CN212083464U - Electric liquid transfer equipment - Google Patents

Electric liquid transfer equipment Download PDF

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Publication number
CN212083464U
CN212083464U CN202020731929.2U CN202020731929U CN212083464U CN 212083464 U CN212083464 U CN 212083464U CN 202020731929 U CN202020731929 U CN 202020731929U CN 212083464 U CN212083464 U CN 212083464U
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electric
motor
pipettors
pipetting
central transverse
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范光伟
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Premedical Laboratories Co ltd
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Premedical Laboratories Co ltd
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Abstract

The utility model provides an electric liquid transfer device, which comprises two sliding tables symmetrically arranged at two opposite sides of a central transverse shaft, wherein each sliding table is provided with at least one electric liquid transfer device; each electric pipettor comprises a loading mechanism and an executing mechanism, wherein the loading mechanism comprises a supporting frame and a first motor, the executing mechanism comprises a rack, a second motor and a pipetting assembly, the pipetting assembly is positioned at the position of a central transverse shaft, the second motor is positioned on the outer side of the central transverse shaft, and the first motor is positioned on the outer side of a fulcrum; when the electric pipettors on the two sliding tables are gathered side by side, the liquid-transfering assemblies of the electric pipettors on the two sliding tables are sequentially and alternately arranged along the central transverse shaft at the central transverse shaft. The utility model discloses under the prerequisite that satisfies household utensils basic centre-to-centre spacing requirement, adopt ordinary motor to the plumb line distance is the shortest between realization actuating mechanism's reciprocating motion axis and the fulcrum, reduces because the harmful overturning moment and the fatigue deformation that produce when actuating mechanism frequently carries out the press-in connection along its axis downwards with move the liquid head.

Description

Electric liquid transfer equipment
Technical Field
The utility model relates to a sample adding equipment, especially an electronic liquid moving equipment.
Background
In the detection work in the fields of medicine, food, biology and the like, a lot of pretreatment work needs to be carried out on biological materials and samples (generally in liquid state), and the operations such as liquid transfer, sample adding, mixing and the like and the preparation of templates of a large amount of biological detection materials can be completed in batches in a short time by adopting a high-throughput automatic biological sample treatment system.
The electric pipettor is a core technical unit in an automatic biological sample processing system. When the electric pipettors are used in combination, the working objects are the standardized vessel restrictions of different purposes, and the distance between the movement axis of any one pipettor and the movement axis of the side pipettor must meet the requirement of the basic center distance of the conventional vessel, and is generally 9 mm. When the liquid transfer device is combined and applied, the structure space is extremely narrow, and various mechanical parts, motors, sensors for various purposes and other components are also arranged in the liquid transfer actuating mechanism which is narrow.
According to different suction driving methods of the electric pipettor for liquid, the electric pipettor is divided into two types: gas-liquid mixing displacement type and gas displacement type.
The gas-liquid mixing displacement type pipettor adopts a liquid plunger, and the liquid plunger and sample liquid are isolated by an air gap reserved in a pipetting head, and the gas-liquid mixing displacement type pipettor has the advantages that an electric reciprocating motion injection mechanism, a pressure sensor and the like are separated, only one thin guide pipe enters a pipetting execution mechanism, so that the design pressure and load of a pipetting execution mechanism assembly are greatly reduced, and the requirement of the minimum center distance of a vessel is met; meanwhile, the distance between the reciprocating axis of the pipetting actuating mechanism and the perpendicular line of the mechanism pivot can be minimized, and the harmful overturning moment and the fatigue deformation of a supporting component generated when the pipetting actuating mechanism is connected with the pipetting head in a pressing-in manner frequently along the axis of the pipetting actuating mechanism; and because the separation air gap between the liquid plunger and the sample liquid is very small, the pipetting precision is high. The defects of the existing gas-liquid pipeline pressure system, more components, complex debugging and high maintenance cost; when the room temperature is low, liquid leakage is likely to occur.
The gas displacement type pipettor adopts a solid plunger, the reciprocating motion of the solid plunger is realized by a motor through a coupling or other connecting parts to drive a screw rod or a synchronous toothed belt, namely, components such as an electric reciprocating motion injection mechanism, a pressure sensor and the like are assembled with a pipetting executing mechanism to form an independent module, so that the liquid displacement type pipettor can be used independently, and a powerful multi-module parallel liquid treatment system can be assembled without complex pressure pipelines and pump systems, has clear structural hierarchy, and greatly reduces the workload of unit structure installation and debugging.
In order to meet the requirement of minimum center distance of vessels, the current gas displacement type pipettors have two structural settings: firstly, a blade type pipetting actuating mechanism unit is formed by a motor with a small diameter and a high rotating speed and a speed reducer, although the motor can meet the requirement of the minimum center distance of a vessel and realize the shortest distance between the reciprocating motion axis of the pipetting actuating mechanism and the vertical line of the mechanism fulcrum, the motor is extremely expensive, the transportation and maintenance cost is high, and the debugging difficulty is large; and secondly, the structural layout is changed, the conventional motor and the matched motion controller are used, although the maintenance cost of the installation operation can be greatly reduced, in order to meet the requirement of staggered distribution of the rear wide body pipetting actuating mechanism components using the conventional motor, the distance between the reciprocating motion axis of the pipetting actuating mechanism and the perpendicular line of the mechanism fulcrum is increased, and the harmful overturning moment and the fatigue deformation factor of the supporting component generated when the pipetting actuating mechanism is downwards connected with the pipetting head in a press-in manner along the axis of the pipetting actuating mechanism are increased.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing an electronic liquid-transfering equipment, it is satisfying under the prerequisite that household utensils basic centre-to-centre spacing required, can solve the expensive problem that prior art adopted the high rotational speed motor of minor diameter to exist, can solve again that prior art adopts the liquid-transfering actuating mechanism reciprocating motion axis that conventional motor exists big with mechanism fulcrum plumb line distance, move liquid actuating mechanism along the axis downwards with move the liquid head frequently press into the big and fatigue deformation problem of harmful overturning moment that produces when being connected.
In order to achieve the above object, the present invention provides an electric liquid transfer apparatus, which includes two sliding tables symmetrically disposed on opposite sides of a central cross shaft, the two sliding tables being parallel to the central cross shaft, each sliding table being provided with at least one electric liquid transfer device; every electronic pipettor includes loading mechanism and actuating mechanism, loading mechanism including can transversely slide ground with the support frame that the slip table is connected with fix first motor on the support frame, the support frame with the junction of slip table is the fulcrum of electronic pipettor, actuating mechanism including can slide from top to bottom with the frame that the support frame is connected, fix second motor in the frame and move the liquid subassembly, move the liquid subassembly include with the syringe that the frame is connected with vertically insert locate the plunger in the syringe, first motor with the frame is connected and can drive the frame drives the syringe slides from top to bottom for the support frame, the syringe is through the lapse and move the liquid head grafting, the second motor with the plunger is connected and can drive the plunger is in reciprocate in the syringe in order to inhale and discharge liquid, the pipetting assembly is positioned at the central transverse shaft, the second motor is positioned at the outer side of the central transverse shaft and at the inner side of the fulcrum, and the first motor is positioned at the outer side of the fulcrum; when the electric pipettors on the two sliding tables are gathered side by side, the liquid-transferring assemblies of the electric pipettors on the two sliding tables are sequentially and alternately arranged on the central transverse shaft along the central transverse shaft.
The electric pipetting device as described above, wherein the central axis of the pipetting assembly passes through the central transverse axis and is perpendicular to the central transverse axis, and when the electric pipettes on the two sliding tables are gathered side by side, the center distance between the two adjacent pipetting assemblies is not greater than 9 mm.
The electric pipetting device comprises a plurality of electric pipettors, wherein each sliding table is provided with a plurality of electric pipettors, when the electric pipettors on the two sliding tables are gathered side by side, the center distance between two adjacent pipetting assemblies is smaller than the center distance between two adjacent first motors on the same sliding table, and the center distance between two adjacent pipetting assemblies is smaller than the center distance between two adjacent second motors on the same sliding table.
The electric liquid transfer equipment comprises a central cross shaft, wherein each sliding table is provided with a plurality of electric pipettors, two sliding tables are respectively a first sliding table and a second sliding table, each electric pipettor on the first sliding table is a first electric pipettor, each electric pipettor on the second sliding table is a second electric pipettor, when the electric pipettors on the two sliding tables are gathered side by side, the plurality of first electric pipettors and the plurality of second electric pipettors are respectively arranged on two opposite sides of the central cross shaft in sequence along the direction parallel to the central cross shaft, and the plurality of first electric pipettors and the plurality of second electric pipettors are staggered in sequence along the direction parallel to the central cross shaft; the first motors of the plurality of first electric pipettors and the first motors of the plurality of second electric pipettors are respectively arranged side by side in sequence on two opposite sides of the central transverse shaft along the direction parallel to the central transverse shaft, and the first motors of the plurality of first electric pipettors and the first motors of the plurality of second electric pipettors are sequentially staggered in the direction parallel to the central transverse shaft; the second motors of the first electric pipettors and the second motors of the second electric pipettors are respectively arranged on two opposite sides of the central transverse shaft side by side in sequence along the direction parallel to the central transverse shaft, and the second motors of the first electric pipettors and the second motors of the second electric pipettors are staggered in sequence in the direction parallel to the central transverse shaft.
The electric pipetting device comprises two sliding table guide rails, wherein each sliding table comprises two sliding table guide rails, the sliding table guide rails are parallel to a central cross shaft, the two sliding table guide rails are arranged at intervals from top to bottom, a supporting slide block is fixed on the supporting frame and is in sliding connection with the sliding table guide rails, the joint of the supporting slide block and the sliding table guide rails is a fulcrum, and the supporting slide block is located at the same position on the sliding table, is arbitrarily adjacent to the sliding table, and is spaced in the vertical direction and is in sliding connection with the sliding table guide rails respectively.
The electric liquid-transfering equipment as above, wherein, the length of supporting slider is greater than the width of support frame, supporting slider has the width direction epirelief of support frame the bulge of support frame, every be equipped with on the support frame of electric pipettor and be used for dodging the recess of dodging of the bulge of the supporting slider of adjacent another electric pipettor, when being located same two adjacent electric pipettors on the slip table are gathered together side by side, one of them the bulge of the supporting slider of electric pipettor stretches into another in the recess is dodged of electric pipettor.
The electric pipetting device comprises two fixing screw rods, wherein each sliding table comprises two fixing screw rods, the fixing screw rods are parallel to the central cross shaft, the two fixing screw rods are arranged at intervals from top to bottom, a feed-through motor for the fixing screw rods to penetrate through is fixed on the supporting frame, the feed-through motor is positioned on the outer side of the supporting point, a first anti-backlash nut used for being in threaded connection with the fixing screw rods is arranged inside the feed-through motor, the first anti-backlash nut can be driven by a rotor of the feed-through motor to rotate, the feed-through motor is arranged on the first anti-backlash nut and rotates relative to the fixing screw rods, the fixing screw rods slide, and any two adjacent feed-through motors of the electric pipettors are spaced in the vertical direction and are respectively in threaded connection with the two fixing screw rods.
The electric pipetting device comprises a support frame, a loading mechanism, a first motor, a second motor, a driving pulley, a second motor and a second screw rod, wherein the loading mechanism further comprises a first screw rod which is vertically arranged on the support frame in a rotatable manner and is positioned on the inner side of the fulcrum, the driven pulley is connected above the first screw rod, the driving pulley is connected with the driven pulley through a horizontally arranged synchronous belt and is positioned on the outer side of the fulcrum, the first motor is coaxially connected with the driving pulley, the first motor can drive the first screw rod to rotate through the driving pulley, the synchronous belt and the driven pulley in sequence, and the first screw rod drives the rack to slide up and down relative to the support frame through rotation; the actuating mechanism is located the fulcrum is inboard, move the liquid subassembly still including locating the syringe top and with the dislocation slider that the plunger is connected, actuating mechanism still including can rotate ground vertical installation in the frame and with dislocation slider threaded connection's second screw rod, the second motor is located second screw rod top and with the second screw rod is connected, the second motor can drive the second screw rod rotates, the second screw rod is through rotating the drive dislocation slider drives the plunger reciprocates, the plunger is through reciprocating and inhaling or discharging liquid the liquid head.
The electric liquid-transfering equipment as above, wherein, the support frame includes the roof, driven pulley installs the top of roof, the roof court the outside extension of fulcrum forms the extension board, the width of extension board is greater than the width of roof, driving pulley installs the top of extension board, first motor is invertedly fixed the bottom of extension board, the roof with extension board constitution a backup pad, when two when electric pipettes on the slip table gather together side by side, be located same a plurality of on the slip table electric pipettes' backup pad splices in proper order and makes up into the flat board.
The electric pipetting device comprises a frame, a plunger, an injection head, a plunger, a sampling tube, an electric pipetting device and an execution mechanism, wherein the lower end of the injection tube is provided with an insertion wall capable of being inserted into the pipetting head, the side wall of the injection tube is adjacent to the insertion wall, a through hole is formed in the position above the insertion wall and below the plunger, the execution mechanism further comprises a pressure detection device, the pressure detection device comprises the sampling tube and a pressure sensor arranged on the frame, one end of the sampling tube is inserted into the through hole and communicated with the injection tube, and the other end of the sampling tube is connected with the pressure sensor.
The utility model discloses an electronic pipetting equipment's characteristics and advantage are:
1. the utility model discloses an electronic liquid-transfering equipment, the first motor and the second motor that electronic pipettor adopted are ordinary motors, but the motor of the high rotational speed of minor diameter area speed reducer, the price is low, because the size of ordinary motor is great, when arranging, place the first motor in the outside of fulcrum, therefore the first motor can not occupy the space between the reciprocating motion axis of actuating mechanism and the fulcrum, can realize that the perpendicular line distance between the reciprocating motion axis of actuating mechanism and the fulcrum is the minimizing, thereby reduce because the actuating mechanism along its axis down with move the liquid head frequently press into harmful overturning moment and the fatigue deformation that produce when going into the connection;
2. the utility model discloses an electronic liquid-transfering equipment, through arranging the liquid-transfering component of electronic pipettor in the inboard center cross axle department of two slip tables, arrange the great first motor of size and second motor in the outside of center cross axle, when all electronic pipettors on two slip tables are gathered together side by side, the liquid-transfering component of all electronic pipettors is arranged along center cross axle in proper order in turn, the centre-to-centre spacing between two adjacent liquid-transfering components only depends on the width of liquid-transfering component self, do not receive the influence of the great first motor of size and second motor completely, can realize the minimizing of centre-to-centre spacing between the adjacent liquid-transfering components, satisfy the basic centre-to-centre spacing requirement of conventional;
3. the utility model discloses an electronic pipetting equipment, the reciprocating motion of electronic pipettor along slip table guide rail relies on the rotation realization of the built-in first anti-backlash nut of the inside rotor of punching motor, not only start and stop steadily, and mechanical shock is little, programme-controlled position is accurate simultaneously, easily calibration, a plurality of electronic pipettors on the slip table can synchronous operation under the equidistance instruction, also can non-equidistance asynchronous operation, that is to say, each electronic pipettor all has the ability of independent work under different liquid-transfering parameters, can adapt to respective household utensils and move liquid parameter setting simultaneously respectively, make electronic pipetting equipment can be competent in the very high automation liquid handling work of complexity;
4. the utility model discloses an electronic liquid-transfering equipment, through installing four at least electronic pipettors on every slip table, just also connect two punching motors on every clamping screw at least, by the coaxial reciprocating motion of the punching motor more than two on every super slender clamping screw, each other is for supporting, has not only effectively prevented super slender clamping screw's shake stagnation, has simplified mechanism and part cost simultaneously.
Drawings
The drawings are only intended to illustrate and explain the present invention and do not limit the scope of the invention. Wherein:
fig. 1 is a schematic view of an electric pipette device according to an embodiment of the present invention in a side-by-side gathered state;
FIG. 2 is a schematic perspective view of FIG. 1;
fig. 3 is a schematic view of an electric pipetting apparatus according to an embodiment of the present invention in a dispersed state;
FIG. 4 is a schematic perspective view of FIG. 3;
fig. 5 is a front view of an embodiment of a medium electric pipette of the present invention;
FIG. 6 is a cross-sectional view of the actuator of FIG. 5;
fig. 7 is a perspective view of the electric pipette of fig. 5.
Main element number description:
1. an electric pipettor;
100. a loading mechanism;
101. a support frame; 1011. a connecting plate; 1012. a top plate; 1013. a base plate; 1014. an extension plate;
102. a first screw; 103. a driven pulley; 104. a synchronous belt;
105. a driving pulley; 106. a first motor; 107. a guide rail; 108. a reference position sensor;
109. a fulcrum;
200. an actuator;
201. a frame; 2011. a top frame; 2012. a chassis; 2013. a side plate; 2014. mounting grooves;
2015. a through hole; 2016. a wire slot; 2017. a sliding space;
202. an injection tube; 2021. a plug-in wall; 2022. perforating; 2023. an annular projection;
2024. an O-shaped sealing ring;
203. a plunger; 204. a staggered slide block; 205. a second screw;
206. a second motor; 207. a buffer; 208. a sampling tube; 209. briquetting; 210. a top rod;
211. an elastic member; 212. an adjusting ring; 213. a first jackscrew; 214. a second jackscrew; 215. a first baffle plate;
216. a signal conditioning board; 217. a second baffle plate; 218. an optical axis; 219. a connecting rod; 220. a ball head;
221. a rubber plug; 222. adjusting the nut; 223. an O-shaped sealing ring; 224. a hollow flange;
225. a guide rail slider; 226. a nut slider; 227. a second anti-backlash nut; 228. a motor flange;
229. a support slide block; 230. a pipetting assembly;
300. a pipetting head; 400. a feed-through motor;
2. a sliding table; 21. a substrate; 22. a sliding table guide rail; 23. fixing the screw rod; 24. a screw supporting end block;
25. the screw locks the end block.
Detailed Description
In order to clearly understand the technical features, objects, and effects of the present invention, embodiments of the present invention will be described with reference to the accompanying drawings. Where adjective or adverbial modifiers "upper" and "lower", "top" and "bottom", "inner" and "outer", "lateral" and "longitudinal", "front" and "rear" are used merely to facilitate relative reference between groups of terms, and do not describe any particular directional limitation on the modified terms. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated, whereby a feature defined as "first", "second", etc. may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
Unless the directions indicated are individually defined, the "inner side" referred to herein is the side of the central cross axis shown in fig. 1 of the present invention, and the "outer side" is the side of the central cross axis shown in fig. 1 of the present invention, and the "lateral" referred to herein is based on the direction of the central cross axis shown in fig. 1 of the present invention, and the "up", "down", "vertical", "horizontal" and the like are all based on the directions of the upper, lower, vertical, horizontal and the like shown in fig. 5 of the present invention, and are herein collectively described.
As shown in fig. 1, fig. 2, fig. 3, fig. 4, and fig. 5, the present invention provides an electric pipetting apparatus, which includes an electric pipettor 1 and two sliding tables 2 symmetrically disposed on opposite sides of a central horizontal axis X, where the two sliding tables 2 are parallel to the central horizontal axis X, each sliding table 2 is provided with at least one electric pipettor 1, and the electric pipettor 1 is a gas displacement pipettor;
each electric pipettor 1 comprises a loading mechanism 100 for loading a pipetting head 300 and an executing mechanism 200 for sucking and discharging liquid, the pipetting head 300 is a standardized pipetting head with a volume of 50-1000 microliters, the pipetting head 300 is a disposable article, is usually made of plastic and belongs to a consumable, and is discarded after one-time liquid treatment;
wherein, the loading mechanism 100 comprises a support frame 101 which can be connected with the sliding table 2 in a transverse sliding manner and a first motor 106 which is fixed on the support frame 101, the joint of the support frame 101 and the sliding table 2 is a fulcrum 109 of the electric pipettor 1, the executing mechanism 200 comprises a rack 201 which can be connected with the support frame 101 in a vertical sliding manner, a second motor 206 which is fixed on the rack 201, and a pipetting assembly 230, the pipetting assembly 230 comprises a syringe 202 which is connected with the rack 201 and a plunger 203 which is vertically inserted in the syringe 202, an injection cavity is formed in the syringe 202, the first motor 106 is connected with the rack 201 and can drive the rack 201 to slide up and down relative to the support frame 101, the rack 201 drives the syringe 202 to move down when sliding down, so that the syringe 202 is inserted in the pipetting head 300 which is arranged below the syringe 202, thereby loading the pipetting head 300 is realized, the second motor 206 is connected with the plunger 203 and can drive the plunger 203 to move, so that the plunger 203 sucks or discharges liquid into or out of the pipetting head 300 to realize liquid sucking and discharging, the pipetting assembly 230 is positioned at the central horizontal axis X, the second motor 206 is positioned outside the central horizontal axis X and inside the fulcrum 109, the first motor 106 is positioned outside the fulcrum 109, namely, the pipetting assembly 230, the second motor 206, the fulcrum 109 and the first motor 106 are arranged in sequence from the central horizontal axis X to the outside; when the electric pipettors 1 on the two sliding tables 2 are gathered side by side, the pipetting assemblies 230 of all the electric pipettors 1 on the two sliding tables 2 are sequentially and alternately arranged along the central transverse axis X at the central transverse axis X.
The utility model discloses an electronic liquid-transfering equipment, the first motor 106 and the second motor 206 that electronic pipettor 1 adopted are ordinary motors (being conventional motors), but the motor of the high rotational speed area speed reducer of minor diameter, the price is low, because the size of ordinary motor is great, when arranging, arrange first motor 106 in the outside of fulcrum 109, therefore first motor 106 can not occupy the space between the reciprocating motion axis of actuating mechanism 200 and fulcrum 109, can realize that the perpendicular line distance between the reciprocating motion axis of actuating mechanism 200 and fulcrum 109 is the minimizing, thereby reduce because actuating mechanism 200 along its axis down with move liquid head 300 frequently carry out the harmful overturning moment and the fatigue deformation that produce when pressing into and being connected;
in addition, by placing the pipetting assemblies 230 of the electric pipettors 1 at the middle positions of the inner sides of the two sliding tables 2 (i.e. at the central horizontal axis X), placing the first motor 106 and the second motor 206 with larger sizes at the outer sides of the central horizontal axis X, when all the electric pipettors 1 on the two sliding tables 2 are gathered side by side, the pipetting assemblies 230 of all the electric pipettors 1 are sequentially and alternately arranged along the central horizontal axis X, the center distance between two adjacent pipetting assemblies 230 only depends on the width of the pipetting assembly 230, and is completely not affected by the first motor 106 and the second motor 206 with larger sizes, so that the center distance between the adjacent pipetting assemblies 230 can be minimized, and the requirement of the basic center distance of a conventional vessel can be met;
in addition, because the injection tube 202 can be directly inserted with the pipetting head 300, the injection pump and the injection cavity are combined into a whole, the structure is simple and compact, and the injection tube 202 and the plunger 203 are lengthened, so that the range is enlarged.
When adopting the utility model discloses an electronic liquid-transfering equipment moves liquid the time, puts the household utensils in the below of electronic pipettor 1, according to household utensils centre-to-centre spacing, adjusts the position of each electronic pipettor 1 on slip table 2, makes two adjacent centre-to-centre spacings that move liquid subassembly 230 equal household utensils centre-to-centre spacing, can carry out batch liquid-transfering operation.
As shown in fig. 1 and fig. 2, further, the central axis of the pipetting assembly 230 passes through the central transverse axis X and is perpendicular to the central transverse axis X, that is, the central axis of the pipetting assembly 230 and the central transverse axis X are located on the same vertical plane, when the electric pipettors 1 on the two sliding tables 2 are gathered side by side, the center distance between two adjacent pipetting assemblies 230 is not greater than 9mm, and the requirement of the basic center distance of the conventional vessel is met.
As shown in fig. 1 and 2, further, each sliding table 2 is mounted with a plurality of electric pipettors, because the width of the first motor 106 and the width of the second motor 206 are both greater than the width of the pipette assembly 230, when the electric pipettors 1 on two sliding tables 2 are gathered together side by side, the center distance between two adjacent pipette assemblies 230 is smaller than the center distance between the first motors 106 of two adjacent electric pipettors 1 on the same sliding table 2, and the center distance between two adjacent pipette assemblies 230 is smaller than the center distance between the second motors 206 of two adjacent electric pipettors 1 on the same sliding table 2.
As shown in fig. 1 and fig. 2, for convenience of description, the two sliding tables 2 are respectively referred to as a first sliding table and a second sliding table, the electric pipettes 1 on the first sliding table are referred to as first electric pipettes, the electric pipettes 1 on the second sliding table are referred to as second electric pipettes, when the electric pipettes 1 on the two sliding tables 2 are gathered side by side, the plurality of first electric pipettes and the plurality of second electric pipettes are respectively and sequentially arranged side by side along a direction parallel to the central transverse axis X on opposite sides of the central transverse axis X, the plurality of pipette components 230 of the first electric pipettes and the plurality of pipette components 230 of the second electric pipettes are sequentially and alternately arranged along the central transverse axis X on the central transverse axis X, that is, the pipette components 230 of all the electric pipettes 1 of the electric pipetting device are arranged in a straight line along the central transverse axis X, and the plurality of second motors 206 of the first electric pipettes and the plurality of second electric pipettes are arranged along a direction parallel to the central transverse axis The two rows of second motors 206 respectively positioned on two opposite sides of the central transverse axis X are formed by sequentially arranging the first motors 106 of the plurality of first electric pipettors and the first motors 106 of the plurality of second electric pipettors side by side along a direction parallel to the central transverse axis X on two opposite sides of the central transverse axis X, so that two rows of first motors 106 respectively positioned on two opposite sides of the central transverse axis X are formed, and the two rows of first motors 106 are positioned on the outer sides of the two rows of second motors 206.
As shown in fig. 1 and 2, further, since the width of the first motor 106 and the width of the second motor 206 are both greater than the width of the pipetting assembly 230, when the electric pipettors 1 on the two sliding tables 2 are gathered side by side, the plurality of first electric pipettors and the plurality of second electric pipettors are sequentially displaced in the direction parallel to the central horizontal axis X, and the plurality of first electric pipettors and the plurality of second.
As shown in fig. 1, 2, 3, and 4, in a specific embodiment, each slide table 2 includes a base material 21 and two slide table guide rails 22, the slide table guide rails 22 are fixed inside the base material 21, the slide table guide rails 22 are parallel to the central horizontal axis X, the two slide table guide rails 22 are arranged at intervals up and down, a support slider 229 is fixed on one side of the support frame 101 opposite to the central horizontal axis X, for example, a support slider 229 is fixed on the back side of the support frame 101 opposite to the central horizontal axis X, the support slider 229 is slidably connected with the slide table guide rails 22, the support slider 229 can slide along the slide table guide rails 22, a joint between the support slider 229 and the slide table guide rail 22 is a fulcrum 109 of the electric pipette 1, the support slider 229 of any two adjacent electric pipette 1 on the same slide table 2 is vertically spaced and slidably connected with the two slide table guide rails 22, that is, the support sliders 229 of two adjacent electric pipette 1 are slidably connected with different, the support blocks 229 of two adjacent electric pipettors 1 are disposed in a vertically staggered manner, so as to prevent interference between the support blocks 229 of two adjacent electric pipettors 1.
For example, the support block 229 is provided with a groove facing the slide rail 22 and engaging with the slide rail 22, and the sectional shape of the groove is the same as that of the slide rail 22, and the support block 229 is slidably engaged with the outside of the slide rail 22 through the groove.
As shown in fig. 1 and 2, further, the length of the support block 229 is greater than the width of the support frame 101, so that the support frame 101 slides smoothly along the slide table guide 22, the support block 229 has a protruding portion protruding out of the support frame 101 in the width direction of the support frame 101, an avoiding groove for avoiding the protruding portion of the support block 229 of another adjacent electric pipette 1 is provided on the support frame 101 of each electric pipette 1, when two adjacent electric pipettors 1 on the same slide table 2 are gathered side by side, the protruding portion of the support block 229 of one electric pipette 1 extends into the avoiding groove of another electric pipette 1, so as to avoid interference with the adjacent support frame 101 due to the longer length of the support block 229, and if the support block 229 interferes with the adjacent support frame 101, the lateral distance between the support frame 101 where the support block 229 is located and the adjacent other support frame 101 is increased, further, the center distance between the adjacent pipetting assemblies 230 is increased, so that the center distance between the pipetting assemblies 230 can be prevented from being influenced by the support block 229 by providing an avoiding groove, which helps to minimize the center distance between the adjacent pipetting assemblies 230.
Further, the base material 21 is a strip-shaped section, the base material 21 is parallel to the central horizontal axis X, and the inside of the base material 21 is hollowed out to reduce the weight.
As shown in fig. 2 and 4, in a specific embodiment, each sliding table 2 includes two fixed screws 23, one of the fixed screws 23 is fixed above the substrate 21, the other fixed screw 23 is fixed below the substrate 21, that is, the fixed screw 23 neither rotates nor moves axially, the fixed screw 23 is parallel to the central horizontal axis X, the two fixed screws 23 are arranged at intervals up and down, a penetrating motor 400 for the fixed screw 23 to pass through is fixed on a side of the supporting frame 101 opposite to the central horizontal axis X, the penetrating motor 400 is located outside the supporting point 109, for example, the penetrating motor 400 is located right below the first motor 106, the penetrating motor 400 is provided with an encoder, a first anti-backlash nut for threaded connection with the fixed screw 23 is arranged inside the penetrating motor 400, the first anti-backlash nut can rotate under the driving of a rotor of the penetrating motor 400, and since the fixed screw 23 can neither rotate nor move axially, when the first gap eliminating nut rotates, the first gap eliminating nut simultaneously drives the piercing motor 400 to move along the fixing screw 23, namely, the whole electric pipettor 1 is driven to move along the fixing screw 23, the piercing motors 400 of any two adjacent electric pipettors 1 are spaced in the vertical direction and are respectively in threaded connection with the two fixing screws 23, namely, the piercing motors 400 of the two adjacent electric pipettors 1 are respectively connected with different fixing screws 23, and the piercing motors 400 of the two adjacent electric pipettors 1 are arranged in a vertically staggered manner so as to avoid interference between the piercing motors 400 of the two adjacent electric pipettors 1.
As shown in fig. 2 and 4, specifically, a motor flange 228 is fixed on the back surface of the support frame 101 facing away from the central horizontal axis X, the motor flange 228 extends towards the outside of the support frame 101 and is perpendicular to the back surface of the support frame 101, the end surface of the feedthrough motor 400 is abutted against and fixed to the end surface of the motor flange 228, a gap is formed between the feedthrough motor 400 and the back surface of the support frame 101, because the length of the feedthrough motor 400 is greater than the width of the support frame 101, the feedthrough motor 400 has a protruding portion protruding out of the support frame 101 in the width direction of the support frame 101, when two adjacent electric pipettors 1 on the same slide table 2 are gathered together side by side, the protruding portion of the feedthrough motor 400 of one electric pipettor 1 is located on the outside (i.e. behind) the other electric pipettor 1, because a gap is also formed between the protruding portion of the feedthrough motor 400 and the back surface of the, interference can not occur, so that an avoiding groove is not required to be arranged; a screw supporting end block 24 and a screw locking end block 25 are fixed to both ends of the base material 21 to fix both ends of the fixing screw 23, respectively.
In the present embodiment, the piercing motor 400 is disposed outside the fulcrum 109, so that the piercing motor 400 does not occupy a space between the reciprocating axis of the actuator 200 and the fulcrum 109, thereby contributing to the minimization of the perpendicular distance between the reciprocating axis of the actuator 200 and the fulcrum 109.
In this embodiment, the reciprocating motion of the electric pipettor 1 along the slide rail 22 is realized by the rotation of the first anti-backlash nut built in the rotor inside the piercing motor 400, which is not only stable in start and stop, but also small in mechanical vibration, and accurate in program control position, and easy to calibrate, the plurality of electric pipettors 1 on the slide 2 can synchronously operate under an equidistance instruction, and also can asynchronously operate in non-equidistance, that is, each electric pipettor 1 has the capability of independently operating under different pipetting parameters, and can simultaneously adapt to respective vessels and pipetting parameter settings, so that the electric pipetting device can be competent for the highly complicated automatic liquid treatment work.
As shown in fig. 1, 2, 3, and 4, further, at least four electric pipettors 1 are mounted on each sliding table 2, that is, each fixing screw 23 is connected with at least two piercing motors 400, so that each ultra-long fixing screw 23 is coaxially reciprocated and mutually supported by more than two piercing motors 400, thereby not only effectively preventing the shaking and clamping stagnation of the ultra-long fixing screws 23, but also simplifying the mechanism and component costs.
As shown in fig. 5 and 7, in a specific embodiment, the loading mechanism 100 further includes a first screw 102 vertically rotatably mounted on the supporting frame 101 and located inside the supporting point 109, a driven pulley 103 connected above the first screw 102, and a driving pulley 105 connected to the driven pulley 103 through a horizontally disposed timing belt 104 and located outside the supporting point 109, the first motor 106 is coaxially connected to the driving pulley 105, the first motor 106 is provided with an encoder, the first motor 106 can drive the first screw 102 to rotate through the driving pulley 105, the timing belt 104 and the driven pulley 103 in sequence, and the first screw 102 slides up and down relative to the supporting frame 101 through the rotation driving frame 201;
the executing mechanism 200 is positioned inside the fulcrum 109, the pipetting assembly 230 further comprises a dislocation slider 204 which is arranged above the injection tube 202 and connected with the plunger 203, the executing mechanism 200 further comprises a second screw 205 which is rotatably and vertically installed on the rack 201 and is in threaded connection with the dislocation slider 204, the second motor 206 is positioned above the second screw 205 and is connected with the second screw 205, the second motor 206 is provided with an encoder, the second motor 206 can drive the second screw 205 to rotate, the second screw 205 drives the dislocation slider 204 to drive the plunger 203 to move up and down through rotation, the plunger 203 sucks liquid into the pipetting head 300 through upward movement, and the plunger 203 discharges the liquid out of the pipetting head 300 through downward movement, so that liquid suction and discharge are realized.
In this embodiment, since the shifting slider 204 is connected to the plunger 203, when the electric pipettors 1 on the two sliding tables 2 are gathered side by side, the shifting sliders 204 of all the electric pipettors 1 are also sequentially side by side along the central horizontal axis X, and the width of the shifting slider 204 is not greater than the width of the pipetting assembly 230, so that the center distance of the pipetting assembly 230 is not affected by the width of the shifting slider 204, but depends only on the width of the pipetting assembly 230, which is helpful for minimizing the center distance between adjacent pipetting assemblies 230.
As shown in fig. 5 and 7, the support frame 101 further includes a top plate 1012, the driven pulley 103 is mounted on the top of the top plate 1012, the top plate 1012 extends to the outside of the fulcrum 109 to form an extension plate 1014, the width of the extension plate 1014 is greater than that of the top plate 1012, the driving pulley 105 is mounted on the top of the extension plate 1014, the first motor 106 is fixed on the bottom of the extension plate 1014 in an inverted manner, the top plate 1012 and the extension plate 1014 constitute a support plate for supporting the driving pulley 105, the driven pulley 103 and the first motor 106, the support plate is irregular in shape, the size and shape of the top plate 1012 and the extension plate 1014 are set as required, and when the electric pipettes 1 on two slide tables 2 are gathered side by side, the support plates of a plurality of electric pipettes 1 on the same slide table 2 are sequentially spliced.
In one embodiment, as shown in fig. 6, the actuator 200 further comprises a tubular buffer 207, the buffer 207 is inserted into the end of the injection tube 202, i.e. into the end of the injection cavity, the buffer 207 is located below the plunger 203, the gas in the buffer 207 acts as a gas plunger, and the inner diameter of the buffer 207 is smaller than that of the injection cavity, so as to meet the requirement of high precision in a small range.
As shown in fig. 6, in one embodiment, the lower end of the syringe 202 has an insertion wall 2021 capable of being inserted into the pipetting head 300, the insertion wall 2021 is hermetically connected to the pipetting head 300, a through hole 2022 is formed on a side wall of the syringe 202 adjacent to the insertion wall 2021, the through hole 2022 is located above the insertion wall 2021 and below the plunger 203, the buffer 207 is inserted into the insertion wall 2021, the buffer 207 is located below the through hole 2022, the electronic pipette further includes a pressure detection device, the pressure detection device includes a sampling tube 208 and a pressure sensor disposed on the rack 201, one end of the sampling tube 208 is inserted into the through hole 2022 and is communicated with the syringe 202, the other end of the sampling tube 208 is connected to the pressure sensor, the sampling tube 208 is a metal elongated tube, for example, the pressure sensor is a micro-pressure sensor, and has high sensitivity.
In the embodiment, the sampling point of the pressure sensor is arranged at the narrow air gap at the joint of the injection cavity and the pipetting head 300 in the injection tube 202, and because the sampling air gap is very small, under the cooperation of the high-sensitivity pressure sensor, when impurities or clots in liquid block the pipetting head 300, the detection is very easy, and the sensitivity of pressure detection is effectively improved; the pressure detection with high signal-to-noise ratio can also realize bubble false image identification and liquid level detection, and fully meets the main pressure data detection in liquid processing.
As shown in fig. 6, specifically, the outer wall surface of the insertion wall 2021 has two annular protrusions 2023 arranged up and down, the cross-sectional shape of the annular protrusion 2023 is arc-shaped, when the insertion wall 2021 is inserted into the pipetting head 300, the annular protrusion 2023 is attached to the inner wall surface of the pipetting head 300, and an O-ring 2024 is provided between the two annular protrusions 2023 to form a static seal between the syringe 202 and the pipetting head 300. When the pipetting head 300 is loaded, the first motor 106 drives the first screw rod 102 to rotate, and the first screw rod 102 drives the actuator 200 to move downwards through rotation until the two annular protrusions 2023 of the insertion wall 2021 of the syringe 202 are pressed into the pipetting head 300, so that the operation of loading the pipetting head 300 is completed.
As shown in fig. 5, fig. 6 and fig. 7, in one embodiment, the pipetting assembly 230 further comprises a pipetting head withdrawing device, the pipetting head withdrawing device comprises a pressing block 209 capable of axially sliding and sleeved outside the syringe 202, a push rod 210 fixed above the pressing block 209 and capable of axially moving and vertically mounted on the frame 201, an elastic member 211 sleeved outside the push rod 210, and an adjusting ring 212 fixedly sleeved outside the push rod 210, for example, the elastic member 211 is a spring, the adjusting ring 212 is located above the elastic member 211, the adjusting ring 212 and the elastic member 211 are separated by the frame 201, the upper end of the elastic member 211 abuts against the frame 201, the lower end of the elastic member 211 abuts against the pressing block 209, the push rod 210 is located below the dislocation slider 204, the dislocation slider 204 pushes the push rod 210 and the pressing block 209 to apply pressure to the top end of the pipetting head 300 sleeved outside the syringe 202 by moving downwards, so that the pipetting head 300 falls from the syringe 202, the adjusting ring 212 can be pressed against the frame 201 when the top rod 210 moves downwards for a preset distance so as to limit the top rod 210 and the pressing block 209.
In this embodiment, the pressing block 209 of the pipetting head withdrawing device is directly sleeved outside the injection tube 202, the plunger 210 and the pressing block 209 are driven by the dislocation sliding block 204 to move downwards so as to withdraw the pipetting head 300, and the driving device of the plunger 203 (i.e., the dislocation sliding block 204, the second screw 205 and the second motor 206) is directly used as the driving device of the pressing block 209, so that the structure is simple and compact, a pipetting head withdrawing mechanism with a complex structure and a driving electromagnetic component are not required to be separately arranged, and the cost is reduced.
As shown in fig. 6, specifically, the side wall of the adjusting ring 212 is provided with a first jackscrew 213 along the radial direction, the first jackscrew 213 is in threaded connection with the adjusting ring 212 and abuts against the side wall of the ejector rod 210 to fix the adjusting ring 212 and the ejector rod 210 together, when the position of the adjusting ring 212 on the ejector rod 210 needs to be adjusted, the first jackscrew 213 is unscrewed, the adjusting ring 212 is moved up and down, the adjusting ring 212 is moved to a proper position, and then the first jackscrew 213 is screwed to fix the adjusting ring 212 and the ejector rod 210 together, so that the adjustment is very convenient; the side wall of the pressing block 209 is provided with a second jackscrew 214 along the radial direction, the second jackscrew 214 is in threaded connection with the pressing block 209 and props against the side wall of the ejector rod 210 so as to fix the pressing block 209 and the ejector rod 210 together, when the relative position of the ejector rod 210 and the pressing block 209 needs to be adjusted, the second jackscrew 214 is unscrewed, the ejector rod 210 moves up and down, the ejector rod 210 is moved to a proper position and then is screwed, the ejector rod 210 and the pressing block 209 are fixed together, and the adjustment is very convenient.
In this embodiment, since the pressing block 209 is sleeved outside the injection tube 202, when the electric pipettors 1 on the two sliding tables 2 are gathered together side by side, the pressing blocks 209 of all the electric pipettors 1 are sequentially arranged side by side along the central horizontal axis X, and in order to minimize the center distance between the adjacent pipette assemblies 230, the smaller the width of the pressing block 209 is, the better.
As shown in fig. 6, further, a first blocking piece 215 is further disposed on the top of the pressing block 209, when the pressing block 209 pushes the pipetting head 300 downward, the first blocking piece 215 can move downward along with the pressing block 209, a signal conditioning plate 216 is disposed on the lower portion of the rack 201, the signal conditioning plate 216 is located above the pressing block 209, a pipetting head position sensor for detecting the position of the pipetting head 300 is disposed on the signal conditioning plate 216, the pipetting head position sensor detects the position of the pipetting head 300 by detecting the position of the first blocking piece 215, and the signal conditioning plate 216 can transmit a position signal of the pipetting head 300 to the computer. For example, the pipetting head position sensor is a photoelectric sensor.
As shown in fig. 6, further, a second stopper 217 is further disposed at the bottom of the dislocation slider 204, when the dislocation slider 204 drives the plunger 203 to move up and down, the second stopper 217 can move up and down along with the dislocation slider 204, the signal conditioning plate 216 is located below the dislocation slider 204, a plunger position sensor for detecting the position of the plunger 203 is disposed on the signal conditioning plate 216, the plunger position sensor detects the position of the plunger 203 by detecting the position of the second stopper 217, and the signal conditioning plate 216 can transmit a position signal of the plunger 203 to the computer. For example, the plunger position sensor is an opto-electronic sensor.
As shown in fig. 5, 6, and 7, in an embodiment, the actuator 200 further includes an optical axis 218 fixed on the frame 201 and parallel to the second screw 205, two linear bearings disposed in the misalignment slider 204, and a second anti-backlash nut 227 disposed in the misalignment slider 204, where the optical axis 218 is a slide rail of the misalignment slider 204 and is used to guide the misalignment slider 204 to slide, for example, the optical axis 218 is two, the two optical axes 218 are disposed side by side at intervals, the two linear bearings are two, each optical axis 218 passes through each linear bearing, and the second screw 205 passes through the second anti-backlash nut 227 and is screwed with the misalignment slider 204 through the second anti-backlash nut 227. When the second motor 206 drives the second screw 205 to rotate, the second anti-backlash nut 227 drives the offset sliding block 204 to slide up and down along the optical axis 218.
As shown in fig. 6, in an embodiment, the plunger 203 is flexibly connected to the dislocation slider 204, specifically, a connection hole coaxial with the plunger 203 is formed in the dislocation slider 204, a tapered hole with a diameter gradually expanding from bottom to top is formed at a lower end of the connection hole, a connection rod 219 is connected to a top end of the plunger 203, a ball head 220 is connected to a top end of the connection rod 219, the ball head 220 is located in the connection hole and sits on the tapered hole, the diameter of the connection rod 219 is smaller than a minimum diameter of the tapered hole, so that the connection rod 219 can pass through the tapered hole, a rubber plug 221 is fixed in the connection hole, and the rubber plug 221 is located above the ball head 220 and. With such a connection structure, even if the plunger 203 and the misalignment slider 204 are relatively fixed in the axial direction, the plunger 203 is allowed to move in the axial direction while being appropriately shifted in the left and right direction, and the plunger 203 is less likely to be damaged than in a rigid connection.
As shown in fig. 6, the plunger 203 is further connected with the top end of the syringe 202 in a sliding and sealing manner, specifically, a cap-shaped adjusting nut 222 is sleeved on the outer side of the top end of the syringe 202, the plunger 203 can axially and slidably pass through the adjusting nut 222, an O-ring 223 is clamped between the top end of the syringe 202 and the top wall of the adjusting nut 222, the O-ring 223 is located between the side wall of the adjusting nut 222 and the plunger 203, and the syringe 202 and the plunger 203 can be connected with each other in a sliding and sealing manner by the O-ring 223 and the adjusting nut 222, so that dynamic sealing is realized.
As shown in fig. 5 and 7, in a specific embodiment, the frame 201 includes a top frame 2011, a bottom frame 2012 located below the top frame 2011, and a side plate 2013 connected between the top frame 2011 and the bottom frame 2012, where the top frame 2011 and the bottom frame 2012 are both block-shaped, the top frame 2011, the side plate 2013, and the bottom frame 2012 enclose a sliding space 2017, the second motor 206 is fixed on the hollow flange 224 at the top of the top frame 2011, the second screw 205 passes through the sliding space 2017, the upper end of the second screw 205 passes through the top frame 2011 and is connected with the second motor 206, the lower end of the second screw 205 is connected with the bottom frame 2012 through a bearing, for example, the second screw 205 and a rotor of the second motor 206 are an integrated structure; the optical axis 218 penetrates through the sliding space 2017, the upper end of the optical axis 218 is fixedly connected with the top frame 2011, the lower end of the optical axis 218 is fixedly connected with the bottom frame 2012, the dislocation slider 204 is positioned in the sliding space 2017, the injection tube 202 penetrates through the bottom frame 2012 and is fixedly connected with the bottom frame 2012, and the upper end of the injection tube 202 extends into the sliding space 2017; the push rod 210 penetrates through the bottom frame 2012, the adjusting ring 212 is positioned above the bottom frame 2012 and in the sliding space 2017, the adjusting ring 212 can abut against the top surface of the bottom frame 2012 when the push rod 210 moves downwards for a preset distance, the elastic member 211 is positioned below the bottom frame 2012, and the upper end of the elastic member 211 abuts against the bottom surface of the bottom frame 2012;
the bottom of chassis 2012 is equipped with mounting groove 2014, signal conditioning board 216 is located in the mounting groove 2014 of chassis 2012 bottom, still be equipped with perforating hole 2015 that link up from top to bottom on chassis 2012, perforating hole 2015 is adjacent and is linked together with mounting groove 2014, first separation blade 215 and second separation blade 217 aim at from top to bottom with this perforating hole 2015, first separation blade 215 can stretch into in this perforating hole 2015 upwards, detect with the liquid-transfering head position sensor on the signal conditioning board 216, second separation blade 217 can stretch into in this perforating hole 2015 downwards, detect with plunger 203 position sensor on the signal conditioning board 216.
Specifically, for example, the injection tube 202, the ejector rod 210, the optical axes 218 and the second screw 205 are sequentially arranged in a direction close to the support frame 101, the two optical axes 218 are arranged side by side from left to right, the first blocking piece 215 and the second blocking piece 217 are positioned outside the ejector rod 210 and inside the second screw 205, the signal conditioning board 216 is positioned outside the first blocking piece 215 and the second blocking piece 217, the side plate 2013 of the rack 201 is positioned outside the bottom frame 2012, the signal conditioning board 216 is positioned below the side plate 2013, a wire slot 2016 is arranged in the side plate 2013, the wire slot 2016 is communicated with the mounting slot 2014 where the signal conditioning board 216 is positioned, a signal wire passes through the wire slot 2016, one end of the signal wire is connected with the signal conditioning board 216, the other end of the signal wire is connected with the second motor 206, the signal conditioning board 216 transmits a position signal of the plunger 203 to the second motor 206 through the signal wire, and the second motor 206 controls the rotation, to control the initial position of the misplacement slider 204 and thus the position of the plunger 203.
As shown in fig. 5 and 7, in a specific embodiment, the supporting frame 101 is a long-strip hollow channel block, a front side of the channel block is open, a rear side plate 2013 of the channel block is a vertically arranged connecting plate 1011, the supporting slider 229 is fixed on a back surface of the connecting plate 1011, the sliding table 2 is located on an outer side (or referred to as a rear side) of the connecting plate 1011, a vertical guide rail 107 is arranged in the channel block, for example, the guide rail 107 is fixed on a front side surface of the connecting plate 1011, the first screw 102 is arranged in the channel block, a guide rail slider 225 and a nut slider 226 are fixed on a side of the frame 201 facing the channel block, the guide rail slider 225 extends into the channel block and is in sliding fit with the guide rail 107, the nut slider 226 extends into the channel block and is in threaded connection with the first screw 102, and the nut slider 226 drives the frame 201 and the guide rail slider. The combined structure of the support frame 101 and the frame 201 in the embodiment is simple and compact.
For example, there are two rail sliders 225, two rail sliders 225 are disposed at an interval from top to bottom, the upper rail slider 225 is fixed to the rear side of the top frame 2011 of the frame 201, the lower rail slider 225 is fixed to the rear side of the connection plate 1011 of the frame 201, the nut slider 226 is located between the two rail sliders 225, and the nut slider 226 is fixed to the lower rail slider 225. Preferably, the nut sliding block 226 is an anti-backlash nut, and the frame 201 and the guide rail sliding block 225 are of an integrated structure and have high structural strength.
As shown in fig. 6, in one embodiment, the supporting frame 101 further comprises a bottom plate 1013, the top plate 1012 is fixed on the top of the connecting plate 1011, the bottom plate 1013 is fixed on the bottom of the connecting plate 1011, the upper end of the first screw 102 is connected to the top plate 1012 through a bearing, and the lower end of the first screw 102 is connected to the bottom plate 1013 through a bearing. Specifically, the top plate 1012 and the bottom plate 1013 are flanges to facilitate connection.
As shown in fig. 6, the upper portion of the slot block is further provided with a reference position sensor 108 for detecting the position of the rack 201 in the vertical direction, the reference position sensor 108 is located below the ceiling 1012 of the slot block and adjacent to the ceiling 1012 of the slot block, and the reference position sensor 108 is located above the two rail sliders 225, so that the reference position sensor 108 can detect the position of the rack 201 when the rack 201 slides up and down along the rail 107.
Use the utility model discloses an electronic pipettor when moving liquid, in order to avoid the cross contamination of liquid, liquid can not get into the injection chamber in the syringe 202, also can not get into buffer 207, can only be in moving liquid head 300, therefore the range size of liquid treatment depends on moving liquid head 300's volume, and the size of the range of electronic pipettor then depends on plunger 203's volume.
Before imbibing, the position of the plunger 203 needs to be initialized, specifically, the dislocation slider 204 drives the plunger 203 to move downwards, once the signal conditioning plate 216 detects the position of the second stop piece 217 on the dislocation slider 204, a zero position signal is output to the second motor 206, the second motor 206 controls the dislocation slider 204 to stop moving through the second screw 205, and the position is recorded as an initial position (reset) of the dislocation slider 204 and the plunger 203, and when imbibing, the plunger 203 starts to move upwards from the initial position;
when the pipetting head 300 needs to be withdrawn after completing one pipetting operation, the misplacing slide block 204 is allowed to overrun downwards for a few millimeters, at this time, the misplacing slide block 204 drives the mandril 210 downwards, the mandril 210 and the pressing block 209 which is fixedly connected together move downwards, the pipetting head 300 is withdrawn, and the initial position is detected again (reset) before next pipetting.
The above description is only exemplary of the present invention, and is not intended to limit the scope of the present invention. Any person skilled in the art should also realize that such equivalent changes and modifications can be made without departing from the spirit and principles of the present invention. Moreover, it should be noted that the components of the present invention are not limited to the above-mentioned integral application, and various technical features described in the present invention can be selected to be used alone or in combination according to actual needs, so that the present invention naturally covers other combinations and specific applications related to the invention of the present invention.

Claims (10)

1. The electric liquid transfer equipment is characterized by comprising two sliding tables symmetrically arranged on two opposite sides of a central transverse shaft, wherein the two sliding tables are parallel to the central transverse shaft, and each sliding table is provided with at least one electric liquid transfer device;
every electronic pipettor includes loading mechanism and actuating mechanism, loading mechanism including can transversely slide ground with the support frame that the slip table is connected with fix first motor on the support frame, the support frame with the junction of slip table is the fulcrum of electronic pipettor, actuating mechanism including can slide from top to bottom with the frame that the support frame is connected, fix second motor in the frame and move the liquid subassembly, move the liquid subassembly include with the syringe that the frame is connected with vertically insert locate the plunger in the syringe, first motor with the frame is connected and can drive the frame drives the syringe slides from top to bottom for the support frame, the syringe is through the lapse and move the liquid head grafting, the second motor with the plunger is connected and can drive the plunger is in reciprocate in the syringe in order to inhale and discharge liquid, the pipetting assembly is positioned at the central transverse shaft, the second motor is positioned at the outer side of the central transverse shaft and at the inner side of the fulcrum, and the first motor is positioned at the outer side of the fulcrum;
when the electric pipettors on the two sliding tables are gathered side by side, the liquid-transferring assemblies of the electric pipettors on the two sliding tables are sequentially and alternately arranged on the central transverse shaft along the central transverse shaft.
2. An electric pipetting device as recited in claim 1 wherein the central axis of the pipetting assembly passes through and is perpendicular to the central transverse axis, and when the electric pipettes on two of the slide stations are brought together side by side, the center distance between two adjacent pipetting assemblies is not greater than 9 mm.
3. The electric pipetting device as recited in claim 1 wherein each of the slide tables has a plurality of electric pipettes mounted thereon, and when the electric pipettes on two slide tables are gathered side by side, the center distance between two adjacent pipetting modules is smaller than the center distance between the first motors of two adjacent electric pipettes on the same slide table, and the center distance between two adjacent pipetting modules is smaller than the center distance between the second motors of two adjacent electric pipettes on the same slide table.
4. The electric pipetting device according to claim 1, wherein a plurality of electric pipettors are mounted on each of the slide tables, two of the slide tables are a first slide table and a second slide table, respectively, each electric pipettor on the first slide table is a first electric pipettor, each electric pipettor on the second slide table is a second electric pipettor, when the electric pipettors on the two slide tables are gathered side by side, the plurality of first electric pipettors and the plurality of second electric pipettors are sequentially arranged on opposite sides of the central transverse axis along a direction parallel to the central transverse axis, and the plurality of first electric pipettors and the plurality of second electric pipettors are sequentially displaced in a direction parallel to the central transverse axis; the first motors of the plurality of first electric pipettors and the first motors of the plurality of second electric pipettors are respectively arranged side by side in sequence on two opposite sides of the central transverse shaft along the direction parallel to the central transverse shaft, and the first motors of the plurality of first electric pipettors and the first motors of the plurality of second electric pipettors are sequentially staggered in the direction parallel to the central transverse shaft; the second motors of the first electric pipettors and the second motors of the second electric pipettors are respectively arranged on two opposite sides of the central transverse shaft side by side in sequence along the direction parallel to the central transverse shaft, and the second motors of the first electric pipettors and the second motors of the second electric pipettors are staggered in sequence in the direction parallel to the central transverse shaft.
5. The electric pipetting device as recited in any one of claims 1 to 4 wherein each of the slide tables includes two slide table guide rails parallel to the central transverse axis, the two slide table guide rails are spaced apart from each other vertically, the support frame is fixed with a support slider slidably connected to the slide table guide rails, the joint between the support slider and the slide table guide rails is the fulcrum, and the support sliders of any two adjacent electric pipettors on the same slide table are spaced apart vertically and slidably connected to the two slide table guide rails, respectively.
6. The electric pipette device according to claim 5, wherein the length of the support slider is greater than the width of the support frame, the support slider has a protruding portion protruding from the support frame in the width direction of the support frame, an avoidance groove for avoiding the protruding portion of the support slider of another adjacent electric pipette is provided on the support frame of each electric pipette, and when two adjacent electric pipettes on the same slide table are gathered together side by side, the protruding portion of the support slider of one of the electric pipettes protrudes into the avoidance groove of the other electric pipette.
7. The electric pipetting device as recited in any one of claims 1 to 4 wherein each of the slide tables includes two fixed screws parallel to the central horizontal axis, the two fixed screws are spaced vertically, a feed-through motor for the fixed screws to pass through is fixed to the support frame, the feed-through motor is located outside the pivot, a first anti-backlash nut for threaded connection with the fixed screws is provided inside the feed-through motor, the first anti-backlash nut can be driven by a rotor of the feed-through motor to rotate, the feed-through motor slides along the fixed screws when the first anti-backlash nut rotates relative to the fixed screws, and the feed-through motors of any two adjacent electric pipettors are spaced vertically and are respectively in threaded connection with the two fixed screws.
8. The electric pipetting apparatus as recited in any one of claims 1 to 4 wherein the loading mechanism further comprises a first screw rotatably mounted vertically on the support frame and located inside the fulcrum, a driven pulley connected above the first screw, and a driving pulley connected to the driven pulley through a horizontally disposed timing belt and located outside the fulcrum, the first motor being coaxially connected to the driving pulley, the first motor being capable of driving the first screw to rotate through the driving pulley, the timing belt, and the driven pulley in turn, the first screw driving the rack to slide up and down relative to the support frame by rotation;
the actuating mechanism is located the fulcrum is inboard, move the liquid subassembly still including locating the syringe top and with the dislocation slider that the plunger is connected, actuating mechanism still including can rotate ground vertical installation in the frame and with dislocation slider threaded connection's second screw rod, the second motor is located second screw rod top and with the second screw rod is connected, the second motor can drive the second screw rod rotates, the second screw rod is through rotating the drive dislocation slider drives the plunger reciprocates, the plunger is through reciprocating and inhaling or discharging liquid the liquid head.
9. The electric pipetting device of claim 8, wherein the support frame comprises a top plate, the driven pulley is mounted on the top of the top plate, the top plate extends to the outside of the fulcrum to form an extension plate, the width of the extension plate is greater than that of the top plate, the driving pulley is mounted on the top of the extension plate, the first motor is fixed on the bottom of the extension plate in an inverted manner, the top plate and the extension plate form a support plate, and when the electric pipettes on the two sliding tables are gathered together side by side, the support plates of the electric pipettes on the same sliding table are sequentially spliced to form a flat plate.
10. An electric pipetting device as recited in any one of claims 1 to 4 wherein the lower end of the syringe has a socket wall insertable into the pipetting head, and wherein a bore is provided in a side wall of the syringe adjacent to the socket wall, the bore being located above the socket wall and below the plunger, and wherein the actuator further comprises a pressure detecting device including a sampling tube and a pressure sensor provided in the frame, one end of the sampling tube being inserted into the bore and communicating with the syringe, and the other end of the sampling tube being connected to the pressure sensor.
CN202020731929.2U 2020-05-07 2020-05-07 Electric liquid transfer equipment Active CN212083464U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114164086A (en) * 2021-12-07 2022-03-11 江苏领坤生物科技有限公司 Liquid transfer platform for full-automatic liquid transfer workstation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114164086A (en) * 2021-12-07 2022-03-11 江苏领坤生物科技有限公司 Liquid transfer platform for full-automatic liquid transfer workstation

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