CN114126643A - 包含溶菌酶的广谱抗菌药物制剂及其使用方法 - Google Patents

包含溶菌酶的广谱抗菌药物制剂及其使用方法 Download PDF

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Publication number
CN114126643A
CN114126643A CN202080048142.9A CN202080048142A CN114126643A CN 114126643 A CN114126643 A CN 114126643A CN 202080048142 A CN202080048142 A CN 202080048142A CN 114126643 A CN114126643 A CN 114126643A
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China
Prior art keywords
formulation
lysozyme
pharmaceutical formulation
weight
pharmaceutical
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CN202080048142.9A
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English (en)
Chinese (zh)
Inventor
第欧根尼·艾巴尔-巴蒂斯塔
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Aibar Ecological Technology Co ltd
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Aibar Ecological Technology Co ltd
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Publication of CN114126643A publication Critical patent/CN114126643A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202080048142.9A 2019-05-28 2020-05-28 包含溶菌酶的广谱抗菌药物制剂及其使用方法 Pending CN114126643A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962853215P 2019-05-28 2019-05-28
US62/853,215 2019-05-28
PCT/IB2020/055083 WO2020240472A1 (en) 2019-05-28 2020-05-28 Wide-spectrum antibacterial pharmaceutical formulations comprising lysozyme and methods of using the same

Publications (1)

Publication Number Publication Date
CN114126643A true CN114126643A (zh) 2022-03-01

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Family Applications (1)

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CN202080048142.9A Pending CN114126643A (zh) 2019-05-28 2020-05-28 包含溶菌酶的广谱抗菌药物制剂及其使用方法

Country Status (12)

Country Link
US (3) US20200376094A1 (enExample)
EP (1) EP3976093A4 (enExample)
JP (3) JP7768769B2 (enExample)
CN (1) CN114126643A (enExample)
AR (1) AR119031A1 (enExample)
BR (1) BR112021024001A2 (enExample)
CA (1) CA3145530A1 (enExample)
CO (1) CO2021017958A2 (enExample)
IL (1) IL288531A (enExample)
MX (1) MX2021014634A (enExample)
TW (1) TW202110474A (enExample)
WO (1) WO2020240472A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112805027B (zh) * 2020-04-27 2023-10-10 广州新创忆药物临床研究有限公司 一种抗新冠病毒感染的药物与应用
WO2021217702A1 (zh) * 2020-04-27 2021-11-04 广州新创忆药物临床研究有限公司 一种预防或治疗covid-19新冠肺炎的药物、食物及其应用
WO2023133412A2 (en) * 2022-01-05 2023-07-13 Prophase Labs, Inc. Compositions having synergistic anti-viral action and methods for treating coronavirus
CN114503981A (zh) * 2022-01-07 2022-05-17 上海膜益信息科技有限公司 一种不分层防霉液及其制备方法和应用

Citations (4)

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Publication number Priority date Publication date Assignee Title
CN1557485A (zh) * 2004-01-30 2004-12-29 大连帝恩生物工程有限公司 基因重组人溶菌酶在消除病原微生物感染炎症上的应用
UA48016U (ru) * 2010-01-25 2010-02-25 Илона Васильевна Ковач Способ профилактики кариеса зубов у детей 3-6 лет
UA68612U (ru) * 2012-02-07 2012-03-26 Дмитрий Викторович Дудар Способ лечения хронического рецидивирующего афтозного стоматита у больных целиакией
CN107899006A (zh) * 2017-11-28 2018-04-13 四川清舒乐科技有限公司 冲洗鼻腔的药物组合物及其制备方法

Family Cites Families (9)

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DK501686A (da) * 1986-10-20 1988-04-21 Otto Melchior Poulsen Enzymholdigt, baktericidt middel samt tandplejemidler og saarbehandlingsmidler, som indeholder det
PT1755576E (pt) * 2004-04-08 2011-10-19 Dermcare Vet Pty Ltd Composições antimicrobianas e métodos para a sua utilização
CN1583170A (zh) * 2004-06-10 2005-02-23 安米 用于抗病毒抗耐药菌的人溶菌酶药物及其制法
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
US8097434B2 (en) * 2007-10-19 2012-01-17 Becton, Dickinson And Company Methods for the detection of beta-lactamases
CN102223876A (zh) * 2008-09-26 2011-10-19 纳米生物公司 纳米乳剂治疗性组合物及其使用方法
CN111973484A (zh) * 2013-03-12 2020-11-24 普莱玛疗法公司 包含螯合剂和碱的牙用组合物
JP7055814B2 (ja) * 2017-02-28 2022-04-18 プリシジョンバイオティクス・グループ・リミテッド 呼吸器ウイルス感染症に対する免疫応答を有利に調節することができるビフィドバクテリウム・ロンガム
US20200215169A1 (en) * 2017-07-17 2020-07-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Antibacterial methods and related kits

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1557485A (zh) * 2004-01-30 2004-12-29 大连帝恩生物工程有限公司 基因重组人溶菌酶在消除病原微生物感染炎症上的应用
UA48016U (ru) * 2010-01-25 2010-02-25 Илона Васильевна Ковач Способ профилактики кариеса зубов у детей 3-6 лет
UA68612U (ru) * 2012-02-07 2012-03-26 Дмитрий Викторович Дудар Способ лечения хронического рецидивирующего афтозного стоматита у больных целиакией
CN107899006A (zh) * 2017-11-28 2018-04-13 四川清舒乐科技有限公司 冲洗鼻腔的药物组合物及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KO KY等: "Ethylenediaminetetraacetate and lysozyme improves antimicrobial activities of ovotransferrin against Escherichia coli O157:H7", POULT SCI, pages 406 - 414 *
赵电波等: "天然生物防腐剂溶菌酶的改性研究进展", 中国食品添加剂, no. 05, pages 200 - 204 *

Also Published As

Publication number Publication date
US20200376094A1 (en) 2020-12-03
TW202110474A (zh) 2021-03-16
BR112021024001A2 (pt) 2022-01-25
WO2020240472A1 (en) 2020-12-03
CO2021017958A2 (es) 2022-01-17
EP3976093A4 (en) 2023-07-05
AR119031A1 (es) 2021-11-17
CA3145530A1 (en) 2020-12-03
US20240066105A1 (en) 2024-02-29
EP3976093A1 (en) 2022-04-06
JP2026021451A (ja) 2026-02-10
JP2025038034A (ja) 2025-03-18
IL288531A (en) 2022-01-01
JP7768769B2 (ja) 2025-11-12
MX2021014634A (es) 2022-07-04
US20220362354A1 (en) 2022-11-17
JP2022534776A (ja) 2022-08-03

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