CN114164086A

CN114164086A - Liquid transfer platform for full-automatic liquid transfer workstation

Info

Publication number: CN114164086A
Application number: CN202111486881.9A
Authority: CN
Inventors: 朱中亚; 王迎枫
Original assignee: Jiangsu Lingkun Biotechnology Co ltd
Current assignee: Jiangsu Lingkun Biotechnology Co ltd
Priority date: 2021-12-07
Filing date: 2021-12-07
Publication date: 2022-03-11
Anticipated expiration: 2041-12-07
Also published as: CN114164086B

Abstract

The invention discloses a liquid transfer platform for a full-automatic liquid transfer workstation in the technical field of the full-automatic liquid transfer workstation, which comprises an installation platform, wherein fixed plates are arranged at the left end and the right end of the top of the installation platform, a top plate is commonly connected between the top ends of the two fixed plates, a guide rail is arranged at the bottom end of the top plate, an electric slider matched with the guide rail is slidably arranged on the guide rail, a movable plate is arranged at the bottom end of the electric slider, a moving mechanism and a liquid taking mechanism are arranged on the movable plate, the liquid transfer platform is arranged on the installation platform, an installation groove is formed in the surface of the left end of the top of the liquid transfer platform, sample boxes are arranged in the installation groove, a fixing mechanism is commonly connected between the two sample boxes, a DNA synthesizer is arranged at the right end of the top of the installation platform, and two symmetrical supporting legs are arranged at the bottom end of the installation platform, through setting up slide, gim peg and fixed establishment, be convenient for move the dismouting of liquid platform and sample box.

Description

Liquid transfer platform for full-automatic liquid transfer workstation

Technical Field

The invention relates to the technical field of full-automatic liquid transfer workstations, in particular to a liquid transfer platform for a full-automatic liquid transfer workstation.

Background

Along with the continuous development of social economy and scientific technology, the research objects faced by the pipetting work of laboratories such as biology, chemistry, environment, medicine research and development, food and the like, hospitals, blood stations and other units are more complex, the number of samples is increased along with the continuous increase, for example, the DAN synthesis technology, in the process of DNA synthesis, the pipetting work is usually carried out manually, the sample processing work of manual pipetting not only needs a large amount of manpower, material resources and time, but also is easy to generate pipetting errors, so that equipment capable of automatically realizing pipetting operation is needed, the existing full-automatic pipetting work station can meet the requirement, but most of the pipetting platforms used by the existing full-automatic pipetting work station are fixed and integrated structures, the structure is simple, the disassembly is inconvenient, the use efficiency is not high, and the sample boxes on the pipetting platform are not convenient to be quickly disassembled and assembled, so that the sample boxes are inconvenient to be cleaned or replaced in the later period, the use effect of moving liquid platform has been reduced for can improve the availability factor and the result of use that move liquid the platform, for this reason, we provide the full-automatic move liquid platform that moves liquid workstation and use.

Disclosure of Invention

The invention aims to provide a pipetting platform for a full-automatic pipetting workstation, which solves the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: the liquid transfer platform for the full-automatic liquid transfer workstation comprises an installation platform, wherein fixing plates are arranged at the left end and the right end of the top of the installation platform, a top plate is connected between the top ends of the two fixing plates, the bottom end of the top plate is provided with a guide rail, an electric slide block matched with the guide rail is arranged on the guide rail in a sliding way, a moving plate is arranged at the bottom end of the electric slide block, a moving mechanism and a liquid taking mechanism are arranged on the moving plate, a liquid transfer platform is arranged on the mounting platform and is positioned between the two fixing plates, the surface of the left end of the top of the liquid transfer platform is provided with a mounting groove, two sample boxes which are respectively arranged in the left and right directions are arranged in the mounting groove, a fixing mechanism is commonly connected between the two sample boxes, the DNA synthesizer is arranged at the right end of the top of the mounting table, and two symmetrical supporting legs are arranged at the bottom end of the mounting table.

Further, move liquid the platform all install at both ends about and be equipped with the slide, the slide is kept away from a side end sliding connection fixed plate that moves liquid the platform, set up the spout with slide looks adaptation on the fixed plate, the common screw thread through connection in junction of fixed plate and slide has the gim peg, the gim peg is located the fixed plate and keeps away from a side end that moves liquid the platform.

Furthermore, the fixing mechanism comprises a vertical plate, the front face of the vertical plate is in an inverted U shape, the vertical plate is arranged at the bottom end inside the mounting groove, two ends inside the vertical plate are rotatably inserted with the same transverse rod, a first bevel gear is fixedly sleeved on the surface of the middle of the outer end of the transverse rod, a second bevel gear is in transmission connection with the upper portion of the first bevel gear, an inserting rod is connected to the top end of the second bevel gear, the top end of the inserting rod is rotatably penetrated through the vertical plate and is connected with a rotating handle, a first screw rod is connected to each of the left end and the right end outside the transverse rod, the two first screw rods are opposite to each other, a movable threaded cylinder matched with the first screw rod is sleeved on the outer surface of the first screw rod far away from one side of the vertical plate in a threaded manner, a clamping plate is connected to the other end of the movable threaded cylinder, and one side surface of a sample box at the other end of the clamping plate is attached to each other.

Further, the distance between the two vertical plates and the inner walls of the left side and the right side of the mounting groove is the same, and the width of each vertical plate is the same as the inner width of the mounting groove.

Further, moving mechanism includes the mounting panel, the mounting panel installation is located electronic slider's bottom rear end, a side end installation that the mounting panel is close to the movable plate is equipped with the motor, one side output that the motor is close to the movable plate is connected with screw rod two, two screw threads through connection movable plates of screw rod just are connected with and end a plectane, set up the screw thread that leads to with screw rod two-phase adaptation on the movable plate and lead to the groove, the top installation of movable plate is equipped with two symmetrical rectangle sliders, the bottom of electronic slider is located in the slip of rectangle slider, set up the bar spout with rectangle slider looks adaptation on the electronic slider.

Further, get liquid mechanism and include that two are bilateral symmetry's electric telescopic handle respectively, two electric telescopic handle's bottom output is connected with the connecting plate jointly, the bottom installation of connecting plate is equipped with the syringe pump, the installation is equipped with a plurality of liquid suction pipes on the syringe pump, the liquid suction pipe is relative rather than one of them sample box.

Furthermore, a plurality of sample grooves distributed uniformly are formed in the two sample boxes, and test tubes matched with the sample grooves in the sample boxes close to the DNA synthesizer are inserted and connected in the sample grooves.

Furthermore, all install on the inside left and right sides end wall of mounting groove and be equipped with the protection pad, two one side end that the protection pad is close to mutually is laminated with one side end that two sample box kept away from mutually respectively mutually.

Compared with the prior art, the invention has the beneficial effects that:

1. through setting up slide and gim peg, through carrying out sliding connection between the spout on slide and the fixed plate, be convenient for will move the liquid platform and slide from the mount table and pull out or insert, can fix the slide installation on the fixed plate through the gim peg to can be fixed with moving the liquid platform installation, through the combined action of slide and gim peg, be convenient for carry out the dismouting to moving the liquid platform, be favorable to improving the availability factor of this device.

2. Through setting up fixed establishment, through the combined coordination through turning handle, horizontal pole, inserted bar, bevel gear one, bevel gear two, screw rod one, activity thread cylinder and cardboard, can realize the dismouting to the sample box, be favorable to improving the result of use of this device.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged schematic view of FIG. 1 at A;

FIG. 3 is an enlarged view of the structure of FIG. 1 at B;

FIG. 4 is a schematic structural diagram of the moving mechanism of the present invention;

FIG. 5 is a schematic diagram of the construction of two sample cartridges of the present invention;

in the figure: 1. an installation table; 2. a fixing plate; 3. a top plate; 4. a guide rail; 5. an electric slider; 6. moving the plate; 7. a moving mechanism; 71. mounting a plate; 72. a second screw; 73. a stop circular plate; 74. a rectangular slider; 75. a strip-shaped chute; 8. a liquid taking mechanism; 81. an electric telescopic rod; 82. a connecting plate; 83. an injection pump; 84. a liquid pumping pipe; 9. a pipetting platform; 10. installing a groove; 11. a sample cartridge; 12. a fixing mechanism; 121. a vertical plate; 122. a cross bar; 123. a first bevel gear; 124. a second bevel gear; 125. inserting a rod; 126. a first screw rod; 127. a movable threaded barrel; 128. clamping a plate; 13. a DNA synthesizer; 14. a slide plate; 15. a fixing bolt; 16. a sample tank; 17. a test tube; 18. a protective pad.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

Referring to fig. 1 and 4, a liquid transfer platform for a full-automatic liquid transfer workstation comprises an installation platform 1, wherein fixed plates 2 are installed at the left end and the right end of the top of the installation platform 1, a top plate 3 is connected between the top ends of the two fixed plates 2, a guide rail 4 is installed at the bottom end of the top plate 3, an electric slider 5 matched with the guide rail 4 is installed on the guide rail 4 in a sliding manner, a moving plate 6 is installed at the bottom end of the electric slider 5, the guide rail 4 and the electric slider 5 are both in the prior art, the moving plate 6 can move leftwards or rightwards conveniently by arranging the guide rail 4 and the electric slider 5, a moving mechanism 7 and a liquid taking mechanism 8 are installed on the moving plate 6, a liquid transfer platform 9 is installed on the installation platform 1, the liquid transfer platform 9 is positioned between the two fixed plates 2, an installation groove 10 is formed in the surface of the left end of the top of the liquid transfer platform 9, sample boxes 11 which are respectively arranged in the left-right direction are arranged in the installation groove 10, be connected with fixed establishment 12 between two sample box 11 jointly, the installation of the top right-hand member of mount table 1 is equipped with DNA synthesizer 13, and DNA synthesizer is prior art, through setting up DNA synthesizer, can carry out the DNA synthesis technique, and the bottom installation of mount table 1 is equipped with two symmetrical supporting legss.

Please refer to fig. 2, slide 14 is installed at both ends about pipetting platform 9, slide 14 is far away from one side end sliding connection fixed plate 2 of pipetting platform 9, set up the spout (not shown) with slide 14 looks adaptation on fixed plate 2, the common screw thread through connection in the junction of fixed plate 2 and slide 14 has gim peg 15, gim peg 15 is located one side end that fixed plate 2 is far away from pipetting platform 9, through setting up slide 14 and spout, it slides out to be convenient for pipette platform 9 slides in on mount table 1, through setting up gim peg 15, can fix slide 14 that is located the spout, prevent to pipette platform 9 and produce the aversion phenomenon on mount table 1, through slide 14, the combined action of spout and gim peg 15, be convenient for pipette platform 9's dismantlement and installation, be favorable to improving the availability factor of this device.

Referring to fig. 3, the fixing mechanism 12 includes a vertical plate 121, the front surface of the vertical plate 121 is in an inverted U shape, the vertical plate 121 is installed at the bottom end inside the installation groove 10, two ends inside the vertical plate 121 are rotatably inserted with a same cross rod 122, a first bevel gear 123 is fixedly sleeved on the middle surface of the outer end of the cross rod 122, a second bevel gear 124 is connected above the first bevel gear 123 in a transmission manner, the top end of the second bevel gear 124 is connected with an insertion rod 125, the top end of the insertion rod 125 rotatably penetrates through the vertical plate 121 and is connected with a rotating handle, a first screw 126 is connected to each of the left and right ends outside the cross rod 122, the two first screws 126 are opposite to each other, a movable threaded cylinder 127 matched with the first screw 126 is sleeved on the outer surface of one side of the first screw 126 away from the vertical plate 121, the other end of the movable threaded cylinder 127 is connected with a clamping plate 128, one side surface of the sample box 11 at the other end of the clamping plate 128 is attached to each other, by providing the fixing mechanism 12, and by the rotating handle, The cross rod 122, the inserted link 125, the first bevel gear 123, the second bevel gear 124, the first screw 126, the movable threaded cylinder 127 and the clamping plate 128 are cooperatively used, so that the sample box 11 can be disassembled and assembled, and the use effect of the device can be improved.

Referring to fig. 1, the two vertical plates 121 are respectively located at the same distance from the inner walls of the left side and the right side of the mounting groove 10, the width of the vertical plate 121 is the same as the inner width of the mounting groove 10, that is, the front end, the rear end and the bottom end of the vertical plate 121 are connected to the inner walls of the mounting groove 10, the liquid taking mechanism 8 includes two electric telescopic rods 81 respectively in bilateral symmetry, the bottom output ends of the two electric telescopic rods 81 are connected to a connecting plate 82, an injection pump 83 is installed at the bottom end of the connecting plate 82, the injection pump 83 is the prior art, a plurality of liquid taking pipes 84 are installed on the injection pump 83, the liquid taking pipes 84 are opposite to one of the sample boxes 11, and the liquid taking mechanism 8 is arranged to facilitate the liquid in the sample groove 16 to be taken.

Referring to fig. 1 and 4, the moving mechanism 7 includes a mounting plate 71, the mounting plate 71 is mounted at the rear end of the bottom of the electric slider 5, a motor is mounted at one side end of the mounting plate 71 close to the moving plate 6, a screw rod second 72 is connected to an output end of the motor close to the moving plate 6, the screw rod second 72 is in threaded through connection with the moving plate 6 and is connected with a stop circular plate 73, by setting the stop circular plate 73, the outer diameter of the stop circular plate 73 is larger than the diameter of the screw rod second 72, the moving plate 6 can be limited by the stop circular plate 73 to prevent the moving plate 6 from separating from the screw rod second 72, a threaded through groove adapted to the screw rod second 72 is formed on the moving plate 6, by setting the moving mechanism 7, through the combined action of the motor and the screw rod second 72, the moving plate 6 can move forward and backward, two symmetrical rectangular sliders 74 are mounted at the top end of the moving plate 6, the bottom of electronic slider 5 is located to rectangle slider 74 slip inlays, offers the bar spout 75 with rectangle slider 74 looks adaptation on the electronic slider 5, through setting up rectangle slider 74 and bar spout 75, through the sliding connection between rectangle slider 74 and the bar spout 75, is favorable to improving the stability when moving plate 6 removes.

Referring to fig. 1 and 5, a plurality of equally distributed sample slots 16 are formed in each of the two sample boxes 11, a test tube 17 adapted to the sample slots 16 is inserted into the sample slot 16 of the sample box 11 close to the DNA synthesizer 13, a liquid to be used can be injected into the sample slot 16 at the left end inside the mounting groove 10 by setting the sample slots 16, a test tube 17 adapted to the sample slot 16 at the right end inside the mounting groove 10 is inserted into the sample slot 16 at the right end inside the mounting groove 10, a liquid to be synthesized can be injected into the test tube 17 by setting the test tube 17, and the sample boxes are then mounted in the DNA synthesizer 13 for subsequent synthesis.

Example 2

Increased the protection pad 18 on embodiment 1's basis, please refer to fig. 1, all install on the inside left and right sides both ends wall of mounting groove 10 and be equipped with protection pad 18, the width and the height of protection pad 18 all are the same with the inside width and the height of mounting groove 10, protection pad 18 passes through viscose swing joint mounting groove 10, two protection pads 18 are close to a side end respectively with two sample box 11 side end laminating of keeping away from mutually, through setting up protection pad 18, can be when the fixed sample box 11 of centre gripping, prevent to produce collision friction between the inner wall of sample box 11 and mounting groove 10, can protect the external surface of sample box 11, be favorable to improving mounting groove 10's result of use.

The working principle is as follows: when the device is used, the device is connected with an external power supply, the handle is manually rotated in the forward direction, the inserted rod 125 and the bevel gear 124 can be driven to move in the forward direction in sequence, the bevel gear 123 in transmission connection with the bevel gear 124 can be driven to rotate in the reverse direction through the forward rotation of the bevel gear 124, the cross rod 122 can be driven to rotate in the reverse direction to drive the two screw rods 126 to synchronously move simultaneously, the movable threaded cylinders 127 in threaded connection with the screw rods 126 can be driven to be away from the vertical plate 121, the two clamping plates 128 can be driven to be away from each other through the mutual separation of the two movable threaded cylinders 127, the two sample boxes 11 can be respectively clamped and fixed at the left end and the right end in the mounting groove 10 through the two clamping plates 128, wherein the outer surface of the sample box 11 can be protected through the arrangement of the protective pads 18, and the steps are reversely operated, the sample box 11 can be taken out of the mounting groove 10, the sample box 11 can be conveniently and rapidly disassembled and assembled, so that the using effect of the device can be improved, the moving plate 6 can perform left-right reciprocating sliding motion through the electric slider 5, so that the moving mechanism 7 and the liquid taking mechanism 8 can be driven to perform synchronous motion in sequence, the screw rod II 72 can be driven to perform synchronous motion through forward rotation of the output end of the motor, so that the moving plate 6 in threaded connection with the screw rod II 72 can be driven to move backwards, wherein the stability of the moving plate 6 during motion can be favorably improved through the sliding action of the rectangular slider 74 and the strip-shaped sliding groove 75, so that the liquid taking mechanism 8 can be driven to move backwards, otherwise, the moving plate 6 and the liquid taking mechanism 8 can be driven to move forwards through reverse rotation of the output end of the motor, so that the required liquid is injected into the sample groove 16 on the sample box 11 at the left end inside the mounting groove 10, the liquid taking mechanism 8 can be driven to move downwards by moving the bottom output end of the electric telescopic rod 81 downwards, the liquid which is injected in advance in the sample groove 16 can be adsorbed by the liquid extracting pipe 84 by electrifying the injection pump 83 for air suction, the liquid extracting pipe 84 can be driven to be separated from the sample groove by moving the bottom output end of the electric telescopic rod 81 upwards, the movable plate 6 can be driven to move rightwards by sliding the electric slider 5 on the guide rail 4, when the liquid extracting pipe 84 is positioned right above one test tube 17, the moving work of the electric slider 5 is stopped, the liquid taking mechanism 8 can be driven to move downwards by moving the bottom output end of the electric telescopic rod 81 downwards until the liquid extracting pipe 84 is inserted into the test tube 17, the liquid in the liquid extracting pipe 84 can be dripped into the test tube 17 by blowing work through the injection pump 83 (the liquid extracting and draining work of the injection pump 83 are both the prior art), install test tube 17 and can carry out the synthetic work of the DNA of later stage on DNA synthesizer 13 next, carry out sliding connection between the spout on slide 14 and fixed plate 2, be convenient for slide pull out or insert move liquid platform 9 from the mount table, can fix the slide 14 installation on fixed plate 2 through gim peg 15, thereby can be with moving liquid platform 9 installation fixed, through the combined action of slide 14 and gim peg 15, be convenient for carry out the dismouting to moving liquid platform 9, be favorable to improving the availability factor of this device.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. Liquid-transfering platform that full-automatic liquid-transfering work station was used, including mount table (1), its characterized in that: the automatic liquid transferring device is characterized in that fixed plates (2) are installed at the left end and the right end of the top of the installation table (1), a top plate (3) is connected between the top ends of the two fixed plates (2) together, a guide rail (4) is installed at the bottom end of the top plate (3), an electric slider (5) matched with the guide rail is installed on the guide rail (4) in a sliding mode, a movable plate (6) is installed at the bottom end of the electric slider (5), a moving mechanism (7) and a liquid taking mechanism (8) are installed on the movable plate (6), a liquid transferring platform (9) is installed on the installation table (1), the liquid transferring platform (9) is located between the two fixed plates (2), an installation groove (10) is formed in the surface of the left end of the top of the liquid transferring platform (9), sample boxes (11) which are arranged in the left direction and the right direction respectively are arranged in the installation groove (10), and a fixing mechanism (12) is connected between the two sample boxes (11) together, the DNA synthesizer (13) is arranged at the right end of the top of the mounting table (1), and two symmetrical supporting legs are arranged at the bottom end of the mounting table (1).

2. A pipetting platform for a fully automatic pipetting station according to claim 1 characterised in that: move liquid platform (9) about both ends all install and be equipped with slide (14), slide (14) are kept away from a side end sliding connection fixed plate (2) that moves liquid platform (9), set up the spout with slide (14) looks adaptation on fixed plate (2), the common screw thread through connection in junction of fixed plate (2) and slide (14) has gim peg (15), gim peg (15) are located fixed plate (2) and keep away from a side end that moves liquid platform (9).

3. A pipetting platform for a fully automatic pipetting station according to claim 1 characterised in that: the fixing mechanism (12) comprises a vertical plate (121), the front surface of the vertical plate (121) is in an inverted U shape, the vertical plate (121) is arranged at the bottom end inside the mounting groove (10), two ends inside the vertical plate (121) are rotatably inserted with a cross rod (122), a first bevel gear (123) is fixedly sleeved on the surface of the middle part of the outer end of the cross rod (122), a second bevel gear (124) is connected above the first bevel gear (123) in a transmission manner, the top end of the second bevel gear (124) is connected with an inserting rod (125), the top end of the inserting rod (125) rotatably penetrates through the vertical plate (121) and is connected with a rotating handle, the left end and the right end outside the cross rod (122) are respectively connected with a first screw rod (126), the two first screw rods (126) are opposite, and a movable threaded barrel (127) matched with the first screw rods (126) is sleeved on the outer surface of one side, far away from the vertical plate (121), of the first screw rods (126), the other end of the movable threaded cylinder (127) is connected with a clamping plate (128), and the surface of one side of the sample box (11) at the other end of the clamping plate (128) is attached.

4. A pipetting platform for a fully automatic pipetting station according to claim 3 characterised in that: the distances between the two vertical plates (121) and the inner walls of the left side and the right side of the mounting groove (10) are the same, and the width of each vertical plate (121) is the same as the inner width of the mounting groove (10).

5. A pipetting platform for a fully automatic pipetting station according to claim 1 characterised in that: moving mechanism (7) include mounting panel (71), mounting panel (71) installation is located the bottom rear end of electronic slider (5), mounting panel (71) are close to one side end installation of moving plate (6) and are equipped with the motor, one side output that the motor is close to moving plate (6) is connected with two (72) of screw rod, two (72) screw threads through connection moving plate (6) and be connected with end position plectane (73), set up the screw thread that matches with two (72) of screw rod on moving plate (6) and lead to the groove, the top installation of moving plate (6) is equipped with two symmetrical rectangle slider (74), rectangle slider (74) slide to inlay the bottom of locating electronic slider (5), set up bar spout (75) with rectangle slider (74) looks adaptation on electronic slider (5).

6. A pipetting platform for a fully automatic pipetting station according to claim 1 characterised in that: get liquid mechanism (8) and include that two are bilateral symmetry's electric telescopic handle (81) respectively, two the bottom output of electric telescopic handle (81) is connected with connecting plate (82) jointly, the bottom installation of connecting plate (82) is equipped with syringe pump (83), the installation is equipped with a plurality of liquid suction pipes (84) on syringe pump (83), liquid suction pipe (84) are mutually opposite rather than one of them sample box (11).

7. A pipetting platform for a fully automatic pipetting station according to claim 1 characterised in that: a plurality of equally distributed sample grooves (16) are formed in the two sample boxes (11), and test tubes (17) matched with the sample grooves (16) are inserted into the sample grooves (16) in the sample boxes (11) close to the DNA synthesizer (13).

8. A pipetting platform for a fully automatic pipetting station according to claim 1 characterised in that: all install on the inside left and right sides both ends wall of mounting groove (10) and be equipped with protection pad (18), two one side end that protection pad (18) are close to mutually is laminated with one side end that two sample box (11) kept away from mutually respectively mutually.