CN114127046A - 用于生物成像的荧光系统及其用途 - Google Patents
用于生物成像的荧光系统及其用途 Download PDFInfo
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- CN114127046A CN114127046A CN202080051807.1A CN202080051807A CN114127046A CN 114127046 A CN114127046 A CN 114127046A CN 202080051807 A CN202080051807 A CN 202080051807A CN 114127046 A CN114127046 A CN 114127046A
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- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K47/545—Heterocyclic compounds
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- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- C07C229/44—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by unsaturated carbon chains
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- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/18—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
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- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
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- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
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- C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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- Public Health (AREA)
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- General Physics & Mathematics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
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- Materials Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1910239.1A GB201910239D0 (en) | 2019-07-17 | 2019-07-17 | Fluorescent systems for biological imaging and uses thereof |
| GB1910239.1 | 2019-07-17 | ||
| PCT/GB2020/051694 WO2021009506A1 (en) | 2019-07-17 | 2020-07-14 | Fluorescent systems for biological imaging and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114127046A true CN114127046A (zh) | 2022-03-01 |
Family
ID=67700264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080051807.1A Pending CN114127046A (zh) | 2019-07-17 | 2020-07-14 | 用于生物成像的荧光系统及其用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220347299A1 (https=) |
| EP (1) | EP3921373A1 (https=) |
| JP (2) | JP2022541453A (https=) |
| KR (1) | KR20220036949A (https=) |
| CN (1) | CN114127046A (https=) |
| AU (1) | AU2020312791B2 (https=) |
| BR (1) | BR112022000364A2 (https=) |
| CA (1) | CA3140662A1 (https=) |
| GB (1) | GB201910239D0 (https=) |
| MX (1) | MX2022000654A (https=) |
| WO (1) | WO2021009506A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115010678A (zh) * | 2022-06-21 | 2022-09-06 | 南阳理工学院 | 不对称合成含有季碳手性中心烯丙基吖内酯衍生物的方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4281449A1 (en) * | 2021-01-20 | 2023-11-29 | Lightox Limited | Protected hdac (histone deacetylase) inhibitors |
| CN116239584B (zh) * | 2023-02-15 | 2024-06-11 | 东南大学 | 一种单体m1、二聚体d1及其制备方法和应用 |
| GB202313555D0 (en) * | 2023-09-05 | 2023-10-18 | Lightox Ltd | Compositions and methods for the treatment and prevention of bacterial infections casued by gram-positive bacteria |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170217893A1 (en) * | 2014-10-10 | 2017-08-03 | High Force Research Limited | Fluorescent Synthetic Retinoids |
| US20180156811A1 (en) * | 2015-06-24 | 2018-06-07 | The Hong Kong University Of Science And Technology | Aie luminogens for visualization and treatment of cancer |
| CN109843291A (zh) * | 2016-08-09 | 2019-06-04 | 杜伦大学 | 合成类视色素(细胞调节) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5395556A (en) * | 1990-12-12 | 1995-03-07 | Enichem S.P.A. | Tricyanovinyl substitution process for NLO polymers |
| IL106473A0 (en) * | 1992-08-11 | 1993-11-15 | Basf Ag | Acetylene derivatives and crop protection agents containing them |
| JP2004123579A (ja) * | 2002-09-30 | 2004-04-22 | Fuji Photo Film Co Ltd | トラン誘導体、およびそれを用いた光学材料 |
| JP2004250399A (ja) * | 2003-02-21 | 2004-09-09 | Fuji Photo Film Co Ltd | チオフェン化合物、並びに非線形光学材料及び電気光学材料 |
| JP2004317777A (ja) * | 2003-04-16 | 2004-11-11 | Fuji Photo Film Co Ltd | 光導波路及びその製造方法 |
| JP2005070481A (ja) * | 2003-08-26 | 2005-03-17 | Fuji Photo Film Co Ltd | 化合物、非線形光学材料及び電気光学材料 |
| CN106588789A (zh) * | 2016-12-07 | 2017-04-26 | 西京学院 | 一种以三唑为核心的染料敏化剂分子及其制备方法 |
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2019
- 2019-07-17 GB GBGB1910239.1A patent/GB201910239D0/en not_active Ceased
-
2020
- 2020-07-14 WO PCT/GB2020/051694 patent/WO2021009506A1/en not_active Ceased
- 2020-07-14 KR KR1020227003505A patent/KR20220036949A/ko active Pending
- 2020-07-14 AU AU2020312791A patent/AU2020312791B2/en active Active
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| US20170217893A1 (en) * | 2014-10-10 | 2017-08-03 | High Force Research Limited | Fluorescent Synthetic Retinoids |
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| CN115010678A (zh) * | 2022-06-21 | 2022-09-06 | 南阳理工学院 | 不对称合成含有季碳手性中心烯丙基吖内酯衍生物的方法 |
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| Publication number | Publication date |
|---|---|
| JP2025121960A (ja) | 2025-08-20 |
| AU2020312791A1 (en) | 2022-01-06 |
| EP3921373A1 (en) | 2021-12-15 |
| GB201910239D0 (en) | 2019-08-28 |
| JP2022541453A (ja) | 2022-09-26 |
| AU2020312791B2 (en) | 2026-02-19 |
| KR20220036949A (ko) | 2022-03-23 |
| WO2021009506A1 (en) | 2021-01-21 |
| CA3140662A1 (en) | 2021-01-21 |
| MX2022000654A (es) | 2022-03-11 |
| BR112022000364A2 (pt) | 2022-05-10 |
| US20220347299A1 (en) | 2022-11-03 |
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