methods 0.000 claims 3
- 244000301850 Cupressus sempervirens Species 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 6
- 208000027418 Wounds and injury Diseases 0.000 abstract description 5
- 206010052428 Wound Diseases 0.000 abstract description 4
- 206010020718 hyperplasia Diseases 0.000 abstract description 4
- 206010061218 Inflammation Diseases 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 3
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 3
- 241000218691 Cupressaceae Species 0.000 description 6
- 241001106477 Paeoniaceae Species 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
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- A61K36/232—Angelica
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Abstract
The invention discloses a plaster for treating scalds and bedsores and a preparation method thereof, and relates to the technical field of scald plasters, wherein the plaster for treating the scalds and the bedsores comprises the following raw material components in parts by weight: 15-40 parts of angelica dahurica, 20-50 parts of lithospermum, 20-50 parts of honeysuckle stem, 30-60 parts of beeswax, 1200 parts of sesame oil 800-. The plaster for treating scalds and bedsores provided by the invention adopts natural traditional Chinese medicines as raw materials, has an obvious effect of treating the scalds and bedsores, can quickly diminish inflammation and relieve pain, heal wounds, and has no hyperplasia and no side effect after treatment.
Description
Technical Field
The invention relates to the technical field of scald plasters, in particular to a plaster for treating scalds and bedsores and a preparation method thereof.
Background
Scald is an injury caused by high temperature liquid, high temperature solid or high temperature steam, and belongs to common diseases. The main manifestations are redness, swelling, blisters, and pain. If the treatment is not timely, scar hyperplasia and infection are easily caused, and the serious patient can cause shock.
Bedsores, which are lesions, ulcers and even necrosis due to the lack of nutrition of the skin and subcutaneous tissues resulting from prolonged pressure on the skin of a body part which affects blood circulation.
At present, the ointment for treating scald on the market can not quickly heal the wound, has side effects, is easy to proliferate after treatment, and also has no effect of treating bedsore.
Disclosure of Invention
The plaster for treating scalds and bedsores provided by the invention adopts natural traditional Chinese medicines as raw materials, has an obvious effect of treating the scalds and bedsores, can quickly diminish inflammation and relieve pain, heal wounds, and has no hyperplasia and no side effect after treatment.
The plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 15-40 parts of angelica dahurica, 20-50 parts of lithospermum, 20-50 parts of honeysuckle stem, 30-60 parts of beeswax, 1200 parts of sesame oil 800-.
Preferably, the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 27.5 parts of angelica dahurica, 35 parts of lithospermum, 35 parts of honeysuckle stem, 45 parts of beeswax, 1000 parts of sesame oil, 15 parts of borneol, 20 parts of rhubarb, 20 parts of radix curcumae, 17.5 parts of phellodendron, 15 parts of red peony root, 7.5 parts of safflower and 20 parts of peach kernel.
Preferably, the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 15 parts of angelica dahurica, 20 parts of lithospermum, 20 parts of honeysuckle stem, 30 parts of beeswax, 800 parts of sesame oil, 10 parts of borneol, 10 parts of rhubarb, 10 parts of radix curcumae, 10 parts of golden cypress, 10 parts of red paeony root, 5 parts of safflower and 10 parts of peach kernel.
Preferably, the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 40 parts of angelica dahurica, 50 parts of lithospermum, 50 parts of honeysuckle stem, 60 parts of beeswax, 1200 parts of sesame oil, 20 parts of borneol, 30 parts of rhubarb, 30 parts of radix curcumae, 25 parts of phellodendron, 20 parts of red peony root, 10 parts of safflower and 30 parts of peach kernel.
The invention also aims to protect the preparation method of the plaster for treating scalds and bedsores, which comprises the following steps:
s1, cleaning, drying and crushing radix angelicae, lithospermum, honeysuckle stem, rheum officinale, radix curcumae, golden cypress, radix paeoniae rubra, safflower and peach kernel to obtain a mixture A, adding deionized water into the mixture A for water extraction, and concentrating to obtain an extracting solution;
s2, crushing borneol, adding beeswax and sesame oil, and uniformly stirring to obtain a mixture B;
and S3, adding the extracting solution into the mixture B, and uniformly stirring to prepare the plaster for treating scalds and bedsores.
Preferably, in step S1, the pulverization is 80-100 mesh.
Preferably, in step S1, the weight part ratio of the mixture a to the deionized water is 1: 4-6; the water extraction is carried out at 110-120 ℃ for 3 times, and each time lasts for 3-5 hours.
Preferably, in step S1, the concentration is performed to a density of 1.2g/cm3。
Preferably, in step S2, the pulverization is 80-100 mesh.
The invention has the beneficial effects that:
(1) the plaster for treating scalds and bedsores provided by the invention adopts natural traditional Chinese medicines as raw materials, has an obvious effect of treating the scalds and bedsores, can quickly diminish inflammation and relieve pain, heal wounds, and has no hyperplasia and no side effect after treatment.
(2) The preparation method of the plaster for treating scalds and bedsores, provided by the invention, is simple to operate, stable in technology, easy to obtain raw materials, excellent in effect of the prepared product and high in commercial value.
Detailed Description
Hereinafter, embodiments of the present invention will be described in detail. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
It is to be noted that, unless otherwise specified, technical or scientific terms used herein shall have the ordinary meaning as understood by those skilled in the art to which the invention pertains.
Example 1
The embodiment provides a plaster for treating scalds and bedsores, which comprises the following raw material components in parts by weight: 27.5 parts of angelica dahurica, 35 parts of lithospermum, 35 parts of honeysuckle stem, 45 parts of beeswax, 1000 parts of sesame oil, 15 parts of borneol, 20 parts of rhubarb, 20 parts of radix curcumae, 17.5 parts of phellodendron, 15 parts of red peony root, 7.5 parts of safflower and 20 parts of peach kernel.
The preparation method of the plaster for treating scalds and bedsores comprises the following steps:
s1, cleaning, drying and crushing radix angelicae, lithospermum, honeysuckle stem, rheum officinale, radix curcumae, golden cypress, radix paeoniae rubra, safflower and peach kernel to obtain a mixture A, adding deionized water into the mixture A for water extraction, and concentrating to obtain an extracting solution;
s2, crushing borneol, adding beeswax and sesame oil, and uniformly stirring to obtain a mixture B;
and S3, adding the extracting solution into the mixture B, and uniformly stirring to prepare the plaster for treating scalds and bedsores.
In step S1, the pulverization is performed to 100 mesh.
In step S1, the weight portion ratio of the mixture a to the deionized water is 1: 5; the water extraction is carried out at 120 ℃ for 3 times, and each time lasts for 4 hours.
In step S1, the concentration is carried out until the density is 1.2g/cm3。
In step S2, the pulverization is performed to 100 mesh.
Example 2
The embodiment provides a plaster for treating scalds and bedsores, which comprises the following raw material components in parts by weight: 15 parts of angelica dahurica, 20 parts of lithospermum, 20 parts of honeysuckle stem, 30 parts of beeswax, 800 parts of sesame oil, 10 parts of borneol, 10 parts of rhubarb, 10 parts of radix curcumae, 10 parts of golden cypress, 10 parts of red paeony root, 5 parts of safflower and 10 parts of peach kernel.
The preparation method of the plaster for treating scalds and bedsores comprises the following steps:
s1, cleaning, drying and crushing radix angelicae, lithospermum, honeysuckle stem, rheum officinale, radix curcumae, golden cypress, radix paeoniae rubra, safflower and peach kernel to obtain a mixture A, adding deionized water into the mixture A for water extraction, and concentrating to obtain an extracting solution;
s2, crushing borneol, adding beeswax and sesame oil, and uniformly stirring to obtain a mixture B;
and S3, adding the extracting solution into the mixture B, and uniformly stirring to prepare the plaster for treating scalds and bedsores.
In step S1, the pulverization is performed to 100 mesh.
In step S1, the weight portion ratio of the mixture a to the deionized water is 1: 5; the water extraction is carried out at 120 ℃ for 3 times, and each time lasts for 4 hours.
In step S1, the concentration is carried out until the density is 1.2g/cm3。
In step S2, the pulverization is performed to 100 mesh.
Example 3
The embodiment provides a plaster for treating scalds and bedsores, which comprises the following raw material components in parts by weight: 40 parts of angelica dahurica, 50 parts of lithospermum, 50 parts of honeysuckle stem, 60 parts of beeswax, 1200 parts of sesame oil, 20 parts of borneol, 30 parts of rhubarb, 30 parts of radix curcumae, 25 parts of phellodendron, 20 parts of red peony root, 10 parts of safflower and 30 parts of peach kernel.
The preparation method of the plaster for treating scalds and bedsores comprises the following steps:
s1, cleaning, drying and crushing radix angelicae, lithospermum, honeysuckle stem, rheum officinale, radix curcumae, golden cypress, radix paeoniae rubra, safflower and peach kernel to obtain a mixture A, adding deionized water into the mixture A for water extraction, and concentrating to obtain an extracting solution;
s2, crushing borneol, adding beeswax and sesame oil, and uniformly stirring to obtain a mixture B;
and S3, adding the extracting solution into the mixture B, and uniformly stirring to prepare the plaster for treating scalds and bedsores.
In step S1, the pulverization is performed to 100 mesh.
In step S1, the weight portion ratio of the mixture a to the deionized water is 1: 5; the water extraction is carried out at 120 ℃ for 3 times, and each time lasts for 4 hours.
In step S1, the concentration is concentratedTo a density of 1.2g/cm3。
In step S2, the pulverization is performed to 100 mesh.
Test examples
Test of the therapeutic effects of the plasters prepared in examples 1 to 3 for the treatment of scalds and bedsores
The test method comprises the following steps: 300 patients with local scald were randomly selected and randomly divided into 3 groups, and the plasters for treating scald and bedsore prepared in examples 1-3 of the present invention were used respectively,
the ointment is applied to the affected part three times a day, and is continuously applied for 7 days, and the results are shown in Table 1.
TABLE 1
| Example 1 | Example 2 | Example 3 | |
| Cure/human | 95 | 94 | 94 |
| Effective/human | 5 | 6 | 6 |
| Invalid/human | 0 | 0 | 0 |
As can be seen from table 1, the plasters prepared in examples 1 to 3 of the present invention for treating scalds and bedsores have a cure rate of 94% or more, and a total effective rate of 100%.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention, and they should be construed as being included in the following claims and description.
Claims (9)
1. A plaster for treating scalds and bedsores is characterized in that: the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 15-40 parts of angelica dahurica, 20-50 parts of lithospermum, 20-50 parts of honeysuckle stem, 30-60 parts of beeswax, 1200 parts of sesame oil 800-.
2. A plaster for the treatment of scalds and bedsores according to claim 1, characterized in that: the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 27.5 parts of angelica dahurica, 35 parts of lithospermum, 35 parts of honeysuckle stem, 45 parts of beeswax, 1000 parts of sesame oil, 15 parts of borneol, 20 parts of rhubarb, 20 parts of radix curcumae, 17.5 parts of phellodendron, 15 parts of red peony root, 7.5 parts of safflower and 20 parts of peach kernel.
3. A plaster for the treatment of scalds and bedsores according to claim 1, characterized in that: the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 15 parts of angelica dahurica, 20 parts of lithospermum, 20 parts of honeysuckle stem, 30 parts of beeswax, 800 parts of sesame oil, 10 parts of borneol, 10 parts of rhubarb, 10 parts of radix curcumae, 10 parts of golden cypress, 10 parts of red paeony root, 5 parts of safflower and 10 parts of peach kernel.
4. A plaster for the treatment of scalds and bedsores according to claim 1, characterized in that: the plaster for treating scalds and bedsores comprises the following raw material components in parts by weight: 40 parts of angelica dahurica, 50 parts of lithospermum, 50 parts of honeysuckle stem, 60 parts of beeswax, 1200 parts of sesame oil, 20 parts of borneol, 30 parts of rhubarb, 30 parts of radix curcumae, 25 parts of phellodendron, 20 parts of red peony root, 10 parts of safflower and 30 parts of peach kernel.
5. The process for preparing a plaster for treating scalds and bedsores as claimed in any of claims 1-4, wherein: the preparation method comprises the following steps:
s1, cleaning, drying and crushing radix angelicae, lithospermum, honeysuckle stem, rheum officinale, radix curcumae, golden cypress, radix paeoniae rubra, safflower and peach kernel to obtain a mixture A, adding deionized water into the mixture A for water extraction, and concentrating to obtain an extracting solution;
s2, crushing borneol, adding beeswax and sesame oil, and uniformly stirring to obtain a mixture B;
and S3, adding the extracting solution into the mixture B, and uniformly stirring to prepare the plaster for treating scalds and bedsores.
6. The method for preparing a plaster for treating scalds and bedsores according to claim 5, wherein: in step S1, the pulverization is carried out to 80-100 meshes.
7. The method for preparing a plaster for treating scalds and bedsores according to claim 5, wherein: in step S1, the weight portion ratio of the mixture a to the deionized water is 1: 4-6; the water extraction is carried out at 110-120 ℃ for 3 times, and each time lasts for 3-5 hours.
8. The composition of claim 5 for treatingThe preparation method of the plaster for treating scalds and bedsores is characterized by comprising the following steps: in step S1, the concentration is carried out until the density is 1.2g/cm3。
9. The method for preparing a plaster for treating scalds and bedsores according to claim 5, wherein: in step S2, the pulverization is carried out to 80-100 meshes.
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| CN202210054580.7A CN114177267A (en) | 2022-01-18 | 2022-01-18 | A plaster for treating scald and bedsore, and its preparation method |
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| CN102429976A (en) * | 2011-12-07 | 2012-05-02 | 尚如湖铁医院 | Traditional Chinese medicinal ointment preparation for treating burns and scalds and preparation method thereof |
| CN107625830A (en) * | 2017-09-06 | 2018-01-26 | 李春梅 | Hide MEBO of more removing necrosis and promoting granulation |
| CN107854551A (en) * | 2017-10-31 | 2018-03-30 | 安徽老同桌生物科技有限公司 | A kind of burn pain-relieving paste formulation |
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- 2022-01-18 CN CN202210054580.7A patent/CN114177267A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429976A (en) * | 2011-12-07 | 2012-05-02 | 尚如湖铁医院 | Traditional Chinese medicinal ointment preparation for treating burns and scalds and preparation method thereof |
| CN107625830A (en) * | 2017-09-06 | 2018-01-26 | 李春梅 | Hide MEBO of more removing necrosis and promoting granulation |
| CN107854551A (en) * | 2017-10-31 | 2018-03-30 | 安徽老同桌生物科技有限公司 | A kind of burn pain-relieving paste formulation |
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| 孙永珠: "谈谈中药软膏的制备", 《中国医院药学杂志》 * |
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Application publication date: 20220315 |