BR112021024001A2 - Formulações farmacêuticas antibacterianas de grande espectro compreendendo lisozima e métodos de uso da mesma - Google Patents

Formulações farmacêuticas antibacterianas de grande espectro compreendendo lisozima e métodos de uso da mesma

Info

Publication number
BR112021024001A2
BR112021024001A2 BR112021024001A BR112021024001A BR112021024001A2 BR 112021024001 A2 BR112021024001 A2 BR 112021024001A2 BR 112021024001 A BR112021024001 A BR 112021024001A BR 112021024001 A BR112021024001 A BR 112021024001A BR 112021024001 A2 BR112021024001 A2 BR 112021024001A2
Authority
BR
Brazil
Prior art keywords
lysozyme
methods
treatment
broad spectrum
infections
Prior art date
Application number
BR112021024001A
Other languages
English (en)
Inventor
Diogenes Aybar-Batista
Original Assignee
Aybar Ecotechnologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aybar Ecotechnologies Corp filed Critical Aybar Ecotechnologies Corp
Publication of BR112021024001A2 publication Critical patent/BR112021024001A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

formulações farmacêuticas antibacterianas de grande espectro compreendendo lisozima e métodos de uso da mesma. uma formulação farmacêutica antibacteriana de amplo espectro que compreende lisozima e métodos de tratamento para prevenir ou curar doenças de etiologia bacteriana. excipientes fornecidos na formulação farmacêutica compreendendo lisozima aumentam a estabilidade e eficácia da lisozima para o tratamento de infecções bacterianas em um mamífero. a formulação farmacêutica que compreende lisozima não produz efeitos secundários prejudiciais nos tecidos ou órgãos durante o tratamento prolongado. a formulação pode ser usada para tratar infecções bacterianas da pele, regiões mucosas e administrada na corrente sanguínea de um paciente, incluindo infecções respiratórias. a formulação é útil no tratamento de infecções bacterianas, incluindo aquelas que ocorrem junto com infecções virais, particularmente infecções virais com um componente respiratório, incluindo covid-19.
BR112021024001A 2019-05-28 2020-05-28 Formulações farmacêuticas antibacterianas de grande espectro compreendendo lisozima e métodos de uso da mesma BR112021024001A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962853215P 2019-05-28 2019-05-28
PCT/IB2020/055083 WO2020240472A1 (en) 2019-05-28 2020-05-28 Wide-spectrum antibacterial pharmaceutical formulations comprising lysozyme and methods of using the same

Publications (1)

Publication Number Publication Date
BR112021024001A2 true BR112021024001A2 (pt) 2022-01-25

Family

ID=73551002

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021024001A BR112021024001A2 (pt) 2019-05-28 2020-05-28 Formulações farmacêuticas antibacterianas de grande espectro compreendendo lisozima e métodos de uso da mesma

Country Status (12)

Country Link
US (3) US20200376094A1 (pt)
EP (1) EP3976093A4 (pt)
JP (1) JP2022534776A (pt)
CN (1) CN114126643A (pt)
AR (1) AR119031A1 (pt)
BR (1) BR112021024001A2 (pt)
CA (1) CA3145530A1 (pt)
CO (1) CO2021017958A2 (pt)
IL (1) IL288531A (pt)
MX (1) MX2021014634A (pt)
TW (1) TW202110474A (pt)
WO (1) WO2020240472A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112805027B (zh) * 2020-04-27 2023-10-10 广州新创忆药物临床研究有限公司 一种抗新冠病毒感染的药物与应用
WO2023133412A2 (en) * 2022-01-05 2023-07-13 Prophase Labs, Inc. Compositions having synergistic anti-viral action and methods for treating coronavirus
CN114503981A (zh) * 2022-01-07 2022-05-17 上海膜益信息科技有限公司 一种不分层防霉液及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1557485A (zh) * 2004-01-30 2004-12-29 大连帝恩生物工程有限公司 基因重组人溶菌酶在消除病原微生物感染炎症上的应用
WO2005097094A1 (en) * 2004-04-08 2005-10-20 Dermcare-Vet Pty Ltd Antimicrobial compositions and methods for their use
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
WO2010036938A2 (en) * 2008-09-26 2010-04-01 Nanobio Corporation Nanoemulsion therapeutic compositions and methods of using the same
UA48016U (ru) * 2010-01-25 2010-02-25 Илона Васильевна Ковач Способ профилактики кариеса зубов у детей 3-6 лет
UA68612U (ru) * 2012-02-07 2012-03-26 Дмитрий Викторович Дудар Способ лечения хронического рецидивирующего афтозного стоматита у больных целиакией
KR20190123267A (ko) * 2017-02-28 2019-10-31 앨러멘터리 헬스 리미티드 호흡기 바이러스 감염에 대한 면역 반응을 유익하게 조절할 수 있는 비피도박테리움 롱검
US20200215169A1 (en) * 2017-07-17 2020-07-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Antibacterial methods and related kits
CN107899006A (zh) * 2017-11-28 2018-04-13 四川清舒乐科技有限公司 冲洗鼻腔的药物组合物及其制备方法

Also Published As

Publication number Publication date
EP3976093A1 (en) 2022-04-06
TW202110474A (zh) 2021-03-16
MX2021014634A (es) 2022-07-04
US20200376094A1 (en) 2020-12-03
AR119031A1 (es) 2021-11-17
US20220362354A1 (en) 2022-11-17
WO2020240472A1 (en) 2020-12-03
JP2022534776A (ja) 2022-08-03
IL288531A (en) 2022-01-01
EP3976093A4 (en) 2023-07-05
CN114126643A (zh) 2022-03-01
CA3145530A1 (en) 2020-12-03
US20240066105A1 (en) 2024-02-29
CO2021017958A2 (es) 2022-01-17

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